Journal of Mid-life Health最新文献

{"title":"Role of Pectoral Nerve Block-II in the Management of Chronic Noncyclical Mastalgia Pain.","authors":"Vanita Ahuja, Rajesh Kumar Bansiwal, Muskan Singla","doi":"10.4103/jmh.jmh_20_25","DOIUrl":"10.4103/jmh.jmh_20_25","url":null,"abstract":"","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":"16 2","pages":"224-225"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12237158/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144601816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Awareness of Menopause and its Associated Factors among Men in Eastern India.","authors":"Smitha Moonjelly Vijayan, Malini Digal, Sadrita Misra, Riya Pan, Renu, Rushali Gajbhiye, Rikta Manna","doi":"10.4103/jmh.jmh_32_25","DOIUrl":"10.4103/jmh.jmh_32_25","url":null,"abstract":"<p><strong>Introduction: </strong>A menopausal transition is a stressful event in a woman's life affecting health and quality of life. Spousal awareness of menopausal changes can help them support their wives in coping with the menopausal transition. No studies have explored men's awareness of menopause in India. Therefore, this study aimed to find the men's awareness of menopause and its associated factors. The study also explored men's awareness of the management of symptoms and partner support.</p><p><strong>Materials and methods: </strong>This cross-sectional study of husbands of menopausal women aged 45-60 years in eastern India evaluated their awareness of menopause by a structured questionnaire. A semistructured interview schedule assessed the men's awareness of menopause, management of symptoms, and partner support.</p><p><strong>Results: </strong>Four hundred and twenty consenting men fulfilling inclusion criteria were recruited for the study. The mean age of the husband was 50.7 ± 3.9 years. The mean age of the wife was 56.6 ± 4.4 years. Most men reported symptoms of joint pain (69.3%), low energy level (68.8%), decreased physical strength (63.3%), tiredness (61%), and low backache (51%) in their wives. The overall knowledge of menopause among husbands was inadequate (91.42%). Men reported that their wives avoiding sexual intimacy (85.7%), irritability (58.6%), and mood swings (43.1%) affected their marital relationship. The husband's knowledge was associated with education (<i>P</i> = 0.014), the wife's education (<i>P</i> < 0.001), occupation (<i>P</i> < 0.001), family income (<i>P</i> < 0.001), and socioeconomic status (<i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>Indian husbands lacked information on menopause. Men need information on menopause to support their menopausal spouses.</p>","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":"16 2","pages":"157-165"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12237183/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144601800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cervical Lymphangiolipoleiomyoma: An Unusual Offender at a Usual Destination - Case Report and Literature Review.","authors":"Md Ali Osama, Kavita Gaur, Kiran Agarwal, Ankita Pandey, Reena Yadav","doi":"10.4103/jmh.jmh_4_25","DOIUrl":"10.4103/jmh.jmh_4_25","url":null,"abstract":"<p><p>Cervical fibroids are relatively rare compared to fibroids that develop in other parts of the uterus, accounting for nearly 1%-2% of all fibroids. They typically originate from the supravaginal or vaginal portions of the cervix. One histological variant is angiolipoleiomyoma (ALLM), a benign mixed mesenchymal neoplasm composed of smooth muscle, mature adipose tissue, and abnormal blood vessels. While there are case reports of ALLM occurring in the kidneys, its presence in the female genital tract is extremely uncommon. Furthermore, here, we present a novel case of a 40-year-old postmenopausal female who presented with a long history of vaginal bleeding. Ultrasound revealed a fibroid located at the cervix; however, with histopathology revealing it to be a lymphangiolipoleiomyoma with a plethora of lymphatics. To the best of our knowledge, this is the first such case described in the medical literature.