Journal of Mid-life Health最新文献

{"title":"Device-free, Cost-effective Sacrospinous Fixation Using Absorbable versus Nonabsorbable Sutures: A 5-Year Prospective, Cohort Study.","authors":"Ruchika Garg, Neelansha Varshney","doi":"10.4103/jmh.jmh_64_26","DOIUrl":"10.4103/jmh.jmh_64_26","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the efficacy and safety of device-free concurrent sacrospinous fixation (SSF) performed at the time of vaginal hysterectomy using absorbable (polyglactin no. 1) versus nonabsorbable (polypropylene no. 1) sutures for preventing vaginal vault prolapse.</p><p><strong>Materials and methods: </strong>A prospective, comparative, cohort study included 185 women undergoing vaginal hysterectomy for pelvic organ prolapse (POP) stages II-IV from January 2016 to December 2018. Prophylactic SSF was performed in 90 patients using Polyglactin No. 1 sutures while in 95 patients using nonabsorbable sutures (Polypropylene No. 1). In both groups, Garg's technique was performed using Allis tissue forceps rather than a Capio device. Absorbable sutures (<i>n</i> = 90) were passed through the full thickness from sacrospinous ligament and tied to the vault while nonabsorbable sutures (<i>n</i> = 95) were placed submucosally in a double helix pattern and tied beneath the mucosa. The outcomes included anatomical success (POP-Q stage < II), recurrence rates, complications, and quality of life. Follow-up occurred at 1 month, 6 months, and annually for 5 years.</p><p><strong>Results: </strong>Anatomical success was achieved in 89/90 (98.9%) patients till 5 years with absorbable sutures, with a vault prolapse recurrence rate of 1.1% (1/90) versus 4.2% (4/95) with nonabsorbable sutures (<i>P</i> = 0.37). The complications included fever (1.1%) and urinary tract infection (UTI) (3.3%). No suture exposure or granuloma formation occurred with absorbable sutures, unlike 2.1% with nonabsorbable sutures (<i>P</i> = 0.50). Garg's technique reduced the cost by avoiding Capio device.</p><p><strong>Conclusion: </strong>Concurrent sacrospinous fixation using Polyglactin no. 1 sutures with a simplified device-free technique demonstrated high long-term anatomical success rate and lower complication rates comparable to nonabsorbable sutures. This approach may be particularly useful in the resource-constrained settings.</p>","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":"17 2","pages":"248-252"},"PeriodicalIF":1.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13460698/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148713848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bladder Endometriosis: A Rare Histopathological Entity Diagnosed by Transurethral Resection.","authors":"Shabana Andleeb Ansari, Mohd Mubashir Ali Khan, Geeta Maurya, Manzeela Swale, Beant Kaur, Neha Yadav, Priyanka Mishra","doi":"10.4103/jmh.jmh_348_25","DOIUrl":"10.4103/jmh.jmh_348_25","url":null,"abstract":"<p><p>Bladder endometriosis is a rare form of deep infiltrating endometriosis involving the urinary tract, often presenting with nonspecific urinary or pelvic symptoms and mimicking neoplastic conditions. This report describes a 28-year-old nulliparous female who presented with recurrent pelvic discomfort. Imaging revealed a bladder wall lesion near the vesicoureteric junction, prompting transurethral resection. Histopathological examination facilitated the proper diagnosis. The case highlights the need for a comprehensive diagnostic approach in atypical cases of bladder pathology.</p>","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":"17 2","pages":"309-311"},"PeriodicalIF":1.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13460699/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148713786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral Changes and the Role of Hygiene in Peri- and Postmenopausal Women - A Comparative Study.","authors":"Tapasya Karemore, Shiwani Dalal, Mukta Motwani, Apeksha Dhole, Smriti Golhar, Rucha Pandhripande","doi":"10.4103/jmh.jmh_183_25","DOIUrl":"10.4103/jmh.jmh_183_25","url":null,"abstract":"<p><strong>Background: </strong>Menopause is a transitional phase involving significant hormonal changes that influence the oral cavity. Oral manifestations such as hyposalivation, xerostomia, periodontal disease, mucosal changes, burning mouth syndrome, and altered taste are frequently observed. However, the role of oral hygiene during this stage is often underemphasized.</p><p><strong>Aim: </strong>To assess oral changes and the role of oral hygiene in women across pre-, peri-, and postmenopausal stages, and to explore their secondary impact on systemic and psychological well-being.