Constanza Vera-Varela , María Luisa Barrigón , Enrique Baca-García
{"title":"Concordancia del autorreporte y la valoración clínica de la ideación suicida","authors":"Constanza Vera-Varela , María Luisa Barrigón , Enrique Baca-García","doi":"10.1016/j.psiq.2024.100510","DOIUrl":"10.1016/j.psiq.2024.100510","url":null,"abstract":"<div><h3>Background</h3><div>Thoughts of suicide and/or death usually precede suicide attempts and suicide deaths. We study the agreement in passive suicidal ideation between reports made by clinicians during an outpatient mental health service and patients’ online self-reports.</div></div><div><h3>Methodology</h3><div>Between 2014 and 2016, during routine psychiatric and psychological appointments in the outpatient mental-health facilities affiliated with the Fundación Jiménez Díaz Hospital in Madrid, wish of death was assessed in 25.358 patients.</div><div>Within 24 hours of this assessment, 648 patients completed a self-report in which they were asked about the presence of passive suicidal ideation. We used cluster analysis to determine the clinical profile of a population of patients according to the agreement between reports made by clinicians and self-reported information.</div></div><div><h3>Results</h3><div>A low level of agreement (kappa<!--> <!-->=<!--> <!-->0.072) was found between clinicians and patients, as 56.4% (n<!--> <!-->=<!--> <!-->366) of clinicians’ reports classified as containing no death-related ideas, although on self-report the patient did state that they had passive suicidal ideation. In this group, two clusters (cluster 2 y 4) were found to have shared characteristics: female sex, middle age, cohabitation, active employment, no history of suicidal behavior, and diagnosis of neurotic, stress-related, and somatoform disorders. Additionally, cluster 4 patients self-reported sleep disturbances, less appetite, poor treatment adherence, and aggressiveness.</div></div><div><h3>Conclusions</h3><div>We found low agreement between patients’ self-reports and clinician assessments regarding the passive suicidal ideation. Self-report may be useful in suicide risk assessment as a complementary method, that allows to generate a confidential space that could reduce the problem of underreporting of passive suicidal ideation.</div></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 4","pages":"Article 100510"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142420159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Belén Resa-Pérez , Andrea Jiménez-Mayoral , Vanessa Gladys Velasquez-Acebey , Filip Damian Budny , Georgina Badia i Realp , Salvador Miret-Fallada , María Irigoyen-Otiñano
{"title":"Case report. Pregnancy in women with an eating disorder","authors":"Belén Resa-Pérez , Andrea Jiménez-Mayoral , Vanessa Gladys Velasquez-Acebey , Filip Damian Budny , Georgina Badia i Realp , Salvador Miret-Fallada , María Irigoyen-Otiñano","doi":"10.1016/j.psiq.2024.100511","DOIUrl":"10.1016/j.psiq.2024.100511","url":null,"abstract":"<div><h3>Introduction</h3><div>Pregnancy has been described as a period of symptomatic stability for women diagnosed with eating disorder (ED). However, a poor control of alimentary symptoms before and during pregnancy is associated with higher risk of adverse effects during childbirth and the postpartum period. A case report is presented and a bibliographic review is carried out.</div></div><div><h3>Methods</h3><div>The authors take the case of a 33-year-old woman diagnosed with anorexia nervosa during adolescence, who becomes pregnant at the age of 30. A non-systematic review was carried out using the Pubmed database using keywords [eating disorder] AND [pregnancy]. Studies of more than 5 years were excluded. The patient's informed consent was obtained. This work complies with the agreements of the Declaration of Helsinki.</div></div><div><h3>Results</h3><div>Eutocic delivery was carried out without incidents. Currently, the baby is 5 months old, his weight is adjusted to his age and his neurodevelopment is normal. Although the patient denies restrictions or purgative behaviors, she has lost weight in postpartum and has recovered her pre-pregnancy body mass index. No major affective symptoms have been observed in this period.