Journal of Hazardous Materials最新文献

{"title":"Rapidly Dissolving Nanofiber Filters for Efficient Sampling and On-Site Detection of Airborne Bacteria","authors":"Kangqi Guo, Zhuolun Niu, Ziming Tu, Chun Chen","doi":"10.1016/j.jhazmat.2024.136850","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2024.136850","url":null,"abstract":"Exposure to airborne bacteria poses significant risks to human health, highlighting the need for on-site sampling and detection to facilitate control and early warning. Commercial dissolvable gelatin filters are efficient samplers but can only dissolve in warm water. This study developed nanofiber gelatin filters that can rapidly dissolve in room-temperature water, facilitating on-site sampling and detecting of airborne bacteria when combined with adenosine triphosphate (ATP) analysis. To enhance the dissolvability of gelatin filters, the electrospinning technique was employed to fabricate the nanofiber filters with a high surface area but low mass. The physical and biological sampling efficiencies of the developed filters were then measured using NaCl particles and airborne bacteria, respectively. The feasibility of on-site detection of airborne bacteria was demonstrated through laboratory and field tests. The results indicate that the developed filters dissolved rapidly in room-temperature water within 2<!-- --> <!-- -->s. The physical sampling efficiency was 98.96%, and the biological sampling efficiency was 90% higher than that of the standard Andersen impactor. Both laboratory and field experiments demonstrated that the proposed method could achieve on-site detection of airborne bacteria within 12<!-- --> <!-- -->min. This study simplifies the steps and reduces the time needed for on-site sampling and detection of airborne bacteria.","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"10 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142804592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Photochemical oxidation of Cr(III) to Cr(VI) in the presence of Fe(III): Influence of Fe(III) concentration and UV wavelength","authors":"Chun-Chien Yen, Kai-Yue Chen, M.M.M. Ahmed, Chien-Hui Syu, Yu-Ting Liu, Yi-Cheng Hsieh, Shih-Hao Jien, Yu-Min Tzou","doi":"10.1016/j.jhazmat.2024.136852","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2024.136852","url":null,"abstract":"The reduction of Cr(VI) to Cr(III) is key to lowering environmental toxicity and mobility, but the reverse process remains less understood. We investigated Cr(III) oxidation mechanisms across various pH levels and light wavelengths (185, 254, and 358<!-- --> <!-- -->nm) in the presence of Fe(III). At pH 3.0 under 358<!-- --> <!-- -->nm light, Cr(VI) production peaked at 11.65<!-- --> <!-- -->μM, driven by photo-reactive Fe(OH)²⁺ producing •OH radicals. While Fe(III) generally promotes Cr(III) oxidation, concentrations above 0.5<!-- --> <!-- -->mM inhibited the process. Oxidation was most intense under 185<!-- --> <!-- -->nm light, generating up to 217<!-- --> <!-- -->μM of Cr(VI), due to Fe(III) and water photolysis. At 254 and 358<!-- --> <!-- -->nm, •OH was solely produced by Fe(III) photolysis, where •OH oxidized Fe(II), which then reduced Cr(VI), slowing Cr(III) oxidation. Short-wavelength, high-energy light significantly enhances Cr(III) oxidation. Under such UV exposure in the atmosphere, Cr(III)-containing aerosols and particles may undergo harmful transformations, potentially entering ecosystems via acidic deposition and posing health risks.","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"10 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142804627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced TOC removal from paper mill wastewater using air dielectric barrier discharge plasma with persulfate sources: Mechanistic insights and continuous flow operation performance evaluation","authors":"Nurhaslina Abd Rahman, Reneesha Valiyaveettil Basheer, So Yeon Yoon, Choe Earn Choong, Young June Hong, Yeomin Yoon, Eun Ha Choi, Min Jang","doi":"10.1016/j.jhazmat.2024.136853","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2024.136853","url":null,"abstract":"This study investigates the removal of total organic carbon (TOC) from paper mill wastewater using air dielectric barrier discharge (DBD) plasma, combined