中国血吸虫病防治杂志最新文献

{"title":"[Construction of a visual intelligent identification model for <i>Oncomelania hupensis robertsoni</i> in Yunnan Province based on the EfficientNet-B4 model].","authors":"S Bai, J Zhou, Y Dong, J Zhang, L Shi, K Yang","doi":"10.16250/j.32.1915.2024194","DOIUrl":"https://doi.org/10.16250/j.32.1915.2024194","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To construct a visual intelligent recognition model for &lt;i&gt;Oncomelania hupensis robertsoni&lt;/i&gt; in Yunnan Province based on the EfficientNet-B4 model, and to evaluate the impact of data augmentation methods and model hyperparameters on the recognition of &lt;i&gt;O. hupensis robertsoni&lt;/i&gt;.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A total of 400 &lt;i&gt;O. hupensis robertsoni&lt;/i&gt; and 400 &lt;i&gt;Tricula&lt;/i&gt; snails were collected from Yongsheng County, Yunnan Province in June 2024, and snail images were captured following identification and classification of 300 &lt;i&gt;O. hupensis robertsoni&lt;/i&gt; and 300 &lt;i&gt;Tricula&lt;/i&gt; snails. A total of 925 &lt;i&gt;O. hupensis robertsoni&lt;/i&gt; images and 1 062 &lt;i&gt;Tricula&lt;/i&gt; snail images were collected as a dataset and divided into a training set and a validation set at a ratio of 8:2, while 352 images captured from the remaining 100 &lt;i&gt;O. hupensis robertsoni&lt;/i&gt; and 354 images from the remaining 100 &lt;i&gt;Tricula&lt;/i&gt; snails served as an external test set. All acquired images were subjected to preprocessing, including cropping and resizing. Three data augmentation approaches were employed, including baseline, Mixup and Gaussian blurring, and model hyperparameters included two optimization algorithms of adaptive moment estimation (Adam) and stochastic gradient descent (SGD), two loss functions of focal loss and cross entropy loss, and two learning rate decay strategies of cosine annealing and multi-step. The intelligent recognition models of &lt;i&gt;O. hupensis robertsoni&lt;/i&gt; and &lt;i&gt;Tricula&lt;/i&gt; snails were constructed based on the EfficientNet-B4 model, and 7 training strategy groups were generated by combinations of different data augmentation approaches and hyperparameters. The performance of intelligent recognition models was tested with external test sets, and evaluated with accuracy, precision, recall, F1 score, loss, Youden's index, and the area under the receiver operating characteristic curve (AUC) under different training strategies.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The variation of loss values was comparable among intelligent recognition models with different data augmentation approaches. The Group 4 model constructed with Mixup and Gaussian blurring data augmentation approaches showed the optimal performance, with an accuracy of 90.38%, precision of 90.07%, F1 score of 89.44%, Youden's index of 0.81 and AUC of 0.961 in the external test set. The accuracy of models using the SGD optimizer reduced by 29.16% as compared to those using the Adam optimizer (χ&lt;sup&gt;2&lt;/sup&gt; = 81.325, &lt;i&gt;P&lt;/i&gt; &lt; 0.001), and the accuracy of models using the cross entropy loss function reduced by 0.80% as compared to the Group 4 model (χ&lt;sup&gt;2&lt;/sup&gt; = 3.147, &lt;i&gt;P&lt;/i&gt; &gt; 0.05), while the accuracy of models using the multi-step learning rate decay strategy increased by 0.65% as compared to the Group 4 model (χ&lt;sup&gt;2&lt;/sup&gt; = 0.208, &lt;i&gt;P&lt;/i&gt; &gt; 0.05). In addition, the model with the baseline + Mixup + Gaussianblurring data augmentation approach and hype","PeriodicalId":38874,"journal":{"name":"中国血吸虫病防治杂志","volume":"36 6","pages":"555-561"},"PeriodicalIF":0.0,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143013532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Progress of researches on mosquito salivary allergens].","authors":"S Jiang, X Zang, W Wang, S Hong","doi":"10.16250/j.32.1915.2024114","DOIUrl":"https://doi.org/10.16250/j.32.1915.2024114","url":null,"abstract":"<p><p>There are multiple bioactive substances in the mosquito saliva, most of which are allergic to humans. Previous studies have demonstrated that mosquito bites may induce allergic reactions mediated by B and T lymphocytes, resulting in a reduction in the quality of life and even death among patients. To date, 11 salivary allergens and 8 non-salivary allergens have been characterized in mosquitoes. Nevertheless, there is still lack of highly sensitive, highly specific and safe tools for diagnosis of mosquito bites-induced allergy, and the difficulty in obtaining natural mosquito salivary allergens results in failure in widespread applications of immunotherapy for mosquito bites-induced allergy. This review provides an overview of the allergic symptoms of mosquito bites and underlying mechanisms, and mosquito salivary allergens that have been characterized and registered in the systematic allergen nomenclature website.