</div></div><div><h3>Discussion/Conclusions</h3><div>Pregnancy and postpartum period constitute periods of greater vulnerability in terms of eating symptoms in patients with EDs. Emphasis should be placed on a multidisciplinary approach with the aim of avoiding the appearance of associated risk factors both for the mother and the baby.</div></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 4","pages":"Article 100511"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142420157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Erika Arenas-Contreras , Laura Ariza-Teheran , Laura Borja-Egher , Omaira Diaz-Granados , Oriana Mora-Cartusciello , Lawren Thowinsson-Merizalde , Karina Cure-Aragón , Tania Acosta-Vergara , Edwin Guevara-Romero , Victor Florez-Garcia
{"title":"Síntomas de ansiedad y depresión en los trabajadores de la salud durante la pandemia por COVID-19 en un centro de salud en Barranquilla, Colombia","authors":"Erika Arenas-Contreras , Laura Ariza-Teheran , Laura Borja-Egher , Omaira Diaz-Granados , Oriana Mora-Cartusciello , Lawren Thowinsson-Merizalde , Karina Cure-Aragón , Tania Acosta-Vergara , Edwin Guevara-Romero , Victor Florez-Garcia","doi":"10.1016/j.psiq.2024.100505","DOIUrl":"10.1016/j.psiq.2024.100505","url":null,"abstract":"<div><h3>Introduction</h3><p>The spread of the pandemic in Colombian territory occurred heterogeneously, suggesting a potentially differential impact on the mental health of healthcare professionals who responded to the emergency.</p></div><div><h3>Objective</h3><p>To identify factors related to depressive and anxious symptoms in healthcare workers during the COVID-19 pandemic at a clinical center in the city of Barranquilla.</p></div><div><h3>Methodology</h3><p>We conducted a cross-sectional study involving 71 active healthcare workers in 2022. The Patient Health Questionnaire (PHQ-9) and the Generalized Anxiety Disorder scale (GAD-7) were utilized to estimate the prevalence of these mental disorders.</p></div><div><h3>Results</h3><p>We estimated a prevalence of depressive and anxious symptoms, mild or higher, at 18.3% (CI95% 10.1–29.3) and 21.1% (CI95% 12.3–33.4), respectively. Work experience, glove usage, gastrointestinal discomfort, and appetite disturbance were significantly associated with depressive symptoms, while loss of libido and appetite disturbance were linked to mild or higher anxious symptoms.</p></div><div><h3>Conclusions</h3><p>Depressive and anxious symptoms are common in the mental health of healthcare workers in pandemic contexts. Factors associated with these symptoms, such as the use of personal protective equipment and work experience, could be addressed through organizational management.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 4","pages":"Article 100505"},"PeriodicalIF":0.0,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142270963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jose Luis Estela-Zape , Diana Carolina Libreros-Chica , Lizeth Dayana Noreña-Buitrón , Jose Miguel Sierra-Olea
{"title":"Efectos terapéuticos de las plantas medicinales en los trastornos de ansiedad. Revisión exploratoria","authors":"Jose Luis Estela-Zape , Diana Carolina Libreros-Chica , Lizeth Dayana Noreña-Buitrón , Jose Miguel Sierra-Olea","doi":"10.1016/j.psiq.2024.100495","DOIUrl":"10.1016/j.psiq.2024.100495","url":null,"abstract":"<div><h3>Objective</h3><p>Describe the therapeutic effects of medicinal plants in anxiety disorders.</p></div><div><h3>Methods</h3><p>Scoping review conducted by the guidelines (PRISMA-ScR). Scopus, Web of Science and PubMed were searched for original articles, clinical trials and case series that explained the effects of medicinal plants used as anxiolytic agents in English and without publication date restrictions.</p></div><div><h3>Results</h3><p>A total of 735 records were initially identified. After eliminating duplicates and applying eligibility criteria, 11 studies were included that described the neurobiological actions of medicinal plants in relation to anxiety. The studies highlighted the benefit of plants by regulating neurotransmitters and various neurobiological systems, influencing the modulation of neuronal and neurochemical responses associated with the disorder.</p></div><div><h3>Conclusions</h3><p>Studies support the effectiveness of herbal therapy in reducing anxiety, but further research is required to validate its effectiveness, clinical safety, and potential drug interactions.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 4","pages":"Article 100495"},"PeriodicalIF":0.0,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142270964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna Giménez-Palomo , Lidia Ilzarbe , Eduard Vieta
