Journal of Functional Foods最新文献_第5页

Effect of Clostridium butyricum and Bacillus coagulans on fecal and serum metabolic profiles in Helicobacter pylori-infected mice 丁酸梭菌和凝固芽孢杆菌对幽门螺杆菌感染小鼠粪便和血清代谢谱的影响

IF 3.8 2区农林科学

Journal of Functional Foods Pub Date : 2025-06-09 DOI: 10.1016/j.jff.2025.106938

Zhaobo Guan , Chunqi Feng , Pengyan Jia , Ya Yan , Juan Xu , Jingmin Zhang , Niuniu Bai , Weihong Chen , Weiqi Gao

{"title":"Effect of Clostridium butyricum and Bacillus coagulans on fecal and serum metabolic profiles in Helicobacter pylori-infected mice","authors":"Zhaobo Guan , Chunqi Feng , Pengyan Jia , Ya Yan , Juan Xu , Jingmin Zhang , Niuniu Bai , Weihong Chen , Weiqi Gao","doi":"10.1016/j.jff.2025.106938","DOIUrl":"10.1016/j.jff.2025.106938","url":null,"abstract":"<div><div>This study aims to explore the potential mechanism of <em>H. pylori</em> eradication by <em>Clostridium butyricum</em> and <em>Bacillus coagulans</em> through metabolomics. A mouse model of <em>H. pylori</em> infection was established by gavage of <em>H. pylori</em> solution into mice. Mice of the probiotic treatment group were given probiotics suspension. Then, the mouse feces and serum of all mice were collected for metabolomics analysis. The eradication rate of probiotics was 62.5 %, and it significantly altered the metabolic profiles of feces and serum in <em>H. pylori</em>-infected mice. Probiotics reversed 25 fecal and 18 serum metabolites. These metabolites are involved in the metabolic pathways related to linoleic acid metabolism, primary bile acid biosynthesis, arachidonic acid metabolism and lipid metabolism. This study demonstrated that two specific probiotics exhibited a significant capacity to partially eradicate <em>H. pylori</em>. Furthermore, we have provided preliminary insights into the eradication efficacy and underlying mechanisms of two probiotics against <em>H. pylori</em>.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"130 ","pages":"Article 106938"},"PeriodicalIF":3.8,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144239956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Riboflavin as a circadian modulator mitigates D-galactose-induced muscle senescence via oxidative stress and mitochondrial regulation in C2C12 cells 在C2C12细胞中，核黄素作为昼夜节律调节剂通过氧化应激和线粒体调节减轻d -半乳糖诱导的肌肉衰老

IF 3.8 2区农林科学

Journal of Functional Foods Pub Date : 2025-06-08 DOI: 10.1016/j.jff.2025.106924

Suhyeon Lee , Yumin Sim , Minkyeong Lee , Yoonha Choi , Ji Ye Lim , Je-Hyuk Lee , Eunju Kim

{"title":"Riboflavin as a circadian modulator mitigates D-galactose-induced muscle senescence via oxidative stress and mitochondrial regulation in C2C12 cells","authors":"Suhyeon Lee , Yumin Sim , Minkyeong Lee , Yoonha Choi , Ji Ye Lim , Je-Hyuk Lee , Eunju Kim","doi":"10.1016/j.jff.2025.106924","DOIUrl":"10.1016/j.jff.2025.106924","url":null,"abstract":"<div><div>Skeletal muscle aging is characterized by impaired myogenic differentiation, mitochondrial dysfunction, and circadian rhythm disruption, which contribute to sarcopenia and muscle atrophy. This study investigated the effects of riboflavin, a precursor of FAD and FMN, on circadian rhythm regulation, a crucial cofactor in mitochondrial redox metabolism, and mitochondrial function in the D-galactose-induced aging C2C12. D-galactose treatment impaired myotube formation, whereas Ribo 20 μM restored myotube formation and myotube width. Ribo restored the circadian oscillations of differentiation-related genes and core clock genes that were reduced by D-galactose. Ribo alleviated oxidative stress by regulating ROS, MDA, catalase, and GPx levels. Ribo improved mitochondrial function by increasing ATP production and mitochondrial membrane potential. Notably, Ribo restored ATP5A rhythmicity, highlighting its role in the circadian regulation of mitochondrial function. Riboflavin is a promising candidate for age-related muscle decline, as it restores myogenic differentiation, reduces oxidative stress, and supports mitochondrial function, preserving circadian homeostasis.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"130 ","pages":"Article 106924"},"PeriodicalIF":3.8,"publicationDate":"2025-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144239957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Degradation of rutin and genistein and the effect on human bacterial fecal populations of obese and non-obese 芦丁和染料木素的降解及其对肥胖和非肥胖人群粪便细菌群的影响