</p><p><strong>Materials and methods: </strong>A cross-sectional study was conducted on 60 women (20 in each menopausal stage). Oral parameters evaluated included salivary flow and pH, periodontal indices, taste perception, and mucosal changes. Data were analyzed using Spearman's correlation and Kruskal-Wallis tests.</p><p><strong>Results: </strong>Salivary flow and pH declined significantly from pre- to postmenopausal groups. Higher prevalence of xerostomia, burning mouth, impaired taste perception, and periodontal breakdown were noted in peri- and postmenopausal women. Poorer oral health indices were associated with reduced hygiene practices and showed correlations with systemic parameters (lipids, blood pressure, and glucose) and psychological distress scores.</p><p><strong>Conclusion: </strong>Menopausal transition has a pronounced effect on oral health and hygiene maintenance. Neglected oral conditions may secondarily worsen systemic risk factors and psychological well-being. Emphasis on preventive oral care and routine dental screening should form an essential part of menopausal health programs.</p>","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":"17 2","pages":"293-298"},"PeriodicalIF":1.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13460695/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148713962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Proton Pump Inhibitors on Blood Glucose in Type 2 Diabetes: A Systematic Review with Meta-analysis.","authors":"Prabhat Kumar Agrawal, Amit Varshney, Siddhant Dev, Nidhi Agastya, Ruchika Garg, Sandipta Kumar Panda, Prashant Gupta","doi":"10.4103/jmh.jmh_210_25","DOIUrl":"10.4103/jmh.jmh_210_25","url":null,"abstract":"<p><p>Proton pump inhibitors (PPIs) are widely prescribed for acid-related disorders, but emerging evidence suggests they may influence glucose metabolism. This meta-analysis evaluates the effect of PPIs on glycemic control in patients with and without type 2 diabetes mellitus (T2DM). We systematically searched PubMed, Cochrane Library, Embase, and Scopus for randomized controlled trials and observational studies reporting fasting blood glucose (FBG), HbA1c, or insulin resistance with PPI use. Risk of bias was assessed using the Cochrane RoB 2.0 tool for randomized trials and the Newcastle-Ottawa Scale for observational studies. Data were synthesized using a random-effects model and expressed as mean differences with 95% confidence intervals (CIs). The review was not prospectively registered in PROSPERO or any other database. Fifteen studies involving 2,038 participants were included in the study. PPI use significantly reduced FBG (mean decrease: 5.32 mg/dL; 95% CI: 2.01-8.63; <i>P</i> = 0.002; 9 studies, <i>n</i> = 1243). HbA1c reductions were observed in some studies (7 studies, <i>n</i> = 1121), but findings were inconsistent. No significant effect was seen on insulin resistance (4 studies, <i>n</i> = 412). Subgroup analyses suggested greater benefits in patients with poorly controlled T2DM. Reported adverse events were mild, including gastrointestinal symptoms and headache. Small sample sizes, study heterogeneity, and moderate risk of bias in some trials limited the certainty of evidence. PPIs may provide modest improvements in glycemic control, particularly among patients with poorly controlled T2DM. While generally safe in the short term, the long-term benefits and risks remain unclear. Regular glucose monitoring may be advisable in diabetic patients on chronic PPI therapy.</p>","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":"17 2","pages":"208-216"},"PeriodicalIF":1.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13460697/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148713931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Prolapse Quality-of-life Questionnaire as a Substitute for Assessing Voiding and Storage Conditions in Patients Undergoing Transvaginal Mesh Surgery.","authors":"Kenji Kuroda, Koetsu Hamamoto, Kazuki Kawamura, Ayako Masunaga, Hiroaki Kobayashi, Keiichi Ito","doi":"10.4103/jmh.jmh_284_25","DOIUrl":"10.4103/jmh.jmh_284_25","url":null,"abstract":"<p><strong>Objectives: </strong>The Prolapse Quality-of-Life Questionnaire (P-QOL) is a validated tool for assessing symptom severity and treatment outcomes in patients with pelvic organ prolapse (POP). This study investigates whether the total score of selected P-QOL component questions can serve as a substitute for the International Prostate Symptom Score (IPSS) plus quality-of-life (QOL) score in patients with POP undergoing transvaginal mesh (TVM) surgery.