</p>","PeriodicalId":38874,"journal":{"name":"中国血吸虫病防治杂志","volume":"36 6","pages":"658-663"},"PeriodicalIF":0.0,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143013516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Application of artificial intelligence in parasitic diseases and parasitology].","authors":"Y Zhou","doi":"10.16250/j.32.1915.2024279","DOIUrl":"https://doi.org/10.16250/j.32.1915.2024279","url":null,"abstract":"<p><p>The rapid development of artificial intelligence poses a huge impact on health and has become a core driving force for the new generation of the scientific and technological revolution in the field of healthcare. Recently, artificial intelligence has been gradually applied in the field of parasitic diseases and parasitology, including disease diagnosis, prognosis prediction, prediction of transmission risk, intelligent identification of vectors and intermediate hosts, and disease prevention and control, which facilitates the progress towards elimination of parasitic diseases. In addition, artificial intelligence provides highly efficient tools and approaches for healthcare workers and researchers. This comment mainly reviews the application of artificial intelligence in the fields of parasitic diseases and parasitology.</p>","PeriodicalId":38874,"journal":{"name":"中国血吸虫病防治杂志","volume":"36 6","pages":"551-554"},"PeriodicalIF":0.0,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143013042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Prediction of areas of <i>Oncomelania hupensis</i> snail spread in Anhui Province based on five machine learning models].","authors":"F Gao","doi":"10.16250/j.32.1915.2024085","DOIUrl":"https://doi.org/10.16250/j.32.1915.2024085","url":null,"abstract":"<p><strong>Objective: </strong>To predict the areas of <i>Oncomelania hupensis</i> snail spread in Anhui Province from 1977 to 2023 using machine learning models, and to compare the effectiveness of different machine learning models for prediction of areas of <i>O. hupensis</i> snail spread, so as to provide insights into investigating the trends in areas of <i>O. hupensis</i> snail spread.</p><p><strong>Methods: </strong>Data pertaining to <i>O. hupensis</i> snail spread in Anhui Province from 1977 to 2023 were collected and a database was created. Five machine learning models were created using the software Matlab R2019b, including support vector regression (SVR), nonlinear autoregressive (NAR) neural network, back propagation (BP) neural network, gated recurrent unit (GRU) neural network and long short-term memory (LSTM) neural network models, and the model fitting effect was evaluated with mean absolute error (MAE), root mean squared error (RMSE) and coefficient of determination (<i>R</i>²). Following model training, the areas of <i>O. hupensis</i> snail spread were predicted in Anhui Province from 2024 to 2030.</p><p><strong>Results: </strong>The cumulative areas of <i>O. hupensis</i> snail spread were 40 241.32 hm² in Anhui Province from 1977 to 2023, and the area of <i>O. hupensis</i> snail spread varied greatly among years, with a periodic peak every 4 to 6 years. The fitting curves of SVR, NAR neural network, BP neural network, GRU neural network and LSTM neural network models were increasingly closer to the real curves for areas of <i>O. hupensis</i> snail spread in Anhui Province. The trends in areas of <i>O. hupensis</i> snail spread in Anhui Province from 2024 to 2030 appeared approximately \"M\"-shaped curves by SVR and NAR neural network models, approximately \"W\"-shaped curves by BP and GRU neural network models, and a unimodal conical curve by the LSTM neural network model. The LSTM neural network model had the best effect for predicting areas of <i>O. hupensis</i> snail spread in Anhui Province, with the RMSE of 1 277 480, MAE of 797 422 and <i>R</i>² of 0.978 9, respectively.