Results in Chemistry最新文献

{"title":"Innovative strategies for organophosphorus remediation: Integrating enzymatic decomposition with membrane technologies","authors":"Morteza Mirzaei ,&nbsp;Ramezan Ali Taheri ,&nbsp;Ali Mohammad Latifi ,&nbsp;Majid Abdouss","doi":"10.1016/j.rechem.2025.102298","DOIUrl":"10.1016/j.rechem.2025.102298","url":null,"abstract":"<div><div>Organophosphorus (OP) compounds, widely used in agriculture, pharmaceuticals, and flame retardancy, pose significant environmental and health risks due to their toxicity, particularly neurotoxicity. While enzymatic degradation and membrane technologies have been studied separately for OP remediation, there is a lack of comprehensive research on the synergistic integration of enzyme-based catalysis with membrane systems. This review addresses this gap by analyzing how enzyme immobilization onto membrane supports enhances the efficiency, stability, and reusability of organophosphorus (OP) degradation processes. We compare various enzyme immobilization strategies (adsorption, covalent bonding, crosslinking) and assess their respective benefits and challenges. Additionally, we introduce a new framework aligning membrane-supported enzyme systems with specific OP decomposition challenges, such as enzyme deactivation and improving continuous-flow performance. Furthermore, this review highlights emerging trends, such as the integration of nanostructured materials like metal-organic frameworks (MOFs) and carbon nanotubes (CNTs) into membranes. These hybrid systems enhance catalytic degradation and offer filtration capabilities, providing a dual advantage over free enzymes or powdered nanomaterials. Enzyme-based membranes enhance enzyme stability, reusability, and operational convenience—particularly in continuous-flow systems—while also capturing particulate contaminants. By exploring enzyme–MOF–membrane composites, we propose innovative solutions for OP remediation in civilian and military applications. This work presents innovative perspectives on enzyme-based membrane technologies, offering efficient, scalable, and environmentally sustainable methods for OP detoxification. Future research should focus on developing integrated, real-time monitoring technologies to further enhance the practicality and scalability of these systems.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"15 ","pages":"Article 102298"},"PeriodicalIF":2.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143912822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploration of novel azole-quinoline hybrids as LdNMT inhibitors using in-silico approach; molecular docking, DFT, molecular dynamics simulations, MMGBSA and ADMET","authors":"Firoj Hassan ,&nbsp;Waseem Ahmad Ansari ,&nbsp;Sabahat Yasmeen Sheikh ,&nbsp;Mohammad Faheem Khan ,&nbsp;Tabrez Faruqui ,&nbsp;Iqbal Azad ,&nbsp;Maqsood A. Siddiqui ,&nbsp;Abdulaziz A. Al-Khedhairy ,&nbsp;Abdul Rahman Khan ,&nbsp;Malik Nasibullah","doi":"10.1016/j.rechem.2025.102303","DOIUrl":"10.1016/j.rechem.2025.102303","url":null,"abstract":"<div><div><em>Leishmania donovani</em>, the causative agent of visceral leishmaniasis (VL), is prevalent in Brazil, East Africa, and India. The treatment options for VL are currently limited and are often associated with adverse effects, highlighting the urgent need for the development of safer and more effective therapies. N-myristoyltransferase (NMT) is one of the few genetically proven therapeutic targets for the development of drugs against kinetoplastid parasitic protozoa. In this study, we performed high-throughput virtual screening (HTVS) of designed 108 azole-quinoline hybrid compounds using molecular docking against <em>Ld</em>NMT. The molecular docking results indicated that compounds 47 and 50, two strong inhibitors, had binding energies of −9.02 and −8.13 kcal/mol, compared to control drug (DDD85646), which had a binding energy of −4.38 kcal/mol. Furthermore, these lead compounds were subjected to molecular dynamics (MD) simulations to determine the stability of the ligand with <em>Ld</em>NMT under physiological conditions. Then, the stability of both complexes revalidated through the MMGBSA method that unfolded the free binding energy −100.83 kcal/mol, and −84.31 kcal/mol for compounds 47, and 50 respectively, which delivered reliable binding stability with the protein. Density functional theory (DFT) analysis was used to explore the chemical reactivity of the lead compounds. This study found that most of the compounds adhered to Lipinski's rule of five with minimal violations, and their ADMET properties were within acceptable ranges compared with the standard drug. The <em>in silico</em> results suggested that azole-quinoline hybrid, particularly compounds 47 and 50, could be promising inhibitors of <em>Ld</em>NMT, potentially serving as effective therapeutic agents for VL treatment.