中国血吸虫病防治杂志最新文献

{"title":"[Characterization and phylogenetic evolution of tick - derived Rickettsiales and emerging viruses in northern Jiangsu Province].","authors":"G Chen, W Mei, S Jiang, L Tao, Y Ji, Q Cui, H Zhang, R An, B Xu, W Wang","doi":"10.16250/j.32.1915.2025110","DOIUrl":"https://doi.org/10.16250/j.32.1915.2025110","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the tick species, and tick-derived Rickettsiales bacteria and recently emerging tick-derived viruses in hilly and costal mudflat wetland settings in northern Jiangsu Province, so as to provide insights into management of tick-borne tropical diseases in northern Jiangsu Province.</p><p><strong>Methods: </strong>Ticks were sampled from hilly settings in Yuyi County, Huai'an City and coastal mudflat wetland settings in Jiangsu Yancheng Wetlands & Rare Birds National Nature Reserve in Tinghu District, Yancheng City on April, 2025. Following characterization of tick species, nucleic acid was isolated from ticks under a sterile condition, and tick-derived pathogens were detected using nested and semi-nested real-time PCR assays, including <i>Rickettsia, Ehrlichia</i>, <i>Anaplasma</i>, Yezo virus, Alongshan virus, Songling virus, Beiji nairovirus and Wetland virus. The PCR amplification products were sequenced for analysis of phylogenetic evolution and genetic characteristics.</p><p><strong>Results: </strong>A total of 154 ticks were captured, including 114 from Huai'an City and 40 from Yancheng City, and 153 ticks were characterized as <i>Haemaphysalis longicornis</i> and one as <i>H. flava</i>. A total of 5 ticks were tested positive for Rickettsiales bacteria and viruses by semi-nested real time PCR assay (3.25%), including 4 ticks from hilly settings in Xuyi County, Huai'an City, tested positive for <i>Anaplasma</i>, and one tick from coastal mudflat wetland settings in Tinghu District, Yancheng City, tested positive for <i>Rickettsia</i>; however, ticks were tested negative for <i>Ehrlichia</i>, or recently emerging Yezo virus, Alongshan virus, Songling virus, Beiji nairovirus or Wetland virus. Sequence alignment using BLASTn and phylogenetic analysis revealed that genetic differentiation occurred in four <i>A. bovis</i> isolates in one species of <i>A. bovis</i>, with two genetic clades generated, and one <i>R. japonica</i> variant was identified, with its nucleotide sequences highly homologous to Shandong isolates of <i>R. japonica</i>.</p><p><strong>Conclusions: </strong>Ticks are widely distributed in hilly and costal mudflat wetland settings in northern Jiangsu Province, and tick-derived pathogens have a genetic diversity. Tick-borne <i>Anaplasma</i> and <i>Rickettsia</i> pose a zoonotic potential.</p>","PeriodicalId":38874,"journal":{"name":"中国血吸虫病防治杂志","volume":"37 4","pages":"380-386"},"PeriodicalIF":0.0,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145410371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Metagenomic next - generation sequencing technology and its application in diagnosis of <i>Pneumocystis jirovecii</i> infection: a review].","authors":"T Xue, W Du, Y Zhao, J Xu","doi":"10.16250/j.32.1374.2024277","DOIUrl":"https://doi.org/10.16250/j.32.1374.2024277","url":null,"abstract":"<p><p><i>Pneumocystis jirovecii</i> is an opportunistic fungal pathogen causing fatal <i>Pneumocystis jirovecii</i> pneumonia (PJP) among immunocompromised patients. Conventional pathogen detection Methods have limitations, which hinders early diagnosis and treatment of PJP, resulting in misdiagnosis and underdiagnosis, and high mortality rates. Metagenomic next-generation sequencing (mNGS), which is high in sensitivity and specificity for pathogen detection, enables accurate detection of <i>P. jirovecii</i> and <i>P. jirovecii</i> co-infection with other pathogens, which facilitates timely diagnosis and treatment of PJP. This review summarizes the advances in mNGS technology and its application in diagnosis of PJP, highlighting its critical clinical value in improving diagnostic effectiveness, guiding clinical therapy, and preventing nosocomial transmission of PJP.