Journal of Hazardous Materials最新文献

{"title":"Abatement of antibiotics and resistance genes during catalytic ozonation enhanced sludge dewatering process: Synchronized in volume and hazardousness reduction","authors":"Tingting Xiao ,&nbsp;Renjie Chen ,&nbsp;Chen Cai ,&nbsp;Shijie Yuan ,&nbsp;Xiaohu Dai ,&nbsp;Bin Dong ,&nbsp;Zuxin Xu","doi":"10.1016/j.jhazmat.2023.132912","DOIUrl":"10.1016/j.jhazmat.2023.132912","url":null,"abstract":"<div><p>Based on the efficiency of the catalytic ozonation techniques (HDWS+O₃ and MnFe₂O₄ @SBC+O₃) in enhancing the sludge dewaterability, the effectiveness in synchronized abatement antibiotics and antibiotic resistance genes (ARGs) was conducted to determine. The results revealed that catalytic ozonation conditioning altered the distribution of target antibiotics (tetracycline (TC), oxytetracycline (OTC), norfloxacin (NOR), ofloxacin (OFL)) in the dewatered filtrate, the dewatered sludge cake and the extra-microcolony/cellular polymers (EMPS/ECPS) layers, achieving the redistribution from solid-phase adsorption to liquid-phase dissolution. The total degradation rate was over 90% for TC and OTC, 72–78% for NOR and OFL; the abatement efficiency of eleven ARGs reached 1.47–3.01 log and 1.64–3.59 log, respectively, and more than four eARGs were eliminated. The effective abatement of the absolute abundance of Mobile genetic elements (MGEs) (0.91–1.89 log) demonstrated that catalytic ozonation conditioning could also significantly inhibit horizontal gene transfer (HGT). The abundance of resistant bacteria was greatly reduced and the signal transduction of the typical ARGs host bacteria was inhibited. The highly reactive oxidation species (ROS) generated were responsible for the abatement of antibiotics and ARGs. These findings provided new insights into the sludge conditioning for ideal and synchronized reduction in volume and hazardousness by catalytic ozonation processes in sludge treatment.</p></div>","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"463 ","pages":"Article 132912"},"PeriodicalIF":13.6,"publicationDate":"2023-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71435639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Machine learning-based prediction of cadmium bioaccumulation capacity and associated analysis of driving factors in tobacco grown in Zunyi City, China","authors":"Zilun Gou ,&nbsp;Chengshuai Liu ,&nbsp;Meng Qi ,&nbsp;Wenhao Zhao ,&nbsp;Yi Sun ,&nbsp;Yajing Qu ,&nbsp;Jin Ma","doi":"10.1016/j.jhazmat.2023.132910","DOIUrl":"10.1016/j.jhazmat.2023.132910","url":null,"abstract":"<div><p>Tobacco grown in areas with high-geochemical backgrounds exhibits considerably different cadmium (Cd) bioaccumulation abilities due to regional disparities and environmental changes. However, the impact of key factors on the Cd bioaccumulation ability of tobacco grown in the karst regions with high selenium (Se) geochemical backgrounds is unclear. Herein, 365 paired rhizospheric soil-grown tobacco samples and 321 topsoil samples were collected from typical karst tobacco-growing soil in southwestern China and analyzed for Cd and Se. XGBoost was used to predict and evaluate the Cd bioaccumulation ability of tobacco and potential influencing factors. Results showed that regional geochemical characteristics, such as soil Cd and Se contents, soil type, and lithology, have the highest influence on the Cd bioaccumulation ability of tobacco, accounting for 46.5% of the overall variation. Moreover, soil Se contents in high-geochemical background areas considerably affect Cd bioaccumulation in tobacco, with a threshold for the mutual suppression effects of Cd and Se at a soil Se content of 0.8 mg/kg. According to the results of bivariate local indicators of spatial association analysis, tobacco cultivated in the central, northeast, and southeast regions of Zunyi City carries a lower risk of soil Cd contamination. This study provides new insights for managing tobacco cultivation in karst regions.