Journal of Mid-life Health最新文献

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Proportion, Pattern, and Predictors of Falls in Older Adults – A Community-based Observational Study in Rural West Bengal 老年人跌倒的比例、模式和预测因素——西孟加拉邦农村一项基于社区的观察研究
Journal of Mid-life Health Pub Date : 2023-01-01 DOI: 10.4103/jmh.jmh_35_23
Dipankar Jana, Monalisha Sahu, Bobby Paul, Sandipta Chakraborty, Lina Bandyopadhyay, Ranjan Das
{"title":"Proportion, Pattern, and Predictors of Falls in Older Adults – A Community-based Observational Study in Rural West Bengal","authors":"Dipankar Jana, Monalisha Sahu, Bobby Paul, Sandipta Chakraborty, Lina Bandyopadhyay, Ranjan Das","doi":"10.4103/jmh.jmh_35_23","DOIUrl":"https://doi.org/10.4103/jmh.jmh_35_23","url":null,"abstract":"Introduction: In spite of falls being a major public health problem, where most of the falls are preventable, there is a lack of epidemiological investigation among those aged 50 and above, especially in developing countries. Hence, we investigate the proportion, pattern, and predictors of falls in this age group. Materials and Methods: This cross-sectional community-based study was done in the Uluberia-II block of Howrah district, West Bengal, from February to July 2021. A multistage cluster sampling method was used to meet the sample size. Data were collected with the help of a structured interview schedule. Predictors were estimated by the SPSS version 16 and defined in adjusted odds ratio (AOR) with a 95% confidence interval. Results: Among 170 study participants, 34.7% (59/170) experienced at least one episode of fall, while 20.6% (35/170) experienced recurrent falls in 12 months. Most (78%; 46/59) falls occurred in the home environment and due to slippage (67.8%; 40/59) on the floor. 84.7% (50/59) sustained any type of injuries, 47.5% (28/59) required either consultation of a physician or medication, and 6.8% (4/59) required hospitalization. Safety Checklist Score measured 75.3% (128/170) had a poor household environment, within that 30.6% (52/170) had a seriously poor household environment, which was an important predictor of falls ([AOR] = 3.59 [1.24–10.38]). Fear of fall (AOR = 6.18 [1.77–21.53]) measured by shortfall efficacy scale and nonformal education (AOR = 5.05 [1.33–19.07]) were also predictors of falls. Conclusion: Considerable proportion of falls occurred in the past year, which can be preventable by improving modifiable environmental factors and detection of fear of fall in persons at different levels of health-care facilities.","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135550654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of Oral Cancer in Western Population of Maharashtra for 3 Years: A Prospective Study. 3年来马哈拉施特拉邦西部人群口腔癌症患病率的前瞻性研究。
IF 1.1
Journal of Mid-life Health Pub Date : 2023-01-01 Epub Date: 2023-07-07 DOI: 10.4103/jmh.jmh_44_23
Abhishek Anilrao Gole, S R Ashwinirani, Vidya Kadashetti, Girish Suragimath, Shrutika Muneshwar, Priti Godse
{"title":"Prevalence of Oral Cancer in Western Population of Maharashtra for 3 Years: A Prospective Study.","authors":"Abhishek Anilrao Gole,&nbsp;S R Ashwinirani,&nbsp;Vidya Kadashetti,&nbsp;Girish Suragimath,&nbsp;Shrutika Muneshwar,&nbsp;Priti Godse","doi":"10.4103/jmh.jmh_44_23","DOIUrl":"10.4103/jmh.jmh_44_23","url":null,"abstract":"<p><strong>Introduction: </strong>In developing countries, oral cancer (OC) is estimated to be the third most common malignancy after cancer of the cervix and stomach. The aim of this study was to report the prevalence of OC for 3 years and its association with age, gender, type, and duration of habits along with the site of OC.</p><p><strong>Materials and methods: </strong>This study was conducted in the Department of Oral Medicine and Radiology from January 2019 to December 2021. All the patients were examined after recording their demographic data using a mouth mirror and probe. The diagnosis of OC was arrived based on the clinical features of the lesions. The type and duration of habits and site were recorded in clinical pro forma. The Statistical Package for the Social Sciences (SPSS) software version 21.0 was used for the statistical analysis, the Chi-square test was applied, and the significance level was set at <i>P</i> < 0.05.