Annals of the ICRP最新文献_第4页

Rethinking tissue reactions to radiation exposure: The tissue-sparing effect as a threshold for radiation-induced male infertility. 重新思考组织对辐射暴露的反应：组织保留效应作为辐射诱发男性不育的阈值。

Annals of the ICRP Pub Date : 2026-05-28 DOI: 10.1177/01466453251412161

H Fukunaga, K M Prise

{"title":"Rethinking tissue reactions to radiation exposure: The tissue-sparing effect as a threshold for radiation-induced male infertility.","authors":"H Fukunaga, K M Prise","doi":"10.1177/01466453251412161","DOIUrl":"https://doi.org/10.1177/01466453251412161","url":null,"abstract":"The principle of microbeam radiotherapy (MRT) is the delivery of a single high-dose fraction to a large treatment area divided into several smaller fields, to reduce the treatment's overall toxicity. Since the fundamental concept of MRT was first established, a notable tissue-sparing effect (TSE) has been confirmed in a large variety of species and tissue types, although the underlying biological mechanism in this process remains unclear. By coupling high-precision MRT with an ex-vivo mouse spermatogenesis model, we demonstrated the significant testicular TSE for maintaining spermatogenesis following MRT. To our knowledge, this was the first TSE identified in reproductive tissue. Our high-precision microbeam analysis also revealed that an efficient TSE for spermatogenesis relies on the size of the non-irradiated germ stem cell pool in the irradiated testicular tissues, suggesting the involvement of stem cell migration/competition. These findings of testicular TSE indicate that radiation infertility is not dose-dependent, but instead depends on micro-dosimetric conditions, and that the limit of the TSE is a potential threshold for radiation-induced male infertility.","PeriodicalId":39551,"journal":{"name":"Annals of the ICRP","volume":" ","pages":"1466453251412161"},"PeriodicalIF":0.0,"publicationDate":"2026-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148044068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The investigation of the impact of new ICRU95 operational quantities on the reference fields at JAEA-FRS in terms of the type-testing of the dosimeters. 在剂量计型式试验方面，调查新的ICRU95操作量对日本原子能机构- frs参考场的影响。

Annals of the ICRP Pub Date : 2026-05-28 DOI: 10.1177/01466453251411986

H Yoshitomi, T Tsuji, S Nishino, Y Tanimura

{"title":"The investigation of the impact of new ICRU95 operational quantities on the reference fields at JAEA-FRS in terms of the type-testing of the dosimeters.","authors":"H Yoshitomi, T Tsuji, S Nishino, Y Tanimura","doi":"10.1177/01466453251411986","DOIUrl":"https://doi.org/10.1177/01466453251411986","url":null,"abstract":"ICRU has published Report 95 jointly with ICRP in 2020 proposing new operational quantities. This will impact dosimetry in radiological protection especially for the dosimeters' performance of energy and angular dependence. To test the performance in detail, it is important to establish radiation reference fields corresponding to the new quantities. The Facility of Radiation Standards (FRS) of the Japan Atomic Energy Agency is a comprehensive Secondary Standard Dosimetry Laboratory in Japan equipped with various reference fields for x-, gamma-, beta-, and neutron radiations. We evaluated the conversion coefficients in terms of the new quantities in the FRS fields and demonstrated type-testing of commercial dosimeters based on the new quantities, which made it possible to conduct the performance tests of the dosimeters in terms of the new quantities at the FRS. Significant differences between the conversion coefficients for new and existing operational quantities were found for some FRS fields, especially for x-ray fields with low energies and large angles, beta-ray fields on the operational quantities for eye lens monitoring, and neutron radiation fields. The H* and Hp responses of the dosimeters were found to be affected at low-energy photon region accordingly.","PeriodicalId":39551,"journal":{"name":"Annals of the ICRP","volume":" ","pages":"1466453251411986"},"PeriodicalIF":0.0,"publicationDate":"2026-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148044059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Promoting digital tool usability for supporting everyday life in reconstruction areas after the Fukushima Daiichi nuclear power station accident: Results of a pilot study. 福岛第一核电站事故后，促进数字工具可用性以支持重建地区的日常生活：一项试点研究的结果。

Annals of the ICRP Pub Date : 2026-05-28 DOI: 10.1177/01466453251412101

T Ohba, A Goto, H Nakano, Y Koyama, K Honda, Y Fujita, Y Hirofuji, K Yoshida, K E Nollet, M Murakami, K Tanigawa

