Revista de la Facultad de Ciencias Medicas de Cordoba最新文献

Variability in Human Immunodeficiency Virus infection screening: impact of the COVID-19 pandemic. 人类免疫缺陷病毒感染筛查的变异性：COVID-19大流行的影响

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2025-06-26 DOI: 10.31053/1853.0605.v82.n2.46015

Maximiliano Gabriel Castro, María José Sadonio, Ana Verónica Willa, Micaela Capeletti, Ana Paula Amato, Guillermina Cravero, Melina Beloso, Federico Rafael Galluccio

{"title":"Variability in Human Immunodeficiency Virus infection screening: impact of the COVID-19 pandemic.","authors":"Maximiliano Gabriel Castro, María José Sadonio, Ana Verónica Willa, Micaela Capeletti, Ana Paula Amato, Guillermina Cravero, Melina Beloso, Federico Rafael Galluccio","doi":"10.31053/1853.0605.v82.n2.46015","DOIUrl":"10.31053/1853.0605.v82.n2.46015","url":null,"abstract":"Introduction: Due to potential disruptions in HIV care services caused by COVID-19, this study aimed to evaluate the variability in HIV screening between 2019 and 2022 among adults hospitalized in the general ward of a tertiary care hospital in Santa Fe.Materials and methods: This ambispective and observational study evaluated the request for HIV serologic screening in patients selected through randomized sampling at a 2:1 ratio from October to December of the years 2019 to 2022. The impact of the COVID-19 pandemic during 2020 was compared to 2019, followed by the impact of an institutional intervention aimed at increasing the rate of HIV screening requests.Results: A total of 995 subjects were included. HIV screening was requested for 47.4% (n=472) of them, with a positivity rate of 1.7% (n=8). In 2020, HIV screening decreased compared to 2019 (34% vs. 43.9%, p<0.001), and increased to 84.2% in 2022 (p<0.001). In the multivariate analysis, the odds of HIV screening decreased with age (OR 0.986), while hospital admission in 2019 and 2022 (OR 1.48 y 9.76, respectively) increased it.Discussion: The COVID-19 pandemic exacerbated the already low rate of HIV screening requests, which was also influenced by the age of the subjects. However, through institutional guidelines, this situation was successfully reversed in 2022.","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"82 2","pages":"237-252"},"PeriodicalIF":0.0,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144545309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Medicines withdrawn in other countries due to safety problems, between 2014 and 2023, and their permanence in the Argentine market. 2014年至2023年期间，由于安全问题在其他国家撤回的药物，以及它们在阿根廷市场的持久性。

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2025-06-26 DOI: 10.31053/1853.0605.v82.n2.46049

Mariana Caffaratti, Martín Cañás, Daniel Eduardo Domosbian, Emiliano Giraudo, Ana María González, Andrea Lorenzo, Susana Núñez Montoya, María Teresa Rocha, María Luz Traverso, Sonia Uema

{"title":"Medicines withdrawn in other countries due to safety problems, between 2014 and 2023, and their permanence in the Argentine market.","authors":"Mariana Caffaratti, Martín Cañás, Daniel Eduardo Domosbian, Emiliano Giraudo, Ana María González, Andrea Lorenzo, Susana Núñez Montoya, María Teresa Rocha, María Luz Traverso, Sonia Uema","doi":"10.31053/1853.0605.v82.n2.46049","DOIUrl":"https://doi.org/10.31053/1853.0605.v82.n2.46049","url":null,"abstract":"Introduction: After the marketing approval of a medicine, pharmacovigilance monitoring must be carried out at an international level and the necessary measures must be adopted to reduce the risk that its use may present. Restrictive measures are not taken with the same speed in all countries and there are differences in withdrawal patterns.Objectives: Identify medicines that have been withdrawn from marketing for safety reasons in countries with health reference agencies (SRA), between January 2014 and June 2023. Establish if these medicines were withdrawn from the market in Argentina.Methodology: Search for information on SRA, National Administration of Food Drugs and Medical Technology (ANMAT) websites and secondary sources. For each medication withdrawn by any SRA, the validity of the marketing certificate and regulatory actions in Argentina were verified.Results: In countries with SRA health agencies, 31 medications were withdrawn for safety reasons. Of these, in Argentina, 7 were identified with a valid marketing certificate, another 7 were withdrawn from the market mostly by the manufacturing laboratories, 14 were never marketed and no data was obtained for 3.Conclusion: In Argentina, medications were identified that were withdrawn from other countries and continue to have a valid marketing certificate. The number of regulatory actions related to safety aspects in our country was lower than those of countries with SRA. It is necessary to strengthen the pharmacovigilance system, and for ANMAT to apply measures that reduce the risk associated with the use of the questioned medications.","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"82 2","pages":"253-270"},"PeriodicalIF":0.0,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144545275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nutritional information needs and search behaviors in argentine oncology patients 阿根廷肿瘤患者的营养信息需求和搜索行为