</p></div>","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"463 ","pages":"Article 132910"},"PeriodicalIF":13.6,"publicationDate":"2023-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71436168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influencing factors and controlled release kinetics of H2O2 from PVP-coated calcium peroxide NPs for groundwater remediation","authors":"Jinsong Chen ,&nbsp;Hui Ma ,&nbsp;Haoyu Luo ,&nbsp;Hongbin Peng ,&nbsp;Qizhao Yan ,&nbsp;Shengyan Pu","doi":"10.1016/j.jhazmat.2023.132902","DOIUrl":"10.1016/j.jhazmat.2023.132902","url":null,"abstract":"<div><p><span>Calcium peroxide nanoparticles (nCP) as a versatile and safe solid source of hydrogen peroxide (H</span>₂O₂<span>) receive substantial attention from researchers as a potential groundwater remediation reagent. In this study, we synthesized polyvinylpyrrolidone-coated calcium peroxide nanoparticles (PVP@nCP-PVP) to control the release rate of H</span>₂O₂ and modulate pH fluctuation simultaneously. The PVP@nCP-PVP is fully characterized and the H₂O₂ releasing kinetics and mechanisms are investigated. The H₂O₂ release longevity of nCP increased with the concentration of controlled release material (CRM) encapsulated shell, while the production of H₂O₂ decreased inversely. The acidic condition is favorable for increasing H₂O₂ production by promoting the complex decomposition of nCP. The low temperature prolonged the longevity of nCP and suppressed the competitive side reaction for producing O₂. The release of H₂O₂ is consistent with zero-order reaction kinetics and the release of O₂<span> is consistent with first-order reaction kinetics. At last, different nCP composites were employed to construct a Fenton-like system for the degradation of nitrobenzene (NB). The degradation rate was raised from 57.6% by Fe (II)/nCP to 70.0% and 93.7% by Fe (II)/nCP-PVP and Fe (II)/PVP@nCP-PVP systems, respectively. These findings demonstrate that PVP@nCP-PVP has significant advantages in repairing organically contaminated groundwater.</span></p></div><div><h3>Environmental implication</h3><p><span>Groundwater contamination<span> poses a great threat to human health and ecosystems. In-situ chemical oxidation<span> (ISCO) is a widely used groundwater remediation technology. Calcium peroxide (CP) as solid hydrogen peroxide showed merits of low cost and high stability, but the further application was limited due to its violent chemical reaction and short longivity in groundwater . In this work, we prepared polyvinylpyrrolidone-coated controlled release nCP (PVP@nCP-PVP) for modulating the release of H</span></span></span>₂O₂. The investigation of H₂O₂ release kinetics under various environmental conditions enhances the understanding of the inherent relationship between the H₂O₂<span> release performance of controlled-release materials and contamination remediation. The feasibility using macromolecules<span> preparing controlled-release oxidizing agents was confirmed, providing a novel solution for groundwater contamination remediation.</span></span></p></div>","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"464 ","pages":"Article 132902"},"PeriodicalIF":13.6,"publicationDate":"2023-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71435740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physiological responses and molecular mechanism of Chlorella sorokiniana to surgical mask exudates in wastewater","authors":"Di Zhou ,&nbsp;Shuang Qiu ,&nbsp;Mengting Li,&nbsp;Wenju Shan,&nbsp;Zhipeng Chen,&nbsp;Zhengshuai Wu,&nbsp;Shijian Ge","doi":"10.1016/j.jhazmat.2023.132891","DOIUrl":"10.1016/j.jhazmat.2023.132891","url":null,"abstract":"<div><p>Microalgae-based bioremediation is likely to be challenged by the microplastics (MPs) in wastewater induced by the widely use of surgical masks (SMs) during COVID-19. However, such toxic impact was generally evaluated under high exposure concentrations of MPs, which was not in agreement with the actual wastewater environments. Therefore, this study investigated the microalgal cellular responses to the surgical mask exudates (SMEs) in wastewater and explored the underlying inhibitory mechanism from the molecular perspective. Specifically, 390 items/L SMEs (including 200 items/L MPs which was the actual MP level in wastewater) significantly inhibited nutrient uptake and photosynthetic activities interrupted peroxisome biogenesis and induced oxidative stress which destroyed the structure of cell membrane. Moreover, the SMEs exposure also affected carbon fixation pathways, suppressed ABC transporters while promoted oxidative phosphorylation processes for the ATP accumulation These comprehensive processes led to an 8.5% reduced microalgae growth and variations of cellular biocomponents including lipid, carbohydrate, and protein. The increased carotenoids and consumed unsaturated fatty acid were considered to alleviate the SMEs-induced stress, and the enhanced EPS secretion facilitated the homogeneous aggregation. These findings will enhance current understandings of the SMEs effects in wastewater on microalgae and further improve the practical relevance of microalgae wastewater bioremediation technology.