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"15 ","pages":"Article 102303"},"PeriodicalIF":2.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143906161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis, characterization and biological activity of binuclear palladium(II) complexes","authors":"Debakanta Tripathy ,&nbsp;Soumya Lipsa Rath ,&nbsp;Niladri Bihari Debata ,&nbsp;Dillip Kumar Chand","doi":"10.1016/j.rechem.2025.102310","DOIUrl":"10.1016/j.rechem.2025.102310","url":null,"abstract":"<div><div>Two <em>N,N,N′,N′</em>-tetramethylethylenediamine (tmeda) protected palladium(II) complexes 1 and 2 were synthesized using two amide functionalized ligands L1 and L2 respectively. Complexes 1 and 2 were characterized by ¹H, ¹³C NMR, H<img>H COSY, C<img>H COSY and ESI-MS. Molecular structures of both the complexes were confirmed by single crystal X-ray diffraction of analogous complexes 1′ and 2′. Molecular packing in the crystal lattice was evaluated using Hirshfeld surface analysis. It was found that the H…H interaction is the major contributor to the molecular packing in complex 1′. However, in complex 2′, O…H/H…O short contact is the major stabilising factor of the crystal lattice. The biological activity of complexes 1′ and 2′ were evaluated using molecular docking tool. Both the complexes were found to interact with MexB protein and complex 2′ having higher binding affinity as evident from the binding energy values.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"15 ","pages":"Article 102310"},"PeriodicalIF":2.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143894867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Harnessing the power of gaillardin: A natural sesquiterpene with anti-ovarian Cancer potential","authors":"Sadegh Rajabi ,&nbsp;Mahboubeh Irani ,&nbsp;Akram Shahhosseini ,&nbsp;Marc Maresca ,&nbsp;Maryam Hamzeloo-Moghadam","doi":"10.1016/j.rechem.2025.102296","DOIUrl":"10.1016/j.rechem.2025.102296","url":null,"abstract":"<div><div>Ovarian cancer is the eighth most frequent cancer and fifth most common cause of death in women in the world. Gaillardin is a sesquiterpene lactone with an anti-tumor effect on different cancers. This study explored the anti-proliferative and pro-apoptotic effect of gaillardin on the ovarian cancer cell line SKOV3. The proliferation level of SKOV3 cells was assayed using the MTT method. Then, IC₅₀ values for the gaillardin treatment of SKOV3 cells were calculated. The apoptotic death-inducing feature of SKOV3 cells following gaillardin treatment was assessed by flow cytometry. The time-PCR method was used to measure the gene transcript amount of apoptosis markers CASP3, CASP8, CASP9, BAX, BCL2, STAT3, and JAK2. The protein levels of the markers mentioned above were semiquantified using western blotting. Gaillardin significantly inhibited the proliferation of SKOV3 cells compared with the controls. Moreover, the gaillardin-treated SKOV3 cells underwent apoptotic cell death in comparison to the untreated cell line. The results of real-time PCR analysis unraveled that gaillardin treatment significantly upregulated the expression of CASP3, CASP8, CASP9, and BAX but downregulated BCL-2 with no influence on the expression levels of STAT3 and JAK2 transcripts. This sesquiterpene had identical effects on the protein expression of caspases, Bax, and Bcl2. However, it downregulated the phosphorylated forms of JAK2 and STAT3 proteins. Our data indicated that gaillardin may act as an anticancer drug to inhibit the proliferation and induce apoptosis in ovarian cancer cells by triggering the intrinsic and extrinsic pathways of apoptosis and the blockage of the JAK/STAT signaling pathway.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"15 ","pages":"Article 102296"},"PeriodicalIF":2.