Psiquiatria Biologica最新文献_第6页

La catatonia. Diagnóstico y tratamiento a propósito de un caso 我能找到它。对一个病例的诊断和治疗

Psiquiatria Biologica Pub Date : 2023-05-01 DOI: 10.1016/j.psiq.2023.100396

Pablo Vázquez-Herrera , Sara Cabezas-Gutierrez , Batirtze Goitia-Aritxa

引用次数: 0

Tiaprida, una alternativa de tratamiento en el trastorno por uso de alcohol: a propósito de un caso Tiaprida，酒精使用障碍的另一种治疗方法：针对一个病例

Psiquiatria Biologica Pub Date : 2023-05-01 DOI: 10.1016/j.psiq.2023.100393

Luz María González Gualda , Rocío Sáez Povedano , Paloma Cano-Ruiz , Miguel Barberán Navalón

{"title":"Tiaprida, una alternativa de tratamiento en el trastorno por uso de alcohol: a propósito de un caso","authors":"Luz María González Gualda , Rocío Sáez Povedano , Paloma Cano-Ruiz , Miguel Barberán Navalón","doi":"10.1016/j.psiq.2023.100393","DOIUrl":"https://doi.org/10.1016/j.psiq.2023.100393","url":null,"abstract":"<div><h3>Objective</h3><p>Present a clinical case report on the use of tiapride for alcohol detoxification in a patient with a diagnosis of severe alcohol use disorder 303.90 (F10.20).</p></div><div><h3>Clinical case report</h3><p>50 year-old female, under follow-up in the Addictive Behavior Unit from September 2016 to present, with diagnoses of adjustment disorder 309.4 (F43.25)</p><p>Mixed disturbance of emotions or behavior, severe alcohol use disorder 303.90 (F10.20) and severe decompensation, who is treated with tiapride.</p></div><div><h3>Results</h3><p>The studies consulted demonstrate the efficacy and safety of tiapride for alcohol withdrawal syndrome in both outpatient and inpatient settings, in monotherapy or in polytherapy with benzodiazepines and/or antiepileptics, being also used in agitation and/or psychotic symptomatology.</p></div><div><h3>Conclusions</h3><p>In alcohol withdrawal syndrome, tiapride has been found to be effective and can even be considered as an adjunctive treatment to benzodiazepines or anticonvulsants. With a view to the future, pharmacogenetics affecting alcohol use disorder should be taken into account, so that individualized personalized therapy could benefit from fewer adverse effects.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49841731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Respiratory depression caused by low dose of olanzapine: A case report 低剂量奥氮平致呼吸抑制1例

Psiquiatria Biologica Pub Date : 2023-05-01 DOI: 10.1016/j.psiq.2023.100412

Masatoshi Inoue

引用次数: 0

Estabilidad diagnóstica y evolución en esquizofrenia 精神分裂症的诊断稳定性和演变

Psiquiatria Biologica Pub Date : 2023-05-01 DOI: 10.1016/j.psiq.2023.100414

Nora Palomar-Ciria , Enrique Baca-García

引用次数: 0

Delayed-onset posttraumatic stress disorder with response to methylphenidate 迟发性创伤后应激障碍伴哌甲酯反应

Psiquiatria Biologica Pub Date : 2023-05-01 DOI: 10.1016/j.psiq.2023.100397

María-José Alvarez , Ricardo López-Escribano , Ana Marzán , Luis Alonso-Alvarez

{"title":"Delayed-onset posttraumatic stress disorder with response to methylphenidate","authors":"María-José Alvarez , Ricardo López-Escribano , Ana Marzán , Luis Alonso-Alvarez","doi":"10.1016/j.psiq.2023.100397","DOIUrl":"https://doi.org/10.1016/j.psiq.2023.100397","url":null,"abstract":"<div><h3>Introduction</h3><p>Posttraumatic stress disorder<span> (PTSD) is extremely frequent in war veterans and has been widely studied. However, the efficacy of currently available pharmacological and psychotherapeutic treatments of war PTSD and other causes of PTSD is very limited.</span></p></div><div><h3>Method</h3><p>We present a case of war PTSD with delayed expression, with a good response to complementation with methylphenidate<span> after a failed treatment with venlafaxine<span> and risperidone.</span></span></p></div><div><h3>Results</h3><p><span><span><span>We review the role of dopamine in the pathophysiology of PTSD and the scarce studies in the treatment of PTSD with </span>dopaminergic </span>drugs<span> that show an improvement in re-experimentation and in affective symptoms, especially anhedonia and </span></span>cognitive impairment.</p></div><div><h3>Conclusions</h3><p>We conclude that the use of methylphenidate and other dopaminergic drugs can be a promising treatment for PTSD, a high prevalent disease with a high resistance to treatment, for which we encourage the use of large sample studies.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49841733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chatbots and psychiatry: Beware of hallucinations of artificial intelligence 聊天机器人和精神病学:当心人工智能的幻觉

