Sensors and Actuators Reports最新文献

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Nanocrystalline ZnO quantum dot-based chemiresistive gas sensors: Improving sensing performance towards NO2 and H2S by optimizing operating temperature 基于纳米晶ZnO量子点的化学电阻气体传感器:通过优化工作温度提高对NO2和H2S的传感性能
IF 5.9
Sensors and Actuators Reports Pub Date : 2023-06-03 DOI: 10.1016/j.snr.2023.100166
Dung Thi Hanh To , Ji Young Park , Bingxin Yang , Nosang V. Myung , Yong-Ho Choa
{"title":"Nanocrystalline ZnO quantum dot-based chemiresistive gas sensors: Improving sensing performance towards NO2 and H2S by optimizing operating temperature","authors":"Dung Thi Hanh To ,&nbsp;Ji Young Park ,&nbsp;Bingxin Yang ,&nbsp;Nosang V. Myung ,&nbsp;Yong-Ho Choa","doi":"10.1016/j.snr.2023.100166","DOIUrl":"https://doi.org/10.1016/j.snr.2023.100166","url":null,"abstract":"<div><p>Nanocrystalline ZnO quantum dots (QD) with a diameter of 10 nm was synthesized and tested toward eight different toxic industrial chemicals (<em>i.e.,</em> nitrogen dioxide (NO<sub>2</sub>), hydrogen sulfide (H<sub>2</sub>S), ammonia (NH<sub>3</sub>), carbon monoxide (CO), methane (CH<sub>4</sub>), ethanol (C<sub>2</sub>H<sub>5</sub>OH), acetone (CH<sub>3</sub>)<sub>2</sub>CO, and toluene (C<sub>6</sub>H<sub>5</sub>CH<sub>3</sub>)) with a broad concentration range at five different operating temperatures. Systemic studies allow to determine the kinetics of gas sensing as well as the competing reactions of analytes with sensing material and adsorbed oxygen. ZnO QD showed an excellent sensing performance toward NO<sub>2</sub> and H<sub>2</sub>S in comparison to other target analytes. The selectivity can be further improved by controlling the operating temperature (<em>i.e.,</em> higher selectivity toward NO<sub>2</sub> and H<sub>2</sub>S were achieved at 300 °C and 450 °C, respectively). Moreover, the optimal temperature was found to be analyte dependent.</p></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"6 ","pages":"Article 100166"},"PeriodicalIF":5.9,"publicationDate":"2023-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"2892069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Nanosensor platforms for detection of milk adulterants 牛奶掺假物检测的纳米传感器平台
IF 5.9
Sensors and Actuators Reports Pub Date : 2023-06-01 DOI: 10.1016/j.snr.2023.100159
Himshweta , Minni Singh
{"title":"Nanosensor platforms for detection of milk adulterants","authors":"Himshweta ,&nbsp;Minni Singh","doi":"10.1016/j.snr.2023.100159","DOIUrl":"https://doi.org/10.1016/j.snr.2023.100159","url":null,"abstract":"<div><p>Milk is a substrate for adulteration, and it is crucial to identify adulterants, and their quantities in milk products. In order to safeguard consumers from fake products and health risks, authenticity of milk products is in high demand. Analytical tools that are comprehensive, quick, and sensitive are necessary to monitor milk quality and screen for any undesirable substances. The traditional methods for the detection of adulterants in milk products are experiencing more difficulties due to their poor selectivity, sensitivity, and unsuitability for complex matrices. The researchers are paying close attention to nanomaterial based sensing systems, which are seen to be among the most effective alternatives to the traditional approaches. This review focuses on optical and electrochemical nanosensors including mechanisms and performances, in relation to their benefits, drawbacks, and applicability to milk products. It also addresses new developments in the field of nanoemsembles platforms for the rapid detection of adulterants in dairy products. A section of particular interest is the detection of milk authenticity, as it is known that milk from different animal species are intermixed.</p></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"5 ","pages":"Article 100159"},"PeriodicalIF":5.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"2378382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Design and development of a novel colorimetric assay and a portable optical system for the detection of aminoglycoside antibiotics 氨基糖苷类抗生素的新型比色测定和便携式光学系统的设计与开发
IF 5.9
Sensors and Actuators Reports Pub Date : 2023-06-01 DOI: 10.1016/j.snr.2023.100151
Navya Sethu, Sreya Krishnakumar, Veena Mitra, Chandrakant Tagad, Renu Vyas
