{"title":"Síndrome anticolinérgico por biperideno, un complejo diagnóstico diferencial. A propósito de un caso","authors":"Ignacio Ramos Suárez, Antonio Martínez Cabezas","doi":"10.1016/j.psiq.2024.100443","DOIUrl":"10.1016/j.psiq.2024.100443","url":null,"abstract":"<div><p>Various pharmacological groups can trigger a series of acute dysautonomias that have the following features in common: muscle rigidity, hyperthermia, and autonomic dysfunction.</p><p>All these dysautonomias are grouped within the so-called drug-induced hyperthermic syndromes. They are characterized by a hypermetabolic state secondary to taking medications and other agents that alter neurotransmitter levels. Three of these syndromes: neuroleptic malignant syndrome, serotonin syndrome and anticholinergic syndrome are of special relevance in the psychiatric field since they are associated with the taking of drugs widely used by their specialists.</p><p>All of them have high morbidity and mortality, which is why they require a multidisciplinary approach to guarantee adequate diagnosis and therapeutic management.</p><p>For all these reasons, we present the case of a 49-year-old woman admitted to the Mental Health Hospitalization Unit as a result of catatonic symptoms who, on the third day of admission, developed symptoms of dysautonomia and hyperthermia concomitant with taking Olanzapine, citalopram and biperiden reason for which a complex differential diagnosis is proposed between: NMS, SS vs. AS.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 2","pages":"Article 100443"},"PeriodicalIF":0.0,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139875312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Raad-Sarabia , Maria Cardona-Blanco , Carmen Mendoza-Paternina , José Correa-Guerrero , Jorge Rico-Fontalvo , Rodrigo Daza-Arnedo , Zulay Mondol-Almeida , Jhonny Llinas-Rincon , Liseth Sierra-Torres , Juan Marrugo-Yunda
{"title":"Antidiabéticos orales y trastornos depresivos: ¿riesgo o protección?","authors":"Maria Raad-Sarabia , Maria Cardona-Blanco , Carmen Mendoza-Paternina , José Correa-Guerrero , Jorge Rico-Fontalvo , Rodrigo Daza-Arnedo , Zulay Mondol-Almeida , Jhonny Llinas-Rincon , Liseth Sierra-Torres , Juan Marrugo-Yunda","doi":"10.1016/j.psiq.2024.100441","DOIUrl":"10.1016/j.psiq.2024.100441","url":null,"abstract":"<div><h3>Introduction</h3><p>Diabetes mellitus and mood disorders are two entities that are intertwined with common pathophysiological mechanisms. Oral hypoglycemic agents are a fundamental pillar in obtaining adequate glucose control in diabetic individuals and, recently, the high prevalence of these two pathologies in the same patient have led clinical studies to focus on analyzing the effect of oral hypoglycemic agents in diabetics. patients with type 2 diabetes mellitus and depressive disorder.</p></div><div><h3>Objective</h3><p>To carry out a review of the available literature on hypoglycemic medication in the context of patients with diabetes mellitus and depressive disorder.</p></div><div><h3>Conclusions</h3><p>Although oral antidiabetics have been shown to have an antidepressant effect in certain experimental models, in clinical practice the evidence is scarce, but the lower risk of depression with certain antidiabetics is particularly noteworthy, leaving open the possibilities of future studies with the adequate nature that allows clarifying the effect of oral hypoglycemic agents in the population with diabetes mellitus and depressive disorder.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 1","pages":"Article 100441"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139458107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francisco J. Zamora-Rodríguez , María de la Luz Morales-Jiménez , Angel Benegas-Orrego
{"title":"Prevalencia de enfermedad psiquiátrica entre los suicidios consumados en la provincia de Badajoz en el periodo 2015-2017","authors":"Francisco J. Zamora-Rodríguez , María de la Luz Morales-Jiménez , Angel Benegas-Orrego","doi":"10.1016/j.psiq.2024.100446","DOIUrl":"https://doi.org/10.1016/j.psiq.2024.100446","url":null,"abstract":"<div><p>A study is carried out in 157 subjects who during the period established between July 01, 2015 and December 31, 2017 committed a consummated suicide in the province of Badajoz to investigate what percentage of consummated suicides had a history of mental pathology. The results indicate that there is a lower-than-expected relationship between the suicidal act and the presence of a personal psychiatric history, as these only appear in two-fifths of the sample. If they do exist, the most frequent diagnosis is depressive disorder and the most frequent treatment is antidepressants. These data contrast with other data collected in the literature that report much higher percentages of psychiatric pathology in subjects who commit suicide.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 1","pages":"Article 100446"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140031418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Belén Sánchez Martín-Moreno, José Ángel Gila Azañedo