</p>","PeriodicalId":38874,"journal":{"name":"中国血吸虫病防治杂志","volume":"37 4","pages":"434-446"},"PeriodicalIF":0.0,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145410258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Epidemiological characteristics of severe fever with thrombocytopenia syndrome in China from 2010 to 2023].","authors":"S Du, Y Shi, X Chen, H Liu, L Zhang, X Huang","doi":"10.16250/j.32.1915.2024288","DOIUrl":"https://doi.org/10.16250/j.32.1915.2024288","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To investigate the epidemiological characteristics of severe fever with thrombocytopenia syndrome (SFTS) and to identify factors affecting deaths among SFTS patients in China from 2010 to 2023, so as to provide insights into scientific prevention and control of SFTS.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Demographic and epidemiological characteristics of reported, definitively diagnosed SFTS cases in China from 2010 to 2023 were captured from National Notifiable Infectious Disease Reporting System of China Information System for Disease Control and Prevention, including current residence address, age, gender, occupation, time of incidence and date of death, and the temporal, spatial and population distributions of SFTS cases were analyzed. The county level incidence of reported SFTS cases in China from 2010 to 2023 was subjected to spatial autocorrelation analysis, and the global Moran's &lt;i&gt;I&lt;/i&gt; index was calculated. The high-incidence clusters for SFTS were identified using space-time scan analysis based on a Poisson distribution model, and the relative risk (&lt;i&gt;RR&lt;/i&gt;) and log-likelihood ratio (&lt;i&gt;LLR&lt;/i&gt;) were estimated. In addition, factors affecting the death and their risk levels were identified among SFTS cases using chi-square test and logistic regression models, and the risk of death was evaluated with odds ratio (&lt;i&gt;OR&lt;/i&gt;).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;A total of 27 457 SFTS cases were reported in China from 2010 to 2023, and the number of SFTS cases increased from 71 in 2010 to 5 062 in 2023, appearing a tendency towards a rise (&lt;i&gt;b&lt;/i&gt; = 5.567, &lt;i&gt;t&lt;/i&gt; = 51.35, &lt;i&gt;P&lt;/i&gt; &lt; 0.05). A total of 1 326 deaths occurred during the 14-year study period, with a case fatality rate of 4.82%, and the annual incidence and fatality of SFTS were 0.005/10&lt;sup&gt;5&lt;/sup&gt; to 0.359/10&lt;sup&gt;5&lt;/sup&gt;, and 2.70% to 12.70%. SFTS cases were reported across 27 provinces in China, which were predominantly reported in 7 provinces of Shandong (7 890 cases, 28.74%), Henan (6 286 cases, 22.89%), Anhui (5 718 cases, 20.83%), Hubei (3 938 cases, 14.34%), Liaoning (1 418 cases, 5.16%), Zhejiang (990 cases, 3.61%), and Jiangsu (957 cases, 3.49%), accounting for 99.05% (27 197/27 457) of totally reported cases in China. The time of SFTS incidence appeared a seasonal distribution, and the incidence of SFTS peaked during the period from May to July, with a significant difference in the time of SFTS incidence among provinces (&lt;i&gt;P&lt;/i&gt; &lt; 0.01). Among all SFTS cases, there were 12 894 men (46.96%) and 14 563 women (53.04%), and there were 61.27% (16 823/27 457) of SFTS cases at ages of 61 years and older, with farmers as the predominant occupation (84.74%, 23 266/27 457). The annual Moran's &lt;i&gt;I&lt;/i&gt; index for SFTS incidence ranged from 0.326 2 to 0.607 5 from 2010 to 2023, and there were significant differences in the Moran's &lt;i&gt;I&lt;/i&gt; index for SFTS incidence each year from 2011 to 2023 (&lt;i&gt;Z&lt;/i&gt; = 10.207 to 18.101, all &lt;i&gt;P&lt;/i&gt; values &lt; 0.001), pre","PeriodicalId":38874,"journal":{"name":"中国血吸虫病防治杂志","volume":"37 