Human Nutrition and Metabolism最新文献

{"title":"Advances in nutritional risk screening tools for hospitalized patients with type 2 diabetes mellitus","authors":"Rao Xin,&nbsp;Fan Lin,&nbsp;Guo Chaoqun,&nbsp;Zou Changlian,&nbsp;Chen Xiaoyan,&nbsp;He Ting,&nbsp;Wu Chuntao,&nbsp;Zhao Xia","doi":"10.1016/j.hnm.2025.200312","DOIUrl":"10.1016/j.hnm.2025.200312","url":null,"abstract":"<div><h3>Object</h3><div>With the intensification of the global aging population trend and changes in lifestyle, the prevalence of type 2 diabetes mellitus (T2DM) continues to rise, and it has become a major global public health problem. Malnutrition is an independent risk factor that affects the clinical outcomes, quality of life, and physical functions of inpatients with T2DM, and nutritional risk is the potential precursor state of malnutrition. Early nutritional risk screening and assessment for inpatients with T2DM is crucial for the timely initiation of adequate nutritional support. Through the precise identification of the nutritional risk and nutritional status of patients, their clinical development trajectory can be predicted, and the positive impact of nutritional management and treatment can be clarified. Currently, there are various nutritional risk screening and assessment tools for inpatients with T2DM, but each has its own advantages, disadvantages, and scope of application. Therefore, this article reviews the commonly used nutritional risk screening and assessment tools for inpatients with T2DM, compares the screening and assessment contents, advantages and disadvantages, and scope of application of different tools, in order to provide references for the early prevention and treatment of patients and the implementation of individualized and standardized nutritional management pathways.</div></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"40 ","pages":"Article 200312"},"PeriodicalIF":1.9,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143823316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Latest trends on interplay of autophagy, adipose tissue, and gut microbiota in obesity-related metabolic disorders","authors":"Claudette Butoyi ,&nbsp;Muhammad Asad Iqbal ,&nbsp;Isaac Duah Boateng","doi":"10.1016/j.hnm.2025.200313","DOIUrl":"10.1016/j.hnm.2025.200313","url":null,"abstract":"<div><h3>Purpose of review</h3><div>This review aims to synthesize current research on the intricate relationships among visceral obesity (VO), autophagy (Atg), gut microbiota, and adipose tissue dysfunction, all of which contribute significantly to insulin resistance (IR) and associated metabolic disorders. Specifically, it seeks to identify key mechanistic pathways and potential therapeutic targets.</div></div><div><h3>Findings</h3><div>Contemporary investigations have established VO as a principal etiological factor in diabetes, non-alcoholic fatty liver disease (NAFLD), and cardiovascular disease (CVD), accounting for a substantial proportion of global metabolic disease incidence. Notable discoveries include: (1) the nuanced role of Atg in adipose tissue homeostasis, wherein tissue-specific aberrations, such as diminished ATG5 expression in visceral adipose tissue, exacerbate IR. Conversely, pharmacologically induced Atg, exemplified by rapamycin administration, enhances insulin sensitivity by 15–25 % in rodent models. (2) Alterations in gut microbial composition, characterized by a 40 % decrease in Bacteroidetes and an increase in Firmicutes, correlate with elevated visceral adiposity and systemic inflammation. Fecal microbiota transplantation in human studies has demonstrated restoration of microbial diversity, resulting in a 12 % reduction in hepatic steatosis in NAFLD patients; (3) adipose tissue macrophages exhibit a pro-inflammatory phenotype, evidenced by a 2-3-fold elevation in TNF-α levels in VO, which precipitates metabolic dysfunction through Toll-like receptor 4 and nuclear factor kappa B signaling pathways.</div></div><div><h3>Conclusion</h3><div>The interactive network involving Atg, gut microbiota, and adipose tissue represents a pivotal axis in the development of metabolic diseases. While interventions targeting Atg and microbiota modulation demonstrate potential, inconsistent outcomes, such as the variable efficacy of probiotic therapies, underscore the context-dependent nature of these mechanisms. Existing therapeutic approaches, including lifestyle modifications, pharmacological interventions, and bariatric surgery, address adiposity but require more targeted approaches. Future research should prioritize elucidating tissue-specific Atg regulation and developing personalized microbiota-based therapies to manage the complex pathophysiology of obesity-related disorders effectively.