Merve Şahin Can, Sinan Altunöz, Hediye Hilal Yapıcı, Hayriye Baykan
{"title":"Development of frontotemporal dementia in a patient followed up with late-onset bipolar disorder: A case report","authors":"Merve Şahin Can, Sinan Altunöz, Hediye Hilal Yapıcı, Hayriye Baykan","doi":"10.1016/j.psiq.2024.100473","DOIUrl":"10.1016/j.psiq.2024.100473","url":null,"abstract":"<div><p>Frontotemporal dementia is an insidious neurodegenerative clinical syndrome characterized by progressive deficits in behavior, executive function, and language. The initial clinical presentation of some patients with FTD may resemble bipolar mood disorder.In this case, it was planned to diagnose FTD in addition to the emergence of behavioral and cognitive problems in the patient followed up with bipolar mood disorder and to discuss the difficulties experienced in the treatment. In 2017, he was diagnosed with bipolar mood disorder due to loud speech, irritability, thinking that he was cast under a spell, increased spending, driving fast, swearing at relatives. He was followed up with lithium, olanzapine and quetiapine treatment, and he benefited from the treatment. The diagnosis of frontotemporal dementia was considered in the patient who underwent brain diffusion MRI and PET CT in December 2020, upon the onset of the complaint of forgetfulness. Informed consent was obtained from the patient and his relatives.In conclusion, in our case who was followed up with bipolar disorder, a co-diagnosis of frontotemporal dementia was made with the emergence of memory and behavioral pathologies in the later follow-ups. With the diagnosis of FTD, the severity of the patient's manic episodes, clinical presentation, and treatment response changed. Therefore, FTD should be considered in the differential diagnosis of patients who are followed up with bipolar disorder and subsequently have clinical changes.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 2","pages":"Article 100473"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140781522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dulcinea Vega , Francisco J. Acosta , Pedro Saavedra , Guillermo Pírez
{"title":"No adherencia en pacientes con esquizofrenia y trastorno esquizoafectivo. Estudio prospectivo de variables asociadas y posibles subtipos","authors":"Dulcinea Vega , Francisco J. Acosta , Pedro Saavedra , Guillermo Pírez","doi":"10.1016/j.psiq.2024.100466","DOIUrl":"10.1016/j.psiq.2024.100466","url":null,"abstract":"<div><h3>Introduction</h3><p>The rate of non-adherence to treatment in schizophrenia is between 40 and 50%. The scarcity of consistently identified variables associated with nonadherence could be due to real heterogeneity among nonadherent patients.</p></div><div><h3>Objectives</h3><p>Evaluate the prevalence of non-adherence in patients with schizophrenia or schizoaffective disorder. Evaluate the possible subtypes of non-adherence according to intentionality.</p></div><div><h3>Methodology</h3><p>110 consecutively admitted patients diagnosed with schizophrenia and schizoaffective disorder were included. They were evaluated during admission and six months after hospital discharge. Sociodemographic, clinical, psychopathological, and treatment-related variables were included. Adherence was defined as the concurrence of adherence to antipsychotic treatment and follow-up. The subtype of non-adherence was established according to the main reason for non-adherence.</p></div><div><h3>Results</h3><p>Non-adherence was found in 58.2% of the patients. Low socioeconomic status, cannabis use, nonadherence as a reason for relapse and admission, and severity of symptoms were independently associated with nonadherence. Low educational level, poorer treatment knowledge at six months, and use of non-psychiatric treatment at six months were independently associated with the subtype of unintentional non-adherence.</p></div><div><h3>Conclusions</h3><p>A high percentage of patients with schizophrenia and schizoaffective disorder do not show adherence after hospital discharge. There seem to be subtypes of non-adherence according to the intention, which suggests the need for a differentiated approach.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 2","pages":"Article 100466"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140273977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Romina González Vázquez , Manuel Lorenzo López Reboiro , Peter F. Armanious , Estefany Díaz de Argueta , Keivan Kianifar Aguilar , María Teresa Alves Pérez , José López Castro
