Sensors and Actuators Reports最新文献

{"title":"Low-cost paper-based sensors modified with curcumin for the detection of ochratoxin a in beverages","authors":"Danilo M. dos Santos ,&nbsp;Fernanda L. Migliorini ,&nbsp;Andrey Coatrini-Soares ,&nbsp;Juliana C. Soares ,&nbsp;Luiz H.C. Mattoso ,&nbsp;Osvaldo N. Oliveira ,&nbsp;Daniel S. Correa","doi":"10.1016/j.snr.2023.100184","DOIUrl":"10.1016/j.snr.2023.100184","url":null,"abstract":"<div><p>Detection of mycotoxins in food is essential due to their potential harm to human and animal health. However, developing affordable and rapid methods for their detection, particularly with the necessary selectivity to differentiate between various mycotoxins, remains a challenge. Herein, we present low-cost paper-based sensing platforms modified with curcumin, a natural polyphenolic compound, for the electrochemical and optical detection of ochratoxin A (OTA). By exploiting the fluorescence quenching effect of OTA on curcumin through Förster energy transfer, we successfully conducted optical detection with LODs of 0.09 ng mL⁻¹ and a linear range of 0.5 to 15 ng mL⁻¹. Additionally, by using electrochemical impedance spectroscopy and a portable instrument, we detected OTA with a limit of detection (LOD) as low as 0.045 ng mL⁻¹. These sensitivity levels meet the requirements established by food regulatory agencies for monitoring food quality in relation to OTA contamination. Our curcumin-modified paper-based sensors offer a compelling combination of simplicity in manufacturing and cost-effectiveness, underscoring their potential for routine food quality monitoring, especially concerning ochratoxin A.</p></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"7 ","pages":"Article 100184"},"PeriodicalIF":5.9,"publicationDate":"2023-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666053923000474/pdfft?md5=556755e63432b7fde634ddd077994de5&pid=1-s2.0-S2666053923000474-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139064131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Graphitic carbon nitride and its nanocomposites-based sensors for detection of pharmaceutical effluents in food, ecological and biological samples: A mini-review","authors":"Mohanraj Jagannathan,&nbsp;Sushmee Badhulika","doi":"10.1016/j.snr.2023.100183","DOIUrl":"10.1016/j.snr.2023.100183","url":null,"abstract":"<div><p>Pharmaceutical effluents (PEs) have emerged as a global threat to mankind owing to their adverse health effects on humans. Generally, PEs are acquainted with the environment via direct emissions from drug manufacturing plants, unplanned disposal of unused or expired medicines, unprocessed patient/animal excretion, aquafarming, etc. Unlike other pollutions, PE-based contaminations can lead to catastrophic consequences via genotoxic, ecotoxicological, mutagenic effects, etc., causing behavioural changes, reproductive damage, and chronic damage. Therefore, a susceptible detection platform for PE traces in different sources like water bodies, human biofluids, etc., is in high demand. Owing to their high surface area, chemical stability, and electrocatalytic activity, the 2D graphitic carbon nitride (gCN) has gathered significant research interest. It has been examined for the electrochemical detection of PE traces in different ecological and biological samples. In this mini-review, we discuss the exciting advancements in the design and fabrication of gCN and its nanocomposite-based electrochemical sensors for other trace-level detection of different PEs in ecological and biological systems. The table in this review provides a clear insight into the reported gCN-based electrochemical sensors and their performance analysis towards sensing of EFs. The anticipated developments are discussed with current limitations in gCN-based electrochemical sensors for PE detection.</p></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"7 ","pages":"Article 100183"},"PeriodicalIF":5.9,"publicationDate":"2023-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666053923000462/pdfft?md5=fa7d2030d70523e1a9d6458c939eea14&pid=1-s2.0-S2666053923000462-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138555864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing gas sensing performance of tungsten trioxide (WO3) nanofibers through diameter and crystallinity control","authors":"Bingxin Yang ,&nbsp;Thien-Toan Tran ,&nbsp;JoAnna Milam-Guerrero ,&nbsp;Dung T. To ,&nbsp;Thomas Stahovich ,&nbsp;Nosang V. Myung","doi":"10.1016/j.snr.2023.100182","DOIUrl":"https://doi.org/10.1016/j.snr.2023.100182","url":null,"abstract":"<div><p>Tungsten trioxide (WO₃) is one of most widely investigated metal oxide semiconductors as gas sensing material because of tunable sensing performance toward different analytes through composition modulation (<em>e.g.,</em> dopants) and various morphology and crystallinity. In this work, we synthesized WO₃ nanofibers with different diameter and crystallinity through electrospinning of ammonium metatungstate hydrate (AMH)/polyvinyl pyrrolidone (PVP) nanofibers via design of experiments (DOE) followed by thermal heat treatment with the smaller average diameter being 23.0 nm. Through varying the calcination process, WO₃ nanofibers with different crystallinity were also synthesized, with the smaller average grain size being 23.0 nm. These nanofibers were then exposed to many analytes (<em>i.e.,</em> H₂S, acetone, toluene, ethanol, ethyl benzene, NO₂, NO, and methane) under different operating temperatures (<em>i.e.,</em> 250 to 450 °C) to investigate their effect toward sensing response. These systematic studies indicated that nanocrystalline WO₃ nanofibers with the smaller diameter (<em>i.e.,</em> 20 nm) and/or smaller average grain sizes (<em>i.e.,</em>18.7 nm) exhibited best sensing performance independent of target analytes. The barrier energy was also correlated with the gas sensing performance experimentally.