{"title":"Coprolalia y copropraxia inducida por bupropión en un paciente autista y con trastorno obsesivo compulsivo","authors":"Belén Sánchez Martín-Moreno, José Ángel Gila Azañedo","doi":"10.1016/j.psiq.2024.100444","DOIUrl":"https://doi.org/10.1016/j.psiq.2024.100444","url":null,"abstract":"<div><p>The case is presented of a 41-year-old male, admitted since age 26 to the Residential and Rehabilitation Unit with the diagnoses of autism spectrum disorder and obsessive-compulsive disorder, and under treatment with fluvoxamine, valproic, topiramate, risperidone and clonazepam. After a period of stability, a picture compatible with a major depressive episode appear, which is treated with bupropion, in order to affect the symptoms of apathy and psychomotor slowness. There is a rapid recovery in two weeks, but he begins to present copropraxia and coprolalia, which he had never presented before. Bupropion is withdrawn and coprolalia disappears in two weeks, but he maintained some of these behaviors, so cyproterone acetate is prescribed to control them, with improvement in one week. Three months after withdrawal of bupropion, he reaches euthymia and no longer presented any sexual behavioral alteration, coprolalia or copropraxia. The literature confirms other cases of appearance of tics in patients treated with antidepressants for a depressive picture and comorbidity with obsessive-compulsive disorder, but almost none by the use of bupropion or with coprolalia and copropraxia.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 1","pages":"Article 100444"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140031419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Aliño-Dies, Daniel Sánchez-Reolid, Marta Monferrer, Jorge J. Ricarte, María J. Montes, Antonio Fernández-Caballero, Patricia Fernández-Sotos, Luz María González Gualda
{"title":"Programa de prevención del riesgo de suicidio «RENACE»","authors":"Maria Aliño-Dies, Daniel Sánchez-Reolid, Marta Monferrer, Jorge J. Ricarte, María J. Montes, Antonio Fernández-Caballero, Patricia Fernández-Sotos, Luz María González Gualda","doi":"10.1016/j.psiq.2024.100449","DOIUrl":"https://doi.org/10.1016/j.psiq.2024.100449","url":null,"abstract":"<div><p>Despite the fact that suicide is the leading cause of external death in Spain, there is no protocolized prevention or intervention plan at national level. The final aim of this study is the design, implementation and evaluation of a new suicide risk prevention program at the Albacete University Hospital Complex, called \"RENACE\". For this purpose, the sociodemographic and clinical profile of patients with suicidal ideation and behavior was described. The following results were obtained: the majority of patients were women (59%) and the most prevalent age group was 31 to 65 years old. Among the juvenile population, the predominant age range was 14 to 17 years. Regarding the clinical profile, the main diagnosis was trauma-related disorders and stress factors, followed by depressive disorders.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 1","pages":"Article 100449"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140031430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"La depresión como factor de riesgo de la demencia: fisiopatología y modelos preclínicos de estudio","authors":"Daniela Hernandez-Enseñat , Maylin Wong-Guerra , Jeney Ramírez-Sánchez , Luis Arturo Fonseca-Fonseca , Yanier Nuñez-Figueredo","doi":"10.1016/j.psiq.2023.100439","DOIUrl":"10.1016/j.psiq.2023.100439","url":null,"abstract":"<div><p>The increase in life expectancy has led to a rise in the incidence of chronic diseases, such as dementia. Treating the risk factors of dementia, such as depression, could help reduce its occurrence. However, antidepressant treatment has not proven effective in managing this symptom, thereby increasing the risk of dementia in the future. It is essential to investigate the causes and treatment of depression, and in this regard, the use of animal models is of great significance. This study aims to analyze the evidence supporting the relationship between depression and the risk of developing dementia, while also providing an update on the most relevant preclinical models for studying depression in rodents.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 1","pages":"Article 100439"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139013796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ping Wang, Chao Li, Marina Martin-Moratinos, Marcos Bella-Fernández, Pablo del Sol, Leticia Mallol, María Elena Hernández-Álvarez, Encarnación Donoso-Navarro, María Gil-Ligero, Silvia Rosado-Garcia, Antonio Sanchez-Lopez, Hilario Blasco-Fontecilla