{"title":"Levels of depression and quality of life in patients hospitalized for moderate–severe COVID-19 in a regional hospital: INTER-MONF study","authors":"Romina González Vázquez , Manuel Lorenzo López Reboiro , Peter F. Armanious , Estefany Díaz de Argueta , Keivan Kianifar Aguilar , María Teresa Alves Pérez , José López Castro","doi":"10.1016/j.psiq.2024.100468","DOIUrl":"10.1016/j.psiq.2024.100468","url":null,"abstract":"<div><h3>Background and objectives</h3><p>Coronavirus disease (COVID-19) is an infectious disease that causes both physical and mental sequelae. The aim of the present study was to evaluate the quality of life and the level of depression in post-COVID-19 patients using the SF-36 Questionnaire (SF-36) and the Beck depression inventory (BDI) and to compare it with the quality of life of the general population for the same sex and age group.</p></div><div><h3>Methods</h3><p>A cohort, observational, and prospective study was designed with the survivors of the group of 115 patients hospitalized at Hospital Público de Monforte to whom the SF-36 and BDI were performed.</p></div><div><h3>Results</h3><p>60 patients responded to the questionnaires (mean age 65.24 (±<!--> <!-->15.49) years and 40% women). In the SF-36, the summary of the physical and mental component was, respectively, 47.71(±<!--> <!-->8.48) and 47.25(±<!--> <!-->9.39). Women have lower scores than men in half of the components of the SF-36. The probability of depression inferred by SF-36 was 28% and applying BDI results were 81.67% of the sample were not depressed, 8.33% were mild–moderate depressed, 6,67% were moderate–severe depressed, and 3.33% were severely depressed.</p></div><div><h3>Conclusions</h3><p>Patients who have suffered COVID-19 predisposes to a higher frequency of depression as well as to a worse quality of life in terms of both physical and mental health. This should serve to raise awareness of the follow-up of patients with long COVID-19 in order to prevent, as far as possible, a decrease in their quality of life.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 2","pages":"Article 100468"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140407777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"El deterioro cognitivo como factor de riesgo del delirium postoperatorio en la cirugía cardiaca basado en el Mini Mental State Examination, en personas mayores de 60 años: una revisión sistemática","authors":"Rosanna Ujaldon-Martínez , Josep Deví-Bastida","doi":"10.1016/j.psiq.2024.100463","DOIUrl":"10.1016/j.psiq.2024.100463","url":null,"abstract":"<div><h3>Introduction</h3><p>Delirium is a neurocognitive disorder whose prevalence increases with age. Its incidence after cardiac surgery ranges between 11% and 52%. There are a large number of studies on the risk factors that affect the appearance of postoperative delirium in cardiac surgery, although most of them are oriented to physiological factors, often ignoring the possible relevance of neuropsychological aspects, such as cognitive impairment. The objective of this work was to analyze the influence of cognitive impairment as an independent risk factor (predictor) in the appearance of postoperative delirium based on the Mini Mental State Examination (MMSE), after cardiac surgery.</p></div><div><h3>Development</h3><p>A search was carried out in the databases PubMed, PsycInfo, Scopus and Web of Science. The search was limited to articles published between 2001 and 2022. 384 articles were obtained. Those that were repeated and not related to the topic were eliminated, leaving a total of 8 articles that met the selection criteria. This systematic review was carried out in accordance with the criteria of the PRISMA 2020 statement.</p></div><div><h3>Conclusions</h3><p>A statistically significant correlation was observed between the measure of cognitive impairment, the MMSE, and the different measures of postoperative delirium, in the majority of studies, so it can be concluded that possibly a mild degree of cognitive impairment may be a sufficient condition for the probability of appearance of postoperative delirium in cardiac surgeries in patients over 60 years of age. Therefore, assessment of cognitive impairment using MMSE before cardiac surgery could be useful to predict the development of postoperative delirium in people over 60 years of age.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 2","pages":"Article 100463"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140270682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Serrano García , J. Guerra Laso , L. Linares Álvarez , E. Turrado Valbuena , C. Vilella Martín , P. García Vázquez , C.M. Franch Pato
{"title":"Long COVID: Clinical features and multidisciplinary approach","authors":"A. Serrano García , J. Guerra Laso , L. Linares Álvarez , E. Turrado Valbuena , C. Vilella Martín , P. García Vázquez , C.M. Franch Pato","doi":"10.1016/j.psiq.2024.100471","DOIUrl":"https://doi.org/10.1016/j.psiq.2024.100471","url":null,"abstract":"<div><p>Although most of the patients affected by COVID-19 recover their health and return to their previous situation, some of them present symptoms that can last a long time after the acute illness. The main objective of this study is to assess the correlation between symptoms of long COVID and symptoms of central sensitization. Secondarily, it will try to describe the symptoms of long COVID and its correlation with alexithymia and depression.</p></div><div><h3>Methods</h3><p>Prospective observational study in real clinical conditions. Include consecutively those patients who present long COVID and complete multidisciplinary evaluation by a somatic specialist and a psychiatrist, together with a battery of questionnaires.