{"title":"Promoting digital tool usability for supporting everyday life in reconstruction areas after the Fukushima Daiichi nuclear power station accident: Results of a pilot study.","authors":"T Ohba, A Goto, H Nakano, Y Koyama, K Honda, Y Fujita, Y Hirofuji, K Yoshida, K E Nollet, M Murakami, K Tanigawa","doi":"10.1177/01466453251412101","DOIUrl":"https://doi.org/10.1177/01466453251412101","url":null,"abstract":"Comprehensive support for the everyday life of people in reconstruction areas around the Fukushima Daiichi nuclear power station should include access to specialists. This prompted the original development and recent user satisfaction survey of the 'Mimamoru Health Application' (MHApp), a digital tool connecting people to specialists and their expertise. To improve MHApp user satisfaction, user data from April 2021 to January 2023 were collected and analysed. Participants included affected populations (evacuees and returnees), unaffected residents, and local healthcare workers living in Fukushima Prefecture. Data included MHApp's system usability on a 0-100 scale [system usability scale (SUS)], user background characteristics, and free-text comments about using MHApp. In total, 47 participants joined this study. The number of days participants used MHApp was 17.3 ± 14.7 (mean ± SD). The SUS mean ± SD was 57.4 ± 13.2. Age-specific SUS scores were higher among users 20-40 years old than among users 50 + years old (p = 0.03). These results, along with free-text comments, suggest that improving the visualisation of various data and addressing the needs of users aged 50 years and older were key to better usability of MHApp.","PeriodicalId":39551,"journal":{"name":"Annals of the ICRP","volume":" ","pages":"1466453251412101"},"PeriodicalIF":0.0,"publicationDate":"2026-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148044105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Classification of harmful radiation-induced effects on human health for radiological protection purposes: history and concepts. 为放射防护目的对人体健康有害辐射影响的分类：历史和概念。

Annals of the ICRP Pub Date : 2026-05-27 DOI: 10.1177/01466453251412089

F Zölzer, L Vaillant, L Ainsbury, O Azimzadeh, C Badie, D Brown, A Francois, N Hamada, S Jacob, C Li, M Sasaki, C Zervides, D Laurier, T Schneider, H Carpenter, H Essop, V Hande, M Kocemba, J Lopes, A Valenti, A Woerner

{"title":"Classification of harmful radiation-induced effects on human health for radiological protection purposes: history and concepts.","authors":"F Zölzer, L Vaillant, L Ainsbury, O Azimzadeh, C Badie, D Brown, A Francois, N Hamada, S Jacob, C Li, M Sasaki, C Zervides, D Laurier, T Schneider, H Carpenter, H Essop, V Hande, M Kocemba, J Lopes, A Valenti, A Woerner","doi":"10.1177/01466453251412089","DOIUrl":"https://doi.org/10.1177/01466453251412089","url":null,"abstract":"The classification of harmful radiation-induced effects into 'stochastic' and 'deterministic' or 'cancer/heritable effects' and 'tissue reactions' has played a significant role in the recommendations of the International Commission on Radiological Protection (ICRP) over a number of decades. More recently, however, there has been a debate regarding the adequacy of the current scheme for classification of health effects with current scientific evidence. While these scientific aspects are discussed in greater detail in a parallel article, we will emphasise the practical importance of the classification itself here. The setting of dose limits is quite different for 'deterministic' and 'stochastic' effects. In the first case, provided reliable data regarding the threshold doses for radiation effects on a particular tissue are available, the dose limit is supposed to avoid harm altogether. With 'stochastic effects', the expected risks at the dose limit are supposed to be 'tolerable'. Below the dose limit, optimisation must be aimed for based on the 'prudent' assumption that the stochastic risks linearly depend on the dose and that there is no threshold. If the distinction between the two kinds of harmful effects is drawn into question, possible consequences for the system of radiological protection need to be considered, especially in the context of its aims as they currently apply, namely, 'to manage and control exposures to ionising radiation so that deterministic effects are prevented, and the risks of stochastic effects are reduced to the extent reasonably achievable'. It may be necessary, moreover, to discuss if and how the terminology used by ICRP (and others), in particular the terms 'deterministic effects' and 'tissue reactions', should continue to be used for the classification of radiation effects.","PeriodicalId":39551,"journal":{"name":"Annals of the ICRP","volume":" ","pages":"1466453251412089"},"PeriodicalIF":0.0,"publicationDate":"2026-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148036218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Automated dicentric scoring system in Singapore nuclear research and safety initiative. 在新加坡核研究和安全倡议的自动双中心评分系统。

