Revista de la Facultad de Ciencias Medicas de Cordoba最新文献_第3页

[Dermatofibrosarcoma protuberans treated with Mohs surgery] 【莫氏手术治疗隆突性皮肤纤维肉瘤】

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2025-03-31 DOI: 10.31053/1853.0605.v82.n1.45363

Lía Salomé Abeledo, Carla Barbini, Gerardo Russier, Corina Busso

{"title":"[Dermatofibrosarcoma protuberans treated with Mohs surgery]","authors":"Lía Salomé Abeledo, Carla Barbini, Gerardo Russier, Corina Busso","doi":"10.31053/1853.0605.v82.n1.45363","DOIUrl":"10.31053/1853.0605.v82.n1.45363","url":null,"abstract":"Objetives: Dermatofibrosarcoma protuberans is a sarcomatous neoplasm with low incidence. It exhibits slow growth; however, it has the capacity to involve deep tissues. Clinically, it can mimic benign lesions, presenting as thickened or atrophic plaques that slowly transform into protruding lesions. The treatment of choice is surgical excision, with Mohs micrographic surgery standing out for its advantages.Clinical case: A 40-year-old male patient with dermatofibrosarcoma protuberans on the back underwent excision using the Mohs technique, with no tumor recurrence after two years of follow-up. Conclusion: It is important to highlight that the Mohs technique offers advantages over conventional methods, allowing for tissue optimization, ensuring clear margins, and achieving a low recurrence rateConclusion: It is important to highlight that the Mohs technique offers advantages over conventional methods, allowing for tissue optimization, ensuring clear margins, and achieving a low recurrence rate","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"82 1","pages":"165-175"},"PeriodicalIF":0.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12057716/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143755008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ophthalmoplegia as a Rare Initial Presentation of Cryptococcal Meningitis: A Case Report and Literature Review 双核间眼移植物作为隐球菌性脑膜炎的罕见初始表现。

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2025-03-31 DOI: 10.31053/1853.0605.v82.n1.44952

Raymundo Solís-Gómez, Itzel A Hernández-Dehesa, Aztlani Adan-Ruiz, Adrián F Sánchez-Cruz, Eduardo Argüelles-González

{"title":"Ophthalmoplegia as a Rare Initial Presentation of Cryptococcal Meningitis: A Case Report and Literature Review","authors":"Raymundo Solís-Gómez, Itzel A Hernández-Dehesa, Aztlani Adan-Ruiz, Adrián F Sánchez-Cruz, Eduardo Argüelles-González","doi":"10.31053/1853.0605.v82.n1.44952","DOIUrl":"10.31053/1853.0605.v82.n1.44952","url":null,"abstract":"Introduction: Cryptococcal meningitis (CM) frequently associates immunocompromised patients, specifically in HIV infection, and it has high mortality. Neuro-ophthalmic manifestations are rare in patients with CM, especially internuclear ophthalmoplegia (INO) or wall-eyed bilateral internuclear ophthalmoplegia (WEBINO), most of them the result of secondary vasculitis.Case report: A 53-year-old woman with chronic hepatic failure, had sudden drowsiness, diplopia, fever, and internuclear ophthalmoplegia. MRI showed generalized leptomeningeal enhancement plus infratentorial nodular enhancement type in the midbrain and left cerebellar hemisphere. An India ink test was positive for Cryptococcus neoformans.Conclusion: Cryptococcal meningitis causes a wide spectrum of neurological manifestations, but neuro-ophthalmological signs are infrequent. Physicians should consider that these meningitis events are capable of generating symptoms due to intra-axial involvement of the Central Nervous System (CNS) due to vasculitis.","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"82 1","pages":"176-187"},"PeriodicalIF":0.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12057709/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143755174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Hypoglycemia in a patient with pleural solitary fibrous tumor and response to pasireotide] [一例胸膜孤立性纤维性肿瘤患者的低血糖及对pasireotide的反应]

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2025-03-31 DOI: 10.31053/1853.0605.v82.n1.44424

Elizabeth Karen Videla, Pablo Ferrada, Jorge Miller, Eduardo Torres, Analía Álvarez, Javier Herrera, Bertha De la Torre

