Human Nutrition and Metabolism最新文献

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Effects of blenderized watermelon with the rind on satiety, postprandial glucose, and bowel movement, with sensory evaluation 带皮西瓜对饱腹感、餐后葡萄糖和排便的影响,并进行感官评价
Human Nutrition and Metabolism Pub Date : 2023-11-17 DOI: 10.1016/j.hnm.2023.200223
Trisha Molina, Liyue Zhang, Timothy Nishimura, Samantha Johansen, Kayla Buenaventura, Cassandra Wickstrom, Mee Young Hong
{"title":"Effects of blenderized watermelon with the rind on satiety, postprandial glucose, and bowel movement, with sensory evaluation","authors":"Trisha Molina,&nbsp;Liyue Zhang,&nbsp;Timothy Nishimura,&nbsp;Samantha Johansen,&nbsp;Kayla Buenaventura,&nbsp;Cassandra Wickstrom,&nbsp;Mee Young Hong","doi":"10.1016/j.hnm.2023.200223","DOIUrl":"https://doi.org/10.1016/j.hnm.2023.200223","url":null,"abstract":"<div><p>Watermelon is a well-liked fruit containing bioactive compounds and nutrients. Watermelon research on metabolic diseases often involves flesh, yet rind is less explored. This study examined effects of watermelon with rind on satiety, postprandial glucose, and bowel movement with a sensory evaluation in healthy adults. The study included 21 participants (age 23.6 ± 5.7y, BMI 22.6 ± 2.8 kg/m<sup>2</sup>) in a randomized double-blind crossover design. Participants consumed one cup of blenderized watermelon with and without rind separated by a one-week washout period. Sensory analysis included 23 semi-trained panelists to complete a triangle and a 7-point hedonic scale test. Results revealed significant increase in satiety for both trials over time, with more fullness for watermelon with rind (P &lt; 0.05). Rind stabilized glucose response compared to flesh (P &lt; 0.001). No bowel movement differences were found for either trial. Most sensory panelists (91 %) identified the sample of watermelon with rind in the triangle test (P &lt; 0.001). Higher ratings in color, consistency, smell, flavor, and sweetness for watermelon compared to watermelon with rind (P &lt; 0.01). Overall acceptance was significantly higher for watermelon compared to watermelon with rind (P &lt; 0.001). Findings suggest health-promoting effects of watermelon rind on satiety and glucose, but higher acceptance for watermelon flesh vs watermelon flesh with rind. Future studies should investigate potential benefits of rind in disease prevention and attenuation. Advancement in food technologies is also needed to increase palatability to promote rind consumption.</p></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"34 ","pages":"Article 200223"},"PeriodicalIF":0.0,"publicationDate":"2023-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666149723000403/pdfft?md5=d47ef725abfd14824fdf4597e8d26b5f&pid=1-s2.0-S2666149723000403-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138395504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of vitamin D with triglyceride-glucose index and cardiometabolic risk factors in subclinical hypothyroidism 亚临床甲状腺功能减退患者维生素D与甘油三酯-葡萄糖指数及心脏代谢危险因素的关系
Human Nutrition and Metabolism Pub Date : 2023-11-17 DOI: 10.1016/j.hnm.2023.200226
Roshan Kumar Mahat , Gautam Panda , Bibhu Prasad Nayak , Suchismita Panda
{"title":"Association of vitamin D with triglyceride-glucose index and cardiometabolic risk factors in subclinical hypothyroidism","authors":"Roshan Kumar Mahat ,&nbsp;Gautam Panda ,&nbsp;Bibhu Prasad Nayak ,&nbsp;Suchismita Panda","doi":"10.1016/j.hnm.2023.200226","DOIUrl":"https://doi.org/10.1016/j.hnm.2023.200226","url":null,"abstract":"<div><h3>Background</h3><p>The present study aimed to explore the association of vitamin D with triglyceride-glucose (TyG) index and cardiometabolic risk factors in subclinical hypothyroidism (SCH).</p></div><div><h3>Methods</h3><p>We recruited 75 individuals diagnosed with SCH and 75 healthy controls of both genders aged 20 to 65 years. Triiodothyronine (T<sub>3</sub>), thyroxine (T<sub>4</sub>), thyroid stimulating hormone (TSH) and 25-hydroxyvitamin D [25(OH)D] were measured using chemiluminescent immunoassay. Fasting plasma glucose and lipid profile were analyzed by standard methods. The TyG index was calculated as Ln [fasting triglycerides (mg/dL) × fasting glucose (mg/dL)]/2.