Psiquiatria Biologica最新文献_第10页

Respiratory depression caused by low dose of olanzapine: A case report 低剂量奥氮平致呼吸抑制1例

Psiquiatria Biologica Pub Date : 2023-05-01 DOI: 10.1016/j.psiq.2023.100412

Masatoshi Inoue

引用次数: 0

Estabilidad diagnóstica y evolución en esquizofrenia 精神分裂症的诊断稳定性和演变

Psiquiatria Biologica Pub Date : 2023-05-01 DOI: 10.1016/j.psiq.2023.100414

Nora Palomar-Ciria , Enrique Baca-García

引用次数: 0

Delayed-onset posttraumatic stress disorder with response to methylphenidate 迟发性创伤后应激障碍伴哌甲酯反应

Psiquiatria Biologica Pub Date : 2023-05-01 DOI: 10.1016/j.psiq.2023.100397

María-José Alvarez , Ricardo López-Escribano , Ana Marzán , Luis Alonso-Alvarez

{"title":"Delayed-onset posttraumatic stress disorder with response to methylphenidate","authors":"María-José Alvarez , Ricardo López-Escribano , Ana Marzán , Luis Alonso-Alvarez","doi":"10.1016/j.psiq.2023.100397","DOIUrl":"https://doi.org/10.1016/j.psiq.2023.100397","url":null,"abstract":"<div><h3>Introduction</h3><p>Posttraumatic stress disorder<span> (PTSD) is extremely frequent in war veterans and has been widely studied. However, the efficacy of currently available pharmacological and psychotherapeutic treatments of war PTSD and other causes of PTSD is very limited.</span></p></div><div><h3>Method</h3><p>We present a case of war PTSD with delayed expression, with a good response to complementation with methylphenidate<span> after a failed treatment with venlafaxine<span> and risperidone.</span></span></p></div><div><h3>Results</h3><p><span><span><span>We review the role of dopamine in the pathophysiology of PTSD and the scarce studies in the treatment of PTSD with </span>dopaminergic </span>drugs<span> that show an improvement in re-experimentation and in affective symptoms, especially anhedonia and </span></span>cognitive impairment.</p></div><div><h3>Conclusions</h3><p>We conclude that the use of methylphenidate and other dopaminergic drugs can be a promising treatment for PTSD, a high prevalent disease with a high resistance to treatment, for which we encourage the use of large sample studies.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"30 2","pages":"Article 100397"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49841733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chatbots and psychiatry: Beware of hallucinations of artificial intelligence 聊天机器人和精神病学:当心人工智能的幻觉

Psiquiatria Biologica Pub Date : 2023-01-01 DOI: 10.1016/j.psiq.2023.100394

Jesús Enrique Ibáñez Vizoso , Agustín Bermejo Pastor

引用次数: 0

Olanzapina, 26 años: situación actual, conocimientos, actitudes y prácticas de uso entre los psiquiatras españoles 奥氮平，26岁:西班牙精神科医生的现状、知识、态度和使用做法

Psiquiatria Biologica Pub Date : 2023-01-01 DOI: 10.1016/j.psiq.2022.100391

Jairo M. Gonzalez-Diaz , Miquel Bernardo

{"title":"Olanzapina, 26 años: situación actual, conocimientos, actitudes y prácticas de uso entre los psiquiatras españoles","authors":"Jairo M. Gonzalez-Diaz , Miquel Bernardo","doi":"10.1016/j.psiq.2022.100391","DOIUrl":"https://doi.org/10.1016/j.psiq.2022.100391","url":null,"abstract":"<div><p>Olanzapine, a second-generation antipsychotic marketed in Europe since late 1996, continues to be one of the most widely used molecules in Spain today. However, its high rate of adverse metabolic events and its use in some clinical settings are still controversial. The objective of this study was to explore the knowledge, attitudes, and practices of use of this medication among Spanish psychiatrists. A self-filled questionnaire was designed and distributed. Dosage, experience, and trends of use in different contexts were explored, as well as future expectations. Data were tabulated and a descriptive analysis was performed. 129 practicing psychiatrists throughout the Spanish territory participated in the study, with an average age of 45.46 years (SD=9.57) and a female: male ratio of 1.04:1. After more than 25 years on the market, Olanzapine continues to be an antipsychotic widely used in different clinical settings, both in Schizophrenia and other mental disorders (preferably at doses between 5 and 10 mg/day). Spanish psychiatrists are familiar with the need to establish pharmacological and non-pharmacological strategies for the metabolic control of patients using this drug.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"30 1","pages":"Article 100391"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49868833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relación entre la cantidad y el tipo de alcohol (destilado versus fermentado) consumido y el riesgo de aparición de deterioro cognitivo compatible con un síndrome demencial en personas mayores de 60 años: revisión sistemática 酒精消费的数量和类型(蒸馏酒与发酵酒)与60岁以上人群出现与痴呆综合征一致的认知障碍风险之间的关系:系统综述

