Health Science Reports最新文献

{"title":"The Status and Influencing Factors of Health Behavior Self-Management in Children With Type 1 Diabetes Mellitus: A Cross-Sectional Study","authors":"Jin-Xia Yang,&nbsp;Yue Liu,&nbsp;Su-ying Cao,&nbsp;Guo-ying Wang,&nbsp;Hui-min Zhou,&nbsp;Ya-yun Wang,&nbsp;Zi-sheng Ai","doi":"10.1002/hsr2.70700","DOIUrl":"https://doi.org/10.1002/hsr2.70700","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background and Aims</h3>\u0000 \u0000 <p>To investigate the status of self-management of health behaviors in children with Type 1 diabetes mellitus and to analyze their influencing factors. Self-management skills are essential for disease management in children with Type 1 diabetes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This cross-sectional study was conducted on 132 children with Type 1 diabetes mellitus hospitalized in the Department of Endocrinology and Genetic Metabolism of a tertiary children's hospital. Children were selected from September 2023 to March 2024 by convenience sampling method. A general information questionnaire and the Type 1 Diabetes Behavioral Rating Scale were used to conduct the questionnaire survey.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The mean of health behavior self-management score was (0.60 ± 0.15), and the mean scores of the four dimensions were: daily care behaviors (0.74 ± 0.16), adjustment of diabetes care behaviors (0.29 ± 0.24), diabetes care behavior intervention (0.52 ± 0.25), and other diabetes care behaviors (0.61 ± 0.27) points; one-way analysis of variance showed that the differences in self-management scores of health behaviors of children with Type 1 diabetes mellitus were statistically significant when comparing children with different ages, years since diagnosis, whether they were only children, family structure, whether there was a family member with a diagnosis of diabetes mellitus, literacy level of the parents, and average monthly family income (<i>p</i> &lt; 0.05); the differences between age, whether they were only children, family structure, whether there was a family member with a diagnosed with diabetes mellitus, and average monthly family income were influential factors in the self-management of health behaviors of children with Type 1 diabetes mellitus (<i>p</i> &lt; 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The level of health behavior self-management of children with Type 1 diabetes mellitus is in the middle-low level, and individualized interventions can be carried out for children with different characteristics to promote the improvement of children's ability to manage their disease and improve their quality of life.</p>\u0000 </section>\u0000 </div>","PeriodicalId":36518,"journal":{"name":"Health Science Reports","volume":"8 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/hsr2.70700","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143846036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Addressing Cardiometabolic Challenges in HIV: Insights, Impact, and Best Practices for Optimal Management—A Narrative Review","authors":"Nadine Mugisha,&nbsp;Laura Ghanem,&nbsp;Omar A. I. Komi,&nbsp;Rawan Noureddine,&nbsp;Sanobar Shariff,&nbsp;Magda Wojtara,&nbsp;Mahlagha Mousavi Nanehkeran,&nbsp;Olivier Uwishema","doi":"10.1002/hsr2.70727","DOIUrl":"https://doi.org/10.1002/hsr2.70727","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Introduction&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Since the advent of highly active antiretroviral therapy (HAART), morbidity and mortality rates associated with human immunodeficiency virus (HIV) have significantly decreased leading to prolonged life span of Individuals living with HIV due to the effectiveness of antiretroviral therapy. However, this prolonged lifespan alone does not fully account for the increased incidence of cardiometabolic complications. These complications result from a complex interplay of factors such as chronic inflammation, immune activation, ART-related metabolic effects, and lifestyle changes. which contribute to elevated morbidity and mortality rates, therefore requiring a deeper understanding and setting effective management strategies. This review aims at providing insights and a nuanced understanding of the relationship between HIV and cardiometabolic disorders, explore their clinical implications and adapt optimal management strategies to address the multifaceted challenges at the intersection of HIV and cardiometabolic health, ultimately enhancing patient outcomes and quality of life.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Methods&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Data retrieval was conducted using a predetermined search strategy from medical journals that were published in bibliographical databases like PubMed, Science Direct and Embase. This review systematically considered and synthesized current literature on the association between cardiometabolic challenges and HIV.