Journal of Hazardous Materials最新文献

{"title":"Electrochemiluminescence and Fluorescence Dual-Mode Monitoring of Aflatoxin B1 Production Based on Single Ru-MOF Particles and FITC Luminophores","authors":"Haijie Lu, Zheng Xu, Hui Xu, Jun Zhang, Hong Zhou, Jing Liu","doi":"10.1016/j.jhazmat.2025.138275","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2025.138275","url":null,"abstract":"Herein, an electrochemiluminescence (ECL) and fluorescence (FL) dual-mode imaging biosensing platform was developed for onsite and dynamic monitoring of aflatoxin B1 (AFB1) production in the corn molding process. Zinc metal organic framework structures encapsulated with Ru(bpy)₃²⁺ (Ru-MOF) were employed as ECL signal probes for single particle imaging with stable luminescent intensity and high emission efficiency. Fluorescein Isothiocyanate (FITC) luminophores, served as fluorescent probes, were conjugated with AFB1 aptamer modified on the electrode surface, which enabled the observation of green luminescent spots in FL mode. When exposed to target AFB1, FITC luminophores detached from the surface of electrode, leading to a notable decrease in the number of green luminescent spots. Single Ru-MOF particles were then immobilized onto the surface of electrode through DNA coupling and discernible luminescent spots could be watched in ECL mode. Under optimal circumstances, a dual-mode imaging platform was constructed for AFB1 determination with a linear relationship of 1.0 fg/mL to 1.0<!-- --> <!-- -->pg/mL in both ECL and FL mode. The detection limit (LOD) was 0.89 fg/mL in FL mode and 0.84 fg/mL in ECL mode, which demonstrated superior sensitivity. The imaging biosensor was established for dynamic tracking of AFB1 production in corn molding process. The results showed that aflatoxin production occurred more rapidly at damaged areas of the corn compared to areas with intact surfaces. The intact corn got moldy on the third day and its surface AFB1 concentration was calculated as 14.16 fg/mL. Combining the ECL and FL imaging technology with dual-mode biosensing, this work achieves high sensitivity, accuracy and capability of dynamic monitoring for AFB1 sensing which provides innovative ideas for the rational design of aflatoxin sensors, and holds substantial promise in food safety.","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"6 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2025-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143824970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Testing the hypothesis of fluoride and uranium co-mobilization into groundwater by competitive ion exchange in alluvial aquifers of Southern Punjab, India","authors":"Naved Alam, Ajit Kumar, Deependra Kumar Singh, Satish Kumar, Mohd Amir Husain, Harald Neidhardt, Elisabeth Eiche, Michael Marks, Ashis Biswas","doi":"10.1016/j.jhazmat.2025.138267","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2025.138267","url":null,"abstract":"Co-mobilizing fluoride (F^-) and uranium (U) into groundwater poses a drinking water quality problem globally. Competitive ion exchange with aquifer sediments has been hypothesized to cause their co-mobilization. However, this hypothesis has been postulated merely based on correlations of F^- and U with other groundwater parameters without characterizing that F^- and U were present as exchangeable in the aquifer sediments. The present study, therefore, tested this hypothesis by determining the abundance and association of F^- and U in the aquifer sediments and correlating these data with the groundwater composition in the alluvial aquifers of southern Punjab, India, where the groundwater contamination by F^- and U is severe. Our results support the hypothesis that competitive ion exchange can co-mobilize F^- and U into groundwater. However, the specific ion exchange reaction involved in the F^- and U mobilization can differ. In the study area, the U mobilization into groundwater was linked to increased ionic strength due to the increase in concentration of any ionic species. However, the mobilization of F^- was explicitly linked to the changes in OH^- and HCO₃^- concentrations rather than the overall ionic strength. Bicarbonate was the most critical ionic species that could cause F^- and U co-mobilization.","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"52 2 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143823080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of expanded polytetrafluoroethylene hollow fiber membranes for membrane Fenton