Human Nutrition and Metabolism最新文献

{"title":"Association between overweight/obesity perception, actual body weight and cardiometabolic risk among healthy Ghanaian adults","authors":"Abdul-Malik Bawah ,&nbsp;Annan Reginald A ,&nbsp;Haadi Abdul-Rahman","doi":"10.1016/j.hnm.2024.200253","DOIUrl":"https://doi.org/10.1016/j.hnm.2024.200253","url":null,"abstract":"<div><h3>Background</h3><p>The global rise in obesity, particularly among black Africans in developing nations experiencing nutritional transitions, underscores the importance of exploring Overweight/Obesity Perception (OP) as a crucial factor in maintaining an optimal body weight. Incorrect body image perception may impede efforts to achieve the desired body weight, leading to adverse outcomes related to Cardiometabolic Diseases (CMD). This cross-sectional study investigated the interplay between overweight/obesity perception, actual body weight, and CMD risk in a cohort of healthy Ghanaian adults.</p></div><div><h3>Methods</h3><p>A total of 302 apparently healthy adults, aged 25–60 years, with Dagomba ancestry, were recruited from three communities. Participants were screened based on age, ancestry, history of communicable and Non-Communicable Diseases (NCD), and use of antidiabetic, lipid-lowering, and antihypertensive drugs. Anthropometric assessments and blood sample collections for biochemical analysis were conducted. Body image perception was measured using the Stunkard Figure Rating Scale (SFRS). Data were analyzed using descriptive statistics, chi-square tests, correlation analysis, logistic regression, and multivariate analysis.</p></div><div><h3>Results</h3><p>Participants had a mean age of 38.28 ± 10.88, with 61.6% being women. While 47% accurately perceived their body weight, 53% had incorrect perceptions. Notably, 47.2% underestimated and 8.5% overestimated their weight status. Among overweight individuals, 33% underestimated and 9.4% overestimated their weight, whereas among the obese, 66.7% and 33.3% respectively had inaccurate perceptions. Gender, serum triglyceride levels, and waist circumference were significantly associated with weight perception. About 55% of overweight/obese participants and 62.1% with high waist circumference did not express a desire to lose weight. Multiple logistic regression revealed that both overweight (AOR = 6, 95% CI (1.8–20.2), p &lt; 0.05) and obesity (AOR = 20.5, 95% CI (5–84.9), p &lt; 0.05) significantly increased the odds of CMD.</p></div><div><h3>Conclusion</h3><p>The findings underscore the association between overweight/obesity and an elevated risk of CMD. This emphasizes the imperative for public health interventions aimed at promoting an ideal body weight and highlighting the impact of overweight/obesity on CMD risk factors.</p></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"36 ","pages":"Article 200253"},"PeriodicalIF":0.0,"publicationDate":"2024-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S266614972400015X/pdfft?md5=54e38d679a11bf894f3d4270b0d6e706&pid=1-s2.0-S266614972400015X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139936178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The higher dietary inflammation is associated with a higher burden of multimorbidity of cardio-metabolic and mental health disorders in an urbanizing community of southern India: A cross-sectional analysis for the APCAPS cohort","authors":"Hemant Mahajan ,&nbsp;Judith Lieber ,&nbsp;Poppy Alice Carson Mallinson ,&nbsp;Santhi Bhogadi ,&nbsp;Santosh Kumar Banjara ,&nbsp;Sanjay Kinra ,&nbsp;Bharati Kulkarni","doi":"10.1016/j.hnm.2024.200254","DOIUrl":"https://doi.org/10.1016/j.hnm.2024.200254","url":null,"abstract":"<div><h3>Background &amp; aims</h3><p>Habitual dietary pattern has been shown to be a major modulator of systemic inflammation and is considered a modifiable risk factor for cardio-metabolic diseases (CMDs) and mental health disorders. We examined whether dietary-inflammation is associated with the multimorbidity of CMDs and mental health disorders in urbanizing-villages in southern India. We hypothesized that the participants with higher dietary-inflammation would have a higher burden of multimorbidity.</p></div><div><h3>Materials &amp; methods</h3><p>We conducted a cross-sectional analysis of 5984 adults (53% male) participating in the Andhra Pradesh Children and Parents' Study. We assessed dietary-inflammation using dietary inflammatory index (DII®) based on intake of 27 micro- and macro-nutrients which were measured using a validated food-frequency-questionnaires. The CMDs and mental health disorders were assessed using standardized clinical procedures and validated questionnaires. ‘Multimorbidity’ was defined as a co-existence of one or more CMDs (hypertension, diabetes, myocardial infarction, heart failure, angina and stroke) and one or more mental health disorders (depression and anxiety). The association of multimorbidity with dietary-inflammation was examined using robust Poisson regression.