L. Solomin, K. L. Korchagin, E. Tyulkin, E. Shchepkina
{"title":"Ilizarov bone transport in large knee joint defect (case report)","authors":"L. Solomin, K. L. Korchagin, E. Tyulkin, E. Shchepkina","doi":"10.15406/OAJTMR.2018.02.00029","DOIUrl":"https://doi.org/10.15406/OAJTMR.2018.02.00029","url":null,"abstract":"Submit Manuscript | http://medcraveonline.com knee joint is a radical surgery for osteomyelitis, failed revision arthroplasty for oncology and Endoprosthesis replacement [35]. In case of impossibility of an operation for the next revision endoprosthetics of knee joint, the alternative to amputation and exoprosthetics is the operation of arthrodesis of the knee joint [2,6-8]. However, the presence of LKJD makes it impossible for acute shortening due to the invagination of soft tissue, vascular and neurological disorders. Therefore, for this kind of patients the reconstructive surgery based on of Ilizarov method is indicated [1,2,9]","PeriodicalId":410359,"journal":{"name":"Journal of Translational Medicine and Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121766347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Co-presentation of obstructive jaundice and primary hyperparathyroidism leading to diagnosis of cholangiocarcinoma","authors":"Saeeda Fatima, F. Ayesha","doi":"10.15406/OAJTMR.2018.02.00028","DOIUrl":"https://doi.org/10.15406/OAJTMR.2018.02.00028","url":null,"abstract":"Cholangiocarcinomas account for approximately three percent of all gastrointestinal malignancies. Although these cancers are rare in the United States, their frequency is increasing globally. These cancers are highly lethal because most are locally advanced at presentation and unresectable. Various studies have shown association between choledocholithiasis and cholangiocarcinoma.1,2 Other major risk factors identified include primary sclerosing cholangitis, inflammatory bowel disease, thorotrast, fibropolycystic liver disease, choledochal cysts, Caroli’s disease. Some genetic conditions such as Lynch syndrome and biliary papillomatosis also increase the risk for cholangiocarcinoma.3,4 Our case describes interesting finding of co–presentation of primary hyperparathyroidism (PHPT) along with cholangiocarcinoma. This makes the case intriguing as patient presented with symptoms of hypercalcemia, obstructive jaundice and pancreatitis initially thought to be secondary to PHPT. Later, diagnosis of cholangiocarcinoma makes PHPT just an incidental finding rather than cause of choledocholithiasis and subsequent cholangocarcinoma. Although PHPT can rarely present as pancreatitis due to biliary tract stones,5,6 no causal association has been described between PHPT and cholangiocarcinoma.","PeriodicalId":410359,"journal":{"name":"Journal of Translational Medicine and Research","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129420812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Chemical investigation of kankara kaolin for its pharmaceutical applications","authors":"Z. Christian, A. John, Z. Shehu","doi":"10.15406/oajtmr.2018.02.00027","DOIUrl":"https://doi.org/10.15406/oajtmr.2018.02.00027","url":null,"abstract":"Kaolin has the approximate chemical formula of H2Al2Si2O8(H2O) and is a white or yellow-white powder that has a slightly oily feel. It is an environmentally benign aluminosilicate mineral [9] that is insoluble in water [10]. Light kaolin is the preferred material for use in pharmaceutical preparations. The finely divided particles yield a very large surface area that adsorbs a wide variety of compounds [11].","PeriodicalId":410359,"journal":{"name":"Journal of Translational Medicine and Research","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126914950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. HarifetraMamyRichard, riamizao, A. Rakotondrainibe, M. Andriamanarivo
{"title":"Chest physiotherapy in newborns after surgical treatment of esophageal atresia: the alternative of ventilatory support in Madagascar","authors":"R. HarifetraMamyRichard, riamizao, A. Rakotondrainibe, M. Andriamanarivo","doi":"10.15406/OAJTMR.2017.01.00023","DOIUrl":"https://doi.org/10.15406/OAJTMR.2017.01.00023","url":null,"abstract":"Submit Manuscript | http://medcraveonline.com According to Patil RT et al. [4], elective postoperative ventilation in the management of EA with TEF allows the protection of the esophageal anastomosis following repair of esophageal atresia with trachea-esophageal fistula. Using ventilatory support in early post-operative period avoids the need for initial vigorous physiotherapy. Thus, the anastomosis can be rested