Comparison of the NUTRIC, NUTRICm and NUTRICpcr scores in critically ill patients ventilated for COVID-19.

Q3 Medicine

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2025-06-26 DOI:10.31053/1853.0605.v82.n2.43338

Claudina Luchitta, Dino Moretti, Daniel Horacio Bagilet, Nicolas Sebastian Rocchetti, Sheila Diodati, Silvana Paola Gattino, Melisa Debora Re, Claudio Jesus Settecase

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引用次数: 0

Abstract

Introduction: The COVID-19 pandemic caused a dramatic increase in ICU admissions due to severe acute respiratory syndrome. The NUTRIC score (with IL-6) and its variants NUTRICm (without IL-6) and NUTRICpcr (CRP instead of IL-6) were proposed to evaluate nutritional risk (RN) and even prognosis in critically ill patients.

Methods: Scores with inflammatory biomarkers (NUTRIC and NUTRICpcr) and without them (NUTRICm) were evaluated through a prospective and observational study to discriminate mortality and assess NB in patients ventilated for COVID-19.

Results: 418 patients were analyzed. The median (IQR) age and APACHE II were: 54 years (6-61) and 13 points (10-19). 79% died in the ICU. The highest agreement was between NUTRICm and NUTRICpcr (Kappa= 0.88). The AUCROC (95% CI) to discriminate mortality was: NUTRIC 0.661 (0.598-0.724), NUTRICpcr 0.635 (0.572-0.697) and NUTRICm 0.659 (0.596-0.722). The high RN classification showed differences between the scores with and without an inflammatory biomarker, being significant between NUTRIC and NUTRICm (14.6% vs 22.7%, p 0.0033).

Conclusion: In ventilated COVID-19 patients, the three nutritional risk scores studied discriminate mortality in a similar way, but the assessment of high NR differs between them, with a higher prevalence for the NUTRICm, which omits the inflammatory biomarker.

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危重重症COVID-19通气患者NUTRIC、NUTRICm和NUTRICpcr评分的比较

COVID-19大流行导致重症监护病房因严重急性呼吸综合征入院人数急剧增加。提出了NUTRIC评分（含IL-6）及其变体NUTRICm（不含IL-6）和NUTRICpcr （CRP代替IL-6）来评估危重患者的营养风险（RN）甚至预后。方法：通过前瞻性和观察性研究，评估有无炎症生物标志物（NUTRICm和NUTRICpcr）评分，以区分COVID-19通气患者的死亡率和NB。结果：共分析418例患者。中位（IQR）年龄和APACHE II分别为：54岁（6-61岁）和13分（10-19分）。79%死于重症监护室。NUTRICm和NUTRICpcr的一致性最高（Kappa= 0.88）。鉴别死亡率的AUCROC （95% CI）分别为：NUTRIC 0.661（0.598-0.724）、NUTRICpcr 0.635（0.572-0.697）和NUTRICm 0.659（0.596-0.722）。高RN分类在有无炎症生物标志物的评分中显示出差异，在NUTRIC和NUTRICm之间具有显著性（14.6%对22.7%,p 0.0033）。结论：在通气的COVID-19患者中，研究的三种营养风险评分区分死亡率的方式相似，但对高NR的评估不同，NUTRICm的患病率更高，而NUTRICm忽略了炎症生物标志物。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Revista de la Facultad de Ciencias Medicas de Cordoba Medicine-Medicine (all)

CiteScore

1.60

自引率

0.00%

发文量

审稿时长

20 weeks

期刊介绍： The Journal of the Faculty of Medical Sciences is a scientific publication of the Secretariat of Science and Technology of the Faculty of Medical Sciences of the National University of Cordoba. Its objective is to disseminate and promote research work related to Medical and Biological Sciences. It publishes scientific works of national and international professionals on different topics related to health sciences from the field of medicine, nursing, kinesiology, diagnostic imaging, phonoaudiology, nutrition, public health, chemical sciences, dentistry and related.