with various persulfate sources, namely potassium peroxymonosulfate (PMS), potassium peroxydisulfate (PDS), and sodium persulfate (SPS). Mechanistic insights into the activation of plasma-PDS and -PMS were obtained through quenching experiments and electron spin resonance (ESR) techniques. The addition of persulfate to air DBD plasma increased TOC removal kinetics by approximately 1.7–3 times, with plasma-PDS exhibiting the highest synergistic factor of 3.14. The electric field from the plasma significantly enhanced radical production, with plasma-PDS outperforming plasma-PMS due to its higher generation of sulfate (SO₄^•−) and hydroxyl radicals (•OH), which are more effective at breaking down complex organic compounds in paper mill wastewater. In continuous-flow experiments, the plasma-PDS process with 10<!-- --> <!-- -->mM and a 90-minute retention time achieved a 94.5% TOC removal efficiency for actual paper mill wastewater over 8<!-- --> <!-- -->h operation, demonstrating its effectiveness and stability for extended treatment. Quenching experiments revealed that electrons play a key role in PDS activation, whereas ¹O₂ is crucial for PMS activation.","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"37 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142804630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Different contributions of crystalline and non-crystalline iron (hydr)oxides on the mobilization and thionation of diphenylarsinic acid in a flooded paddy soil","authors":"Meng Zhu, Yuan Li, Xiaobao Wei, Zhenqi Yan, Lu Yang, Ruyi Yang","doi":"10.1016/j.jhazmat.2024.136844","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2024.136844","url":null,"abstract":"Iron reduction impacts the mobilization and thionation of diphenylarsinic acid (DPAA) in soil, but the contribution of crystalline and non-crystalline iron remains unknown. A paddy soil deficient in non-crystalline iron (P-Fe_o), crystalline and non-crystalline iron (P-Fe_d) were incubated with sulfate-plus-lactate, and the results were compared with paddy soil (P) in our previous study. For treatments without ferrous sulfide (FeS) precipitation, the solution-to-solid ratio (<em>R</em>_L/S) of DPAA increased slightly and dramatically with iron reduction, respectively, for P-Fe_o and P, suggesting that the reduction of non-crystalline iron contributes more to DPAA mobilization than crystalline iron. The <em>R</em>_L/S was &gt; 0.667 and ≤ 0.667 for treatments without and with FeS, respectively, in P and P-Fe_o but not P-Fe_d, indicating that crystalline, rather than non-crystalline iron contributes more to DPAA sequestration through reduction and the subsequent FeS precipitation. The degree to which iron reduction facilitates DPAA mobilization or sequestration is likely determined by the composition and amount of iron in paddy soil, respectively. For treatments with FeS, the DPAA transformation rate was &lt; 44% and 74-86%, respectively, in P-Fe_o and P-Fe_d after 90 days, with the maximum value comparable to those without FeS in P after 30 days. This suggests that the crystalline iron in P-Fe_o and the residual, small amount of non-crystalline iron in P-Fe_d could reduce DPAA thionation by forming FeS, and such effect seems to depend on both the composition and the amount of iron in paddy soil. The results would deepen our understanding of the “As-Fe-S” interactions in soil.","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"28 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142797328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pesticide exposures and 10-year atherosclerotic cardiovascular disease risk: integrated epidemiological and bioinformatics analysis","authors":"Xueyan Wu, Dandan Wei, Yilin Zhou, Qingqing Cao, Guozhen Han, Erbao Han, Zhiwei Chen, Yao Guo, Wenqian Huo, Chongjian Wang, Shan Huang, Xin Zeng, Xinlu Wang, Zhenxing Mao","doi":"10.1016/j.jhazmat.2024.136835","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2024.136835","url":null,"abstract":"<h3>Background and Purpose</h3>Recent studies link pesticide exposures to cardiovascular disease risk factors. However, research on the combined effects of multiple pesticides on atherosclerotic cardiovascular disease (ASCVD) is limited, particularly in rural areas. Despite advances in toxicogenomics, the mechanisms underlying these effects remain unclear. This study aims to investigate the combined effects and mechanisms of pesticide exposures on ASCVD.