</p></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"7 ","pages":"Article 100182"},"PeriodicalIF":5.9,"publicationDate":"2023-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666053923000450/pdfft?md5=325b3b6720b9defc81fb89861f3febe4&pid=1-s2.0-S2666053923000450-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138501732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rapid, sensitive and highly specific diagnosis of Moraxella catarrhalis by recombinase polymerase amplification-based biosensor and fluorescence detection","authors":"Lei Yu ,&nbsp;Fei Xiao ,&nbsp;Bo Peng ,&nbsp;Nan Jia ,&nbsp;Jin Fu ,&nbsp;Min Chen ,&nbsp;Yi Wang ,&nbsp;Juan Zhou ,&nbsp;Lihui Meng","doi":"10.1016/j.snr.2023.100181","DOIUrl":"https://doi.org/10.1016/j.snr.2023.100181","url":null,"abstract":"<div><p><em>Moraxella catarrhalis</em> (<em>M. catarrhalis</em>) was an underestimated respiratory infection pathogen that has been largely overlooked. The limited availability of rapid and sensitive detection methodologies has hindered <em>M. catarrhalis</em> diagnostic in clinical settings and contributed to its underestimation. To address this issue, we devised two recombinase polymerase amplification (RPA)-based assays for rapid, sensitive and reliable detection of <em>M. catarrhalis</em>, termed <em>M. catarrhalis</em>-RPA-Flu and <em>M. catarrhalis</em>-RPA-LFB, which utilized fluorescence and nanoparticle-based lateral flow biosensor (LFB) for reporting the detection results, respectively. In both assays, the specific <em>copB</em> gene of <em>M. catarrhalis</em> was amplified at 37°C for only a period of 20 minutes. In <em>M. catarrhalis</em>-RPA-Flu system, the detection results were analyzed by either using a real-time fluorescent detector or by direct observation using the naked eye under blue light, while, in <em>M. catarrhalis</em>-RPA-LFB system, biosensors were used for interpreting the results without any specialized instruments. Both methods were able to finalize the entire detection process within a duration of 40 minutes, detect down to 35 fg genomic DNA per test, and correctly differentiate <em>M. catarrhalis</em> from non-<em>M. catarrhalis</em> strains. The feasibility of both techniques was validated by analyzing 96 BALF (Broncho alveolar lavage fluid) samples in clinical settings. Collectively, the newly developed two RPA-based assays exhibit great potential for rapid and accurate identification of <em>M. catarrhalis</em> in standard microbiology laboratories as well as diagnosis of <em>M. catarrhalis</em> infection in clinical settings.</p></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"7 ","pages":"Article 100181"},"PeriodicalIF":5.9,"publicationDate":"2023-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666053923000449/pdfft?md5=3dd4a6fb1c966b3773ec1651bd45791a&pid=1-s2.0-S2666053923000449-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138490257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detecting homocysteine in cardiovascular disease using aptasensors: A review","authors":"Sara Ranjbari ,&nbsp;Tannaz Jamialahmadi ,&nbsp;Reza Arefinia ,&nbsp;Amirhossein Sahebkar","doi":"10.1016/j.snr.2023.100178","DOIUrl":"https://doi.org/10.1016/j.snr.2023.100178","url":null,"abstract":"<div><p>Homocysteine (Hcy) is a non-protein sulfuric amino acid that is produced as a by-product of methionine transmethylation. Increased levels of Hcy in human serum result in hyperhomocysteinemia, which is an indicator for coagulation problems and cardiovascular diseases (CVDs). Therefore, serum Hcy has been suggested as a biomarker to determine redox dysfunction in humans. However, it is necessary to use a reliable method to determine the amount of Hcy in biological fluids and its significance in health and disease. Several studies have used aptamer-based electrochemical sensors (aptasensors) to detect Hcy. The focus of these studies was on speeding up detection and creating novel detection techniques. Apatasensing technology has the potential to improve the diagnosis and treatment of cardiovascular problems. The goal of this review is to provide a general overview of the various Hcy aptasensors in relation to their linear range, detection abilities, and potential medical uses.