IF 3.8 2区农林科学

Journal of Functional Foods Pub Date : 2025-06-07 DOI: 10.1016/j.jff.2025.106930

Julia Jensen-Kroll , Tobias Demetrowitsch , Sabrina Sprotte , Fynn Brix , Alexia Beckmann , Kristina Schlicht , Erik Brinks , Matthias Laudes , Silvio Waschina , Charles M.A.P. Franz , Karin Schwarz

{"title":"Degradation of rutin and genistein and the effect on human bacterial fecal populations of obese and non-obese","authors":"Julia Jensen-Kroll , Tobias Demetrowitsch , Sabrina Sprotte , Fynn Brix , Alexia Beckmann , Kristina Schlicht , Erik Brinks , Matthias Laudes , Silvio Waschina , Charles M.A.P. Franz , Karin Schwarz","doi":"10.1016/j.jff.2025.106930","DOIUrl":"10.1016/j.jff.2025.106930","url":null,"abstract":"<div><div>This study re-evaluates the microbial degradation of rutin and genistein, emphasizing health-related metabotypes and novel degradation and transformation products of these compounds. In silico predictions and calculations were made to determine the molecular formulae of metabolites derived from precursor molecules by methylation, sulfation, and dehydroxylation. To validate these, anaerobic, ex vivo experiments were conducted with pooled fecal samples of obese and non-obese test persons (<em>n</em> = 7 per group) over 48 h, followed by 16S rRNA gene sequencing and semi-targeted, high-resolution mass spectrometry analysis. We identified 46 rutin and 23 genistein metabolites, including novel methylated and sulfated derivatives. Microbial analysis revealed that the plant compounds influenced 34 bacterial families and 83 genera. Rutin inhibited obesity-associated genera while promoting butyrate-producing bacteria in BMI >40 samples, but reduced health-associated bifidobacteria and increased enterobacteria. Both compounds stimulated <em>Eggerthella.</em> These findings highlight significant microbial and metabolic shifts induced by plant-derived compounds, suggesting potential health implications.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"130 ","pages":"Article 106930"},"PeriodicalIF":3.8,"publicationDate":"2025-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144231651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identification and characterization of antihypertensive peptides from edible Grifola frondosa (maitake) mushroom hydrolysates: Suppression of vascular remodeling in angiotensin II-induced zebrafish model 灰树花食用菌水解产物中降压肽的鉴定和表征：抑制血管紧张素ii诱导的斑马鱼血管重塑模型

IF 3.8 2区农林科学

Journal of Functional Foods Pub Date : 2025-06-06 DOI: 10.1016/j.jff.2025.106928

Qiaolin Cai , Yuexi Yang , Tiantian Zhang , Yutao Wu , Qing Gong , Binyong Guo , Yin-Yi Ding , Jucai Xu , Zhenyu Gu , Tianyuan Song