Psiquiatria Biologica Pub Date : 2023-01-01 DOI: 10.1016/j.psiq.2023.100395

Josep Deví-Bastida , Helena Puig-Martel , Santiago Llana-Cortés , Alexandra García-Guix , M. Teresa Abellán-Vidal , M. Dolores López-Villegas

{"title":"Relación entre la cantidad y el tipo de alcohol (destilado versus fermentado) consumido y el riesgo de aparición de deterioro cognitivo compatible con un síndrome demencial en personas mayores de 60 años: revisión sistemática","authors":"Josep Deví-Bastida , Helena Puig-Martel , Santiago Llana-Cortés , Alexandra García-Guix , M. Teresa Abellán-Vidal , M. Dolores López-Villegas","doi":"10.1016/j.psiq.2023.100395","DOIUrl":"https://doi.org/10.1016/j.psiq.2023.100395","url":null,"abstract":"<div><h3>Introduction</h3><p>Alcohol is the most consumed substance in Western culture and its consumption is a causal factor in more than 200 diseases and disorders. The objective was to determine the relationship between the amount and type of alcohol (distilled or fermented) consumed, in individuals over 60 years of age, and the appearance of cognitive deterioration compatible with a dementia syndrome as a consequence of excessive and prolonged consumption.</p></div><div><h3>Development</h3><p>Search in Medline, PsycInfo and Web of Science databases. The search was limited to articles published between 2010 and 2021, based on the combination of various terms related to dementia, alcohol consumption and type, and old age. 157 articles were obtained, those repeated and those not related to the topic were eliminated, leaving a total of 9 articles. This systematic review has been carried out in accordance with the criteria of the PRISMA statement.</p></div><div><h3>Conclusions</h3><p>Most of the studies found (7 out of 9) suggested an association between alcohol consumption and the onset of dementia. Regarding the type of beverages, everything and the objectification of some inconclusive results, in general it is suggested that the consumption of wine (fermented beverage) is associated with a decrease of cognitive deterioration and the consumption of liquor (distilled beverage) to a increased cognitive decline; the role of beer is not clear. Therefore, it can be concluded that the association between alcohol consumption and greater or lesser cognitive impairment depends both on excessive and prolonged consumption, as well as on the type of beverages consumed (distilled or fermented).</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"30 1","pages":"Article 100395"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49868832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Utilidad diagnóstica de la secuenciación de segunda y tercera generación en pacientes con discapacidad intelectual: revisión rápida 第二代和第三代测序对智障患者的诊断价值：快速回顾

Psiquiatria Biologica Pub Date : 2023-01-01 DOI: 10.1016/j.psiq.2023.100392

Hugo H. Abarca-Barriga , Flor Vásquez-Sotomayor

{"title":"Utilidad diagnóstica de la secuenciación de segunda y tercera generación en pacientes con discapacidad intelectual: revisión rápida","authors":"Hugo H. Abarca-Barriga , Flor Vásquez-Sotomayor","doi":"10.1016/j.psiq.2023.100392","DOIUrl":"https://doi.org/10.1016/j.psiq.2023.100392","url":null,"abstract":"<div><h3>Introduction</h3><p>Some populations have an intellectual disability frequency of nearly 18%. Among, the diverse genetic causes are single nucleotide variants and copy number variations, detected with second-generation sequencing and chromosomal microarray analysis, respectively. Nevertheless, other variants such as structural variants, trinucleotide repeat or imprinting disorders, cannot be detected by these tests and require different specific techniques. Third-generation sequencing have a power of found all variants. The purpose is to stablish the benefits of using third generation sequencing above second-generation sequencing in the diagnosis of patient with intellectual disability.</p></div><div><h3>Material and methods</h3><p>A rapid systematic review was performed on the Medline using thesaurus terms MESH of “intellectual disability” and “second-generation sequencing”; as well as using the term “third-generation sequencing”.</p></div><div><h3>Results</h3><p>31 articles were selected in total. Of those, nine used third-generation sequencing in patients with previously genomic test, and founded structural variants in 40% of cases, all these variants were corroborated with other gold standard tests. Twenty-two studies used second-generation sequencing (n = 22) and showed through metanalysis, that 29,8% and 9,2% of these cases are due a single nucleotide variant and copy number variations, respectively.</p></div><div><h3>Conclusions</h3><p>Third-generation sequencing can find structural variants, uniparental disomies, trinucleotide repeat and single nucleotide variation. Therefore, it would allow a broader and better study of the etiology of intellectual disability. Nevertheless, more research with larger representative samples in patients and healthy population is needed.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"30 1","pages":"Article 100392"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49830961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Are there still endogenous and reactive depressions? Clinical notes from a refractory Cotard Syndrome with a de novo post-ECT dissociative episode 是否还有内源性和反应性抑郁?难治性科塔尔综合征伴电痉挛后解离发作的临床记录