4","pages":"371-379"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145410343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Visualization analysis of studies on <i>Oncomelania hupensis</i> control from 2005 to 2024].","authors":"W Zhu, H Luo, H Wang, Y Xiong, C Liu","doi":"10.16250/j.32.1915.2025036","DOIUrl":"https://doi.org/10.16250/j.32.1915.2025036","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To analyze Chinese and English publications pertaining to &lt;i&gt;Oncomelania hupensis&lt;/i&gt; control from 2005 to 2024, so as to decipher the research status and hotspots of &lt;i&gt;O. hupensis&lt;/i&gt; control.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Chinese and English publications pertaining to &lt;i&gt;O. hupensis&lt;/i&gt; control from 2005 to 2024 were retrieved in the Web of Science Core Collection Database and China National Knowledge Infrastructure. The annual number of publications was analyzed from 2005 to 2024, and the author and institution cooperation networks were mapped using the software CiteSpace 6.3.1. Keywords were extracted from publications to map the co-occurrence, burst and timeline of keywords to identify the research hotspots of &lt;i&gt;O. hupensis&lt;/i&gt; control.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;A total of 158 English publications and 771 Chinese publications were included for bibliometric analyses. The overall output of English publications was relatively small from 2005 to 2024, the annual average publication was 7.90 publications. &lt;i&gt;Parasites & Vectors&lt;/i&gt; was the most productive journal by the number of publications (21 publications). The three most productive authors included Li Shizhu (24 publications), Zhou Xiaonong (13 publications), and Yang Kun (12 publications), and the three most productive institutions included Chinese Center for Disease Control and Prevention (49 publications), the WHO (27 publications), and Fudan University (25 publications). The annual average number of Chinese publications was high from 2005 to 2015 (57.73 publications), and reduced to 15.11 publications during the period from 2016 to 2024, with &lt;i&gt;Chinese Journal of Schistosomiasis Control&lt;/i&gt; as the most productive journal (241 publications). The three most productive authors included Wang Wanxian (18 publications), Sun Qixiang (16 publications), and Dai Jianrong (16 publications), and the three most productive institutions included Jiangsu Institute of Parasitic Diseases (55 publications), Chinese Center for Disease Control and Prevention (47 publications), and Hubei Uni-versity (38 publications). Among the 158 English publications, molluscicidal effect, climate change, geographic information, biological control, machine learning were current research hotspots, and the Yangtze River and elimination were emerging research hotspots. Among the 771 Chinese publications, molluscicidal effect, niclosamide, comprehensive management, molluscicide, effectiveness evaluation, marshland, and endophyte were current research hotspots, and the future research hotspots shifted to molluscicidal effect and pyriclobenzuron.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;Limited attention is paid to the research on &lt;i&gt;O. hupensis&lt;/i&gt; control across the world. The Yangtze River, elimination, molluscicidal effect, and pyriclobenzuron may be future research hotspots. High attention is recommended to be paid to the research on &lt;i&gt;O. hupensis&lt;/i&gt; control, and development of diverse ","PeriodicalId":38874,"journal":{"name":"中国血吸虫病防治杂志","volume":"38 1","pages":"84-91"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147784202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Cloning and bioinformatics analysis of surface antigen-related sequence protein <i>SRS67</i> and <i>SRS20A</i> genes in <i>Toxoplasma gondii</i>].","authors":"X Chen, D Yin, W Ma, T Yi, H Li, L Liu, Z Liu, M Du, S Zhou, Q Li","doi":"10.16250/j.32.1915.2024275","DOIUrl":"https://doi.org/10.16250/j.32.1915.2024275","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To predict the structures and immunogenicity of surface antigen-related sequence protein SRS67 and SRS20A in &lt;i&gt;Toxoplasma gondii&lt;/i&gt; using bioinformatics methods, and to generate prokaryotic expression vectors for protein expression, so as to identify the functions of recombinant SRS67 and SRS20A proteins and their potential as vaccine candidates against &lt;i&gt;T. gondii&lt;/i&gt;.