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2025-06-26 DOI: 10.31053/1853.0605.v82.n2.46283

Karen María Manzur, Ana Kohan Cortada

{"title":"Nutritional information needs and search behaviors in argentine oncology patients","authors":"Karen María Manzur, Ana Kohan Cortada","doi":"10.31053/1853.0605.v82.n2.46283","DOIUrl":"https://doi.org/10.31053/1853.0605.v82.n2.46283","url":null,"abstract":"Introduction: International scientific evidence highlights the growing need for nutritional information among oncology patients and their search behavior. However, in Argentina, the available information is limited.Objective: To describe the need for nutritional information and search behaviors among Argentine oncology patients in 2023.Methodology: Non-experimental, descriptive, cross-sectional design. A non-probabilistic sampling was used, and adult cancer patients who voluntarily gave their consent participated. A questionnaire was applied to evaluate the importance, need for nutritional information, search behavior, and perceived information overload. Data collection was conducted in a mixed manner, and statistical analysis was performed using SPSS software. A 95% confidence level was used.Results: A total of 500 patients participated; 87.2% (n=436) were women, and the most frequent diagnosis was breast cancer. 98% (n=490) emphasized the importance of receiving information about nutrition after diagnosis and during treatment, 91% (n=455) considered it a necessity, and 83.8% (n=419) reported having searched for information on this topic. This behavior was more frequent in patients with higher educational levels (p<0.05). The most consulted source was the internet, followed by doctors and nutritionists. 62% (n=310) agreed with the information overload regarding diet and cancer.Conclusion: These findings underscore the importance of meeting this information need and training healthcare professionals who care for this patient group.","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"82 2","pages":"303-317"},"PeriodicalIF":0.0,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144545276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Renal cell carcinoma metastasis to the thyroid gland after drug-induced thyroid dysfunction: case report. 药物性甲状腺功能障碍后肾细胞癌转移至甲状腺1例。

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2025-06-26 DOI: 10.31053/1853.0605.v82.n2.45462

Juan Bautista Del Valle, Julio Cesar Roa Garcia, Mauricio Arturo Osorio Montaño, Cristian Andres Echavarria Cadena, Jesica Lorena Savluk, Matías Adrián Borensztein

{"title":"Renal cell carcinoma metastasis to the thyroid gland after drug-induced thyroid dysfunction: case report.","authors":"Juan Bautista Del Valle, Julio Cesar Roa Garcia, Mauricio Arturo Osorio Montaño, Cristian Andres Echavarria Cadena, Jesica Lorena Savluk, Matías Adrián Borensztein","doi":"10.31053/1853.0605.v82.n2.45462","DOIUrl":"https://doi.org/10.31053/1853.0605.v82.n2.45462","url":null,"abstract":"Objective: Renal cell carcinoma may be associated with highly aggressive behavior and metastatic disease may be present in 30% of patients at the time of diagnosis. The most common sites of metastasis are the lungs, regional lymph nodes, liver, and bones. Metastases at rare sites include gums, larynx, nasal cavity, and thyroid gland. The objective of this article is to report an unusual manifestation of a known disease and present emerging technology useful in patient management.Clinical case: A 60-year-old male patient with a history of renal cell carcinoma. He initially received onco-specific treatment with nephrectomy and, ten years later, with zoledronate, pazopanib, and nivolumab due to metastatic progression. Four months after starting systemic treatment, drug-induced thyroid dysfunction was diagnosed, manifested by fatigue and abnormal laboratory results (TSH 9,23 uUI/mL). Due to the sensation of a lump in the neck, an ultrasound revealed a thyroid nodule on the right side.\u0000\u0000Aided by doppler ultrasound, and strain elastography, an ultrasound guided fine-needle aspiration biopsy of the thyroid nodule was performed, which confirmed metastasis of renal cell carcinoma.Conclusion: The emergence of a thyroid nodule in patients with a history of renal cell carcinoma and thyroid dysfunction could indicate oncological progression, even a long time after the initial diagnosis.","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"82 2","pages":"419-430"},"PeriodicalIF":0.0,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144545305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