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143891136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Green synthesis of gold nanoparticles supported over the Myrtus communis L extract modified magnetic iron oxide as a novel antibacterial agent","authors":"Mostafa Moradi ,&nbsp;Morteza Rouhani ,&nbsp;Malak Hekmati ,&nbsp;Hojat Veisi ,&nbsp;Davoud Esmaeli","doi":"10.1016/j.rechem.2025.102323","DOIUrl":"10.1016/j.rechem.2025.102323","url":null,"abstract":"<div><div><em>Myrtus communis</em> L extract, as an herbal substance with carbonyl and phenolic hydroxyl functional groups, can be applied to functionalize the surface of Fe₃O₄ nanoparticles (NPs). In addition, it can enhance the surface characteristics of the magnetite core for anchoring and reduction of gold ions via complexation in an aqueous medium. Then, Fe₃O₄@ <em>Myrtus communis</em> extract was able to reduce, stabilize, and adhere to gold nanoparticles (Au NPs) to fabricate a new magnetic gold nanocomposite. The morphological, structural, and physicochemical properties of the samples were studied by Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), energy dispersive X-ray spectroscopy (EDS), and transmission electron microscopy (TEM). FT-IR results depicted that the flavonoids, phenolics, and tannins from <em>M. communis</em> extract can play significant roles in reducing and immobilizing Au NPs. Their antibacterial properties were evaluated thoroughly against pathogenic bacterial strains of Gram-positive (<em>Staphylococcus aureus, Enterococcus faecalis</em>) and Gram-negative (<em>Escherichia coli</em> and <em>Pseudomonas aeruginosa</em>) utilizing the agar disc diffusion approach. In addition, MIC (Minimum Inhibitory Concentration) and MBC (Minimum Bactericidal Concentration) were obtained by employing the macro dilution method. Thus, the fabricated Fe₃O₄@<em>M. communis</em>/Au nanocomposite could serve as an effective antimicrobial agent to overcome multi-drug-resistant bacteria.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"15 ","pages":"Article 102323"},"PeriodicalIF":2.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143917512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Plasma Lipidomics of HIV-1 infected patients based on ultra performance liquid chromatography–mass spectrometry","authors":"Aoxin Ma ,&nbsp;Zhaobo Wu ,&nbsp;Guojun Li ,&nbsp;Xinyu Zhang ,&nbsp;Xiangyun Tang ,&nbsp;Shuofan Dong ,&nbsp;Xinli Lu ,&nbsp;Kaoqi Lian","doi":"10.1016/j.rechem.2025.102289","DOIUrl":"10.1016/j.rechem.2025.102289","url":null,"abstract":"<div><div>Acquired immune deficiency syndrome (AIDS) has been shown to not only attack the body's immune system but also to cause metabolic disorders. Highly active anti-retroviral therapy (HAART) is the main treatment for AIDS, but it can also affect the human metabolic system and cause metabolic disorders. In this study, we analyzed how AIDS and HAART alter human metabolism through an ultra performance liquid chromatography–mass spectrometry (UPLC-MS) lipidomics approach. Differential metabolites with significant changes were identified by multivariate statistical analysis. There were 44 significantly different metabolites detected in the healthy volunteers and HAART-naïve patients, and 61 significantly different metabolites detected in the healthy volunteers and patients under HAART. Screening for biomarkers based on the area under the receiver operating characteristic curve. In the healthy and untreated groups, Sphinganine was identified as potential biomarkers. In the healthy and treated groups, Psychosine and Sphinganine were identified as potential biomarkers. Sphinganine and Psychosine as biomarkers have a wide range of potential clinical applications. In psychiatric disorders and metabolic disorders they can provide new directions for early diagnosis, therapeutic monitoring, and prognostic assessment of diseases. Future studies will further explore the specific mechanisms and clinical application value of these biomarkers.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"15 ","pages":"Article 102289"},"PeriodicalIF":2.