Results in Chemistry最新文献

{"title":"Computational identification of anti-cancer compounds targeting the RNA-binding domain of human FOX-1 protein (RBFOX1)","authors":"Muhammad Tahir ul Qamar ,&nbsp;Pablo Sanz-Jimenez ,&nbsp;Shaima Rabeea Banoon ,&nbsp;Xi-Tong Zhu ,&nbsp;Fahad M. Aldakheel ,&nbsp;Nahlah Makki Almansour ,&nbsp;Leen A. Aldaiji ,&nbsp;Wafa Abdullah I. Al-Megrin ,&nbsp;Faisal Ahmad","doi":"10.1016/j.rechem.2024.102004","DOIUrl":"10.1016/j.rechem.2024.102004","url":null,"abstract":"<div><div>The transcription factor RBFOX1 is essential for cellular proliferation and has shown upregulation in many human cancers. The overexpression of this gene correlates with the motility of cancer cells, their ability to invade surrounding tissues. The aforementioned processes are pivotal in cancer progression, making RBFOX1 a significant target for innovative cancer therapies. The present study seeks to identify new inhibitor compounds that obstruct the biological processes of the target protein associated with cancer. Results shows that control (3S,5aS,6R,8aS,9R,10S,12R,12aS)-3,6,9-trimethyldecahydro-3H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-ol (artenimol) reflecting the binding affinities of −7.9 kcal/mol, Top1 (4-[[2-butyl-5-[(E)-2-carboxy-3-thiophen-2-ylprop-1-enyl]imidazol-1-yl]methyl]benzoic acid) shows −8.7 kcal/mol and Top2 (R)-1-carboxy-5-((S)-2-((2R,4S)-4-carboxy-5,5-dimethylthiazolidin-2-yl)-2-(2-phenylacetamido)acetamido)pentan-1-aminium indicating −8.2 k cal/mol. Additional, molecular dynamic simulation studies shows significant stability during RMSD and RMSF analyses over a 100 ns timescale. Binding domain residues i.e. Phe52, Arg10, Thr84, Ala85 and Arg86 has demonstrated the stability of the system due to robust hydrogen bonds. All of the top hit inhibitor exhibited more stability in comparison to the control inhibitor, where it penetrated deeply, as depicted in PCA analysis. Binding energies and Waterswap calculations significantly refines our comprehensive simulation model. Consequently, our findings provide a potential framework for researchers to further explore in vivo and in vitro analyses of inhibitors targeting the HBFOX1 gene, representing a potential advancement in cancer treatment.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"13 ","pages":"Article 102004"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143169299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimization extraction process of Shenghua Decoction and evaluation of its analgesic effects","authors":"Zhonghui Pu ,&nbsp;Lijuan Chen ,&nbsp;Huaidan Liu ,&nbsp;Jingzhu Deng ,&nbsp;Li Li ,&nbsp;Liang Xiong ,&nbsp;Liuying Li","doi":"10.1016/j.rechem.2024.102017","DOIUrl":"10.1016/j.rechem.2024.102017","url":null,"abstract":"<div><div>Shenghua Decoction (SHD) is a very famous formula that has been used for treating postpartum diseases in China. However, there has been no study published, to date, reporting the preparation process and analgesic effects of SHD. This study aimed to optimize the high-content SHD production process and investigate its analgesic activity. Taking the content of ferulic acid and senkyunolide I determined by HPLC as indexes, the effect on SHD of several extraction processing variables, including liquid–solid ratio, soaking time, decocting time and ethanol precipitation concentration, had been examined by using Box-Behnken design (BBD) with three levels and four factors were adopted for optimizing SHD extraction process, and the optimized conditions were further validated. The analgesic activity of SHD was assessed, based on mouse pain response to hot plate and intraperitoneally injected acetic acid. The optimized values of SHD extraction process variables were found to be 40 mL/g of liquid–solid ratio, 2 h of soaking time, 1.5 h of decocting time, 70 % of ethanol precipitation concentration. The optimum conditions led to maximal combined content of ferulic acid and senkyunolide I at 1.2336 mg/g averaged from three validation tests (<em>RSD</em> = 1.84 %, n = 3), 0.9347 mg/g for ferulic acid and 0.2989 mg/g for senkyunolide I, and the bias ratio was 1.82 % compared with the predicted value of 1.251 mg/g, indicating the experimental values obtained from the BBD model agreed with that of the predicted values.