</p></div><div><h3>Results</h3><p>The prevalence of multimorbidity was 3.5% and ∼75% of participants were consuming a pro-inflammatory diet (DII &gt;0.0). As compared to the 1st DII-quartile (least dietary-inflammatory group), the adjusted prevalence ratio (95% confidence interval) for the presence of multimorbidity was 1.46(0.87, 2.46) for 2nd, 1.75(1.05, 2.89) for 3rd, and 1.77(1.06, 2.96) for 4th DII-quartile (p-trend = 0.021). There was no evidence of an interaction between DII and sex on multimorbidity.</p></div><div><h3>Conclusions</h3><p>Dietary-inflammation had a positive linear association with the multimorbidity, which suggest that even modest reduction in dietary-inflammation may reduce the multimorbidity burden.</p></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"36 ","pages":"Article 200254"},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666149724000161/pdfft?md5=24a0ba1c16b7b0664ba7de179e3df368&pid=1-s2.0-S2666149724000161-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139907464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Increased dependency on dietary supplements for calcium, vitamin B1 and vitamin C intake during the COVID-19 pandemic among healthy adults: Data from the eighth Korea national health and nutrition examination survey (2019–2020)","authors":"Jung Min Cho","doi":"10.1016/j.hnm.2024.200252","DOIUrl":"10.1016/j.hnm.2024.200252","url":null,"abstract":"<div><h3>Objective</h3><p>This study aimed to assess the data of a healthy population at the Korean national level to explore the prevalence of dietary supplement (DS) use changes and the contribution of DSs to micronutrient intake during the pandemic.</p></div><div><h3>Research methods and procedures</h3><p>Data from the first (2019, before the COVID-19 pandemic) and second (2020, the year that the acute pandemic caused substantial life changes) years of the eighth Korea National Health and Nutrition Examination Survey (KNHANES) were investigated using a weighted complex sample design. Conversions (supplementation/dietary intake (S/D ratio), supplementation to total intake (StT), and supplementation to reference (StR)) were presented to investigate DS dependency and demonstrate that individuals’ nutrient intake derived from DSs increased.</p></div><div><h3>Results</h3><p>The total adult population was 4871 and 4421 in 2019 and 2020, respectively. Among healthy adults, 64.2% took DSs in 2020, 7.2% higher than that in 2019 (P &lt; 0.001). Among those aged 30–49 years, 70.2% used DSs in 2020, a 9.1% increase from 2019 (P = 0.015). The S/D ratio of vitamin C intake was 6.45 ± 0.95 in 2020, which was greater than that in 2019 (3.82 ± 0.47, P = 0.038). The StT of Ca intake was 7.79 ± 0.98% in 2020, which was greater than that in 2019 (4.89 ± 0.60%, P = 0.020). The StR of vitamin B₁ intake was greater in 2020 (505.01 ± 36.95%) than in 2019 (368.82 ± 29.55%, P = 0.004).</p></div><div><h3>Conclusion</h3><p>DS dependency greatly increased during the COVID-19 pandemic and was accompanied by increased DS consumption and decreased Ca, vitamin B₁, and vitamin C intake in the healthy Korean population.</p></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"36 ","pages":"Article 200252"},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666149724000148/pdfft?md5=c8888b8ee4c35971b4307b4fb775e9e8&pid=1-s2.0-S2666149724000148-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139823587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Iron/foliate utilization and associated factors among pregnant women attending antenatal care at public hospitals in Bench Sheko Zone, South West, Ethiopia","authors":"Zewditu Alelign,&nbsp;Olantu Mekonnen,&nbsp;Emebet Adugnaw","doi":"10.1016/j.hnm.2024.200245","DOIUrl":"https://doi.org/10.1016/j.hnm.2024.200245","url":null,"abstract":"<div><h3>Background</h3><p>Iron/foliate affects the lives of more than two billion people, accounting for over 30% of global population which is the highest in developing countries and about 18% of maternal mortality in low- and middle-income countries. Iron/foliate supplementation for pregnant mothers is the most cost-effective method of reducing iron deficiency, low birth weight, and neural tube defects among pregnant mothers and newborns in resource-limited countries like Ethiopia, so the purpose of this study has been to assess the iron/foliate utilization status of pregnant mothers and associated factors among pregnant mothers.</p></div><div><h3>Method</h3><p>The study have used institution-based cross-sectional design with systematic random sampling, binary and multiple logistic regression to identify significantly associated variables, and a single population proportion formula to determine the sample size.