</div></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"40 ","pages":"Article 200313"},"PeriodicalIF":1.9,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143776438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Resting metabolic rate (RMR) of recreational female CrossFit® practitioners: Agreement between indirect calorimetry and predictive equations and correlation between RMR ratio and metabolic hormone levels","authors":"Marcus V.L. Dos Santos Quaresma ,&nbsp;Caroline Soares Santos ,&nbsp;Bruno Becaro ,&nbsp;Leonardo Azevedo Alvares ,&nbsp;Raphael Einsfeld Simões Ferreira ,&nbsp;Ronaldo Vagner Thomatieli-Santos ,&nbsp;Fernanda Patti Nakamoto","doi":"10.1016/j.hnm.2025.200311","DOIUrl":"10.1016/j.hnm.2025.200311","url":null,"abstract":"<div><div>Resting metabolic rate ratio (RMR_ratio) is calculated dividing the RMR from indirect calorimetry (RMR_IC) by the RMR estimate by equations (RMR_e). RMR_ratio is a tool for energy suppression assessment and it can be useful in situations of low energy availability. To date, predictive equations have not been evaluated regarding their agreement with RMR of female CrossFit® practitioners. As such, we aimed to verify the agreement between RMR_IC and RMR_e and its correlation with metabolic hormones. This was a cross-sectional study with nonprobability sampling. Participants (healthy women aged 18–39 years, with at least 1 year of regular CrossFit® training experience) visited the laboratory once for blood collection and nutritional, body composition, and RMR assessment. RMR_IC was estimated using K5; COSMED®. We evaluated its agreement with the RMR estimated by several equations. Then, for each predictive equation, the RMR_ratio was calculated. We assessed triiodothyronine (TT₃), leptin, and insulin-like growth factor (IGF-1) levels. The Bland–Altman method was used to identify the agreement between the RMR_IC and the RMR_e. Thirty female recreational CrossFit® practitioners (33.11 ± 5.23 y) were assessed. The Cunningham (1980) equation was the one that most agreed with the RMR_IC. Still, RMR_IC did not differ when compared to TT₃ (p = 0.470), leptin (p = 0.848), and IGF-1 (p = 0.634) levels. Likewise, we found no differences when RMR_ratio was compared by the median and tertiles of hormones. In summary, our findings revealed that the RMR_e showed low agreement with the RMR_IC. Besides, the RMR_ratio did not differ according to the hormones TT₃, leptin, and IGF-1 of female recreational CrossFit® practitioners.</div></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"40 ","pages":"Article 200311"},"PeriodicalIF":1.9,"publicationDate":"2025-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143800660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapeutic potential of Medical Nutrition Therapy (MNT) in Non-Alcoholic Fatty Liver Disease (NAFLD)","authors":"Abdul-Malik Bawah ,&nbsp;Kasim Abdulai ,&nbsp;Priscilla Cecilia Akpene Amenya","doi":"10.1016/j.hnm.2025.200308","DOIUrl":"10.1016/j.hnm.2025.200308","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Background&lt;/h3&gt;&lt;div&gt;Non-alcoholic fatty liver disease (NAFLD) is a common liver disorder strongly associated with metabolic syndrome, obesity, and insulin resistance, and is a significant contributor to liver-related morbidity and mortality worldwide. Medical Nutrition Therapy (MNT), focusing on dietary changes that reduce hepatic fat, improve insulin sensitivity, and regulate metabolic markers, is increasingly recognized as a key therapeutic approach for NAFLD management.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Objective&lt;/h3&gt;&lt;div&gt;This study assessed the therapeutic potential of MNT in NAFLD patients, focusing on its effects on liver function, metabolic health, and inflammation. Additionally, it examined how educational level and occupation, as components of socioeconomic status, influence MNT effectiveness.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methodology&lt;/h3&gt;&lt;div&gt;A cohort of 200 NAFLD patients was recruited from Tamale Teaching Hospital, Central Hospital, Tamale West Hospital, and Dagbang Medical Centre and randomly assigned to either an MNT intervention group or a &lt;strong&gt;control group receiving standard care, which included general dietary recommendations without structured MNT, routine medical follow-up, and lifestyle advice from healthcare providers.&lt;/strong&gt; Over a 12-month period, patients in the intervention group received personalized MNT, emphasizing a balanced diet, low glycemic index foods, and limited saturated fat intake. Key clinical data, including liver function tests (ALT, AST, GGT), metabolic markers (BMI, weight, fasting glucose, lipid profile), and inflammatory markers (C-reactive protein [CRP], tumor necrosis factor-alpha [TNF-α]), were collected at baseline and after 12 months. Regression analysis with interaction terms assessed the impact of educational level and occupational type on MNT outcomes.