Journal of Mid-life Health最新文献

{"title":"Dirofilariasis of Breast Mimicking Malignancy – A Rare Entity","authors":"Sudha Srinivasan, M. Srinivaasan","doi":"10.4103/jmh.jmh_109_22","DOIUrl":"https://doi.org/10.4103/jmh.jmh_109_22","url":null,"abstract":"Human dirofilarial infection usually presents as pulmonary coin lesion or as subcutaneous nodule. We report the case of a 60-year-old female presented clinically with swelling in the lower-outer quadrant of the right breast for 2 weeks. Ultrasound reported as atypical lesion suggest fine-needle aspiration cytology (FNAC) correlation and follow-up. Clinical examination – subcutaneous nodule of size 2 cm × 2 cm presents in the lower-outer quadrant. Clinical suspicious of carcinoma was considered and FNAC was done. Aspirated pus-like material and adult worm about 4 cm in length were attached to the needle. Smear was air-dried and stained with Giemsa. Smears were cellular and showed numerous neutrophils, eosinophils, and a few histiocytes in a necrotic background and also noted coiled adult dirofilarial worm. Cellblock was prepared and it showed the cut section of dirofilarial worm with cuticle, muscular layer, intestine, and reproductive tube. We report this case entity due to diagnostic confusion with breast malignancy clinically and radiologically.","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135549940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Xanthogranulomatous Change in a Leiomyoma: First Report of an Extremely Rare Variant/Degenerative Change.","authors":"Mukta Pujani,&nbsp;Kanika Singh,&nbsp;Varsha Chauhan,&nbsp;Aparna Khandelwal,&nbsp;Raina Chawla,&nbsp;Rashmi Ahuja","doi":"10.4103/jmh.jmh_158_22","DOIUrl":"10.4103/jmh.jmh_158_22","url":null,"abstract":"<p><p>Xanthogranulomatous inflammation, a specific form of chronic inflammation, is marked by parenchymal destruction, proliferative fibrosis, and infiltration of typical foamy histiocytes admixed with hemosiderin-laden macrophages and foreign-body giant cells. Myometrial xanthomatosis, a term designated for nodular or diffuse histiocytic hyperplasia of the myometrium, has been reported in association with pregnancy-related procedures. Moreover, a 2-3-fold increase in histiocytic counts has been observed in leiomyomatous areas than in adjacent normal myometrium. The first evidence of collections of lipid-laden macrophages was documented in the form of yellowish degeneration of uterine leiomyomas. We report a case of xanthogranulomatous change in a leiomyoma in a 47-year-old female who presented with abnormal uterine bleeding. To the best of our knowledge, this is the first report of xanthogranulomatous variant/degenerative change in a leiomyoma. This case highlights a new variant of leiomyoma which both gynecologists and pathologists should be aware of as it may pose a diagnostic challenge both clinically as well as pathologically.</p>","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e6/1d/JMH-14-60.PMC10482019.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10180033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Menopausal Duration on Salivary Flow Rate, Tooth Loss, and Oral Health-related Quality of Life in Indian Communities","authors":"N. C. Krupa, H. M. Thippeswamy, Byalakere Rudraiah Chandrashekar, Ravi Kumar Thetakala","doi":"10.4103/jmh.jmh_41_22","DOIUrl":"https://doi.org/10.4103/jmh.jmh_41_22","url":null,"abstract":"Background: Diminishing hormonal levels after menopause evoke physiological changes in a woman’s body. Their effects on the oral cavity are noteworthy, considering symptoms of dry mouth, altered taste perceptions, and tooth loss that may be attributed to reduced salivary flow and alveolar density changes. Aim: The purpose of this study was to assess changes in salivary flow rate, tooth loss, and oral health-related quality of life (OHRQoL) as menopausal duration increased. Materials and Methods: A total of 327 women fulfilling the eligibility criteria were chosen from two villages in the Mysuru district, Karnataka. They were categorized into three groups based on menopausal durations. Salivary flow rates, number of teeth lost, and OHRQoL after menopause were assessed and compared at different menopausal durations. Sociodemographic characteristics and oral hygiene practices were recorded to identify potential confounders. Results: Multivariate analysis demonstrated a significant association between menopausal duration and salivary flow rates (adjusted odds ratio = 2.269). However, no such associations were observed with tooth loss and OHRQoL. Conclusion: Menopausal duration significantly affects salivary flow rate. Its influence on tooth loss and OHRQoL is, however, less evident. Although strong associations cannot be established, the inevitability of the menopausal state advocates consideration of other major yet modifiable factors to improve oral health.","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135550475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intracardiac