</p></div><div><h3>Results</h3><p>The profile we found corresponds to a woman, in the middle of her fifth decade of life, with higher education and working, who passed the SARS-CoV-2 infection 1 year earlier, without requiring hospitalization and with a severe depressive disorder and alexithymia. We found an intermediate correlation (rho .665; <em>p</em> < .01) between central sensitization questionnaire and the sum of symptoms of long COVID, as well as between the sum of symptoms presented and depression (rho .467; <em>p</em> < .01) and not between the sum of symptoms and alexithymia (rho .151; <em>p</em> = .359).</p></div><div><h3>Conclusions</h3><p>Sensitization phenomena seem to be of notable importance in the symptoms of long COVID and present a symptomatic constellation characterized by fatigue, difficulty concentrating, and memory problems. Patients with persistent COVID present more severe depressive symptoms than they are capable of perceiving o express.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 2","pages":"Article 100471"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140649663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dietary patterns and dietary phytochemical index are associated with major depression disorder in females: A case–control study","authors":"Mohamad Amin Senobari , Maryam Khosravi , Negar sangsefidi , Mojtaba Mousavi Bazaz , Gity Sotoudeh","doi":"10.1016/j.psiq.2024.100470","DOIUrl":"10.1016/j.psiq.2024.100470","url":null,"abstract":"<div><h3>Background and aims</h3><p>Previous research has linked dietary patterns to depressive disorders, however, there are limited data on the association between the consumption of diets rich in phytochemicals and these disorders. This study aimed to investigate the association between dietary patterns and dietary phytochemical index (DPI) and major depression disorder (MDD) in Iranian females.</p></div><div><h3>Methods</h3><p>This case–control study was performed on 261 Iranian women (18–65 years, 87 cases, and 174 controls). Food intakes were assessed using a validated semi-quantitative food frequency questionnaire (FFQ). Depression was evaluated by a psychiatrist according to DSM IV criteria. We used factor analysis to extract dietary patterns and binary logistic regression to assess the relationship between dietary pattern scores and depression.</p></div><div><h3>Results</h3><p>Two major dietary patterns were identified: healthy and unhealthy patterns. After controlling for these variables, participants in the highest tertile of the healthy dietary pattern had significantly lower OR for major depression (OR<!--> <!-->=<!--> <!-->0.371; 95% CI: 0.168–0.819, <em>p</em> <!-->=.014). The second tertile of the unhealthy dietary pattern, compared with the lowest tertile had a higher OR for major depression (OR<!--> <!-->=<!--> <!-->3.162; 95% CI: 1.451–6.889, <em>p</em> <!-->=<!--> <!-->0.004). Also, women in the lowest tertile of DPI had a higher risk of major depression (OR 2.668; 95% CI 1.297, 5.491, <em>p</em> <!-->=.008) compared with those in the highest tertile.</p></div><div><h3>Conclusions</h3><p>We found that adherence to a healthy dietary pattern and high intakes of phytochemicals is associated with reduced risk, while an unhealthy dietary pattern is associated with an elevated risk of major depression.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 3","pages":"Article 100470"},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140402658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Consecuencias de la soledad y el aislamiento en las personas mayores: una revisión sistemática","authors":"María Hervás Corral, Andrés Sánchez-Suricalday","doi":"10.1016/j.psiq.2024.100450","DOIUrl":"https://doi.org/10.1016/j.psiq.2024.100450","url":null,"abstract":"<div><p>Loneliness and isolation in older people are concepts that have attracted attention in recent years due to their impact on the health and well-being of this social group. The objective of this work is to analyze the relationship between loneliness and isolation in older people with aspects related to their mental health, and examine if there are differences between both constructs. To this end, it was decided to carry out a systematic review following the PRISMA model, using the WOS and SCOPUS search engines. A total of 20 articles have been selected for the review. The results of the literature search confirm that loneliness affects anxiety, depression, perception of health or cognitive deterioration, in the same way as isolation. However, loneliness influences a greater number of variables, such as self-esteem. The conclusion reached is that loneliness negatively affects certain constructs related to the mental health of older people, which confirms the importance of developing preventive programs to alleviate its impact on this social group.