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Catatonia induced by abrupt discontinuation of clozapine—case report 突然停用氯氮平引发的紧张症--病例报告
Psiquiatria Biologica Pub Date : 2024-05-11 DOI: 10.1016/j.psiq.2024.100482
Catarina M. Oliveira, Liliana Gomes, Paulo S. Martins, Catarina Portela, Filipa Caldas, Marta Gonçalves
{"title":"Catatonia induced by abrupt discontinuation of clozapine—case report","authors":"Catarina M. Oliveira,&nbsp;Liliana Gomes,&nbsp;Paulo S. Martins,&nbsp;Catarina Portela,&nbsp;Filipa Caldas,&nbsp;Marta Gonçalves","doi":"10.1016/j.psiq.2024.100482","DOIUrl":"10.1016/j.psiq.2024.100482","url":null,"abstract":"<div><p>Catatonia is characterized by a severe psychomotor change that, according to DSM-5, requires 3 or more of the following symptoms that is necessary to affirm its diagnosis: stupor, catalepsy, brain flexibility, mutism, negativism, posturing, mannerisms, stereotypes, agitation not influenced by external stimuli, grimaces, echolalia, or echopraxia. Clozapine is one of the second-generation antipsychotics that is recognized for its effectiveness in treating catatonia, rather than inducing it. However, its abrupt discontinuation can induce rapid clinical deterioration with multiple presentations including, psychoses or cholinergic rebound states, serotonergic syndromes, and catatonia.</p><p>Based on a clinical case, the authors intend to review the literature on catatonia associated with abrupt interruption of clozapine.</p><p>In this article, we present a case of a 34-year-old man, with a diagnosis of schizoaffective disorder, admitted to the psychiatric ward due to a psychotic decompensation, who developed a state of agitated catatonia secondary to the abrupt discontinuation of clozapine.</p><p>It is well established that the abrupt discontinuation of clozapine can trigger catatonia. This clinical case and literature review serves to emphasize the importance of educating psychiatrists on the adverse effects of psychiatric drugs and, in this case, the gradual and cautious discontinuation of clozapine in order to avoid its rebound effects.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141039750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
10 years of hyponatremia: Focus on medical communication in liaison psychiatry. A case report 低钠血症 10 年:关注精神病学联络中的医疗沟通。病例报告
Psiquiatria Biologica Pub Date : 2024-04-05 DOI: 10.1016/j.psiq.2024.100472
Catarina Pinho , Emanuela Maldonado , Joana Correia , Manuel Guimarães , André Novo , Joana Raposo Gomes , Conceição Cardoso
{"title":"10 years of hyponatremia: Focus on medical communication in liaison psychiatry. A case report","authors":"Catarina Pinho ,&nbsp;Emanuela Maldonado ,&nbsp;Joana Correia ,&nbsp;Manuel Guimarães ,&nbsp;André Novo ,&nbsp;Joana Raposo Gomes ,&nbsp;Conceição Cardoso","doi":"10.1016/j.psiq.2024.100472","DOIUrl":"https://doi.org/10.1016/j.psiq.2024.100472","url":null,"abstract":"<div><h3>Background</h3><p>Effective communication is one of the pillars of the doctor–patient relationship. Hyponatremia is defined as a decrease in serum sodium levels below 135 mEq/L.</p></div><div><h3>Objective</h3><p>To draw attention to the possible results of ineffective medical communication and the importance of active listening to the patient.</p></div><div><h3>Material and methods</h3><p>Descriptive study of the Case Report type, based on the Case REport guidelines.</p></div><div><h3>Case description</h3><p>An 85-year-old female, hospitalized from October to December 2021 in acute psychiatry for self-injurious behavior following an experiential crisis. In this episode, hyponatremia with 10 years of evolution was detected. She was evaluated by multiple medical specialties and in the last 10 years suffered from anorexia, asthenia, insomnia, and dizziness, a condition attributed to psychoactive drug-related hyponatremia. After hospitalization in psychiatry, it was found that this condition started before the introduction of psychotropic drugs and that there could be a total restriction of salt in the diet, motivated by a bias in doctor–patient communication.</p></div><div><h3>Conclusion</h3><p>With a careful collection of the patient's history, it is possible to deconstruct and clarify concepts and beliefs that can negatively affect her health status.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140645429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