{"title":"[Hypoglycemia in a patient with pleural solitary fibrous tumor and response to pasireotide]","authors":"Elizabeth Karen Videla, Pablo Ferrada, Jorge Miller, Eduardo Torres, Analía Álvarez, Javier Herrera, Bertha De la Torre","doi":"10.31053/1853.0605.v82.n1.44424","DOIUrl":"10.31053/1853.0605.v82.n1.44424","url":null,"abstract":"Introduction: hypoglycemia is a common and multifactorial clinical condition. A rare cause is that associated with non-islet cell tumors.Objective: to report our experience on the management of severe hypoglycemia in a patient with solitary pleural fibrous tumor and his response to pasireotide.Clinical case: 63-year-old patient with a history of glomerulonephritis, hypothyroidism, arterial hypertension and a one-year diagnosis of solitary pleural fibrous tumor. Referred to endocrinology due to hypoglycemia for 6 months. Acromegaloid features were confirmed. Laboratory: Hct 36%, Hb 11.9 g/dl, GB 3570/mm3 (Eo 2%, Ba2%, Bac 4%, NS 36%, Li 30%, Mo 14% metamyelocytes 1%, myelocytes 11%), platelets 120,000 /mm3, ESR 10 mm, CRP 9 mg/L, TP 114%, TTPK 25 sec, blood glucose 57 mg/dL, renal function, hepatogram and lipid profile without particularities. IGF-1 84 ng/ml (VR 57 - 188), C-peptide 0.10 ng/ml (VR 1.10 - 4.40), somatotropin 0.98 ng/ml (VR up to 2.5) and basal insulin 0.4 uU/ml (VR 2.6 - 24) . IFG-2 measurement is not available in Argentina. A chest CT showed a pleural tumor measuring 13 cm. Without possibilities of surgical resection and without response to chemotherapy. Treatment was started with infusion of 25% dextrose, dexamethasone, pasireotide with good response. The patient died due to an infectious complication.Conclusion: pasireotide could be a therapeutic alternative in cases that are not candidates for surgery or refractory to other medical treatment.","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"82 1","pages":"127-139"},"PeriodicalIF":0.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12057705/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143754943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Incidence of acquired morbidity and its impact on patients in a pediatric intensive care unit based on the functional status scale] [基于功能状态量表的儿童重症监护病房患者获得性发病发生率及其影响]

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2025-03-31 DOI: 10.31053/1853.0605.v82.n1.45328

Judith Frydman, Mara Inés López

{"title":"[Incidence of acquired morbidity and its impact on patients in a pediatric intensive care unit based on the functional status scale]","authors":"Judith Frydman, Mara Inés López","doi":"10.31053/1853.0605.v82.n1.45328","DOIUrl":"10.31053/1853.0605.v82.n1.45328","url":null,"abstract":"Introduction: a significant number of children suffer cognitive, physical, mental and social limitations as a result of critical illnesses and their subsequent treatment. Pollack et al. developed the functional status scale with the purpose of measuring the change in functional status during hospitalization.Objectives: evaluate the acquired morbidity upon discharge from the Pediatric Intensive Care Unit (PICU). Specific objectives: compare mortality and acquired morbidity rates, analyze changes in functional status categories, identify the most affected domains, describe relationships between domain affection and admission diagnosis, between domain affection and age group, between morbidity and days in invasive mechanical ventilation (IMV), non-invasive ventilation and high-flow oxygen therapy.Methodology: observational, descriptive, prospective and longitudinal study. Patients between 1 and 180 months of age requiring ventilatory support for at least 48 hours, between February 2021 and February 2024, were included.Results: 90.9% survived, and of these, 26.9% developed acquired morbidity. The 42% of patients changed their functional status at least one point. The most affected domains were motor and feeding. Those who died had fewer days of IMV and hospitalization.Conclusion: The incidence of acquired morbidity was higher than mortality in the analyzed period. Children who developed morbidity remained hospitalized for a longer period of time and had greater requirements and days of IMV. Increased survival makes mortality an insufficient outcome metric. More studies with longer follow-up are needed.","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"82 1","pages":"41-60"},"PeriodicalIF":0.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12057707/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143755058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Advanced maternal age as a risk factor for adverse perinatal outcomes] 母亲年龄大是围产期不良结果的危险因素。

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2025-03-31 DOI: 10.31053/1853.0605.v82.n1.45349