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Results&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;This review provides a detailed exploration of the interrelationship between HIV and cardiometabolic challenges, with an emphasis on insights, impact, and best practices for optimal management. It underscores the high risk of cardiovascular disease, insulin resistance, dyslipidemia, and lipodystrophy in people living with HIV. Recommendations include evidence-based approaches such as routine cardiometabolic risk. Prevention, screening, management, lifestyle interventions (diet and exercise), and optimizing ART regimens to reduce the negative health outcomes experienced by people living with HIV and to direct clinical practice. To reduce health issues, enhance clinical results, and improve the long-term quality of life for people living with HIV, it is important to early identify cardiovascular risk factors and to follow customized prevention and management methods.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Conclusion&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;This review shows that early detection through regular screening is pivotal through collaboration between healthcare providers, rese","PeriodicalId":36518,"journal":{"name":"Health Science Reports","volume":"8 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/hsr2.70727","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143846240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive Assessment of Genital Infections and Reproductive Health in Women Visiting a Fertility Clinic in Warangal, India—A Case-Control Study","authors":"Naresh Patnaik,&nbsp;Uttam Sarkar,&nbsp;Malathi Jojula,&nbsp;Hema Vaddiraju,&nbsp;Ruchi Jain Dey","doi":"10.1002/hsr2.70659","DOIUrl":"https://doi.org/10.1002/hsr2.70659","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Background&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Female infertility is a global health issue however, its link with genital infections is often overlooked due to asymptomatic nature of infections. Delayed diagnosis and treatment due to absence of reliable point-of-care (POC) tools result in long-term pathological consequences and infertility. This pilot-scale study aims to identify the most noteworthy prognostic symptoms of genital infections that exhibit a significant correlation with reproductive tract disorders and infertility.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Methods&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;We designed a detailed questionnaire and conducted a case-control, observational study with 100 female patients, categorized into infertile (n1 = 62) and healthy groups (n2 = 38) followed by statistical analysis.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Results&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;This study highlights an early onset of infertility (18-25 years). Approximately 27% of the infertile female patients are symptomatic for genital infections, and ~42% exhibit menstrual irregularities. Polycystic ovarian syndrome/disease (PCOS/PCOD, ~30%) appears to be the most predominant disorder, followed by endometrial disorders (~10%) and tubal damage (~8%) in infertile patients. A multivariate correlation analysis revealed a highly significant (&lt;i&gt;p&lt;/i&gt; ≤ 0.05) and strong association (0.15 &lt; Φ ≤ 1.0) between menstrual disorders, endometrial disorders, uterine/tubal blockage, and hormonal disruption with infection-associated symptoms, e.g. vaginitis, cervicitis, pelvic inflammatory disorder (PID), dyspareunia or infections like tuberculosis (TB) &amp; urinary tract infection (UTI).&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Conclusions&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Our study shows a significant contribution of genital infections to female infertility. Nevertheless, a substantial 73% of infertile patients are ineligible for confirmatory diagnosis due to the absence of classical infection symptoms. This underscores the pressing requirement for comprehensive screening strategies for timely management of reproductive health and fertility.