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;The MNT intervention group showed significant improvements in liver function tests (ALT and AST decreased by 25 % on average, p &lt; 0.01) and metabolic markers (BMI reduced by 3 %, p &lt; 0.01). Inflammatory markers also improved, with CRP and TNF-α levels decreasing significantly compared to the control group (p &lt; 0.01 and p &lt; 0.05, respectively). &lt;strong&gt;In contrast, the control group exhibited only minimal changes in these parameters, with non-significant reductions in ALT, AST, BMI, and inflammatory markers (p &gt; 0.05), reinforcing the added benefit of structured MNT over general dietary advice.&lt;/strong&gt; Higher educational levels and occupations with greater health literacy were independently associated with enhanced outcomes, suggesting that these socio-demographic factors moderated MNT's effectiveness. &lt;strong&gt;Therefore, integrating MNT into NAFLD treatment guidelines, enhancing health provider training, expanding access, and prioritizing public education will improve outcomes and prevent disease progression.&lt;/strong&gt;&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusion&lt;/h3&gt;&lt;div&gt;MNT effectively manages and provides superior be","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"40 ","pages":"Article 200308"},"PeriodicalIF":1.9,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143760153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of metabolic syndrome on adiponectin, cardio-ankle vascular index, and cardiovascular risk in middle-aged obese men: A cross-sectional study","authors":"Thanutchaporn Nutmakul ,&nbsp;Lita Thamrongloessakun ,&nbsp;Jintana Sirivarasai ,&nbsp;Sirasa Ruangritchankul ,&nbsp;Wutarak Monsuwan","doi":"10.1016/j.hnm.2025.200309","DOIUrl":"10.1016/j.hnm.2025.200309","url":null,"abstract":"<div><div>This study aimed to determine the impact of metabolic syndrome (MetS) on cardiovascular disease (CVD) risk in obese men by assessing adiponectin levels, cardio-ankle vascular index (CAVI), and the 10-year risk of atherosclerotic cardiovascular disease using the Thai cardiovascular risk score (TCVRS), and evaluated whether CAVI and adiponectin could serve as predictors for CVD. Among 82 middle-aged obese men, 70.7 % had MetS, 56.1 % had hypoadiponectinemia, 20.7 % were classified as having a high CAVI (&gt;8), and 15.9 % were considered at high cardiovascular risk (TCVRS ≥20 %). Participants in the MetS group had a higher CVD risk, as evidenced by significantly higher TCVRS and lower adiponectin compared to the non-MetS group, though CAVI did not differ significantly. Among the components of MetS, high triglyceride and low HDL-cholesterol levels affected adiponectin levels, while high fasting plasma glucose levels impacted CAVI values, which was supported by Spearman correlation analysis. Additionally, CAVI positively correlated with TCVRS and was identified as an independent predictor of CVD risk in both the total and MetS groups. Conversely, adiponectin exhibited an inverse correlation and was an independent predictor in the non-MetS group. Importantly, subgroup analysis indicated that participants with higher CAVI had a greater CVD risk compared to those with normal CAVI levels. Notably, participants with high CAVI who did not have hypoadiponectinemia exhibited the highest TCVRS, with over half classified as being at high cardiovascular risk.</div></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"40 ","pages":"Article 200309"},"PeriodicalIF":1.9,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143654512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deciphering the role of dietary modifications and gut dysbiosis in Non-Alcoholic Fatty Liver Disease","authors":"Meenakshi Vachher ,&nbsp;Kohinoor Kaur ,&nbsp;Manisha Marothia ,&nbsp;Archana Burman ,&nbsp;Deepanjana ,&nbsp;Savita Bansal","doi":"10.1016/j.hnm.2025.200305","DOIUrl":"10.1016/j.hnm.2025.200305","url":null,"abstract":"<div><div>Non-alcoholic fatty liver disease (NAFLD) is emerging as a major health concern and economic burden worldwide. Approximately one-third of the total population is affected by NAFLD. The more aggressive form of NAFLD, non-alcoholic steatohepatitis (NASH) could progress to liver failure, fibrosis, cirrhosis, hepatocellular carcinoma and even death. NAFLD is multifactorial in origin and the gut microbiota dysregulation is one of the key features of NAFLD. Dietary alterations or nutritional