Anyhely Yhoan Escudero Quispe, José Luis Vivanco Osorio

{"title":"[Advanced maternal age as a risk factor for adverse perinatal outcomes]","authors":"Anyhely Yhoan Escudero Quispe, José Luis Vivanco Osorio","doi":"10.31053/1853.0605.v82.n1.45349","DOIUrl":"10.31053/1853.0605.v82.n1.45349","url":null,"abstract":"This study finds a gradual increase in women's age at first pregnancy, a situation that has been associated with an increased risk of adverse maternal and postpartum events. While in the mid-1970s there were 1.7 per thousand pregnant nulliparous women between 35 and 39 years old, in 2012 this figure increased to 11 per thousand pregnant women, a six-fold increase. The global prevalence of pregnant women over 35 years of age is estimated at 12.3%. Maternal and perinatal characteristics and outcomes of nulliparous women aged 40 years and older are described and compared with characteristics of nulliparous women younger than 40 years. During the time of said study, approximately 4095 nulliparous female patients who met the inclusion criteria were treated; however, a limitation was found because it was a closed population treated in a highly complex tertiary hospital, the majority with high level of schooling and middle class socioeconomic level. In conclusion, older women constitute a high-risk population whose management and follow-up would require a different approach aimed at improving maternal and postpartum outcomes.","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"82 1","pages":"223-230"},"PeriodicalIF":0.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12057714/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143755144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Validation of a new impedance cardiography device for noninvasive hemodynamic measurement in outpatient hypertensive patients] [一种新型阻抗心电图仪在门诊高血压患者无创血流动力学测量中的验证]

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2025-03-31 DOI: 10.31053/1853.0605.v82.n1.45253

Marcelo A Rada, Paula Edit Cuffaro, María Celeste Szydlowicz, Verónica Andrea Peuchot, Margarita Susana Morales, Jorge Javier Janson, Ruben Micali, José Alfie, Carlos Rodolfo Galarza

{"title":"[Validation of a new impedance cardiography device for noninvasive hemodynamic measurement in outpatient hypertensive patients]","authors":"Marcelo A Rada, Paula Edit Cuffaro, María Celeste Szydlowicz, Verónica Andrea Peuchot, Margarita Susana Morales, Jorge Javier Janson, Ruben Micali, José Alfie, Carlos Rodolfo Galarza","doi":"10.31053/1853.0605.v82.n1.45253","DOIUrl":"10.31053/1853.0605.v82.n1.45253","url":null,"abstract":"Objective: To compare the new cardiograph ZLogic for non-invasive measurements of Stroke volume (SV) and Cardiac output (CO) against the Minnesota cardiograph.Methods: 86 subjects from both genders, 18-80 years old, hypertensive and healthy volunteers were included. Three hemodynamic measurements performed with each device, in an alternate fashion, using the Bland-Altman method to determine the level of agreement. Percentage error was calculated for interchangeability of both methods.Results: Mean SV was 86.71±27.35 mL and mean CO 5.42±1.74 L/min. There was a strong correlation between measures of SV and CO obtained with both devices (r=0.99, p<0.001). Mean difference (MD) for SV was 0.65±3.08 mL (CI95%: -0.01-1.31) and 95% limits of agreement −5.39 to +6.69 mL. MD for CO was 0.05±0.17 L/min (CI95%: 0.01-0.09) and the 95% limits of agreement −0.28 to +0.38 L/min.Conclusion: ZLogic and Minnesota cardiographs provided equivalent SV and CO values in ambulatory hypertensive patients.","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"82 1","pages":"95-109"},"PeriodicalIF":0.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12057702/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143755212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[ Accumulation of hyaluronic acid in rhinoseptoplasty: intraoperative finding] 鼻整形术中透明质酸的积累。

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2025-03-31 DOI: 10.31053/1853.0605.v82.n1.45169

Sebastián Abad-Cuenca, Xavier Eduardo Abad-González

引用次数: 0

[The implications of Argentina's withdrawal from the world health organization] [阿根廷退出世界卫生组织的影响]

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2025-03-31 DOI: 10.31053/1853.0605.v82.n1.48157