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Patient or Public Contribution&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;This study was performed in line with the principles of the STrengthening the Reporting of OBservational studies in Epidemiology (STROBE) guidelines (Supporting Information 1) [1]. The study was performed following an ethical approval of the Institutional Human Ethics Committee. All individuals who participated in the study were fully informed about various asp","PeriodicalId":36518,"journal":{"name":"Health Science Reports","volume":"8 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/hsr2.70659","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143849100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Comprehensive Look at Complementary and Alternative Medicine (CAM) in Saudi Arabia: A Meta-Analysis Study","authors":"Saud M. Alsanad","doi":"10.1002/hsr2.70491","DOIUrl":"https://doi.org/10.1002/hsr2.70491","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background and Aims</h3>\u0000 \u0000 <p>Complementary and Alternative Medicine (CAM) refers to a diverse array of healthcare practices that lie outside conventional Western medicine, including herbal remedies, spiritual healing, and traditional therapies. CAM use has become increasingly prevalent worldwide, driven by cultural, religious, and socioeconomic factors, including in Saudi Arabia. This systematic review and meta-analysis aimed to estimate the prevalence of CAM use in Saudi Arabia and examine the patterns of its utilization across various populations.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A systematic literature review was conducted using the PRISMA framework to identify studies investigating the prevalence and patterns of CAM use among diverse populations in Saudi Arabia. Databases searched included Cochrane, Clinicaltrials.gov, CINAHL, Web of Science, and PubMed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Seven cross-sectional studies, with a total of 4112 participants were included. The studies encompassed a wide range of populations, from adolescents to adults with chronic illnesses. The pooled prevalence of CAM use was calculated to be 0.515 (95% CI [0.373–0.657]) using a random-effects model, showing that 51.5% of the Saudi population engages in CAM practices. Significant heterogeneity was observed across the included studies, likely due to differences in population demographics, CAM definitions, and study methodologies.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The findings emphasize the cultural and religious impact on CAM use and its significance in healthcare delivery. Future research should focus on standardizing CAM definitions, exploring the efficacy of popular therapies, and integrating CAM into conventional healthcare to provide holistic and culturally sensitive care.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Review Registration ID</h3>\u0000 \u0000 <p>PROSPERO CRD42024608257.</p>\u0000 </section>\u0000 </div>","PeriodicalId":36518,"journal":{"name":"Health Science Reports","volume":"8 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/hsr2.70491","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143846248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study Protocol for Applying Trend Impact Analysis in Health Futures Studies: A Methodological Approach Illustrated by HIV/AIDS Forecasting in Iran","authors":"Alikhani Alireza,&nbsp;Hosseini Golkar Mostafa,&nbsp;Sharifi Hamid,&nbsp;Najafi Farid,&nbsp;Haghdoost AliAkbar","doi":"10.1002/hsr2.70670","DOIUrl":"https://doi.org/10.1002/hsr2.70670","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Future planning is critical in the health sector. Data-driven strategies, such as forecasting, assume that past influential forces will persist under similar conditions. Acknowledging significant events and examining their effects can enhance understanding of potential consequences, improving health system planning. This study elucidates the trend impact analysis (TIA) protocol for forecasting and scenario planning in health systems, focusing on the future of HIV/AIDS in Iran.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We utilized the TIA approach, which effectively combines quantitative and qualitative methodologies to enhance the precision of forecasting. TIA is specifically designed to account for the influence of unforeseen events and their potential future occurrences on existing trends, thereby facilitating more reliable and comprehensive projections. The methodology uses historical data to extrapolate and forecast future trends quantitatively. Concurrently, qualitative tools identify potential disruptive or influential events that may impact these trends. The approach generates two principal indices: the Impact Rate, which evaluates both the probability of an event's occurrence and the intensity of its effects on existing trends, and the Corrected Estimate Value, which integrates the Impact Rate with the baseline values based on quantitative forecasting. Researchers incorporate events' impacts into the trend projections by systematically analyzing their nature and magnitude. These methodological steps collectively contribute to formulating well-informed and plausible future scenarios.