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;&lt;i&gt;T. gondii SRS67&lt;/i&gt; and &lt;i&gt;SRS20A&lt;/i&gt; gene and amino acid sequences were downloaded from the ToxoDB database. The open reading frames (ORFs) of &lt;i&gt;SRS67&lt;/i&gt; and &lt;i&gt;SRS20A&lt;/i&gt; genes were analyzed in the ORF Finder website. The relative molecular mass, isoelectric point, amino acid composition and lipophilicit index of SRS67 and SRS20A proteins were predicted using the ProtParam software. The protein hydrophilicity/hydrophobicity was predicted using the ProtScale tool, the transmembrane regions were predicted using the TMHMM software, the signal peptides were predicted in the SignalP-4.1 website, the secondary and tertiary structures of the proteins were predicted in the NPS@SPOMA and SWISS-MODEL websites. The phosphorylation sites of the proteins were predicted using the NetPhos-3.1 program, the antigenic epitopes of proteins were predicted using the Immuon medicine Group program. B-cell epitopes, helper T-cell (Th) epitopes, and cytotoxic T lymphocyte (CTL) epitopes were predicted using the IEDB and SYFPEITHI websites, and the antigenicity scores of epitopes were evaluated using the software VaxiJen 2.0 to select the dominant epitopes. Primer sequences were synthesized based on the SRS67 and SRS20A protein-coding gene sequences from the ToxoDB database, and &lt;i&gt;SRS67&lt;/i&gt; and &lt;i&gt;SRS20A&lt;/i&gt; genes were amplified using PCR reactions with &lt;i&gt;T. gondii&lt;/i&gt; cDNA as a template. The amplification products were subjected to double restriction-enzyme digestion, and the target fragments were recovered and ligated into DH5α competent cells with T4 ligase. Positive single colonies were selected and cultured, and the pET-32a-SRS67 and pET-32a-SRS20A recombinant plasmids were extracted, transformed into competent cells for induction of recombinant protein expression. The expression of recombinant proteins was determined using sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and Western blotting.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Bioinformatics analysis predicted that &lt;i&gt;SRS67&lt;/i&gt; and &lt;i&gt;SRS20A&lt;/i&gt; genes were 633 bp and 987 bp in length, contained 7 and 15 ORFs, and encoded 210 and 328 amino acids, respectively. The SRS67 protein had a relative molecular mass of 23 135.65, a signal peptide (&lt;i&gt;D&lt;/i&gt; = 0.590) and no transmembrane regions, contained 22 phosphorylation sites and 8 antigenic determinants, and was a hydrophilic protein. The SRS20A protein had a relative molecular mass of 34 944.91, a signal peptide (&lt;i&gt;D&lt;/i&gt; = 0.697) and transmembrane regions, contained 39 phosphorylation sites and 15 antigenic determ","PeriodicalId":38874,"journal":{"name":"中国血吸虫病防治杂志","volume":"37 4","pages":"387-397"},"PeriodicalIF":0.0,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145410414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Application of eco - immunology in parasitology and parasitic diseases research: a review].","authors":"X Wang, J Yin, H Liu, S Han, Y Hu, Y Shen, J Cao","doi":"10.16250/j.32.1915.2025035","DOIUrl":"https://doi.org/10.16250/j.32.1915.2025035","url":null,"abstract":"<p><p>As an emerging interdisciplinary field bridging ecology and immunology, eco-immunology focuses on the co-evolutionary dynamics between hosts and parasites within natural environments, and