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 2","pages":"Article 100450"},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140145102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Síndrome anticolinérgico por biperideno, un complejo diagnóstico diferencial. A propósito de un caso","authors":"Ignacio Ramos Suárez, Antonio Martínez Cabezas","doi":"10.1016/j.psiq.2024.100443","DOIUrl":"10.1016/j.psiq.2024.100443","url":null,"abstract":"<div><p>Various pharmacological groups can trigger a series of acute dysautonomias that have the following features in common: muscle rigidity, hyperthermia, and autonomic dysfunction.</p><p>All these dysautonomias are grouped within the so-called drug-induced hyperthermic syndromes. They are characterized by a hypermetabolic state secondary to taking medications and other agents that alter neurotransmitter levels. Three of these syndromes: neuroleptic malignant syndrome, serotonin syndrome and anticholinergic syndrome are of special relevance in the psychiatric field since they are associated with the taking of drugs widely used by their specialists.</p><p>All of them have high morbidity and mortality, which is why they require a multidisciplinary approach to guarantee adequate diagnosis and therapeutic management.</p><p>For all these reasons, we present the case of a 49-year-old woman admitted to the Mental Health Hospitalization Unit as a result of catatonic symptoms who, on the third day of admission, developed symptoms of dysautonomia and hyperthermia concomitant with taking Olanzapine, citalopram and biperiden reason for which a complex differential diagnosis is proposed between: NMS, SS vs. AS.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 2","pages":"Article 100443"},"PeriodicalIF":0.0,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139875312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Raad-Sarabia , Maria Cardona-Blanco , Carmen Mendoza-Paternina , José Correa-Guerrero , Jorge Rico-Fontalvo , Rodrigo Daza-Arnedo , Zulay Mondol-Almeida , Jhonny Llinas-Rincon , Liseth Sierra-Torres , Juan Marrugo-Yunda
{"title":"Antidiabéticos orales y trastornos depresivos: ¿riesgo o protección?","authors":"Maria Raad-Sarabia , Maria Cardona-Blanco , Carmen Mendoza-Paternina , José Correa-Guerrero , Jorge Rico-Fontalvo , Rodrigo Daza-Arnedo , Zulay Mondol-Almeida , Jhonny Llinas-Rincon , Liseth Sierra-Torres , Juan Marrugo-Yunda","doi":"10.1016/j.psiq.2024.100441","DOIUrl":"10.1016/j.psiq.2024.100441","url":null,"abstract":"<div><h3>Introduction</h3><p>Diabetes mellitus and mood disorders are two entities that are intertwined with common pathophysiological mechanisms. Oral hypoglycemic agents are a fundamental pillar in obtaining adequate glucose control in diabetic individuals and, recently, the high prevalence of these two pathologies in the same patient have led clinical studies to focus on analyzing the effect of oral hypoglycemic agents in diabetics. patients with type 2 diabetes mellitus and depressive disorder.</p></div><div><h3>Objective</h3><p>To carry out a review of the available literature on hypoglycemic medication in the context of patients with diabetes mellitus and depressive disorder.</p></div><div><h3>Conclusions</h3><p>Although oral antidiabetics have been shown to have an antidepressant effect in certain experimental models, in clinical practice the evidence is scarce, but the lower risk of depression with certain antidiabetics is particularly noteworthy, leaving open the possibilities of future studies with the adequate nature that allows clarifying the effect of oral hypoglycemic agents in the population with diabetes mellitus and depressive disorder.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 1","pages":"Article 100441"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139458107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francisco J. Zamora-Rodríguez , María de la Luz Morales-Jiménez , Angel Benegas-Orrego
{"title":"Prevalencia de enfermedad psiquiátrica entre los suicidios consumados en la provincia de Badajoz en el periodo 2015-2017","authors":"Francisco J. Zamora-Rodríguez , María de la Luz Morales-Jiménez , Angel Benegas-Orrego","doi":"10.1016/j.psiq.2024.100446","DOIUrl":"https://doi.org/10.1016/j.psiq.2024.100446","url":null,"abstract":"<div><p>A study is carried out in 157 subjects who during the period established between July 01, 2015 and December 31, 2017 committed a consummated suicide in the province of Badajoz to investigate what percentage of consummated suicides had a history of mental pathology. The results indicate that there is a lower-than-expected relationship between the suicidal act and the presence of a personal psychiatric history, as these only appear in two-fifths of the sample. If they do exist, the most frequent diagnosis is depressive disorder and the most frequent treatment is antidepressants. These data contrast with other data collected in the literature that report much higher percentages of psychiatric pathology in subjects who commit suicide.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 1","pages":"Article 100446"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140031418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}