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El deterioro cognitivo como factor de riesgo del delirium postoperatorio en la cirugía cardiaca basado en el Mini Mental State Examination, en personas mayores de 60 años: una revisión sistemática 根据 60 岁以上人群的迷你精神状态检查,认知障碍是心脏手术术后谵妄的风险因素:系统性综述。
Psiquiatria Biologica Pub Date : 2024-04-01 DOI: 10.1016/j.psiq.2024.100463
Rosanna Ujaldon-Martínez , Josep Deví-Bastida
{"title":"El deterioro cognitivo como factor de riesgo del delirium postoperatorio en la cirugía cardiaca basado en el Mini Mental State Examination, en personas mayores de 60 años: una revisión sistemática","authors":"Rosanna Ujaldon-Martínez ,&nbsp;Josep Deví-Bastida","doi":"10.1016/j.psiq.2024.100463","DOIUrl":"10.1016/j.psiq.2024.100463","url":null,"abstract":"<div><h3>Introduction</h3><p>Delirium is a neurocognitive disorder whose prevalence increases with age. Its incidence after cardiac surgery ranges between 11% and 52%. There are a large number of studies on the risk factors that affect the appearance of postoperative delirium in cardiac surgery, although most of them are oriented to physiological factors, often ignoring the possible relevance of neuropsychological aspects, such as cognitive impairment. The objective of this work was to analyze the influence of cognitive impairment as an independent risk factor (predictor) in the appearance of postoperative delirium based on the Mini Mental State Examination (MMSE), after cardiac surgery.</p></div><div><h3>Development</h3><p>A search was carried out in the databases PubMed, PsycInfo, Scopus and Web of Science. The search was limited to articles published between 2001 and 2022. 384 articles were obtained. Those that were repeated and not related to the topic were eliminated, leaving a total of 8 articles that met the selection criteria. This systematic review was carried out in accordance with the criteria of the PRISMA 2020 statement.</p></div><div><h3>Conclusions</h3><p>A statistically significant correlation was observed between the measure of cognitive impairment, the MMSE, and the different measures of postoperative delirium, in the majority of studies, so it can be concluded that possibly a mild degree of cognitive impairment may be a sufficient condition for the probability of appearance of postoperative delirium in cardiac surgeries in patients over 60 years of age. Therefore, assessment of cognitive impairment using MMSE before cardiac surgery could be useful to predict the development of postoperative delirium in people over 60 years of age.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 2","pages":"Article 100463"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140270682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long COVID: Clinical features and multidisciplinary approach 长COVID:临床特征和多学科方法
Psiquiatria Biologica Pub Date : 2024-04-01 DOI: 10.1016/j.psiq.2024.100471
A. Serrano García , J. Guerra Laso , L. Linares Álvarez , E. Turrado Valbuena , C. Vilella Martín , P. García Vázquez , C.M. Franch Pato
{"title":"Long COVID: Clinical features and multidisciplinary approach","authors":"A. Serrano García ,&nbsp;J. Guerra Laso ,&nbsp;L. Linares Álvarez ,&nbsp;E. Turrado Valbuena ,&nbsp;C. Vilella Martín ,&nbsp;P. García Vázquez ,&nbsp;C.M. Franch Pato","doi":"10.1016/j.psiq.2024.100471","DOIUrl":"https://doi.org/10.1016/j.psiq.2024.100471","url":null,"abstract":"<div><p>Although most of the patients affected by COVID-19 recover their health and return to their previous situation, some of them present symptoms that can last a long time after the acute illness. The main objective of this study is to assess the correlation between symptoms of long COVID and symptoms of central sensitization. Secondarily, it will try to describe the symptoms of long COVID and its correlation with alexithymia and depression.