aims to unravel the ecological mechanisms underlying the formation of host immune strategies, so as to provide new insights into parasitology and parasitic diseases research. Based on case studies of diverse host-parasite systems, including insects-protozoans, fish-cestodes, amphibians-nematodes, reptiles-arthropods, birds-ectoparasites, and mammals-helminths, this review summarizes critical eco-immunological principles, including host tolerance trade-offs under resource constraints, transgenerational epigenetic adaptation, nutrition-immunity interactions, and immune conflicts triggered by multiparasite co-infections. In addition, the article discusses the feasibility and practical pathways of ecological management and interventions to achieve biodiversity conservation and disease control based on the eco-immunological theory, so as to provide innovative insights into responses to address ecological conservation and public health challenges in the context of global changes.</p>","PeriodicalId":38874,"journal":{"name":"中国血吸虫病防治杂志","volume":"37 4","pages":"428-433"},"PeriodicalIF":0.0,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145410396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Analysis and prediction of global burden due to cystic echinococcosis from 1990 to 2035].","authors":"Z Lai, G Liu, H Zhao, M Qiu, J Chen, E Luo, J Xin, X Yang","doi":"10.16250/j.32.1915.2024195","DOIUrl":"https://doi.org/10.16250/j.32.1915.2024195","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To investigate the trends in the global burden due to cystic echinococcosis from 1990 to 2021, and to predict the global burden of cystic echinococcosis from 2022 to 2035, so as to provide insights into formulation of the cystic echinococcosis control strategy.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;The global age-standardized prevalence, mortality, disability-adjusted life years (DALYs) rates and their 95% uncertainty intervals (&lt;i&gt;UI&lt;/i&gt;) of cystic echinococcosis from 1990 to 2021 were captured from the Global Burden of Disease Study 2021 (GBD 2021) database, and the trends in the global burden of cystic echinococcosis from 1990 to 2021 were analyzed using the Joinpoint regression model. The associations between the global burden of cystic echinococcosis and socio-demographic index (SDI) were examined using a smoothing spline model and frontier analysis, and the global burden of cystic echinococcosis was projected from 2022 to 2035 using the Bayesian age-period-cohort (BAPC) model.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The global agestandardized prevalence, mortality and DALYs rates of cystic echinococcosis were 7.69/10&lt;sup&gt;5&lt;/sup&gt; [95% &lt;i&gt;UI&lt;/i&gt;: (6.27/10&lt;sup&gt;5&lt;/sup&gt;, 9.51/10&lt;sup&gt;5&lt;/sup&gt;)], 0.02/10&lt;sup&gt;5&lt;/sup&gt; [95% &lt;i&gt;UI&lt;/i&gt;: (0.01/10&lt;sup&gt;5&lt;/sup&gt;, 0.02/10&lt;sup&gt;5&lt;/sup&gt;)], and 1.32/10&lt;sup&gt;5&lt;/sup&gt; [95% &lt;i&gt;UI&lt;/i&gt;: (0.99/10&lt;sup&gt;5&lt;/sup&gt;, 1.69/10&lt;sup&gt;5&lt;/sup&gt;)] in 2021. The global age-standardized prevalence of cystic echinococcosis appeared a tendency towards a rise by 0.14% per year from 1990 to 2021, and the global age-standardized mortality and DALYs rates of cystic echinococcosis appeared a tendency towards a decline by 4.68% and 4.01% per year from 1990 to 2021, respectively. Joinpoint regression analysis showed that global age-standardized prevalence of cystic echinococcosis appeared a tendency towards a decline from 1990 to 2000 [annual percent change (APC) = -0.66%, 95% confidence interval (&lt;i&gt;CI&lt;/i&gt;): (-0.70%, -0.61%)] and from 2005 to 2015 [APC = -0.88%, 95% &lt;i&gt;CI&lt;/i&gt;: (-0.93%, -0.82%)], and towards a rise from 2000 to 2005 [APC = 3.68%, 95% &lt;i&gt;CI&lt;/i&gt;: (3.49%, 3.87%)] and from 2015 to 2021 [APC=0.30%, 95%&lt;i&gt;CI&lt;/i&gt;: (0.19%, 0.40%)].Theagestandardized prevalence (&lt;i&gt;r&lt;/i&gt; = -0.17, &lt;i&gt;P&lt;/i&gt; &lt; 0.05), mortality (&lt;i&gt;r&lt;/i&gt; = -0.67, &lt;i&gt;P&lt;/i&gt; &lt; 0.05) and DALYs rates of cystic echinococcosis (&lt;i&gt;r&lt;/i&gt; = -0.60, &lt;i&gt;P&lt;/i&gt; &lt; 0.05) all correlated negatively with SDI across 21 geographical regions from 1990 to 2021, and the age-standardized mortality (&lt;i&gt;r&lt;/i&gt; = -0.61, &lt;i&gt;P&lt;/i&gt; &lt; 0.05) and DALYs rates (&lt;i&gt;r&lt;/i&gt; = -0.44, &lt;i&gt;P&lt;/i&gt; &lt; 0.05) both correlated negatively with SDI across 204 countries and territories in 2021. Frontier analysis revealed that the age-standardized DALYs rate of cystic echinococcosis was still not in line with the frontier in some high-SDI countries or territories. In addition, the global age-standardized prevalence was projected with the BAPC model to appear a tendency towards a rise among both men [estimated annual p","PeriodicalId":38874,"journal":{"name":"中国血吸虫病防治杂志","volume":"37 3","pages":"255-267"},"PeriodicalIF":0.0,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144745335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Prevalence of <i>Clonorchis sinensis</i> human infections in Congjiang County of Guizhou Province in 2023].","authors":"D She, S Cai, S Li, G Lin, Z Shi, C Wu, L He, L Lu","doi":"10.16250/j.32.1915.2024250","DOIUrl":"https://doi.org/10.16250/j.32.1915.2024250","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To investigate the prevalence of &lt;i&gt;Clonorchis sinensis&lt;/i&gt; human infections in Congjiang County, Guizhou Province in 2023, so as to provide insights into formulation of the clonorchiasis control strategy.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Congjiang County was divided into eastern, western, southern, northern and central areas according to the geographical locations, and one township was randomly sampled from each area. Then, each administrative village was randomly sampled from each township, and 200 permanent residents over 3 years of age were randomly sampled from each village. Participants' stool samples were collected for detection of &lt;i&gt;C. sinensis&lt;/i&gt; eggs with the Kato-Katz technique (two slides for each stool sample), and the prevalence and intensity of &lt;i&gt;C. sinensis&lt;/i&gt; infections were calculated. In addition, the risk factors of clonorchiasis were identified among participants using a questionnaire survey.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;A total of 1 001 residents were included, and the prevalence of &lt;i&gt;C. sinensis&lt;/i&gt; infections was 16.28% (163/1 001), with mild infections as the predominant category of infection intensity [73.01% (119/163)]. The prevalence rates of &lt;i&gt;C. sinensis&lt;/i&gt; human infections were 30.50% (61/200), 1.50% (3/200), 30.35% (61/201), 12.50% (25/200), and 6.50% (13/200) at five survey sites, respectively (χ&lt;sup&gt;2&lt;/sup&gt; = 107.03, &lt;i&gt;P&lt;/i&gt; &lt; 0.05), and there was a significant difference in the prevalence of &lt;i&gt;C. sinensis&lt;/i&gt; infections between men [22.44% (112/499)] and women [10.16% (51/502)] (χ&lt;sup&gt;2&lt;/sup&gt; = 27.71, &lt;i&gt;P&lt;/i&gt; &lt; 0.05). The prevalence of &lt;i&gt;C. sinensis&lt;/i&gt; infections was relatively high among participants at ages of 60 to 70 years [26.14% (23/88)], public servants [46.15% (6/13)], and Han ethnic participants [33.33% (5/15)]. The prevalence of &lt;i&gt;C. sinensis&lt;/i&gt; infections was higher among participants with a habit of consuming raw or un-dercooked freshwater fish and shrimp [22.06% (90/408)] than among those without the habit [12.31% (73/593)] (χ&lt;sup&gt;2&lt;/sup&gt; = 16.85, &lt;i&gt;P&lt;/i&gt; &lt; 0.05), and there was no significant difference in the prevalence of &lt;i&gt;C. sinensis&lt;/i&gt; infections between participants with [13.99% (41/293)] and without separation of raw and cooked chopping boards [17.23% (122/708)] (χ&lt;sup&gt;2&lt;/sup&gt; = 1.59, &lt;i&gt;P&lt;/i&gt; &gt; 0.05). In addition, the prevalence of &lt;i&gt;C. sinensis&lt;/i&gt; infections was 8.70% (2/23) and 16.46% (161/978) among participants with and without fever complicated by discomfort in the right upper abdomen during the past half year (χ&lt;sup&gt;2&lt;/sup&gt; = 0.99, &lt;i&gt;P&lt;/i&gt; &gt; 0.05).