</p><p><strong>Results: </strong>The prevalence of OC was 0.22% in our study. Of 317 cases, the majority of the patients were males (<i>n</i> = 204), and females (<i>n</i> = 113) accounted for a male: female ratio of 2:1. The most common age affected was 51-70 years with a history of tobacco chewing, followed by patients with multiple habits (smokers, tobacco chewers, and alcoholic). The buccal mucosa was the most common site followed by malignancies of multiple sites.</p><p><strong>Conclusion: </strong>Regular camps regarding tobacco cessation and counseling should be taken care of by dentists. Male patients aged above 40 years are routinely recommended for dental visits.</p>","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/1e/f7/JMH-14-3.PMC10482017.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10189126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Expression of Programmed Cell Death Ligand-1 and Mismatch Repair Status in Endometrial Carcinomas 子宫内膜癌中程序性细胞死亡配体-1的表达和错配修复状态
Journal of Mid-life Health Pub Date : 2023-01-01 DOI: 10.4103/jmh.jmh_6_23
Madhubala Rajendran, Meenakshi Rao, Poonam Abhay Elhence, Jyotsna Naresh Bharti, Pratibha Singh, Garima Yadav, Aasma Nalwa, Akhil Dhanesh Goyal
{"title":"Expression of Programmed Cell Death Ligand-1 and Mismatch Repair Status in Endometrial Carcinomas","authors":"Madhubala Rajendran, Meenakshi Rao, Poonam Abhay Elhence, Jyotsna Naresh Bharti, Pratibha Singh, Garima Yadav, Aasma Nalwa, Akhil Dhanesh Goyal","doi":"10.4103/jmh.jmh_6_23","DOIUrl":"https://doi.org/10.4103/jmh.jmh_6_23","url":null,"abstract":"Background and Aims: Programmed death ligand-1 (PD-L1) is a co-regulatory molecule that suppresses local immunity, and mismatch repair (MMR) deficiency (dMMR) is reported to influence the response to anti-PD-L1-targeted therapy. This study was conducted to find the PD-L1 status, the occurrence of dMMR in endometrial carcinomas, and the association between them. Materials and Methods: The study included 35 resected specimens of endometrial carcinomas represented on formalin-fixed paraffin-embedded sections from January 2016 to July 2020. The clinicopathologic information including patient age, tumor histologic type, grade, stage, lymphovascular invasion, the extent of myometrial invasion, and the percentage of tumor-infiltrating lymphocytes (TILs) were obtained in all cases. The expression of PD-L1 and MMR antibodies including mutS homolog 2 (MSH-2), MSH-6, mutL homolog 1 (MLH-1) and MLH-3, and postmeiotic segregation 2 were assessed using immunohistochemistry. The statistical analysis was done using the Statistical Package for the Social Sciences (SPSS) version 26. Results: PD-L1 expression was noted in 48.6% of the cases in tumor cells and 65.7% of the cases in TILs and MMR was deficient in 28.6% of endometrial carcinomas. A statistically significant relation was noted between dMMR and TILs, PD-L1 expression in tumor cells and TILs, PD-L1 expression in tumor cells, and extent of myometrial invasion. Although there was no statistically significant association between MMR status and PD-L1 expression in tumor cells or TILs, 60% of patients with dMMR were PD-L1 positive. Conclusion: Sixty percent of dMMR cases showed PD-L1 expression in tumor cells. We conclude, ECs that are MMR deficient might get better response to anti-PD-L1 therapy. This study also revealed the prognostic use of TILs in PD-L1-expressed tumors.","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135550472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
To Study the Efficacy and Safety of Diosmin with Tranexamic Acid and Mefenamic Acid Versus only Tranexamic Acid and Mefenamic Acid in Medical Management of Abnormal Uterine Bleeding: A Randomized Controlled Trial 研究地奥明联合氨甲环酸和甲芬那酸与仅氨甲环酸和甲芬那酸治疗子宫异常出血的疗效和安全性:一项随机对照试验