</p></div><div><h3>Methods</h3><p>Prospective observational study in real clinical conditions. Include consecutively those patients who present long COVID and complete multidisciplinary evaluation by a somatic specialist and a psychiatrist, together with a battery of questionnaires.</p></div><div><h3>Results</h3><p>The profile we found corresponds to a woman, in the middle of her fifth decade of life, with higher education and working, who passed the SARS-CoV-2 infection 1 year earlier, without requiring hospitalization and with a severe depressive disorder and alexithymia. We found an intermediate correlation (rho .665; <em>p</em> &lt; .01) between central sensitization questionnaire and the sum of symptoms of long COVID, as well as between the sum of symptoms presented and depression (rho .467; <em>p</em> &lt; .01) and not between the sum of symptoms and alexithymia (rho .151; <em>p</em> = .359).</p></div><div><h3>Conclusions</h3><p>Sensitization phenomena seem to be of notable importance in the symptoms of long COVID and present a symptomatic constellation characterized by fatigue, difficulty concentrating, and memory problems. Patients with persistent COVID present more severe depressive symptoms than they are capable of perceiving o express.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 2","pages":"Article 100471"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140649663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dietary patterns and dietary phytochemical index are associated with major depression disorder in females: A case–control study 膳食模式和膳食植物化学物指数与女性重度抑郁障碍有关:一项病例对照研究。
Psiquiatria Biologica Pub Date : 2024-03-25 DOI: 10.1016/j.psiq.2024.100470
Mohamad Amin Senobari , Maryam Khosravi , Negar sangsefidi , Mojtaba Mousavi Bazaz , Gity Sotoudeh
{"title":"Dietary patterns and dietary phytochemical index are associated with major depression disorder in females: A case–control study","authors":"Mohamad Amin Senobari ,&nbsp;Maryam Khosravi ,&nbsp;Negar sangsefidi ,&nbsp;Mojtaba Mousavi Bazaz ,&nbsp;Gity Sotoudeh","doi":"10.1016/j.psiq.2024.100470","DOIUrl":"10.1016/j.psiq.2024.100470","url":null,"abstract":"<div><h3>Background and aims</h3><p>Previous research has linked dietary patterns to depressive disorders, however, there are limited data on the association between the consumption of diets rich in phytochemicals and these disorders. This study aimed to investigate the association between dietary patterns and dietary phytochemical index (DPI) and major depression disorder (MDD) in Iranian females.</p></div><div><h3>Methods</h3><p>This case–control study was performed on 261 Iranian women (18–65 years, 87 cases, and 174 controls). Food intakes were assessed using a validated semi-quantitative food frequency questionnaire (FFQ). Depression was evaluated by a psychiatrist according to DSM IV criteria. We used factor analysis to extract dietary patterns and binary logistic regression to assess the relationship between dietary pattern scores and depression.</p></div><div><h3>Results</h3><p>Two major dietary patterns were identified: healthy and unhealthy patterns. After controlling for these variables, participants in the highest tertile of the healthy dietary pattern had significantly lower OR for major depression (OR<!--> <!-->=<!--> <!-->0.371; 95% CI: 0.168–0.819, <em>p</em> <!-->=.014). The second tertile of the unhealthy dietary pattern, compared with the lowest tertile had a higher OR for major depression (OR<!--> <!-->=<!--> <!-->3.162; 95% CI: 1.451–6.889, <em>p</em> <!-->=<!--> <!-->0.004). Also, women in the lowest tertile of DPI had a higher risk of major depression (OR 2.668; 95% CI 1.297, 5.491, <em>p</em> <!-->=.008) compared with those in the highest tertile.</p></div><div><h3>Conclusions</h3><p>We found that adherence to a healthy dietary pattern and high intakes of phytochemicals is associated with reduced risk, while an unhealthy dietary pattern is associated with an elevated risk of major depression.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 3","pages":"Article 100470"},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140402658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Consecuencias de la soledad y el aislamiento en las personas mayores: una revisión sistemática 老年人孤独和寂寞的后果:系统综述