</div><div>Analgesic activity results indicated that SHD at all doses significantly reduced the number of twists induced by glacial acetic acid dose-dependently, and prolonged latency of foot licking to varying degrees at every stage of mice hot-plate test. This study not only developed a rapid and sensitive process that was successfully utilized for extracting SHD, but also discovered SHD with analgesic activity, which provided helpful information for further study.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"13 ","pages":"Article 102017"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143169605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Visible light photocatalytic degradation of tetracycline using copper ferrite nanoparticles synthesized via Glycine-Assisted combustion method","authors":"A. Dinesh ,&nbsp;K. Radhakrishnan ,&nbsp;V. Renuga ,&nbsp;Rajendra P. Patil ,&nbsp;Suriyaprakash Rajadesingu ,&nbsp;S. Suthakaran ,&nbsp;L. Guganathan ,&nbsp;Manikandan Ayyar ,&nbsp;Madhappan Santhamoorthy ,&nbsp;Lalitha Gnanasekaran ,&nbsp;Munawar Iqbal","doi":"10.1016/j.rechem.2025.102037","DOIUrl":"10.1016/j.rechem.2025.102037","url":null,"abstract":"<div><div>Copper Ferrite (CuFe₂O₄) nanoparticles (NPs) were synthesized by the combustion-assisted method using glycine as a fuel to evaluate their photocatalytic degradation efficiency for tetracycline (TC) under visible light. Several analytical methods were used to confirm the synthesized CuFe₂O₄ NPs. X-ray diffraction (XRD) was used to check the phase’s structure and purity, FT-IR was used to find out what functional groups were present, UV–Vis diffuse reflectance spectroscopy (DRS) was used to look at the optical properties, and scanning electron microscopy (SEM) was used to see the structure’s shape. These results confirm the formation of highly crystalline CuFe₂O₄ NPs. The photocatalytic degradation of TC was studied using visible light and the effect of parameters such as the concentration of the catalyst (0.5 g/L to 2.5 g/L), initial TC concentration (10– 50 mg/L) and irradiation time (30–150 min). The degradation efficiency reached a maximum value of 95.8 % for a 150 min irradiation under the optimum condition of the photocatalytic activity was further raised by 25 % by the addition of hydrogen peroxide (H₂O₂). The CuFe₂O₄ NPs had rather high recyclability after the photocatalytic process, they had 90 % of their initial activity, which was tested after the fifth run. This study shows that green synthesized CuFe₂O₄ NPs are potentially useful as reusable visible-light photocatalysts for breaking down drugs, specifically tetracycline, through oxidation in water.