Current Opinion in Biomedical Engineering最新文献_第5页

Optical point of care devices for diagnosis of urinary tract infections 诊断尿路感染的光学护理点装置

IF 3.9 3区工程技术

Current Opinion in Biomedical Engineering Pub Date : 2023-11-08 DOI: 10.1016/j.cobme.2023.100513

Weiming Xu , Esha Venkat , Hatice Ceylan Koydemir

{"title":"Optical point of care devices for diagnosis of urinary tract infections","authors":"Weiming Xu , Esha Venkat , Hatice Ceylan Koydemir","doi":"10.1016/j.cobme.2023.100513","DOIUrl":"10.1016/j.cobme.2023.100513","url":null,"abstract":"<div><p>Urinary tract infections (UTIs) are common bacterial infections affecting any part of the urinary system. Accurate and rapid UTI diagnosis is crucial for initiating appropriate and effective treatment and preventing further complications. Traditional diagnostic methods based on culturing require specialized expertise, controlled environments for culturing urine specimens, and specific analysis environments, and these methods are time-consuming. In contrast, optical devices offer tremendous advantages, including enhanced sensitivity, user-friendliness, and portability. These devices can be integrated with conventional methods to enhance the accessibility of diagnosis techniques, especially in resource-limited settings. Further research is needed to optimize optical devices' analytical performance and cost-effectiveness to harness their full potential in UTI diagnosis. This review delves into recent advancements in optics-based devices for urinary pathogen detection. After providing a succinct overview of UTIs and existing clinical practices for their detection, diagnosis, and treatment, the most recent studies about optical diagnostic technologies for UTI diagnosis were reviewed, and an exploration of the future prospects and conclusive insights were discussed. Unveiling the potential of optical technology for UTI diagnosis promises to revolutionize healthcare and exemplifies the inexhaustible possibilities at the intersection of science and medicine.</p></div>","PeriodicalId":36748,"journal":{"name":"Current Opinion in Biomedical Engineering","volume":"28 ","pages":"Article 100513"},"PeriodicalIF":3.9,"publicationDate":"2023-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2468451123000697/pdfft?md5=4d80843e0e0fdf3c39596b93289611a9&pid=1-s2.0-S2468451123000697-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135516015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Protein engineering technologies for development of next-generation genome editors 开发下一代基因组编辑器的蛋白质工程技术

IF 3.9 3区工程技术

Current Opinion in Biomedical Engineering Pub Date : 2023-11-01 DOI: 10.1016/j.cobme.2023.100514

Jackson Winter , Shraddha Shirguppe , Pablo Perez-Pinera

引用次数: 0

Single-use biosensors for biomanufacturing: Perspective on the state-of-the-art 用于生物制造的一次性生物传感器:最先进的观点

IF 3.9 3区工程技术

Current Opinion in Biomedical Engineering Pub Date : 2023-10-31 DOI: 10.1016/j.cobme.2023.100512

Zach Hetzler , Noah Lott , Aditi Dey Poonam , Selen Dalgan , Qingshan Wei

引用次数: 0

Microfluidic platforms based on SERS imaging and their point-of-care applications 基于SERS成像的微流控平台及其护理点应用

IF 3.9 3区工程技术

Current Opinion in Biomedical Engineering Pub Date : 2023-10-27 DOI: 10.1016/j.cobme.2023.100510

Hilal Torul , Emine Yıldırım , Uğur Tamer

引用次数: 0

The changing landscape of gene editing tool delivery in neurological disorders 神经系统疾病中基因编辑工具传递的变化前景

IF 3.9 3区工程技术

Current Opinion in Biomedical Engineering Pub Date : 2023-10-12 DOI: 10.1016/j.cobme.2023.100509

Yu-Ju Chen, Abhik Paul, Michael Gregory Collins, Hye Young Lee

引用次数: 0

Biomaterials: Intelligent biomaterials 2023 生物材料:智能生物材料2023

IF 3.9 3区工程技术

Current Opinion in Biomedical Engineering Pub Date : 2023-10-06 DOI: 10.1016/j.cobme.2023.100508

Himansu Sekhar Nanda, Masoud Mozafari, Gulden Camci-Unal, Seeram Ramakrishna, Ravin Narain