<h3>Methods</h3>In the cross-sectional study section, 2291 participants were included. Variables were filtered using machine learning models, and associations between mixed exposure to multiple pesticides and ASCVD were explored using environmental mixed exposure models (weighted quartile sum (WQS) regression and quantile-based g-computation (QGC)). In the bioinformatics analysis section, the GEO, CTD, Malacards, and GeneCards databases were used to retrieve target genes for pesticide exposure and atherosclerotic diseases. Enrichment analysis was then performed to identify the biological pathways associated with these genes.<h3>Results</h3>Three machine models screened 34 pesticides. Single pesticide exposures, such as atrazine, oxadiazon, p,p'-DDE, α-BHC, β-BHC, fenitrothion, malathion, fenitrothion, cypermethrin, cypermethrin, and cypermethrin might increase the 10-year ASCVD risk (all P &lt; 0.05). Total mixed pesticide exposure was positively associated with 10-year ASCVD risk in both the QGC (3.223(2.196, 4.730)) and WQS models (4.642(3.070, 7.020)). Notably, there was a linear relationship between total_QGC (P__overal &lt; 0.001; P__nonlinearity = 0.864) and high 10-year ASCVD risk. In toxicogenomic bioinformatics analysis, we identified 112 potential atherosclerosis target genes affected by pesticide exposure. Pathway enrichment analysis suggests pesticide-induced atherosclerosis is linked to pathways such as metabolic pathways, lipid metabolism, MAPK, AMPK, FoxO signaling, apoptosis, fluid shear stress, endocrine resistance, TNF, and PI3K-Akt. Key genes were identified based on maximal clique centrality, including AKT1, TP53, IL6, BCL2, TNF, JUN, PTGS2, CASP3, MAPK3, and CASP9.<h3>Conclusion</h3>Individual and combined exposure to pesticides increased the 10-year ASCVD risk, especially in patients with T2DM. Mixed levels of pesticide exposure were linearly and positively associated with high 10-year ASCVD risk. The mechanism of atherogenesis by mixed pesticide exposure may involve pathways such as lipid metabolism, MAPK, AMPK, FoxO signaling, apoptosis, fluid shear stress, endocrine resistance, TNF, and PI3K-Akt.","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"234 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142797331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Co/SH-based MOFs incorporated nanofiltration membranes for efficient selenium uptake in water purification","authors":"Hansi Zhang, Qingzhi Liu, Peilei Zhou, Huiting Zhang, Lishan Xu, Xiaoxia Sun, Jia Xu","doi":"10.1016/j.jhazmat.2024.136836","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2024.136836","url":null,"abstract":"Metal-Organic Frameworks (MOFs) with high adsorption capacity have shown potential in removing pollutants from water, particularly the toxic selenium (Se). However, MOFs face two challenges in the application of Se removal, that is low removal efficiency and unfavorable powder properties for recovery. In this study, a Co-MOF-74-SH with dual active adsorption sites was synthesized and subsequently immobilized into membrane to fabricate a multi-functional nanofiltration (NF) membrane for efficient Se removal and salt-salt separation. The strong cooperative interaction between the dual active Co/S sites and Se resulted in an impressive Se removal efficiency of 94.1% for Co-MOF-74-SH. The adsorption energy and isosurface of electron density from DFT simulations showed the strong interaction between SeO₃^2- and S sites in Co-MOF-74-SH. NF membrane with Co-MOF-74-SH incorporation was fabricated. This membrane showed Se removal of ~99.6%, surpassing original membrane of ~74.4%, which was attributed to synergetic mechanism of adsorption and separation. Simultaneously, the membrane exhibited excellent separation performance, with divalent/monovalent salt selectivity up to more than 80 as well as high water permeance of 15.80<!-- --> <!-- -->L<!-- --> <!