Revista de la Facultad de Ciencias Medicas de Cordoba最新文献_第2页

[Sleep disturbances in menopausal women. What do they say?: a cross-sectional study] 绝经后妇女睡眠中断的原因。他们说什么？

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2026-08-25 DOI: 10.31053/1853.0605.v83.n3.50008

Stella Maris Valiensi, Agustin Folgueira, Susana Pilnik, Agustina Starvaggi, María Alejandra Belardo

{"title":"[Sleep disturbances in menopausal women. What do they say?: a cross-sectional study]","authors":"Stella Maris Valiensi, Agustin Folgueira, Susana Pilnik, Agustina Starvaggi, María Alejandra Belardo","doi":"10.31053/1853.0605.v83.n3.50008","DOIUrl":"10.31053/1853.0605.v83.n3.50008","url":null,"abstract":"Few studies have investigated sleep quality in postmenopausal women and the causes that disrupt it. Objectives: Evaluate sleep quality and identify the reasons that interrupt them. To evaluate daytime sleepiness in the postmenopausal period and also to analyze the association of reasons that interrupt sleep with the time elapsed in the postmenopause Methods: Cross-sectional study. N=196 surveys were selected. Quality and reasons for sleep fragmentation were assessed using the Pittsburgh Sleep Quality Index and sleepiness by the Epworth Sleepiness Scale. Protocol approved by the Ethics and Research Committee. Results: 46.4% reported poor sleep quality. 65% reported nocturia, 61% having to wake up in the middle of the night and 57% feeling hot. More postmenopausal years were inversely associated with daytime sleepiness, p=0.02. Conclusion: We found poor sleep quality in 46.4% and the reasons frequently cited were nocturia, waking up in the middle of the night or early in the morning, having a feeling of heat and difficulty falling asleep in the first 30 minutes as causes of sleep fragmentation. Greater sleepiness was associated during the first years of postmenopause. The study allowed us to know certain aspects that motivate poor sleep quality, although it is possible to increase the n and plan actions to improve sleep in this menopause.","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"83 3","pages":"e50008"},"PeriodicalIF":0.0,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149082136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Maternal calcium intake during pregnancy and its impact on offspring blood pressure: identifying the optimal rat strain for mechanistic studies 孕妇孕期钙摄入量及其对子代血压的影响。

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2026-08-24 DOI: 10.31053/1853.0605.v83.n3.48803

Mercedes Lombarte, Laureana Villarreal, Agustina Velázquez, Verónica E Di Loreto, José Belizán, Alfredo Rigalli, Lucas R Brun

{"title":"Maternal calcium intake during pregnancy and its impact on offspring blood pressure: identifying the optimal rat strain for mechanistic studies","authors":"Mercedes Lombarte, Laureana Villarreal, Agustina Velázquez, Verónica E Di Loreto, José Belizán, Alfredo Rigalli, Lucas R Brun","doi":"10.31053/1853.0605.v83.n3.48803","DOIUrl":"10.31053/1853.0605.v83.n3.48803","url":null,"abstract":"Arterial hypertension is a major risk for disability and death globally. Hypertension is influenced by genetics, epigenetics and environmental factors. An inverse association between calcium intake and high blood pressure (BP) has been widely described. Several works have demonstrated that maternal calcium deficiency during pregnancy can lead to increased BP in offspring, highlighting the importance of maternal nutrition in foetal programming. Therefore, the aim of this review is to identify the most suitable rat strain for studying the effects of maternal calcium intake during pregnancy on offspring BP in adulthood. The literature search found articles involving Wistar, Sprague Dawley, and Wistar Kyoto rat strains. These strains are appropriate models for investigating the relationship between calcium intake and BP in normotensive rats. However, there is little evidence on the effects of calcium intake during pregnancy on offspring BP, suggesting the need of further research to elucidate the underlying mechanisms.","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"83 3","pages":"e48803"},"PeriodicalIF":0.0,"publicationDate":"2026-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149082200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ischemic stroke as the first manifestation of acute promyelocytic. 缺血性脑卒中为急性早幼粒细胞性白血病的首发表现。

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2026-08-24 DOI: 10.31053/1853.0605.v83.n3.50082

Malena Tarchini, María Laura Herrera Andino, Carlos Hernan Hollmann, Milagros López Orozco, María Emilia Más, Aldana Llorens, Natacha Brochero, Juan Manuel Rivoire, María Lourdes Argüello Zamarbide, Andrea Milagros Aballay, Brenda Nidia Ricchi, María Belén Fiora, Florencia Celeste Salazar, Yuliana Sofía Colussi, Andrea Alejandra Eckhardt, Emanuel José Saad