SARS-CoV-2 circulation in pregnant women from central Argentina: mortality rate, infecting variants and a positive impact of the vaccine 阿根廷中部孕妇中SARS-CoV-2的传播：死亡率、感染变异和疫苗的积极影响

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2025-06-26 DOI: 10.31053/1853.0605.v82.n2.45927

Leticia D Augero, Gonzalo M Castro, Paola Sicilia, Eugenio Cecchetto, Laura Lopez, Graciela Scruzzi, Paula Barbero, Maria Del Pilar Diaz, Maria Gabriela Babas, Viviana Re, Maria Belen Pisano

{"title":"SARS-CoV-2 circulation in pregnant women from central Argentina: mortality rate, infecting variants and a positive impact of the vaccine","authors":"Leticia D Augero, Gonzalo M Castro, Paola Sicilia, Eugenio Cecchetto, Laura Lopez, Graciela Scruzzi, Paula Barbero, Maria Del Pilar Diaz, Maria Gabriela Babas, Viviana Re, Maria Belen Pisano","doi":"10.31053/1853.0605.v82.n2.45927","DOIUrl":"https://doi.org/10.31053/1853.0605.v82.n2.45927","url":null,"abstract":"Introduction: SARS-CoV-2 can lead to a more severe infection during pregnancy. However, population-level data on COVID-19 disease and vaccine uptake in this population group are lacking, especially in South America.Objective: We aimed to describe SARS-CoV-2 infection in pregnant women from a central region of Argentina.Methodology: From March-2020 to March-2022, 2407 cases of pregnant women from Córdoba province with confirmed SARS-CoV-2 infection reported in the official records were analyzed. The infectivity and mortality rates were calculated; a control group of non-pregnant women infected with SARS-CoV-2 was included. Sixty-six samples were subjected to variants of concern (VOC) detection by real time RT-PCR.Results: The overall infection rate was 0.25%, and the number of infections mirrored the number of cases for general population. In September-2021 (when mass vaccination in pregnant women occurred) the infection rate decreased (0.35% in March 2020-September 2021 vs. 0.14% in October 2021-March 2022). The global fatality rate was 0.75% (18/2407). During March-2020 to September-2021 the fatality rate was higher than in the control group: 1.01% vs. 0.08% (p<0.05). Since then, no deaths were recorded in pregnant women (fatality rate 0% vs. 0.01% in the control group). The VOCs distribution was: Gamma: 56%, Delta: 20%, Omicron: 12%, Alpha: 3%, 9% of non-VOC lineages.Conclusions: The fatality rate found was similar to that obtained for the entire country in this group, and higher than the control group. The frequency of VOCs reflected what happened in the general population. The decrease in cases and deaths since September-2021 correlated with the mass vaccination in this group.","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"82 2","pages":"287-302"},"PeriodicalIF":0.0,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144545306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Atypical presentation and unusual complications of appendicitis: a case report 阑尾炎的不典型表现及异常并发症1例

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2025-06-26 DOI: 10.31053/1853.0605.v82.n2.45332

