Erika Arenas-Contreras , Laura Ariza-Teheran , Laura Borja-Egher , Omaira Diaz-Granados , Oriana Mora-Cartusciello , Lawren Thowinsson-Merizalde , Karina Cure-Aragón , Tania Acosta-Vergara , Edwin Guevara-Romero , Victor Florez-Garcia
{"title":"Síntomas de ansiedad y depresión en los trabajadores de la salud durante la pandemia por COVID-19 en un centro de salud en Barranquilla, Colombia","authors":"Erika Arenas-Contreras , Laura Ariza-Teheran , Laura Borja-Egher , Omaira Diaz-Granados , Oriana Mora-Cartusciello , Lawren Thowinsson-Merizalde , Karina Cure-Aragón , Tania Acosta-Vergara , Edwin Guevara-Romero , Victor Florez-Garcia","doi":"10.1016/j.psiq.2024.100505","DOIUrl":"10.1016/j.psiq.2024.100505","url":null,"abstract":"<div><h3>Introduction</h3><p>The spread of the pandemic in Colombian territory occurred heterogeneously, suggesting a potentially differential impact on the mental health of healthcare professionals who responded to the emergency.</p></div><div><h3>Objective</h3><p>To identify factors related to depressive and anxious symptoms in healthcare workers during the COVID-19 pandemic at a clinical center in the city of Barranquilla.</p></div><div><h3>Methodology</h3><p>We conducted a cross-sectional study involving 71 active healthcare workers in 2022. The Patient Health Questionnaire (PHQ-9) and the Generalized Anxiety Disorder scale (GAD-7) were utilized to estimate the prevalence of these mental disorders.</p></div><div><h3>Results</h3><p>We estimated a prevalence of depressive and anxious symptoms, mild or higher, at 18.3% (CI95% 10.1–29.3) and 21.1% (CI95% 12.3–33.4), respectively. Work experience, glove usage, gastrointestinal discomfort, and appetite disturbance were significantly associated with depressive symptoms, while loss of libido and appetite disturbance were linked to mild or higher anxious symptoms.</p></div><div><h3>Conclusions</h3><p>Depressive and anxious symptoms are common in the mental health of healthcare workers in pandemic contexts. Factors associated with these symptoms, such as the use of personal protective equipment and work experience, could be addressed through organizational management.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 4","pages":"Article 100505"},"PeriodicalIF":0.0,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142270963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jose Luis Estela-Zape , Diana Carolina Libreros-Chica , Lizeth Dayana Noreña-Buitrón , Jose Miguel Sierra-Olea
{"title":"Efectos terapéuticos de las plantas medicinales en los trastornos de ansiedad. Revisión exploratoria","authors":"Jose Luis Estela-Zape , Diana Carolina Libreros-Chica , Lizeth Dayana Noreña-Buitrón , Jose Miguel Sierra-Olea","doi":"10.1016/j.psiq.2024.100495","DOIUrl":"10.1016/j.psiq.2024.100495","url":null,"abstract":"<div><h3>Objective</h3><p>Describe the therapeutic effects of medicinal plants in anxiety disorders.</p></div><div><h3>Methods</h3><p>Scoping review conducted by the guidelines (PRISMA-ScR). Scopus, Web of Science and PubMed were searched for original articles, clinical trials and case series that explained the effects of medicinal plants used as anxiolytic agents in English and without publication date restrictions.</p></div><div><h3>Results</h3><p>A total of 735 records were initially identified. After eliminating duplicates and applying eligibility criteria, 11 studies were included that described the neurobiological actions of medicinal plants in relation to anxiety. The studies highlighted the benefit of plants by regulating neurotransmitters and various neurobiological systems, influencing the modulation of neuronal and neurochemical responses associated with the disorder.</p></div><div><h3>Conclusions</h3><p>Studies support the effectiveness of herbal therapy in reducing anxiety, but further research is required to validate its effectiveness, clinical safety, and potential drug interactions.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 4","pages":"Article 100495"},"PeriodicalIF":0.0,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142270964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna Giménez-Palomo , Lidia Ilzarbe , Eduard Vieta
{"title":"Eficacia, seguridad y tolerabilidad de cariprazina en el trastorno depresivo mayor: una revisión sistemática y aspectos prácticos","authors":"Anna Giménez-Palomo , Lidia Ilzarbe , Eduard Vieta","doi":"10.1016/j.psiq.2024.100494","DOIUrl":"10.1016/j.psiq.2024.100494","url":null,"abstract":"<div><p>Cariprazine is a new generation antipsychotic whose mechanism of action is based on partial agonism of dopamine D<sub>2</sub> and D<sub>3</sub> receptors, in addition to serotonin 5HT<sub>1A</sub> receptors. Its use has been approved by the Spanish Agency of Medicines and Medical Devices for the treatment of schizophrenia. However, the available literature has demonstrated its efficacy in the treatment of manic, mixed, and depressive episodes of bipolar disorder, all them approved