</p></div>","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"463 ","pages":"Article 132891"},"PeriodicalIF":13.6,"publicationDate":"2023-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71436166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microplastics and chemical leachates from plastic pipes are associated with increased virulence and antimicrobial resistance potential of drinking water microbial communities","authors":"Xinxin Yang ,&nbsp;Yisu Zhou ,&nbsp;Rong Xia ,&nbsp;Jingqiu Liao ,&nbsp;Jingqing Liu ,&nbsp;Pingfeng Yu","doi":"10.1016/j.jhazmat.2023.132900","DOIUrl":"10.1016/j.jhazmat.2023.132900","url":null,"abstract":"<div><p>There is increasing recognition of the potential impacts of microplastics (MPs) on human health. As drinking water is the most direct route of human exposure to MPs, there is an urgent need to elucidate MPs source and fate in drinking water distribution system (DWDS). Here, we showed polypropylene random plastic pipes exposed to different water quality (chlorination and heating) and environmental (freeze-thaw) conditions accelerated MPs generation and chemical leaching. MPs showed various morphology and aggregation states, and chemical leaches exhibited distinct profiles due to different physicochemical treatments. Based on the physiological toxicity of leachates, oxidative stress level was negatively correlated with disinfection by-products in the leachates. Microbial network analysis demonstrated exposure to leachates (under three treatments) undermined microbial community stability and increased the relative abundance and dominance of pathogenic bacteria. Leachate physical and chemical properties (i.e., MPs abundance, hydrodynamic diameter, zeta potential, total organic carbon, dissolved ECs) exerted significant (<em>p</em> &lt; 0.05) effects on the functional genes related to virulence, antibiotic resistance and metabolic pathways. Notably, chlorination significantly increased correlations among pathogenic bacteria, virulence genes, and antibiotic resistance genes. Overall, this study advances the understanding of direct and indirect risks of these MPs released from plastic pipes in the DWDS.</p></div>","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"463 ","pages":"Article 132900"},"PeriodicalIF":13.6,"publicationDate":"2023-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71435644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification of novel NRF2-dependent genes as regulators of lead and arsenic toxicity in neural progenitor cells","authors":"Hae-Ryung Park ,&nbsp;David Azzara ,&nbsp;Ethan D. Cohen ,&nbsp;Steven R. Boomhower ,&nbsp;Avantika R. Diwadkar ,&nbsp;Blanca E. Himes ,&nbsp;Michael A. O'Reilly ,&nbsp;Quan Lu","doi":"10.1016/j.jhazmat.2023.132906","DOIUrl":"10.1016/j.jhazmat.2023.132906","url":null,"abstract":"<div><p>Lead (Pb) and arsenic (As) are prevalent metal contaminants in the environment. Exposures to these metals are associated with impaired neuronal functions and adverse effects on neurodevelopment in children. However, the molecular mechanisms by which Pb and As impair neuronal functions remain poorly understood. Here, we identified <em>F2RL2, TRIM16L</em>, and <em>PANX2</em> as novel targets of Nuclear factor erythroid 2-related factor 2 (NRF2)—the master transcriptional factor for the oxidative stress response—that are commonly upregulated with both Pb and As in human neural progenitor cells (NPCs). Using a ChIP (Chromatin immunoprecipitation)-qPCR assay, we showed that NRF2 directly binds to the promoter region of <em>F2RL2</em>, <em>TRIM16L</em>, and <em>PANX2</em> to regulate expression of these genes. We demonstrated that <em>F2RL2, PANX2</em>, and <em>TRIM16L</em> have differential effects on cell death, proliferation, and differentiation of NPCs in both the presence and absence of metal exposures, highlighting their roles in regulating NPC function. Furthermore, the analyses of the transcriptomic data on NPCs derived from autism spectrum disorder (ASD) patients revealed that dysregulation of <em>F2RL2</em>, <em>TRIM16L</em>, and PANX2 was associated with ASD genetic backgrounds and ASD risk genes. Our findings revealed that Pb and As induce a shared NRF2-dependent transcriptional response in NPCs and identified novel genes regulating NPC function. While further in vivo studies are warranted, this study provides a novel mechanism linking metal exposures to NPC function and identifies potential genes of interest in the context of neurodevelopment.