Journal of Functional Foods最新文献

{"title":"Syringin as a novel therapeutic agent for renal cell carcinoma by targeting EGFR/PI3K/Akt pathway and enhancing sunitinib efficacy","authors":"Zixuan Chen ,&nbsp;Sheng Cheng ,&nbsp;An Xu ,&nbsp;Chengtao Han ,&nbsp;Xing Jia ,&nbsp;Min Liu","doi":"10.1016/j.jff.2024.106556","DOIUrl":"10.1016/j.jff.2024.106556","url":null,"abstract":"<div><div>Syringin, a natural bioactive compound extracted from <em>Acanthopanax senticosus</em>, has demonstrated potential therapeutic value in cancer treatment. However, its efficacy in treating renal cell carcinoma (RCC) remains unexplored. This study aims to investigate the therapeutic effects and underlying mechanisms of Syringin in RCC. In this study, network pharmacology, molecular docking validation, and bioinformatics were employed to predict the mechanisms by which Syringin affects RCC. In vitro experiments showed that Syringin inhibited RCC cell viability and reduced the IC50 of Sunitinib, enhancing its therapeutic effect. Syringin also inhibited RCC cell proliferation and migration and promoted apoptosis. The combination of Syringin and Sunitinib demonstrated an enhanced inhibitory effect. Western blot analysis confirmed that Syringin’s anti-RCC effects are mediated through the EGFR/PI3K/Akt pathway. In conclusion, our findings indicate that Syringin exhibits inhibitory effects on RCC cells and enhances their sensitivity to Sunitinib, offering a novel approach to exploring treatment strategies for Sunitinib-resistant RCC.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"123 ","pages":"Article 106556"},"PeriodicalIF":3.8,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142658017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potential blood pressure regulatory effect of low molecular weight α-chymotrypsin extract and its peptides from Stichopus japonicus: Peptide-ACE interaction study via in silico molecular docking","authors":"Hyo-Geun Lee ,&nbsp;D.P. Nagahawatta ,&nbsp;N.M. Liyanage ,&nbsp;Yu Ri Choe ,&nbsp;Jae-Young Oh ,&nbsp;Won-Kyo Jung ,&nbsp;Si-Hyeong Park ,&nbsp;You-Jin Jeon ,&nbsp;Hyun-Soo Kim","doi":"10.1016/j.jff.2024.106551","DOIUrl":"10.1016/j.jff.2024.106551","url":null,"abstract":"<div><div>Hypertension is a significant risk factor for cardiovascular disease and heart damage. <em>Stichopus japonicus</em> (<em>S. japonicus</em>) is a red sea cucumber with antioxidant and anti-hypertensive activities. However, its anti-hypertensive mechanism remains unclear. In this study, we evaluated the inhibitory effects of angiotensin-converting enzyme (ACE) of α-chymotrypsin-assisted hydrolysate of <em>S. japonicus</em> (α-chy) and its ultrafiltrate fractions (&gt;10 kDa [α-chy-I], 5–10 kDa [α-chy-II], and &lt;5 kDa [α-chy-III]). Low molecular α-chy-III exerted excellent ACE inhibitory and anti-hypertensive activities in spontaneously hypertensive rats (SHR). Moreover, α-chy-III significantly reduced the systolic and diastolic blood pressure by modulating the serum angiotensin and ACE levels. Histological analysis revealed that α-chy-III markedly protected the aorta, heart, and kidney tissues of SHR from hypertension-induced tissue damage.</div><div>Taken together, our findings highlight the potential of α-chy-III as a functional food ingredient for the treatment of hypertension and its comorbidities.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"123 ","pages":"Article 106551"},"PeriodicalIF":3.8,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142658043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oxyresveratrol from mulberry (Morus alba L.) ameliorates post-inflammatory hyperpigmentation in vitro by anti-melanogenesis, inhibiting melanosome transfer, and providing photoprotection","authors":"Hao Wang ,&nbsp;Xueping Chen ,&nbsp;Jing Li ,&nbsp;Zixiang Chen ,&nbsp;Aijing Zhou ,&nbsp;Li Ye","doi":"10.1016/j.jff.2024.106557","DOIUrl":"10.1016/j.jff.2024.106557","url":null,"abstract":"<div><div>Mulberry (<em>Morus alba</em> L.) twigs are a traditional Chinese medicine and edible agricultural by-product. Oxyresveratrol (OXY) is one of the natural resorcinol-type polyphenols obtained from mulberry twigs with anti-melanogenesis effects. This study aimed to investigate the ameliorative effects and mechanisms of OXY on post-inflammatory hyperpigmentation (PIH) <em>in vitro</em>. The results of DPPH radical scavenging and tyrosinase inhibition assays showed that OXY exhibited potent antioxidant and tyrosinase inhibitory activities. In human melanocytes, OXY significantly down-regulated protein expression related to melanin synthesis and transport. A molecular docking study suggested that OXY could inhibit these GTPases (RAB27A, RAC1, and CDC42) activities in melanosome transfer processes. Furthermore, OXY significantly reduced inflammatory factor secretion, promoted human β-defensin production, and up-regulated the expression of barrier proteins in UVB-induced human keratinocytes. This research indicated that the OXY from mulberry twigs has potential applications in ameliorating PIH through its antioxidant, anti-melanogenic, melanosome transport inhibition, anti-inflammatory, and photoprotective properties.