Eduardo Cuestas

引用次数: 0

[Long-term Titanium mesh cage implant failure after total en bloc spondylectomy due to spinal chondrosarcoma: case report and literature review] 脊柱软骨肉瘤全椎体切除术后长期钛网笼植入失败1例报告并文献复习

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2025-03-31 DOI: 10.31053/1853.0605.v82.n1.44999

María Belén Ginetti, Pablo Oyhamburu, Martín Bosio, Fernando Di Tullio

{"title":"[Long-term Titanium mesh cage implant failure after total en bloc spondylectomy due to spinal chondrosarcoma: case report and literature review]","authors":"María Belén Ginetti, Pablo Oyhamburu, Martín Bosio, Fernando Di Tullio","doi":"10.31053/1853.0605.v82.n1.44999","DOIUrl":"10.31053/1853.0605.v82.n1.44999","url":null,"abstract":"Objective: To report an unusual titanium mesh cage failure after ten years of follow-up.Clinical case: A 40-year-old woman diagnosed with low-grade spinal chondrosarcoma underwent a total en-bloc spondylenctomy (TES) surgery. This technique required a wide resection, anterior reconstruction with a titanium mesh cage (TMC), and posterior stabilization. For several years a favorable clinical outcome was achieved. After 10 years of follow-up, the patient developed acute non-traumatic low back pain without neurological repercussions. The images confirmed a rupture of the titanium cage. After ruling out tumor recurrence, the patient went through spinal instrumentation revision.Conclusion: Isolated TMC rupture is a rare event scarcely reported in the literature. There is a strong recommendation to instrument two levels proximal and distal to the bone defect in 360° reconstructions after a TES. Stability had likely been lost over the years due to the slow resorption of the bone graft. We consider necessary studies with a higher casuistry and level of evidence to analyze the contributing factors for the event of TMC rupture.","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"82 1","pages":"154-164"},"PeriodicalIF":0.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12057708/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143755173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Real-life study with pharmaceutical cannabidiol in refractory epilepsy] [药用大麻二酚治疗难治性癫痫的现实研究]

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2025-03-31 DOI: 10.31053/1853.0605.v82.n1.45350

Luis Angel Di Giuseppe, Juan Ignacio Appendino, María Del Carmen García, Karina Elena Alvarez, Gabriela Buela, Mariana Andrea Burgos, María Lourdes Posadas-Martínez, Maria Celeste Puga

{"title":"[Real-life study with pharmaceutical cannabidiol in refractory epilepsy]","authors":"Luis Angel Di Giuseppe, Juan Ignacio Appendino, María Del Carmen García, Karina Elena Alvarez, Gabriela Buela, Mariana Andrea Burgos, María Lourdes Posadas-Martínez, Maria Celeste Puga","doi":"10.31053/1853.0605.v82.n1.45350","DOIUrl":"10.31053/1853.0605.v82.n1.45350","url":null,"abstract":"Pharmaceutical-grade cannabidiol (CBD) is an alternative treatment for patients with drug-resistant epilepsy (DRE). In 2022, the Italian Hospital of Buenos Aires implemented a non-medical change (NMC) of treatment, replacing one commercial pharmaceutical-grade CBD product with another, the latter also being the initial option for new patients.Our objective was to evaluate the clinical outcomes of the commercial product change in this population.Methods: Retrospective cohort of DRE patients who either switched from one commercial pharmaceutical-grade CBD product to another or started treatment with the new product. The clinical response was evaluated by changes in seizure frequency, perception of change with the Patient Global Impression of Change (PGIC) scale, and safety considering discontinuation and/or the presence of adverse effects.Results: Nineteen patients were included, 12 in the change group and 7 in the new start group (7 pediatric and 12 adults). One patient discontinued treatment due to lack of response. Among those who completed follow-up, 8 (44%) reduced seizure frequency, 6 (33%) showed no change, and 4 (22%) increased seizure frequency. According to the PGIC scale, 9 (50%) remained unchanged, 5 (28%) reported barely noticeable changes, and 4 (22%) reported improvement. Adverse events were mild and transient.Conclusion: The new commercial pharmaceutical-grade CBD product is a safe and valid option both for substitution and initial treatment in patients with DRE. During the treatment period, patients perceived stability or improvement according to the PGIC scale.","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"82 1","pages":"110-126"},"PeriodicalIF":0.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12057711/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143755103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0