Journal of Mid-life Health Pub Date : 2023-01-01 DOI: 10.4103/jmh.jmh_253_22
J. B. Sharma, Rajesh Kumari, Supriya Kumari, Shubhangi Jain, Sona Dharmendra
{"title":"To Study the Efficacy and Safety of Diosmin with Tranexamic Acid and Mefenamic Acid Versus only Tranexamic Acid and Mefenamic Acid in Medical Management of Abnormal Uterine Bleeding: A Randomized Controlled Trial","authors":"J. B. Sharma, Rajesh Kumari, Supriya Kumari, Shubhangi Jain, Sona Dharmendra","doi":"10.4103/jmh.jmh_253_22","DOIUrl":"https://doi.org/10.4103/jmh.jmh_253_22","url":null,"abstract":"Background: Abnormal uterine bleeding (AUB) is a common problem in reproductive age group and perimenopausal age group being responsible for many outpatient visits. Traditional management of AUB consists of giving mefenamic acid, tranexamic acid, or their combination with progestogens or hormonal intrauterine deviced levonorgestrel intrauterine system (LNG-IUS) for severe or nonresponsive cases. The objective of the current study was to study the efficacy and safety of adding diosmin along with tranexamic acid and mefenamic acid in reducing menstrual blood loss in AUB patients. Materials and Methods: It was a prospective double-blind randomized controlled trial in which 900 mg of diosmin was given once daily along with 500 mg tranexamic acid and 250 mg mefenamic acid during menstruation (Group I-92 patients), or only tranexamic acid and mefenamic acid during menstruation (Group II-92 patients). Results: Mean age, parity, body mass index, and socioeconomic status were similar in the two groups. It was 35.68 years versus 36.78 years, 2.2 versus 2.3, 23.68 kg/m 2 versus 24.62 kg/m 2 respectively. Mean days of bleeding before this treatment were 6.8 versus 6.6 ( P = 0.33) and were 3.5 versus 5.2 ( P = 0.02) after treatment. There was a significant reduction in both groups as compared to before treatment ( P = 0.021 in Group I, 0.027 in Group II) but the reduction was greater in Group I ( P = 0.02). The amount of blood loss was 385 ml versus 390 ml ( P = 0.7) before treatment which was significantly reduced in both groups to 68 ml versus 112 ml ( P = 0.02 in Group I, 0.03 in Group II) with more decrease in Group I than in Group II ( P = 0.01). Mean hemoglobin at beginning of the study was 8.4 versus 8.5 g/dl in Group I and Group II ( P = 0.02) and significantly increased in both groups posttreatment to 10.9 and 9.8 g/dl in Group I and Group II ( P = 0.012 in Group I, 0.011 in Group II) with increase being more in Group I than Group II ( P = 0.03). Pictorial blood assessment chart score was 398 versus 406 ( P = 0.35) before treatment and decreased significantly to 86.5 and 110.5 ( P = 0.001 in Group I, 0.001 in Group II) with more decrease being in Group I than II ( P = 0.01). There was significant decrease in dysmenorrhea with both treatments with no difference in the two groups. Various adverse effects such as nausea, vomiting, abdominal pain, diarrhea, constipation, and headache were equal in the two groups. Conclusion: Both the group’s diosmin with tranexamic acid and mefenamic acid (Group I) and tranexamic acid and mefenamic acid (Group II) were efficacious in reducing menstrual blood loss, number of menstrual days and dysmenorrhea with effect being more by addition of diosmin. Adverse effects were equal in both the two groups.","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135550179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Skin Metastases in Ovarian Malignancy: A Case Report with Literature Review. 卵巢恶性肿瘤的皮肤转移:一例报告并文献复习。
IF 1.1
Journal of Mid-life Health Pub Date : 2023-01-01 Epub Date: 2023-07-07 DOI: 10.4103/jmh.jmh_137_22
Vibha Rani Pipal, Pratibha Singh, Dharmendra Kumar Pipal, Poonam Elhence