Psiquiatria Biologica Pub Date : 2023-01-01 DOI: 10.1016/j.psiq.2023.100394

Jesús Enrique Ibáñez Vizoso , Agustín Bermejo Pastor

引用次数: 0

Olanzapina, 26 años: situación actual, conocimientos, actitudes y prácticas de uso entre los psiquiatras españoles 奥氮平，26岁:西班牙精神科医生的现状、知识、态度和使用做法

Psiquiatria Biologica Pub Date : 2023-01-01 DOI: 10.1016/j.psiq.2022.100391

Jairo M. Gonzalez-Diaz , Miquel Bernardo

{"title":"Olanzapina, 26 años: situación actual, conocimientos, actitudes y prácticas de uso entre los psiquiatras españoles","authors":"Jairo M. Gonzalez-Diaz , Miquel Bernardo","doi":"10.1016/j.psiq.2022.100391","DOIUrl":"https://doi.org/10.1016/j.psiq.2022.100391","url":null,"abstract":"<div><p>Olanzapine, a second-generation antipsychotic marketed in Europe since late 1996, continues to be one of the most widely used molecules in Spain today. However, its high rate of adverse metabolic events and its use in some clinical settings are still controversial. The objective of this study was to explore the knowledge, attitudes, and practices of use of this medication among Spanish psychiatrists. A self-filled questionnaire was designed and distributed. Dosage, experience, and trends of use in different contexts were explored, as well as future expectations. Data were tabulated and a descriptive analysis was performed. 129 practicing psychiatrists throughout the Spanish territory participated in the study, with an average age of 45.46 years (SD=9.57) and a female: male ratio of 1.04:1. After more than 25 years on the market, Olanzapine continues to be an antipsychotic widely used in different clinical settings, both in Schizophrenia and other mental disorders (preferably at doses between 5 and 10 mg/day). Spanish psychiatrists are familiar with the need to establish pharmacological and non-pharmacological strategies for the metabolic control of patients using this drug.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49868833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relación entre la cantidad y el tipo de alcohol (destilado versus fermentado) consumido y el riesgo de aparición de deterioro cognitivo compatible con un síndrome demencial en personas mayores de 60 años: revisión sistemática 酒精消费的数量和类型(蒸馏酒与发酵酒)与60岁以上人群出现与痴呆综合征一致的认知障碍风险之间的关系:系统综述

Psiquiatria Biologica Pub Date : 2023-01-01 DOI: 10.1016/j.psiq.2023.100395

Josep Deví-Bastida , Helena Puig-Martel , Santiago Llana-Cortés , Alexandra García-Guix , M. Teresa Abellán-Vidal , M. Dolores López-Villegas

{"title":"Relación entre la cantidad y el tipo de alcohol (destilado versus fermentado) consumido y el riesgo de aparición de deterioro cognitivo compatible con un síndrome demencial en personas mayores de 60 años: revisión sistemática","authors":"Josep Deví-Bastida , Helena Puig-Martel , Santiago Llana-Cortés , Alexandra García-Guix , M. Teresa Abellán-Vidal , M. Dolores López-Villegas","doi":"10.1016/j.psiq.2023.100395","DOIUrl":"https://doi.org/10.1016/j.psiq.2023.100395","url":null,"abstract":"<div><h3>Introduction</h3><p>Alcohol is the most consumed substance in Western culture and its consumption is a causal factor in more than 200 diseases and disorders. The objective was to determine the relationship between the amount and type of alcohol (distilled or fermented) consumed, in individuals over 60 years of age, and the appearance of cognitive deterioration compatible with a dementia syndrome as a consequence of excessive and prolonged consumption.</p></div><div><h3>Development</h3><p>Search in Medline, PsycInfo and Web of Science databases. The search was limited to articles published between 2010 and 2021, based on the combination of various terms related to dementia, alcohol consumption and type, and old age. 157 articles were obtained, those repeated and those not related to the topic were eliminated, leaving a total of 9 articles. This systematic review has been carried out in accordance with the criteria of the PRISMA statement.</p></div><div><h3>Conclusions</h3><p>Most of the studies found (7 out of 9) suggested an association between alcohol consumption and the onset of dementia. Regarding the type of beverages, everything and the objectification of some inconclusive results, in general it is suggested that the consumption of wine (fermented beverage) is associated with a decrease of cognitive deterioration and the consumption of liquor (distilled beverage) to a increased cognitive decline; the role of beer is not clear. Therefore, it can be concluded that the association between alcohol consumption and greater or lesser cognitive impairment depends both on excessive and prolonged consumption, as well as on the type of beverages consumed (distilled or fermented).</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49868832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Utilidad diagnóstica de la secuenciación de segunda y tercera generación en pacientes con discapacidad intelectual: revisión rápida 第二代和第三代测序对智障患者的诊断价值：快速回顾