{"title":"Identification and characterization of antihypertensive peptides from edible Grifola frondosa (maitake) mushroom hydrolysates: Suppression of vascular remodeling in angiotensin II-induced zebrafish model","authors":"Qiaolin Cai , Yuexi Yang , Tiantian Zhang , Yutao Wu , Qing Gong , Binyong Guo , Yin-Yi Ding , Jucai Xu , Zhenyu Gu , Tianyuan Song","doi":"10.1016/j.jff.2025.106928","DOIUrl":"10.1016/j.jff.2025.106928","url":null,"abstract":"<div><div><em>Grifola frondosa</em> (maitake), a widely consumed edible fungus with documented cardiovascular benefits, is rich in protein and serves as a valuable natural source for bioactive peptide production. Despite its potential, studies on blood pressure-lowering peptides derived from <em>G. frondosa</em> are limited. In this study, we enzymatically hydrolyzed <em>G. frondosa</em> proteins to generate ACE inhibitory peptides, followed by chromatographic separation and purification. Peptidomics-based high-throughput sequencing was used to analyze fractions with potent ACE inhibitory activity, leading to the identification of eight novel peptide sequences (APPLRP, LPPLL, LPPLLL, LPPLPRP, LPPPLLK, LPPRLP, LPPRP, and RPPLP). These peptides were selected based on their amino acid positional characteristics, ADMET properties, and cross-referencing with established databases. Molecular docking analysis revealed that APPLRP and LPPLPRP exhibited the strongest ACE binding affinity, suggesting their superior inhibitory potential. Furthermore, network pharmacology elucidated the mechanistic pathways underlying the antihypertensive effects of these peptides, particularly their role in mitigating angiotensin II-induced vascular remodeling in a zebrafish model.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"130 ","pages":"Article 106928"},"PeriodicalIF":3.8,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144231653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cow milk allergy: Its clinical aspects, mechanisms, and innovative mitigation strategies beyond enzymatic hydrolysis 牛奶过敏：它的临床方面，机制，和创新的缓解策略超越酶水解

IF 3.8 2区农林科学

Journal of Functional Foods Pub Date : 2025-06-06 DOI: 10.1016/j.jff.2025.106933

Min He , Jun Hu , Jiaxin Deng , Xueqiang Chen , Chunhong Liu , Opeyemi Joshua Olatunji , Itthanan Suttikhana , Tolulope Joshua Ashaolu

{"title":"Cow milk allergy: Its clinical aspects, mechanisms, and innovative mitigation strategies beyond enzymatic hydrolysis","authors":"Min He , Jun Hu , Jiaxin Deng , Xueqiang Chen , Chunhong Liu , Opeyemi Joshua Olatunji , Itthanan Suttikhana , Tolulope Joshua Ashaolu","doi":"10.1016/j.jff.2025.106933","DOIUrl":"10.1016/j.jff.2025.106933","url":null,"abstract":"<div><div>Cow milk allergy (CMA) is one of the most common food allergies. Traditional methods for reducing milk allergenicity, such as enzymatic hydrolysis, have limitations, including incomplete allergen degradation and the potential for residual allergenicity. This review aims to provide the current understanding of CMA, including its risk factors, allergen profile, immune mechanisms, and management strategies. It then examines the role of enzymatic hydrolysis in mitigating allergenicity, its applications, and its inherent limitations. Finally, the discussion turns to emerging innovative strategies such as high-pressure processing, pulsed electric fields, advanced glycation end-product modification, and recent advancements in biotechnology, such as CRISPR-Cas9 and microbial engineering which are designed to more effectively degrade cow milk allergens. These approaches aim to reduce allergenicity while preserving the nutritional and functional properties of milk, offering potential advancements in the field, and setting the stage for future directions in both research and clinical practice.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"130 ","pages":"Article 106933"},"PeriodicalIF":3.8,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144222888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Potential role of sublingual-buccal absorption supplementation for binocular function improvement in myopia: A randomized, double-blind, placebo-controlled clinical trial 补充舌下-颊吸收对改善近视患者双眼功能的潜在作用：一项随机、双盲、安慰剂对照的临床试验

IF 3.8 2区农林科学

Journal of Functional Foods Pub Date : 2025-06-06 DOI: 10.1016/j.jff.2025.106931

En-Chieh Lin , Ping-Hsun Wang , Jyh-Cheng Liou , Jia-Lain Wu , Yung-Hsiang Lin , Yan-Zin Chang , Bo-Yi Chen