oxidation in wastewater treatment","authors":"Yong Zhang, Tiancheng Chu, Kuiling Li, Hongxin Liu, Zhichao Zhao, Xiaohui Wu, Jun Wang","doi":"10.1016/j.jhazmat.2025.138247","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2025.138247","url":null,"abstract":"The Fenton advanced oxidation technology is widely regarded as an effective solution for treating refractory industrial wastewater. However, a major challenge lies in the substantial generation of hazardous sludge. In this study, a novel membrane Fenton (MF) technique was developed, enabling efficient reuse of Fenton sludge and significantly reducing its discharge. To ensure stable and efficient performance under Fenton reaction conditions, expanded polytetrafluoroethylene hollow fiber membranes were fabricated by optimizing the stretching conditions. These membranes feature high porosity, low critical water yield pressure, high mechanical strength, and excellent oxidative resistance. The optimized membrane exhibited high water permeability (200.9 kg/m²h) and low effluent turbidity (1.31 NTU), making it suitable for Fenton sludge concentration. Subsequently, a sequential batch MF technique was designed to integrate the Fenton reaction, sludge concentration, and sludge reuse within a single reactor. The MF process reduced ferrous ion input and hazardous sludge production by 50 %, while achieving a comparable chemical oxygen demand removal efficiency (62.1–64.9 %) to the conventional Fenton process for metronidazole pharmaceutical wastewater. Furthermore, no irreversible membrane contamination occurred during eight continuous reaction batches. The prepared membranes also exhibited excellent chemical and mechanical stability, with no property changes detected after 40 days of immersion in the oxidant.","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"25 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143823089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Selective oxidation of ammonium to nitrogen with VUV/UV/Cl⁻ process: efficiency, pathway and mechanism","authors":"Lingdan Wang, Bing Chen, Gaozu Liao, Jing Wang, Weirui Chen, Xukai Li, Yiming Tang, Xi Wang, Laisheng Li","doi":"10.1016/j.jhazmat.2025.138257","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2025.138257","url":null,"abstract":"Conversion of chloride ions (Cl⁻) into reactive chlorine species (RCS) is an effective strategy for ammonium (NH₄⁺-N) selective oxidation to nitrogen (N₂) under high salinity conditions. Herein, vacuum ultraviolet (VUV) irradiation was introduced for NH₄⁺-N removal in simulated recirculating mariculture systems (RMS) water treatment. Complete oxidation of NH₄⁺-N and 88.3% N₂ selectivity were achieved for VUV/UV/Cl⁻ process. Mechanism analysis revealed that Cl⁻ were effectively converted into RCS under VUV irradiation and chlorine oxide radical (ClO^•) was the predominant RCS responsible for NH₄⁺-N removal. The pathway of NH₄⁺-N oxidation was proposed as chlorination because chloramine was identified as the main intermediate. Influence factor investigation indicated that Cl⁻ and bicarbonate (HCO₃⁻) could significantly promote the removal of NH₄⁺-N in VUV/UV/Cl⁻ process due to acceleration of ClO^• generation. Ultimately, the NH₄⁺-N removal performance of VUV/UV/Cl⁻ process in practical application was also investigated. The results showed that not only NH₄⁺-N in actual seawater or RMS could be converted effectively to N₂, but also nitrite (NO₂⁻-N) and partial nitrate (NO₃^⁻-N) could be removed efficiently by VUV/UV/Cl⁻ process. Hence, the VUV/UV/Cl⁻ process has promising potential in NH₄⁺-N and total nitrogen (TN) removal for RMS water treatment.","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"5 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143823079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polystyrene Nanoplastics Chronic Exposure Cause Zebrafish Visual Neurobehavior Toxicity Through TGFβ-Crystallin Axis","authors":"Jian Lin, Dongliang Pan, Yangfan Zhu, Baoguo Shen, Zhenkai Sun, Yi Zheng, Yuying Yin, Changjiang Huang, Wencan Wu, Yang Song, Jiangfei Chen","doi":"10.1016/j.jhazmat.2025.138255","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2025.138255","url":null,"abstract":"The ubiquitous presence of micro-and nanoplastics (MNPs) in the environment and everyday products has attracted global attention for their hazardous risks. However, the effects and underling mechanisms of MNPs chronic exposure on behavioral/visual changes of the adult and offspring remain unclear. The present study investigated the impact of polystyrene (PS) nanoplastics of 80, 200 and 500<!