</p><p><strong>Materials and methods: </strong>The study enrolled 137 patients who underwent TVM at our institution between May 2016 and November 2023. Correlations between the total score of selected P-QOL component questions and the IPSS or QOL score were assessed using Spearman's rank correlation coefficient. The Kruskal-Wallis test was used to compare P-QOL scores between IPSS ≥8 and ≤7 groups and QOL ≥4 and ≤3 groups at baseline and 3, 6, and 12 months postoperatively.</p><p><strong>Results: </strong>Significant correlations were observed between the total score of selected P-QOL component questions and the IPSS or QOL score, both preoperatively and postoperatively. Box plot analyses showed significant differences in P-QOL scores between the IPSS ≥8 and ≤7 groups and the QOL ≥4 and ≤3 groups at all time points. In addition, post-void residual urine volume, P-QOL scores, and IPSS plus QOL scores significantly decreased at 3, 6, and 12 months postoperatively compared with baseline.</p><p><strong>Conclusion: </strong>The P-QOL provides reliable information on voiding and storage conditions preoperatively and postoperatively, making it a viable alternative to the IPSS plus QOL score for evaluating urinary symptoms in patients with POP undergoing TVM.</p>","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":"17 2","pages":"261-268"},"PeriodicalIF":1.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13460842/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148713896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Primary Ovarian Carcinoid Tumor in a Postmenopausal Woman.","authors":"Nalini Sharma, V S Lumthingla, Emihaka Warjari, Biswajit Dey","doi":"10.4103/jmh.jmh_260_25","DOIUrl":"10.4103/jmh.jmh_260_25","url":null,"abstract":"<p><p>Primary ovarian carcinoid tumors are rare neuroendocrine neoplasms, usually presenting as asymptomatic pelvic masses in perimenopausal or postmenopausal women. We report a 55-year-old woman with lower abdominal pain and an enlarging pelvic mass, initially suspected as a uterine fibroid. Intraoperatively, a solid, highly vascular left ovarian mass was identified. A diagnosis of primary ovarian neuroendocrine tumor was established based on histopathology and immunohistochemistry. This case underscores the diagnostic challenge of ovarian masses in postmenopausal women and highlights the importance of considering rare tumors in the differential diagnosis.</p>","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":"17 2","pages":"312-314"},"PeriodicalIF":1.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13460787/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148713966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endometrial Hemangiomatous Polyp Presenting as Postmenopausal Bleeding and Mimicking Uterine Malignancy: A Rare Diagnostic Challenge.","authors":"Akriri Jindal, Ankita Soni, Gargi Kapatia, Manjit Kaur Rana","doi":"10.4103/jmh.jmh_87_26","DOIUrl":"10.4103/jmh.jmh_87_26","url":null,"abstract":"<p><p>Vascular lesions of the uterus are rare, yet remain a potential differential diagnosis for the etiologies of postmenopausal bleeding. Hemangiomas of the uterus are benign neoplasms that can occur in any age group, with a predilection for reproductive age females. It is a benign vascular tumor and should be kept as a differential diagnosis for uterine endometrial mass lesions. Conservative management, such as local excision and laser ablation may help avoid unnecessary hysterectomy in such patients. We report the rare case of a 52-year-old postmenopausal woman who presented with a mass protruding into the vagina associated with bleeding and discharge and was suspected of having an endometrial malignancy that was finally diagnosed as a large endometrial polypoidal hemangiomatous polyp on histopathology. This case report underscores the importance of considering hemangiomatous lesions in the differential diagnosis of uterine polypoidal mass lesions for appropriate management.</p>","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":"17 2","pages":"315-317"},"PeriodicalIF":1.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13460877/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148713226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Breast Cancer Awareness and Self-screening Behaviors among Female Nursing Trainees in Northern India.","authors":"Shivani Singh, Itishree Jena, Ruchika Garg, Urvashi Verma, Shuvadip Basu","doi":"10.4103/jmh.jmh_297_25","DOIUrl":"10.4103/jmh.jmh_297_25","url":null,"abstract":"<p><strong>Background: </strong>Breast cancer remains the most common cancer among women worldwide and is a major contributor to cancer-related mortality in India. Early detection through breast self-examination (BSE) can significantly improve the outcomes. Nursing students, as future health educators, are ideally positioned to promote awareness and early detection practices. This study aimed to assess the knowledge and practice of BSE among female nursing students at Hind Institute of Medical Sciences Ataria, Sitapur.