Carolina Lucía Diego, Juliana Napoli, Jeremías Goransky

{"title":"Atypical presentation and unusual complications of appendicitis: a case report","authors":"Carolina Lucía Diego, Juliana Napoli, Jeremías Goransky","doi":"10.31053/1853.0605.v82.n2.45332","DOIUrl":"https://doi.org/10.31053/1853.0605.v82.n2.45332","url":null,"abstract":"Objective: To describe a case of acute appendicitis with an atypical presentation, complicated by hemoperitoneum, retroperitoneal hematoma, and pylephlebitis.Case report: A 55-year-old female patient without relevant history presented with 8 days of epigastric and right hypochondrial pain, fever, dark urine, and vasovagal syncope. Laboratory tests showed anemia, thrombocytopenia, liver dysfunction, and signs of sepsis. CT scan revealed an enlarged cecal appendix with wall disruption, portal and superior mesenteric vein thrombosis, and free fluid. Emergency laparoscopy was converted to laparotomy due to hemodynamic instability, revealing hemoperitoneum and retroperitoneal hematoma. Appendectomy, abdominal packing, and delayed closure were performed. The patient completed 19 days of antibiotic therapy, was transferred to the general ward on postoperative day 17, and discharged on day 20 with full recovery.Conclusion: Acute appendicitis complicated by hemoperitoneum, retroperitoneal hematoma, and pylephlebitis is rare but severe. Early diagnosis and appropriate surgical management are key to improving outcomes.","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"82 2","pages":"431-441"},"PeriodicalIF":0.0,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144545267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ERCP performed and described by surgical endoscopists. ERCP由外科内窥镜医师执行和描述。

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2025-06-26 DOI: 10.31053/1853.0605.v82.n2.45367

Ethan Craig, Carolina Jimenez, Robert Bowles, Jose Martinez, Robert Cubas

引用次数: 0

Comparison of the NUTRIC, NUTRICm and NUTRICpcr scores in critically ill patients ventilated for COVID-19. 危重重症COVID-19通气患者NUTRIC、NUTRICm和NUTRICpcr评分的比较

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2025-06-26 DOI: 10.31053/1853.0605.v82.n2.43338

Claudina Luchitta, Dino Moretti, Daniel Horacio Bagilet, Nicolas Sebastian Rocchetti, Sheila Diodati, Silvana Paola Gattino, Melisa Debora Re, Claudio Jesus Settecase

{"title":"Comparison of the NUTRIC, NUTRICm and NUTRICpcr scores in critically ill patients ventilated for COVID-19.","authors":"Claudina Luchitta, Dino Moretti, Daniel Horacio Bagilet, Nicolas Sebastian Rocchetti, Sheila Diodati, Silvana Paola Gattino, Melisa Debora Re, Claudio Jesus Settecase","doi":"10.31053/1853.0605.v82.n2.43338","DOIUrl":"https://doi.org/10.31053/1853.0605.v82.n2.43338","url":null,"abstract":"Introduction: The COVID-19 pandemic caused a dramatic increase in ICU admissions due to severe acute respiratory syndrome. The NUTRIC score (with IL-6) and its variants NUTRICm (without IL-6) and NUTRICpcr (CRP instead of IL-6) were proposed to evaluate nutritional risk (RN) and even prognosis in critically ill patients.Methods: Scores with inflammatory biomarkers (NUTRIC and NUTRICpcr) and without them (NUTRICm) were evaluated through a prospective and observational study to discriminate mortality and assess NB in patients ventilated for COVID-19.Results: 418 patients were analyzed. The median (IQR) age and APACHE II were: 54 years (6-61) and 13 points (10-19). 79% died in the ICU. The highest agreement was between NUTRICm and NUTRICpcr (Kappa= 0.88). The AUCROC (95% CI) to discriminate mortality was: NUTRIC 0.661 (0.598-0.724), NUTRICpcr 0.635 (0.572-0.697) and NUTRICm 0.659 (0.596-0.722). The high RN classification showed differences between the scores with and without an inflammatory biomarker, being significant between NUTRIC and NUTRICm (14.6% vs 22.7%, p 0.0033).Conclusion: In ventilated COVID-19 patients, the three nutritional risk scores studied discriminate mortality in a similar way, but the assessment of high NR differs between them, with a higher prevalence for the NUTRICm, which omits the inflammatory biomarker.","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"82 2","pages":"362-379"},"PeriodicalIF":0.0,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144545268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Factors associated with postpartum weight retention in women attending a public hospital in the Province of Buenos Aires. 布宜诺斯艾利斯省一家公立医院妇女产后体重潴留的相关因素。

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2025-06-26 DOI: 10.31053/1853.0605.v82.n2.45625

Lucia Torres, Lucrecia María Rosa Fotia Perniciaro, Ignacio Mendez, Agustina Malpeli, Ana Luz Kruger