-- --> <!-- -->nm diameters on zebrafish visual behaviors at an environmentally relevant concentration of 0.1<!-- --> <!-- -->mg/L. Exposure to PS resulted in zebrafish hyperactivity, enhanced aggression, compacted shoaling and less sociability, and especially suppressed the adult optokinetic response (OKR) and offspring larval phototactic behavior, with the 500<!-- --> <!-- -->nm PS being the most detrimental. Histopathological analysis showed 500<!-- --> <!-- -->nm PS caused significant structural damage to the retina's pigment epithelium (RPE), photoreceptor cells (PRC), and crystalline lens. Fluorescence observation found PS accumulation in retinal layers correlated with reduced oligodendrocyte transcription factor 2 (Olig2) in optic nerve. Further transcriptomic analysis of the adult eye tissue revealed that 500<!-- --> <!-- -->nm PS affected the transforming growth factor β (TGFβ) and phototransduction signaling pathways, dysregulated visual perception and lens development, potentially leading to dysopia in zebrafish. Specifically, TGFβ and its regulated-extracellular matrix/inflammatory factors and crystallin genes were increased, but the visual perception genes were decreased, suggesting the TGFβ-crystallin axis disorders contribute to the eye dysfunction induced by PS exposure. Collectively, our results provide new evidence revealing the molecular mechanisms of PS-induced visual toxicity and neurobehavioral changes highlighting that MNPs may pose a risk to vision health.","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"60 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143823094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mercury, Methylmercury, and Its Fractions at the Base of the Trophic Pyramid of the Maritime Antarctic Ecosystem of Admiralty Bay","authors":"Ewa Korejwo, Dominika Saniewska, Agnieszka Jędruch, Aleksandra Zgrundo, Luiza Bielecka, Piotr Paneth, Piotr Balazy, Jacek Bełdowski, Michał Saniewski","doi":"10.1016/j.jhazmat.2025.138268","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2025.138268","url":null,"abstract":"Mercury (Hg) pollution in polar regions is a critical environmental concern, exacerbated by glacier melting due to climate change. This study investigated the impact of glacial meltwater on total mercury (THg), methylmercury (MeHg), and various Hg fractions levels in seawater, suspended particulate matter, and microplankton in Admiralty Bay, Antarctica. Stable isotope analyses of carbon and nitrogen complement Hg measurements, providing insights into food web dynamics and pollutant transfer. The average THg concentration in water samples from creeks, which may represent runoff from melting glaciers and snow, was 2.5 times higher than in sea water from Admiralty Bay. The proportion of methylmercury in total mercury varied depending on the environmental component: in water, it was 1.1%; in SPM, 0.7%; and in microplankton, 2.4%. Increased microplankton biomass, which provides a larger surface area, enhanced the proportion of adsorbed Hg_F1, in microplankton, indicating that mercury adsorbs onto available planktonic surfaces. This research enhances our understanding of Hg cycling in Antarctic ecosystems and underscores the implications of climate change for Hg contamination, with potential effects on marine food webs and human health.","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"110 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143823081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Design of an Efficient Nitrate Reduction Electrocatalyst via Active Site Identification and Optimization in Fe3O4","authors":"Fangchao Lou, Longbing Zuo, Shuo Geng, Jintong Guo, Jun Ma","doi":"10.1016/j.jhazmat.2025.138228","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2025.138228","url":null,"abstract":"Identifying the active sites of an electrocatalyst is crucial for understanding and improving the electrocatalytic performance of electrocatalyst. Fe₃O₄, as an efficient electrocatalyst for the electrocatalytic NO₃^- reduction reaction (eNO₃^-RR), has been extensively investigated while the genuine active site is unclear. In this study, we demonstrated that the eNO₃^-RR activity of Fe₃O₄ is not influenced by the geometric position of Fe ions but is highly dependent on the valence state of iron. Specifically, eNO₃^-RR is more likely to occur on Fe²⁺ sites compared to Fe³⁺ sites. The FeCo₂O₄ catalyst, synthesized by substituting inert Fe³⁺ with highly active Co³⁺, exhibits exceptional performance. At an electrode potential of -0.6<!