Prevalence of Sarcopenia and Its Association with Mental Health Status in Elderly Patients: A Comparative Cross-sectional Study.

IF 1.2 Q3 OBSTETRICS & GYNECOLOGY
Journal of Mid-life Health Pub Date : 2025-01-01 Epub Date: 2025-04-05 DOI:10.4103/jmh.jmh_154_24
M Yogesh, Anjali Dave, Jimmy Kagathara, Rohankumar Gandhi, Dhruv Lakkad
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引用次数: 0

Abstract

Background: Sarcopenia, characterized by loss of muscle mass and function, is a significant health concern in aging populations. While its physical consequences are well-documented, the relationship between sarcopenia and mental health remains understudied. This study aimed to investigate the prevalence of sarcopenia and its association with mental health status, including depression, cognitive function, anxiety, and loneliness, among elderly patients.

Methodology: A comparative cross-sectional study was conducted on 407 participants aged ≥65. Sarcopenia was diagnosed using the modified Asian Working Group for Sarcopenia criteria. Mental health was assessed using validated scales: the 15-item Geriatric Depression Scale, the Mini-Mental State Examination, the 7-item Generalized Anxiety Disorder Scale, and the 3-item UCLA Loneliness Scale (UCLA-3). Logistic regression models were used to examine associations between sarcopenia and mental health outcomes.

Results: The prevalence of sarcopenia was 49.9% (95% confidence interval [CI]: 45.0%-54.8%), with higher rates in older age groups and women. After adjusting for confounders, sarcopenia was significantly associated with depression (odds ratio [OR]: 2.28, 95% CI: 1.51-3.44, P < 0.001) and cognitive impairment (OR: 1.86, 95% CI: 1.17-2.96, P = 0.009). Associations with anxiety (OR: 1.49, 95% CI: 0.93-2.38, P = 0.095) and loneliness (OR: 1.52, 95% CI: 1.00-2.31, P = 0.049) were observed but did not reach statistical significance.

Conclusion: Sarcopenia is highly prevalent among elderly patients and is independently associated with adverse mental health outcomes, particularly depression and cognitive impairment. These findings underscore the importance of integrated physical and mental health interventions in the care of older adults with sarcopenia.

老年患者肌肉减少症患病率及其与心理健康状况的关系:一项比较横断面研究。
背景:以肌肉质量和功能丧失为特征的肌肉减少症是老龄化人群中一个重要的健康问题。虽然它对身体的影响有充分的记录,但肌肉减少症与心理健康之间的关系仍未得到充分的研究。本研究旨在探讨老年患者肌肉减少症的患病率及其与心理健康状况的关系,包括抑郁、认知功能、焦虑和孤独。方法:对407名年龄≥65岁的参与者进行比较横断面研究。肌少症的诊断采用修改后的亚洲肌少症工作组标准。心理健康评估采用经验证的量表:15项老年抑郁量表、迷你精神状态检查量表、7项广泛性焦虑障碍量表和3项UCLA孤独量表(UCLA-3)。Logistic回归模型用于检验肌肉减少症与心理健康结果之间的关系。结果:骨骼肌减少症的患病率为49.9%(95%可信区间[CI]: 45.0%-54.8%),其中老年人和女性的患病率较高。校正混杂因素后,肌肉减少症与抑郁症(比值比[OR]: 2.28, 95% CI: 1.51-3.44, P < 0.001)和认知障碍(比值比[OR]: 1.86, 95% CI: 1.17-2.96, P = 0.009)显著相关。观察到与焦虑(OR: 1.49, 95% CI: 0.93-2.38, P = 0.095)和孤独(OR: 1.52, 95% CI: 1.00-2.31, P = 0.049)相关,但未达到统计学意义。结论:骨骼肌减少症在老年患者中非常普遍,并独立与不良心理健康结局相关,特别是抑郁症和认知障碍。这些发现强调了综合身心健康干预对老年肌肉减少症患者护理的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Mid-life Health
Journal of Mid-life Health Social Sciences-Health (social science)
CiteScore
1.70
自引率
9.10%
发文量
39
审稿时长
43 weeks
期刊介绍: Journal of mid-life health is the official journal of the Indian Menopause society published Quarterly in January, April, July and October. It is peer reviewed, scientific journal of mid-life health and its problems. It includes all aspects of mid-life health, preventive as well as curative. The journal publishes on subjects such as gynecology, neurology, geriatrics, psychiatry, endocrinology, urology, andrology, psychology, healthy ageing, cardiovascular health, bone health, quality of life etc. as relevant of men and women in their midlife. The Journal provides a visible platform to the researchers as well as clinicians to publish their experiences in this area thereby helping in the promotion of mid-life health leading to healthy ageing, growing need due to increasing life expectancy. The Editorial team has maintained high standards and published original research papers, case reports and review articles from the best of the best contributors both national & international, consistently so that now, it has become a great tool in the hands of menopause practitioners.
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