Psiquiatria Biologica最新文献_第4页

Conducta suicida en interconsulta: Comparación entre pacientes mayores y menores de 65 años 咨询期间的自杀行为：老年人与65岁以下患者的比较

Psiquiatria Biologica Pub Date : 2024-12-01 DOI: 10.1016/j.psiq.2024.100552

Jesús Ángel Monforte Porto, Alberto de Vega Martín, Marisol Asperilla Gallardo

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Consumo de sustancias ilícitas y suicidio consumado desde una perspectiva de género 从性别角度看非法药物使用和自杀

Psiquiatria Biologica Pub Date : 2024-12-01 DOI: 10.1016/j.psiq.2024.100555

Miguel Zacarías Pérez Sosa, Diego de la Vega Sánchez

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Decoding a case of pica: The path to a difficult diagnosis 解读异食癖病例：通往艰难诊断的道路

Psiquiatria Biologica Pub Date : 2024-11-30 DOI: 10.1016/j.psiq.2024.100550

Ignacio Ramos Suárez , Margarita Guerrero Jiménez

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Huntington latente desenmascarado por aripiprazol 阿立哌唑暴露的亨廷顿潜伏期

Psiquiatria Biologica Pub Date : 2024-11-26 DOI: 10.1016/j.psiq.2024.100549

Elena Blanco-Martin, Maria Nieto-Compán, Jorge López-Álvarez

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The MCOSUL cohort: Lethality, recurrence, and mortality in suicide attempts in the Lérida Region, Spain—Rationale, objectives, and preliminary findings mccosul队列研究：西班牙lsamrida地区自杀企图的致死率、复发率和死亡率——基本原理、目的和初步调查结果

Psiquiatria Biologica Pub Date : 2024-11-26 DOI: 10.1016/j.psiq.2024.100548

María Irigoyen-Otiñano , Vicent Llorca-Bofí , Marina Adrados-Pérez , Laura Arenas-Pijoan , Eugènia Nicolau-Subires , Carla Albert-Porcar , Lucía Ibarra-Pertusa , Margarita Puigdevall-Ruestes

{"title":"The MCOSUL cohort: Lethality, recurrence, and mortality in suicide attempts in the Lérida Region, Spain—Rationale, objectives, and preliminary findings","authors":"María Irigoyen-Otiñano , Vicent Llorca-Bofí , Marina Adrados-Pérez , Laura Arenas-Pijoan , Eugènia Nicolau-Subires , Carla Albert-Porcar , Lucía Ibarra-Pertusa , Margarita Puigdevall-Ruestes","doi":"10.1016/j.psiq.2024.100548","DOIUrl":"10.1016/j.psiq.2024.100548","url":null,"abstract":"<div><h3>Background and objectives</h3><div>Suicide is a major global health issue with profound impacts on individuals, families, and societies. Understanding the factors that influence the lethality of suicide attempts, the frequency of reattempts, ultimate causes of death, and associated immune biomarkers is crucial for developing effective prevention strategies. This article outlines the rationale, objectives, and protocol of a new cohort study, presenting preliminary descriptive results.</div></div><div><h3>Methods</h3><div>We designed a prospective, naturalistic cohort study involving patients from the Arnau de Vilanova and Santa Maria University Hospitals in Lleida, Spain. Participants are recruited following a suicide attempt and are monitored over time. Data on clinical assessments, suicidal methods, somatic lethality, immune biomarkers, reattempts, and causes of death are collected and analyzed. The cohort continues to recruit patients and update follow-up data.</div></div><div><h3>Results</h3><div>Currently, the cohort includes 1918 patients. The majority of participants are females (62.8%) with an average age of 41.2 years. The average follow-up period is 77.6 months. Sedative poisoning is the most common method of suicide attempt (57.3%). High lethality attempts predominate (76.7%), and 43.4% of patients have reattempted suicide. During follow-up, 5.5% of patients died, with 2.1% of deaths attributed to suicide.</div></div><div><h3>Conclusion</h3><div>The findings from this study are expected to enhance our understanding of the relationships between suicide lethality, reattempts, mortality, and immune biomarkers. This knowledge may help to personalize interventions aimed at reducing suicide rates and improving outcomes for individuals at high risk.</div></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"32 2","pages":"Article 100548"},"PeriodicalIF":0.0,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143136901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of stimulant medications on immunity in the treatment of attention deficit hyperactivity disorder 兴奋剂治疗注意缺陷多动障碍对免疫的影响