{"title":"Skin Metastases in Ovarian Malignancy: A Case Report with Literature Review.","authors":"Vibha Rani Pipal,&nbsp;Pratibha Singh,&nbsp;Dharmendra Kumar Pipal,&nbsp;Poonam Elhence","doi":"10.4103/jmh.jmh_137_22","DOIUrl":"10.4103/jmh.jmh_137_22","url":null,"abstract":"<p><p>Ovarian cancer is the most lethal gynecologic malignancy, mostly diagnosed in the advanced stage with multiple sites of metastases. Routes of spread are direct through exfoliation, lymphatic channels, and less commonly hematogenous spread. Skin metastasis in ovarian malignancy is a rare occurence, its incidence range from 1.9% to 5.1% and the most common sites are the abdominal wall and chest wall. The incidence of metastasis to breast and/or axillary lymph nodes is very rare, ranging from 0.03% to 0.6%. We report the case of a 60-year-old female with stage IV B undifferentiated ovarian carcinoma with multiple cutaneous metastases involving the skin over the left breast, scalp, and mediastinal lymph nodes, which are rare sites of metastases. The incidence of cutaneous metastasis in ovarian cancer is 1.9%-5.1% and the overall survival after diagnosis ranges from 2 to 65 months.</p>","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4e/89/JMH-14-49.PMC10482014.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10180034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synchronous Occurrence of Adult Granulosa Cell Tumor with Fibroma in One Ovary and Brenner Tumor in Other Ovary: An Extremely Unusual Case. 一个卵巢同时发生成人颗粒细胞肿瘤伴纤维瘤,另一个卵巢并发Brenner肿瘤:一例极不寻常病例。
IF 1.1
Journal of Mid-life Health Pub Date : 2023-01-01 Epub Date: 2023-07-07 DOI: 10.4103/jmh.jmh_26_22
Alka Yadav, Mukta Pujani, Kanika Singh, Varsha Chauhan, Aparna Singh, Jagadish Chandra Sharma
{"title":"Synchronous Occurrence of Adult Granulosa Cell Tumor with Fibroma in One Ovary and Brenner Tumor in Other Ovary: An Extremely Unusual Case.","authors":"Alka Yadav,&nbsp;Mukta Pujani,&nbsp;Kanika Singh,&nbsp;Varsha Chauhan,&nbsp;Aparna Singh,&nbsp;Jagadish Chandra Sharma","doi":"10.4103/jmh.jmh_26_22","DOIUrl":"10.4103/jmh.jmh_26_22","url":null,"abstract":"<p><p>Ovarian tumors are a common form of neoplasia in women and it accounts for about 30% of female genital cancers. A coexistence of ovarian tumors with the same histogenetic origin such as germ cell or epithelial or sex cord stromal, but different histologic subtype is relatively common, whereas a synchronous occurrence of tumors with different histogenetic origin is rare. We report a case of 58-year-old woman with the synchronous presentation of adult granulosa cell tumor with fibroma (ovarian tumors with the same origin (sex cord stromal) but different histologic type) in one ovary and Brenner tumor (epithelial origin) in other ovary. Our patient presented with postmenopausal bleeding and was diagnosed with this rare combination of ovarian tumors on histopathology supplemented with immunohistochemistry. On extensive literary search, there is only a single report of mixed ovarian tumor composed of Brenner tumor and adult-type granulosa cell tumor. Our case is different from the above-mentioned report as although, in our patient both tumors coexisted, but in contralateral ovaries.</p>","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/95/46/JMH-14-56.PMC10482026.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10187663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oral Manifestation in Postmenopausal Women of Maharashtra, Western Region. 马哈拉施特拉邦西部地区绝经后妇女的口腔表现。
IF 1.1
Journal of Mid-life Health Pub Date : 2023-01-01 Epub Date: 2023-07-07 DOI: 10.4103/jmh.jmh_194_22
Shrutika Sanjay Muneshwar, S R Ashwinirani, Abhishek Anilrao Gole, Girish Suragimath