«La piel que habito»: a propósito de un caso de síndrome de Ekbom "我生活的皮肤:一例埃克博姆综合征。
Psiquiatria Biologica Pub Date : 2024-04-01 DOI: 10.1016/j.psiq.2024.100467
Patricia Latorre Forcén , Cristian Blanco Torrecilla , Cristina Antoñanzas Pérez
{"title":"«La piel que habito»: a propósito de un caso de síndrome de Ekbom","authors":"Patricia Latorre Forcén ,&nbsp;Cristian Blanco Torrecilla ,&nbsp;Cristina Antoñanzas Pérez","doi":"10.1016/j.psiq.2024.100467","DOIUrl":"10.1016/j.psiq.2024.100467","url":null,"abstract":"<div><p>The Ekbom's syndrome or delusion of parasitosis is characterized by the firm belief of being infested, generating behavioral impacts such as the fact of presenting injuries from scratching or investing almost all of their time in disinfecting, as in the case that we describe below. Few studies have been published on this delusion, generally from specific patients. The typical presentation of the case is a middle-aged woman, who goes to the dermatologist or internist's department. The appeareance of anxious-depressive symptoms, consistent with the delusional belief, are frequent. It is known that the prognosis improves considerably when the symptomatic period prior to treatment is very short. Therefore, in order to make a good diagnosis and therapeutic management, it is important to establish close collaboration between the different health professionals.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140269921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Un caso de parafrenia. Atención por parte de un equipo de psiquiatría de enlace 一例副恐惧症。由精神病学联络小组提供护理。
Psiquiatria Biologica Pub Date : 2024-04-01 DOI: 10.1016/j.psiq.2024.100474
Beatriz Fernández Durán, Sara Santamaría Rodríguez, Eduardo Delgado Parada
{"title":"Un caso de parafrenia. Atención por parte de un equipo de psiquiatría de enlace","authors":"Beatriz Fernández Durán,&nbsp;Sara Santamaría Rodríguez,&nbsp;Eduardo Delgado Parada","doi":"10.1016/j.psiq.2024.100474","DOIUrl":"10.1016/j.psiq.2024.100474","url":null,"abstract":"<div><p><em>Objective:</em> In reference to a case of hallucinatory psychosis in an elderly individual treated by the Liaison Psychiatry Team, we will conduct a historical review of the term paraphrenia, linking it to the characteristics of this condition, its treatment, and progression.</p><p><em>Clinical Case:</em> A nonagenarian woman admitted to the Internal Medicine service due to behavioral disturbances of several months' duration. She presents delusional ideas of persecution and visual and auditory hallucinations. There is no history of mental health issues or cognitive impairment. Relevant comorbidities include lumbar canal stenosis and moderate hearing loss.</p><p><em>Results:</em> Additional tests ruled out brain damage, toxic psychosis, neurodegenerative disorders, and delirium. With the approach and follow-up conducted (including antipsychotic treatment), the patient showed sustained behavioral improvement and partial encapsulation of the delusion.</p><p><em>Conclusions:</em> Although paraphrenia is not recognized as a distinct entity in current diagnostic classifications, there are cases that warrant consideration; patients with a well-systematized delusion, onset in late age, and bizarre perceptual phenomena of a unique pathoplasty.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140399735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Paternal postpartum depression: A reflection through a case report 父亲产后抑郁症:通过病例报告进行反思。
Psiquiatria Biologica Pub Date : 2024-04-01 DOI: 10.1016/j.psiq.2024.100469
Beatriz Fonseca Silva, Odete Nombora, Ângela Venâncio, André Oliveira
{"title":"Paternal postpartum depression: A reflection through a case report","authors":"Beatriz Fonseca Silva,&nbsp;Odete Nombora,&nbsp;Ângela Venâncio,&nbsp;André Oliveira","doi":"10.1016/j.psiq.2024.100469","DOIUrl":"10.1016/j.psiq.2024.100469","url":null,"abstract":"<div><p>Fathers may also develop depressive symptoms in perinatal period, a condition known as paternal postpartum depression (PPD). Through an intriguing case report, we intend to reflect on PPD, emphasizing the symptomatology, risk factors, and early interventions.</p><p>We present a clinical case of a 42-year-old man observed in a psychiatry emergency in the context of a suicide attempt. He reported progressive depressive symptoms since the last trimester of his wife's last pregnancy. He could not recognize any precipitating factors besides the fear of not being a good father and husband. He also refused hospitalization but accepted treatment and follow-up.