Results in Chemistry最新文献

{"title":"Magnetic MOF–ionic liquid composite hydrogel for rapid MSPE-HPLC-FLD determination of aflatoxins in corn","authors":"Danna Liᵃ,&nbsp;Liqin Yuᵇ","doi":"10.1016/j.rechem.2026.103633","DOIUrl":"10.1016/j.rechem.2026.103633","url":null,"abstract":"<div><div>A magnetic composite hydrogel was developed as a novel adsrobent for magnetic solid-phase extraction of aflatoxins in corn prior to high-performance liquid chromatography-fluorescence detection. The material integrates Fe₃O₄ magnetic nanoparticles, NH₂-UiO-66, imidazolium-based ionic liquid, and chitosan hydrogel, forming a multifunctional adsorbent with enhanced adsorption performance. Benefiting from the synergistic effects of π–π interactions, hydrogen bonding, electrostatic attraction, and hydrophobic interactions, the composite hydrogel exhibited excellent affinity toward aflatoxins. Under optimized conditions, rapid adsorption equilibrium was achieved within 3 min. The proposed method showed good linearity (R² &gt; 0.9985), with limits of detection of 0.1–0.5 μg/kg. Spiked recovery experiments in corn samples yielded satisfactory recoveries ranging from 74% to 113% with relative standard deviations between 3.8% and 19.7 (<em>n</em> = 3). The developed method provides a simple, rapid, and reliable approach for trace determination of aflatoxins in complex cereal matrices.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"28 ","pages":"Article 103633"},"PeriodicalIF":5.8,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148641802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A compact flow-based system for the determination of copper(II) and zinc(II) in water using solid-phase extraction coupled with pH modulation","authors":"Francisca T.S.M. Ferreira,&nbsp;Tânia C.F. Ribas,&nbsp;Ana Machado,&nbsp;Adriano Bordalo,&nbsp;Raquel B.R. Mesquita,&nbsp;António O.S.S. Rangel","doi":"10.1016/j.rechem.2026.103631","DOIUrl":"10.1016/j.rechem.2026.103631","url":null,"abstract":"<div><div>Metals such as copper(II) and zinc(II) can be found in natural and drinking water sources. However, at high concentrations, they pose significant risks to human health. In this context, the main goal of this work was to develop a sequential injection system for the determination of copper(II) and zinc(II) in freshwater. The selectivity of the quantification was controlled by adjusting the colorimetric reaction pH and by implementing an in-line solid-phase extraction strategy. Copper(II) was determined at pH 5, whereas zinc(II) was determined at pH 9 after retention of copper(II) on the resin column. The developed method enabled the quantification of copper(II) and zinc(II) in the concentration ranges of 11.3–500 μg/L and 19.9–500 μg/L, with detection limits of 4.10 and 6.61 μg/L, respectively. The relative standard deviation for the copper(II) and zinc(II) quantification was 2.0% and 4.7%, respectively. The method was validated through the analysis of natural water samples, since the results obtained with the developed method were not significantly different from those obtained with the reference procedure (ICP-OES). Additionally, recovery studies were performed, yielding 97 ± 3% and 98 ± 7% for copper(II) and zinc(II), respectively. The greenness of the developed method and the reference procedure was assessed using the AGREE tool. The reference method achieved a score of 0.59, whereas the developed method obtained a higher score of 0.71. The improvement in the score was associated with the more miniaturised, energy-efficient, and potentially on-site analysis nature, which makes it a promising tool for routine environmental monitoring.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"28 ","pages":"Article 103631"},"PeriodicalIF":5.8,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148641059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent advancements in magnetic nanoparticles-based lab-on-a-chip detection systems","authors":"Zahra Golsanamlu,&nbsp;Abolghasem Jouyban,&nbsp;Jafar Soleymani","doi":"10.1016/j.rechem.2026.103655","DOIUrl":"10.1016/j.rechem.2026.103655","url":null,"abstract":"<div><div>Lab-on-a-chip (LOC) devices have emerged as promising technology for rapid, miniaturized, cost-effective biomedical analytic systems, particularly for point-of-care (POC) diagnostics. Of the various nanomaterials used in LOC systems, magnetic nanoparticles (MNPs) have attracted a lot of attention because of their unique magnetic behavior, biocompatibility, high surface-area-to-volume ratio, and capacity to facilitate effective target separation and signal enhancement. The integration of MNPs with microfluidic and smartphone-assisted LOC platforms has considerably enhanced the sensitivity, mobility, and analytical performance of current biosensing systems. This study outlines current improvements reported during the past 5–7 years in MNP-based LOC technologies for biomedical applications. Along with commonly used sensing techniques, the roles of MNPs in sample processing, target preconcentration, biological separation, and signal amplification were discussed. Furthermore, the effectiveness of these systems, their benefits and drawbacks, challenging opportunities, and future directions for the design of high-performance, portable MNP-enabled LOC biosensors are critically assessed.