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143891137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improved corrosion inhibition effect of a green three-component compound to Q235 steel in acidic solution","authors":"Chengjia Bao ,&nbsp;Weijian Qi ,&nbsp;Zhuanjun Zhu ,&nbsp;Ting Xu ,&nbsp;Long Zhao ,&nbsp;Yanhong Ma ,&nbsp;Yang Liu ,&nbsp;Bowen Yang ,&nbsp;Xueru Luo ,&nbsp;Hui Yun ,&nbsp;Xiaojuan Li","doi":"10.1016/j.rechem.2025.102316","DOIUrl":"10.1016/j.rechem.2025.102316","url":null,"abstract":"<div><div>Chitosan (Chi), curcumin (Cur) and geraniol (Ger) are natural compounds, which can potentially serve as green corrosion inhibitors. Herein, the corrosion inhibition efficiency (IE) of them was compared. The corrosion rate of 1.5 mM Chi on the 1 st d was 0.78 ± 0.41 g/ (m² h), significantly lower than that of the control group (CK) (2.59 ± 0.32 g/ (m² h)), while the corrosion rate of 2 mM Cur decreased by 8.48–18.71 times. The corrosion IE of 1.5 mM Ger remained above 60 % for over 15 days. To improve corrosion IE on Q235 steel in acidic solution, two-component and three-component compounds of them at their optimal IE concentrations were also tested and evaluated by weight loss and electrochemical analysis. Chi+Cur + Ger exhibited the minimum growth rate of corrosion rate (0.19–15.36 g/ (m² h)) and the maximum corrosion IE (81.87–96.41 %) during 20 days. The weight loss was 20.65 % of the control on the 20th day. The Tafel results indicated Chi+Cur + Ger functioned as a mixed-type corrosion inhibitor, inhibiting the cathodic reaction more significantly. The surface observation and X-ray photoelectron spectroscopy (XPS) proved the formation of an adsorption layer on the steel surface. Chi and Cur could adsorb on the steel surface through chemical interaction like by amine and/or hydroxyl groups, while Ger through physical adsorption. The synergistic anticorrosion layer not only prevented steel surface from corrosive solution attack, but also increased the resistance to retard the charge transfer in the solution. The results might shed new insight in the application of green complex for steel corrosion inhibition.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"15 ","pages":"Article 102316"},"PeriodicalIF":2.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143903625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Crystal enigma: Understanding diverse protein conformational dynamics, ligand selectivity and interaction in multi-space group crystals using computational modelling","authors":"Mbalenhle Mfeka ,&nbsp;Olalekan Onisuru ,&nbsp;Ramesh Pandian ,&nbsp;Yasien Sayed ,&nbsp;Thandeka Khoza ,&nbsp;Ikechukwu Achilonu","doi":"10.1016/j.rechem.2025.102288","DOIUrl":"10.1016/j.rechem.2025.102288","url":null,"abstract":"<div><div>Empirical structural methods have been instrumental in drug design, but they often fall short of capturing protein dynamics. To address this limitation, computer-aided drug design (CADD) is essential. Given that <em>Schistosoma bovis</em> 28 kDa-Glutathione <em>S</em>-Transferase (<em>Sb</em>28GST) is a promising anti-schistosome drug target, a careful selection of crystal structure space groups used for CADD is emphasized in this study. <em>Sb</em>28GST was successfully overexpressed and purified to grow protein crystals with a resolution of 2.4 Å in an orthorhombic space group system. High-throughput virtual screening (HTVS) of a flavonoid compound was performed on monoclinic 8ALS and orthorhombic 8BHZ Sb28GST to identify potential ligands. The results showed a diverse selection of hit compounds with apigenin 7-O-(2G-rhamnosyl)gentiobioside (apigenin) being the common ligand. However, quercetin-3-O-Beta-<span>d</span>-Glucose-7-O-Beta-D-Gentiobioside (quercetin) showed the highest affinity to 8ALS with a Glide gscore of −15.66 kcal/mol. Also, 500-ns molecular dynamics simulations (MDS) of the 8ALS-<em>Sb</em>28GST and 8BHZ-<em>Sb</em>28GST apo systems, as well as their corresponding apigenin and quercetin complexes, show two distinct trajectories which reveal significant differences in their dynamic behaviour and also showed varying interactions. This highlights the need for collective assessment of protein polymorphs to comprehensively understand protein dynamics. The inhibitory potency of apigenin and quercetin via a GSH-CDNB conjugation assay confirmed that they significantly reduced the specific enzyme activity of <em>Sb</em>28GST with both ligands having half-maximal inhibitory concentration (IC₅₀) of 0.13 mM. Extrinsic fluorescence studies and thermal shift assay indicated that these compounds bind to the hydrophobic H-site and allosteric L-site at the dimer interface and have a minimal effect on the protein's thermal stability.