María Virginia Zaragozá Zayas, Manuel Díaz del Río, Natalia Orozco Gil
{"title":"Manejo del ganglio intramamario metastásico en carcinoma de mama. Descripción de un caso","authors":"María Virginia Zaragozá Zayas, Manuel Díaz del Río, Natalia Orozco Gil","doi":"10.1016/j.senol.2024.100587","DOIUrl":"https://doi.org/10.1016/j.senol.2024.100587","url":null,"abstract":"<div><p>Patients diagnosed with breast carcinoma may sometimes present affected intramammary nodes. This fact influences the staging of tumors and, consequently, the treatment that will be provided. This article presents a clinical case on the management of a patient diagnosed with right breast neoplasia with an intramammary lymph node positive for metastasis. This posed a diagnostic challenge, since it required imaging techniques complementary to the usual ones and additional pathological studies. Regarding surgical management, a Grisotti technique, excision of the intramammary lymph node and selective biopsy of the sentinel lymph node were carried out. With this therapeutic approach, together with subsequent adjuvant treatment, it was possible to eradicate all the lesions known to date.</p></div>","PeriodicalId":38058,"journal":{"name":"Revista de Senologia y Patologia Mamaria","volume":"37 2","pages":"Article 100587"},"PeriodicalIF":0.0,"publicationDate":"2024-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140190871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Verónica Márquez Expósito , Dolors Del Hoyo Pastor , Èlia Sais Girona
{"title":"Descripción de un caso: carcinoma apocrino triple negativo de mama en el varón","authors":"Verónica Márquez Expósito , Dolors Del Hoyo Pastor , Èlia Sais Girona","doi":"10.1016/j.senol.2024.100586","DOIUrl":"https://doi.org/10.1016/j.senol.2024.100586","url":null,"abstract":"<div><p>Breast cancer in men is rare, accounting for less than 1% of all male cancers. It shares similarities with breast cancer in women, but also important differences. It occurs between 60 and 70 years with a peak age of 67 years. Invasive ductal carcinoma is the one that prevails in men, clinically it is detected as a painless unilateral nodule. Unlike women, where screening studies are carried out, men are usually diagnosed later, because they seek medical attention late due to the low incidence of cancer in male patients and the absence of early signs and symptoms. The diagnosis is usually clinical, but mammography can currently be used to differentiate between benign and malignant breast diseases. This article presents a clinical case of a man diagnosed with locally advanced triple-negative apocrine carcinoma of the breast.</p></div>","PeriodicalId":38058,"journal":{"name":"Revista de Senologia y Patologia Mamaria","volume":"37 2","pages":"Article 100586"},"PeriodicalIF":0.0,"publicationDate":"2024-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140164046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Linfoma B de la zona marginal extraganglionar de mama bilateral metacrónico","authors":"Lucía Isabel Martínez Minuesa, Sagrario Fuerte Ruiz, Teresa Carrascosa Mirón","doi":"10.1016/j.senol.2024.100585","DOIUrl":"https://doi.org/10.1016/j.senol.2024.100585","url":null,"abstract":"","PeriodicalId":38058,"journal":{"name":"Revista de Senologia y Patologia Mamaria","volume":"37 2","pages":"Article 100585"},"PeriodicalIF":0.0,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140145391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laia Bernet , Stella Peláez , Juan de la Camara de las Heras
{"title":"Patrón infrecuente de respuesta patológica a la terapia sistémica primaria","authors":"Laia Bernet , Stella Peláez , Juan de la Camara de las Heras","doi":"10.1016/j.senol.2024.100584","DOIUrl":"https://doi.org/10.1016/j.senol.2024.100584","url":null,"abstract":"<div><p>Neoadjuvant chemotherapy (NACT) has become the standard treatment for high-risk breast cancer. The pathological study of post-NACT surgical specimens, always complex and still insufficiently standardised, remains the gold standard for the definitive assessment of response, the morphological patterns of which must be identified. Pathologists, therefore, must identify NACT-induced changes in both tumour cells and tumour-associated stroma, as