{"title":"Potential role of sublingual-buccal absorption supplementation for binocular function improvement in myopia: A randomized, double-blind, placebo-controlled clinical trial","authors":"En-Chieh Lin , Ping-Hsun Wang , Jyh-Cheng Liou , Jia-Lain Wu , Yung-Hsiang Lin , Yan-Zin Chang , Bo-Yi Chen","doi":"10.1016/j.jff.2025.106931","DOIUrl":"10.1016/j.jff.2025.106931","url":null,"abstract":"<div><div>Myopic eyes have decreased accommodative responsiveness and weakened binocular vision. Corrective lenses are not completely effective in improving binocular function for myopic individuals, resulting in eye fatigue and blurred vision. This study evaluates a nutraceutical formulation for oral-sublingual-buccal absorption to improve binocular function in individuals with myopia. An 8-week randomized placebo-controlled clinical trial was conducted on 44 myopia patients. The intervention group exhibited significantly improved binocular accommodative facility (BAF) values. In the post-treatment phase, BAF increased by 2.46 ± 3.2 (95 % CI 0.97–4.12) (<em>p</em> < 0.05) compared to the baseline in the intervention group, whereas the placebo group showed a decrease of 0.70 ± 3.20 (95 % CI -2.53–1.00). These findings suggest that oral-sublingual-buccal absorption supplementation may enhance binocular function by improving accommodative facility, refocusing, and visual performance at variance distances. Therefore, it alleviates eye fatigue in myopic individuals, indicating its potential to address limitations in current myopia management.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"130 ","pages":"Article 106931"},"PeriodicalIF":3.8,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144222889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Capparis spinosa significantly improves Th17/Treg imbalance in patients with rheumatoid arthritis: A randomized double blind, placebo-controlled clinical trial in Iran 刺蒺藜显著改善类风湿关节炎患者Th17/Treg失衡：伊朗一项随机双盲、安慰剂对照临床试验

IF 3.8 2区农林科学

Journal of Functional Foods Pub Date : 2025-06-06 DOI: 10.1016/j.jff.2025.106926

Sajad Dehnavi , Zhaleh Shariati-Sarabi , Hassan Rakhshandeh , Mohsen Ghoryani , Jalil Tavakol Afshari , Leila Mobasheri , Mojgan Mohammadi

{"title":"Capparis spinosa significantly improves Th17/Treg imbalance in patients with rheumatoid arthritis: A randomized double blind, placebo-controlled clinical trial in Iran","authors":"Sajad Dehnavi , Zhaleh Shariati-Sarabi , Hassan Rakhshandeh , Mohsen Ghoryani , Jalil Tavakol Afshari , Leila Mobasheri , Mojgan Mohammadi","doi":"10.1016/j.jff.2025.106926","DOIUrl":"10.1016/j.jff.2025.106926","url":null,"abstract":"<div><div><strong><em>Aim:</em></strong> This study investigated the therapeutic effect of <em>C. spinosa</em> on clinical and laboratory indices, and the T lymphocyte populations in refractory female RA patients as a randomized, double-blind placebo-controlled, clinical trial (IRCT20151028024760N5). <strong><em>Materials and Methods:</em></strong> Thirty informed women with refractory RA were randomly divided into three groups including <em>C. spinosa</em>, placebo (, and control. The therapeutic regimen was continued for three consecutive months. Before and after the intervention, patients were evaluated for VAS pain score, DAS28, DAS28-ESR, ESR, CRP, RF, and anti-CCP antibody parameters. Blood samples were also collected to evaluate the percentage of CD4+ T, CD8+ T, Treg, and Th17 cells by flow cytometry. <strong><em>Results and conclusion:</em></strong> <em>C. spinosa</em> treatment significantly reduced VAS pain score (<em>p</em> = 0.0001), DAS28 (<em>p</em> = 0.007), DAS28-ESR (<em>p</em> = 0.001), ESR (<em>p</em> = 0.003), and CRP (<em>p</em> = 0.026) levels. In addition, <em>C. spinosa</em> treatment significantly increased the Treg population (p = 0.02) and Treg/Th17 ratio (<em>p</em> = 0.0015), while decreased Th17 percentage (<em>p</em> = 0.04).</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"130 ","pages":"Article 106926"},"PeriodicalIF":3.8,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144231652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fish skin collagen peptides inhibit melanogenesis by directly regulating the melanocortin 1 receptor 鱼皮胶原蛋白肽通过直接调节黑素皮质素1受体抑制黑色素生成

IF 3.8 2区农林科学

Journal of Functional Foods Pub Date : 2025-06-05 DOI: 10.1016/j.jff.2025.106920

Woo-Jin Sim , Sungmin Cho , Min-Cheol Kang , Kyung-Mo Song , Nam Hyouck Lee , Wook-Chul Kim , Wonchul Lim , Tae-Gyu Lim