</p>","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":"16 2","pages":"211-214"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12237200/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144601801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cutaneous Granular Cell Tumor in a Middle-aged Woman: Clinicopathological Insights from a Rare Schwannian Neoplasm.","authors":"Seetu Palo, Monica Mishra, Kailas Anteshwar Mulsange","doi":"10.4103/jmh.jmh_62_25","DOIUrl":"10.4103/jmh.jmh_62_25","url":null,"abstract":"<p><p>We report the case of a 51-year-old female with an unusual presentation of a cutaneous granular cell tumor (GCT) on the lower back. The lesion was asymptomatic, well-defined, and firm, with an initial clinical differential of dermatofibroma, pilomatricoma, or leiomyoma. Histopathological examination revealed a dermal tumor composed of large polygonal cells with granular eosinophilic cytoplasm and uniform nuclei, without atypia or necrosis. Immunohistochemistry confirmed the diagnosis with strong S100 and CD68 positivity. Due to tumor extension tumor extension to the deep resection margin, close follow-up was advised. Accurate diagnosis of cutaneous GCTs relies on histopathology and immunohistochemistry, as clinical and dermoscopic findings are often nonspecific. Complete surgical excision is the primary treatment, with a generally favorable prognosis. Awareness of malignant potential and proper surgical management is crucial for optimal outcomes.</p>","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":"16 2","pages":"218-220"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12237188/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144601803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regenerative Synergy: Combining Platelet-rich Plasma with Transcutaneous Temperature-controlled Radiofrequency for Enhanced Treatment of Stress Urinary Incontinence in Peri- and Postmenopausal Women.","authors":"Smit Bharat Solanki","doi":"10.4103/jmh.jmh_34_25","DOIUrl":"10.4103/jmh.jmh_34_25","url":null,"abstract":"<p><strong>Background: </strong>Stress urinary incontinence (SUI) is a significant health concern among peri-and postmenopausal women, often leading to diminished quality of life. Transcutaneous temperature-controlled radiofrequency (TTCRF) has emerged as a minimally invasive treatment option, but its efficacy may be limited in cases of severe tissue laxity. Platelet-rich plasma (PRP) offers a promising adjunct to enhance tissue remodeling and functional recovery when combined with TTCRF.</p><p><strong>Objective: </strong>This study evaluates the safety, efficacy, and patient-reported outcomes of combining PRP with TTCRF for treating SUI in peri- and postmenopausal women, aiming to address gaps in current therapeutic strategies.</p><p><strong>Materials and methods: </strong>A prospective, randomized controlled trial was conducted involving 80 peri- and postmenopausal women diagnosed with SUI. Participants were randomly assigned to two groups: PRP plus TTCRF (intervention group, <i>n</i> = 40) and TTCRF alone (control group, <i>n</i> = 40). Primary outcome measures included objective improvement assessed via urodynamic studies and subjective improvement evaluated using validated questionnaires (International Consultation on Incontinence Questionnaire - Short Form [ICIQ-SF] and Urogenital Distress Inventory). Secondary outcomes encompassed quality of life (Pelvic Floor Distress Inventory [PFDI-20]) and adverse event reporting. Statistical analyses were performed using SPSS version 27.0, with significance set at <i>P</i> < 0.05.</p><p><strong>Results: </strong>At the 12-month follow-up, the intervention group demonstrated significantly superior outcomes compared to the control group. The mean reduction in ICIQ-SF scores was 9.8 points versus 6.6 points (<i>P</i> = 0.001), and urodynamic parameters improved by 32% more in the PRP plus TTCRF group (<i>P</i> = 0.003). Quality of life, as measured by PFDI-20, showed a 22% greater improvement in the intervention group (<i>P</i> = 0.002).</p><p><strong>Conclusion: </strong>Combining PRP with TTCRF represents an innovative, minimally invasive approach that enhances tissue regeneration and functional recovery in peri- and post-menopausal women with SUI. These findings highlight the potential of PRP to augment the efficacy of TTCRF and warrant further investigation in larger, multicenter trials.</p>","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":"16 2","pages":"179-185"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12237258/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144601815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, Attitudes, and Prevalence of Menopausal Symptoms among Perimenopausal and Postmenopausal Women - A Mixed Method Study from Tamil Nadu.","authors":"Giddaluru Bhavya Muralikrishna, Karthiga Prabhu, Shanmugapriya, Gowthaman Sankar","doi":"10.4103/jmh.jmh_16_25","DOIUrl":"10.4103/jmh.jmh_16_25","url":null,"abstract":"<p><strong>Background: </strong>The age at which menopause occurs varies widely among different populations around the world, and the severity of menopausal symptoms often increases with age. Although menopause is not classified as an illness, it is associated with higher rates of mortality and morbidity among women. Many women go through menopause without adequate knowledge of its health implications. It is essential for women to be informed about the symptoms and complications of menopause so they can manage it effectively and seek appropriate treatment. Without this knowledge and with negative attitudes towards menopause, women may face difficulties during the postmenopausal period.