Suicidio reciente: Inflamación y atención

Q4 Medicine
Jessica Fernández-Sevillano, Itxaso González-Ortega, Iñaki Zorrilla, María Purificación López, Philippe Courtet, Juan Carlos Leza, Ana González-Pinto
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引用次数: 0

Abstract

To test the hypothesis that inflammatory parameters will be elevated in a recent suicide attempt and will be associated with attentional performance, 96 participants were recruited at the Department of Psychiatry of the University Hospital Araba - Santiago, including 20 patients with a recent suicide attempt diagnosed with major depressive disorder, 33 patients with the same diagnosis with past suicide attempts, 23 patients also depressed without suicide attempts and 20 volunteers with no mental health history. The results show that both recent and past suicidal behavior is associated with elevated levels of inflammation. Elevated IL-6 concentration has a reductive impact on attentional performance, increasing the risk of suicide due to incorrect interpretation and response to environmental information.
近期自杀:炎症与关注
为了验证炎症参数会在最近的自杀企图中升高并与注意力表现有关的假设,圣地亚哥大学医院的精神病学部门招募了96名参与者,其中包括20名最近被诊断为重度抑郁症的自杀企图患者,33名被诊断为过去有自杀企图的患者。23名患者也患有抑郁症,但没有自杀企图,20名志愿者没有精神病史。结果表明,最近和过去的自杀行为都与炎症水平升高有关。升高的IL-6浓度对注意力表现有降低的影响,由于对环境信息的错误解释和反应而增加自杀的风险。
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来源期刊
Psiquiatria Biologica
Psiquiatria Biologica Medicine-Psychiatry and Mental Health
CiteScore
0.40
自引率
0.00%
发文量
13
期刊介绍: Es la Publicación Oficial de la Sociedad Española de Psiquiatría Biológica. Los recientes avances en el conocimiento de la bioquímica y de la fisiología cerebrales y el progreso en general en el campo de las neurociencias han abierto el camino al desarrollo de la psiquiatría biológica, fundada sobre bases anatomofisiológicas, más sólidas y científicas que la psiquiatría tradicional.
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