引用次数: 0

Futures of BME: Sustainable medical materials 2023 BME的未来:可持续医疗材料2023

IF 3.9 3区工程技术

Current Opinion in Biomedical Engineering Pub Date : 2023-09-28 DOI: 10.1016/j.cobme.2023.100507

Seeram Ramakrishna, Aldo R. Boccaccini, Mina Zare

引用次数: 0

Fueling next-generation genome editing with DNA repair 通过DNA修复推动下一代基因组编辑

IF 3.9 3区工程技术

Current Opinion in Biomedical Engineering Pub Date : 2023-09-22 DOI: 10.1016/j.cobme.2023.100506

Ana Gvozdenovic, Jacob E. Corn

引用次数: 0

Non-invasive brain imaging to advance the understanding of human balance 无创大脑成像促进对人类平衡的理解

IF 3.9 3区工程技术

Current Opinion in Biomedical Engineering Pub Date : 2023-09-16 DOI: 10.1016/j.cobme.2023.100505

Helen J. Huang , Daniel P. Ferris

{"title":"Non-invasive brain imaging to advance the understanding of human balance","authors":"Helen J. Huang , Daniel P. Ferris","doi":"10.1016/j.cobme.2023.100505","DOIUrl":"https://doi.org/10.1016/j.cobme.2023.100505","url":null,"abstract":"<div><p>Humans depend on mobility for social interaction, cognitive development, and health maintenance. Successful mobility requires maintaining balance, which integrates sensory feedback, internal cognitive models of body dynamics, and musculoskeletal actions. There have been great strides in understanding these components of balance control in the last 20 years, but balance deficits persist in a large percentage of the population. We propose that combining non-invasive brain imaging using high-density electroencephalography (EEG) with behavioral and biomechanical measures could reveal unique insights about balance control. Source separation and localization of brain electrical activity during mobile tasks have improved with advancements in electrodes and motion artifact removal. This enables studying naturally occurring balance tasks with and without perturbations to identify the timing, magnitude, and quality of brain processing during balance. Along with efforts toward more inclusive EEG research and open resources, this approach could help diagnose and treat poor balance ability among more people.</p></div>","PeriodicalId":36748,"journal":{"name":"Current Opinion in Biomedical Engineering","volume":"28 ","pages":"Article 100505"},"PeriodicalIF":3.9,"publicationDate":"2023-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49817084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nanotechnology-based strategies for advancing point-of-care lateral flow immunoassays 基于纳米技术的策略推进护理点横向流免疫测定

IF 3.9 3区工程技术

Current Opinion in Biomedical Engineering Pub Date : 2023-09-09 DOI: 10.1016/j.cobme.2023.100504

Peuli Nath, Aniruddha Ray

{"title":"Nanotechnology-based strategies for advancing point-of-care lateral flow immunoassays","authors":"Peuli Nath, Aniruddha Ray","doi":"10.1016/j.cobme.2023.100504","DOIUrl":"https://doi.org/10.1016/j.cobme.2023.100504","url":null,"abstract":"<div><p>Point-of-care tests (POCTs) have the potential to transform medical diagnostics by providing rapid and accurate results at the site of patient care. Of the many different types of POCTs being developed, lateral flow immunoassays (LFIAs) are some of the most widely used due to their simplicity, low cost, and fast response time. Combining recent advances in nanotechnology with the LFIAs has drastically improved their performance in terms of their sensitivity, specificity, and limit of detection, as well as their long-term stability. Nanoparticles, both plasmonic and fluorescent, can be functionalized with antibodies/aptamers and other targeting moieties, thereby enabling the detection of a wide range of biomarkers. Here we discuss various strategies, utilizing nanotechnology, to enhance the performance of these LFIAs in order to break the limits of the currently used conventional assays. Successful deployment of these tests will facilitate widespread use, thereby revolutionizing the current diagnostic and treatment practices, as well as curb future pandemics. Extensive utilization of these tests will also reduce the high medical expenditures, which is a central object of health care reform in every country.</p></div>","PeriodicalId":36748,"journal":{"name":"Current Opinion in Biomedical Engineering","volume":"28 ","pages":"Article 100504"},"PeriodicalIF":3.9,"publicationDate":"2023-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49817085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0