{"title":"Paraganglioma of the ponytail in one case","authors":"A. Belhachmi, M. Gazzaz, B. Elmostarchid","doi":"10.15406/OAJTMR.2017.01.00016","DOIUrl":"https://doi.org/10.15406/OAJTMR.2017.01.00016","url":null,"abstract":"A 19-year-old patient with no significant medical or surgical pathological antecedents who presented 5-month-old chronic, intermittent low back pain that became more and more intense, aggravated by lumbar lungosciatalgia L5, with heaviness of the lower left limb and walking, without sphincteric disorders, nor saddle anesthesia, nor trophic disorders. Clinical examination showed a distal paresis of the foot ghe, the patient does not hold the maingazini, hypotone member. The osteo-tendinous reflexes were abolished, babinski positive, on the other hand the somatic examination was without particularities. The standard radiography of the lumbar spine was normal [1-3].","PeriodicalId":410359,"journal":{"name":"Journal of Translational Medicine and Research","volume":"203 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114660038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Spiral artery remodeling in pregnancy","authors":"Nidhi Sharma","doi":"10.15406/OAJTMR.2017.01.00015","DOIUrl":"https://doi.org/10.15406/OAJTMR.2017.01.00015","url":null,"abstract":"Brosen et al. suggested that the “physiological change” of spiral arteries in the pregnant uteri was a result of the destructive action of invading trophoblast on vascular smooth muscles and elastic membranes [5]. Later, a maternal contribution had to be considered since some changes in the maternal vessel wall precede the antidromic migration of trophoblast along the vessel lumen. Some researchers believe that the local intravasation of interstitial trophoblast is more likely [6].","PeriodicalId":410359,"journal":{"name":"Journal of Translational Medicine and Research","volume":"4 8","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132365521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Khushmatov, P. Usmanov, U. K. Inogamov, Z. Toshmatov, H. Aisa, K. Eshbakova
{"title":"Possible involvement of no–synthase in inotropic effect of 4’,5–dihydroxy–7–methoxyflavon in rat cardiac muscle","authors":"S. Khushmatov, P. Usmanov, U. K. Inogamov, Z. Toshmatov, H. Aisa, K. Eshbakova","doi":"10.15406/oajtmr.2017.01.00014","DOIUrl":"https://doi.org/10.15406/oajtmr.2017.01.00014","url":null,"abstract":"Treatment of cardiovascular diseases includes a wide range of pharmacological drugs, and plant remedies are suitable alternatives to synthetic drugs due to their availability, non–proarrhythmic characteristics, and minimal side effects.1 Medicinal plants distributed in the Central Asia and China provides abundant and precious medicinal resources for the Traditional Medicine in treating diseases.2 Flavonoids are unique secondary metabolites are synthesized in almost all plant cells, exhibiting high biological activity and due to their properties increasingly finding wide practical application in pharmacology and medicine. A wide range of biological activities and low toxicity puts them in a row promising compounds in this respect. Therefore, in pharmaceutical industry researches find cure against many various diseases, the direction of tendency is observed towards the growth of interest to search and create medical products based on bioflavonoids.3–8 Also, nowadays, in chemical researches have extracted and identified many bioflavonoid from plants.7,9–12 However, their mechanisms of cardio pharmacological impact have not been studied yet. Therefore, the aim of the present study was to involvement of NO–synthase in inotropic effect of 4’,5–dihydroxy–7– methoxyflavon in rat papillary muscle.","PeriodicalId":410359,"journal":{"name":"Journal of Translational Medicine and Research","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117037700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. D. Elsiddig, Ibrahim O. Jabra, A. Dabora, S. Z. Ibrahim
{"title":"An unusual presentation of advanced pancreatic cancer: coeliac axis occlusion and acute upper gut ischemia","authors":"H. D. Elsiddig, Ibrahim O. Jabra, A. Dabora, S. Z. Ibrahim","doi":"10.15406/oajtmr.2017.01.00024","DOIUrl":"https://doi.org/10.15406/oajtmr.2017.01.00024","url":null,"abstract":"Celiac artery thrombosis with ischemia is a rare condition associated with risk factors for thrombosis or embolism. The manifestation is rare because of the large number of collaterals between the coeliac and superior mesenteric artery. Advanced pancreatic cancer may cause gradual occlusion with collaterals which needs special attention during pancreaticoduodenectomy. No case was reported with acute thrombosis and acute upper gut ischemia.","PeriodicalId":410359,"journal":{"name":"Journal of Translational Medicine and Research","volume":"88 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125531799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laila Khalid AlKhaldi, Nadia Ahmad AlSaffar, Maryam Hajj Alipour, Hend Faraj, Sarah Bin Salama, Abdulwahab A. Borahmah, A. Albatineh
{"title":"Quality of life comparison between hemodialysis and peritoneal dialysis among end-stage renal disease patients in Kuwait","authors":"Laila Khalid AlKhaldi, Nadia Ahmad AlSaffar, Maryam Hajj Alipour, Hend Faraj, Sarah Bin Salama, Abdulwahab A. Borahmah, A. Albatineh","doi":"10.15406/OAJTMR.2017.01.00013","DOIUrl":"https://doi.org/10.15406/OAJTMR.2017.01.00013","url":null,"abstract":"Renal failure is a temporary or permanent damage to the kidneys, which results in loss of their normal function. There are two types of renal failure: acute renal failure and chronic renal failure. Chronic kidney disease (CKD) is used to cover all degrees of decreased renal function. The Kidney Disease Outcomes Quality Initiative (KDOQI) of the National Kidney Foundation (NKF) established a definition and classification of CKD. The KDOQI defines CKD as either kidney damage or a decreased glomerular filtration rate (GFR) of less than 60mL/min/1.73m2 for three or more months. The KDOQI classified CKD into 5 stages, with the last stage known as end-stage kidney disease (GFR<15mL/min/1.73m2).1,2","PeriodicalId":410359,"journal":{"name":"Journal of Translational Medicine and Research","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124533746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Emerging antibiotic resistance and plasmid dna in escherichia coli isolated from respiratory tract infections in Bangladesh","authors":"Shukla Promite, S. Saha, P. Roy","doi":"10.15406/oajtmr.2017.01.00011","DOIUrl":"https://doi.org/10.15406/oajtmr.2017.01.00011","url":null,"abstract":"Worldwide antibiotic resistance (AR) is a public health threat, places everyone at great risk.1 By 2050, it is anticipated that AR will cause 10 million deaths and US $60–100 trillion global economic loss if AR developing rate is constant as now.2 The rising bacterial resistance among Respiratory Tract Infections (RTI) has become a commonplace event. The resistance among RTIs causative pathogens of Streptococcus pneumoniae, Klebsiella pneumoniae, Pseudomonas aeruginosa and Escherichia coli contributes a significant cause of global morbidity and mortality as well.3–5 Additionally, inappropriate prescribing of antibiotics in RTIs has become a remarkable malpractice by prescribers.6,7 This practice further magnifies the emergence of antibiotic–resistant bacterial strains in addition to increased adverse effect, treatment cost, resource use and consultation with doctors.6,8 Difficulty in establishing bacterial etiology at the time of prescription in RTIs is another barrier to rational antibiotic prescribing in Bangladesh.9,10 The limited context specific surveillance data on antimicrobial sensitivity in Bangladesh further complicates antibiotic prescribing decisions by prescribers.10 The AR surveillance information has even paramount importance to develop local and national antibiotic guidelines.","PeriodicalId":410359,"journal":{"name":"Journal of Translational Medicine and Research","volume":"148 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128445601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amritveer Boparai, Junaid Niazi, Neha Bajwa, P. Singh
{"title":"Betulin a pentacyclic tri–terpenoid: an hour to rethink the compound","authors":"Amritveer Boparai, Junaid Niazi, Neha Bajwa, P. Singh","doi":"10.15406/OAJTMR.2017.01.00012","DOIUrl":"https://doi.org/10.15406/OAJTMR.2017.01.00012","url":null,"abstract":"Mother earth, a bionetwork enriched with plethora of remarkable plants holding numerous beneficial chemical compounds, which play an integral role in maintaining the lives stealth and safe. Betulin lup20 (29)–ene–3ß, 28–diol, a pentacyclictriterpene alcohol with a lupane skeleton is one of such chemical compounds contributing towards the advancement in field of medicine.1–3 It is obtained from outer bark of Birch trees.4–6 As described in Figure 1: Betulin has a pentacyclic ring structure and hydroxyl groups in positions C3 and C28. 7–9 Betulin in presence of acid agents undergoes rearrangement to form allobetulin.10 It is acknowledged that plants with lupine series are helpful in curing various diseases for this one relies on betulin which on conversion tobetulinic acid, the alcohol group replaced by a carboxylic acid group has more biological activity.2,7,10,11 The alcohol group cannot join with stationary phase because two groups are located on opposite sides of compound.1 Betulinic acid, the more bioactive compound exhibits choleritic, antihelmintic, powerful prophylactic, anti–HIV, antimutageneagent, antiviral, anti–fungal, anti–leukemia, anti–leishmanial, anti–inflammatory, immunomodulator.7,12–15","PeriodicalId":410359,"journal":{"name":"Journal of Translational Medicine and Research","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121465631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nephrolithiasis – an updated review in relation to diagnosis, prevention and treatment","authors":"D. Kapoor, Vyas Rb, D. Dadarwal","doi":"10.15406/OAJTMR.2017.01.00009","DOIUrl":"https://doi.org/10.15406/OAJTMR.2017.01.00009","url":null,"abstract":"Nephrolithiasis is one of the main ailment of the urinary tract and is a chief source of morbidity. Stone formation is one of the painful urologic disorders that happen in approximately 15% of the global population and its re–occurrence rate in males is 74–86% and 45–62% in female. Kidney stones are linked with chronic kidney disease. Preventing reappearance is precisely to the type of stone like calcium oxalate, calcium phosphate, cystine, magnesium ammonium phosphate and uric acid stones.1,2","PeriodicalId":410359,"journal":{"name":"Journal of Translational Medicine and Research","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115210198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Institutionalism in mental illnesses: a case report","authors":"P. K. Verma, S. Chaudhury, Prajakta Patkar","doi":"10.15406/oajtmr.2017.01.00010","DOIUrl":"https://doi.org/10.15406/oajtmr.2017.01.00010","url":null,"abstract":"","PeriodicalId":410359,"journal":{"name":"Journal of Translational Medicine and Research","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130434399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Malignant melanoma: case report and review of the literature","authors":"Mosqueira, E. Gómez, F. Bravo, Vega Jd, L. Soto","doi":"10.15406/OAJTMR.2017.01.00008","DOIUrl":"https://doi.org/10.15406/OAJTMR.2017.01.00008","url":null,"abstract":"Malignant melanoma (MM) or simply melanoma, is a malignancy of pigment production cells (melanocytes), localized primarily on skin.1 The incidence of MM has been increasing in the last, especially in light skin people population exposed to excessive solar radiation. The most important exogen factor is ultraviolet radiation, particularly intermittent exposition to sunlight.2 Despite being the least common skin cancer (approximately 4%), MM represents a high rate mortality.1 For this reason, early diagnosis is of vital importance to improve disease prognosis.","PeriodicalId":410359,"journal":{"name":"Journal of Translational Medicine and Research","volume":"95 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114691377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}