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"16 ","pages":"Article 102288"},"PeriodicalIF":2.5,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143935356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"N-(1-hydroxybutan-2-yl)-4-nitrobenzene sulfonamide: A novel organocatalyst for an effective one-pot synthesis of α-amino phosphonates","authors":"Swati Jaydeokar ,&nbsp;Vikas G. Yadav ,&nbsp;Priyanka V. Bandivadekar ,&nbsp;Ganesh Chaturbhuj ,&nbsp;Vijaykumar L. Chavan","doi":"10.1016/j.rechem.2025.102295","DOIUrl":"10.1016/j.rechem.2025.102295","url":null,"abstract":"<div><div>This study emphasizes an efficient method for a one-pot, three-component reaction of aromatic aldehyde/ketone, amines, and dialkyl phosphite to produce α-Amino phosphonates. This reaction was catalyzed by a novel organocatalyst <em>N</em>-(1-hydroxybutan-2-yl)-4-nitrobenzene sulfonamide. The acidity of the synthesized catalyst was increased due to SO₂-NH group which was used in Kabachnik Field reaction. The main advantages of the current method include inexpensive, non-toxic, efficient organo catalyst, high yields, a reduced reaction time, green solvent, an easy experimental method, a simple workup procedure, and the suitability of the catalyst to withstand a wide range of substrate scope All aromatic, heterocyclic aldehydes and cyclic ketone variations reacted effectively producing greater yields of the respective α-amino phosphonates in a shorter reaction time (26) examples. Additionally, the catalyst was easily recovered and reused over several cycles without significantly decreasing effectiveness. This provides economic and environmental benefits.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"16 ","pages":"Article 102295"},"PeriodicalIF":2.5,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143922002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancements in multifunctional nanomaterials for synergistic photocatalytic and adsorptive water treatment processes","authors":"Athba Sabhan Khalaf ,&nbsp;Zainab Y. Shnain ,&nbsp;Alaa Dhari Jawad Al-Bayati ,&nbsp;Hasan Sh. Majdi ,&nbsp;Mohammad F. Abid ,&nbsp;Ahmed Abdalhussein Bilal ,&nbsp;Adnan.A. Alsalim ,&nbsp;Nour Hamid Abdrahman ,&nbsp;Aswar A. Alwasiti","doi":"10.1016/j.rechem.2025.102292","DOIUrl":"10.1016/j.rechem.2025.102292","url":null,"abstract":"<div><div>Wastewater generated from different anthropogenic activities often poses health risks to both human and aquatic lives which necessitate the development of advanced remediation technologies using multifunctional nanocomposites. There is an increasing interest in the application of multifunctional nanocomposites for wastewater treatment due to their tendency to be used in combined photocatalytic and adsorption process. The multifunctional nanocomposites offer synergistic effects which provide opportunities for efficient capture of the contaminants and subsequently degrading them under various environmental conditions. The recent advances in the applications of multifunctional nanocomposites include the design of photocatalysts that could be applied under visible light irradiation, surface modified adsorbents, and heterojunction nanomaterials. Multifunctional nanocomposites have displayed noteworthy performance in the removal of organic contaminants such as dyes, pharmaceuticals residues, phenols as well as heavy metals with enhanced stability, reusability and scalability. Key advancements in the application of the multifunctional nanocomposite, and the various mechanism in the adsorption and photocatalytic process have been highlighted in this review. The review presented a future perspective with an emphasis on the necessity of cost-effectiveness and environmentally sustainable nanomaterials to ensure sustainable wastewater treatment technologies.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"15 ","pages":"Article 102292"},"PeriodicalIF":2.5,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143882671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}