</p><p><strong>Objectives: </strong>This study aims to assess the prevalence of menopausal symptoms and to evaluate the knowledge and attitudes of peri- and postmenopausal women toward menopause.</p><p><strong>Materials and methods: </strong>This mixed-method study was conducted at a single center in a major tertiary care hospital located in Chengalpattu, Kanchipuram, Tamil Nadu, from February 2023 to October 2024. A total of 300 women experiencing perimenopausal and menopausal symptoms were included through convenience sampling. Ethical guidelines established by the institutional ethics committee were followed throughout the study. We utilized the Menopause Rating Scale (MRS), a self-reported and validated tool, to assess the severity of menopausal symptoms reported by the participants.</p><p><strong>Results: </strong>The most common symptoms reported by perimenopausal women included sleep problems (53.4%), hot flashes (50%), anxiety (67.8%), irritability (65.6%), bladder issues (46.7%), and sexual discomfort (44.4%). In postmenopausal women, frequently reported symptoms were joint pain (56.2%), depressive mood (70%), physical and mental exhaustion (63.4%), vaginal dryness (64.8%), and sexual problems (58.1%). Overall, severe menopausal symptoms were more prevalent among postmenopausal women compared to those in the perimenopausal stage, with a statistically significant difference (<i>P</i> < 0.05). Binomial logistic regression analysis showed that age (adjusted odds ratio [AOR] - 1.78), parity (AOR - 2.49), and poor knowledge about menopause (AOR - 2.78) were significant risk factors associated with the severity of menopausal symptoms.</p><p><strong>Conclusion: </strong>This mixed-method study found significant differences in menopausal symptoms, knowledge, and attitudes between peri- and postmenopausal women. In postmenopausal women, higher mean total MRS scores indicated severe somatic, psychological, and urogenital symptoms. We found that menopausal women need tailored education and culturally sensitive support to close knowledge gaps, promote positive attitudes, and meet complex needs.</p>","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":"16 2","pages":"148-156"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12237233/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144601811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Menopause and Mental Health.","authors":"Ruchika Garg, Atul Munshi","doi":"10.4103/jmh.jmh_61_25","DOIUrl":"10.4103/jmh.jmh_61_25","url":null,"abstract":"","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":"16 2","pages":"119-123"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12237151/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144601812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Purple Urine Bag Syndrome in a Bedridden Postmenopausal Woman.","authors":"Prabhat Kumar Agrawal, Ruchika Garg, Nirmal Kumari, Hardeep Bakshi","doi":"10.4103/jmh.jmh_221_24","DOIUrl":"10.4103/jmh.jmh_221_24","url":null,"abstract":"<p><p>A rare condition known as purple urine bag syndrome (PUBS) affects people who are catheterized, particularly elderly females with comorbidities. Urinary tract infections and alkaline urine are frequently linked to the purple staining of the urobag and urinary catheter. It is essential to monitor such patients closely and investigate the underlying cause of PUBS to ensure appropriate management and treatment. We report the case of a 66-year-old female who developed a stroke, became bedridden, and had a Foley catheter <i>in situ</i> for the past 6 months with complaints of purple staining of the urobag and tubing for 5 days.