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;The prevalence of &lt;i&gt;C. sinensis&lt;/i&gt; human infections was high in Congjiang County, Guizhou Province in 2023, and infections predominantly occurred among young and middle-aged men. Intensified health education among high-risk residents and alteration of dietary habits of consuming raw or undercooked freshwater fish or shrimp are recommended to reduce the","PeriodicalId":38874,"journal":{"name":"中国血吸虫病防治杂志","volume":"38 1","pages":"92-95"},"PeriodicalIF":0.0,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147784193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Feasibility of the spatiotemporal filtering model for analyzing the spatiotemporal distribution of reported schistosomiasis cases].","authors":"J Xu, Z Wang, F Gao, Z Zhang","doi":"10.16250/j.32.1915.2024270","DOIUrl":"https://doi.org/10.16250/j.32.1915.2024270","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the feasibility of the spatiotemporal filtering model in analysis of reported schistosomiasis cases, so as to provide insights into analysis of complicated data pertaining to schistosomiasis control.</p><p><strong>Methods: </strong>Demographic and epidemiological data of reported schistosomiasis cases in Anhui Province from 1997 to 2010 were collected from Anhui Provincial Center for Disease Control and Prevention, and the annual prevalence of <i>Schistosoma japonicum</i> human infections was calculated. The meteorological data were captured from meteorological stations in counties (cities, districts) of Anhui Province where schistosomiasis cases were reported from 1997 to 2010 at the National Meteorological Information Center, including monthly average air temperature and precipitation. Meteorological data were interpolated using the inverse-distance weighting method, and the annual average air temperature and annual precipitation were calculated in each county (city, district). The centroid of the county (city, district) where schistosomiasis cases were reported was extracted using the software ArcGIS 10.0, and the Euclidean distance from each centroid to the Yangtze River was calculated as the distance between that county (city, district) and the Yangtze River. The global Moran's <i>I</i> of the prevalence of <i>S. japonicum</i> human infections in Anhui Province for each year from 1997 to 2010 were calculated to analyze the spatial autocorrelation. A spatial weight matrix was constructed using Rook adjacency, and a first-order temporal weight matrix was built to quantify the relationship between disease changes over time. Subsequently, a spatiotemporal structure matrix was constructed. A negative binomial model was built based on the spatiotemporal structure matrix and data pertaining to reported schistosomiasis cases, and a linear model was created between the residual of the model and candidate set feature vectors to determine the optimal subset composition of the spatiotemporal filter through stepwise regression. Then, a spatio-temporal filtering model was constructed using the negative binomial model. Negative binomial models, Bayesian spatial models, and Bayesian spatiotemporal models were constructed and compared with the spatiotemporal filtering model to validate the performance of the spatiotemporal filtering model, and cross-validation was conducted for each model. The goodness of fit was evaluated using the deviance information criterion (DIC) and Watanabe-Akaike information criterion (WAIC), and the effectiveness of model validation was assessed using mean squared error (MSE), while the accuracy of