</p></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"6 ","pages":"Article 100178"},"PeriodicalIF":5.9,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666053923000413/pdfft?md5=94623bd5a3af07b1e0ed3203589560be&pid=1-s2.0-S2666053923000413-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91728189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanostructured thin films as electrochemical sensors and biosensors for milk analysis","authors":"M.L. Rodriguez-Mendez","doi":"10.1016/j.snr.2023.100179","DOIUrl":"https://doi.org/10.1016/j.snr.2023.100179","url":null,"abstract":"<div><p>During the last decade, nanomaterials and supramolecular assemblies have received considerable attention in different fields of sensing applications. The interest of supramolecular assemblies arises from the exceptional performances of nanostructured films based on such assemblies, which are related to both their well-controlled structure and their large surface area. These characteristics increase the number of active sites and facilitate the charge transport pathways. In addition, supramolecular assemblies can be used to prepare multicomponent sensing layers formed by materials with complementary activity. Finally, supramolecular films are highly efficient platforms for enzyme immobilization leading to highly sensitive biosensing.</p><p>This paper describes the main concepts and approaches related to the development of supramolecular sensing layers in electrochemical sensors and biosensors. Different techniques commonly employed to develop supramolecular sensing layers, such as Self-assembling, Layer-by-layer and Langmuir-Blodgett, are described and their role as electron mediators in biosensors is revised using milk as an example of the target analyte. Using this approach, enzymes are immobilized in a biomimetic environment, giving rise to efficient biosensors able to detect glucose, galactose or lactose in milk with high degree of selectivity and low limits of detection.</p><p>We also include a brief discussion of the possibilities of the integration of supramolecular assemblies into sensor arrays as the core of electronic and bioelectronic tongues. The advantages of these systems are related to their fast responses and their capability to detect many components in a single measurement. The expected limitations mainly related to the fouling of the electrodes, are also discussed.</p></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"6 ","pages":"Article 100179"},"PeriodicalIF":5.9,"publicationDate":"2023-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666053923000425/pdfft?md5=d1e8544e59f01a98e76533962718764b&pid=1-s2.0-S2666053923000425-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91728188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An AIE active imidazole conjugated α-cyanostilbene based sensor for the selective and sensitive detection of picric acid in an aqueous medium","authors":"Selin Manoj Kumar,&nbsp;Sathiyanarayanan Kulathu Iyer","doi":"10.1016/j.snr.2023.100177","DOIUrl":"https://doi.org/10.1016/j.snr.2023.100177","url":null,"abstract":"<div><p>Due to increasing pollution threats, terrorism-sensitive rapid sensing of aromatic nitro explosives (picric acid) has gained predominant significance in environmental safety. Herein, imidazole-derived monofunctional fluorescent sensor 2-(4-aminophenyl)-3-(3-(4,5-diphenyl-1<em>H</em>-imidazol-2-yl)-2-hydroxyphenyl) acrylonitrile (<strong>ADHA)</strong> was successfully developed for the selective recognition of explosive picric acid. The D-π-A configuration of <strong>ADHA</strong> facilitates extraordinary photophysical properties with remarkable aggregation-induced emission (AIE). The detection process is induced by the photon-induced electron transfer (PET) and resonance energy transfer (RET) and results in the generation of <strong>ADHA</strong>+PA complex. The structural relationship and the photophysical properties of <strong>ADHA</strong> were extensively studied by DFT (Density Functional Theory) methods and spectroscopic analysis. It has been calculated that the detection limit of the formed complex is 6.26 nM. In addition, ¹H NMR titrations DFT calculations, and HRMS analysis were performed to understand the detection mechanism better. Test strip-aided detection and invisible ink applications confirmed that <strong>ADHA</strong> is a versatile sensor for sensitively detecting picric acid without sophisticated instruments. In addition, <strong>ADHA</strong> was implemented to detect PA in real water samples with remarkable recovery.</p></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"6 ","pages":"Article 100177"},"PeriodicalIF":5.9,"publicationDate":"2023-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666053923000401/pdfft?md5=dc9ee271531b158ab41117437af8ca54&pid=1-s2.0-S2666053923000401-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91684800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electroanalytical Overview: The Electroanalytical Detection of Oxalate","authors":"Robert D. Crapnell,&nbsp;Prashanth S. Adarakatti,&nbsp;Craig E. Banks","doi":"10.1016/j.snr.2023.100176","DOIUrl":"https://doi.org/10.1016/j.snr.2023.100176","url":null,"abstract":"<div><p>The sensing of oxalate within urine has been recognised as one of the most important determinations in the investigation of patients with hyperoxaluria. However, current approaches have reported expensive, time consuming, occasionally poor selectivity and are subject to large inaccuracies if great care is not exercised in the handling and measurement of samples. One approach is the use of electroanalytical sensors, which present rapid but highly selective and sensitive outputs, are economical and miniature providing portable sensing platforms to support on-site analysis. In this minireview, recent advances in the electroanalytical sensing of oxalate are presented, overviewing recent electrode configurations and real sample analysis; comparisons to other analytical methods are presented. Finally, the conclusions and future perspective of this field are described in brief.