</p>","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":"16 2","pages":"208-210"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12237176/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144601814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tumour Budding with Epithelial Mesenchymal Transition Markers - A Novel Prognostic Tool for Breast Carcinoma.","authors":"Priyadharshini Kumar, Meghashree Vishwanath, Saranyabai Selvaraj","doi":"10.4103/jmh.jmh_77_25","DOIUrl":"10.4103/jmh.jmh_77_25","url":null,"abstract":"<p><strong>Introduction: </strong>Breast cancer is a leading cause of cancer-related deaths among women worldwide. Prior to metastasis, carcinomas undergo epithelial-mesenchymal transition (EMT), a process wherein cancer cells acquire mobility, form tumor buds (TBs), and invade the stroma. The presence and number of TBs are directly proportional to tumor invasion and metastasis. By scoring TBs and using immunohistochemistry (IHC) to detect EMT process, we can identify patients with poor prognosis after surgical resection. This enables early recognition of patients requiring aggressive treatment and follow-up.</p><p><strong>Aim: </strong>The aim of this study was to propose an algorithm for measuring TB and to establish the correlation between TB with EMT markers expression and main clinical parameters.</p><p><strong>Materials and methods: </strong>A retrospective analytical study in an urban tertiary health care center involving 47 cases of invasive breast carcinomas. TB was assessed in Haematoxylin & Eosin stained tissue sections followed by IHC with EMT markers. Association between TB, EMT markers, and main clinical parameters was statistically analyzed using the Chi-square test.</p><p><strong>Results: </strong>Among 47 cases, 30 had mean-low TB score (≤4/ 10HPF) and 17 had mean-high TB score (>4/10 HPF). Tumors with high TB scoring showed strong SNAIL, TWIST, and N-cadherin expression. Tumors with low TB scores showed high E-cadherin expression and low SNAIL, TWIST, and N-cadherin expression.</p><p><strong>Conclusion: </strong>The study established a positive correlation between TB and EMT markers. High TB scores are significantly associated with lymphovascular invasion, lymph node metastasis, and higher tumor grading. Using TB score and EMT markers in breast cancer management can facilitate patient-centered approach.</p>","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":"16 2","pages":"186-191"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12237197/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144601817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Sarcopenia and Its Association with Mental Health Status in Elderly Patients: A Comparative Cross-sectional Study.","authors":"M Yogesh, Anjali Dave, Jimmy Kagathara, Rohankumar Gandhi, Dhruv Lakkad","doi":"10.4103/jmh.jmh_154_24","DOIUrl":"https://doi.org/10.4103/jmh.jmh_154_24","url":null,"abstract":"<p><strong>Background: </strong>Sarcopenia, characterized by loss of muscle mass and function, is a significant health concern in aging populations. While its physical consequences are well-documented, the relationship between sarcopenia and mental health remains understudied. This study aimed to investigate the prevalence of sarcopenia and its association with mental health status, including depression, cognitive function, anxiety, and loneliness, among elderly patients.</p><p><strong>Methodology: </strong>A comparative cross-sectional study was conducted on 407 participants aged ≥65. Sarcopenia was diagnosed using the modified Asian Working Group for Sarcopenia criteria. Mental health was assessed using validated scales: the 15-item Geriatric Depression Scale, the Mini-Mental State Examination, the 7-item Generalized Anxiety Disorder Scale, and the 3-item UCLA Loneliness Scale (UCLA-3). Logistic regression models were used to examine associations between sarcopenia and mental health outcomes.</p><p><strong>Results: </strong>The prevalence of sarcopenia was 49.9% (95% confidence interval [CI]: 45.0%-54.8%), with higher rates in older age groups and women. After adjusting for confounders, sarcopenia was significantly associated with depression (odds ratio [OR]: 2.28, 95% CI: 1.51-3.44, <i>P</i> < 0.001) and cognitive impairment (OR: 1.86, 95% CI: 1.17-2.96, <i>P</i> = 0.009). Associations with anxiety (OR: 1.49, 95% CI: 0.93-2.38, <i>P</i> = 0.095) and loneliness (OR: 1.52, 95% CI: 1.00-2.31, <i>P</i> = 0.049) were observed but did not reach statistical significance.</p><p><strong>Conclusion: </strong>Sarcopenia is highly prevalent among elderly patients and is independently associated with adverse mental health outcomes, particularly depression and cognitive impairment. These findings underscore the importance of integrated physical and mental health interventions in the care of older adults with sarcopenia.</p>","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":"16 1","pages":"51-59"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12052283/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143988625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}