</p><p><strong>Conclusions: </strong>Among the five models, The LSTM neural network model has a high efficiency for predicting areas of <i>O. hupensis</i> snail spread in Anhui Province, which may serve as a tool to investigate the trends in areas of <i>O. hupensis</i> snail spread.</p>","PeriodicalId":38874,"journal":{"name":"中国血吸虫病防治杂志","volume":"36 6","pages":"572-576"},"PeriodicalIF":0.0,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143013441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Prediction of potential geographic distribution of <i>Oncomelania hupensis</i> in Yunnan Province using random forest and maximum entropy models].","authors":"Z Zhang, C Du, Y Zhang, H Wang, J Song, J Zhou, L Wang, J Sun, M Shen, C Chen, H Jiang, J Yan, X Feng, W Wang, P Qian, J Xue, S Li, Y Dong","doi":"10.16250/j.32.1915.2024136","DOIUrl":"https://doi.org/10.16250/j.32.1915.2024136","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To predict the potential geographic distribution of &lt;i&gt;Oncomelania hupensis&lt;/i&gt; in Yunnan Province using random forest (RF) and maximum entropy (MaxEnt) models, so as to provide insights into &lt;i&gt;O. hupensis&lt;/i&gt; surveillance and control in Yunnan Province.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;The &lt;i&gt;O. hupensis&lt;/i&gt; snail survey data in Yunnan Province from 2015 to 2016 were collected and converted into &lt;i&gt;O. hupensis&lt;/i&gt; snail distribution site data. Data of 22 environmental variables in Yunnan Province were collected, including twelve climate variables (annual potential evapotranspiration, annual mean ground surface temperature, annual precipitation, annual mean air pressure, annual mean relative humidity, annual sunshine duration, annual mean air temperature, annual mean wind speed, ≥ 0 ℃ annual accumulated temperature, ≥ 10 ℃ annual accumulated temperature, aridity and index of moisture), eight geographical variables (normalized difference vegetation index, landform type, land use type, altitude, soil type, soil textureclay content, soil texture-sand content and soil texture-silt content) and two population and economic variables (gross domestic product and population). Variables were screened with Pearson correlation test and variance inflation factor (VIF) test. The RF and MaxEnt models and the ensemble model were created using the biomod2 package of the software R 4.2.1, and the potential distribution of &lt;i&gt;O. hupensis&lt;/i&gt; snails after 2016 was predicted in Yunnan Province. The predictive effects of models were evaluated through cross-validation and independent tests, and the area under the receiver operating characteristic curve (AUC), true skill statistics (TSS) and &lt;i&gt;Kappa&lt;/i&gt; statistics were used for model evaluation. In addition, the importance of environmental variables was analyzed, the contribution of environmental variables output by the models with AUC values of &gt; 0.950 and TSS values of &gt; 0.850 were selected for normalization processing, and the importance percentage of environmental variables was obtained to analyze the importance of environmental variables.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Data of 148 &lt;i&gt;O. hupensis&lt;/i&gt; snail distribution sites and 15 environmental variables were included in training sets of RF and MaxEnt models, and both RF and MaxEnt models had high predictive performance, with both mean AUC values of &gt; 0.900 and all mean TSS values and &lt;i&gt;Kappa&lt;/i&gt; values of &gt; 0.800, and significant differences in the AUC (&lt;i&gt;t&lt;/i&gt; = 19.862, &lt;i&gt;P&lt;/i&gt; &lt; 0.05), TSS (&lt;i&gt;t&lt;/i&gt; = 10.140, &lt;i&gt;P&lt;/i&gt; &lt; 0.05) and &lt;i&gt;Kappa&lt;/i&gt; values (&lt;i&gt;t&lt;/i&gt; = 10.237, &lt;i&gt;P&lt;/i&gt; &lt; 0.05) between two models. The AUC, TSS and &lt;i&gt;Kappa&lt;/i&gt; values of the ensemble model were 0.996, 0.954 and 0.920, respectively. Independent data verification showed that the AUC, TSS and &lt;i&gt;Kappa&lt;/i&gt; values of the RF model and the ensemble model were all 1, which still showed high performance in unknown data modeling, and the MaxEnt model showed poor ","PeriodicalId":38874,"journal":{"name":"中国血吸虫病防治杂志","volume":"36 6","pages":"562-571"},"PeriodicalIF":0.0,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143013375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Incidence and risk factors of anemia among newly reported HIV/AIDS patients in Jiangsu Province in 2021].","authors":"Z Zhang, Q Sun, T Qiu, P Ding, B Wang, B Zhu","doi":"10.16250/j.32.1915.2024174","DOIUrl":"https://doi.org/10.16250/j.32.1915.2024174","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To investigate the incidence of anemia and evaluate the immune status among newly reported HIV/AIDS patients in Jiangsu Province in 2021, and to identify the risk factors of anemia among patients living with HIV infections.