Leiomyomatosis Arising from a Uterine Leiomyoma - A Rare Case Requiring a Multidisciplinary Laparotomy-Thoracotomy Approach.","authors":"T V Murali,&nbsp;Reshma Sara Thomas,&nbsp;Manjusha Narayana Pilllai,&nbsp;Anitha Gopal","doi":"10.4103/jmh.jmh_47_23","DOIUrl":"10.4103/jmh.jmh_47_23","url":null,"abstract":"<p><p>A 37-year-old lady, when being evaluated in gynecology for pain in the abdomen, was found to have a pelvic mass suspicious of ovarian cancer with markers negative. There was an ovarian vein thrombosis extending to the right atrium in the contrast-enhanced computed tomography scan. A fluorodeoxyglucose positron emission tomography-computed tomography ruled out any other lesions. The patient underwent surgery under general anesthesia with transesophageal echocardiography to monitor the atrial thrombus. Intraoperatively, a retroperitoneal mass is seen arising from the right adnexal region of the uterus extending to the lumbar area. After the hysterectomy, bilateral salpingo-oophorectomy, tumor resection, and baring and looping of the retroperitoneal vessels, a sternotomy was done, and she was put on cardiopulmonary bypass. The tumor thrombus had two limbs both arising from the mass, one through the ovarian and the second through the iliac veins and joining together inside the inferior vena cava (IVC). With the excision of the ovarian vein at its junction, atrial incision, and incisions over the iliac veins and IVC, the thrombus was removed completely in a single sitting. Final histopathology revealed intravenous leiomyomatosis and no malignancy. We report this case as a rare disease, with both ovarian and iliac thrombus being a further rarity and a multidepartment joint effort with a successful outcome.</p>","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/84/08/JMH-14-53.PMC10482015.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10180029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Addressing the Stigma: Empowering Women with Urinary Incontinence.","authors":"Yashodhara Pradeep,&nbsp;Nupur Anand","doi":"10.4103/jmh.jmh_113_23","DOIUrl":"10.4103/jmh.jmh_113_23","url":null,"abstract":"be preceded by a sense of urinary urgency. Cause of detrusor overactivity may be bladder irritation or loss of neurologic control 3. Mixed urinary incontinence is the involuntary leakage of urine caused by a combination of stress and urges urinary incontinence 4. Overflow urinary incontinence – it is the involuntary leakage of urine from an overdistended bladder which occurs due to impaired detrusor contractility and/or bladder outlet obstruction. This may be caused by neurologic diseases such as spinal cord injuries, multiple sclerosis, and diabetes which can impair detrusor function 5. Functional urinary incontinence – it is the involuntary leakage of urine due to environmental or physical barriers to toileting. It is also referred to as toileting difficulty.","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f0/07/JMH-14-1.PMC10482022.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10185623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medical Research in India: Let Us Plug the Holes!","authors":"Maninder Ahuja, Yashodhara Pradeep","doi":"10.4103/jmh.jmh_158_23","DOIUrl":"https://doi.org/10.4103/jmh.jmh_158_23","url":null,"abstract":"The health-care system across India has witnessed a phenomenal change during the past few decades. Besides these improvements, it is time to lay more importance on applied research for increasing the technological advancements in our field. Discussion about clinical research in India brings out a picture of octopus with many tentacles, with a plethora of challenges and roadblocks. Unfortunately, our research topics greatly lack innovations in technological advancements when compared to the West. Paradoxically, Indian scientists are doing great work outside the country! To understand the scope of research, let us first ponder on why do we need research, how to do meaningful research, and how to implement them in the practical scenario. India represents 17.5% of the world’s population but conducts only 1.4% of global clinical research (calculated for the period of August 7, 2011, to August 6, 2012).[1] In contrast to the West, clinical research is a relatively recent enterprise for the Indian society. The picture is more dismal because of the fact that India is a land that witnessed one of the most ancient and flourishing civilizations in the world. It has a rich cultural as well as scientific heritage. A multitude of medical systems developed in India, including Naturopathy, Siddha, and Unani, although Ayurveda dominated the Indian medical system for eras. Ayurveda is a part of the Atharva-Veda and means “Science of Life.”