</p></div><div><h3>Results</h3><p>There were significant decreases in 25(OH)D levels and changes in cardiometabolic risk factors among individuals with SCH compared to healthy controls. Additionally, there was a significant increase in the TyG index among the SCH group. Correlation and regression analysis revealed that 25(OH)D was significantly and negatively associated with TyG index, diastolic blood pressure (DBP), total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C) and very low-density lipoprotein cholesterol (VLDL-C). However, it was positively associated with high-density lipoprotein cholesterol (HDL-C).</p></div><div><h3>Conclusion</h3><p>Present study shows that SCH patients have lower vitamin D levels and higher TyG index, increasing cardiovascular disease risk. Screening and managing vitamin D deficiency is crucial in these subjects. In addition, TyG index could be used as an indicator for identifying vitamin D deficiency.</p></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"34 ","pages":"Article 200226"},"PeriodicalIF":0.0,"publicationDate":"2023-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666149723000439/pdfft?md5=78d631cef43ea2197269ff563da6de4c&pid=1-s2.0-S2666149723000439-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138430697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of nutrition education programme and controlled dietary modification on nutritional status in young male athletes 营养教育计划和控制饮食改变对年轻男运动员营养状况的影响
Human Nutrition and Metabolism Pub Date : 2023-11-14 DOI: 10.1016/j.hnm.2023.200230
Monalisa Debnath , Swapan Kumar Dey , Gouriprosad Datta , Amit Bandyopadhyay
{"title":"Impact of nutrition education programme and controlled dietary modification on nutritional status in young male athletes","authors":"Monalisa Debnath ,&nbsp;Swapan Kumar Dey ,&nbsp;Gouriprosad Datta ,&nbsp;Amit Bandyopadhyay","doi":"10.1016/j.hnm.2023.200230","DOIUrl":"https://doi.org/10.1016/j.hnm.2023.200230","url":null,"abstract":"<div><h3>Purpose</h3><p>The current study sought to assess the synergistic effects of an eight-week nutrition education program (NEP) and controlled dietary modification (CDM) on the nutrition knowledge (NK), nutrition practice (NP), and daily dietary intake of nutrition counselling group (NCG) versus ad-libitum group (ALG), as well as to identify the dietary factors predicting athletes' NP.</p></div><div><h3>Methods</h3><p>A total of 105 male players (14–18 years) from the sports disciplines-football, hockey, swimming, and athletics-were block randomized into the NCG and the ALG. The NCG underwent an 8-week nutritional intervention (NI) that included NEP and CDM, while ALG did not participate in the NI and followed ad-libitum dietary intake. Primary data on each subject's NK, NP, daily food intake, and anthropometric measurements were collected before and after the intervention period for paired and case-control analysis.</p></div><div><h3>Results</h3><p>A strong association has been depicted between players’ NK and NP. Daily intake of carbohydrate, protein, calcium, and dietary fibre could be referred to as the significant positive predictors of NP, while fat intake is the negative predictor. The synergistic implementation of NEP and CDM reduced the energy deficits among the NCGby significantly increasing their daily calorie intake to an average of 97%. Protein intake was significantly increased, thus meeting 88% of the recommendation, while the increase in carbohydrate intake was insignificant, meeting 89% of the standards post-NI. Further, the NCG showed significant increases in intake of minerals like calcium, phosphorus, iron, zinc, and selenium, while the ALG had substantial reductions. The former also exhibited significant rises in vitamin A, B9, B12, C, and E intakes. The most significant spikes in macro and micronutrient intake were observed in the footballers and hockey players, who were also the groups with the largest increases in NK and NP scores.