-- --> <!-- -->V <em>vs.</em> RHE, the Faradaic efficiency for ammonia production reached 98.90%, with an ammonia generation rate of 29.20<!-- --> <!-- -->mg<!-- --> <!-- -->h^-1 cm^-2. Furthermore, when utilized as the cathode material in a Zn-NO₃^- battery, the peak power density reaches 4.7<!-- --> <!-- -->mW<!-- --> <!-- -->cm^-2. Our study not only elucidates the correlation between the valence state of Fe ions in Fe₃O₄ and the intrinsic activity of eNO₃^-RR, but also demonstrates that the FeCo₂O₄ catalyst synthesized via cation substitution exhibits superior performance. This finding offers a novel and effective strategy for the rational design of high-performance spinel electrocatalysts.<h3>Environmental implication</h3>Nitrate pollution represents a significant environmental challenge confronting the global community. The traditional Haber-Bosch process, as the cornerstone technology for ammonia synthesis, has been instrumental in supporting modern agriculture and industrial development. However, its high energy consumption, substantial carbon emissions, and dependence on fossil fuels are at odds with the principles of sustainable development. Electro-catalytic nitrate reduction technology provides a novel solution to these challenges. This study identified the active sites of Fe₃O₄ and developed a FeCo₂O₄ nitrate reduction catalyst that exhibited exceptional performance in the nitrate reduction reaction. This catalyst not only holds considerable promise for mitigating nitrate pollution but also has the potential to advance the development of green ammonia synthesis and sustainable nitrogen cycling, thereby exerting profound impacts on environmental protection and energy sustainability.","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"43 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143823087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced Sulfamethoxazole Removal in Water and Wastewater by Ferrate(VI)/Perborate System via Borate Buffering","authors":"Zihe Chen, Cong Li, Jingzhen Su, Zhenming He, Jiani Xu, Yulin Bian, Hyunook Kim, Xiaohong Guan","doi":"10.1016/j.jhazmat.2025.138261","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2025.138261","url":null,"abstract":"Ferrate(VI) is prone to self-decomposition in water, leading to the loss of active substances Fe(V) and Fe(IV). Therefore, the use of Fe(VI) alone has limited practical applicability in municipal wastewater and industrial wastewater treatment scenarios due to its insufficient pollutant removal efficiency. This study discussed the removal efficiency of the Fe(VI)/perborate system for sulfamethoxazole and other 6 drugs in pure water within 5<!-- --> <!-- -->minutes, and the removal efficiency of the Fe(VI)/perborate system for sulfamethoxazole in effluent and secondary effluent in a wastewater treatment plant (WWTP) within 5<!-- --> <!-- -->minutes. Results show that the sulfamethoxazole removal efficiency reached 88.63% in the influent of Lijiang B WWTP and 79% in the secondary effluent of Wuhan WWTP. The removal efficiency of sulfamethoxazole in pure water reached 25.8% in 5<!-- --> <!-- -->minutes. This finding is explained by the buffering with the borate produced by the hydrolysis of Fe(VI)/perborate, which maintains the pH around 9 and, in turn, inhibits the reduction of active species. Moreover, H₂O₂, ¹O₂, and O₂^•- radicals generated by Fe(VI)/perborate accelerate the activation of Fe(VI), and the Fe²⁺ produced in the system participates in Fenton reactions with H₂O₂. This study offers a novel approach for using ferrate in practical water treatment.","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"14 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143820016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combined exposure of polystyrene nanoplastics and silver nanoparticles exacerbating hepatotoxicity in zebrafish mediated by ferroptosis pathway through increased silver accumulation","authors":"Ying Cheng, Ziyi Fan, Ji Wu, Lihang Li, Guanchen Cheng, Jin Yan, Zejun Wang, Xuedong Wang, Qiuhui Qian, Huili Wang","doi":"10.1016/j.jhazmat.2025.138260","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2025.138260","url":null,"abstract":"Silver nanoparticles (AgNPs) are extensively utilized for their antibacterial properties, leading to their release into the environment and subsequent bioaccumulation and biomagnification within the food chain. Polystyrene nanoplastics (PSNPs), as emerging pollutants, act as carriers for contaminants and alter their transformation processes. However, the toxicological effects and underlying mechanisms associated with the coexistence of these pollutants remain largely unexplored. Herein, the hepatotoxic effects and underlying mechanisms of acute combined exposure to PSNPs and AgNPs were explored using zebrafish as a model organism. After exposed to PSNPs and AgNPs, the larvae (120<!