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"13 ","pages":"Article 102037"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143169606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deciphering the role of flutamide, fluorouracil, and furomollugin based ionic liquids in potent anticancer agents: Quantum chemical, medicinal, molecular docking and MD simulation studies","authors":"Danish Ali ,&nbsp;Muhammad Arif Ali ,&nbsp;Muhammad Sarfraz ,&nbsp;Afifa Yousuf ,&nbsp;Rasham Zulfiqar ,&nbsp;Abdul Rauf ,&nbsp;Hong-Liang Xu ,&nbsp;Muhammad Arshad","doi":"10.1016/j.rechem.2025.102029","DOIUrl":"10.1016/j.rechem.2025.102029","url":null,"abstract":"&lt;div&gt;&lt;div&gt;Ionic liquids (ILs) have emerged as a versatile candidate in medicinal chemistry, electrochemistry catalysis, and biotechnology. In this work, we explored the electronic interionic interactions, stability, and reactivity of FDA approved drug-based cations flutamide &lt;strong&gt;([FT1]&lt;sup&gt;+&lt;/sup&gt;&lt;/strong&gt;, &lt;strong&gt;[FT2]&lt;sup&gt;+&lt;/sup&gt;)&lt;/strong&gt;, fluorouracil &lt;strong&gt;([FU1]&lt;sup&gt;+&lt;/sup&gt;)&lt;/strong&gt;, and furomollugin &lt;strong&gt;([FM1]&lt;sup&gt;+&lt;/sup&gt;&lt;/strong&gt;, &lt;strong&gt;[FM2]&lt;sup&gt;+&lt;/sup&gt;)&lt;/strong&gt;, paired with amino acid &lt;strong&gt;[NH]&lt;sup&gt;−&lt;/sup&gt;&lt;/strong&gt;, nitrate &lt;strong&gt;[NO&lt;sub&gt;3&lt;/sub&gt;]&lt;sup&gt;−&lt;/sup&gt;&lt;/strong&gt;, and triflate &lt;strong&gt;[CF&lt;sub&gt;3&lt;/sub&gt;]&lt;sup&gt;−&lt;/sup&gt;&lt;/strong&gt; anions, in gas and solvent phases (benzene and water). Frontiers molecular orbitals (FMOs) showed that &lt;strong&gt;[FT1]&lt;sup&gt;+&lt;/sup&gt;[NH]&lt;sup&gt;–&lt;/sup&gt;&lt;/strong&gt; exhibits the smaller &lt;em&gt;E&lt;/em&gt;&lt;sub&gt;gap&lt;/sub&gt; on both gas and solvent phase from 5.24 to 4.39 eV, suggesting high reactivity and increasing solubility. Notably, the IL pair &lt;strong&gt;[FT1]&lt;sup&gt;+&lt;/sup&gt;[NH]&lt;sup&gt;–&lt;/sup&gt;&lt;/strong&gt; possessed substantial interaction energies in the gas phase (−426.64 kcal/mol), in benzene (−390.24 kcal/mol), and in water (−369.69 kcal/mol), highlighting its potential to disrupt cancer cell growth and exhibit strong anticancer efficacy. The stability of &lt;strong&gt;[FT1]&lt;sup&gt;+&lt;/sup&gt;[NH]&lt;sup&gt;–&lt;/sup&gt;&lt;/strong&gt; was further corroborated by significant Gibbs free energy and enthalpy values (−545.30 and −560.36 kcal/mol). Bioinformatics studies reveal that our studied ILs possess superior drug-likeness along with supportive medicinal chemistry parameters. Such as, toxicity evaluation based on the TOX21 pathway confirmed the non-toxic attributes of these ILs, bolstering their potential as antitumor drugs. The metabolic prediction for &lt;strong&gt;[FM1]&lt;sup&gt;+&lt;/sup&gt;&lt;/strong&gt; was consistent with its expected behavior in the biological system with its likelihood ranging from 89 % to 83 %. Additionally, &lt;em&gt;in silico&lt;/em&gt; docking investigations against the protein (PDB ID: 1B38) showed that all designed ligands &lt;strong&gt;[FT1]&lt;sup&gt;+&lt;/sup&gt;&lt;/strong&gt;, &lt;strong&gt;[FT2]&lt;sup&gt;+&lt;/sup&gt;&lt;/strong&gt;, &lt;strong&gt;[FU1]&lt;sup&gt;+&lt;/sup&gt;&lt;/strong&gt;, &lt;strong&gt;[FM1]&lt;sup&gt;+&lt;/sup&gt;&lt;/strong&gt;, and &lt;strong&gt;[FM2]&lt;sup&gt;+&lt;/sup&gt;&lt;/strong&gt; display binding affinities values of −7.82, −6.30, −6.09, −5.86, and −7.72 kcal/mol superior to both the reference and reported drug fluorouracil. Molecular dynamics (MD) simulation reinforced the docking results by utilizing root mean square deviation (RMSD) values of &lt;strong&gt;[FT1]&lt;sup&gt;+&lt;/sup&gt;&lt;/strong&gt; varies from 0.147387 to 0.539310 Å and &lt;strong&gt;[FM2]&lt;sup&gt;+&lt;/sup&gt;&lt;/strong&gt; lies between 0.138098 Å and 0.583763 Å and root means square fluctuation (RMSF) values for &lt;strong&gt;[FT1]&lt;sup&gt;+&lt;/sup&gt;&lt;/strong&gt; was 0.069428–0.298235Å and &lt;strong&gt;[FM2]&lt;sup&gt;+&lt;/sup&gt;&lt;/strong&gt; 0.070097–0.364413Å provides insight into stability and the time-dependent atomic deviations. In addition, Ramachandran plots indicate that &gt;90 % of residues occupy the favored regions supporting t","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"13 ","pages":"Article 102029"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143169639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Removal of U(VI) by Micrococcus aloeverae: condition, kinetic and mechanism studies","authors":"Xingming Gao ,&nbsp;Mengmei Ye ,&nbsp;Wenxin Li ,&nbsp;Yong Lu ,&nbsp;Lingzhi Bao","doi":"10.1016/j.rechem.2025.102019","DOIUrl":"10.1016/j.rechem.2025.102019","url":null,"abstract":"<div><div>The ecological and environmental implications arising from the release of uranium during nuclear industry and mining activities are subject to considerable apprehension. Employing microbial agents for uranium remediation offers a promising and efficient alternative to tackle soil or wastewater contamination caused by uranium. In this work, we successfully isolated and identified a highly uranium-tolerant strain GX01, identified as <em>Micrococcus aloeverae</em>, from soil samples collected at a uranium mining site. The state, kinetics and mechanism of U(VI) removal by <em>Micrococcus aloeverae</em> were then investigated. The strain demonstrated both biotransformation and biosorption ability to U(VI), with an excellent removal capacity of 123 mg/g for U(VI) at pH 6.0. The involvement of carboxyl, amide, and amine groups in the biosorption processes was determined by Fourier transform infrared spectroscopy (FTIR) and X-ray photoelectron spectroscopy (XPS) analysis. Kinetic and isothermal studies demonstrated that the biosorption of U(VI) by <em>Micrococcus aloeverae</em> followed a pseudo-second order mode and Langmuir model. These results initially established <em>Micrococcus aloeverae</em> as an idea candidate for radionuclide removal.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"13 ","pages":"Article 102019"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143169649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Green synthesis of silver and gold nanoparticles using quercetin extracted from Arctium lappa by HPLC, Characterization and Estimation of antioxidant activity","authors":"Mahmood Zaki Lafta ,&nbsp;Rafah Razooq Hameed Al-Samarrai ,&nbsp;Mohamed Bouaziz","doi":"10.1016/j.rechem.2025.102028","DOIUrl":"10.1016/j.rechem.2025.102028","url":null,"abstract":"<div><div>Arctium lappa is a therapeutic plant high in bioactive components, including flavonoids, which have antioxidant, anti-inflammatory, and antibacterial effects. Quercetin, a major flavonoid, is recognized for its pharmacological properties. The purpose of this study was to extract quercetin from A. lappa and use it for the green synthesis of gold (AuNPs) and silver nanoparticles (AgNPs) to evaluate their antioxidant properties. Quercetin was extracted using the Soxhlet method with petroleum ether, chloroform, and methanol. Quercetin was purified using hydrolysis and crystallization before being characterized using HPLC, UV–Vis, FTIR, and NMR methods. Laser ablation was used to synthesize AuNPs and AgNPs, with extracted quercetin acting as a reducing agent. The nanoparticles were examined with SEM, TEM, and XRD. Antioxidant activity was measured using the DPPH free radical scavenging test, and IC50 values were generated to compare to standard ascorbic acid.HPLC indicated that the maximum quantity of quercetin (98.6 %) was achieved using chloroform extraction. AgNPs had a spherical shape via a typical size of 20–40 nm, whereas AuNPs ranged from 80-160 nm. AgNPs had the highest antioxidant capacity (89.59 %), followed by AuNPs (83.32 %) and quercetin (73.22 %). The IC50 values were 100.4 µg/mL, 120.8 µg/mL, and 146.36 µg/mL, respectively.The researchers effectively extracted quercetin from A. lappa and created AuNPs and AgNPs with significant antioxidant characteristics. AgNPs demonstrated superior free radical scavenging activity, indicating their potential use in biomedical applications, notably antioxidant therapy. More research is needed to understand their medicinal potential fully.