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The limitations in forecasting the future using quantitative methods and ignoring the effects of unexpected events can lead to “surprises-free” predictions and cause deviations from estimates and plans. To address this, using innovative approaches in the methodology of studies is crucial. It provides the groundwork for intelligent planning to face the future, ensuring the health field remains dynamic and responsive to change and fostering an optimistic outlook.</p>\u0000 </section>\u0000 </div>","PeriodicalId":36518,"journal":{"name":"Health Science Reports","volume":"8 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/hsr2.70670","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143836050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bridging Trust and Collaborative Research in Low-Income Contexts During Public Health Emergencies: A Sierra Leone Case Study","authors":"Ifeolu David,&nbsp;Rohan D. Jeremiah","doi":"10.1002/hsr2.70701","DOIUrl":"https://doi.org/10.1002/hsr2.70701","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background/Aims</h3>\u0000 \u0000 <p>The COVID-19 pandemic has highlighted the critical role of community-centered research in addressing public health challenges, particularly in low-income settings. This study examines the experiences of conducting a mixed-methods COVID-19 vaccine uptake study among healthcare workers in Sierra Leone—a country with a history of infectious disease outbreaks and a fragile healthcare system.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Twenty-four (24) in-depth qualitative interviews and 1,001 healthcare workers across six districts completed a 109-item quantitative survey. Thematic analysis was conducted for the qualitative data, while the online survey data were analyzed in Stata for descriptive and inferential statistics.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The qualitative results showcased how direct researcher-community interactions encouraged participation, even without financial incentives. Conversely, the quantitative results uncovered mistrust and limited engagement, mitigated primarily through financial incentives and active stakeholder involvement. Integrating these research methods provided a comprehensive understanding of the factors influencing vaccine uptake and the broader research process.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The paper yields practical insights into navigating community-based research's complexities amid a global pandemic. The results offer critical insights into pandemic preparedness and equity-informed methodologies for global health researchers and public health practitioners working in low-income settings. Community engagement and trust-building were core elements of vaccine uptake research. This case study contributes to the global health research discourse by emphasizing the need for locally adaptable research methodologies amid a public health emergency.</p>\u0000 </section>\u0000 </div>","PeriodicalId":36518,"journal":{"name":"Health Science Reports","volume":"8 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/hsr2.70701","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143836210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Asthma, Allergic Rhinitis, and Eczema in Schoolchildren From Huambo, Angola: A Cross-Sectional Study","authors":"Elias José Gonçalves,&nbsp;Crícia do Espírito Santo Nunda,&nbsp;Cruz dos Santos Sebastião,&nbsp;Margarete Lopes Teixeira Arrais","doi":"10.1002/hsr2.70678","DOIUrl":"https://doi.org/10.1002/hsr2.70678","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background and Aims</h3>\u0000 \u0000 <p>Asthma is the most common chronic non-communicable disease in children with a higher prevalence in high-income countries, however, the majority of asthma-related deaths occur in low- and middle-income countries, including Angola. Therefore, we aimed to investigate the prevalence of asthma and allergic diseases among schoolchildren in Huambo, Angola's fourth most populous province.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A cross-sectional study was carried out in April and May 2022 among schoolchildren aged 6–14 using the ISAAC methodology. The questionnaire included questions on asthma, allergic rhinitis, and eczema symptoms, as well as environmental exposure and risk factors. Twenty schools were randomly selected. <i>χ</i>² tests and univariate and multivariate logistic regression analyses examined associations between categorical variables. A <i>p</i>-value of &lt; 0.05 was considered significant.