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"28 ","pages":"Article 103655"},"PeriodicalIF":5.8,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148641798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electrochemical detection of enzalutamide based on the coupling of the reduced graphene oxide and molecularly imprinted polymer","authors":"Shokofeh Mahmodnezhad,&nbsp;Mahmoud Roushani,&nbsp;Zahra Mirzaei Karazan","doi":"10.1016/j.rechem.2026.103657","DOIUrl":"10.1016/j.rechem.2026.103657","url":null,"abstract":"<div><div>Herein, a cost-effective molecularly imprinted electrochemical sensor was developed for detecting the anti-androgen medication Enzalutamide (ENZA) using reduced graphene oxide (rGO) and para-phenylenediamine (p-PD). The molecularly imprinted polymer (MIP) was synthesized on a glassy carbon electrode (GCE) modified with rGO by electropolymerizing the p-PD monomer in the presence of the ENZA analyte. SEM and FT-IR were used to characterize the synthesized materials and the imprinted polymer. Additionally, the MIP's electrochemical behavior and analytical performance were assessed using differential pulse voltammetry (DPV) and cyclic voltammetry (CV). The proposed sensor showed a linear response over 5–130 nM, with a detection limit (LOD) of 1.66 nM. Its practical applicability was verified by analyzing pharmaceutical tablet samples, yielding relative recoveries of 99.89–100.64% and relative standard deviations (RSDs) not exceeding 2.1%, highlighting the suitability of the ENZA electrochemical sensor for clinically relevant measurements.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"28 ","pages":"Article 103657"},"PeriodicalIF":5.8,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148641067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eco-friendly biosynthesis of silver nanoparticles using marine algal extract and their biomedical applications","authors":"J. Jancy Helan,&nbsp;A. Thirumurugan,&nbsp;S. Alagumanian,&nbsp;K. Vignesh","doi":"10.1016/j.rechem.2026.103606","DOIUrl":"10.1016/j.rechem.2026.103606","url":null,"abstract":"<div><div>Marine algal extract mediated production of silver nanoparticles (AgNPs) has attracted substantial attention due to their eco-friendly synthesis and biomedicinal potential. The aim of the present work was to synthesize AgNPs using hydroalcoholic extract of <em>Porphyra laciniata</em> and assess their physicochemical features, antioxidant, antibacterial and anticancer activity. The formation of AgNPs was confirmed by UV-Visible spectroscopy with a surface plasmon resonance peak at 430 nm. FTIR, XRD, SEM, EDS, particle size and zeta potential analysis affirmed the effective synthesis, crystallinity, shape, elemental content and stability of the nanoparticles. The synthesized AgNPs showed dose-dependent antioxidant activity with IC₅₀ values of 62.166 μg/mL and 45.556 μg/mL (DPPH and ABTS, respectively). The antibacterial activity increased with concentration, maximum zone of inhibition was found against <em>Staphylococcus aureus</em> (4.96 ± 0.54 mm at 75 μL) followed by <em>Klebsiella pneumoniae</em> (3.63 ± 0.39 mm), <em>Escherichia coli</em> (3.26 ± 0.41 mm) and <em>Vibrio cholerae</em> (3.20 ± 0.63 mm). Moreover, AgNPs showed strong dose dependent cytotoxicity against cancer cells with an IC₅₀ value of 63 μg/mL. Cytotoxicity was further validated by AO/EtBr and Hoechst 33258 staining showing apoptotic cell death. These results indicate that <em>P. laciniata</em>-mediated AgNPs contain potential antioxidant, antibacterial and anticancer activities and can serve as a possible option for future biological applications.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"28 ","pages":"Article 103606"},"PeriodicalIF":5.8,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148641793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"‘Isolation, structural characterization, and antidiabetic evaluation of the novel bioactive oligosaccharide, Mangomeligoside’","authors":"Akanksha Yadav,&nbsp;Aparna Sharma,&nbsp;Ashutosh Ranjan,&nbsp;Bhawna,&nbsp;Syed Mohd Atif,&nbsp;Shashi Bala","doi":"10.1016/j.rechem.2026.103629","DOIUrl":"10.1016/j.rechem.2026.103629","url":null,"abstract":"<div><div>Honey, sweeten in taste, a rich source of various mannose, glucose, galactose and fructose sugar, previously reported for wound healing, anti-oxidant, antimicrobial, anticancer, and also reported for antidiabetic properties. To avoid sugar intake, most of the diabetic persons replace sugar by honey. High glycemic index (GI), indicates, high blood sugar level in human body, and medically termed as Diabetes Mellitus, which is one of the metabolic diseases. It indicates chronic hyperglycemia that triggers the