</p></div><div><h3>Result</h3><p>From the total of 318 participants only 32.1% of them utilized iron/foliate adequately. Marital status (AOR; 0.03 95%, CL (0.01–0.86), occupation (AOR; 11.12 95%, CL (1.95–69.05), gestation age when ANC visit started (AOR; 0.23 95%, CL (0.07–0.83), health education(AOR; 36.51 95%, CL (10.14–131.46), waiting time(AOR; 0.07 95%, CL (0.02–0.27) and knowledge (AOR; 0.17 95%, CL (0.05–0.57) were significantly associated variables with the outcome variable.</p></div><div><h3>Conclusion</h3><p>According to this study, 32.1 % utilized iron/foliate adequately, whereas the remaining 67.9 % did not yet. Moreover, this study identified major associated variables with iron/foliate utilization status, including marital status, occupation, gestation age when ANC visit started, health education, average wait time, and knowledge of mothers on anemia/iron.</p></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"36 ","pages":"Article 200245"},"PeriodicalIF":0.0,"publicationDate":"2024-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666149724000070/pdfft?md5=b81833ea755488ea2aef4c4f356687c5&pid=1-s2.0-S2666149724000070-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139737461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ketogenic diet in clinical practices","authors":"İbrahim Hakkı Çağıran ,&nbsp;Dursun Alper Yılmaz","doi":"10.1016/j.hnm.2024.200250","DOIUrl":"https://doi.org/10.1016/j.hnm.2024.200250","url":null,"abstract":"<div><p>Epilepsy is a medical condition characterized by seizures. While antiepileptic drugs can effectively control seizures in most epilepsy patients, there exists a subtype known as resistant epilepsy in which drugs prove ineffective in managing seizure activity. Furthermore, some patients experience undesirable side effects from these medications, leading to the discontinuation of antiepileptic drug use. In such situations and others like them, the ketogenic diet is recommended as an alternative treatment approach, one that does not rely on pharmacological interventions The fundamental rationale supporting the potential efficacy of the ketogenic diet in epilepsy treatment lies in the fact that, in certain circumstances such as fasting, ketone bodies are utilized as the primary energy source for neurons, as opposed to glucose. To facilitate the generation of ketone bodies while ensuring ease and flexibility of implementation, various types of ketogenic diets have been developed. The choice of ketogenic diet approach in the treatment of epilepsy can be tailored based on the individual tolerability of patients. This meta-analysis aims to consolidate the evidence regarding the impact of ketogenic diets on patients with epilepsy in clinical practice.</p></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"36 ","pages":"Article 200250"},"PeriodicalIF":0.0,"publicationDate":"2024-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666149724000124/pdfft?md5=51189cc400f96cde0c35fe3e67536baa&pid=1-s2.0-S2666149724000124-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139694172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of omega-3 fatty acid supplementation on serum myostatin, body composition, blood glucose, lipid profile and hs-CRP level in overweight men with coronary heart disease: A randomized double-blind placebo controlled clinical trial","authors":"Mohammad sharifzadeh ,&nbsp;Leila setayesh ,&nbsp;Mohammad Reza Emami ,&nbsp;Shirin Jafari Salim ,&nbsp;Mo hammad Hassan Javanbakht","doi":"10.1016/j.hnm.2024.200248","DOIUrl":"10.1016/j.hnm.2024.200248","url":null,"abstract":"<div><h3>Background</h3><p>Cardiovascular diseases, including heart cachexia, are considered as one of the most critical issues in health care that could be affected by several factors, such as myostatin whose critical role has been confirmed in the progress of heart cachexia and cardiac muscle dysfunction. This study was conducted to clarify the precise role of omega-3 polyunsaturated fatty acid (ω-3PUFA) on lipid profile, blood glucose, body composition, and serum level of myostatin in individuals with coronary artery disease (CAD).</p></div><div><h3>Materials and methods</h3><p>Forty-two adult males (aged 45–65 years) with CAD had been confirmed by angiography were randomly divided into two groups, group 1 received omega-3 (1200mg daily) and group 2 received placebo (paraffin) for 8 weeks. The serum level of myostatin was measured using an ELISA kit in the beginning and at the end of the intervention. Moreover, body composition and anthropometric measurements of the patients were also evaluated.</p></div><div><h3>Result</h3><p>A significant difference was observed in the myostatin level after 8weeks of intervention with omega3 supplement between omega3 and placebo group (p = 0.02).There was a significant difference in high-sensitivity C-reactive protein(hsCRP) concentration (p = 0.02) and low-density lipoprotein cholesterol (p = 0.01) between intervention group and control group at the end of the intervention. However, no statistically significant changes were seen in the body composition, anthropometric parameters, fasting insulin level, and fasting blood sugar within and between the groups.