Psiquiatria Biologica Pub Date : 2023-01-01 DOI: 10.1016/j.psiq.2023.100392

Hugo H. Abarca-Barriga , Flor Vásquez-Sotomayor

{"title":"Utilidad diagnóstica de la secuenciación de segunda y tercera generación en pacientes con discapacidad intelectual: revisión rápida","authors":"Hugo H. Abarca-Barriga , Flor Vásquez-Sotomayor","doi":"10.1016/j.psiq.2023.100392","DOIUrl":"https://doi.org/10.1016/j.psiq.2023.100392","url":null,"abstract":"<div><h3>Introduction</h3><p>Some populations have an intellectual disability frequency of nearly 18%. Among, the diverse genetic causes are single nucleotide variants and copy number variations, detected with second-generation sequencing and chromosomal microarray analysis, respectively. Nevertheless, other variants such as structural variants, trinucleotide repeat or imprinting disorders, cannot be detected by these tests and require different specific techniques. Third-generation sequencing have a power of found all variants. The purpose is to stablish the benefits of using third generation sequencing above second-generation sequencing in the diagnosis of patient with intellectual disability.</p></div><div><h3>Material and methods</h3><p>A rapid systematic review was performed on the Medline using thesaurus terms MESH of “intellectual disability” and “second-generation sequencing”; as well as using the term “third-generation sequencing”.</p></div><div><h3>Results</h3><p>31 articles were selected in total. Of those, nine used third-generation sequencing in patients with previously genomic test, and founded structural variants in 40% of cases, all these variants were corroborated with other gold standard tests. Twenty-two studies used second-generation sequencing (n = 22) and showed through metanalysis, that 29,8% and 9,2% of these cases are due a single nucleotide variant and copy number variations, respectively.</p></div><div><h3>Conclusions</h3><p>Third-generation sequencing can find structural variants, uniparental disomies, trinucleotide repeat and single nucleotide variation. Therefore, it would allow a broader and better study of the etiology of intellectual disability. Nevertheless, more research with larger representative samples in patients and healthy population is needed.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49830961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Are there still endogenous and reactive depressions? Clinical notes from a refractory Cotard Syndrome with a de novo post-ECT dissociative episode 是否还有内源性和反应性抑郁?难治性科塔尔综合征伴电痉挛后解离发作的临床记录

Psiquiatria Biologica Pub Date : 2022-09-01 DOI: 10.1016/j.psiq.2022.100379

Alexandre P. Gomes , Liliana C. Gomes , Eduardo Gonçalves , Emanuel L. Santos

{"title":"Are there still endogenous and reactive depressions? Clinical notes from a refractory Cotard Syndrome with a de novo post-ECT dissociative episode","authors":"Alexandre P. Gomes , Liliana C. Gomes , Eduardo Gonçalves , Emanuel L. Santos","doi":"10.1016/j.psiq.2022.100379","DOIUrl":"10.1016/j.psiq.2022.100379","url":null,"abstract":"<div><p><span><span>Cotard syndrome is a mysterious and severe disorder. Many therapeutic interventions are reported as potentially efficacious mostly when an underlying psychotic depression<span> or melancholia is diagnosed. However, the classification of depression has long been a contentious issue. Even though the major guide for therapeutic choice is severity, the binary model between endogenous and reactive depression is still widely employed in clinical practice. These considerations impact most clearly in in-between presentations. The authors present the case of R., a 64 year old woman, who was admitted with a major depressive episode with psychotic features, captured as a Cotard-like syndrome. After a two-months inpatient period and apparent clinical remission with high dose antidepressants and </span></span>antipsychotic combination, she displayed an acute worsening leading to a re-admission just a day </span>after discharge<span>. The management in this second admission was tortuous, due to SARS-CoV2 related contingencies, the refractoriness of the presentation and iatrogenic intercurrences. The authors expose the course and treatment options employed, while reflecting on the question endogenous v. reactive, concluding that even seemingly clear clinical presentations may resist our different conceptualizations.</span></p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126676411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1