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The final sample included 1807 schoolchildren, all of whom lived in an urban area, 52.2% were girls, with a mean age of 11.9 ± 2.92 years, and 21.3% of whose parents were illiterate. Current asthma, allergic rhinitis, and eczema prevalence were 7.7%, 23.7%, and 15.8%, respectively, and none of the schoolchildren with asthma were regularly followed up by a physician or were medicated for asthma. The mother's educational level was positively associated with asthma (<i>p</i> = 0.022) and eczema (<i>p</i> = 0.042) prevalence, while having allergic rhinitis was positively associated with older schoolchildren (<i>p</i> &lt; 0.001). Concerning the risk factors studied, schoolchildren with allergic rhinitis [AOR: 3.88 (95%CI 2.67–5.64); <i>p</i> &lt; 0.001] and eczema [AOR: 2.99 (95%CI 2.02–4.41); <i>p</i> &lt; 0.001] had a significant risk of having asthma.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Our findings indicate a significant burden of asthma, allergic rhinitis, and eczema among the schoolchildren studied, underscoring the need to address this critical public health issue.</p>\u0000 </section>\u0000 </div>","PeriodicalId":36518,"journal":{"name":"Health Science Reports","volume":"8 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/hsr2.70678","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143836319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Breast Reconstruction After Mastectomy Using a Deep Inferior Epigastric Perforator (DIEP) Flap: Clinical and Medico-Legal Insights From a Four-Year Study","authors":"Demetris Savva,&nbsp;Giulio Nittari,&nbsp;Filippo Gibelli,&nbsp;Giovanna Ricci,&nbsp;Savvas Dalitis,&nbsp;Antonia Fotiou,&nbsp;Phanos Michael","doi":"10.1002/hsr2.70499","DOIUrl":"https://doi.org/10.1002/hsr2.70499","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>Breast reconstruction after mastectomy is nowadays a gold standard in therapy of breast cancer patients. Free deep inferior epigastric perforator (DIEP) flap reconstruction is a favorable method when traditional implants fail or are not viable, especially after radiotherapy. The aim of this paper is to present the results of a case series study of 40 patients operated on with DIEP flap from January 2020 to October 2023, in Plastic, Reconstructive and Aesthetic Surgery Department in Nicosia General Hospital, Cyprus, complications and wound management, reoperation rates, as well as to examine these results from a medico-legal perspective, to highlight the most significant medico-legal implications of this demanding, surgical procedure.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>Forty patients were included in this study with unilateral or bilateral free DIEP reconstruction, from January 2020 to October 2023, in Plastic, Reconstructive and Aesthetic Surgery Department in Nicosia General Hospital, Cyprus. Demographics, preoperative conditions, hospitalization days, complication rates, and reoperation rates were analyzed as well as satisfaction rates of patients were evaluated.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>This original article highlighted a number of issues of strict medico-legal interest, including the importance of informed consent in the case of demanding procedures for reconstructive and esthetic purposes, the assessment of standards of care in the evaluation of medical liability, and the existence of an obligation of means or results on the reconstructive surgeon's part.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>DIEP breast reconstruction after mastectomy is a challenging but safe and with well postoperative results operation that should be employed in cases traditional implant reconstruction fail or not feasible due to other parameters. Innovative and demanding reconstructive, esthetic surgery procedures are characterized by particularly significant aspects of medico-legal interest, which deserve careful consideration by both the scientific community and patients involved.</p>\u0000 </section>\u0000 </div>","PeriodicalId":36518,"journal":{"name":"Health Science Reports","volume":"8 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/hsr2.70499","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143840640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Burn Injuries in Primary School Children: A Multicenter Epidemiological Study Between 2009 and 2023","authors":"Abdolkhalegh Keshavarzi,&nbsp;S. Yasamin Parvar,&nbsp;Mandana Goodarzian,&nbsp;Aram Maaroufi,&nbsp;MReza Goodarzian,&nbsp;Gholam Reza Motazedian,&nbsp;Mitra Zardosht","doi":"10.1002/hsr2.70674","DOIUrl":"https://doi.org/10.1002/hsr2.70674","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Burns in pediatric populations lead to severe cosmetic and traumatic injuries, impacting their future. Understanding burn causes and predisposing factors is essential for prevention, particularly in primary school-aged children who are beginning their social and educational lives.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>This study evaluates the epidemiology and etiologies of burn injuries among primary school children from 2009 to 2023.