</p></div><div><h3>Conclusion</h3><p>Omega-3 oral supplementation may improve the status of CAD patients by decreasing the level of myostatin, LDL-C and hs-CRP.</p></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"36 ","pages":"Article 200248"},"PeriodicalIF":0.0,"publicationDate":"2024-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666149724000100/pdfft?md5=b1b07cf0644edfd49e35481703c1d327&pid=1-s2.0-S2666149724000100-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139634980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enrichment with citrus peels as a strategy for improving the health benefits and nutritional value of breakfast cereals: A review","authors":"Ayokunle Olubode Ademosun","doi":"10.1016/j.hnm.2024.200239","DOIUrl":"10.1016/j.hnm.2024.200239","url":null,"abstract":"<div><p>Breakfast cereals (BFCs) are a popular choice for breakfast and the BFC market is growing at an annual rate of 4.1 % and stands as a 70 billion dollar enterprise today. However, there are a number of questions raised about the medicinal properties of BFCs as they are processed foods lot of added refined sugars and reduced fibres especially when made from processed grains. Therefore, improving the medicinal values of BFCs will include minimizing the refined sugar content, increasing the fibre content and fortifying with natural bioactive compounds which possess medicinal properties. Citrus peels are rich in fibre and bioactive compounds, even though they are considered a waste in many countries. Incorporating citrus peels into BFCs without adversely affecting the sensory properties will enhance the medicinal properties of BFCs as the peels have a number of already established medicinal properties. Citrus peel-enriched BFCs could be a tool in Functional Nutrition as they will not only supply needed nutrients to start the day, but they will also be able to prevent and manage degenerative conditions through their ability to modulate other factors connected with diseases such as inflammation regulation, mood disorders and weight control.</p></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"36 ","pages":"Article 200239"},"PeriodicalIF":0.0,"publicationDate":"2024-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S266614972400001X/pdfft?md5=5b7a54a01895d5bbf202714ad0a936f5&pid=1-s2.0-S266614972400001X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139636080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Increased nutrition knowledge and adherence to the Mediterranean diet are associated with lower body mass index and better self-rated general health among university students","authors":"Fatima Zahra Elmskini ,&nbsp;Aichetou Bouh ,&nbsp;Asmae Labyad ,&nbsp;Nouriya Elghoulam ,&nbsp;Hind Iraqi ,&nbsp;Slimane Mehdad ,&nbsp;Aicha Madkour ,&nbsp;Abderrahmane Moufid ,&nbsp;Mustapha Aabi ,&nbsp;Saber Boutayeb ,&nbsp;Khalid Taghzouti ,&nbsp;Hassan Aguenaou ,&nbsp;Souad Benaich","doi":"10.1016/j.hnm.2024.200240","DOIUrl":"https://doi.org/10.1016/j.hnm.2024.200240","url":null,"abstract":"<div><h3>Background</h3><p>Nutrition knowledge and adherence to the Mediterranean diet (MedDiet) have been suggested to have beneficial effects on weight status and general health. The scarcity of assessment of these effects on large samples of university students is, however, observed.</p></div><div><h3>Objective</h3><p>To investigate the association of nutrition knowledge and adherence to the MedDiet with body mass index (BMI) and self-rated general health among university students.</p></div><div><h3>Methods</h3><p>This was a cross-sectional study among 1776 university students aged 21.34 ± 2.47 years. Nutrition knowledge and MedDiet adherence scores were assessed using validated questionnaires. Anthropometric measurements and general health were self-reported.</p></div><div><h3>Results</h3><p>The prevalence of overweight and obesity was 23.1% and 4.0%, respectively. Approximately 52% of students self-rated their general health as fair or poor. MedDiet adherence score was positively correlated with nutrition knowledge scores (<em>P</em> &lt; 0.001) and inversely associated with BMI (<em>P</em> &lt; 0.001). Non-overweight students had significantly higher nutrition knowledge scores and MedDiet adherence scores compared to overweight/obese peers. Similarly, non-smoking students had higher nutrition knowledge scores than their smoking counterparts (<em>P</em> = 0.017). Participants who self-rated their general health as fair or poor showed significantly lower nutrition knowledge and MedDiet adherence scores than other groups. Health science students had significantly lower consumption of fish, legumes, olive oil, unrefined whole grains, fruits, and vegetables compared to other students.