Revista de la Facultad de Ciencias Medicas de Cordoba最新文献

{"title":"Multimodal imaging in the diagnosis of intramyocardial dissecting hematoma","authors":"Pablo Vadillo Martín, Juan Francisco Cueva Recalde, Pablo Revilla Martí, Juan Ramón Y Cajal Calvo, David Ibáñez Muñoz, José Ramón Ruiz Arroyo","doi":"10.31053/1853.0605.v83.n2.49724","DOIUrl":"10.31053/1853.0605.v83.n2.49724","url":null,"abstract":"<p><strong>Objective: </strong>To describe the diagnostic and therapeutic approach to a case of intramyocardial dissecting hematoma (IDH), a rare complication of acute myocardial infarction, highlighting the value of multimodal imaging in its identification and management.</p><p><strong>Case report: </strong>We present the case of a 50-year-old man who presented to the emergency department with chest pain and dyspnea of 12 hours duration. The electrocardiogram revealed an anterior myocardial infarction, and coronary angiography showed occlusion of the left anterior descending artery, which was treated with angioplasty. During hospitalization, transthoracic echocardiography revealed a hypoechoic mass at the apex, raising the differential diagnosis of intramyocardial hematoma, pseudoaneurysm, or mural thrombus. A cardiac computed tomography scan was performed, which ruled out complete rupture or pseudoaneurysm but did not allow for a definitive distinction. Subsequently, cardiac magnetic resonance imaging confirmed the presence of a hematoma contained within the myocardium, without epicardial rupture, and with surrounding areas of transmural fibrosis. Given the patient’s clinical stability and absence of signs of progression, an initial conservative treatment approach was chosen, with close clinical and imaging follow-up.</p><p><strong>Conclusion: </strong>IDH is a rare and potentially serious complication of acute myocardial infarction. Its diagnosis can be challenging and requires a multimodal approach. Cardiac magnetic resonance provides accurate tissue characterization that allows differentiation of intramyocardial dissecting hematoma from other similar entities and plays a key role in clinical decision-making. In stable patients, conservative management may be safe and effective.</p>","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"83 2","pages":"e49724"},"PeriodicalIF":0.0,"publicationDate":"2026-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13432253/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148362842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Steroid-Refractory Cutaneous Graft-versus-Host Disease: a Case Report","authors":"Sabrina Appeceix, Gabriel Vicente, Florencia Comacchio, Lucas Fernandez Otero","doi":"10.31053/1853.0605.v83.n2.50076","DOIUrl":"10.31053/1853.0605.v83.n2.50076","url":null,"abstract":"<p><p>Cutaneous graft-versus-host disease (cGVHD) is a potentially severe complication following allogeneic hematopoietic stem cell transplantation. We present the case of a 40-year-old woman with acute myeloid leukemia who underwent an allogeneic transplant with an HLA-matched unrelated donor. During the post-transplant phase, she developed steroid-refractory cutaneous GVHD, progressing to widespread lesions compatible with toxic epidermal necrolysis (NET-like). Management included second- and third-line therapies, such as JAK inhibitors (ruxolitinib), immunoglobulin, biological agents (infliximab, rituximab), and extracorporeal procedures (photopheresis and plasmapheresis). Early intervention and coordination by a multidisciplinary team allowed disease control and progressive improvement of the lesions. This case emphasizes the importance of early recognition of severe cutaneous GVHD, tailoring treatment according to disease severity and clinical response, and the need for a multidisciplinary approach to reduce morbidity and mortality.</p>","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"83 2","pages":"e50076"},"PeriodicalIF":0.0,"publicationDate":"2026-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13432002/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148362750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of strategies to prevent burnout syndrome in hospital-based healthcare personnel: an overview of systematic reviews","authors":"Matías Agustín Atencio, Joaquin Andrés Luini, Rocío Belén Cappella, Luciana Mattei, Candela Victoria Giuffre, Julieta Pereyra Huertas, Melina Paula Scherñuk Schroh, Nicolle Stefanía Davit Baridón, Candela Boscardin, María Eugenia Esandi, Lucas Gonzalo Duran","doi":"10.31053/1853.0605.v83.n2.49503","DOIUrl":"10.31053/1853.0605.v83.n2.49503","url":null,"abstract":"<p><strong>Introduction: </strong>Burnout syndrome (BO) significantly affects healthcare personnel, especially in hospital settings. The COVID-19 pandemic has intensified this issue, highlighting the need for effective preventive strategies.</p><p><strong>Objectives: </strong>To synthesize available evidence on the effectiveness of individual, organizational, and combined strategies to prevent or reduce BO in hospital-based healthcare personnel.