well as in the background breast tissue. Residual tumour volume after NACT is a significant prognostic factor and different methods have been proposed to quantify it. The most commonly used are the RCB and Miller-Payne systems. Although both indices are capable of stratifying response, the RCB has greater predictive power. Neither, however, provides information on certain poorly recognised morphological response patterns that, even without residual stromal tumour, should not be considered complete pathological response and their biological significance and prognostic value are controversial. We present a case of pure lymphovascular residual tumour response, morphological characterisation, and differential diagnosis, together with the applicability of the RCB and Miller-Payne indices in these cases.</p></div>","PeriodicalId":38058,"journal":{"name":"Revista de Senologia y Patologia Mamaria","volume":"37 2","pages":"Article 100584"},"PeriodicalIF":0.0,"publicationDate":"2024-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140062193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rebeca De la Iglesia López , Alejandra García-Novoa , Carmen Conde , Alberto Bouzón Alejandro , Benigno Acea-Nebril
{"title":"¿Es la disección axilar dirigida una alternativa en el carcinoma oculto de mama? Descripción de un caso","authors":"Rebeca De la Iglesia López , Alejandra García-Novoa , Carmen Conde , Alberto Bouzón Alejandro , Benigno Acea-Nebril","doi":"10.1016/j.senol.2024.100575","DOIUrl":"https://doi.org/10.1016/j.senol.2024.100575","url":null,"abstract":"<div><p>Occult breast carcinoma is a very rare entity that is defined as the presence of axillary disease without detectable tumor in the breast. When searching for the origin of a tumor, the use of bimodal techniques such as PET/CT has become especially useful, but there is little evidence about the management of these tumors. Currently, the standard treatment is primary systemic therapy (PST), followed by axillary lymphadenectomy and radiotherapy of the breast and lymph node chains. In this case we present the possibility of treating this disease with a more conservative surgical approach: through directed axillary dissection in a patient with occult breast carcinoma, who debuted with the appearance of a single axillary adenopathy observed on tomography. After completing primary systemic therapy, a complete radiological response was confirmed and a directed axillary dissection was indicated, with evidence in the operating room of a coincidence between the sentinel lymph node and the lymph node initially biopsied. After completing the treatment with radiotherapy of the breast and lymph node chains and anti-Her2 therapy, the patient is disease-free. It seems that an axillary treatment similar to that of locally advanced breast cancer can be considered, so in limited axillary disease (N1) targeted axillary dissection associated with radiotherapy could be an alternative.</p></div>","PeriodicalId":38058,"journal":{"name":"Revista de Senologia y Patologia Mamaria","volume":"37 2","pages":"Article 100575"},"PeriodicalIF":0.0,"publicationDate":"2024-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139718428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Utilización de semillas magnéticas en la cirugía de la mama y la axila: revisión de la literatura","authors":"Sagrario Fuerte Ruiz","doi":"10.1016/j.senol.2024.100574","DOIUrl":"https://doi.org/10.1016/j.senol.2024.100574","url":null,"abstract":"<div><p>The raise of non-palpable breast and axillary lesions has led to the development of multiple diagnostic techniques. Each one with its own has advantages and limitations. Currently, the technique using magnetic seed has increased, leading to a decrease of the other one. The aim of this study is to assess the recent experience of different groups and analyse the arguments in favour of using magnetic seed as a diagnostic technique for non-palpable breast and axillary lesions.</p><p>A literature review has been performed on PubMed and EMBASE, including articles in English and Spanish from 2018 to 2022. No restrictions have been made regarding the type of study. Forty-three articles were selected, with contributions and experiences in different countries.</p></div>","PeriodicalId":38058,"journal":{"name":"Revista de Senologia y Patologia Mamaria","volume":"37 2","pages":"Article 100574"},"PeriodicalIF":0.0,"publicationDate":"2024-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139675772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eugenia Morillo, Manuel Sánchez-Prieto, Sandra García, Sonia Baulies, Rafael Fàbregas, Carmen Ara, Francesc Tresserra