indication in the United Sattes and several other countries. Likewise, there is currently evidence regarding the clinical efficacy, safety, and tolerability of cariprazine as an adjunctive treatment in major depressive disorder, which has granted this compound the approval by the Food and Drug Administration (FDA). While three clinical trials have shown negative results, two others have observed a significant reduction in depressive and anxiety symptoms, which has also been confirmed in a long-term open-label trial. Despite presenting a favorable adverse effect profile compared to other antipsychotics, cariprazine has been associated with akathisia and restlessness. Based on current evidence, the use of cariprazine as an adjunctive treatment to antidepressants may be beneficial in major depressive disorder. Future studies may address its efficacy in monotherapy, and its role in the prevention of depressive recurrences.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 4","pages":"Article 100494"},"PeriodicalIF":0.0,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142243597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clozapine delay results in poorer outcomes for treatment-resistant schizophrenia patients","authors":"Kalyani Rajalingham","doi":"10.1016/j.psiq.2024.100493","DOIUrl":"10.1016/j.psiq.2024.100493","url":null,"abstract":"<div><p>Treatment-resistant schizophrenia (TRS) is a condition where schizophrenia patients do not respond to at least 2 non-clozapine anti-psychotics administered in proper dosage and for a proper period of time. The typical treatment for TRS is clozapine but many alternatives are attempted prior to administering clozapine. Current research shows that the effectiveness of treatment with clozapine decreases with time in TRS patients; the longer a TRS patient waits to use clozapine, the less effective it is likely to be. In this paper, I review clozapine delay; clozapine treatment is effective if it happens within the first 3 years.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 4","pages":"Article 100493"},"PeriodicalIF":0.0,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142173267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luis Miguel Rojo-Bofill , Francisco Bellver Pradas , Pilar Benavent Rodríguez , Jose Carlos González-Piqueras , Vanessa Saiz Alarcón , Carmen Iranzo Tatay , Eduardo Jesús Aguilar García-Iturrospe
{"title":"Representación del riesgo suicida y su exploración en una simulación realizada por estudiantes de Medicina","authors":"Luis Miguel Rojo-Bofill , Francisco Bellver Pradas , Pilar Benavent Rodríguez , Jose Carlos González-Piqueras , Vanessa Saiz Alarcón , Carmen Iranzo Tatay , Eduardo Jesús Aguilar García-Iturrospe","doi":"10.1016/j.psiq.2024.100487","DOIUrl":"10.1016/j.psiq.2024.100487","url":null,"abstract":"<div><h3>Introduction</h3><p>Exploring suicide risk is a fundamental skill for medical professionals. However, university medical education typically does not include enough formal training in this area. Simulation has been used as a method for learning this skill, although most studies using this pedagogic tool focus on analysing changes in self-perceived capabilities and attitudes after receiving specific training on suicide.</p></div><div><h3>Methods</h3><p>A formative assessment task was carried out, consisting of recording a video in which groups of final-year medical students conducted a general psychiatric assessment with a simulated patient. The patient's diagnosis, suicide risk assessment, and exploratory questions were chosen by the students. Videos recorded over one term were studied. The chosen suicide risk assessment and exploratory questions regarding suicide risk were analysed independently and in relation to the chosen diagnosis.</p></div><div><h3>Results</h3><p>Out of 34 videos recorded, in 70% of those where suicide risk was explored, there was no suicidal ideation, and none had active suicidal ideation. Suicide risk was explored in 88% of the videos, but only 23.5% directly asked about the presence of suicidal ideation.</p></div><div><h3>Conclusions</h3><p>The task helped students integrate the importance of exploring suicide risk. The proportion of suicidal risk represented, and the exploratory questions, highlight the need to implement additional training interventions that focus on knowledge and stigma towards suicide.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 3","pages":"Article 100487"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141637645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clara Duque Casas, Elena González Rodríguez, Eduardo Delgado Parada