</p><p><strong>Materials and methods: </strong>A systematic search was conducted in PubMed, Cochrane Library, Epistemonikos, and the Virtual Health Library for systematic reviews published between January 1, 2014, and January 15, 2024. Reviews with or without meta-analyses were included if they evaluated preventive interventions for BO and contained at least one primary study. Reviews focused solely on stress, well-being, or anxiety without specific BO outcomes were excluded. Two reviewers independently extracted data on study characteristics, types of interventions, measurement tools, and outcomes. A de novo extraction of 107 primary studies was also performed.</p><p><strong>Results: </strong>Twenty-seven systematic reviews were included. The most frequently evaluated interventions were mindfulness, cognitive-behavioral therapy, workload reduction, and professional coaching. Structured, in-person interventions generally showed greater effectiveness. Organizational strategies yielded mixed results.</p><p><strong>Conclusion: </strong>Both individual and organizational interventions can reduce BO in healthcare professionals. Structured, face-to-face, and multifaceted approaches appear to be more effective. High-quality research is needed, with emphasis on implementation strategies tailored to clinical contexts.</p>","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"83 2","pages":"e49503"},"PeriodicalIF":0.0,"publicationDate":"2026-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13432252/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148362820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical tumor lysis syndrome associated with elranatamab in relapsed multiple myeloma: a case report","authors":"Martín Milanesio, Julieta Olmedo, Gastón Caeiro, Ana Lisa Basquiera","doi":"10.31053/1853.0605.v83.n1.49234","DOIUrl":"10.31053/1853.0605.v83.n1.49234","url":null,"abstract":"<p><strong>Introduction: </strong>Multiple Myeloma (MM) is currently an incurable disease, with constant relapses and the need for multiple lines of treatment. Immune therapies, which include bispecific antibodies such as elranatamab, are a new option for the treatment of patients with relapsed/refractory MM (R/R MM), with high effectiveness, but not free of adverse reactions. Tumor lysis syndrome (TLS) is a rare complication of MM treatment and has not been reported after application of elranatamab.</p><p><strong>Case presentation: </strong>We report the case of a man with R/R MM who presented TLS after application of the first dose of elranatamab. The TLS resolved after supportive measures without subsequent recurrence.</p><p><strong>Conclusion: </strong>TLS is an uncommon complication of MM treatment and could be triggered by bispecific antibodies.</p>","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"83 1","pages":"e49234"},"PeriodicalIF":0.0,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13127283/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147582075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Preventive and therapeutic dental care for people with various disabilities in Argentina]","authors":"Gabriela Izurieta, Horacio González, Oriana Pinto, Mabel Brunotto","doi":"10.31053/1853.0605.v83.n1.49073","DOIUrl":"10.31053/1853.0605.v83.n1.49073","url":null,"abstract":"<p><strong>Background: </strong>Inequalities in oral health care among people with disabilities are a global challenge. Objective: To determine the oral health status and the different preventive/therapeutic actions performed on patients with different types of disabilities.</p><p><strong>Materials and methods: </strong>A retrospective study of patients with disabilities, of both sexes, treated at the Interdisciplinary Dental Care Service for Patients with Disabilities, FO-UNC, between 2012 and 2023 (project approved by the Academic Research Council of the Faculty of Dentistry-UNC). Results:</p><p><strong>Results: </strong>Data were collected from n=193 patient medical records. 84.6% presented poor/fair oral hygiene. 28.6% had an anterior open bite, and the same percentage showed an anterior covered bite. Other pathologies observed were hypodontia, microdontia, and andontia. 4.92% presented incorrect phonation, and 21.3% atypical swallowing. A total of 2.17% had supernumerary teeth. The average number of missing, extracted, and filled caries per patient varied across different tooth surfaces; while the average number of extracted and filled caries was 4 cavities (range 0–18). Clean and motivation procedures were performed in 70% of cases. Other types of dental treatments included extractions, root canals, and dental surgeries. Eighty-five percent of patients attended care for only half or less of a visit.</p><p><strong>Conclusions: </strong>Patients with disabilities presented with poor oral health, including a high number of cavities and poor oral hygiene. Many of them are probably unable to adequately follow the dentist's instructions, either due to economic or accessibility issues, or because the underlying pathology itself has worsened.