</p></div><div><h3>Conclusions</h3><p>Elevated levels of nutrition knowledge and adherence to the MedDiet were associated with lower BMI and better self-rated general health. Urgent interventions are needed to promote nutrition knowledge and healthy eating behavior among university students.</p></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"35 ","pages":"Article 200240"},"PeriodicalIF":0.0,"publicationDate":"2024-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666149724000021/pdfft?md5=cbac8df217bf7869a44e79d506540cc1&pid=1-s2.0-S2666149724000021-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139549540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of short term citrulline malate supplementation on oxidative stress and muscle damage in trained soccer players","authors":"Mohammad Sadegh Mirenayat ,&nbsp;Mohammad Faramarzi ,&nbsp;Mohammad Reza Ghazvini ,&nbsp;Jahangir Karimian ,&nbsp;Amir Hadi ,&nbsp;Zahra Heidari ,&nbsp;Mohammad Hossein Rouhani ,&nbsp;Amirmansour Alavi Naeini","doi":"10.1016/j.hnm.2024.200242","DOIUrl":"10.1016/j.hnm.2024.200242","url":null,"abstract":"<div><p>There is some evidence that citrulline malate (CM) limits the deleterious effect of oxidative stress in athletes, but its effect on team sports like soccer is not clear. Thus, the current research is designed to investigate the effect of short-term CM supplementation on oxidative stress and muscle damage markers in trained soccer players. In this randomized double-blind controlled trial, 28 healthy, highly-trained male soccer players were selected and randomly assigned into 2 groups to take 6 g/day CM or placebo for 7 days. Blood samples were then taken in a resting-state at baseline and 24 h after the 7-day supplement intervention; and serum malondialdehyde (MDA), total antioxidant capacity (TAC), catalase (CAT), glutathione (GSH), superoxide dismutase (SOD), lactate dehydrogenase (LDH), creatine kinase (CK), and uric acid levels were measured. Compared to the baseline, CM significantly decreased serum uric acid levels (P = 0.03) and significantly increased serum LDH concentrations (P = 0.002). However, there were no significant changes in serum levels of MDA, CAT, GSH, TAC, SOD, LDH CK, and uric acid compared to the placebo group (P &gt; 0.05). It appears that short-term CM supplementation does not improve oxidative stress and muscle damage in soccer players. Further investigations should be conducted to fully understand the effects of CM on soccer players.</p></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"36 ","pages":"Article 200242"},"PeriodicalIF":0.0,"publicationDate":"2024-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666149724000045/pdfft?md5=f1224569fc5658c25a3d17fa334eb00c&pid=1-s2.0-S2666149724000045-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139538643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of micronutrients on the treatment of diabetes","authors":"Samer Younes","doi":"10.1016/j.hnm.2023.200238","DOIUrl":"10.1016/j.hnm.2023.200238","url":null,"abstract":"<div><p>In the last two decades, there has been a significant increase in the number of individuals worldwide who are affected by diabetes. This review article aims to explore the correlation between specific vitamins and diabetes. It has been observed that individuals with diabetes tend to have lower levels of certain antioxidant vitamins, namely A, C, and E. This decrease in vitamin levels is believed to be a consequence of the need to manage oxidative stress caused by issues with glucose metabolism. Additionally, retinol-binding protein plays a role in regulation and adipocytokine function. Diabetics also exhibit reduced levels of thiamine, pyridoxine, and biotin. Research has indicated that diabetes can hinder the absorption of various nutrients, including vitamins B9 and B12, necessitating frequent replenishment of these vitamins. Insufficient levels of vitamin D have been linked to an increased risk of developing diabetes and related complications such as cardiovascular disease. While some studies suggest that vitamin K supplementation may improve glucose metabolism, it remains uncertain whether it can prevent or repair oxidative damage. Excessive vitamin supplementation has been shown to have negative effects, as demonstrated by numerous studies. The review that follows will analyze the association between several nutrients, specifically vitamins A, D, C, B3, B6, B9, Zn, B12, E, B1/K, and iron, and the pathways implicated in diabetes, as well as their potential regulatory effects.</p></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"35 ","pages":"Article 200238"},"PeriodicalIF":0.0,"publicationDate":"2024-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666149723000555/pdfft?md5=318c2925d8256a06d635fb547edab21d&pid=1-s2.0-S2666149723000555-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139538208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}