Annals of the ICRP Pub Date : 2026-05-27 DOI: 10.1177/01466453251411985

J J W Yeo, V S T Goh, S X Teo, Z H Chew, C E L Chua

{"title":"Automated dicentric scoring system in Singapore nuclear research and safety initiative.","authors":"J J W Yeo, V S T Goh, S X Teo, Z H Chew, C E L Chua","doi":"10.1177/01466453251411985","DOIUrl":"https://doi.org/10.1177/01466453251411985","url":null,"abstract":"The dicentric chromosome assay (DCA) serves as the gold standard for quantifying ionising radiation exposure in individuals. However, the conventional manual scoring method for DCA is both time-consuming and mentally demanding. Consequently, numerous research groups and commercial entities are actively pursuing the integration of artificial intelligence to automate this process. In this study, we present methodologies and techniques employed at the Singapore Nuclear Research and Safety Initiative (SNRSI) for the development and optimisation of an in-house automated dicentric chromosome scoring tool. Our approach involves the utilisation of thresholding and watershed methods to identify chromosomes within a metaphase. Subsequently, these identified chromosomes are fed into a trained convolutional neural network (CNN) for classification and centromere number assignment. The cumulative centromere count is then calculated to determine the acceptance or rejection of the metaphase for scoring. This integration of advanced image processing techniques and machine learning algorithms would streamline and enhance the efficiency of the dicentric chromosome scoring at SNRSI.","PeriodicalId":39551,"journal":{"name":"Annals of the ICRP","volume":" ","pages":"1466453251411985"},"PeriodicalIF":0.0,"publicationDate":"2026-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148044044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Monte Carlo simulations of gamma ray scattering through concrete with embedded lead sheets. 通过嵌入铅板的混凝土的伽马射线散射的蒙特卡罗模拟。

Annals of the ICRP Pub Date : 2026-05-27 DOI: 10.1177/01466453251412099

A N Gentolea, A S Dizon, R L Cruzpero

{"title":"Monte Carlo simulations of gamma ray scattering through concrete with embedded lead sheets.","authors":"A N Gentolea, A S Dizon, R L Cruzpero","doi":"10.1177/01466453251412099","DOIUrl":"https://doi.org/10.1177/01466453251412099","url":null,"abstract":"With the hazard brought by highly energetic gamma radiation, it is necessary to increase the effectiveness of the gamma shields by considering their internal geometry or the arrangement of the materials within the shield. The study primarily analysed the effectiveness of the gamma shield based on its geometry to suggest a different configuration for radiation protection. The two geometries are horizontal and vertical embedded lead sheets inside the concrete slab. A total of 10,000 particles were simulated to traverse different set-ups of gamma shields using a Monte Carlo simulation programmed in the MATLAB desktop software. In the simulation, a random walk method was used within the shield to determine the scattering of photons. The results show that the concrete slab containing horizontal lead sheets compared with the concrete slab containing vertical lead sheets produced a difference of 0.06-1.01% in the number of transmitted photons and a difference of 1.15-3.85% in the average transmitted energies. Between the two configurations, the horizontal geometry of the embedded lead sheets is more effective in attenuating gamma scattering.","PeriodicalId":39551,"journal":{"name":"Annals of the ICRP","volume":" ","pages":"1466453251412099"},"PeriodicalIF":0.0,"publicationDate":"2026-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148036202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The importance of providing medium to long-term individual responses to radiation risk perception in areas affected by radiation disasters. 在受辐射灾害影响的地区，提供中期至长期个人辐射风险认知反应的重要性。

Annals of the ICRP Pub Date : 2026-05-27 DOI: 10.1177/01466453251412130

C Yamamoto, N Ito, T Oikawa, M Tsubokura

{"title":"The importance of providing medium to long-term individual responses to radiation risk perception in areas affected by radiation disasters.","authors":"C Yamamoto, N Ito, T Oikawa, M Tsubokura","doi":"10.1177/01466453251412130","DOIUrl":"https://doi.org/10.1177/01466453251412130","url":null,"abstract":"Radiation disasters cause direct radiation exposure and a variety of health issues, such as stress from evacuation life and prejudices based on incorrect perceptions of radiation. How the anxiety and risk perception of radiation exposure among residents living in the affected areas have changed is not well known. This study focuses on internal radiation exposure in infants and young children and parental radiation risk perception in Minamisoma City, which was impacted by the Fukushima Daiichi Nuclear Power Plant (FDNPP) accident. The study employs BABYSCAN data from July 2014 to November 2023. During the study period, 3936 infants underwent BABYSCAN testing, with no internal exposure to Cs134 or Cs137 detected in any of the participants. Surveys and counselling on food and water choices indicated a decrease in concerns about radiation contamination; however, anxiety about radiation among residents persisted. Additionally, there were concerns about the health effects related to the release of treated water from the FDNPP in 2023. The decline in participation rates in BABYSCAN and decreasing interest in radiation highlight the need for ongoing long-term risk communication and continued education for residents after radiation disasters.","PeriodicalId":39551,"journal":{"name":"Annals of the ICRP","volume":" ","pages":"1466453251412130"},"PeriodicalIF":0.0,"publicationDate":"2026-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148036276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Revisiting radiation dose-response for tissue reactions: with emphasis on diseases of the circulatory system. 重述组织反应的辐射剂量反应：重点是循环系统疾病。