</p>","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"83 1","pages":"e49073"},"PeriodicalIF":0.0,"publicationDate":"2026-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13127278/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147581983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The risk of choosing a residency in Health Sciences: a narrative review of key factors in decision-making]","authors":"Marcelo García Dieguez, Maria Nardi, Roberta Ladenheim","doi":"10.31053/1853.0605.v83.n1.49279","DOIUrl":"10.31053/1853.0605.v83.n1.49279","url":null,"abstract":"<p><strong>Objective: </strong>To analyze the main factors influencing the choice of a health sciences residency from a risk perspective, in order to provide a conceptual framework that supports informed decision-making among individuals beginning their postgraduate training.</p><p><strong>Methods: </strong>A narrative review of the literature published between 2000 and 2024 was conducted in Spanish and English, using searches in databases such as Medline and Latindex, as well as in official documents and institutional websites. An inductive thematic categorization strategy was applied, identifying six analytical dimensions of risk. The process was carried out independently by the authors, following the ethical guidelines of the Declaration of Helsinki and SANRA criteria.</p><p><strong>Results: </strong>The analysis identified six key components of perceived risk when choosing a residency: remuneration, institutional history, program structure, level of satisfaction, geographic location, and training opportunities. Each of these aspects entails specific advantages and challenges that must be evaluated by those in the selection process. The review provides practical tools and useful information to guide this decision.</p><p><strong>Conclusion: </strong>Choosing a health sciences residency is a complex process involving multiple risks. Understanding and critically analyzing the factors involved—based on diverse and reliable sources—helps reduce uncertainty and supports decisions that better align with personal and professional expectations. The proposed approach may serve as a guide for applicants, mentors, and institutional decision-makers.</p>","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"83 1","pages":"e49279"},"PeriodicalIF":0.0,"publicationDate":"2026-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13127279/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147582206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maxillary odontogenic myxoma: diagnostic and therapeutic insights of two case reports with management algorithm","authors":"Federico Garola, Carlos Marcelo Cerullo, Ezequiel Santalla Claros, Gastón Leonel Paladino, Julio César Garzón","doi":"10.31053/1853.0605.v83.n1.48964","DOIUrl":"10.31053/1853.0605.v83.n1.48964","url":null,"abstract":"<p><strong>Objective: </strong>To describe the clinical presentation, surgical management, and reconstruction of maxillary odontogenic myxomas through two case reports, and to propose a comprehensive management algorithm to guide diagnosis and treatment decisions.</p><p><strong>Case presentation: </strong>This study reports two cases treated at Piñero Hospital with resection and reconstruction using temporalis muscle flaps. Diagnosis was confirmed by clinical, radiological, and histopathological examinations. The first case involved a 36-year-old female with a multilobulated osteolytic lesion in the upper jaw; follow-up at 27 months showed no recurrence. The second case, a 27-year-old male, presented a large, aggressive osteolytic lesion; 32-month follow-up demonstrated successful healing without relapse.</p><p><strong>Conclusion: </strong>Maxillary odontogenic myxomas require individualized, multidisciplinary management. The proposed algorithm, integrating tumor size, extension, surgical approaches, and reconstruction options, offers a practical decision-making tool to improve clinical outcomes.</p>","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"83 1","pages":"e48964"},"PeriodicalIF":0.0,"publicationDate":"2026-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13127280/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147582459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Performance of prognostic scores during the first and second waves of COVID-19 pneumonia]","authors":"Santiago María Tomás Reyna, Melani Zlotogora, María Antonella Correa Barovero, Milagros Wendebourg, Hernán Badariotti, Valentina Cavalli Alessandria, Matías Roggero, Ricardo Venencia, Giuliana Torino, Constanza Cravero, Nicole Marie Kahn, Paula De Leonardi, Silvina Rodríguez Bonazzi, Ayelén Tarditi, Augusto Douthat Barrionuevo, Sofía María Villada, Pehuén Fernández, Ricardo Arturo Albertini, Emanuel José Saad","doi":"10.31053/1853.0605.v83.n1.49105","DOIUrl":"10.31053/1853.0605.v83.n1.49105","url":null,"abstract":"<p><strong>Introduction: </strong>Risk stratification in COVID-19 is crucial. We aimed to evaluate and compare the performance of prognostic scores for their respective endpoints (mortality or progression to severity) in hospitalized patients during the first and second pandemic waves in Córdoba, Argentina.