</p></div><div><h3>Conclusion</h3><p>The equilibrium in macronutrient bifurcations and relative macronutrient and micronutrient intake post-intervention indicates the effectiveness of nutritional enactment through an 8-week controlled dietary modification and systematic nutrition education programme on the nutritional status of young athletes. Therefore, good nutrition knowledge may improve the dietary patterns and nutrition intake of athletes. Intervention studies should emphasize nutrition education, aiming for improved athletic performance.</p></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"34 ","pages":"Article 200230"},"PeriodicalIF":0.0,"publicationDate":"2023-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666149723000476/pdfft?md5=6a72254a208f399f31e89e210506ef4a&pid=1-s2.0-S2666149723000476-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134655740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Ramadan intermittent fasting on renal and liver function markers among healthy overweight and obese males: A prospective cohort study 斋月间歇禁食对健康超重和肥胖男性肾功能和肝功能指标的影响:一项前瞻性队列研究
Human Nutrition and Metabolism Pub Date : 2023-11-11 DOI: 10.1016/j.hnm.2023.200227
Ahmed Ismail Mohamed , Jama Mohamed , Mohamed Mussa Abdilahi , Barkhad Aden Abdek , Kalkidan Hassen Abate
{"title":"Effect of Ramadan intermittent fasting on renal and liver function markers among healthy overweight and obese males: A prospective cohort study","authors":"Ahmed Ismail Mohamed ,&nbsp;Jama Mohamed ,&nbsp;Mohamed Mussa Abdilahi ,&nbsp;Barkhad Aden Abdek ,&nbsp;Kalkidan Hassen Abate","doi":"10.1016/j.hnm.2023.200227","DOIUrl":"https://doi.org/10.1016/j.hnm.2023.200227","url":null,"abstract":"<div><p>Intermittent fasting (IF) has garnered attention for its potential to promote health and combat chronic diseases. This study focused on the effects of Ramadan fasting, a form of IF observed by Muslims, on renal and liver function markers, anthropometric measurements, and dietary intake in healthy overweight and obese men. The study involved 60 participants from Hargeisa, Somaliland, with an average age of 40.01 ± 7.99 years. Results revealed significant reductions in body weight (P ≤ 0.001), waist circumference (P ≤ 0.001), and body mass index (P ≤ 0.001) after Ramadan fasting. Urea levels decreased significantly (P = 0.003), and though creatinine levels showed a non-significant decrease, uric acid levels increased significantly within the normal range (P ≤ 0.001). Serum glutamate oxaloacetate transaminase (GOT) levels decreased significantly (P ≤ 0.001), while glutamate pyruvate transaminase (GPT) and alkaline phosphatase (ALP) levels remained stable. Dietary analysis indicated a significant decrease in total carbohydrates (P = 0.023), proteins (P = 0.006), and dietary cholesterol intake (P ≤ 0.001). These findings suggest that Ramadan fasting positively impacts anthropometric and renal-liver function markers in healthy overweight and obese men. The study contributes to the expanding understanding of intermittent fasting's potential health benefits, emphasizing the importance of considering Ramadan fasting as a preventive approach for metabolic disorders. Further research should explore long-term effects, mechanistic insights, and personalized clinical applications, while public health initiatives could educate individuals about safe and informed fasting practices.</p></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"34 ","pages":"Article 200227"},"PeriodicalIF":0.0,"publicationDate":"2023-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666149723000440/pdfft?md5=d38b6216cae702d507522f6b5a0075f3&pid=1-s2.0-S2666149723000440-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136572329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of a school-based intervention to manage overweight and obesity among adolescents in Seremban, Malaysia: A cluster randomized controlled trial 一项以学校为基础的干预措施在马来西亚塞伦班管理青少年超重和肥胖的有效性:一项随机对照试验
Human Nutrition and Metabolism Pub Date : 2023-11-11 DOI: 10.1016/j.hnm.2023.200229
