抗药性重度抑郁症。电休克疗法与斯氯胺酮：应该选择哪一种？病例报告

Q4 Medicine

Psiquiatria Biologica Pub Date : 2024-07-01 DOI:10.1016/j.psiq.2024.100488

Belén Urbán Antón, Miguel Omaña Colmenares, Juan Fuertes Aparicio

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引用次数: 0

摘要

我们介绍了一例对多种抗抑郁药和电休克疗法均有耐药性的 73 岁女性抑郁症患者的病例，经过 4 个月的治疗，她的 MADRS 评分从 43 分（重度抑郁）降至 18 分（轻度抑郁），并在鼻内注射艾司氯胺酮后病情明显好转。这些结果提出了一个问题：对于患有抗药性抑郁症并有自杀倾向的老年患者，我们是否应该选择电休克疗法或鼻内注射艾司氯胺酮？

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Depresión mayor resistente. Terapia electroconvulsiva versus esketamina. ¿Cuál debería ser el orden? A propósito de un caso

We present a case of a 73-year-old woman with a treatment- resistant depression to several antidepressants and electroconvulsive therapy, who improved significantly with intranasal esketamine showing a decrease in the MADRS score from 43 points (severe depression) to 18 points (mild depression) after 4 months of treatment. These results raise the question of whether, in elderly patients suffering a treatment- resistant depression and suicidal ideation, we should choose either electroconvulsive therapy or intranasal esketamine.

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来源期刊

Psiquiatria Biologica Medicine-Psychiatry and Mental Health

CiteScore

0.40

自引率

0.00%

发文量

期刊介绍： Es la Publicación Oficial de la Sociedad Española de Psiquiatría Biológica. Los recientes avances en el conocimiento de la bioquímica y de la fisiología cerebrales y el progreso en general en el campo de las neurociencias han abierto el camino al desarrollo de la psiquiatría biológica, fundada sobre bases anatomofisiológicas, más sólidas y científicas que la psiquiatría tradicional.