{"title":"Design and development of a novel colorimetric assay and a portable optical system for the detection of aminoglycoside antibiotics","authors":"Navya Sethu,&nbsp;Sreya Krishnakumar,&nbsp;Veena Mitra,&nbsp;Chandrakant Tagad,&nbsp;Renu Vyas","doi":"10.1016/j.snr.2023.100151","DOIUrl":"https://doi.org/10.1016/j.snr.2023.100151","url":null,"abstract":"<div><p>In recent years, environmental contamination with antibiotics has become a severe threat to humankind requiring urgent attention. Presence of incompletely metabolized antibiotics in water bodies, leads to their entry into food chain via live stock and serve as a severe threat to human health. Hence it is imperative that the antibiotics are detected at the source itself. Aminoglycosides are broad spectrum antibiotics known to be more toxic and resistant to multidrug resistant (MDR) organisms compared to other classes of antibiotics. Accordingly in the present work a selective, sensitive and low-cost detection technique for aminoglycoside based antibiotics has been developed. An iron-dependent lipid peroxidation has been explored for the first time to develop a rapid and sensitive colorimetric assay for detecting aminoglycoside antibiotics. A lab-on-chip model (LoC) was designed and developed to miniaturize the colorimetric assay based model for its applications in the real-time analysis of antibiotics. The LoC was integrated with optical fibers, electronic components and associated signal processing circuitry to construct a portable device for antibiotic quantification. Interestingly a selective response towards gentamicin amongst the tested antibiotic was observed. The formation of a colored product within five minutes of reaction time enables a swift and less cumbersome analysis and compared to existing sophisticated analytical techniques. The detection method was validated for gentamicin spiked environmental samples and showed a recovery of more than 90%. This method can serve as a suitable alternative in limited laboratory setups and provides a generic platform for developing a rapid, user-friendly and economical detection methods for environmental monitoring of antibiotics.</p></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"5 ","pages":"Article 100151"},"PeriodicalIF":5.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"2378380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Cationic cellulose Nanofibrils-based electro-actuators: The effects of counteranion and electrolyte 基于阳离子纤维素纳米纤维的电动执行器:反阴离子和电解质的影响
IF 5.9
Sensors and Actuators Reports Pub Date : 2023-06-01 DOI: 10.1016/j.snr.2023.100142
Frédéric Héraly, Bo Pang, Jiayin Yuan
{"title":"Cationic cellulose Nanofibrils-based electro-actuators: The effects of counteranion and electrolyte","authors":"Frédéric Héraly,&nbsp;Bo Pang,&nbsp;Jiayin Yuan","doi":"10.1016/j.snr.2023.100142","DOIUrl":"https://doi.org/10.1016/j.snr.2023.100142","url":null,"abstract":"<div><p>Cellulose-based electro-actuators have enormous potential in various applications, <em>e.g.</em> artificial muscles, soft grippers, medical devices, just to name a few, owing to their high mechanical strength, lightness and natural abundance. However, significant challenges remain in the fabrication of such electro-actuators featuring low operating voltage and fast response kinetics. We report here a facile fabrication route towards high-performance electro-actuators composed of CNFs films doped with ionic liquids or lithium salts and sandwiched by two thin film gold electrodes. Large bending motion at voltages as low as 3.0 V could be observed. The size effect of both anions and cations on the actuation was comprehensively investigated. CNF-TFSI@LiTFSI and CNF-BF<sub>4</sub>@EMIM-BF<sub>4</sub> electro-actuators presented the best bending strain under an AC voltage of 3.0 V. This work provides new inspiration in the design of natural polymer-based high-performance electro-actuators.</p></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"5 ","pages":"Article 100142"},"PeriodicalIF":5.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"3209073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Wearable graphene-based fabric electrodes for enhanced and long-term biosignal detection 用于增强和长期生物信号检测的可穿戴石墨烯织物电极
IF 5.9
Sensors and Actuators Reports Pub Date : 2023-06-01 DOI: 10.1016/j.snr.2023.100161