Wai Kent Lai , Sherina Mohd Sidik , Lekhraj Rampal , Wan Ying Gan , Siti Irma Fadhilah Ismail
{"title":"Effectiveness of a school-based intervention to manage overweight and obesity among adolescents in Seremban, Malaysia: A cluster randomized controlled trial","authors":"Wai Kent Lai ,&nbsp;Sherina Mohd Sidik ,&nbsp;Lekhraj Rampal ,&nbsp;Wan Ying Gan ,&nbsp;Siti Irma Fadhilah Ismail","doi":"10.1016/j.hnm.2023.200229","DOIUrl":"https://doi.org/10.1016/j.hnm.2023.200229","url":null,"abstract":"<div><p>The aim of the study was to evaluate the effectiveness of a school-based intervention programme among overweight and obese adolescents in Seremban, Negeri Sembilan, Malaysia. A cluster randomised controlled trial was conducted to evaluate the effect of the intervention (n = 200) and compared with control group (n = 200). The intervention was developed based on social cognitive theory, conducted in a group based, five-session of face-to-face, bi-weekly for 10 weeks. The primary outcomes were body mass index (BMI) and BMI-for-age z-scores (BAZ), whereas the secondary outcomes were breakfast consumption, physical activity level, self-efficacy, and body satisfaction. T-tests and generalized linear mixed model analysis were used to examine the effectiveness of the intervention at baseline, immediate post-intervention, and 3-month post-intervention, while controlling for covariates. A significant intervention effect was found in reducing BMI and BAZ. BMI of the participants in the intervention group was reduced from 28.10 kg/m<sup>2</sup> to 27.93 kg/m<sup>2</sup>, and further decreased to 27.80 kg/m<sup>2</sup>, while BAZ was reduced from 2.19 to 2.12, and further decreased to 2.07, from baseline to immediate post-intervention, and 3-month follow-up, respectively. Furthermore, there was significant improvement in breakfast consumption frequency, physical activity scores, healthy eating and weight self-efficacy scores, perceived physical activity self-efficacy scores, and body discrepancy scores as compared with the control group. The integrated school-based intervention programme was effective in reducing BMI and BAZ among overweight and obese participants. The results suggested that this programme could be integrated as one of the regular school co-curricular programmes.</p></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"34 ","pages":"Article 200229"},"PeriodicalIF":0.0,"publicationDate":"2023-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666149723000464/pdfft?md5=f4db32caaa464218859196946a2f112b&pid=1-s2.0-S2666149723000464-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134832571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Visceral adipose index, lipid accumulation product, and selected cardiometabolic risk markers among postmenopausal Sudanese women: A cross-sectional study 绝经后苏丹妇女内脏脂肪指数、脂质积聚产物和选定的心脏代谢风险标志物:一项横断面研究
Human Nutrition and Metabolism Pub Date : 2023-10-11 DOI: 10.1016/j.hnm.2023.200222
Ahlam Badreldin El Shikieri , Abdelgadir Elmugadam , Ghada A. Elfadil
{"title":"Visceral adipose index, lipid accumulation product, and selected cardiometabolic risk markers among postmenopausal Sudanese women: A cross-sectional study","authors":"Ahlam Badreldin El Shikieri ,&nbsp;Abdelgadir Elmugadam ,&nbsp;Ghada A. Elfadil","doi":"10.1016/j.hnm.2023.200222","DOIUrl":"https://doi.org/10.1016/j.hnm.2023.200222","url":null,"abstract":"<div><h3>Background</h3><p>In Sub-Saharan African countries, data examining postmenopausal women's cardiometabolic risk (CMR) remains limited. Our study aimed to assess the visceral adiposity index (VAI) and lipid accumulation product (LAP), atherogenic index of plasma (AIP), and physical activity levels of postmenopausal women and determine their CMR.</p></div><div><h3>Methods</h3><p>A cross-sectional study included 224 postmenopausal women aged ≥47 years recruited from Khartoum State, Sudan. Weight, height, waist and hip circumferences were measured. Physical activity levels were determined using the Global Physical Activity Questionnaire version 2. Fasting blood samples (5 mL) were collected to determine the lipid profile. The VAI and LAP were calculated as indicators for visceral adiposity, whereas AIP was calculated as an indicator of CVD risk.