[2,3] After being suppressed by the tyrannical British empire for over two centuries, we lost our system of traditional medicine. The British rule brought in Allopathic system of modern medicine in the country. Medical research has evolved, from individual expert-described opinions and techniques, to scientifically designed methodology-based studies. Evidence-based medicine was established to re-evaluate medical facts and remove various myths in clinical practice. Research methodology is now protocol based with predefined steps.[4,5] We are evidencing increases in life expectancy and that goes hand in hand with revolutionizing research and its impacts on health-care system. Our aim is to reduce morbidity and increase health-adjusted life years (HALYs) and reduce years of life lost to disability. For a healthy health-care system to develop, we need clinical research which can be applied for decision-making by policy planners for implementation of strategies. The health-care structure throughout the world has observed a major revolution with technological progresses. The augmented longevity of the humankind today has been the consequence of decades of global medical research, ensuing in developments in diagnosis and management. Globally, life expectancy has increased by more than 6 years between 2000 and 2019 – from 66.8 years in 2000 to 73.4 years in 2019.[6] Healthy life expectancy (HALE) has also increased from 58.3 years in 2000 to 63.7 years in 2019, and this was due to declining mortality rather than reduced years lived with ","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135549959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Cross-sectional Assessment of Depression, Anxiety, and Cognition in Perimenopausal and Menopausal Women","authors":"Anjalee L. Nagda, Manjiri Chaitanya Datar, Nilesh Mahadeo Naphade, Jyoti V. Shetty","doi":"10.4103/jmh.jmh_34_23","DOIUrl":"https://doi.org/10.4103/jmh.jmh_34_23","url":null,"abstract":"Introduction: Menopausal transition involves failure of ovarian function followed by cessation of menstruation. This has been said to lead to psychiatric comorbidities such as depression and anxiety. Estrogen also has beneficial effects on cognition and thus fluctuation in the same can lead to cognitive decline. Given the number of women undergoing menopause, timely screening of the comorbidities is of importance. Aims and Objectives: Our study aimed at assessment of anxiety, depression, and cognitive impairment in perimenopausal and postmenopausal women presenting in the medicine and gynecology units of a tertiary care hospital. The objectives were to screen the peri- and postmenopausal women presenting with medical and gynecological complaints for the presence of depression and anxiety and assess their cognitive function. To find association of their symptoms with psychosocial and menopausal factors with the psychiatric parameters. Settings and Design: Our study was conducted among the perimenopausal and postmenopausal women visiting gynecology and medicine units in a tertiary care hospital. One hundred and five women in the age group of 45–55 were assessed using a specialized pro forma, Beck’s Anxiety Inventory, Beck’s Depression Inventory, and Addenbrooke’s Cognitive Examination III. Statistical Analysis Used: The results were analyzed using SPSS software (version 20.0). Results: 21.9% of females had moderate levels of anxiety, 24.76% had clinical depression, and 13.33% had mild cognitive impairment. The presence of psychosocial stressors had a significant impact on the anxiety, depression, and cognitive impairment. There was no significant association found between psychiatric parameters and peri- and postmenopausal stage as well between natural or surgical menopause.","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135550474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metabolic Syndrome and Its Components: A Cross-Sectional Analysis of Its Distribution among Pre- and Post-Menopausal Women from Northern India.","authors":"R Nandhini,&nbsp;Banashree Nath,&nbsp;Harsha S Gaikwad,&nbsp;Manjula Sharma,&nbsp;Snehlata Meena","doi":"10.4103/jmh.jmh_38_22","DOIUrl":"10.4103/jmh.jmh_38_22","url":null,"abstract":"<p><strong>Aim: </strong>This study aims to determine the prevalence of Metabolic Syndrome (MS) and recognize its abnormal components in pre and postmenopausal women. We also aim to recognize the abnormal components in postmenopausal women with regard to duration since menopause.</p><p><strong>Materials and methods: </strong>The cross-sectional study was undertaken among pre- and post-menopausal women between 40 and 65 years. Women with MS were identified as per the modified National Cholesterol Education Program Adult Treatment Panel III.