</p><p>This case highlights the need to focus on fathers' emotional well-being in the perinatal period, conduct further research on PPD and the creation of appropriate diagnostic tools to assess the symptomatology of depression in males. Screening programs and tools for maternal perinatal depression, follow-up, and intervention as necessary may be valuables strategies.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140273695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of frontotemporal dementia in a patient followed up with late-onset bipolar disorder: A case report 一名晚发躁郁症患者的额颞叶痴呆发展:病例报告。
Psiquiatria Biologica Pub Date : 2024-04-01 DOI: 10.1016/j.psiq.2024.100473
Merve Şahin Can, Sinan Altunöz, Hediye Hilal Yapıcı, Hayriye Baykan
{"title":"Development of frontotemporal dementia in a patient followed up with late-onset bipolar disorder: A case report","authors":"Merve Şahin Can,&nbsp;Sinan Altunöz,&nbsp;Hediye Hilal Yapıcı,&nbsp;Hayriye Baykan","doi":"10.1016/j.psiq.2024.100473","DOIUrl":"10.1016/j.psiq.2024.100473","url":null,"abstract":"<div><p>Frontotemporal dementia is an insidious neurodegenerative clinical syndrome characterized by progressive deficits in behavior, executive function, and language. The initial clinical presentation of some patients with FTD may resemble bipolar mood disorder.In this case, it was planned to diagnose FTD in addition to the emergence of behavioral and cognitive problems in the patient followed up with bipolar mood disorder and to discuss the difficulties experienced in the treatment. In 2017, he was diagnosed with bipolar mood disorder due to loud speech, irritability, thinking that he was cast under a spell, increased spending, driving fast, swearing at relatives. He was followed up with lithium, olanzapine and quetiapine treatment, and he benefited from the treatment. The diagnosis of frontotemporal dementia was considered in the patient who underwent brain diffusion MRI and PET CT in December 2020, upon the onset of the complaint of forgetfulness. Informed consent was obtained from the patient and his relatives.In conclusion, in our case who was followed up with bipolar disorder, a co-diagnosis of frontotemporal dementia was made with the emergence of memory and behavioral pathologies in the later follow-ups. With the diagnosis of FTD, the severity of the patient's manic episodes, clinical presentation, and treatment response changed. Therefore, FTD should be considered in the differential diagnosis of patients who are followed up with bipolar disorder and subsequently have clinical changes.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140781522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
No adherencia en pacientes con esquizofrenia y trastorno esquizoafectivo. Estudio prospectivo de variables asociadas y posibles subtipos "精神分裂症和情感分裂症患者不坚持服药。相关变量和可能亚型的前瞻性研究"。
Psiquiatria Biologica Pub Date : 2024-04-01 DOI: 10.1016/j.psiq.2024.100466
Dulcinea Vega , Francisco J. Acosta , Pedro Saavedra , Guillermo Pírez
{"title":"No adherencia en pacientes con esquizofrenia y trastorno esquizoafectivo. Estudio prospectivo de variables asociadas y posibles subtipos","authors":"Dulcinea Vega ,&nbsp;Francisco J. Acosta ,&nbsp;Pedro Saavedra ,&nbsp;Guillermo Pírez","doi":"10.1016/j.psiq.2024.100466","DOIUrl":"10.1016/j.psiq.2024.100466","url":null,"abstract":"<div><h3>Introduction</h3><p>The rate of non-adherence to treatment in schizophrenia is between 40 and 50%. The scarcity of consistently identified variables associated with nonadherence could be due to real heterogeneity among nonadherent patients.</p></div><div><h3>Objectives</h3><p>Evaluate the prevalence of non-adherence in patients with schizophrenia or schizoaffective disorder. Evaluate the possible subtypes of non-adherence according to intentionality.</p></div><div><h3>Methodology</h3><p>110 consecutively admitted patients diagnosed with schizophrenia and schizoaffective disorder were included. They were evaluated during admission and six months after hospital discharge. Sociodemographic, clinical, psychopathological, and treatment-related variables were included. Adherence was defined as the concurrence of adherence to antipsychotic treatment and follow-up. The subtype of non-adherence was established according to the main reason for non-adherence.