</p></div><div><h3>Results</h3><p>The postmenopausal women's mean age was 62.4 ± 10.2 years. Women (29.2%; 54/185) were physically inactive, with most inactive women being &gt;64 years and having ≥5 CVD risk factors compared with the active and very active women with 3–4 CVD risk factors. Women had high total cholesterol (24.6%), triglycerides (26.6%), low-density lipoprotein cholesterol (14.3%), and low high-density lipoprotein cholesterol (61.2%) levels. Moreover, women (33.5%) had a high CVD risk. In multiple regression analyses, AIP increased significantly with VAI and BMI. The ROC analysis revealed that the highest and statistically significant AUC was recorded for VAI followed by LAP among postmenopausal women, suggesting their diagnostic significance for CVD risk.</p></div><div><h3>Conclusion</h3><p>VAI and LAP were closely associated with an increased risk of CVD in postmenopausal Sudanese women and were considered the best diagnostic performance.</p></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"34 ","pages":"Article 200222"},"PeriodicalIF":0.0,"publicationDate":"2023-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49783525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison between Amino Acid Profiling of Structural Proteins of earliest and recent omicron strain of SARS-CoV-2 and Nutritional Burden on COVID-19 patients 最早和最新的SARS-CoV-2奥密克戎毒株结构蛋白氨基酸谱与新冠肺炎患者营养负担的比较
Human Nutrition and Metabolism Pub Date : 2023-10-08 DOI: 10.1016/j.hnm.2023.200220
Vivek Ambade , Sonia Ambade , Vaibhav Sharma , Prasanna Sanas
{"title":"Comparison between Amino Acid Profiling of Structural Proteins of earliest and recent omicron strain of SARS-CoV-2 and Nutritional Burden on COVID-19 patients","authors":"Vivek Ambade ,&nbsp;Sonia Ambade ,&nbsp;Vaibhav Sharma ,&nbsp;Prasanna Sanas","doi":"10.1016/j.hnm.2023.200220","DOIUrl":"https://doi.org/10.1016/j.hnm.2023.200220","url":null,"abstract":"<div><p>Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has four structural proteins. Inside human host cell, it replicates, for which each requires all the structural proteins, and to generate these, entire requirement of amino acids is borne by the host. There is no data regarding amino acid profiling, variation in strains, and its actual burden on the human host. Profiling, with its therapeutic utility, was studied using genomics and proteomics of earliest Wuhan strain and was compared with the recent emerging heavily mutated variant of concern, Omicron. With each replicating SARS-CoV-2 consuming a considerable percentage of essential amino acids (EAAs), coronavirus infection causes huge burden of EAAs on the entire human body in generating billions and billions of SARS-CoV-2 and can cause depletion of body protein stores. The complete amino acid profiling of the structural proteins of SARS-CoV-2 can act as benchmark for designing the correct nutritional supplements for the management of nutritional burden on the patients with SARS-CoV-2 infection.</p></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"34 ","pages":"Article 200220"},"PeriodicalIF":0.0,"publicationDate":"2023-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49783524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nutrition therapy in critically ill patients with traumatic brain injury 危重颅脑损伤患者的营养治疗
Human Nutrition and Metabolism Pub Date : 2023-09-25 DOI: 10.1016/j.hnm.2023.200219
Shahmini Ganesh, Noor Airini Ibrahim