</p><p><strong>Results: </strong>A total of 220 women were enrolled comprising 112 premenopausal and 108 postmenopausal women, the prevalence of MS among them being 33% and 51.85%, respectively. Postmenopausal status was found to be independently associated with MS when adjusted for potential confounders (adjusted odds ratios = 14.77, 95% confidence intervals: 1.77-23.33). All the components were proportionately higher in postmenopausal group, the rise in blood pressure (BP) (<i>P</i> = 0.003) and low high-density lipoprotein (HDL) (0.027) being statistically significant. The risk of MS, abdominal obesity, and high BP were highest in <5 years since menopause and decreased thereafter. The risk for low HDL and high triglyceride increased with the number of years since menopause, reaching the peak level in the 5-9-year group and then decreased while the risk of high fasting blood sugar increased reaching peak in the 10-14 years' group.</p><p><strong>Conclusion: </strong>The prevalence of MS is significantly high in postmenopausal women. Screening of women in premenopausal period will give an opportunity to intervene and prevent the menace of MS in Indian women predisposed to abdominal obesity, insulin resistance, and cardiovascular adverse events.</p>","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c6/9a/JMH-13-310.PMC10266565.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9656811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health and Fitness of Postmenopausal Women in Urban versus Rural Gurugram: A Cross-Sectional Study.","authors":"Puneeta Ajmera,&nbsp;Sheetal Kalra,&nbsp;Sadhu Charan Mohapatra,&nbsp;Joginder Yadav","doi":"10.4103/jmh.jmh_86_22","DOIUrl":"10.4103/jmh.jmh_86_22","url":null,"abstract":"<p><strong>Context: </strong>Throughout that process of menopause, a slew of health and fitness problems arise, all of which have a major effect on a woman's standard of living. Health-related physical fitness has been described as an individual's cardiac fitness (aerobic capacity), musculoskeletal fitness, and body composition.</p><p><strong>Aim: </strong>To investigate and compare the health and fitness of postmenopausal women in rural and urban Gurugram.</p><p><strong>Settings and design: </strong>The postmenopausal women of Gurugram, both urban (<i>n</i> = 175) and rural (<i>n</i> = 175), who attended the outpatient department of SGT Hospital in the urban area and a house-to-house survey in the rural area, were the subjects of a cross-sectional survey that was carried out using interviews and a pretested semi-structured questionnaire. Levels of physical activity (PA) were assessed using the International PA Questionnaire (short form). The evaluation of body composition, which was the following step, included determining one's body mass index, waist circumference, and waist<b>-</b>hip ratio. Six-minute Walk Distance Test was used to assess cardiopulmonary fitness. Through chair squat tests, sit-and-reach tests, and grip tests, researchers were able to measure the lower limb strength, flexibility, and upper limb strength of participants.</p><p><strong>Results: </strong>The mean age of subjects was 53.61 ± 5.08 years. Most commonly reported health problems were hypertension (31.3%), hyperlipidemia (21.2%), and diabetes (13.4%). Odds of urban women developing hypertension, hyperlipidemia, and myocardial infarction (MI) were found to be 0.61, 0.42, and 0.96 times higher than rural women. There was a statistically significant difference for the squat test, grip test, body composition parameters, and aerobic capacity; however, no statistically significant difference was seen for sit-and-reach test (<i>P</i> > 0.05).</p><p><strong>Conclusions: </strong>The current research shows that postmenopausal women living in metropolitan areas may face higher health risks since they are more prone to develop hypertension, hyperlipidemia, and MI. Furthermore, all fitness metrics - aside from flexibility - were higher for rural women. The results of the current study highlight the urgent need for health promotion initiatives to enhance the health and fitness of urban postmenopausal women.</p>","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/03/4b/JMH-13-317.PMC10266570.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9656812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Breast Cancer Screening in Perimenopausal Women.","authors":"Nupur Anand,&nbsp;Yashodhara Pradeep,&nbsp;Ayush Srivastava","doi":"10.4103/jmh.jmh_51_23","DOIUrl":"10.4103/jmh.jmh_51_23","url":null,"abstract":"Women of any age with increased risk factors such as positive family history, genetic predisposition with BRCA1 and BRCA2 positivity, or with a history of radiation to the chest wall due to any cause are at high risk of breast cancer. Risk of developing breast cancer can be calculated using the Gail Model, for women above 35 years of age. Using this calculation, if the 5‐year risk of developing a breast cancer is >1.7%, the women is said to have an increased risk of breast cancer, hence has to be screened accordingly.[5]","PeriodicalId":37717,"journal":{"name":"Journal of Mid-life Health","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/82/56/JMH-13-322.PMC10266569.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9660508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}