Psiquiatria Biologica Pub Date : 2024-11-23 DOI: 10.1016/j.psiq.2024.100546

Alberto Rodríguez-Quiroga , Miriam Akasbi Montalvo , Miguel Ángel Álvarez-Mon González , Fernando Mora Mínguez , Javier Quintero Gutiérrez del Álamo

{"title":"Effect of stimulant medications on immunity in the treatment of attention deficit hyperactivity disorder","authors":"Alberto Rodríguez-Quiroga , Miriam Akasbi Montalvo , Miguel Ángel Álvarez-Mon González , Fernando Mora Mínguez , Javier Quintero Gutiérrez del Álamo","doi":"10.1016/j.psiq.2024.100546","DOIUrl":"10.1016/j.psiq.2024.100546","url":null,"abstract":"<div><h3>Background</h3><div>Research suggests a potential link between attention deficit hyperactivity disorder (ADHD) and the immune system, with higher rates of allergic conditions observed in ADHD patients. Altered levels of cytokines, crucial immune signaling molecules, are also associated with ADHD, and stimulant medications may modulate immune activity.</div></div><div><h3>Objective</h3><div>The objective is to raise awareness of the intricate relationship between ADHD and the immune system, shedding light on its potential implications for treatment and management strategies.</div></div><div><h3>Material and methods</h3><div>Descriptive study of the case report type based on the case report guidelines.</div></div><div><h3>Case description</h3><div>A 41-year-old male with systemic lupus erythematosus (SLE) was referred for anxiety symptoms. His medical history included SLE diagnosis and chronic steroid therapy. He reported inconsistent attention, difficulty in task planning and organization, restlessness, and impulsivity. Comprehensive assessment confirmed ADHD diagnosis. He was prescribed melatonin, vortioxetine, and methylphenidate, which significantly improved his symptoms. SLE antibody levels decreased with treatment.</div></div><div><h3>Conclusion</h3><div>The detection of ADHD and specific treatment with stimulants not only improved his symptoms but also led to a decrease in SLE antibodies and an enhancement in quality of life for the patient.</div></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"32 2","pages":"Article 100546"},"PeriodicalIF":0.0,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143136936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

First experiences with esketamine nasal spray in patients with moderate and severe treatment-resistant depression 艾氯胺酮鼻腔喷雾剂治疗中度和重度难治性抑郁症的首次经验

Psiquiatria Biologica Pub Date : 2024-11-23 DOI: 10.1016/j.psiq.2024.100547

José Miguel Meca García, María Teresa Perní Lasala, María Beret Trancón, Ricardo Jesús Lara Mellado, Antonio José Ureña Caballero, Raquel Fernández Villalobos, José Enrique Romero Baca

引用次数: 0

Tamizaje del trastorno por déficit de atención e hiperactividad (TDAH) en pacientes hospitalizados por farmacodependencia en una unidad de salud mental en Barranquilla, Colombia 在哥伦比亚巴兰基利亚的一个精神卫生单位，对因药物依赖而住院的患者进行注意缺陷/多动障碍（ADHD）筛查

Psiquiatria Biologica Pub Date : 2024-11-21 DOI: 10.1016/j.psiq.2024.100544

Natalia Gutierrez-Marchena , Anderson David Padilla-Menco , Dania Lucía Ruiz-Plaza