Babar Ali , Hossein Cheraghi Bidsorkhi , Alessandro G. D'Aloia , Marco Laracca , Maria S. Sarto
{"title":"Wearable graphene-based fabric electrodes for enhanced and long-term biosignal detection","authors":"Babar Ali ,&nbsp;Hossein Cheraghi Bidsorkhi ,&nbsp;Alessandro G. D'Aloia ,&nbsp;Marco Laracca ,&nbsp;Maria S. Sarto","doi":"10.1016/j.snr.2023.100161","DOIUrl":"https://doi.org/10.1016/j.snr.2023.100161","url":null,"abstract":"<div><p>Wearable health sensing devices are crucial and the development of multi-sensing textiles for non-invasive and continuous long-term biosignal monitoring is of primary interest. Nowadays, different wearable sensors are available but they usually lack comfort for continuous use during normal daily life activities. In this study, new graphene-based flexible dry electrodes are investigated to overcome the limitations of the currently available electrodes. Briefly, they are realized through casting PVDF (polyvinylidene fluoride)/GNP (graphene nanoplatelets) nanocomposite over commercial textiles. These electrodes are soft and flexible and adhere more easily to the skin. In terms of performance, the PVDF/GNP electrodes show lower impedance per unit area compared to commercial ones, hence they can be employed for biosignal detection. In particular, the developed electrodes are used for electrocardiogram (ECG) signal monitoring. The recorded ECG signal-to-noise ratio (SNR) reached up to 40 dB and all necessary ECG signal features and intervals are clearly distinguishable. Furthermore, the essential ECG signal intervals on each cadiac cycle show very small variations in time. Finally, the superhydrophobic property allows the electrodes to be used repeatedly after washing. As a final note, the developed dry PVDF/GNP electrodes provide reusability, biocompatibility, good skin-electrode contact, and no signs of skin irritation.</p></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"5 ","pages":"Article 100161"},"PeriodicalIF":5.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"2892072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Highly efficient non-enzymatic electrochemical glucose sensor based on carbon nanotubes functionalized by molybdenum disulfide and decorated with nickel nanoparticles (GCE/CNT/MoS2/NiNPs) 基于二硫化钼功能化碳纳米管和纳米镍修饰(GCE/CNT/MoS2/NiNPs)的高效无酶电化学葡萄糖传感器
IF 5.9
Sensors and Actuators Reports Pub Date : 2023-06-01 DOI: 10.1016/j.snr.2022.100136
Balla Fall , Diébel Dado Sall , Miryana Hémadi , Abdou Karim Diagne Diaw , Modou Fall , Hyacinthe Randriamahazaka , Sabu Thomas
{"title":"Highly efficient non-enzymatic electrochemical glucose sensor based on carbon nanotubes functionalized by molybdenum disulfide and decorated with nickel nanoparticles (GCE/CNT/MoS2/NiNPs)","authors":"Balla Fall ,&nbsp;Diébel Dado Sall ,&nbsp;Miryana Hémadi ,&nbsp;Abdou Karim Diagne Diaw ,&nbsp;Modou Fall ,&nbsp;Hyacinthe Randriamahazaka ,&nbsp;Sabu Thomas","doi":"10.1016/j.snr.2022.100136","DOIUrl":"https://doi.org/10.1016/j.snr.2022.100136","url":null,"abstract":"<div><p>Glucose detection using sensing materials has lately received interest due to the increased demand for sensitive and selective glucose sensors in pharmaceutical, clinical, and industrial settings. Carbon nanotubes (CNTs) are used intensively as a specific class of effective electrode substances in electrochemical sensing due to their large surface area and interesting physical and electrochemical characteristics. Nickel is an attractive transition metal for glucose electrooxidation with high catalytic activity. In this study, CNT/MoS<sub>2</sub>/NiNPs nanocomposites with different CNT/MoS<sub>2</sub> ratios have been prepared by a hydrothermal reaction. The CNT/MoS<sub>2</sub> nanocomposites were characterized by X-ray diffraction (XRD), Raman spectroscopy and Fourier transform infrared spectroscopy (FTIR), and their morphology and composition were characterized by field emission scanning electron microscopy (FESEM). Electrocatalytic activity of the as-prepared nanomaterials towards glucose oxidation was investigated by cyclic voltammetry and amperometry in alkaline media. An excellent sensitivity value of 1212 μA·mM<sup>−1</sup>·cm<sup>−2</sup> with a wide linear range (0.05–0.65 mM), a low detection threshold of 0.197 μM and a short response time (3 s) were achieved by the hybrid CNT/MoS<sub>2</sub>/NiNPs sensor. Its superior catalytic activity and low cost make this hybrid very promising for applications in the direct sensing of glucose.</p></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"5 ","pages":"Article 100136"},"PeriodicalIF":5.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"1629258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