and protected from injury; moreover, the prevention of postoperative respiratory distress could maintain adequate tissue PaO2.","PeriodicalId":410359,"journal":{"name":"Journal of Translational Medicine and Research","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123843627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Factors that motivated medical students at abia state university uturu to choose medicine as a career","authors":"Otuka Oai, N. Eleweke, O. Oworu","doi":"10.15406/OAJTMR.2017.01.00021","DOIUrl":"https://doi.org/10.15406/OAJTMR.2017.01.00021","url":null,"abstract":"Introduction Medicine is a noble profession which many people want to pursue for many reasons ranging from economic social and desire to help mankind. So many factors motivate people to choose medicine as a career. Motivation is an internal state that arouses, directs and maintains and sustains goal–oriented behaviour.1 In this questionnaire–based study we want to find what motivated a group of medical students to choose medicine as a career. Methodology This was a questionnaire based population study. Questionnaires were distributed to three levels of clinical students in Abia State University, Uturu. The data in the questionnaire included the following a) The love of science b) To save life c) Sickness in childhood d) Interest in medicine e) Grew up in the midst of medical personnel f) Social status g) Economic reasons h) Curiosity about human life i) It permits learning j) It is challenging k) Job security l) Close relative has an illness or died from an illness m) Pressure from family members n) Pressure from friends o) Pressure from community p) To be practical in life q) Because there is no physician in my family community r) Any other Respondents were encouraged to choose any number of the above options that influenced their decision to study medicine. The possible responses to each of the questions above were: i. Strongly agree. ii. Weakly agree. iii. Strongly disagree. iv. Weakly disagree. v. I do not know. The data was collated and analysed by manual calculations. Results The data collected was represented in the table below (Table 1)","PeriodicalId":410359,"journal":{"name":"Journal of Translational Medicine and Research","volume":"9 8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123799541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. E. Bakkaly, T. Lafia, Jaouad Bouljrouf, M. Rami, R. Belkacem, M. A. Bouhafs
{"title":"Urethral duplication in male children’s: report of four cases","authors":"A. E. Bakkaly, T. Lafia, Jaouad Bouljrouf, M. Rami, R. Belkacem, M. A. Bouhafs","doi":"10.15406/oajtmr.2017.01.00022","DOIUrl":"https://doi.org/10.15406/oajtmr.2017.01.00022","url":null,"abstract":"","PeriodicalId":410359,"journal":{"name":"Journal of Translational Medicine and Research","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130572745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Synthesis and structural properties characterization of ha/alumina and ha/mgo nanocomposite for biomedical applications","authors":"Vijayalakshmi.","doi":"10.15406/OAJTMR.2017.01.00020","DOIUrl":"https://doi.org/10.15406/OAJTMR.2017.01.00020","url":null,"abstract":"HAAlumina nanocomposite is biocompatible and has desirable mechanical and physical properties. Less cost, simple synthesis method, and fast production are the added advantages of this nanocomposite. Thus HA coatings on the surface of alumina substrates are used to combine excellent bioactivity of HA with superior mechanical properties of the alumina substrates. One of the elements associated with biological apatite is magnesium [1]. Mg incorporation into HAP stimulates osteoblast proliferation. Mg acts similar to a growth factor during the early stages of osteogenesis and promotes bone formation. Typical concentrations of carbonate and Mg ions in human bone are 5.8 and 0.55 wt %, respectively. Although the extent of these elemental substitutions is minimal, they are important for biological activity and interaction between bone mineral and calcium–phosphatebased implant materials by influencing crystal growth, dissolution rate, solubility, surface chemistry and charge, morphology, and the mechanical properties. By substitution of a smaller Mg ion or Al ion for a larger Ca ion, additional structural changes may be required to prevent destabilization/decomposition of the structure during heat treatment process. This can be achieved by co-substitution of a second ion, to the HA structure [2]. Thus, MgO and Alumina nanoparticles dispersed within polymer composites have the