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"122 ","pages":"Article 106557"},"PeriodicalIF":3.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142593825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development, basic information, classifications, pharmacological activities, and underlying mechanisms of medicine food homology: A review","authors":"Zhenguo Lv ,&nbsp;Lu Chen ,&nbsp;Huizi Ouyang ,&nbsp;Yameng Zhu ,&nbsp;Jinyue Ma ,&nbsp;Kaili Zhang ,&nbsp;Wenhan Lin ,&nbsp;Wenwen Li ,&nbsp;Zijing Zhang ,&nbsp;Jun He","doi":"10.1016/j.jff.2024.106552","DOIUrl":"10.1016/j.jff.2024.106552","url":null,"abstract":"<div><div>Medicine food homology is a special existence that combines the therapeutic effects of medicine and the nutritional value of food, making it possible for people to obtain health through daily diet. In this review, not only the concept, origin, and development of medicine food homology were introduced, but also the basic information of 102 medicine food homology substances authoritatively released by the Chinese Ministry of Health were summarized in detail and classified according to different methods. Moreover, the major pharmacological activities and underlying mechanisms of these 102 substances were concluded, and several creative ideas were proposed for the future development of new medicine food homology substances in the future. Collectively, this review provided a scientific basis and theoretical reference for the further exploration and utilization of new medicine food homology substances. Overall, the study of medicine food homology possesses a broad development prospect and great application value.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"122 ","pages":"Article 106552"},"PeriodicalIF":3.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142593823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gypenoside granules alleviate vascular smooth muscle cell phenotypic switching in atherosclerosis through impeding MAPK/KLF4 pathway","authors":"Zhi-Wei Zhao ,&nbsp;Wei Xu ,&nbsp;Ya-Ping Huang ,&nbsp;Yuan-Yuan Liu ,&nbsp;Yuan Teng ,&nbsp;Long Mu ,&nbsp;Zi-Yuan Wang ,&nbsp;Tian Li ,&nbsp;Zhao-Yang Gao ,&nbsp;Najihah Mohd Hashim ,&nbsp;Ke Pan ,&nbsp;Jian Zhang ,&nbsp;Lei Wang ,&nbsp;Zhi-Qi Yin","doi":"10.1016/j.jff.2024.106543","DOIUrl":"10.1016/j.jff.2024.106543","url":null,"abstract":"<div><div>Phenotypic switching of vascular smooth muscle cells (VSMCs) is crucial in atherosclerosis. Gypenoside granules, used clinically for hyperlipidemia, show significant atheroprotective effects, but their impact on VSMC phenotypic switching is unclear. This study evaluated the effects and mechanisms of gypenoside granules on VSMC phenotypic switching. Using ApoE^−/− mice on a high-fat diet, the study found that gypenoside granules reduced blood lipid levels, decreased necrotic core areas, increased fibrous cap thickness, and inhibited inflammation. In PDGF-BB-induced VSMCs, gypenoside granules suppressed phenotypic switching, proliferation, and migration by downregulating KLF4 expression. The beneficial effects were reversed by KLF4 overexpression. HPLC analysis identified ten key components in the granules. These findings suggest that gypenoside granules may alleviate atherosclerosis by modulating the MAPK/KLF4 pathway and could serve as an alternative treatment for the disease.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"122 ","pages":"Article 106543"},"PeriodicalIF":3.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142552054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Virgin coconut oil prevents airway remodeling and recovers tracheal relaxing reactivity by reducing transforming growth factor β expression on asthmatic guinea pig","authors":"Luiz Henrique César Vasconcelos ,&nbsp;Maria da Conceição Correia Silva ,&nbsp;Alana Cristina Costa ,&nbsp;Giuliana Amanda de Oliveira ,&nbsp;Iara Leão Luna de Souza ,&nbsp;Rubens da Silva Araújo ,&nbsp;Adriano Francisco Alves ,&nbsp;Fabiana de Andrade Cavalcante ,&nbsp;Bagnólia Araújo da Silva","doi":"10.1016/j.jff.2024.106544","DOIUrl":"10.1016/j.jff.2024.106544","url":null,"abstract":"<div><div>Asthma is a chronic inflammatory disease with many patients failing to respond appropriately to pharmacotherapy. Thus, virgin coconut oil (VCO) can be an alternative therapy. Guinea pigs were divided into control (Ctrl), chronic allergic lung inflammation (Asth), Asth treated with dexamethasone (Asth + dexa), and Asth supplemented with VCO (Asth + VCO4). The tested animals were sensitized and challenged with ovalbumin. Relaxation induced by arachidonic acid (AA) was impaired in Asth, and this reduction was prevented by VCO (p = 0.0004), indicating formation of relaxing prostanoids, or the decrease of cysteinyl-leukotrienes by VCO. Furthermore, a possible negative modulation of β receptors/BK_Ca pathway by TGF–β in Asth was prevented by VCO (p = 0.0073). Finally, in Asth, Masson’s trichrome staining revealed airway remodeling and immunohistochemistry showed increased TGF-β expression in the lungs of Asth (p &lt; 0.0001)), which was prevented by VCO and dexamethasone (p &lt; 0.0001), concluding VCO as a possible agent against asthma.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"122 ","pages":"Article 106544"},"PeriodicalIF":3.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142552059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lacticaseibacillus rhamnosus CCFM1060 Modulates gut microbiota and intestinal barrier Function: Alcoholic liver disease Mitigation through Nrf2/HO-1 and NF-κB Pathways","authors":"Ben Niu ,&nbsp;Lijuan Huang ,&nbsp;Xu Cheng ,&nbsp;Zhangming Pei ,&nbsp;Hongchao Wang ,&nbsp;Fengwei Tian ,&nbsp;Wenwei Lu","doi":"10.1016/j.jff.2024.106516","DOIUrl":"10.1016/j.jff.2024.106516","url":null,"abstract":"<div><div>Long-term and/or excessive ethanol intake can lead to alcoholic liver disease (ALD). Gut dysbiosis contributes to a critical role in the pathogenesis of ALD. Here, we explored the impact of viable and dead <em>Lacticaseibacillus rhamnosus</em> CCFM1060 on the gut microbiota of alcohol-treated mice. The findings indicated that CCFM1060 V and D (viable and dead) administration improved the gut microbiota composition. Specifically, CCFM1060 D restored the abundance of butyric acid-producing bacteria, Alistipes, Lachnospiraceae, and Ruminococcaceae in ethanol-induced mice; CCFM1060 V improved the abundance of <em>g_Dubsiela</em>, <em>g_Bifdobacterium</em>, <em>g_Ruminococcaceae_UCG_014_2</em>, the SCFA-producing bacteria which were decreased in alcoholic hepatitis. Furthermore, the interventions improved the microstructure of the ileum, including the villi and crypts. They reinforced the intestinal barrier by increasing the RNA and protein expression of claudin-1, occludin, and ZO-1 in the colon. Also, they have been shown to enhance the liver’s antioxidant function by suppressing the synthesis of MDA and boosting the concentrations of GSH and SOD through the Nrf2/HO-1 pathway. In addition, interventions can suppress mice’s levels of TNF-α and IL-6, IL-1β in serum, presumably via the TRL4/MyD88/NF-κB pathway. Together, these results suggest that CCFM1060 can modulate the gut microbiota structure, reinforce the intestinal barrier, improve intestinal homeostasis, enhance liver antioxidant capacity, and mitigate inflammation response, eventually protecting the liver from ethanol-induced injury.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"122 ","pages":"Article 106516"},"PeriodicalIF":3.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142578049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dietary supplementation with polyphenol-rich Salicornia ramosissima extracts: Assessing safety, efficacy, and impact on cardiovascular health biomarkers in healthy volunteers","authors":"Ana M. Nájar ,&nbsp;Soledad Pérez-Sánchez ,&nbsp;Carmen del Río ,&nbsp;Carmen Domínguez ,&nbsp;Cristina López Azcárate ,&nbsp;Reyes de Torres ,&nbsp;Marcel Lamana-Vallverdú ,&nbsp;Marina Romero-Bernal ,&nbsp;Ángela González-Díaz ,&nbsp;María de la Luz Cádiz-Gurrea ,&nbsp;Francisco Javier Leyva-Jiménez ,&nbsp;Álvaro Fernández-Ochoa ,&nbsp;Antonio León ,&nbsp;Joan Montaner","doi":"10.1016/j.jff.2024.106539","DOIUrl":"10.1016/j.jff.2024.106539","url":null,"abstract":"<div><div>The importance of diet in preventing non-communicable diseases is well established, with polyphenol consumption suggested to impact cardiovascular disease development. <em>Salicornia ramosissima synthesizes</em> high amounts of phytochemicals under environmental stress. In a randomized controlled clinical trial on 90 healthy volunteers, we evaluated the safety of supplementation with 1 g of polyphenol-rich <em>S. ramosissima</em> extracts from salt marshes and hydroponic sources over three months. No differences in adverse effects were observed between extract-treated and placebo subjects. Salicornia extract from marshes (SM) increased glomerular filtration rate and reduced LDL cholesterol. SM treatment also modulated plasma markers related to cardiovascular disease: MERTK, Gal-9, ADM, TF, PRSS27, HAOX1, IL-18, PAPPA, TNFRSF1A, TIE2 and FGF-21 proteins were downregulated while SRC levels were upregulated. Therefore, under the studied conditions of use, Salicornia extracts consumption is safe and SM induced biochemical and proteomic changes related to cardiovascular health.