{"title":"Nutrition therapy in critically ill patients with traumatic brain injury","authors":"Shahmini Ganesh,&nbsp;Noor Airini Ibrahim","doi":"10.1016/j.hnm.2023.200219","DOIUrl":"https://doi.org/10.1016/j.hnm.2023.200219","url":null,"abstract":"<div><p>Road traffic collisions are the commonest cause of traumatic brain injury (TBI). Patients with brain injury may present with a wide range of symptoms depending on nature and types of injury. Generally, severity of TBI can be classified into mild, moderate and severe based on Glasgow Coma Scale (GCS). This scoring system objectively describes the extent of impaired consciousness. Score of 8 or below indicates severe TBI and will require admission to intensive care and mechanical ventilation. These patients experience significant metabolic changes as a result of excessive production of endogenous catabolic hormones following the injury. Nutritional requirements among these patients differ based on severity of trauma and phase of illness. Timely initiation of feed and addressing individualised nutritional needs can prevent malnutrition. Apart from that, nutrition plays a very important role in neuronal recovery and directly affects neuronal plasticity thus the prognosis. Early involvement of nutritional support as a part of comprehensive care is the key to recovery and better outcome. The aim of this review is to provide an overview of the current evidence-based nutrition therapy for patients with TBI in critical care settings. The review covers the energy and nutrient requirements, enteral and parenteral nutrition, and challenges associated with it.</p></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"34 ","pages":"Article 200219"},"PeriodicalIF":0.0,"publicationDate":"2023-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49783523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The association of vitamin C and vitamin D status on bone mineral density and VCAM-1 levels in female diabetic subjects: Is combined supplementation with vitamin C and vitamin D potentially more successful in improving bone health than supplementation with vitamin D alone? 维生素C和维生素D状态与女性糖尿病受试者骨密度和VCAM-1水平的关系:与单独补充维生素D相比,联合补充维生素C和D在改善骨骼健康方面是否更成功?
Human Nutrition and Metabolism Pub Date : 2023-09-25 DOI: 10.1016/j.hnm.2023.200221
Christopher M. Stevens, Kamal Bhusal, Steven N. Levine, Richa Dhawan, Sushil K. Jain
{"title":"The association of vitamin C and vitamin D status on bone mineral density and VCAM-1 levels in female diabetic subjects: Is combined supplementation with vitamin C and vitamin D potentially more successful in improving bone health than supplementation with vitamin D alone?","authors":"Christopher M. Stevens,&nbsp;Kamal Bhusal,&nbsp;Steven N. Levine,&nbsp;Richa Dhawan,&nbsp;Sushil K. Jain","doi":"10.1016/j.hnm.2023.200221","DOIUrl":"https://doi.org/10.1016/j.hnm.2023.200221","url":null,"abstract":"<div><p>Bone mineral density (BMD), which is used to assess bone health, is often diminished in chronic disease states, such as diabetes, which increases the risk of bone fracture. The circulating vitamin C and 25-hydroxy-vitamin D levels are commonly lower in diabetic patients. Vitamin D is implicated in bone formation, while vitamin C has been shown to inhibit osteoclastic activity. Vascular cell adhesion molecule-1 (VCAM-1) promotes osteoclastic activity and bone loss. This study investigated whether any association exists between vitamin C and vitamin D status and BMD and VCAM-1 levels in female diabetic subjects (n = 65). 25-hydroxy-vitamin D had no significant relationship with either BMD or VCAM-1 levels. However, vitamin C showed a significant positive association with BMD and a negative association with VCAM-1. This suggests that combined supplementation with vitamin D and vitamin C, rather than supplementation with vitamin D alone, could be a better strategy for the improvement of bone health and thus deserves further investigation.</p></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"34 ","pages":"Article 200221"},"PeriodicalIF":0.0,"publicationDate":"2023-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49783514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Caffeinated non-alcoholic beverages on the postpartum mental health related to the COVID-19 pandemic by a cross-sectional study in Argentina 阿根廷一项横断面研究显示含咖啡因非酒精饮料对新冠肺炎大流行相关产后心理健康的影响
Human Nutrition and Metabolism Pub Date : 2023-09-01 DOI: 10.1016/j.hnm.2023.200198
Agustín Ramiro Miranda , Mariela Valentina Cortez , Ana Veronica Scotta , Elio Andrés Soria
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