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This retrospective study assesses burn data, including age, home place, burn etiology, final status, injury location, injury type, TBSA (Total Body Surface Area), and LOS (Length of Stay). Data were extracted from the burn research data center and analyzed using univariate and multivariate logistic regression analyses to identify independent survival predictors in children aged 7–14 years over a 14-year period admitted to the Amir-al-Moemenin and Ghotb al-Din-e-Shirazi burn hospitals.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of the 8510 patients admitted, 571 were aged 7–14 years, with a male-to-female ratio of 2.2 and a mean age of 10.1 years. Flame burns were the most common (51.7%), with winter being the peak season (27.7%). Accidental burns (<i>p</i> = 0.003) in outdoor places (<i>p</i> &lt; 0.001) and urban areas were significantly more common among males. Females had a significantly higher mean TBSA%. Over 85% of patients were released or discharged, with a mortality rate of 13.2%. TBSA% in flame burns and LOS in chemical and electrical burns were significantly higher (<i>p</i> &lt; 0.001). Univariate analysis identified age, male gender, accidental occurrence, rural living, TBSA%, and LOS as significant predictors of survival. Multivariate analysis confirmed TBSA% and LOS as strong survival predictors.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Flame burns are the primary etiology, occurring mostly outdoors, in younger males living in urban areas, and predominantly accidental. Further studies in various pediatric groups are necessary to reduce the financial, educational, and health complications associated with burns.</p>\u0000 </section>\u0000 </div>","PeriodicalId":36518,"journal":{"name":"Health Science Reports","volume":"8 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/hsr2.70674","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143836209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Prospective Open-Label Study of Tolerance and Effectiveness of Sequential Dermocosmetic Treatments Combining Poly-l-Lysine Biovectors With Vitamins A and C","authors":"Bertrand Nassar,&nbsp;Hafid Belhadj-Tahar,&nbsp;Weiyang Jin,&nbsp;Guanghua Yang","doi":"10.1002/hsr2.70676","DOIUrl":"https://doi.org/10.1002/hsr2.70676","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background and Objectives</h3>\u0000 \u0000 <p>Atopic dermatitis (AD) is a common chronic inflammatory skin condition, affecting 15%–20% of children and up to 10% of adults. It has a significant impact on patients' quality of life and represents a considerable burden on healthcare systems. Management strategies aim to restore the skin barrier, reduce inflammation, and achieve physiological and homeostatic balance. This study evaluates the safety and efficacy of a new dermocosmetic formulation combining poly-<span>l</span>-lysine biovectors with vitamins A and C.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A single-arm, open-label study was conducted on 20 patients diagnosed with AD, including 14 women and 6 men aged between 24 and 63, with skin phototypes of Fitzpatrick I–VI. Treatment involved sequential application of poly-<span>l</span>-lysine G2/vitamin C in the morning and poly-<span>l</span>-lysine G3/vitamin A in the evening for 28 days, on the face, hands, and body. Outcomes were assessed using the Dermatology Life Quality Index (DLQI) and SCORAD scores. Additional assessments included a visual analog scale for pruritus and sleep disturbance, as well as patient self-report questionnaires on skin improvement and treatment satisfaction.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The treatment was well-tolerated, with no adverse effects and no relapses of AD. After 28 days, patients showed a significant reduction in DLQI (−61.8%, Cohen's <i>d</i> = 1.20) and SCORAD (−41.8%, Cohen's <i>d</i> = 1.05) scores. Objective improvements included reductions in erythema (−50%), dryness (−60%), and pruritus (−50%).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This study demonstrates the potential of poly-<span>l</span>-lysine-based dermocosmetics combined with vitamins A and C to improve the symptoms and quality of life of patients suffering from AD. The formulations were well-tolerated and effective in restoring the skin barrier and reducing inflammation. Further large-scale controlled studies are needed to validate these results and explore long-term efficacy.</p>\u0000 </section>\u0000 </div>","PeriodicalId":36518,"journal":{"name":"Health Science Reports","volume":"8 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/hsr2.70676","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143836149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}