interventions have a huge impact on gut microbiota composition and functions. An association between the type of diet, altered gut microbiota, and NAFLD is now being appreciated. The gut dysbiosis characterized by the changes in gut microbiota composition and its metabolites contribute to the development and progression of NAFLD through multiple mechanisms. The gut dysbiosis affects the intestinal permeability by generating endogenous ethanol, increased level of toxins such as lipopolysaccharides, and also influences the amino acid metabolism particularly tryptophan which activates the pro-inflammatory cytokines promoting hepatic inflammation. Altered microbial composition also disturbs the bile acids homeostasis which affects the energy balance and lipid metabolism through signaling via bile acid receptors. Therefore gut microbiota profiling in NAFLD patients may provide valuable information in predicting disease severity. Also, finding the key metabolites and markers of gut dysbiosis and their role in the pathogenesis of liver disease might prove helpful in designing novel and effective therapies for NAFLD. The present review succinctly summarizes gut dysbiosis triggered by various dietary factors especially macronutrients including proteins, fats and carbohydrates leading to the development and progression of NAFLD. We also address the gaps in the present studies as well as future prospects of manipulating gut microbiota for improved therapeutic and diagnostic applications in NAFLD.</div></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"40 ","pages":"Article 200305"},"PeriodicalIF":1.9,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143509729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Formula with real food ingredients for tube feeding in children with neuromuscular disorders (NMDs): A case series","authors":"Valeria Dipasquale,&nbsp;Rossella Morello,&nbsp;Claudio Romano","doi":"10.1016/j.hnm.2025.200306","DOIUrl":"10.1016/j.hnm.2025.200306","url":null,"abstract":"<div><div>The aim of this case series was to evaluate the tolerability, safety, and efficacy of an enteral formula containing food-derived ingredients for pediatric patients with neuromuscular disorders (NMDs). Children (1–17 years) with (i) a formally diagnosed NMD and (ii) exclusive enteral nutrition were enrolled. Patients received a nutritionally complete 1.2 kcal/mL enteral formula containing food-derived ingredients (peas, green beans, peaches, carrots, and chicken). Weight, body mass index (BMI), mid-upper-arm-circumference (MUAC) standard deviation (SD), and symptoms were assessed at the baseline (formula start; visit 1) and at 6 months (visit 2). Five NMD children with spinal muscular atrophy were included. Weight and BMI increased significantly after a mean of 2.5 months: weight −3.5 (V1) vs. −2.5 Z-score (V2) (p = 0.004) and BMI -3.8 (V1) vs. - 3 Z-score (V2) (p = 0.03). MUAC SD increased over the study period as well, even though the increase was not statistically significant (p = 0.231). All patients well tolerated the formula, and a relief from gastrointestinal symptoms was reported. The enteral formula containing food-derived ingredients may be a valid option in tube feeding management for children with NMDs. A small sample size and retrospective design limit the generalizability of findings. Further data (e.g., larger sample size, longer follow-up period, or different NMD subtypes) are needed.</div></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"40 ","pages":"Article 200306"},"PeriodicalIF":1.9,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143511628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of treatment outcome among severe acute malnutrition children admitted inpatient therapeutic feeding center in public health facilities of Jigjiga Town, Somali Region, Ethiopia","authors":"Mohamed Arab Abdilahi ,&nbsp;Shamsedin Mahdi Hassan ,&nbsp;Mohamed Omar Osman ,&nbsp;Muhumed Haji Abdi","doi":"10.1016/j.hnm.2025.200307","DOIUrl":"10.1016/j.hnm.2025.200307","url":null,"abstract":"<div><h3>Background</h3><div>Severe acute malnutrition (SAM) is a major public health problem in Ethiopia, with inconsistent and inconclusive treatment outcomes, particularly in the study area.</div></div><div><h3>Objective</h3><div>Therefore, this study aims to assess the predictors of outcome treatment among SAM under-five children admitted to stabilization centers in public health facilities in Jigjiga Town, Somali Region, Ethiopia, 2021.</div></div><div><h3>Methods</h3><div>A retrospective cohort study at Jigjiga Referral Hospital with 418 participants used checklist data entered EPI Data 3.1 and analyzed in SPSS 23, employing Kaplan-Meier and Cox regression to assess variables' association with recovery rate, including significant predictors (p &lt; 0.05) identified through bivariate and multivariate Cox models, and hazard ratios (HR) with 95 % CI.