Psiquiatria Biologica Pub Date : 2024-02-29 DOI: 10.1016/j.psiq.2024.100450
María Hervás Corral, Andrés Sánchez-Suricalday
{"title":"Consecuencias de la soledad y el aislamiento en las personas mayores: una revisión sistemática","authors":"María Hervás Corral,&nbsp;Andrés Sánchez-Suricalday","doi":"10.1016/j.psiq.2024.100450","DOIUrl":"https://doi.org/10.1016/j.psiq.2024.100450","url":null,"abstract":"<div><p>Loneliness and isolation in older people are concepts that have attracted attention in recent years due to their impact on the health and well-being of this social group. The objective of this work is to analyze the relationship between loneliness and isolation in older people with aspects related to their mental health, and examine if there are differences between both constructs. To this end, it was decided to carry out a systematic review following the PRISMA model, using the WOS and SCOPUS search engines. A total of 20 articles have been selected for the review. The results of the literature search confirm that loneliness affects anxiety, depression, perception of health or cognitive deterioration, in the same way as isolation. However, loneliness influences a greater number of variables, such as self-esteem. The conclusion reached is that loneliness negatively affects certain constructs related to the mental health of older people, which confirms the importance of developing preventive programs to alleviate its impact on this social group.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 2","pages":"Article 100450"},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140145102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Síndrome anticolinérgico por biperideno, un complejo diagnóstico diferencial. A propósito de un caso 哌啶导致的抗胆碱能综合征,一种复杂的鉴别诊断。病例报告
Psiquiatria Biologica Pub Date : 2024-02-14 DOI: 10.1016/j.psiq.2024.100443
Ignacio Ramos Suárez, Antonio Martínez Cabezas
{"title":"Síndrome anticolinérgico por biperideno, un complejo diagnóstico diferencial. A propósito de un caso","authors":"Ignacio Ramos Suárez,&nbsp;Antonio Martínez Cabezas","doi":"10.1016/j.psiq.2024.100443","DOIUrl":"10.1016/j.psiq.2024.100443","url":null,"abstract":"<div><p>Various pharmacological groups can trigger a series of acute dysautonomias that have the following features in common: muscle rigidity, hyperthermia, and autonomic dysfunction.</p><p>All these dysautonomias are grouped within the so-called drug-induced hyperthermic syndromes. They are characterized by a hypermetabolic state secondary to taking medications and other agents that alter neurotransmitter levels. Three of these syndromes: neuroleptic malignant syndrome, serotonin syndrome and anticholinergic syndrome are of special relevance in the psychiatric field since they are associated with the taking of drugs widely used by their specialists.</p><p>All of them have high morbidity and mortality, which is why they require a multidisciplinary approach to guarantee adequate diagnosis and therapeutic management.</p><p>For all these reasons, we present the case of a 49-year-old woman admitted to the Mental Health Hospitalization Unit as a result of catatonic symptoms who, on the third day of admission, developed symptoms of dysautonomia and hyperthermia concomitant with taking Olanzapine, citalopram and biperiden reason for which a complex differential diagnosis is proposed between: NMS, SS vs. AS.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 2","pages":"Article 100443"},"PeriodicalIF":0.0,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139875312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antidiabéticos orales y trastornos depresivos: ¿riesgo o protección? 口服抗糖尿病药与抑郁障碍:风险还是保护?