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Newly reported HIV/AIDS patients in Jiangsu Province from January 1 to December 31, 2021 that were registered in China's National AIDS Comprehensive Control Information Management System were enrolled. Subjects' fresh whole blood samples were collected, and hemoglobin levels, CD4 and CD8 cell counts and HIV viral loads were measured. Anemia was defined according to hemoglobin levels, and the immunological parameters and HIV viral loads were compared between HIV-infected patients with and without anemia. The risk factors of anemia were identified among individuals living with HIV infections using univariate analysis and multivariate logistic regression analysis. In addition, subjects' CD4 cell counts one year following antiretroviral therapy (ART) were retrieved from China's National AIDS Comprehensive Control Information Management System, and compared between subjects with and without anemia.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;A total of 635 newly diagnosed HIV/AIDS patients were reported in Jiangsu Province in 2021, including 544 males (85.67%) and 91 females (14.33%), and with ages of 15 to 83 years, and the overall incidence of anemia was 5.51% (35/635) among the study subjects. Men, individuals at ages of 45 years and lower and workers had relatively higher hemoglobin levels, with median hemoglobin levels of 156 (interquartile range, 22), 154 (interquartile range, 23) g/L and 162 (interquartile range, 19) g/L, respectively. The median baseline HIV viral load was 40 500.00 (interquartile range, 119 735.00) copies/mL among HIV-infected individuals with anemia and 29 754.00 (69 183.00) copies/mL among those without anemia (&lt;i&gt;Z&lt;/i&gt; = -0.91, &lt;i&gt;P&lt;/i&gt; = 0.31), and the median baseline CD4 and CD8 cell counts were significantly lower among HIV-infected individuals with anemia [166 (interquartile range, 143) cells/μL and 755 (653) cells/μL] than those without anemia [308 (253) cells/μL and 892 (638) cells/μL] (&lt;i&gt;Z&lt;/i&gt; = -4.36 and -2.37, both &lt;i&gt;P&lt;/i&gt; values &lt; 0.05). The median CD4 cell counts remained lower among HIV-infected individuals with anemia than those without anemia [296 (interquartile range, 229) cells/μL vs. 457 (interquartile range, 313) cells/μL; &lt;i&gt;Z&lt;/i&gt; = -3.71, &lt;i&gt;P&lt;/i&gt; &lt; 0.05] one year following ART, and the proportions of moderate and severe immunosuppression were significantly higher among HIV-infected individuals with anemia (40.00% and 17.14%) than those without anemia (21.00% and 9.33%) (χ&lt;sup&gt;2&lt;/sup&gt; = 10.37 and 8.79, both &lt;i&gt;P&lt;/i&gt; values &lt; 0.01). Univariate analysis showed a higher detection rate of anemia among female HIV-infected individuals than among males [odds ratio (&lt;i&gt;OR&lt;/i&gt;) = 4.528, 95% confidence interval (&lt;i&gt;CI&lt;/i&gt;): (3.811, 5.245), &lt;","PeriodicalId":38874,"journal":{"name":"中国血吸虫病防治杂志","volume":"36 6","pages":"598-605"},"PeriodicalIF":0.0,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143013220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Physiological characteristics of <i>Bacillus thuringiensis</i> subspecies <i>israelensis</i> with double mutations of <i>cwlE</i> and <i>sigK</i> and its activity against larvae of <i>Culex pipiens pallens</i>].","authors":"L Huang, G Han, C Li, M Lin, N Zhang, J Xu","doi":"10.16250/j.32.1915.2024189","DOIUrl":"https://doi.org/10.16250/j.32.1915.2024189","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To investigate the physiological characteristics of &lt;i&gt;Bacillus thuringiensis&lt;/i&gt; subspecies &lt;i&gt;israelensis&lt;/i&gt; (Bti) with double mutations of &lt;i&gt;cwlE&lt;/i&gt; and &lt;i&gt;sigK&lt;/i&gt; genes and to assess the activity of Bti against larvae of &lt;i&gt;Culex pipiens pallens&lt;/i&gt; under different external factors, so as to provide the theoretical evidence for the use of engineered bacteria of Bti for effective mosquito control.