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"13 ","pages":"Article 102028"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143169688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A superhydrophobic anti-flaming coating with anti-corrosion function for paper-based triboelectric nanogenerator","authors":"Yanfang Meng ,&nbsp;Junqing Zhao ,&nbsp;Wenming He","doi":"10.1016/j.rechem.2024.101983","DOIUrl":"10.1016/j.rechem.2024.101983","url":null,"abstract":"<div><div>As an effective way for energy conversion, triboelectric nanogenerators (TENGs) have aroused great attention. Particularly, the paper-based TENGs have been paid the highest emphasize for their unparalleled merits: flexibility, light weight, low cost, and recyclability under heavily allocated environmental protection. To address drawbacks of paper-based TENG (e.c. susceptible to moisture, inflammability), here, an effective superhydrophobic-flame-resistant coating for superhydrophobic and flame-resistant dual-treated paper-based TENG is, firstly, proposed. This coating was obtained by in-situ addition of fire-retardants (polyhedral methyl-silsesquioxane and ammonium polyphosphate) during the process of sol–gel reaction of two silane precursors: tetraethyl orthosilicate (TEOS) and tridecafluorooctyl triethoxysilane (FAS). This superhydrophobic-flame-resistant coating endowed paper-based TENG with excellent surfacial hydrophobicity (water contact angle above 150°) and flame-resistant properties (limit oxygen index improved by 5% compared with original sample), simultaneously. Meanwhile, the coating also exhibits outstanding anti-permeability towards water (keep WCA last more than 1 h) and resistance towards acidic corrosion. The superhydrophobic-flame-resistant modification renders the obtained TENG to work with conventional properties under humidity environment and fire protection. This paper-based TENG feasibly powers LED and alarm apparatus, demonstrating its plausibility for new approach for advanced energy harvest and conversion.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"13 ","pages":"Article 101983"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143168177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Catalytic pathways for N-arylation of benzimidazoles: A comprehensive review","authors":"Anila Ghulam ,&nbsp;Tooba Jabeen ,&nbsp;Sana Aslam ,&nbsp;Matloob Ahmad ,&nbsp;Magdi E.A. Zaki","doi":"10.1016/j.rechem.2025.102043","DOIUrl":"10.1016/j.rechem.2025.102043","url":null,"abstract":"<div><div>The <em>N</em>-arylated benzimidazoles are important structural motifs in many biologically active compounds. Due to their distinct physicochemical and structural features, they have applications in a wide range of domains, including pharmaceutical chemistry, material sciences, and catalysis. Synthetic chemists have devised a variety of methods to accomplish efficient <em>N</em>-arylation of benzimidazoles. Transition metal-based catalysis has emerged as a key strategy, utilizing metals such as copper (Cu), palladium (Pd), iron (Fe), nickel (Ni), iridium (Ir), and ruthenium (Ru). These catalysts, which are frequently supported by a variety of ligands, allow for the selective and efficient production of <em>N</em>-aryl bonds under a wide range of reaction conditions. Cross-coupling reactions, such as the Chan-Lam, Ullmann, and Buchwald-Hartwig protocols, are commonly used due to their durability and scalability. Metal-free techniques offer ecologically friendly options, and multicomponent reactions provide the benefit of convergent synthesis. Microwave-assisted reactions and photocatalyzed procedures have improved the efficiency, selectivity, and sustainability of <em>N</em>-arylation reactions. The review provides a comprehensive overview of the recent advancements and strategies employed in constructing this important class of heterocyclic compounds, highlighting their versatility and significance.