</div></div><div><h3>Results</h3><div>The recovery rate was 62.2 % with a median nutritional recovery time of 13 days. Vitamin A supplementation 1.4(AHR = 1.405 95 % CI: 1.058, 1.865), received plump nut 1.8 (AHR = 1.8, 95 % 1.250, 2.585) pneumonia 0.684 (AHR = 0.684, 95 % CI: 0.508, 0.921), history of diarrhea 0.614(AHR = 0.614, 95 % CI: 0.435, 0.866), correctly filled multi-chart 1.37 1.379 (AHR = 1.379, 95 % CI: 1.060, 1.795) were significantly associated the recovery rate.</div></div><div><h3>Conclusion</h3><div>The study found that the recovery rate remains low compared to the WHO Sphere standard benchmark and similar studies conducted in Ethiopia. To improve the recovery rate, interventions should prioritize ensuring accurate and complete chart documentation by healthcare providers and incorporating nutritional supplements such as Vitamin A.</div></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"40 ","pages":"Article 200307"},"PeriodicalIF":1.9,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143429690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of food components on cytochrome P450 expression and activity","authors":"Ruoyao Sang,&nbsp;Wenzhao Jiang,&nbsp;Cai Zhang,&nbsp;Runting Yin,&nbsp;Zhen Ouyang,&nbsp;Yuan Wei","doi":"10.1016/j.hnm.2025.200304","DOIUrl":"10.1016/j.hnm.2025.200304","url":null,"abstract":"<div><div>Cytochrome P450s (CYPs) are a family of enzymes within the hemoglobin superfamily that play a crucial role in drug metabolism. CYP activity and expression exhibit considerable individual variability. In addition to genetic factors, extrinsic influences, such as food, can affect their activity and/or expression, thereby impacting the efficacy and adverse effects of drugs metabolized by these enzymes. As food variety and diversity in dietary patterns increase, food has become an increasingly significant factor in drug metabolism. This review, summarizes the effects of various foods on the activity and expression of major CYP subtypes involved in drug metabolism, offering new insights into food-drug interactions and providing references for the safe clinical use of edible and medicinal plants.</div></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"40 ","pages":"Article 200304"},"PeriodicalIF":1.9,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143421863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding the role of green tea and matcha consumption in cardiovascular health, obesity, and diabetes: Insights from a Saudi Arabian population","authors":"Faisal Alsenani ,&nbsp;Nasser Alotaiq ,&nbsp;Doni Dermawan ,&nbsp;Nasr Eldin Elwali ,&nbsp;Mohammed Z. Nasrullah ,&nbsp;Rashed H. Almalki ,&nbsp;Nahar T. Alfarsi ,&nbsp;Alwaleed S. Almatrafi ,&nbsp;Muhannad S. Alsulami","doi":"10.1016/j.hnm.2025.200302","DOIUrl":"10.1016/j.hnm.2025.200302","url":null,"abstract":"<div><div>This study investigates the consumption patterns, health perceptions, and demographic correlates of green tea and matcha consumption in Saudi Arabia, focusing on their implications for cardiovascular health, obesity, and diabetes management. A survey was conducted among participants, focusing on demographics, consumption patterns, health perceptions, and lifestyle habits. Statistical analysis, including regression modeling, was employed to explore the relationships between perception, health outcomes, frequency, and duration of consumption. Participants perceived green tea and matcha as beneficial for weight management, cardiovascular health, and, to a lesser extent, diabetes control. While these perceptions align with existing literature on the health benefits of polyphenols and caffeine found in green tea and matcha, there were notable disparities in consumption patterns, with many participants reporting infrequent consumption. This discrepancy between public perception and scientific evidence underscores the need for balanced health communication strategies. Furthermore, the study highlights the importance of considering individual variations in response to these beverages, as evidenced by reported side effects like irregular heartbeats. Overall, this study contributes to understanding the role of green tea and matcha in promoting cardiovascular health, managing obesity, and potentially mitigating diabetes risk factors in the Saudi Arabian context.</div></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"40 ","pages":"Article 200302"},"PeriodicalIF":1.9,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143509727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}