Lychee-like SnO2 hollow microspheres sensitized by carbon quantum dots for high-sensitivity ethanol sensor 碳量子点敏化荔枝样SnO2空心微球用于高灵敏度乙醇传感器
IF 5.9
Sensors and Actuators Reports Pub Date : 2023-06-01 DOI: 10.1016/j.snr.2023.100157
Zhenyu Yuan, Yongchen Sui, Meige Ding, Hongmin Zhu
{"title":"Lychee-like SnO2 hollow microspheres sensitized by carbon quantum dots for high-sensitivity ethanol sensor","authors":"Zhenyu Yuan,&nbsp;Yongchen Sui,&nbsp;Meige Ding,&nbsp;Hongmin Zhu","doi":"10.1016/j.snr.2023.100157","DOIUrl":"https://doi.org/10.1016/j.snr.2023.100157","url":null,"abstract":"<div><p>In this work, the application of carbon quantum dots as known as CQDs for ethanol detection is pioneered, and a multi-fold improvement in gas sensor performance is achieved through the unique electron transport mechanism of carbon quantum dots. The lychee-like SnO<sub>2</sub> hollow microspheres and CQDs are prepared by a solvent heat method. The composites are assembled by rapid grinding, ultrasonication, and stirring. The minimum detection limit is 500 ppb. The response/recovery time of the best mass percentage composite is 9 s/16 s to ethanol at 100 ppm with an optimum working temperature of 216℃ in the target gas-sensitive test. Such a fast response speed improvement is ascribed to the excellent electron transfer efficiency of the 5 nm diameter carbon quantum dots (CQDs).</p></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"5 ","pages":"Article 100157"},"PeriodicalIF":5.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"1629265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Amperometric sensor for gaseous H2O2 based on copper redox mediator incorporated electrolyte 基于铜氧化还原介质外加电解质的气态H2O2安培传感器
IF 5.9
Sensors and Actuators Reports Pub Date : 2023-06-01 DOI: 10.1016/j.snr.2023.100144
Urša Klun , David Zorko , Leon Stojanov , Valentin Mirčeski , Vasko Jovanovski
{"title":"Amperometric sensor for gaseous H2O2 based on copper redox mediator incorporated electrolyte","authors":"Urša Klun ,&nbsp;David Zorko ,&nbsp;Leon Stojanov ,&nbsp;Valentin Mirčeski ,&nbsp;Vasko Jovanovski","doi":"10.1016/j.snr.2023.100144","DOIUrl":"https://doi.org/10.1016/j.snr.2023.100144","url":null,"abstract":"<div><p>The determination of gases and other volatile compounds using electrochemical gas sensors remains a challenge with respect to sensitivity and selectivity. Many real-life situations require fast, sensitive, and yet easy-to-operate sensors for gaseous hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>) that can operate at room temperature. Herein, we present an H<sub>2</sub>O<sub>2</sub> gas sensor comprising a polyacrylic acid and NaOH gel electrolyte that included Cu(II) ions acting as a redox mediator and commercially available screen-printed carbon electrodes. Aqueous polyacrylate gel electrolyte containing Cu(II) provided for sensing material that enabled the accumulation and stabilization of the gaseous analyte and via redox interaction with Cu(II) its fast and sensitive detection. The designed sensor exhibited good sensitivity in the low mg m<sup>−3</sup> range with a wide linear response in the examined concentration range of 10–100 mg m<sup>−3</sup> and a rapid detection after only 2 min accumulation under ambient conditions. Sensor's relatively simple setup and solid electroanalytical performance have strong application potential in emerging fields such as clinical diagnostics, explosive detection, environmental monitoring and occupational health and safety.</p></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"5 ","pages":"Article 100144"},"PeriodicalIF":5.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"2378379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Development of interdigitated electrode based enzyme sensor for triglyceride monitoring using engineered oxygen insensitive glycerol 3-phosphate oxidase 利用工程氧不敏感甘油3-磷酸氧化酶进行甘油三酯监测的交叉电极酶传感器的研制
IF 5.9
Sensors and Actuators Reports Pub Date : 2023-06-01 DOI: 10.1016/j.snr.2023.100164