{"title":"Eficacia, seguridad y tolerabilidad de cariprazina en el trastorno depresivo mayor: una revisión sistemática y aspectos prácticos","authors":"Anna Giménez-Palomo , Lidia Ilzarbe , Eduard Vieta","doi":"10.1016/j.psiq.2024.100494","DOIUrl":"10.1016/j.psiq.2024.100494","url":null,"abstract":"<div><p>Cariprazine is a new generation antipsychotic whose mechanism of action is based on partial agonism of dopamine D<sub>2</sub> and D<sub>3</sub> receptors, in addition to serotonin 5HT<sub>1A</sub> receptors. Its use has been approved by the Spanish Agency of Medicines and Medical Devices for the treatment of schizophrenia. However, the available literature has demonstrated its efficacy in the treatment of manic, mixed, and depressive episodes of bipolar disorder, all them approved indication in the United Sattes and several other countries. Likewise, there is currently evidence regarding the clinical efficacy, safety, and tolerability of cariprazine as an adjunctive treatment in major depressive disorder, which has granted this compound the approval by the Food and Drug Administration (FDA). While three clinical trials have shown negative results, two others have observed a significant reduction in depressive and anxiety symptoms, which has also been confirmed in a long-term open-label trial. Despite presenting a favorable adverse effect profile compared to other antipsychotics, cariprazine has been associated with akathisia and restlessness. Based on current evidence, the use of cariprazine as an adjunctive treatment to antidepressants may be beneficial in major depressive disorder. Future studies may address its efficacy in monotherapy, and its role in the prevention of depressive recurrences.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 4","pages":"Article 100494"},"PeriodicalIF":0.0,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142243597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clozapine delay results in poorer outcomes for treatment-resistant schizophrenia patients","authors":"Kalyani Rajalingham","doi":"10.1016/j.psiq.2024.100493","DOIUrl":"10.1016/j.psiq.2024.100493","url":null,"abstract":"<div><p>Treatment-resistant schizophrenia (TRS) is a condition where schizophrenia patients do not respond to at least 2 non-clozapine anti-psychotics administered in proper dosage and for a proper period of time. The typical treatment for TRS is clozapine but many alternatives are attempted prior to administering clozapine. Current research shows that the effectiveness of treatment with clozapine decreases with time in TRS patients; the longer a TRS patient waits to use clozapine, the less effective it is likely to be. In this paper, I review clozapine delay; clozapine treatment is effective if it happens within the first 3 years.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 4","pages":"Article 100493"},"PeriodicalIF":0.0,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142173267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luis Miguel Rojo-Bofill , Francisco Bellver Pradas , Pilar Benavent Rodríguez , Jose Carlos González-Piqueras , Vanessa Saiz Alarcón , Carmen Iranzo Tatay , Eduardo Jesús Aguilar García-Iturrospe
{"title":"Representación del riesgo suicida y su exploración en una simulación realizada por estudiantes de Medicina","authors":"Luis Miguel Rojo-Bofill , Francisco Bellver Pradas , Pilar Benavent Rodríguez , Jose Carlos González-Piqueras , Vanessa Saiz Alarcón , Carmen Iranzo Tatay , Eduardo Jesús Aguilar García-Iturrospe","doi":"10.1016/j.psiq.2024.100487","DOIUrl":"10.1016/j.psiq.2024.100487","url":null,"abstract":"<div><h3>Introduction</h3><p>Exploring suicide risk is a fundamental skill for medical professionals. However, university medical education typically does not include enough formal training in this area. Simulation has been used as a method for learning this skill, although most studies using this pedagogic tool focus on analysing changes in self-perceived capabilities and attitudes after receiving specific training on suicide.