potential to enhance bone tissue formation with limited adverse degradation reactions. Taking advantage of these prior studies, the objective of the present in vitro study was to characterize MgO and Alumina nanoparticles as additive materials for orthopedic tissue engineering applications, especially when used in combination with HA nanoparticles [3]. Materials","PeriodicalId":410359,"journal":{"name":"Journal of Translational Medicine and Research","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114319495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Factors influencing clinician’s antibiotic prescribing behaviors (apb) in Bangladesh: an in–depth review using comb model","authors":"S. Saha, Shukla Promite","doi":"10.15406/OAJTMR.2017.01.00019","DOIUrl":"https://doi.org/10.15406/OAJTMR.2017.01.00019","url":null,"abstract":"Over the last decade, there are poly-pharmacy practices and extensive uses of antibiotics have become a commonplace in Bangladesh [1]. Overprescribing and unnecessary prescribing of antibiotics is a threatening problem in Bangladesh and worldwide [2]. The inappropriate use of antibiotics and development of antibiotic resistance (AR) are closely linked [3,4]. The annual death toll for AR is 700,000 globally [5]. Nowadays, AR is, therefore, a current global threat to public health. Therefore, promoting appropriate use of antibiotics is an emerging issue for patient safety and public health with national priority [6]. In 2014, Lundborg & Tamhanker [7,8] stated that human behavior is vigorously involved using antibiotics and developing antibiotic resistance. There are many decisions, which are taken prior to antibiotic prescription, dispensing, consumption or discarding influence subsequent human behavior. Individual involved might be a physician, health care provider, a veterinarian, an animal provider, a consumer, or a parent. The engagement of a human behavior is also observed in the non-human use of antibiotics in animal husbandry, industries, and agriculture.","PeriodicalId":410359,"journal":{"name":"Journal of Translational Medicine and Research","volume":"78 11","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114017100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diabetes is a disease characterized by impaired proteostasis","authors":"L. Bernstein","doi":"10.15406/oajtmr.2017.01.00018","DOIUrl":"https://doi.org/10.15406/oajtmr.2017.01.00018","url":null,"abstract":"The clinical feature of diabetes mellitus is unregulated hyperglycemia and impaired pancreatic insulin secretion. Diabetes is a systemic disease involving the pancreatic islet cell that produces insulin, and also the kidney, and eventual microvascular disease that has an impact on the heart and the brain. Opie [1] described hyalinization of the pancreatic islet cells prior to the discovery of insulin, and Kimmelstein and Wilson [2] observed hyalinization of the kidney glomeruli, also a hallmark of diabetic nephropathy, to which afferent arteriolar thickening (arteriolar nephrosclerosis) was later added. It can also be said that the hyalinization of the pancreatic beta cell and the kidneys is in either case amyloid deposit.","PeriodicalId":410359,"journal":{"name":"Journal of Translational Medicine and Research","volume":"255 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126781825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The history of off–pump coronary bypass (opcab)","authors":"F. Benetti, Natalia Scialacomo","doi":"10.15406/oajtmr.2017.01.00017","DOIUrl":"https://doi.org/10.15406/oajtmr.2017.01.00017","url":null,"abstract":"Submit Manuscript | http://medcraveonline.com technology and tools to operate on the unsupported beating heart. In 1952, Demikhov described the use of the LITA to directly graft the left anterior descending in dogs, with graft patency confirmed for up to 2-years [2]. Similar early success with the use of the ITA was reported by Canadian surgeon Gordon Murray [3]. Willian Longmire was apparently the first surgeon in performing an Offpump coronary artery bypass operation. He said they performed a couple of the earliest internal mammary coronary anastomosis when they were forced into it when the coronary artery they were endarterectomizing disintegrated and in the desperation they anastomoses the left internal mammary artery to the distal end of the right coronary artery [4].","PeriodicalId":410359,"journal":{"name":"Journal of Translational Medicine and Research","volume":"73 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117026714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}