{"title":"Factors associated with postpartum weight retention in women attending a public hospital in the Province of Buenos Aires.","authors":"Lucia Torres, Lucrecia María Rosa Fotia Perniciaro, Ignacio Mendez, Agustina Malpeli, Ana Luz Kruger","doi":"10.31053/1853.0605.v82.n2.45625","DOIUrl":"https://doi.org/10.31053/1853.0605.v82.n2.45625","url":null,"abstract":"Pregnancy carries the potential risk of developing and maintaining a nutritional status characterized by persistent obesity. This can be magnified when weight gains exceed established recommendations. This postpartum weight retention can significantly contribute to long-term excess weight and cardiovascular events.Objective: to describe weight retention at 3 and/or 6 months postpartum in women who consulted at the Pediatric Development and Research Institute (IDIP).Methodology: analytical, retrospective cross-sectional study. Data were collected from the medical records of women who underwent health check-ups at 3 and/or 6 months postpartum. Multiple linear regressions were performed relating postpartum weight retention to those conditioning factors.Results: The sample was made up of 257 women who underwent controls at 3 months and 577 at 6 months postpartum. Weight retention at 3 months postpartum was negatively associated with primiparity, higher level of education, newborn weight and exclusive breastfeeding, while at 6 months it was only found with these last two factors. Weight retention at 3 and 6 months was positively related to gestational weight gain.Conclusion: Postpartum weight retention increases influenced by weight gain during pregnancy, but primiparity, schooling, newborn weight and breastfeeding seem to be factors that contribute to reducing it.","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"82 2","pages":"271-286"},"PeriodicalIF":0.0,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144545272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Independent predictors of quality of life in patients with chronic heart failure. 慢性心力衰竭患者生活质量的独立预测因素。

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2025-06-26 DOI: 10.31053/1853.0605.v82.n2.45573

Lyda Z Rojas, Laura M Cabeza, Adriana M Jurado, Luis E Echeverría, Juliana Alexandra Hernández-Vargas, Silvia Juliana Trujillo-Cáceres

{"title":"Independent predictors of quality of life in patients with chronic heart failure.","authors":"Lyda Z Rojas, Laura M Cabeza, Adriana M Jurado, Luis E Echeverría, Juliana Alexandra Hernández-Vargas, Silvia Juliana Trujillo-Cáceres","doi":"10.31053/1853.0605.v82.n2.45573","DOIUrl":"https://doi.org/10.31053/1853.0605.v82.n2.45573","url":null,"abstract":"Introduction: Objective measurement of Health-Related Quality of Life (HRQoL) has proven useful in evaluating the effectiveness of medical management and its potential as a predictor of mortality and rehospitalization in patients with heart failure (HF). The aim of this study is to characterize HRQoL and determine its independent predictors in patients with chronic HF from a heart failure and transplant clinic in Colombia.Methods: This was an analytical cross-sectional study. The outcome variable was HRQoL measured using The Minnesota Living with Heart Failure Questionnaire (MLHFQ). Descriptive analysis of sociodemographic and clinical characteristics was conducted. Simple and multiple linear regressions were performed to establish predictors, considering statistical significance at p < 0.05.Results: A total of 200 patients were analyzed. 20% had Chagasic etiology. The median left ventricular ejection fraction (LVEF) was 30% (range 10 - 68%). The mean HRQoL score was 38.71 points (SD ± 22.67 points). \"Multivariate analysis identified seven independent predictors of worse HRQoL: age (β=0.17), low vs. high socioeconomic status (β=13.45), HF etiology, Chagas vs. others (β=12.97), number of hospitalizations in the last year (β=2.94), Charlson index (β=3.47), digitalis use (β=7.34), and NYHA functional class III-IV vs. I-II (β=28.04). Angiotensin-converting enzyme use was associated with better HRQoL (β=-4.80).Conclusion: This study shows that HRQoL in chronic HF is significantly determined by a set of socioeconomic, clinical, and management factors. The identification of these predictors underpins the need for comprehensive and personalized care strategies to improve the quality of life of these patients.","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"82 2","pages":"380-398"},"PeriodicalIF":0.0,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144545274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0