Psiquiatria Biologica Pub Date : 2024-01-01 DOI: 10.1016/j.psiq.2024.100441
Maria Raad-Sarabia , Maria Cardona-Blanco , Carmen Mendoza-Paternina , José Correa-Guerrero , Jorge Rico-Fontalvo , Rodrigo Daza-Arnedo , Zulay Mondol-Almeida , Jhonny Llinas-Rincon , Liseth Sierra-Torres , Juan Marrugo-Yunda
{"title":"Antidiabéticos orales y trastornos depresivos: ¿riesgo o protección?","authors":"Maria Raad-Sarabia ,&nbsp;Maria Cardona-Blanco ,&nbsp;Carmen Mendoza-Paternina ,&nbsp;José Correa-Guerrero ,&nbsp;Jorge Rico-Fontalvo ,&nbsp;Rodrigo Daza-Arnedo ,&nbsp;Zulay Mondol-Almeida ,&nbsp;Jhonny Llinas-Rincon ,&nbsp;Liseth Sierra-Torres ,&nbsp;Juan Marrugo-Yunda","doi":"10.1016/j.psiq.2024.100441","DOIUrl":"10.1016/j.psiq.2024.100441","url":null,"abstract":"<div><h3>Introduction</h3><p>Diabetes mellitus and mood disorders are two entities that are intertwined with common pathophysiological mechanisms. Oral hypoglycemic agents are a fundamental pillar in obtaining adequate glucose control in diabetic individuals and, recently, the high prevalence of these two pathologies in the same patient have led clinical studies to focus on analyzing the effect of oral hypoglycemic agents in diabetics. patients with type 2 diabetes mellitus and depressive disorder.</p></div><div><h3>Objective</h3><p>To carry out a review of the available literature on hypoglycemic medication in the context of patients with diabetes mellitus and depressive disorder.</p></div><div><h3>Conclusions</h3><p>Although oral antidiabetics have been shown to have an antidepressant effect in certain experimental models, in clinical practice the evidence is scarce, but the lower risk of depression with certain antidiabetics is particularly noteworthy, leaving open the possibilities of future studies with the adequate nature that allows clarifying the effect of oral hypoglycemic agents in the population with diabetes mellitus and depressive disorder.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 1","pages":"Article 100441"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139458107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalencia de enfermedad psiquiátrica entre los suicidios consumados en la provincia de Badajoz en el periodo 2015-2017 2015-2017 年期间巴达霍斯省自杀者中的精神病患病率。
Psiquiatria Biologica Pub Date : 2024-01-01 DOI: 10.1016/j.psiq.2024.100446
Francisco J. Zamora-Rodríguez , María de la Luz Morales-Jiménez , Angel Benegas-Orrego
{"title":"Prevalencia de enfermedad psiquiátrica entre los suicidios consumados en la provincia de Badajoz en el periodo 2015-2017","authors":"Francisco J. Zamora-Rodríguez ,&nbsp;María de la Luz Morales-Jiménez ,&nbsp;Angel Benegas-Orrego","doi":"10.1016/j.psiq.2024.100446","DOIUrl":"https://doi.org/10.1016/j.psiq.2024.100446","url":null,"abstract":"<div><p>A study is carried out in 157 subjects who during the period established between July 01, 2015 and December 31, 2017 committed a consummated suicide in the province of Badajoz to investigate what percentage of consummated suicides had a history of mental pathology. The results indicate that there is a lower-than-expected relationship between the suicidal act and the presence of a personal psychiatric history, as these only appear in two-fifths of the sample. If they do exist, the most frequent diagnosis is depressive disorder and the most frequent treatment is antidepressants. These data contrast with other data collected in the literature that report much higher percentages of psychiatric pathology in subjects who commit suicide.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 1","pages":"Article 100446"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140031418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Coprolalia y copropraxia inducida por bupropión en un paciente autista y con trastorno obsesivo compulsivo 一名自闭症和强迫症患者因安非他明引起的秽语和秽语障碍
Psiquiatria Biologica Pub Date : 2024-01-01 DOI: 10.1016/j.psiq.2024.100444
Belén Sánchez Martín-Moreno, José Ángel Gila Azañedo