{"title":"Tamizaje del trastorno por déficit de atención e hiperactividad (TDAH) en pacientes hospitalizados por farmacodependencia en una unidad de salud mental en Barranquilla, Colombia","authors":"Natalia Gutierrez-Marchena , Anderson David Padilla-Menco , Dania Lucía Ruiz-Plaza","doi":"10.1016/j.psiq.2024.100544","DOIUrl":"10.1016/j.psiq.2024.100544","url":null,"abstract":"<div><div>Attention Deficit Hyperactivity Disorder (ADHD) is considered a neurodevelopmental disorder that typically presents in childhood and can continue into adulthood. Mainly affects three areas given by attention, impulse control, and hyperactivity, which end up affecting the psychosocial development, interpersonal relationships, and academic level of the subject. The prevalence varies depending on age group, sex, and location; however, it is estimated at 7% overall in the pediatric population and 4.5% in adults. ADHD symptoms have been found to predict tobacco, alcohol, and cannabis use; and additionally, if left untreated, it is estimated that up to 50% of people with ADHD will manifest a substance use disorder at some point in their lives, however there are no data on such comorbidity in our population, so we consider necessary to determine the prevalence of ADHD in the population hospitalized for Substance Use Disorder (SUD) in the mental health institution through screening with self-report scales. Here we report the sociodemographic characterization, drug use pattern and comorbidities of this population, as well as the result of screening with the Wender Utah Scale (WURS-25) and Adult ADHD Self Report Scale (ASRS V1.1). The study included a total of 74 subjects who were hospitalized in a mental health institution located in Barranquilla, Colombia, with a diagnosis of SUD. It was found that 50% of patients scored positive for ADHD diagnosis according to the ASRS scale, probable diagnosis 20.3% and unlikely 29.7%, with 44.6% positive on the WURS-25 scale. The results of the present study suggest that screening for ADHD is a useful tool to detect comorbidity in patients with SUD, who could benefit from comprehensive treatment for both pathologies and thus impact the course and prognosis of the disease, as well as their functionality and quality of life.</div></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"32 2","pages":"Article 100544"},"PeriodicalIF":0.0,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143136902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnóstico diferencial del mutismo selectivo a través de un caso clínico 通过临床病例对选择性沉默进行鉴别诊断

Psiquiatria Biologica Pub Date : 2024-11-19 DOI: 10.1016/j.psiq.2024.100543

Sandra Puyal González , Carlos-Luis Ortiz Sánchez-Expósito , Almudena Escudero González

引用次数: 0

Encefalitis autoinmune por anticuerpos antirreceptor de NMDA: a propósito de un caso NMDA受体抗体引起的自身免疫性脑炎：以一个病例为例

Psiquiatria Biologica Pub Date : 2024-11-16 DOI: 10.1016/j.psiq.2024.100541

Vanessa Gladys Velasquez Acebey, Maite Sellart Altisent

{"title":"Encefalitis autoinmune por anticuerpos antirreceptor de NMDA: a propósito de un caso","authors":"Vanessa Gladys Velasquez Acebey, Maite Sellart Altisent","doi":"10.1016/j.psiq.2024.100541","DOIUrl":"10.1016/j.psiq.2024.100541","url":null,"abstract":"<div><h3>Introduction</h3><div>Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is the most common form of autoimmune encephalitis. It usually begins with psychiatric symptoms and heterogeneous manifestations that make diagnosis challenging, thereby delaying appropriate treatment. It is crucial to be aware of this condition and to consider it for exclusion in cases of atypical first psychotic episodes.</div></div><div><h3>Clinical findings and diagnosis</h3><div>We present the case of a 28-year-old woman who visited the emergency room five times over 12 days due to generalized tonic–clonic seizures, accompanied by psychotic symptoms. She was initially diagnosed with a conversion disorder at two general hospitals before being referred for urgent psychiatric admission. A neurology consultation revealed positive anti-NMDA antibodies (1:16) in cerebrospinal fluid (CSF), leading to the diagnosis of anti-NMDAR encephalitis. A gynecology consultation subsequently detected a left ovarian teratoma.</div></div><div><h3>Conclusions</h3><div>In the event of a first psychotic episode with additional neurological symptoms or poor evolution, encephalitis should be excluded. In some cases, magnetic resonance imaging (MRI) and electroencephalographic (EEG) patterns may be normal, making CSF analysis essential. Given the strong association of tumors with anti-NMDAR encephalitis, particularly ovarian teratomas in young women, good coordination between services is critical for early diagnosis and treatment.</div></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":"32 2","pages":"Article 100541"},"PeriodicalIF":0.0,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143136935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0