阿立哌唑暴露的亨廷顿潜伏期

Q4 Medicine
Elena Blanco-Martin, Maria Nieto-Compán, Jorge López-Álvarez
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引用次数: 0

摘要

亨廷顿氏病是一种遗传性神经退行性疾病,其症状包括运动障碍、认知障碍和精神症状,通常出现在30至50岁之间。我们提出的情况下,31岁的妇女入院精神病学首次由于抑郁发作与自杀意念。由于运动改变,刻板印象和运动不协调,以前被神经病学评估没有明确的诊断。入院时出现运动症状导致与神经内科会诊。经诊断为锥体外系综合征,怀疑为亨廷顿氏病,后来经基因研究证实。调整用药及停用阿立哌唑后,抑郁及运动症状均有改善。本病例强调了当精神、运动和认知症状同时出现时,考虑神经退行性疾病的重要性。此外,它还展示了药物的副作用如何揭示潜伏的疾病。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Huntington latente desenmascarado por aripiprazol
Huntington's disease is an inherited neurodegenerative disorder whose symptoms include movement disorders, cognitive impairment, and psychiatric symptoms, and usually appear between the ages of 30 and 50. We present the case of a 31-year-old woman admitted to Psychiatry for the first time due to a depressive episode with suicidal ideation. Previously evaluated by Neurology without a clear diagnosis, due to movement alterations, stereotypies and motor incoordination. The presence of motor symptoms during admission led to an interconsultation with the Neurology Department. Extrapyramidal syndrome was diagnosed and Huntington's disease was suspected, later confirmed by genetic studies. After adjusting the medication and eliminating aripiprazole, depressive and motor symptoms improved. This case highlights the importance of considering neurodegenerative diseases when psychiatric, motor, and cognitive symptoms are present simultaneously. In addition, it shows how the side effects of drugs can unmask latent diseases.
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来源期刊
Psiquiatria Biologica
Psiquiatria Biologica Medicine-Psychiatry and Mental Health
CiteScore
0.40
自引率
0.00%
发文量
13
期刊介绍: Es la Publicación Oficial de la Sociedad Española de Psiquiatría Biológica. Los recientes avances en el conocimiento de la bioquímica y de la fisiología cerebrales y el progreso en general en el campo de las neurociencias han abierto el camino al desarrollo de la psiquiatría biológica, fundada sobre bases anatomofisiológicas, más sólidas y científicas que la psiquiatría tradicional.
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