carbohydrate, fat and protein metabolism disorders in the human body and may lead to long-term damage of various organs. In present research work, isolation of novel oligosaccharide-Mangomeligoside, has been done by silica column chromatography and structure elucidation is done with the help of 1D NMR<img>1H, 13C and 2D NMR HSQC, TOCSY, COSY and HMBC spectroscopic experiments. The molecular mass of the compound was confirmed by ES-MS experiment and their molecular formula is C42H72O36 which is confirmed by presence of peaks of their molecular ion peak and daughter ions (MS/MS) in Mass spectrum. In previous research work, honey reported as novel antidiabetic agent due to lower increase in serum insulin and C-peptile level with comparison to dextrose, glucose-fructose solution and may increases insulin concentration. Keeping this finding in mind, the isolated novel hepta-saccharide, Mangomeligoside, and crude honey sample, were screened for glucose lowering effect on STZ-induced diabetes mice. The results indicated that Mangomeligoside reduces the blood glucose in diabetic mice. For diabetic patients, honey sample taken as a natural sweetener, and the isolated novel compound ‘Mangomeligomide’ showed glucose lowering effect, which could be a new milestone finding in the field of carbohydrate research.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"28 ","pages":"Article 103629"},"PeriodicalIF":5.8,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148640987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Paraffin based form-stable phase change composite with chitosan@polypyrrole aerogel as skeleton carrier for low temperature thermal energy storage and efficient photothermal conversion","authors":"Shengxian Hou,&nbsp;Jin Wang,&nbsp;Jiawen Xu,&nbsp;Yanjiang Zhao,&nbsp;Chengjie You,&nbsp;Chuan Li,&nbsp;Geng Qiao","doi":"10.1016/j.rechem.2026.103641","DOIUrl":"10.1016/j.rechem.2026.103641","url":null,"abstract":"<div><div>This work focuses on the development of a paraffin-based shape stabilization phase change composite containing chitosan@polypyrrole aerogel as a skeleton carrier for low temperature thermal energy storage and efficient photothermal conversion. Such a composite is fabricated by incorporating the three-dimensional network aerogel, that synthesized through the deposition of polypyrrole on the pores of chitosan using the in situ oxidation and polymerization processes. Characterization results indicate that polypyrrole and chitosan are bonded via hydrogen bridges, forming a rigid and open-celled network structure that is able to accommodate the liquid paraffin with a mass ratio as high as 93.25%. At such a composition, the composite achieves a melting temperature of 36.86 °C and a latent heat of 194.95 J/g. The doping of polypyrrole largely improves the composite thermal stability and thermal conductivity. In comparison with the pure paraffin, the thermal decomposition temperature and thermal conductivity of the composite containing 9.66 wt% chitosan@polypyrrole aerogel are respectively enhanced by 33.7% and 3.26 times. Splendid thermal cycling performance is also achieved in the composite. After 300 repeated heat-cold cycles, the paraffin concentration is only decreased by 4.35%, and no apparent leakage or deformation is observed in the composite. Photothermal conversion tests reveal that polypyrrole endows the composite with highly efficient broadband light absorption capabilities. Under simulated sunlight irradiation of 100 mW/cm², the heating rate of the composite can reach 33.74 °C/h, and the photothermal conversion efficiency is up to 73.22%.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"28 ","pages":"Article 103641"},"PeriodicalIF":5.8,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148641064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biosynthesis of Mn3O4 nanoparticles using leaf extract of Cicer Arietinum for oxidase mimicking and antibacterial activities","authors":"Nidhal Meena Sher Mohammad","doi":"10.1016/j.rechem.2026.103530","DOIUrl":"10.1016/j.rechem.2026.103530","url":null,"abstract":"<div><div>Biosynthesized metal oxide nanoparticles (MONPs) have triggered a substantial research interest due to their advancements and diverse applications. In this study, aqueous phase green synthesis of Mn₃O₄ nanoparticles (NPs) using <em>Cicer Arietinum l</em>eaf extract was elucidated for the first time. The phytochemicals of the extract can act as potential reducing and capping agents in the nanoparticle's fabrication process. The tailored Mn₃O₄ NPs were characterized using various techniques, including UV–Vis, FE-SEM, EDS, FTIR, and XRD. The results revealed the formation of pure Mn₃O₄NPs with an average crystallite diameter of 13.51 ± 0.24 nm. Biologically synthesized Mn₃O₄ NPs exhibited oxidase-like activity and can catalyze the oxidation of 3, 3′, 5, 5′ -tetramethylbenzidine (TMB) to produce a blue oxidized TMB (ox-TMB). The kinetic K_m and V_max parameters were determined for the synthesized Mn₃O₄ nanozymes to be 0.0333 mM