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"122 ","pages":"Article 106539"},"PeriodicalIF":3.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142552060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics of polysacchadride from Psoralea corylifolia in simulated gastrointestinal digestion and microbial fermentation","authors":"Zhenhua Yin ,&nbsp;Juanjuan Zhang ,&nbsp;Qingfeng Guo ,&nbsp;Jiale Zhi ,&nbsp;Xia Zhang ,&nbsp;Wei Zhang ,&nbsp;Lin Chen","doi":"10.1016/j.jff.2024.106549","DOIUrl":"10.1016/j.jff.2024.106549","url":null,"abstract":"<div><div><em>Psoralea corylifolia</em> polysaccharide (PPs) was the bioactive ingredient that conferred health benefits. In this study, simulated digestion and anaerobic fermentation models were employed to explore the digestion and fermentation characteristics of PPs and its effect on the intestinal microbiota. The results revealed that while the total and reducing sugar contents of PPs increased after simulated digestion, their molecular weight, monosaccharide composition, and overall structure remained unchanged, indicating that PPs was not degraded during digestion. On the other hand, during anaerobic fermentation, PPs was metabolized by intestinal microbiota, leading to the production of acetic acid and propionic acid, which subsequently reduced the pH of the fecal culture solution. Additionally, PPs modulated the composition of the intestinal flora, significantly decreasing the relative abundance of Proteobacteria while increasing the relative abundance of Bacteroidota and Firmicutes to varying degrees. This study highlighted the potential of PPs for development as functional foods and therapeutic agents.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"122 ","pages":"Article 106549"},"PeriodicalIF":3.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142593824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improvement of sleep quality and sub-health conditions through pasteurized fermented milk consumption: A human intervention study","authors":"Jia Zhao ,&nbsp;Hongliang Li ,&nbsp;Lai-Yu Kwok ,&nbsp;Xiuying Wu ,&nbsp;Hongxia Liu ,&nbsp;Xin Shen ,&nbsp;Feiyan Zhao ,&nbsp;Hao Qi ,&nbsp;Hairan Ma ,&nbsp;Zhihong Sun","doi":"10.1016/j.jff.2024.106562","DOIUrl":"10.1016/j.jff.2024.106562","url":null,"abstract":"<div><div>The sub-health state refers to a transitional condition between optimal health and disease, impacting physical, psychological, and social well-being. In this 42-day human intervention trial, we investigated the effects of two pasteurized fermented milks on sub-health symptoms. These pasteurized fermented milks shared the same starter culture and probiotic strains (<em>Lacticaseibacillus paracasei</em> PC-01, <em>Lactiplantibacillus plantarun</em> Lp-6, <em>Lactobacillus helveticus</em> H9, and <em>Bifidobacterium animalis</em> subsp. <em>lactis</em> Probio-M8), differing only in the presence of inulin. Qualified subjects were randomly assigned to the probiotic group (received milk without inulin; n = 49 or synbiotic group (received milk with inulin; n = 51). Outcome measures included Sub-Health Measurement Scale (SHMS) and Pittsburgh Sleep Quality Index (PSQI) scores, fecal metagenomes, metabolomes, and short-chain fatty acids, and serum neurotransmitter levels at baseline, after a 4-week intervention (day 28), and a 2-week-follow-up period (day 42). Our results showed that both pasteurized fermented milks improved sleep quality and alleviated sub-health symptoms, with no significant added benefit from inulin. Fecal metagenome analysis revealed post-interventional changes in gut microbial composition, including increased <em>Bifidobacterium longum</em> and decreased potentially pro-inflammatory bacteria (<em>Blautia</em> sp. and <em>Dorea</em> sp.). Changes in <em>Blautia</em> sp. and <em>B. longum</em> correlated significantly with SHMS and PSQI scores, respectively. Fecal and serum metabolite analysis showed post-interventional modulation of fecal short-chain fatty acids, anti-inflammatory bioactive metabolites, and serum neurotransmitters such as gamma-aminobutyric and serotonin hydrochloride. In conclusion, pasteurized fermented milk intake alleviated sub-health symptoms, affected the gut microbiome, metabolome, and serum metabolites. These findings highlight the potential of pasteurized fermented milk for mitigating sub-health conditions.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"122 ","pages":"Article 106562"},"PeriodicalIF":3.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142656406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}