</p></div>","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"463 ","pages":"Article 132906"},"PeriodicalIF":13.6,"publicationDate":"2023-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71435683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of oxygen-containing functional groups on the micromechanical behavior of biodegradable plastics and their formation of microplastics during aging","authors":"Wenyi Huang,&nbsp;Guoqiang Jiang,&nbsp;Lidan Xie,&nbsp;Xueqin Chen,&nbsp;Runzhe Zhang,&nbsp;Xiaoyun Fan","doi":"10.1016/j.jhazmat.2023.132911","DOIUrl":"10.1016/j.jhazmat.2023.132911","url":null,"abstract":"<div><p>Biodegradable plastics (BPs) are more prone to generate harmful microplastics (MPs) in a short time, which have always been ignored. Oxygenated functional group formation is considered to be a key indicator for assessing microplastic formation, while it is difficult to characterize at a very early stage. The micromechanical properties of the aging plastic during the formation of the MPs are highly influenced by the evolution of oxygen-containing functional groups, however, their relationship has rarely been revealed. Herein, we compared changes in the physicochemical properties of BPs and non-degradable plastic bags during aging in artificial seawater, soil, and air. The results showed that the oxidation of plastics in the air was the most significant, with the most prominent oxidation in BPs. The accumulation of carbonyl groups leads to a significant increase in the micromechanical properties and surface brittleness of the plastic, further exacerbating the formation of MPs. It was also verified by the FTIR, 2D-COS, AFM, and Raman spectroscopy analyses. Furthermore, the increased adhesion and roughness caused by oxygen-containing functional groups suggest that the environmental risks of BPs cannot be ignored. Our findings suggest that the testing of micromechanical properties can predicate the formation of the MPs at an early stage.</p></div>","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"463 ","pages":"Article 132911"},"PeriodicalIF":13.6,"publicationDate":"2023-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71435643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanism and synergistic effect of sulfadiazine (SDZ) and cadmium toxicity in spinach (Spinacia oleracea L.) and its alleviation through zinc fortification","authors":"Muhammad Nafees ,&nbsp;Adiba Khan Sehrish ,&nbsp;Sarah Owdah Alomrani ,&nbsp;Linlin Qiu ,&nbsp;Aasim Saeed ,&nbsp;Shoaib Ahmad ,&nbsp;Shafaqat Ali ,&nbsp;Hongyan Guo","doi":"10.1016/j.jhazmat.2023.132903","DOIUrl":"10.1016/j.jhazmat.2023.132903","url":null,"abstract":"<div><p><span>Cadmium (Cd) and antibiotic’s tendency to accumulate in edible plant parts and fertile land is a worldwide issue. The combined effect of antibiotics and heavy metals on crops was analyzed, but not mitigation of their toxicity. This study investigated the potential of zinc oxide nanoparticles (ZnO NPs) to alleviate the SDZ and Cd toxicity (alone/combined) to promote spinach growth. Results revealed that the ZnO 200</span> <!-->mg<!--> <!-->L^-1 spray decreased the malondialdehyde (MDA) 14%, hydrogen peroxide (H₂O₂<span><span>) 13%, and electrolyte leakage (EL) 7%, and increased the superoxide dismutase (SOD) 8%, peroxidase (POD) 25%, </span>catalase (CAT) 39% and ascorbate peroxidase (APX) 12% in spinach leaves under combined SDZ+Cd (25</span> <!-->mg Kg^-1+50<!--> <!-->mg Kg^-1) stress compared to ZnO 100<!--> <!-->mg<!--> <!-->L^-1 spray. Likewise, ZnO NPs 200<!--> <!-->mg<!--> <!-->L^-1 spray enhanced the zinc (Zn) 97%, iron (Fe) 86%, magnesium (Mg) 35%, manganese (Mn) 8%, and potassium (K) 23% in shoots under combined SDZ+Cd (25<!--> <!-->mg Kg^-1+50<!--> <!-->mg Kg^-1) stress compared to ZnO 100<!--> <!-->mg<!--> <!-->L^-1 spray. Further, ZnO 200<!--> <!-->mg<!--> <!-->L^-1 spray reduced Cd uptake in roots by 9% and shoots 15% under combined SDZ+Cd (25<!--> <!-->mg Kg^-1+50<!--> <!-->mg Kg^-1) stress compared to ZnO 100<!--> <!-->mg<!--> <!-->L^-1. Overall, ZnO NPs alleviated the SDZ and Cd toxicity and enhanced spinach growth in all treatments.