-- --> <!-- -->hours post-fertilization) exhibited lipid metabolism disorders, increased oxidative stress, hepatomegaly, and liver dysfunction, with these effects being more pronounced than those observed with AgNPs exposure alone. This increase in hepatic toxicity may be due to the enhanced accumulation of AgNPs under combined exposure. Mechanistic investigations revealed that co-exposure led to a significant elevation in malondialdehyde and Fe²⁺ levels, a loss of mitochondrial cristae and a decrease in membrane potential, along with the abnormal expression of ferroptosis-related genes, which are hallmark indicators of ferroptosis. Furthermore, the introduction of the ferroptosis inhibitor deferoxamine alleviated all observed hepatotoxic phenotypes, thereby confirming that PS+AgNPs co-exposure induced liver injury through the ferroptosis pathway.<h3>Environment implication</h3>As antibacterial agents, silver nanoparticles are prevalent in the environment and pose ecological risks. Simultaneously, polystyrene nanoplastics often serve as carriers, altering the biotoxicity of adsorbed pollutants. However, research on the toxicity of nanomaterials adsorbed by nanoplastics is scarce. This study examined the increased toxicity on zebrafish livers under co-exposure to environmentally relevant concentrations of AgNPs and no observed effect concentrations of PSNPs. It proposed a novel insight that co-exposure to PSNPs and AgNPs induced liver injury in zebrafish through ferroptosis. This study provides reference for assessing the ecological risks and toxic effects of combined exposure to microplastics and nanomaterials.","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"34 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143819989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"GO-SELEX-enhanced dual-recognition sensor for highly specific detection of azamethiphos","authors":"Lingjun Geng, Jingcheng Huang, Haowei Dong, Haifang Wang, Rui Xu, Zhiping Yu, Ibrahim A. Darwish, Yemin Guo, Xia Sun","doi":"10.1016/j.jhazmat.2025.138252","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2025.138252","url":null,"abstract":"Organophosphorus pesticides (OPs) have attracted attention due to their widespread application in agriculture and public health. Among them, azamethiphos (AZA) may pose risks to non-target organisms and human health through food chain accumulation. Therefore, establishing a highly sensitive and specific detection method of AZA is of great significance for ensuring food safety and ecological protection. In this study, based on graphene oxide-SELEX technology, an aptamer (Apt) with specific recognition for AZA (K_d=26.27±1.27<!-- --> <!-- -->nM) was screened for the first time. This aptamer was subsequently integrated with molecularly imprinted polymers to construct a dual-recognition electrochemical sensor, leveraging the complementary advantages of both recognition elements. This dual-recognition strategy enabled the synergistic enhancement of specific recognition ability, effectively reducing interference from non-target substances and improving sensor selectivity and accuracy. Additionally, a doping strategy was adopted to modify the electrode surface with AuNPs@SnS₂@ZnCo-MOF nanocomposites, improving electron transfer efficiency and providing abundant active sites, thereby significantly enhancing the electrochemical signal response. The sensor exhibited a wide detection range (1.00×10^-2-1.00×10^{4<!-- -->}ng/mL) and a low limit of detection (3.33×10^{-3<!-- -->}ng/mL), while also demonstrating excellent stability and specificity. In summary, this study developed a highly efficient, sensitive and selective electrochemical sensor, providing a novel strategy for the rapid detection of AZA and other organophosphorus pesticides, with broad application prospects in food safety and environmental monitoring.","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"116 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143819991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}