{"title":"Coprolalia y copropraxia inducida por bupropión en un paciente autista y con trastorno obsesivo compulsivo","authors":"Belén Sánchez Martín-Moreno,&nbsp;José Ángel Gila Azañedo","doi":"10.1016/j.psiq.2024.100444","DOIUrl":"https://doi.org/10.1016/j.psiq.2024.100444","url":null,"abstract":"<div><p>The case is presented of a 41-year-old male, admitted since age 26 to the Residential and Rehabilitation Unit with the diagnoses of autism spectrum disorder and obsessive-compulsive disorder, and under treatment with fluvoxamine, valproic, topiramate, risperidone and clonazepam. After a period of stability, a picture compatible with a major depressive episode appear, which is treated with bupropion, in order to affect the symptoms of apathy and psychomotor slowness. There is a rapid recovery in two weeks, but he begins to present copropraxia and coprolalia, which he had never presented before. Bupropion is withdrawn and coprolalia disappears in two weeks, but he maintained some of these behaviors, so cyproterone acetate is prescribed to control them, with improvement in one week. Three months after withdrawal of bupropion, he reaches euthymia and no longer presented any sexual behavioral alteration, coprolalia or copropraxia. The literature confirms other cases of appearance of tics in patients treated with antidepressants for a depressive picture and comorbidity with obsessive-compulsive disorder, but almost none by the use of bupropion or with coprolalia and copropraxia.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 1","pages":"Article 100444"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140031419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Programa de prevención del riesgo de suicidio «RENACE» 预防自杀风险计划 "RENACE"。
Psiquiatria Biologica Pub Date : 2024-01-01 DOI: 10.1016/j.psiq.2024.100449
Maria Aliño-Dies, Daniel Sánchez-Reolid, Marta Monferrer, Jorge J. Ricarte, María J. Montes, Antonio Fernández-Caballero, Patricia Fernández-Sotos, Luz María González Gualda
{"title":"Programa de prevención del riesgo de suicidio «RENACE»","authors":"Maria Aliño-Dies,&nbsp;Daniel Sánchez-Reolid,&nbsp;Marta Monferrer,&nbsp;Jorge J. Ricarte,&nbsp;María J. Montes,&nbsp;Antonio Fernández-Caballero,&nbsp;Patricia Fernández-Sotos,&nbsp;Luz María González Gualda","doi":"10.1016/j.psiq.2024.100449","DOIUrl":"https://doi.org/10.1016/j.psiq.2024.100449","url":null,"abstract":"<div><p>Despite the fact that suicide is the leading cause of external death in Spain, there is no protocolized prevention or intervention plan at national level. The final aim of this study is the design, implementation and evaluation of a new suicide risk prevention program at the Albacete University Hospital Complex, called \"RENACE\". For this purpose, the sociodemographic and clinical profile of patients with suicidal ideation and behavior was described. The following results were obtained: the majority of patients were women (59%) and the most prevalent age group was 31 to 65 years old. Among the juvenile population, the predominant age range was 14 to 17 years. Regarding the clinical profile, the main diagnosis was trauma-related disorders and stress factors, followed by depressive disorders.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 1","pages":"Article 100449"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140031430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
La depresión como factor de riesgo de la demencia: fisiopatología y modelos preclínicos de estudio 抑郁症是痴呆症的风险因素:病理生理学和临床前研究模型。
Psiquiatria Biologica Pub Date : 2024-01-01 DOI: 10.1016/j.psiq.2023.100439
Daniela Hernandez-Enseñat , Maylin Wong-Guerra , Jeney Ramírez-Sánchez , Luis Arturo Fonseca-Fonseca , Yanier Nuñez-Figueredo
{"title":"La depresión como factor de riesgo de la demencia: fisiopatología y modelos preclínicos de estudio","authors":"Daniela Hernandez-Enseñat ,&nbsp;Maylin Wong-Guerra ,&nbsp;Jeney Ramírez-Sánchez ,&nbsp;Luis Arturo Fonseca-Fonseca ,&nbsp;Yanier Nuñez-Figueredo","doi":"10.1016/j.psiq.2023.100439","DOIUrl":"10.1016/j.psiq.2023.100439","url":null,"abstract":"<div><p>The increase in life expectancy has led to a rise in the incidence of chronic diseases, such as dementia. Treating the risk factors of dementia, such as depression, could help reduce its occurrence. However, antidepressant treatment has not proven effective in managing this symptom, thereby increasing the risk of dementia in the future. It is essential to investigate the causes and treatment of depression, and in this regard, the use of animal models is of great significance. This study aims to analyze the evidence supporting the relationship between depression and the risk of developing dementia, while also providing an update on the most relevant preclinical models for studying depression in rodents.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 1","pages":"Article 100439"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139013796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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