{"title":"Oral Manifestation in Postmenopausal Women of Maharashtra, Western Region.","authors":"Shrutika Sanjay Muneshwar,&nbsp;S R Ashwinirani,&nbsp;Abhishek Anilrao Gole,&nbsp;Girish Suragimath","doi":"10.4103/jmh.jmh_194_22","DOIUrl":"10.4103/jmh.jmh_194_22","url":null,"abstract":"<p><strong>Introduction: </strong>Menopause in women is a physiological state that gives rise to adaptive changes at both the systemic and oral levels. The oral manifestations of postmenopausal women may vary for each patient. It occurs in the form of burning mouth syndrome, xerostomia, periodontitis, etc., We aimed to assess the prevalence of oral manifestations in the postmenopausal population, to know the nature and severity of oral manifestations occurring in postmenopausal women, and to assess the systemic conditions of these postmenopausal women with oral manifestations. The study was designed to assess the oral manifestation in postmenopausal women of Maharashtra, Western region.</p><p><strong>Materials and methods: </strong>The study was conducted in the department of oral medicine and radiology. A total of 90 patients were included. A detailed clinical examination was done using a mouth mirror and probe. The clinical pro forma recorded demographic data, including the duration of menopause and different oral manifestations like xerostomia, periodontitis, lichen planus, oral candidiasis, etc., Collected data were entered into MS Excel and subjected to statistical analysis.</p><p><strong>Results: </strong>In the study, there were a total of 90 patients. These patients were distributed into three groups based on their age groups. The majority of the oral manifestations were reported in patients belonging to Group 2 (60-70 years age group).</p><p><strong>Conclusion: </strong>Overall, 76.6% of patients reported oral mucosal changes; of which 20.2% of patients reported xerostomia, 15.9% reported periodontitis, 13% showed altered taste, 8.6% of patients had lichen planus, and 7.2% patients reported oral candidiasis and space infections.</p>","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/84/4a/JMH-14-28.PMC10482020.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10559780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Integrating Technologies: An Affordable Health Care System in Digital India 整合技术:数字印度负担得起的医疗保健系统
Journal of Mid-life Health Pub Date : 2023-01-01 DOI: 10.4103/jmh.jmh_138_23
Maninder Ahuja, Avir Sarkar, Vartika Sharma
{"title":"Integrating Technologies: An Affordable Health Care System in Digital India","authors":"Maninder Ahuja, Avir Sarkar, Vartika Sharma","doi":"10.4103/jmh.jmh_138_23","DOIUrl":"https://doi.org/10.4103/jmh.jmh_138_23","url":null,"abstract":"India is a country with 1.428 billion population making 17.76% of world’s population.[1] Added to that, our challenges are diversity and heterogeneity of culture, tradition, diets, and religion. Hence, a strong, organized, and efficient health-care system is of paramount importance to the country’s economic well-being. Health care is a humongous ever-flourishing industry in India. As technology, diagnostics and therapeutics are evolving so are the increased challenges of prevention and reaching out to marginalized groups with administration of treatment and after-care services. Health care is a broad-spectrum speciality ranging from intricate diagnostics such as imaging and therapeutics on the one end to basic mobile van camp services on the other. Accessibility and affordability to health care also varies significantly among urban and rural population, with marginalized communities being almost deprived from these services. Integrated health-care ecosystem is a need of the era and demands a systematic and comprehensive approach addressing its different aspects including heightened health awareness, thus strengthening preventive medicine, focusing on primary health-care domains, developing health-care infrastructure and involving private sectors, etc. Digitization comes as a boon in adversity. New-age technologies such as artificial intelligence (AI), robotics, and internet of things (IoT) are ever welcoming for further advancement of health-care sector in digital India. In the words of John McCarthy, “Artificial intelligence is science and engineering of making intelligent machines especially intelligent computer program.”