</p><p><strong>Materials and methods: </strong>A retrospective cohort study was conducted in a tertiary care hospital. We included adults with COVID-19 pneumonia, comparing outcomes between the first (Mar/2020-Feb/2021) and second wave (Mar/2021-Dec/2021). The discrimination of each score for its specific endpoint (28/30-day mortality or progression) was assessed by ROC analysis.</p><p><strong>Results: </strong>Of 1176 patients, 30-day mortality was lower in the second wave (16.9% vs 28.8%; p<0.001). The 4C Score and PSI/PORT showed the best and most stable discrimination for mortality (AUC ~0.84) across both waves. In patients without initial severe disease, the CALL Score demonstrated acceptable discrimination for predicting progression to severity (AUC 1st wave: 0.71; 2nd wave: 0.67).</p><p><strong>Conclusion: </strong>Prognostic scores for mortality (4C, PSI/PORT) and for progression (CALL Score) maintained their clinical validity across different pandemic waves. They proved to be robust tools for risk stratification according to their respective endpoints, despite changes in patient profiles and vaccination status.</p>","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"83 1","pages":"e49105"},"PeriodicalIF":0.0,"publicationDate":"2026-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13127277/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147582480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Eccrine porocarcinoma on the dorsum of the foot: case report of a rare tumor]","authors":"Juana Sanguinetti, Lía Salomé Abeledo, María Walker, Javier Anaya, Corina Busso","doi":"10.31053/1853.0605.v83.n1.48849","DOIUrl":"10.31053/1853.0605.v83.n1.48849","url":null,"abstract":"<p><strong>Objectives: </strong>Eccrine porocarcinoma is a rare malignant adnexal tumor derived from the eccrine sweat glands, with metastatic potential. It primarily affects elderly individuals, and its most common location is in the head and neck region. Clinically, it presents as a solitary, nodular, erythematous-violaceous tumor. Its diagnosis can be challenging due to its clinical and histopathological variability. The objective of this case report is to describe a case of eccrine porocarcinoma in an unusual location and analyze its diagnostic and therapeutic approach.</p><p><strong>Case report: </strong>We present the case of a 59-year-old male patient who sought medical attention due to an asymptomatic lesion on the dorsum of the right foot, evolving over three months. On physical examination, a 1.5 cm diameter tumor with a brownish coloration and lobulated exophytic appearance was observed. Dermoscopy revealed erythematous and whitish areas. An incisional biopsy was performed, and histopathological analysis revealed an in situ porocarcinoma originating from a poroma. Immunohistochemistry confirmed positivity for EMA, CEA, and p63. A complete excision of the lesion was performed, with free margins and no evidence of recurrence to date.</p><p><strong>Conclusion: </strong>Eccrine porocarcinoma is a rare cutaneous neoplasm but has aggressive potential. Its diagnosis requires a comprehensive approach based on clinical evaluation, histopathology, and immunohistochemistry. Complete excision with free margins is the treatment of choice, although other therapies may be considered in advanced cases. Periodic follow-up is essential for early detection of recurrences and metastases.</p>","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"83 1","pages":"e48849"},"PeriodicalIF":0.0,"publicationDate":"2026-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13127281/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147582445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Rapidly involuting congenital hemangioma, diagnosed prenatally with heart failure and posnatal follow up]","authors":"Agustina Santarelli, María Candelaria Gimenez, María Dolores Salduna, Enrique Valente","doi":"10.31053/1853.0605.v83.n1.44679","DOIUrl":"10.31053/1853.0605.v83.n1.44679","url":null,"abstract":"<p><strong>Objectives: </strong>Describe the clinical case of a RICH that was diagnosed in uterus, normally in obstetric ultrasounds they are often confused with arteriovenous malformations and other congenital tumors. The differential diagnosis of these entities is important, since they have a different evolution, prognosis and treatment.</p><p><strong>Clinical case: </strong>The clinical case of a RICH with incipient signs of heart failure is presented, it required an interdisciplinary approach with dermatologists, neonatologists, obstetricians and specialists in diagnostic imaging, to define diagnosis, conduct and follow-up. Postnatal follow-up was performed until complete and spontaneous involution, leaving almost no sequelae, despite the large size of the tumor.</p><p><strong>Conclusion: </strong>It is important to take into consideration the diagnosis of RICH, among intrauterine high-flow vascular tumors, so as not to perform unnecessary interventions.</p>","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"83 1","pages":"e44679"},"PeriodicalIF":0.0,"publicationDate":"2026-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13127282/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147582457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}