{"title":"Técnica de la biopsia selectiva del ganglio centinela en tumores multifocales de la mama","authors":"Eugenia Morillo, Manuel Sánchez-Prieto, Sandra García, Sonia Baulies, Rafael Fàbregas, Carmen Ara, Francesc Tresserra","doi":"10.1016/j.senol.2024.100573","DOIUrl":"https://doi.org/10.1016/j.senol.2024.100573","url":null,"abstract":"<div><h3>Introduction</h3><p>Multifocal (MF) breast cancer challenges the diagnostic strategy due to the controversy about selective sentinel node biopsy (SSNB) in these cases. The aim was to evaluate the feasibility of SSNB and associated tumor characteristics in patients with MF breast cancer.</p></div><div><h3>Material and methods</h3><p>A longitudinal retrospective study of patients diagnosed with MF carcinoma between 1999 and 2022 was performed. A total of 254 cases were included, of which SSNB was performed in 124. Relevant clinical and tumor variables were analyzed using data from anonymized medical records and corresponding ethical approval.</p></div><div><h3>Results</h3><p>The mean age of the patients was 53.9 ± 11.6 years. The predominant histological type was ductal (71.8%). The mean size of the major focus was 14.8 ± 9.5. SSNB showed negative results in most cases (70.9%), while in others isolated tumor cells (0.8%), micrometastases (6.5%), and macrometastases (21.8%) were detected. Prevalence of estrogen receptor-positive (94.4%), progesterone-positive (82.3%), and HER2-negative (62.9%) tumors was observed.</p></div><div><h3>Conclusion</h3><p>SSNB in MF tumors was performed in most cases in which multifocality did not contraindicate the technique. In those cases where SSNB was performed, ductal carcinomas were predominant, same as hormone receptor positive and HER2 negative carcinomas.</p></div>","PeriodicalId":38058,"journal":{"name":"Revista de Senologia y Patologia Mamaria","volume":"37 2","pages":"Article 100573"},"PeriodicalIF":0.0,"publicationDate":"2024-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139653740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrés García-Vilanova Comas , María Castillo Antón , Alejandra De Andrés Gómez , Verónica Gumbau Puchol , Carlos Castañer Puga , María José García Coret , Francisco Javier Tarrasa Peiró , Cristóbal Zaragozá Fernández
{"title":"Correlación clínico-patológica para el diagnóstico de mastitis crónica tratada con cirugía","authors":"Andrés García-Vilanova Comas , María Castillo Antón , Alejandra De Andrés Gómez , Verónica Gumbau Puchol , Carlos Castañer Puga , María José García Coret , Francisco Javier Tarrasa Peiró , Cristóbal Zaragozá Fernández","doi":"10.1016/j.senol.2023.100564","DOIUrl":"https://doi.org/10.1016/j.senol.2023.100564","url":null,"abstract":"<div><h3>Objectives</h3><p>Chronic mastitis (CM) frequently relapse without an identified etiology, although they have been treated with a spectrum of treatments that includes different antibiotics, anti-inflammatories and surgery, more or less aggressive depending on their extension. The objective is to investigate if clinicopathological correlation is useful in the diagnosis of CM.</p></div><div><h3>Material and methods</h3><p>A descriptive, observational and retrospective study of a series of 100 patients (n = 100) diagnosed during ten years with CM is presented. Anamnesis, clinical debut, physical examination, imaging techniques, type of surgery, number of recurrences, histological inflammatory pattern data, complementary tests including microbiological study and serology, number of biopsies, number of consultation visits and time until final diagnosis are evaluated. Finally, the average of cases diagnosed by clinicopathological correlation is determined.