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"13 ","pages":"Article 102043"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143168484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biogenic synthesis of silver nanoparticles/reduced graphene oxide (AgNPs/rGO) mediated Nephelium lappaceum leaf extract as an effective solid acid catalyst for liquid-phase benzene nitration","authors":"Dewi Yuanita Lestari ,&nbsp;Akhmad Syoufian ,&nbsp;Poedji Loekitowati Hariani ,&nbsp;Amalia Kurnia Amin ,&nbsp;Won-Chun Oh ,&nbsp;Aldino Javier Saviola ,&nbsp;Karna Wijaya","doi":"10.1016/j.rechem.2024.102014","DOIUrl":"10.1016/j.rechem.2024.102014","url":null,"abstract":"<div><div>Researchers are increasingly required to adopt green chemistry principles in developing nanomaterials and their applications to support a sustainable chemical industry and contribute to environmental balance. This study presents the green synthesis of AgNPs/rGO nanocomposites using <em>Nephelium lappaceum</em> as both a bio-reductant and a capping agent, alongside their characterization and application as a solid acid catalyst in benzene nitration reactions. Graphene oxide (GO) was synthesized from graphite using a modified Hummers method, and the AgNPs/rGO nanocomposites were prepared via an ex-situ approach. In this process, <em>Nephelium lappaceum</em> leaf extract served to reduce both silver ions and GO to rGO. The results revealed that the silver nanoparticles were spherical, with an average diameter of 6.76 nm, and were uniformly deposited on the reduced graphene oxide (rGO) surface. Catalyst performance tests demonstrated that the synthesized AgNPs E5/rGO catalyst achieved excellent yields and selectivity in converting benzene into nitrobenzene. Furthermore, the catalyst exhibited remarkable reusability, with only a slight decrease in yield after five uses, while maintaining consistent selectivity toward nitrobenzene as an essential and promising chemical intermediate for many derived chemicals.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"13 ","pages":"Article 102014"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143168490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Iodine promoted one-pot synthesis of flavones","authors":"Darvin Jesús Torres Ribón ,&nbsp;Luis Fernando Roa de la Fuente ,&nbsp;Nancy Romero Ceronio ,&nbsp;Oswaldo Hernández Abreu ,&nbsp;Madeleyne Ramos Rivera ,&nbsp;Jorge R. Juárez ,&nbsp;Rosalía Torralba ,&nbsp;Manuel Velasco Ximello ,&nbsp;Quirino Torres Sauret ,&nbsp;Cuauhtémoc Alvarado Sánchez","doi":"10.1016/j.rechem.2024.101968","DOIUrl":"10.1016/j.rechem.2024.101968","url":null,"abstract":"<div><div>A novel <em>one-pot</em> methodology for the synthesis of flavones starting from simple precursors such as 2′-hydroxyacetophenone and benzaldehyde derivatives in pentan-1-ol (a green solvent), without additives, mediated by iodine and with short reaction times (1 h) is described. A scope of 21 products in yields ranging from 28 % to 90 % is presented. Results demonstrated that the yield was enhanced by the use of benzaldehyde derivatives with activating substituents on the <em>para</em>-position.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"13 ","pages":"Article 101968"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143168783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}