</p></div>","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"464 ","pages":"Article 132903"},"PeriodicalIF":13.6,"publicationDate":"2023-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71435682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Indirect daylight oxidative degradation of polyethylene microplastics by a bio-waste modified TiO2-based material","authors":"Paola Amato ,&nbsp;Marzia Fantauzzi ,&nbsp;Filomena Sannino ,&nbsp;Ida Ritacco ,&nbsp;Giuseppe Santoriello ,&nbsp;Matteo Farnesi Camellone ,&nbsp;Claudio Imparato ,&nbsp;Aurelio Bifulco ,&nbsp;Giuseppe Vitiello ,&nbsp;Lucia Caporaso ,&nbsp;Antonella Rossi ,&nbsp;Antonio Aronne","doi":"10.1016/j.jhazmat.2023.132907","DOIUrl":"10.1016/j.jhazmat.2023.132907","url":null,"abstract":"<div><p>Microplastics are recognized as an emerging critical issue for the environment. Here an innovative chemical approach for the treatment of microplastics is proposed, based on an oxidative process that does not require any direct energy source (irradiation or heat). Linear low-density polyethylene (LLDPE) was selected as target commodity polymer, due to its widespread use, chemical inertness and inefficient recycling. This route is based on a hybrid material coupling titanium oxide with a bio-waste, rosin, mainly constituted by abietic acid, through a simple sol-gel synthesis procedure. The ligand-to-metal charge transfer complexes formed between rosin and Ti⁴⁺ allow the generation of reactive oxygen species without UV irradiation for its activation. In agreement with theorical calculations, superoxide radical ions are stabilized at ambient conditions on the surface of the hybrid TiO₂. Consequently, an impressive degradation of LLDPE is observed after 1 month exposure in a batch configuration under indirect daylight, as evidenced by the products revealed by gas chromatography-mass spectrometry analysis and by chemical and structural modifications of the polymer surface. In a context of waste exploitation, this innovative and sustainable approach represents a promising cost-effective strategy for the oxidative degradation of microplastics, without producing any toxic by-products.</p></div>","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"463 ","pages":"Article 132907"},"PeriodicalIF":13.6,"publicationDate":"2023-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S030438942302191X/pdfft?md5=5ba3ef2532182a61f57bbd2a92a986bb&pid=1-s2.0-S030438942302191X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71435642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phthalate metabolites in breast milk from mothers in Southern China: Occurrence, temporal trends, daily intake, and risk assessment","authors":"Yangyang Liu ,&nbsp;Minhua Xiao ,&nbsp;Kaiqin Huang ,&nbsp;Juntao Cui ,&nbsp;Hongli Liu ,&nbsp;Yingxin Yu ,&nbsp;Shengtao Ma ,&nbsp;Xihong Liu ,&nbsp;Meiqing Lin","doi":"10.1016/j.jhazmat.2023.132895","DOIUrl":"10.1016/j.jhazmat.2023.132895","url":null,"abstract":"<div><p><span>The extensive production and use of phthalates means that these compounds are now ubiquitous in the environment and various biota, which raises concerns about potential harmful health effects. In this study, phthalate metabolites (mPAEs) were measured in breast milk (</span><em>n</em> = 100) collected from mothers of southern China between 2014 − 2022. Of the nine target mPAEs, five were detected in all of the samples, including mono-methyl phthalate (MMP), mono-ethyl phthalate (MEP), mono-isobutyl phthalate (MiBP), mono-n-butyl phthalate (MnBP), and mono-(2-ethylhexyl) phthalate (MEHP). The total levels of mPAEs in breast milk ranged from 4.76 to 51.6 ng/mL, with MiBP and MnBP being the predominant isomers (MiBP + MnBP &gt; 48.3%). Increasing trends were observed in MMP (5.7%/year) and MEHP (7.1%/year) levels during the study period, while a decreasing trend were observed in MiBP (−6.6%/year); no clear temporal trends were found for the other metabolites and total mPAE levels. The results indicate that exposure to phthalates is still prevalent in southern China. Breastfeeding was found to contribute to estimated daily phthalate intakes of 0.383–6.95 μg/kg-bw/day, suggesting insignificant health risks to infants based on dietary exposure. However, the increasing exposure to MMP and MEHP calls for more research into the possible sources and potential risks.</p></div>","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"464 ","pages":"Article 132895"},"PeriodicalIF":13.6,"publicationDate":"2023-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71435641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}