[2] Applications of AI in health care are a topic worthy of one separate discussion owing to its tremendous possibilities in modern Indian health care. It can take care of large amount of health sector data and provide significant inferences within seconds. Various AI-powered health applications can help in speedy disease detection and treatment. AI can predict various health trends, thus helping in efficient allocation of health resources and compression of morbidities. As an obstetrician, AI is useful in multiple aspects of obstetric care including both diagnostics and therapeutics.[3] For example, computerized fetal cardiotocography can detect abnormal records well in time, resulting in timely intervention and improved maternal and fetal outcome as shown by Alfirevic et al.[4] Various AI-based risk prediction calculators for preeclampsia and aneuploidies help in appropriate counseling and management of many mothers-to-be. The International Society of Ultrasound in Obstetrics and Gynecology (ISUOG) held a special session in 2020, they stated that AI-based software automatically detects the best spatial planes and soon will provide diagnosis alongside measurements.[5] AI plays a vital role in gynecological care as well. Various cervical cancer screening methods including Papanicolaou smear, visual inspection under acetic acid,","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135549951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Histomorphological Evaluation of Desmoplastic Tumor Stroma in Malignant Ovarian Surface Epithelial Tumors 恶性卵巢表面上皮性肿瘤间质间质组织形态学评价
Journal of Mid-life Health Pub Date : 2023-01-01 DOI: 10.4103/jmh.jmh_31_23
Sana Ahuja, Sufian Zaheer, Sunil Ranga
{"title":"Histomorphological Evaluation of Desmoplastic Tumor Stroma in Malignant Ovarian Surface Epithelial Tumors","authors":"Sana Ahuja, Sufian Zaheer, Sunil Ranga","doi":"10.4103/jmh.jmh_31_23","DOIUrl":"https://doi.org/10.4103/jmh.jmh_31_23","url":null,"abstract":"Background: Ovarian cancer is the 8th most common cancer in women worldwide. Tumor budding is defined as a type of invasive growth in carcinomas with either a single tumor cell or a cluster of up to four cells at the invasive tumor front and is associated with epithelial–mesenchymal transition. A reactive stroma rich in cancer-associated fibroblasts is associated with higher tumor grade and poorer prognosis in breast, colorectal, and oral cancers. Aims and Objectives: The present study was conducted to highlight the prognostic significance of tumor budding and fibrotic cancer stroma in malignant ovarian surface epithelial tumors with known prognostic parameters. Materials and Methods: This was a retrospective cross-sectional study conducted over a 2-year period, in which all histologically diagnosed cases of malignant ovarian surface epithelial tumors who underwent surgery were included. The fibrotic stroma was classified into three distinct categories – mature, intermediate, and immature. The number of tumor buds was counted at the invasive front of the tumor and graded based on the number of buds – 0–5, 5–9, and ≥10 buds. Results: Among the 50 cases, 32% (16 cases) had mature stroma, whereas 30% (15 cases) and 38% (19 cases) had intermediate and immature stroma, respectively. Although a significant association could not be established between tumor budding and stroma grade, a fair agreement was established between them. A significant association could be established between histological grade with both tumor budding (P = 0.03) and fibrotic stroma grade (P = 0.02). Conclusion: The study highlighted the role of stromal response in malignant surface epithelial tumors of the ovary since a higher-grade tumor was associated with an immature stroma, whereas a lower-grade tumor was associated with a mature stroma.","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135550467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unilateral Ectopic Breast Tissue in the Vulva - A Diagnostic Dilemma. 外阴单侧异位乳房组织——诊断难题。
IF 1.1
Journal of Mid-life Health Pub Date : 2023-01-01 Epub Date: 2023-07-07 DOI: 10.4103/jmh.jmh_209_22
Dashora Sanchita, Joshi Ruchi
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