-- -->m^-2 h^-1 bar^-1. This work not only broadens efficient adsorbents for Se removal, but also paves the way for membrane material for water purification and wastewater resource utilization.","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"5 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142797292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Redox control in arsenic accumulation with organic matter derived from a varved lacustrine deposit in the Jurassic accretionary complexes","authors":"Yuma Masuki, Nagayoshi Katsuta, Sayuri Naito, Takuma Murakami, Ayako Umemura, Natsuko Fujita, Akihiro Matsubara, Masayo Minami, Masakazu Niwa, Hidekazu Yoshida, Satoru Kojima","doi":"10.1016/j.jhazmat.2024.136843","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2024.136843","url":null,"abstract":"Oxidation states and distribution of arsenic (As) in annually laminated (varved) lacustrine deposits were analyzed with a seasonal resolution. This deposit was formed in the mid-Holocene landslide-dammed paleolake in the upper reaches of the Ane River, central Japan and the paleolake watershed consists of the Jurassic accretionary complexes (Mino-Tamba belt) including sedimentary and igneous rocks. In the outcrop, centimeter-to-decimeter-scale silty clay layers alternating with laminated layers are well developed. Bulk concentrations of As in the two layers are 77 ± 27 μg/g on average and mostly occurred in the sulfide fraction (59% ± 9%). In the laminated layers, millimeter-scale organic matter (OM)-rich and siderite-rich layers were repeated, indicating deposition during the spring and autumn mixings and the summer stratification, respectively. The OM-rich layers distinctively contain As-rich layers concentrated at the margins of the siderite layers, while they have numerous As-rich hotspots coexisting with S and amorphous OM. Synchrotron-based micro-X-ray absorption near edge structure analysis demonstrated that the As-rich layers contain FeAs^–IS, As^IIS, and As^III₂S₃ at roughly the same levels, whereas FeAs^–IS is dominant for the As in hotspots. Based on the results, it is suggested that As accumulation in the varved deposit has been controlled by seasonal changes in OM supply and fluctuation in redox potential with post-depositional degradation of OM.","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"21 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142797332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Release of Volatile and Semi-volatile Organic Compounds from Polyvinyl Chloride Consumer Products under Solar Light: Implications for Indoor Air Quality","authors":"Rishikesh Bajagain, Pil-Gon Kim, Jung-Hwan Kwon, Yongseok Hong","doi":"10.1016/j.jhazmat.2024.136846","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2024.136846","url":null,"abstract":"This study investigated the effect of light on emission of various volatile and semi-volatile organic compounds (VOCs and SVOCs), from polyvinyl chloride (PVC) products using xenon lamp as a solar light simulator. The emission flux generally decreased over time, with the light-induced targeted ∑VOC flux being about 1.6-times higher than heat-induced flux during the initial 1-h exposure. The emission is less affected by air flow rate; however, it is increased with light intensity. In general, the ∑SVOC levels are 3–34 times higher than ∑VOC levels. Results indicate that the chemicals released from PVC might decompose into degradation products upon xenon-light irradiation, resulting in intermediate or low-molecular weight compounds. Furthermore, total daily intakes of targeted compounds for different age groups ranged 0.80–29.1<!-- --> <!-- -->µg/kg/day, while total hazard quotient and cancer risks posed by targeted VOCs ranged 0.02<img alt=\"single bond\" src=\"https://sdfestaticassets-us-east-1.sciencedirectassets.com/shared-assets/55/entities/sbnd.gif\" style=\"vertical-align:middle\"/>0.26; and 4.5×10⁻⁶–5.3×10⁻⁵, respectively, suggesting the probable risk. Besides, more than 700 peaks are recorded and characterized as non-targeted chemicals. Also, 65–80% of total number of chemical peaks emitted from PVC are attributed to VOCs, while that for SVOCs is 20–35%. The fraction of emitted VOC peaks to total peaks under heat and light exposure are found to be 65 and 80%, respectively. Therefore, indoor air quality can be deteriorated by the presence of PVC-related plastic products.","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"4 