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;&lt;i&gt;B. thuringiensis&lt;/i&gt; wild-type strain Bt-59 and Bt-59 strain with &lt;i&gt;cwlE&lt;/i&gt; mutation [Bt-59 (Δ&lt;i&gt;cwlE&lt;/i&gt;)] were cultured in nutrient broth media for 24 hours, and Bt-59 strains with &lt;i&gt;sigK&lt;/i&gt; mutation [Bt-59 (Δ&lt;i&gt;sigK&lt;/i&gt;)] and double mutations of &lt;i&gt;cwlE&lt;/i&gt; and &lt;i&gt;sigK&lt;/i&gt; [Bt-59 (Δ&lt;i&gt;cwlE-sigK&lt;/i&gt;)] were cultured in nutrient broth media for 48 hours. Then, 5 μL of culture media were transferred to glass sides, and cell morphology and mother cell lysis were observed under an optical microscope. The optical densities of Bti strain culture media were measured at different time points of culture, and the growth curves of Bt-59, Bt-59 (Δ&lt;i&gt;cwlE&lt;/i&gt;), Bt-59 (Δ&lt;i&gt;sigK&lt;/i&gt;), and Bt-59 (Δ&lt;i&gt;cwlE-sigK)&lt;/i&gt; strains were plotted. The differences in carbon source metabolism of four Bti strains were analyzed using the Biolog microplate culture method, and the metabolic activity of these strains was estimated with average well color development (AWCD). The fermentation media of these four Bti strains were diluted into final concentrations of 2.000, 1.000, 0.500, 0.250, and 0.125 μL/L, and the median lethal concentrations (LC&lt;sub&gt;50&lt;/sub&gt; values) of these four strains against the third instar larvae of &lt;i&gt;Cx. pipiens pallens&lt;/i&gt; were determined. In addition, the fermentation media of Bti strains were processed as follows: pH adjusted to 5, 7 and 9; treated at 30, 40 ℃ and 50 ℃ for 12 hours; and exposed to irradiation with ultraviolet lights for 0 hour and 6 hours. Then, 20 third instar larvae of &lt;i&gt;Cx. pipiens pallens&lt;/i&gt; were exposed to the above processed fermentation media at a final concentration of 1 μL/L in 200 mL of water at 26 ℃ for 24 hours, and the mosquito mortality was estimated to evaluate the effects of pH, temperature and ultraviolet irradiation on the larvicidal activity of four Bti strains.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The growth curves of the Bt-59 strain and its mutants shared a similar changing trend, and both experienced a stable phase 6 hours post-culture. Both spores and crystal proteins were found in Bt-59 and Bt-59 (Δ&lt;i&gt;cwlE&lt;/i&gt;) cells, and only crystal proteins were found in Bt-59 (Δ&lt;i&gt;sigK&lt;/i&gt;) and Bt-59 (Δ&lt;i&gt;cwlE-sigK&lt;/i&gt;) cells. No lysis was found in the cell wall of the Bt-59 (Δ&lt;i&gt;cwlE-sigK&lt;/i&gt;) strain, and the crystal protein was embedded in the mother cell. Biolog microplate culture assay showed that the AWCD values of four Bti strains showed a similar changing trend over time, and 33 carbon sources were found to be metabolized by all of the four strains,","PeriodicalId":38874,"journal":{"name":"中国血吸虫病防治杂志","volume":"36 6","pages":"606-613"},"PeriodicalIF":0.0,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143013229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Progress of researches on antiparasitic activities of scorpion venoms and their antimicrobial peptides].","authors":"","doi":"10.16250/j.32.1915.2024139","DOIUrl":"https://doi.org/10.16250/j.32.1915.2024139","url":null,"abstract":"<p><p>Scorpion venom is a highly complicated cocktail of bioactive components including mucoproteins, enzymes, lipids, bioactive peptides, and other organic or inorganic molecules. Scorpion venom antimicrobial peptides are a class of small-molecule bioactive peptides extracted from scorpion venoms, which have shown a variety of biological activities, including antiviral, antibacterial, antifungal and antitumor actions. This review describes the progress of researches on the antiparasitic activities of scorpion venoms and their antimicrobial peptides, so as to provide insights into the research and development of novel antiparasitic agents.