Inyoung Lee , Sheng Tong , Mika Hatada , Adrianna Masterson , Kentaro Hiraka , Junko Okuda-Shimazaki , Wakako Tsugawa , Gary Hughes , Koji Sode
{"title":"Development of interdigitated electrode based enzyme sensor for triglyceride monitoring using engineered oxygen insensitive glycerol 3-phosphate oxidase","authors":"Inyoung Lee ,&nbsp;Sheng Tong ,&nbsp;Mika Hatada ,&nbsp;Adrianna Masterson ,&nbsp;Kentaro Hiraka ,&nbsp;Junko Okuda-Shimazaki ,&nbsp;Wakako Tsugawa ,&nbsp;Gary Hughes ,&nbsp;Koji Sode","doi":"10.1016/j.snr.2023.100164","DOIUrl":"https://doi.org/10.1016/j.snr.2023.100164","url":null,"abstract":"<div><p>Triglycerides (TG) are an important biomarker of various diseases including hyper-lipidemia. Current emergent requirements for TG sensing include the development of electrochemical sensors for easy, cost-effective, disposable and single use triglyceride sensors. We propose a TG sensor using an engineered glycerol 3-phosphate oxidase (GlpO) and electrochemical detection. In this study, we aimed to develop an electrochemical TG sensor based on engineering the oxidative half reaction of GlpO to be oxygen insensitive, with the employment of an interdigitated electrode (IDE). To construct an oxygen insensitive mutant GlpO, we constructed a double mutant, Met104Phe/Asp169Glu, which revealed an engineered GlpO exhibiting repressed oxidase activity, while its dye-mediated dehydrogenase activity enhanced. The electrochemical enzyme sensor was constructed for the measurement of TG based on engineered GlpO using disposable screen-printed carbon electrode (SPCE) or disposable IDE using Ru complex as the electron mediator. By using the disposable IDE sensor, a highly sensitive electrochemical sensor for Glp was achieved, with the sensitivity of 0.4 µA/mM. The improved sensitivity was 2.4 times higher than that of SPCE (0.17 µA/mM), with LOD of 0.022 mM. Furthermore, the dry sensor strip, where the double mutant GlpO and Ru complex were dropcasted and dried on the IDE, was prepared and the Glp concentration was successfully measured in the delipidized serum solution. Therefore, by the employment of the established pretreatment method for TG to release Glp, a highly sensitive, accurate, easy and rapid electrochemical measurement method for TG will be developed using constructed M104F/D169E mutant GlpO with the combination of IDE.</p></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"5 ","pages":"Article 100164"},"PeriodicalIF":5.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"3209850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhanced response and selective gold nanoparticles/carbon nanotubes biosensor for the early detection of HER2 biomarker 增强响应和选择性金纳米颗粒/碳纳米管生物传感器用于HER2生物标志物的早期检测
IF 5.9
Sensors and Actuators Reports Pub Date : 2023-06-01 DOI: 10.1016/j.snr.2023.100158
Yahia Makableh , Tamara Athamneh , Manar Ajlouni , Sara Hijazi , Aseel Alnaimi
{"title":"Enhanced response and selective gold nanoparticles/carbon nanotubes biosensor for the early detection of HER2 biomarker","authors":"Yahia Makableh ,&nbsp;Tamara Athamneh ,&nbsp;Manar Ajlouni ,&nbsp;Sara Hijazi ,&nbsp;Aseel Alnaimi","doi":"10.1016/j.snr.2023.100158","DOIUrl":"https://doi.org/10.1016/j.snr.2023.100158","url":null,"abstract":"<div><p>A screen-printed carbon electrode was used to develop a biosensor with an improved response and selectivity for detecting human epidermal growth factor receptor 2 (HER2). To investigate the performance of the biosensor, electrochemical characterizations such as impedance spectroscopy, differential pulse and cyclic voltammetry were used, in addition to Fourier transform infrared spectroscopy and atomic force microscopy. The biosensor responds in a quick manner, taking only 5 min to bind to the target protein. Furthermore, the results show that the nano-biosensor has a detection limit of 4.4 Pg/ml. The findings suggest that the biosensor can be used as a potential analytical tool for HER2 detection, particularly at low concentrations, which can be a tool used in the early detection of breast cancer.</p></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"5 ","pages":"Article 100158"},"PeriodicalIF":5.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"2378381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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