assessment results was assessed using coefficients and their 95% confidence intervals (<i>CI</i>), and the computational efficiency was assessed based on the running time of the model. The four feature vectors with the largest Moran's <i>I</i> values were selected to identify regions with aut","PeriodicalId":38874,"journal":{"name":"中国血吸虫病防治杂志","volume":"37 3","pages":"232-238"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144745339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Evaluation of surgical efficacy in patients with hepatic cystic echinococcosis in Gansu Province from 2006 to 2023].","authors":"X Cheng, Y Feng, X Wang, Z Wang, J Lei, M Jiang, G Yang, X Zhang, S Yang, L Wang","doi":"10.16250/j.32.1915.2025016","DOIUrl":"https://doi.org/10.16250/j.32.1915.2025016","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the therapeutic efficacy for surgical treatments among patients with hepatic cystic echinococcosis in Gansu Province from 2006 to 2023, so as to provide insights into optimization of the diagnosis and treatment strategies against hepatic cystic echinococcosis.</p><p><strong>Methods: </strong>The demographic and clinical data of all echinococcosis cases included in central government fiscal transfer payment program for echinococcosis control and undergoing surgical treatments in Gansu Province from 2006 to 2023 were captured. Hepatic cystic echinococcosis patients with complete medical records and follow-up data were included in the study, and patients' characteristics, including hospital where patients received diagnosis and treatment, methods of case identification, year of surgery, classification of lesions, number of lesions, size of lesions, course of disease, surgical methods, and post-surgical follow-up data. The cure and recurrence of hepatic cystic echinococcosis were evaluated according to the <i>Guidelines for Management of Echinococcosis Patients in the Central Government Fiscal Transfer Payment Program</i>, and the cure and recurrent rates were calculated.</p><p><strong>Results: </strong>Data were collected from 1 686 surgical patients with hepatic cystic echinococcosis. According to the inclusion and exclusion criteria, 1 222 hepatic cystic echinococcosis patients undergoing surgical treatments were included during the period from 2006 to 2022, including 1 166 cured patients (95.42%) and 88 patients with postsurgical recurrence (7.20%), and the cure rate of surgical treatments appeared a tendency towards a rise among patients with hepatic cystic echinococcosis from 2008 to 2022 (χ²_trend = 19.39, <i>P</i> < 0.05). The cure rates of hepatic cystic echinococcosis were 100% (177/177), 94.81% (128/135) and 94.62% (861/910) among patients detected through regular physical examinations, screened by the central government fiscal transfer payment program for echinococcosis control, and those who passively sought healthcare services, respectively (χ² = 9.95, <i>P</i> < 0.05). The cure rates of hepatic cystic echinococcosis were 95.96% (1 046/1 090) among patients with a disease course of 2 years and less and 90.90% (120/132) among patients with a disease course of over 2 years (χ² = 6.87, <i>P</i> < 0.05), and there were significant differences in the cure rates among patients with hepatic cystic echinococcosis in terms of number of lesions (χ² = 24.44, <i>P</i> < 0.05) and surgical methods (<i>P</i> < 0.05). The cure rate of hepatic cystic echinococcosis patients was significantly higher following initiation of the central government fiscal transfer payment program for echinococcosis control (96.06%, 1 096/1 141) than before the program (86.42%, 70/81) (χ² = 16.06, <i>P</i> < 0.05), and the cure rate of hepatic cystic echinococcosis pa","PeriodicalId":38874,"journal":{"name":"中国血吸虫病防治杂志","volume":"37 3","pages":"247-254"},"PeriodicalIF":0.0,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144745338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}