</p></div><div><h3>Results</h3><p>Non-adherence was found in 58.2% of the patients. Low socioeconomic status, cannabis use, nonadherence as a reason for relapse and admission, and severity of symptoms were independently associated with nonadherence. Low educational level, poorer treatment knowledge at six months, and use of non-psychiatric treatment at six months were independently associated with the subtype of unintentional non-adherence.</p></div><div><h3>Conclusions</h3><p>A high percentage of patients with schizophrenia and schizoaffective disorder do not show adherence after hospital discharge. There seem to be subtypes of non-adherence according to the intention, which suggests the need for a differentiated approach.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140273977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Levels of depression and quality of life in patients hospitalized for moderate–severe COVID-19 in a regional hospital: INTER-MONF study 一家地区医院中度-重度 COVID-19 住院患者的抑郁程度和生活质量:INTER-MONF 研究。
Psiquiatria Biologica Pub Date : 2024-04-01 DOI: 10.1016/j.psiq.2024.100468
Romina González Vázquez , Manuel Lorenzo López Reboiro , Peter F. Armanious , Estefany Díaz de Argueta , Keivan Kianifar Aguilar , María Teresa Alves Pérez , José López Castro
{"title":"Levels of depression and quality of life in patients hospitalized for moderate–severe COVID-19 in a regional hospital: INTER-MONF study","authors":"Romina González Vázquez ,&nbsp;Manuel Lorenzo López Reboiro ,&nbsp;Peter F. Armanious ,&nbsp;Estefany Díaz de Argueta ,&nbsp;Keivan Kianifar Aguilar ,&nbsp;María Teresa Alves Pérez ,&nbsp;José López Castro","doi":"10.1016/j.psiq.2024.100468","DOIUrl":"10.1016/j.psiq.2024.100468","url":null,"abstract":"<div><h3>Background and objectives</h3><p>Coronavirus disease (COVID-19) is an infectious disease that causes both physical and mental sequelae. The aim of the present study was to evaluate the quality of life and the level of depression in post-COVID-19 patients using the SF-36 Questionnaire (SF-36) and the Beck depression inventory (BDI) and to compare it with the quality of life of the general population for the same sex and age group.</p></div><div><h3>Methods</h3><p>A cohort, observational, and prospective study was designed with the survivors of the group of 115 patients hospitalized at Hospital Público de Monforte to whom the SF-36 and BDI were performed.</p></div><div><h3>Results</h3><p>60 patients responded to the questionnaires (mean age 65.24 (±<!--> <!-->15.49) years and 40% women). In the SF-36, the summary of the physical and mental component was, respectively, 47.71(±<!--> <!-->8.48) and 47.25(±<!--> <!-->9.39). Women have lower scores than men in half of the components of the SF-36. The probability of depression inferred by SF-36 was 28% and applying BDI results were 81.67% of the sample were not depressed, 8.33% were mild–moderate depressed, 6,67% were moderate–severe depressed, and 3.33% were severely depressed.</p></div><div><h3>Conclusions</h3><p>Patients who have suffered COVID-19 predisposes to a higher frequency of depression as well as to a worse quality of life in terms of both physical and mental health. This should serve to raise awareness of the follow-up of patients with long COVID-19 in order to prevent, as far as possible, a decrease in their quality of life.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140407777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
El deterioro cognitivo como factor de riesgo del delirium postoperatorio en la cirugía cardiaca basado en el Mini Mental State Examination, en personas mayores de 60 años: una revisión sistemática 根据 60 岁以上人群的迷你精神状态检查,认知障碍是心脏手术术后谵妄的风险因素:系统性综述。
Psiquiatria Biologica Pub Date : 2024-04-01 DOI: 10.1016/j.psiq.2024.100463
Rosanna Ujaldon-Martínez , Josep Deví-Bastida