{"title":"Ischemic stroke as the first manifestation of acute promyelocytic.","authors":"Malena Tarchini, María Laura Herrera Andino, Carlos Hernan Hollmann, Milagros López Orozco, María Emilia Más, Aldana Llorens, Natacha Brochero, Juan Manuel Rivoire, María Lourdes Argüello Zamarbide, Andrea Milagros Aballay, Brenda Nidia Ricchi, María Belén Fiora, Florencia Celeste Salazar, Yuliana Sofía Colussi, Andrea Alejandra Eckhardt, Emanuel José Saad","doi":"10.31053/1853.0605.v83.n3.50082","DOIUrl":"10.31053/1853.0605.v83.n3.50082","url":null,"abstract":"Acute promyelocytic leukemia (APL) is a hematologic emergency characterized by a high risk of coagulopathy that can manifest with both severe bleeding and thrombotic events, including ischemic stroke. However, its initial presentation as large vessel arterial thrombosis is infrequent and potentially lethal. We report the case of a previously healthy 15-year-old female referred for suspected left frontal ischemic stroke with right spastic hemiplegia and expressive aphasia. One week earlier, she had presented with headache, nausea and transient episodes of paresthesias and weakness of the right hand and foot. Laboratory studies revealed bicytopenia (leukopenia and anemia), hypofibrinogenemia and elevated D-dimer. Imaging studies showed a subacute infarct in the left caudate nucleus and recent ischemia in the frontal cortex with complete occlusion of the left internal carotid artery. Bone marrow aspirate showed blast cells with Auer rods and strong positivity for myeloperoxidase. Flow cytometry revealed 41,2 % of cells with a phenotype compatible with promyelocytes, PML::RARA fusión gene was confirmed by molecular and cytogenetic studies. Immediate treatment with all-trans retinoic acid (ATRA), corticosteroids, and hemostatic support was initiated. Subsequently, the patient presented with a new occipital infarction and was started on anticoagulant therapy. She did well with motor and speech recovery. This case highlights the importance of considering APL as an underlying etiology of arterial thrombotic events in adolescents with cytopenias and coagulopathy, especially in the presence of major vessel occlusion, where early diagnosis and timely treatment are essential to reduce morbidity and mortality.","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"83 3","pages":"e50082"},"PeriodicalIF":0.0,"publicationDate":"2026-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149082195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Penicillin, an elixir to safeguard myocardial function in patients with rheumatic heart disease? 青霉素是保护风湿性心脏病患者心肌功能的灵丹妙药？

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2026-08-20 DOI: 10.31053/1853.0605.v83.n3.49984

Aryan Naghedi, Hasan Haghaninejad, Mohammadtaghi Sarebanhassanabadi, Seid Kazem Razavi-Ratki

{"title":"Penicillin, an elixir to safeguard myocardial function in patients with rheumatic heart disease?","authors":"Aryan Naghedi, Hasan Haghaninejad, Mohammadtaghi Sarebanhassanabadi, Seid Kazem Razavi-Ratki","doi":"10.31053/1853.0605.v83.n3.49984","DOIUrl":"10.31053/1853.0605.v83.n3.49984","url":null,"abstract":"Objective: Valvular heart diseases occur following different evitable and inevitable etiologies. Rheumatic valvular heart disease is among preventable etiologies and is almost disappeared in developed nations. In recent literature there are few low-quality evidences available about therapeutic efficacy of penicillin in maintaining and enhancing myocardial function in patients with rheumatic heart disease. In present study we aimed to investigate importance of penicillin in maintaining myocardial function indices within normal range.Methods: In this retrospective descriptive-analytic study we enrolled a number of 682 consecutive patients with rheumatic heart disease. Information about history of treatment with penicillin and associated details along with left ventricular ejection fraction and right ventricular systolic function were collected in a questionnaire. Finally, all data were analyzed using SPSS ver.26 software.Results: The study population consist of 471 (69.1%) women and 211 (30.9%) men with mean age of 51.17±12.80 years, ranged between 17 and 87. We found that there is a statistically significant association between history of penicillin treatment (P-value=0.036) and left ventricular ejection fraction. Right ventricular systolic function was affected by history of penicillin treatment (P-value=0.040) and duration of treatment (P-value=0.002).Conclusion: Rather than approved prophylactic effects of penicillin; we conclude that penicillin is also highly effective as a therapeutic agent in maintaining left ventricular ejection fraction and right ventricular systolic function within normal range in patients with rheumatic heart disease.","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"83 3","pages":"e49984"},"PeriodicalIF":0.0,"publicationDate":"2026-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149082146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Reactional episodes in lepromatous leprosy: presentation of a clinical case] 麻风病的反应性发作。

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2026-08-11 DOI: 10.31053/1853.0605.v83.n3.49582

Aldana Ayelén Assad, Ricardo Gastón Britos Fodor, Mariana Virginia Teberobsky, Gabriela Laura Arena

引用次数: 0

[Evaluation of an introductory course on research methodology for healthcare trainees: ten years of experience and curricular adaptations] 评估专业住院医师的研究方法入门课程。

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2026-08-06 DOI: 10.31053/1853.0605.v83.n3.49658