</p></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"6 ","pages":"Article 100176"},"PeriodicalIF":5.9,"publicationDate":"2023-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666053923000395/pdfft?md5=4185ced973ed06dff7765fa2fb54e5f3&pid=1-s2.0-S2666053923000395-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92098417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emergence of MXene-based electrochemical biosensors for biomolecule and pathogen detection","authors":"Aibobek Seitak ,&nbsp;Shaohong Luo ,&nbsp;Ning Cai ,&nbsp;Kin Liao ,&nbsp;Anna-Maria Pappa ,&nbsp;Sungmun Lee ,&nbsp;Vincent Chan","doi":"10.1016/j.snr.2023.100175","DOIUrl":"https://doi.org/10.1016/j.snr.2023.100175","url":null,"abstract":"<div><p>MXenes, is an attractive new class of two-dimensional (2D) materials, discovered in 2011. Since then, owing to their unique combination of properties, such as high specific area, high electrical conductivity, tunable hydrophilicity, tunable chemical composition, and potential cytocompatibility, MXenes have made a deep impact on various fields ranging from electronics to energy and more recently to biotechnology. A typical example for the latter, is their use as electroactive biointerfaces in a number of biosensor setups, exhibiting remarkable analytical performance. In particular, MXene-based nanocomposites can serve as bioreceptors, electrochemical transducers or amplification probes towards translating molecular recognition of biological targets into detectable signals, leading to ultrasensitive biosensors for probing biomarkers, or pathogens. This concise review highlights the recent advances of MXene-based electrochemical biosensors for highly selective and sensitive detection of nucleic acids, proteins and pathogens pertaining to biomarker identification and clinical diagnostics. In particular, the effects of synthetic routes, surface chemistry, nanocomposite design, and fabrication methods of MXenes on the resulting relationship between biointerfacial structure, electrochemical properties and device performance is discussed, providing unique perspectives and design criteria for the next wave of biosensors.</p></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"6 ","pages":"Article 100175"},"PeriodicalIF":5.9,"publicationDate":"2023-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666053923000383/pdfft?md5=1484e760a72cee161f9dad9261cec176&pid=1-s2.0-S2666053923000383-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91684474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Theoretical insights into gas sensing properties of MXene","authors":"Julaiba Tahsina Mazumder ,&nbsp;Ravindra Kumar Jha","doi":"10.1016/j.snr.2023.100174","DOIUrl":"10.1016/j.snr.2023.100174","url":null,"abstract":"<div><p>MXene has emerged as a prominent two-dimensional material with vast potential for diverse applications, garnering significant attention within the scientific community. This attention is due to its unique surface structure and its capacity for surface modification through functionalization, as well as its exceptional conductivity and elasticity. Extensive theoretical and experimental studies have been conducted to explore the gas sensing capabilities of various MXenes, and this review aims to present the latest advancements in this field through the lens of density functional theory. The review begins by providing a detailed explanation of the theoretical calculations involved, including the various available computational software options and the parameters considered, taking into account both cost and time complexity. The sensing properties of MXene derivatives are then comprehensively reviewed, categorized by their types (M₂X, M₃X₂, M₄X₃), and are discussed in terms of material properties, sensitivity, selectivity, and response time, amongst others. Furthermore, the prospects for these sensors are examined, focusing on their potential applications. Lastly, the review highlights future opportunities for theoretical research and the application of MXene materials in the development of cutting-edge devices. By presenting an overview of theoretical research and recent advancements, this review aims to provide valuable insights into this burgeoning field and pave the way for new avenues in gas detection research.</p></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"6 ","pages":"Article 100174"},"PeriodicalIF":5.9,"publicationDate":"2023-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666053923000371/pdfft?md5=5c9338f8d88d7a516a2c76b270aaf033&pid=1-s2.0-S2666053923000371-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46501891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}