{"title":"Biomarcadores sanguíneos, de orina y conductas autolesivas e intentos de suicidio repetidos en los adolescentes","authors":"Ping Wang, Chao Li, Marina Martin-Moratinos, Marcos Bella-Fernández, Pablo del Sol, Leticia Mallol, María Elena Hernández-Álvarez, Encarnación Donoso-Navarro, María Gil-Ligero, Silvia Rosado-Garcia, Antonio Sanchez-Lopez, Hilario Blasco-Fontecilla","doi":"10.1016/j.psiq.2024.100447","DOIUrl":"https://doi.org/10.1016/j.psiq.2024.100447","url":null,"abstract":"<div><p>There is partial evidence that elevated levels of blood β-endorphin are associated with suicidal addiction in adults, but hardly any data on adolescents. Blood β-endorphin, with an important role in addiction management mechanisms, can induce euphoria and happiness, reward and reinforce suicidal behavior. To test whether high repeaters of suicide attempts (5 or more suicide attempts) and self-injurious behaviors (20 or more episodes of self-injury) have higher biomarker levels, a sample of 43 patients aged 12-17 years attending the Psychiatric Emergency Department at the Hospital Universitario Puerta de Hierro Majadahonda is recruited. Ten present 5 or more suicide attempts, 35 present 20 or more self-injurious episodes and 10 present both characteristics, and most of the adolescents meet addiction criteria for self-injury and suicide. The results suggest that all patients with addiction to suicide also had addiction to self-injury. Blood ACTH, cortisol and β-endorphin and urine cortisol levels were very elevated, but did not differentiate heavy repeaters from the rest of the adolescents.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 1","pages":"Article 100447"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140031429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Aripiprazol: cuidado con la adicción patológica al juego","authors":"Pedro Moltó-Balado , Roxana Reverté-Gil","doi":"10.1016/j.psiq.2023.100440","DOIUrl":"https://doi.org/10.1016/j.psiq.2023.100440","url":null,"abstract":"<div><p>Aripiprazole is an antipsychotic drug used in the treatment of various psychiatric illnesses. Among its various adverse effects, one very rare but serious one stands out. The development of addictive behaviours such as pathological gambling is a situation that can lead to negative consequences in the personal, social and financial life of patients. A case on aripiprazole and pathological gambling is presented to highlight this rare effect.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 1","pages":"Article 100440"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139419149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sara Cabezas-Gutiérrez, Pablo Vázquez-Herrera, Batirtze Goitia-Aritxa
{"title":"Intersección de síntomas en el trastorno del espectro autista y trastornos psicóticos: a propósito de un caso","authors":"Sara Cabezas-Gutiérrez, Pablo Vázquez-Herrera, Batirtze Goitia-Aritxa","doi":"10.1016/j.psiq.2024.100442","DOIUrl":"https://doi.org/10.1016/j.psiq.2024.100442","url":null,"abstract":"<div><p>Autism spectrum disorder is a neurodevelopmental disorder with a current global prevalence of approximately 1%. It is common that the main symptoms of this disorder, such as deterioration in social interactions, restricted or atypical interests, and cognitive and verbal communication deficiencies, can be confused with symptoms of the psychotic sphere typical of schizophrenia. An adequate evaluation is necessary due that both entities can coexist with a variable prevalence of 12 to 50%. Moreover, both disorders can coexist with a variable prevalence of 12 to 50%. We present the clinical case of a woman who, at the age of 20, began follow-up in the mental health unit due to symptoms compatible with an obsessive-compulsive disorder along with a clinic characterized by apathy, anhedonia, abandonment of self-care and progressive functional deterioration. After several evaluation sessions, we diagnosed an autism spectrum disorder. We carry out a bibliographic review with which we conclude that the intersection of symptoms between autism and schizophrenia is common and clinical recommendations are provided to differentiate both clinical entities.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 1","pages":"Article 100442"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139908299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
María Dolores Rus Guerrero, Zaira Morales Domínguez, Yolanda Torrico Linares, Esperanza Torrico Linares
{"title":"Relación entre la capacidad adquirida y el riesgo suicida","authors":"María Dolores Rus Guerrero, Zaira Morales Domínguez, Yolanda Torrico Linares, Esperanza Torrico Linares","doi":"10.1016/j.psiq.2024.100448","DOIUrl":"https://doi.org/10.1016/j.psiq.2024.100448","url":null,"abstract":"<div><p>The Interpersonal Theory of Suicide states that acquired capability refers to the fact that repeated exposure to pain leads to habituation to these experiences, which is what leads the individual, if he or she also has suicidal ideation, to commit suicide. Therefore, the aim of this study is to analyze the differences in the acquired capability on the basis of the existence or not of suicidal risk. The results support those found in other studies, showing that there are statistically significant differences between those at risk and those not at risk, with those at risk having the highest mean scores. Therefore, the acquired capability variable is shown to be a variable highly related to suicidal risk.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 1","pages":"Article 100448"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140031420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}