María Lourdes Posadas Martínez, Silvina Dell'Era, Marcelina Carretero, Sergio Adrián Terrasa

{"title":"[Evaluation of an introductory course on research methodology for healthcare trainees: ten years of experience and curricular adaptations]","authors":"María Lourdes Posadas Martínez, Silvina Dell'Era, Marcelina Carretero, Sergio Adrián Terrasa","doi":"10.31053/1853.0605.v83.n3.49658","DOIUrl":"10.31053/1853.0605.v83.n3.49658","url":null,"abstract":"Introduction: Critical biomedical reading is essential in the training of health professionals.Objectives: Narrate a decade of experience in the redesign and implementation of an introductory course on research methodology for health residents and fellows at a University Hospital.Methodology: The objective of the course is to acquire skills for critical reading and tools to plan research projects. The educational model evolved from face-to-face meetings and theoretical classes (2015-2018) to synchronous online (2019-2021) and finally to asynchronous online (2022-2024), incorporating new technological and hypermedia resources, offering greater flexibility and autonomy to the student. The type of evaluation was also modified, from individual multiple-choice and oral exams in small groups, with presentations on critical reading of biomedical literature, to a similar but synchronous format. Finally, they were replaced by individual activities with automatic feedback and an asynchronous activity in small groups where the analysis of the clinical research article is accompanied by questions that guide its interpretation, with personalized feedback. At the end of the course, a survey was sent to the participants to collect feedback and make continuous improvements to the program.1,073 participants were included, 66.1% women. There were no changes in the composition of the cohorts (sex and type of residence), 87.1% (95% CI 84.9 to 89.1%) completed and passed the course. An increasing and statistically significant trend was observed in the proportion of approved students from the 2015-2018 cohort to the 2022-2024 cohort (p < 0.001). The sustained increase in participants who completed and passed the course with the passing of the cohorts and the high satisfaction of the participants demonstrate the effectiveness of the methodological adaptations.","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"83 3","pages":"e49658"},"PeriodicalIF":0.0,"publicationDate":"2026-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149082080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Acute disseminated encephalomyelitis during the acute phase of meningitis caused by Streptococcus pneumoniae: a case report.] 在急性脑膜炎阶段由肺炎链球菌传播的急性脑脊液炎。

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2026-08-06 DOI: 10.31053/1853.0605.v83.n3.49438

Cecilia De Goycoechea, Maria Sol Groppo, Verónica Villarreal, Leonardo Meinarde

{"title":"[Acute disseminated encephalomyelitis during the acute phase of meningitis caused by Streptococcus pneumoniae: a case report.]","authors":"Cecilia De Goycoechea, Maria Sol Groppo, Verónica Villarreal, Leonardo Meinarde","doi":"10.31053/1853.0605.v83.n3.49438","DOIUrl":"10.31053/1853.0605.v83.n3.49438","url":null,"abstract":"Objetives: To describe a pediatric patient who developed acute disseminated encephalomyelitis (ADEM) during the acute phase of meningitis caused by Streptococcus pneumoniae, a previously unreported association.Case report: A previously healthy 3-year-old girl presented with fever and altered consciousness. She was diagnosed with bacterial meningoencephalitis and required mechanical ventilation. S. pneumoniae was isolated from blood and cerebrospinal fluid cultures. Despite clinical improvement after antibiotic therapy, persistent neurological deficits were observed. Brain MRI revealed lesions consistent with ADEM. She received corticosteroids and intravenous immunoglobulin with favorable clinical response and was discharged with outpatient follow-up and rehabilitation.Conclusion: This case highlights the need to consider ADEM as a differential diagnosis in children with persistent neurological symptoms during or after bacterial infections of the central nervous system. Early recognition and treatment can significantly improve outcomes.","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"83 3","pages":"e49438"},"PeriodicalIF":0.0,"publicationDate":"2026-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149081344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Subspinal osteotomy for mesiodens extraction. A technical note. 脊柱下截骨术中牙髓拔出术。一个技术说明。

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2026-08-06 DOI: 10.31053/1853.0605.v83.n3.49923

Carlos Marcelo Cerullo, Leonel Cristian Paladino, Julio César Carnicero, Karol Buchholz, Federico Garola

引用次数: 0

[Thrombus formation in the locking wire of a Nit Occlud PFO device. Advantage of the “reverse reconfiguration” of the left atrial disc] Nit-Occlud全氟辛烷磺酸装置释放系统中的隆起。左耳盘“反向重新配置”的优点。

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2026-08-05 DOI: 10.31053/1853.0605.v83.n3.49339

Alejandro Peirone, Alejandro Ernesto Contreras, Lautaro Molina, Alejo Contreras Bellotto, Marcelo Cabrera

引用次数: 0

[The demographic transition of the 21st Century93] 21世纪的人口转型。

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2026-08-04 DOI: 10.31053/1853.0605.v83.n3.53566

Eduardo Cuestas

引用次数: 0