</p></div><div><h3>Results</h3><p>Results of surgical interventions, clinical and histopathological findings, microbiology and serology are included in tables. Clinicopathological correlation achieved etiopathogenic diagnosis in 99% of the cases including chronic suppurative galactophoritis (91%); vasculitis (3%), two of them compatible with granulomatosis with polyangiitis; idiopathic granulomatous mastitis (2%) and non-diabetic lymphocytic lobulillitis (3%). Thirty-eight percent of the cases presented recurrences. The mean time to definitive diagnosis was 20.02 (standard deviation = 49.87) weeks. The average number of visits to outpatient clinics was 15.35 (standard deviation = 14.97).</p></div><div><h3>Conclusions</h3><p>Clinicopathological correlation improves the diagnosis of CM, specially relapsed and without an identified etiology, although it may take a long time.</p></div>","PeriodicalId":38058,"journal":{"name":"Revista de Senologia y Patologia Mamaria","volume":"37 2","pages":"Article 100564"},"PeriodicalIF":0.0,"publicationDate":"2024-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139399167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sonar Soni Panigoro , Arga Patrianagara , Ninik Sukartini , Trevino Aristarkus Pakasi , Samuel Johny Haryono
{"title":"Inflammatory indicators as a prognostic factor of clinical response in locally advanced breast cancer (LABC) patients receiving neoadjuvant chemotherapy (NAC)","authors":"Sonar Soni Panigoro , Arga Patrianagara , Ninik Sukartini , Trevino Aristarkus Pakasi , Samuel Johny Haryono","doi":"10.1016/j.senol.2023.100553","DOIUrl":"https://doi.org/10.1016/j.senol.2023.100553","url":null,"abstract":"<div><h3>Objectives</h3><p><span><span>Breast cancer is a prevalent and fatal cancer worldwide. Neoadjuvant chemotherapy<span> is a treatment option used to reduce tumor size </span></span>in patients with </span>locally advanced breast cancer<span>. The neutrophil–lymphocyte ratio (NLR), lymphocyte–monocyte ratio (LMR), and platelet–lymphocyte ratio (PLR) are inflammatory markers that have been studied as prognostic factors in breast cancer. This cross-sectional study aimed to investigate the role of NLR, LMR, and PLR in the clinical response to neoadjuvant chemotherapy in women with locally advanced breast cancer.</span></p></div><div><h3>Materials and methods</h3><p>We used a cross-sectional research design for this study with the aim of observing the relation between NLR, LMR, and PLR and the clinical response of neoadjuvant chemotherapy. The study was conducted in Cipto Mangunkusumo General Hospital. We analyzed the medical records of 84 patients treated with neoadjuvant chemotherapy between 2016 and 2021.</p></div><div><h3>Results</h3><p><span>Our study found that majority of the subjects receives CAF combination of NAC with inoperable breast cancer. Most of the subjects have luminal B type of breast cancer and no clinical response to chemotherapy regimen. Surgery has significant association with clinical response in patients receiving NAC (</span><em>P</em> = <.001). There are no significant correlation between NLR, LMR, and PLR with clinical response to neoadjuvant chemotherapy. However, we did observe a significant association between NLR and 1-year mortality rate.</p></div><div><h3>Conclusion</h3><p>In conclusion, significant association between NLR and 1-year morality rate suggest that NLR may serve as a useful prognostic factor in breast cancer patients receiving neoadjuvant chemotherapy.</p></div>","PeriodicalId":38058,"journal":{"name":"Revista de Senologia y Patologia Mamaria","volume":"37 1","pages":"Article 100553"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139090112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
David Martinez-Ramos , Antonio Piñero-Madrona , Francesc Tresserra-Casas , Eduardo Alcobilla-Ferrara , Manel Algara-López
{"title":"Impact factor achieved (But this is just the beginning)","authors":"David Martinez-Ramos , Antonio Piñero-Madrona , Francesc Tresserra-Casas , Eduardo Alcobilla-Ferrara , Manel Algara-López","doi":"10.1016/j.senol.2023.100561","DOIUrl":"https://doi.org/10.1016/j.senol.2023.100561","url":null,"abstract":"","PeriodicalId":38058,"journal":{"name":"Revista de Senologia y Patologia Mamaria","volume":"37 1","pages":"Article 100561"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139090164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}