{"title":"Síndrome de Cotard tras la resección quirúrgica de un meningioma frontal derecho","authors":"Clara Duque Casas, Elena González Rodríguez, Eduardo Delgado Parada","doi":"10.1016/j.psiq.2024.100489","DOIUrl":"10.1016/j.psiq.2024.100489","url":null,"abstract":"<div><h3>Objective</h3><p>We present a case of Cotard's syndrome in a patient seen by the Liaison Psychiatry Team (EPE) after surgical resection of a meningioma. We carried out a historical review of the picture and its presentation in relation to structural brain damage.</p></div><div><h3>Clinical case</h3><p>Man in his thirties with no psychiatric history presented with insidious onset nihilistic delusional ideation with behavioral repercussions on the sixth day after neurosurgery for a right frontal meningioma. We clinically ruled out delirium.</p></div><div><h3>Results</h3><p>Antipsychotic and anxiolytic treatment was initiated, with progressive reduction until complete withdrawal on the tenth day due to behavioral improvement and partial encapsulation of the delirium that was maintained on an outpatient basis. The neuroradiological evolution was favorable and there were no metabolic or infectious complications. In the outpatient neuropsychological evaluation, cognitive difficulties compatible with the lesion were recorded, the presence of which could be prior to surgery.</p></div><div><h3>Conclusions</h3><p>Cotard's syndrome is a rare and under-researched condition that may be associated with supervening brain damage. The right hemisphere seems to play a leading role in perceptual integration and the relationship with the self, and its alterations have been related to the appearance of monothematic syndromes such as the one described here.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 3","pages":"Article 100489"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141630253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Belén Urbán Antón, Miguel Omaña Colmenares, Juan Fuertes Aparicio
{"title":"Depresión mayor resistente. Terapia electroconvulsiva versus esketamina. ¿Cuál debería ser el orden? A propósito de un caso","authors":"Belén Urbán Antón, Miguel Omaña Colmenares, Juan Fuertes Aparicio","doi":"10.1016/j.psiq.2024.100488","DOIUrl":"10.1016/j.psiq.2024.100488","url":null,"abstract":"<div><p>We present a case of a 73-year-old woman with a treatment- resistant depression to several antidepressants and electroconvulsive therapy, who improved significantly with intranasal esketamine showing a decrease in the MADRS score from 43 points (severe depression) to 18 points (mild depression) after 4 months of treatment. These results raise the question of whether, in elderly patients suffering a treatment- resistant depression and suicidal ideation, we should choose either electroconvulsive therapy or intranasal esketamine.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 3","pages":"Article 100488"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141637646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elena Blanco Martín, Mar González Testón, Susana Macayo Villalobos, Marta Ramírez Bravo
{"title":"Síndrome de hiperémesis cannábica. A propósito de un caso","authors":"Elena Blanco Martín, Mar González Testón, Susana Macayo Villalobos, Marta Ramírez Bravo","doi":"10.1016/j.psiq.2024.100490","DOIUrl":"10.1016/j.psiq.2024.100490","url":null,"abstract":"<div><p>A 23-year-old male daily <em>Cannabis</em> user came to the emergency department for cyclic hyperemesis and the need for compulsive hot showers for anxiolytic purposes. As probable antecedents, gastritis and dyspepsia related to <em>Cannabis</em> consumption. He has been evaluated by psychiatry for similar symptoms on several occasions and very high levels of anxiety.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 3","pages":"Article 100490"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141710542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marta Ramírez Bravo, Susana Macayo Villalobos, Mar González Testón, Elena Blanco Martín
{"title":"Conducta de «puerta giratoria» como compulsión. A propósito de un caso","authors":"Marta Ramírez Bravo, Susana Macayo Villalobos, Mar González Testón, Elena Blanco Martín","doi":"10.1016/j.psiq.2024.100492","DOIUrl":"10.1016/j.psiq.2024.100492","url":null,"abstract":"<div><p>This case report discusses treatment strategies for individuals exhibiting “revolving door” behaviors in mental health, focusing on a male patient diagnosed with obsessive-compulsive disorder and personality disorder. Despite consistent treatment, the patient displayed irregular follow-up and frequent visits to the emergency department. Following the identification of compulsion as the underlying issue, a psychoeducational intervention was introduced, leading to notable enhancements in the patient's condition by decreasing emergency department visits and enhancing participation in appointments with the Mental Health Team. This case underscores the significance of psychoeducational interventions in managing patients demonstrating “revolving door” behaviors in mental health settings.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 3","pages":"Article 100492"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141853187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}