Annals of the ICRP Pub Date : 2026-05-27 DOI: 10.1177/01466453251412092

H Ogino, N Ban

{"title":"Revisiting radiation dose-response for tissue reactions: with emphasis on diseases of the circulatory system.","authors":"H Ogino, N Ban","doi":"10.1177/01466453251412092","DOIUrl":"https://doi.org/10.1177/01466453251412092","url":null,"abstract":"In the system of radiological protection, tissue reactions are characterized by the presence of a threshold dose. While the threshold dose is defined as the estimated dose for 1% incidence (ED1), it may be complicated by substantial baseline levels for diseases that develop with aging in the absence of radiation exposure. ICRP Publication 118 states that ED1 refers to effects just starting to rise above the baseline levels in unirradiated, age-matched individuals and in the case of circulatory diseases, to a dose which would increase the already high natural incidence or mortality by only 1%. This implicitly assumes that radiation has a unique mechanism of action in inducing circulatory disease. However, circumstantial evidence suggests that radiation is likely to act jointly with other risk factors to promote atherosclerosis. If radiation-induced subclinical damage is added to that resulting from other risk factors, the threshold dose could be decreased depending on the extent of the joint effect. This phenomenon might be observed in age-related diseases that result from the accumulation of subclinical damage, and it is inferred that radiation accelerates the development of these diseases in a dose-dependent manner.","PeriodicalId":39551,"journal":{"name":"Annals of the ICRP","volume":" ","pages":"1466453251412092"},"PeriodicalIF":0.0,"publicationDate":"2026-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148036194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Are we safe? Exploring psychological factors affecting radiation risk perception of dwellers in old uranium mining quarters. 我们安全吗？探讨影响铀矿老矿区居民辐射风险认知的心理因素。

Annals of the ICRP Pub Date : 2026-05-26 DOI: 10.1177/01466453251412939

A R Melo, I Paiva, O Monteiro Gil, M C Reis, J M Palma-Oliveira, D R Martins, A Pereira, R C da Silva

{"title":"Are we safe? Exploring psychological factors affecting radiation risk perception of dwellers in old uranium mining quarters.","authors":"A R Melo, I Paiva, O Monteiro Gil, M C Reis, J M Palma-Oliveira, D R Martins, A Pereira, R C da Silva","doi":"10.1177/01466453251412939","DOIUrl":"https://doi.org/10.1177/01466453251412939","url":null,"abstract":"The central region of Portugal was an important mining zone of radioactive elements, relying on radium mining until 1944 and afterwards on uranium mining until 2000. With the dissolution of the Soviet Union in 1991, uranium mined by former member states flooded the market. Both the ensuing price drop and the exhaustion of mines led to the end of Portuguese uranium mining. Historic records show that economic and social benefits in that region overshadowed radiation risk perception. This article looks at ways to strengthen expertise and raise public awareness of radiological risk amongst dwellers in old uranium mining quarters. Some psychological factors are known to influence radiation risk perception and help explain the reaction of dwellers in homes built with uranium mining tailings. Exploration of these factors with a mental models approach and focus groups is necessary to raise the population's risk awareness, promote the adoption of safe behaviours regarding indoor radon risk and other ionising radiation risks, and answer the question of whether we are safe.","PeriodicalId":39551,"journal":{"name":"Annals of the ICRP","volume":" ","pages":"1466453251412939"},"PeriodicalIF":0.0,"publicationDate":"2026-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148036204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Statistical analysis of low dose rate mouse experiments with WGS technology and quantitative reproduction of mutation frequency using the whack-a-mole model. 采用WGS技术对低剂量率小鼠实验进行统计分析，并采用打地鼠模型定量再现突变频率。

Annals of the ICRP Pub Date : 2026-05-26 DOI: 10.1177/01466453251412150

H Toki, Y Gondo, A Uchimura, Y Tsunoyama, M Bando

引用次数: 0