</p><p><strong>Materials and methods: </strong>A cross-sectional study was conducted among 286 female nursing students using a predesigned, prestructured questionnaire assessing knowledge, attitude, and practice (KAP) regarding breast cancer and BSE. Data were analyzed using the SPSS version 2022 and the Chi-square test was used for categorical variables. Scores above the 50^th percentile were considered indicative of good KAP.</p><p><strong>Results: </strong>Out of 286 female nursing students included in the study, the majority (67.13%) were aged above 23 years, only 23.9% of students had good knowledge of breast cancer risk factors, while 35.4% showed adequate knowledge of BSE. Positive attitude toward BSE was seen in 45.1%, yet only 29.2% practiced BSE regularly. The key barriers included the lack of awareness about the technique (73.04%) and the belief that absence of breast problems negates the need for BSE (60.04%).</p><p><strong>Conclusion: </strong>The study reveals a significant gap between knowledge, attitude, and actual practice of BSE among nursing students. Educational interventions and hands-on training are urgently needed to improve breast cancer awareness and encourage regular BSE practices in this crucial group.</p>","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":"17 2","pages":"236-240"},"PeriodicalIF":1.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13460789/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148713853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal Evaluation of a Low Glycemic Load Dietary Intervention: A Multicentric Observational Study in India.","authors":"Prabhat Kumar Agrawal, Ruchika Garg, Ashish Gautam, Nikhil Pursnani, Vineeta Dhyani, Prashant Tiwari","doi":"10.4103/jmh.jmh_332_25","DOIUrl":"10.4103/jmh.jmh_332_25","url":null,"abstract":"<p><strong>Introduction: </strong>Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder marked by insulin resistance and progressive β-cell dysfunction. Medical Nutrition Therapy (MNT) plays a key role in improving glycemic control and reducing comorbid risks. This longitudinal, multicentric observational study assessed the impact of MNT using Diabexy Atta, a culturally tailored low glycemic load (GL) flour, on clinical and biochemical outcomes in real-world Indian settings.</p><p><strong>Materials and methods: </strong>A trained team, supervised by a diabetes specialist, supported participants with home-based assessments and ongoing consultations. Recruitment began in July 2023, with the final visit in January 2025. Of 568 enrolled adults, 512 completed the study. Participants were followed quarterly to monitor glycosylated hemoglobin (HbA1c), FBG, PPBG, liver and kidney function, medication use, and diabetes-related complications. All received personalized diets with Diabexy Atta, and statistical analysis assessed clinical and biochemical changes.</p><p><strong>Results: </strong>Statistical analysis showed significant improvements in glycemic control. Mean HbA1c declined from 8.68% to 6.50% (<i>P</i> < 0.00001), with parallel reductions in FBG and PPBG. Medication use reduced from 59.6% to 41.4%, and complication rates from 28.5% to 12.0% in participant. There was no significant effect on kidney or liver function tests, except for a slight decrease in serum sodium among electrolytes.</p><p><strong>Discussion: </strong>This study suggests that incorporating Diabexy Atta, a culturally familiar low glycemic index food, into MNT is feasible and may improve glycemic and metabolic outcomes in adults with T2DM. Larger and longer studies are needed to confirm these preliminary findings and assess long-term effects.</p><p><strong>Conclusion: </strong>Incorporating Diabexy Atta, low-glycemic-load food, into structured medical nutrition therapy may improve glycemic and metabolic outcomes in adults with Type 2 Diabetes.</p>","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":"17 2","pages":"276-283"},"PeriodicalIF":1.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13460876/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148713949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Disordered Proliferative Endometrium: Time for Evidence-based Clinicopathological Studies.","authors":"Seetu Palo, Mishu Mangla","doi":"10.4103/jmh.jmh_370_25","DOIUrl":"10.4103/jmh.jmh_370_25","url":null,"abstract":"","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":"17 2","pages":"320-322"},"PeriodicalIF":1.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13460701/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148713927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}