{"title":"El deterioro cognitivo como factor de riesgo del delirium postoperatorio en la cirugía cardiaca basado en el Mini Mental State Examination, en personas mayores de 60 años: una revisión sistemática","authors":"Rosanna Ujaldon-Martínez ,&nbsp;Josep Deví-Bastida","doi":"10.1016/j.psiq.2024.100463","DOIUrl":"10.1016/j.psiq.2024.100463","url":null,"abstract":"<div><h3>Introduction</h3><p>Delirium is a neurocognitive disorder whose prevalence increases with age. Its incidence after cardiac surgery ranges between 11% and 52%. There are a large number of studies on the risk factors that affect the appearance of postoperative delirium in cardiac surgery, although most of them are oriented to physiological factors, often ignoring the possible relevance of neuropsychological aspects, such as cognitive impairment. The objective of this work was to analyze the influence of cognitive impairment as an independent risk factor (predictor) in the appearance of postoperative delirium based on the Mini Mental State Examination (MMSE), after cardiac surgery.</p></div><div><h3>Development</h3><p>A search was carried out in the databases PubMed, PsycInfo, Scopus and Web of Science. The search was limited to articles published between 2001 and 2022. 384 articles were obtained. Those that were repeated and not related to the topic were eliminated, leaving a total of 8 articles that met the selection criteria. This systematic review was carried out in accordance with the criteria of the PRISMA 2020 statement.</p></div><div><h3>Conclusions</h3><p>A statistically significant correlation was observed between the measure of cognitive impairment, the MMSE, and the different measures of postoperative delirium, in the majority of studies, so it can be concluded that possibly a mild degree of cognitive impairment may be a sufficient condition for the probability of appearance of postoperative delirium in cardiac surgeries in patients over 60 years of age. Therefore, assessment of cognitive impairment using MMSE before cardiac surgery could be useful to predict the development of postoperative delirium in people over 60 years of age.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140270682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long COVID: Clinical features and multidisciplinary approach 长COVID:临床特征和多学科方法
Psiquiatria Biologica Pub Date : 2024-04-01 DOI: 10.1016/j.psiq.2024.100471
A. Serrano García , J. Guerra Laso , L. Linares Álvarez , E. Turrado Valbuena , C. Vilella Martín , P. García Vázquez , C.M. Franch Pato
{"title":"Long COVID: Clinical features and multidisciplinary approach","authors":"A. Serrano García ,&nbsp;J. Guerra Laso ,&nbsp;L. Linares Álvarez ,&nbsp;E. Turrado Valbuena ,&nbsp;C. Vilella Martín ,&nbsp;P. García Vázquez ,&nbsp;C.M. Franch Pato","doi":"10.1016/j.psiq.2024.100471","DOIUrl":"https://doi.org/10.1016/j.psiq.2024.100471","url":null,"abstract":"<div><p>Although most of the patients affected by COVID-19 recover their health and return to their previous situation, some of them present symptoms that can last a long time after the acute illness. The main objective of this study is to assess the correlation between symptoms of long COVID and symptoms of central sensitization. Secondarily, it will try to describe the symptoms of long COVID and its correlation with alexithymia and depression.</p></div><div><h3>Methods</h3><p>Prospective observational study in real clinical conditions. Include consecutively those patients who present long COVID and complete multidisciplinary evaluation by a somatic specialist and a psychiatrist, together with a battery of questionnaires.</p></div><div><h3>Results</h3><p>The profile we found corresponds to a woman, in the middle of her fifth decade of life, with higher education and working, who passed the SARS-CoV-2 infection 1 year earlier, without requiring hospitalization and with a severe depressive disorder and alexithymia. We found an intermediate correlation (rho .665; <em>p</em> &lt; .01) between central sensitization questionnaire and the sum of symptoms of long COVID, as well as between the sum of symptoms presented and depression (rho .467; <em>p</em> &lt; .01) and not between the sum of symptoms and alexithymia (rho .151; <em>p</em> = .359).</p></div><div><h3>Conclusions</h3><p>Sensitization phenomena seem to be of notable importance in the symptoms of long COVID and present a symptomatic constellation characterized by fatigue, difficulty concentrating, and memory problems. Patients with persistent COVID present more severe depressive symptoms than they are capable of perceiving o express.</p></div>","PeriodicalId":39337,"journal":{"name":"Psiquiatria Biologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140649663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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