and 1.11 × 10⁻⁸ M s⁻¹, respectively. Accordingly, an efficient colorimetric detection of ascorbic acid (AA) was attained based on fading the blue color of ox-TMB. The colorimetric system showed good linearity (R² = 0.9935) at concentration levels ranging from 10 to 70 μM, with LOD of 6.3 μM, and high selectivity for detecting AA in orange juice samples with reasonable accuracy and precision. The antibacterial activity of biosynthesized Mn₃O₄ NPs was also tested against bacterial growth of both types of gram positive and gram negative using well diffusion method. The prepared Mn₃O₄ NPs possess remarkable antibacterial effect particularly on gram positive bacteria of <em>Enterococcus faecalis</em>. This study highlighted the use of <em>Cicer Arietinum</em> leaf waste for the synthesis of Mn₃O₄ NPs as nanozymes and potential antibacterial agents, suggesting their applications in biochemical sensing, pharmaceutical, and food packaging.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"28 ","pages":"Article 103530"},"PeriodicalIF":4.2,"publicationDate":"2026-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148183158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Authenticity verification and fraud detection in turmeric powder based on aroma and taste profiles using electronic nose, electronic tongue and artificial intelligence","authors":"Ahmad Jahanbakhshi ,&nbsp;Yousef Abbaspour-Gilandeh ,&nbsp;Kobra Heidarbeigi ,&nbsp;Mahmoud Roushani ,&nbsp;Mohammad Momeny","doi":"10.1016/j.rechem.2026.103520","DOIUrl":"10.1016/j.rechem.2026.103520","url":null,"abstract":"<div><div>Spices are usually the most widely used ingredients in the food industry, which are sold in bulk and powdered form in the market, and the possibility of adulterating them is very high. Therefore, the main reason for conducting this piece of research is the demand for new and accurate methods that measure the authenticity and quality of spices (such as turmeric powder) through electronic nose and electronic tongue systems. Unmarketability of 3rd grade chickpeas and their very low price has become an excuse for some profiteers to mix them with turmeric powder and sell them in the market. In this research, samples of turmeric powder were prepared in 13 classes and electronic nose and electronic tongue systems were used to evaluate their quality and detect fraud. Finally, the results obtained from the output of these systems were evaluated and classified using machine learning algorithms (such as basic CNN, improved CNN, PCA, MLP, Fuzzy, SVM, KNN, GBT and EDT). The results showed that the electronic nose and electronic tongue systems in combination with the improved CNN are able to classify the samples of turmeric powder and fraud with 94.87% and 95.38% accuracy, respectively. The PCA method in the electronic nose system for evaluating the samples of turmeric powder and fraud obtained 96% and in the electronic tongue system 97% of the variance between the studied samples.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"28 ","pages":"Article 103520"},"PeriodicalIF":4.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148183159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"pH-responsive quercetin delivery via chitosan/halloysite nanocomposite hydrogels: Enhanced anti-inflammatory and antibacterial properties","authors":"Ali Asghar Khalifeh ,&nbsp;Mehrab Pourmadadi ,&nbsp;Zohreh Arefi Khorrami ,&nbsp;Majid Abdouss ,&nbsp;Saeed Saber Samandari","doi":"10.1016/j.rechem.2026.103491","DOIUrl":"10.1016/j.rechem.2026.103491","url":null,"abstract":"<div><div>The present study reports a novel chitosan/halloysite nanotube (CS/HNT) nanocomposite hydrogel system for the controlled delivery of quercetin, to overcome its poor solubility and bioavailability limitations. The nanocomposite achieved 42% drug loading capacity and 83.5% encapsulation efficiency. In vitro studies showed pH-responsive behavior over 96 h with maximum drug release (92%) at pH 5.4, indicating increased availability in inflammatory conditions. The release mechanism followed Fickian diffusion that was corroborated by kinetic modeling. The successful synthesis and compatibility were confirmed via FTIR, XRD, and FESEM characterization techniques while analysis with DLS showcased a particle homogeneous distribution of 218.6 nm size alongside sufficient colloidal stability with the measure of a zeta potential standing at +48.2629 mV. These nanocomposites exhibited excellent biocompatibility on L929 fibroblast cells with very interesting antimicrobial results against both <em>Staphylococcus aureus</em> and <em>Escherichia coli</em>. These findings establish CS/HNT nanocomposite hydrogels as promising carriers for anti-inflammatory drug delivery, offering enhanced therapeutic efficacy with controlled release properties.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"28 ","pages":"Article 103491"},"PeriodicalIF":4.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148183160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}