</p>","PeriodicalId":38874,"journal":{"name":"中国血吸虫病防治杂志","volume":"36 6","pages":"649-657"},"PeriodicalIF":0.0,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143013512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Health education and health promotion during the progress towards schistosomiasis elimination Ⅰ Investigation on health education needs and available resource based on integration of community resources].","authors":"J Zhang, L Li, C Cao, S Xie, J Chen, Y Liu, H Xie, F Hu","doi":"10.16250/j.32.1915.2024117","DOIUrl":"https://doi.org/10.16250/j.32.1915.2024117","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To investigate the health education needs and available resources in schistosomiasis-endemic areas based on integration of community resources, and to explore the operation pathways for health education and promotion during the stage of schistosomiasis elimination.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A community was selected from Nanji Township, Xinjian District, Nanchang City, Jiangxi Province around the Poyang Lake areas as the study site, and a questionnaire survey on health education needs for schistosomiasis control was conducted among permanent residents at ages of 20 years in the community during the period between June and July, 2022 using face-to-face interviews. In addition, the resources available for the community-based schistosomiasis control health education were investigated among workers in township-level specialized institutions, members of civil society organizations, villagers, teachers and high and primary school students through field observations, field surveys and thematic interviews.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;A total of 304 individuals participated in the questionnaire survey on community-based health education needs for schistosomiasis control, and 94.41% (287/304) and 93.42% (284/304) of the respondents were most interested in knowing/understanding knowledge of the morphology of schistosomes and knowledge associated with the transmission route of schistosomiasis. The four most popular patterns for disseminating schistosomiasis control knowledge included live broadcasting of schistosomiasis control videos (94.41%, 287/304), printed brochures (89.80%, 273/304), special lectures by doctors (62.50%, 190/304) and physical health education materials for schistosomiasis control (61.51%, 187/304). There were 96.71% (294/304) and 77.63% (236/304) of respondents that accepted the participation of township healthcare center and township government/village committees in dissemination of schistosomiasis control knowledge, and there were 95.72% (291/304) and 80.59% (245/304) of respondents that mainly acquired schistosomiasis control knowledge through village allocation of leaflets and volunteer schistosomiasis control activities, respectively. There was 96.71% (294/304) of respondents participating in the dissemination activities of schistosomiasis control knowledge held by village committees, township healthcare centers, and high and primary schools/kinder-gartens, and 61.25% (177/289) of respondents were willing to participate in volunteer schistosomiasis control activities. A total of 115 individuals participated in the survey of available resources for community-based schistosomiasis control health education, and there were a large number of organizational, human and cultural resources in the community that were useful for health communication services.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;The abundant human and material resources from rural communities in schistosomiasis-endemic areas may be integ","PeriodicalId":38874,"journal":{"name":"中国血吸虫病防治杂志","volume":"36 6","pages":"626-630"},"PeriodicalIF":0.0,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143013240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Plasma exchange combined with continuous renal replacement therapy for imported severe <i>Plasmodium falciparum</i> malaria: a case report].","authors":"X Ma, B Li, X Yu, L Song, L Cheng","doi":"10.16250/j.32.1915.2024130","DOIUrl":"https://doi.org/10.16250/j.32.1915.2024130","url":null,"abstract":"<p><p>The article presents the diagnosis and treatment of an imported case with severe <i>Plasmodium falciparum</i> malaria, and the effect of plasma exchange combined with continuous renal replacement therapy. Severe <i>P. falciparum</i> malaria is characterized by complex clinical symptoms and multiple complications, and plasma exchange combined with continuous renal replacement therapy has a satisfactory therapeutic efficacy for severe <i>P. falciparum</i> malaria.</p>","PeriodicalId":38874,"journal":{"name":"中国血吸虫病防治杂志","volume":"36 6","pages":"664-666"},"PeriodicalIF":0.0,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143013315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}