Psiquiatria Biologica Pub Date : 2022-09-01 DOI: 10.1016/j.psiq.2022.100379

Alexandre P. Gomes , Liliana C. Gomes , Eduardo Gonçalves , Emanuel L. Santos

{"title":"Are there still endogenous and reactive depressions? Clinical notes from a refractory Cotard Syndrome with a de novo post-ECT dissociative episode","authors":"Alexandre P. Gomes , Liliana C. Gomes , Eduardo Gonçalves , Emanuel L. Santos","doi":"10.1016/j.psiq.2022.100379","DOIUrl":"10.1016/j.psiq.2022.100379","url":null,"abstract":"<div><p><span><span>Cotard syndrome is a mysterious and severe disorder. Many therapeutic interventions are reported as potentially efficacious mostly when an underlying psychotic depression<span> or melancholia is diagnosed. However, the classification of depression has long been a contentious issue. Even though the major guide for therapeutic choice is severity, the binary model between endogenous and reactive depression is still widely employed in clinical practice. These considerations impact most clearly in in-between presentations. The authors present the case of R., a 64 year old woman, who was admitted with a major depressive episode with psychotic features, captured as a Cotard-like syndrome. After a two-months inpatient period and apparent clinical remission with high dose antidepressants and </span></span>antipsychotic combination, she displayed an acute worsening leading to a re-admission just a day </span>after discharge<span>. The management in this second admission was tortuous, due to SARS-CoV2 related contingencies, the refractoriness of the presentation and iatrogenic intercurrences. The authors expose the course and treatment options employed, while reflecting on the question endogenous v. reactive, concluding that even seemingly clear clinical presentations may resist our different conceptualizations.</span></p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"29 3","pages":"Article 100379"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126676411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Treatment of Catatonia in a Young Adult with COVID-19 Infection; Case Report and Review of the Literature on Electroconvulsive Therapy During the Covid-19 Pandemic 青年人COVID-19感染后紧张症的治疗新冠肺炎大流行期间电休克治疗病例报告及文献综述

Psiquiatria Biologica Pub Date : 2022-09-01 DOI: 10.1016/j.psiq.2022.100368

Emily Aquadro, Lorelys Arroyo Rivera, Alexandra Dodd

引用次数: 1

La respuesta placebo en el consumo de cocaína: una revisión sistemática 可卡因使用中的安慰剂反应:一项系统综述

Psiquiatria Biologica Pub Date : 2022-09-01 DOI: 10.1016/j.psiq.2022.100370

Estela Rueda, José Francisco Navarro

{"title":"La respuesta placebo en el consumo de cocaína: una revisión sistemática","authors":"Estela Rueda, José Francisco Navarro","doi":"10.1016/j.psiq.2022.100370","DOIUrl":"10.1016/j.psiq.2022.100370","url":null,"abstract":"<div><p>The study of the placebo response in the modulation of the effects of drugs of abuse is receiving increasing interest. The aim of the present systematic review is to examine the placebo response in cocaine use. For this purpose, we conducted a literature search in the Web of Science, PubMed and Scopus databases, which has been complemented with a manual search, finally including a total of 15 papers between both searches. The results indicate higher responses after cocaine administration than after placebo; moreover, it has been found that exposure to cocaine-related stimuli generates an expectancy in people with a history of cocaine use, which plays a crucial role in both objective and subjective induced responses (mainly increased heart rate and blood pressure and increased craving), which are not as pronounced in subjects without a history of cocaine use. These results suggest that this phenomenon is mediated by a conditioning history of the consuming participants that determines the response to the drug even before ingestion. Knowledge of the functioning of the placebo response in drug use allows the identification of markers of the disease state, thus allowing the implementation better intervention strategies</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"29 3","pages":"Article 100370"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1134593422000203/pdfft?md5=eeeeb61724a5fca4d8b3c82e4e256c50&pid=1-s2.0-S1134593422000203-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132070321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0