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142804628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identifying spatial drivers of soil heavy metal pollution risk integrating positive matrix factorization, machine learning, and multi-scale geographically weighted regression","authors":"Yujie Pan, Anmeng Sha, Wenjing Han, Chang Liu, Guowangchen Liu, Emily Welsch, Min Zeng, Shasha Xu, Yi Zhao, Shang Tian, Yiyi Li, Rui Deng, Xin Zhang, Huanhuan Shi, Yu Cui, Changsheng Huang, Hongxia Peng","doi":"10.1016/j.jhazmat.2024.136841","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2024.136841","url":null,"abstract":"Soil heavy metal (HMs) contamination poses significant ecological and health risks, yet the spatial drivers of HMs pollution remain poorly understood. This study integrates pollution risk assessment, positive matrix factorization, machine learning, and multi-scale geographically weighted regression to develop a framework for identifying the spatial drivers of soil HMs contamination risk in Yangtze River New City, China. Analysis of 7,152 samples revealed that although average HMs concentrations were below national standards, As, Cd, Cr, Cu, Hg, and Ni exceeded local background levels. Four key factors were identified as drivers of HMs contamination: natural sources (30.36%, influenced by soil type), mixed agricultural and transportation sources (29.56%, driven by cropland, aquaculture, and road density), human activities (12.68%, including population density and community activities), and industrial sources (27.42%, linked to factories and enterprises). Regional variations indicated that industrial activities, transportation, and human activities primarily influenced health risks, while agriculture and natural factors had a greater impact on ecological and environmental capacity risks. These findings underscore the importance of considering spatial heterogeneity in HMs pollution risk assessments and offer insights for developing targeted, region-specific policies to mitigate pollution risks of soil HMs.","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"39 2-3 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142797333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between air pollution and hospitalization for acute exacerbation of kidney failure: A nationwide time-stratified case-crossover study in China","authors":"Yalan Xiao, Cong Liu, Yichen Liu, Huihuan Luo, Yixiang Zhu, Lu Zhou, Ya Gao, Hongliang Zhang, Renjie Chen, Jianwei Xuan, Haidong Kan","doi":"10.1016/j.jhazmat.2024.136834","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2024.136834","url":null,"abstract":"<h3>Background</h3>Air pollution is a potential risk factor for kidney disease; however, the impact on kidney failure exacerbation is underexplored. This study assessed the short-term effects of air pollution on hospitalization for kidney failure exacerbation.<h3>Methods</h3>This nationwide, time-stratified, case-crossover study included 45,249 hospitalized patients with kidney failure from 153 hospitals in 20 Chinese provinces between 2013 and 2020. Air pollutant concentrations were obtained from the closest monitoring stations. Conditional logistic regression models were used to determine the associations between air pollutants and hospitalizations, with exposure-response curves fitted and stratified analyses conducted.<h3>Results</h3>For each interquartile range increase in pollutants (lag 0-2 days), there was a significant increase in kidney failure hospitalization: 3.46% for PM_2.5, 3.64% for PM_2.5-10, 7.88% for NO₂, and 4.37% for CO. No significant associations were observed for O₃ and SO₂. NO₂ had a linear exposure-response curve; PM_2.5 and PM_2.5-10 showed stronger effects at lower exposures, while CO’s effect increased at higher exposures. Furthermore, the impact was greater during the cold season.<h3>Conclusions</h3>This large-scale national study highlights the significant association between short-term exposure to PM_2.5, PM_2.5-10, NO₂, and CO and kidney failure exacerbation, providing novel insights into the combined effects of air pollution on kidney failure.","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"97 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142797291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}