</p></div><div><h3>Methods</h3><p>A formative assessment task was carried out, consisting of recording a video in which groups of final-year medical students conducted a general psychiatric assessment with a simulated patient. The patient's diagnosis, suicide risk assessment, and exploratory questions were chosen by the students. Videos recorded over one term were studied. The chosen suicide risk assessment and exploratory questions regarding suicide risk were analysed independently and in relation to the chosen diagnosis.</p></div><div><h3>Results</h3><p>Out of 34 videos recorded, in 70% of those where suicide risk was explored, there was no suicidal ideation, and none had active suicidal ideation. Suicide risk was explored in 88% of the videos, but only 23.5% directly asked about the presence of suicidal ideation.</p></div><div><h3>Conclusions</h3><p>The task helped students integrate the importance of exploring suicide risk. The proportion of suicidal risk represented, and the exploratory questions, highlight the need to implement additional training interventions that focus on knowledge and stigma towards suicide.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 3","pages":"Article 100487"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141637645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clara Duque Casas, Elena González Rodríguez, Eduardo Delgado Parada
{"title":"Síndrome de Cotard tras la resección quirúrgica de un meningioma frontal derecho","authors":"Clara Duque Casas, Elena González Rodríguez, Eduardo Delgado Parada","doi":"10.1016/j.psiq.2024.100489","DOIUrl":"10.1016/j.psiq.2024.100489","url":null,"abstract":"<div><h3>Objective</h3><p>We present a case of Cotard's syndrome in a patient seen by the Liaison Psychiatry Team (EPE) after surgical resection of a meningioma. We carried out a historical review of the picture and its presentation in relation to structural brain damage.</p></div><div><h3>Clinical case</h3><p>Man in his thirties with no psychiatric history presented with insidious onset nihilistic delusional ideation with behavioral repercussions on the sixth day after neurosurgery for a right frontal meningioma. We clinically ruled out delirium.</p></div><div><h3>Results</h3><p>Antipsychotic and anxiolytic treatment was initiated, with progressive reduction until complete withdrawal on the tenth day due to behavioral improvement and partial encapsulation of the delirium that was maintained on an outpatient basis. The neuroradiological evolution was favorable and there were no metabolic or infectious complications. In the outpatient neuropsychological evaluation, cognitive difficulties compatible with the lesion were recorded, the presence of which could be prior to surgery.</p></div><div><h3>Conclusions</h3><p>Cotard's syndrome is a rare and under-researched condition that may be associated with supervening brain damage. The right hemisphere seems to play a leading role in perceptual integration and the relationship with the self, and its alterations have been related to the appearance of monothematic syndromes such as the one described here.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 3","pages":"Article 100489"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141630253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Belén Urbán Antón, Miguel Omaña Colmenares, Juan Fuertes Aparicio
{"title":"Depresión mayor resistente. Terapia electroconvulsiva versus esketamina. ¿Cuál debería ser el orden? A propósito de un caso","authors":"Belén Urbán Antón, Miguel Omaña Colmenares, Juan Fuertes Aparicio","doi":"10.1016/j.psiq.2024.100488","DOIUrl":"10.1016/j.psiq.2024.100488","url":null,"abstract":"<div><p>We present a case of a 73-year-old woman with a treatment- resistant depression to several antidepressants and electroconvulsive therapy, who improved significantly with intranasal esketamine showing a decrease in the MADRS score from 43 points (severe depression) to 18 points (mild depression) after 4 months of treatment. These results raise the question of whether, in elderly patients suffering a treatment- resistant depression and suicidal ideation, we should choose either electroconvulsive therapy or intranasal esketamine.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"31 3","pages":"Article 100488"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141637646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}