{"title":"Fish skin collagen peptides inhibit melanogenesis by directly regulating the melanocortin 1 receptor","authors":"Woo-Jin Sim , Sungmin Cho , Min-Cheol Kang , Kyung-Mo Song , Nam Hyouck Lee , Wook-Chul Kim , Wonchul Lim , Tae-Gyu Lim","doi":"10.1016/j.jff.2025.106920","DOIUrl":"10.1016/j.jff.2025.106920","url":null,"abstract":"<div><div>Excessive exposure to ultraviolet (UV) radiation can induce skin erythema, inflammation, barrier dysfunction, and dryness. Melanin protects against skin dysfunction by absorbing UV light; however, overexposure to UV light causes hyperpigmentation <em>via</em> melanogenesis. Collagen is a major component of the skin barrier and collagen peptides derived from fish skin have been developed as functional ingredients to improve skin health. In this study, we confirmed that collagen peptides inhibit melanogenesis. Collagen peptides significantly reduced melanin content in murine melanoma cells. Furthermore, collagen peptides downregulated the protein expression of tyrosinase, Trp-1, and Trp-2, which are associated with melanin synthesis. Collagen peptides inhibited the cAMP/CREB/MITF and MAPK signaling pathways. Additionally, collagen peptides bind to the melanocortin 1 receptor (MC1R), which upregulates the cAMP/CREB/MITF and MAPK pathways. These findings revealed that collagen peptides exert an anti-melanogenic effect through a direct effect on MC1R. These results suggest that collagen peptides are a promising whitening material for the functional food, skin care, and pharmaceutical industries.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"130 ","pages":"Article 106920"},"PeriodicalIF":3.8,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144212541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anti-inflammatory and immunomodulatory effects in vitro of polysaccharide- and polyphenol-rich extracts of white button and Turkey Tail mushrooms 富多糖和多酚提取物的体外抗炎和免疫调节作用

IF 3.8 2区农林科学

Journal of Functional Foods Pub Date : 2025-06-04 DOI: 10.1016/j.jff.2025.106923

Atefeh Nasri , Julie Anne Lee , H.P. Vasantha Rupasinghe

{"title":"Anti-inflammatory and immunomodulatory effects in vitro of polysaccharide- and polyphenol-rich extracts of white button and Turkey Tail mushrooms","authors":"Atefeh Nasri , Julie Anne Lee , H.P. Vasantha Rupasinghe","doi":"10.1016/j.jff.2025.106923","DOIUrl":"10.1016/j.jff.2025.106923","url":null,"abstract":"<div><div>The health-promoting properties of mushrooms are associated with bioactive natural compounds such as polysaccharides and polyphenols. Anti-inflammatory and immunomodulatory properties of edible white button mushroom (WBM) and medicinal Turkey Tail mushroom (TT) were investigated. The results showed that polysaccharide-rich water extract of WBM and TT exhibit an anti-inflammatory effect in lipopolysaccharide-activated mouse liver cells by attenuating the interleukin (IL)6 and IL1β at mRNA and polysaccharide-rich water extract of WBM by attenuating IL6 and IL1β at protein levels. Also, polysaccharide-rich water and polyphenol-rich ethanolic extracts of WBM stimulated IgA secretion in the human plasma cells (H929 cells) <em>in vitro</em> which was partly mediated by the Signal Transducer and Activator of Transcription 3 (STAT3) pathway. These results suggest that WBM possesses potential anti-inflammatory and immune-enhancing properties and could be further assessed for use as a dietary supplement against inflammation and boosting immunity simultaneously.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"130 ","pages":"Article 106923"},"PeriodicalIF":3.8,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144203519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cultivated Cordyceps militaris exerts anti-allergic effects in a cockroach-induced allergic dermatitis mouse model by suppressing inflammation and enhancing epidermal homeostasis 培养的蛹虫草通过抑制炎症和增强表皮稳态，在蟑螂诱导的过敏性皮炎小鼠模型中发挥抗过敏作用

IF 3.8 2区农林科学

Journal of Functional Foods Pub Date : 2025-06-04 DOI: 10.1016/j.jff.2025.106925

Mey-Fann Lee , Jane-Yii Wu , Chi-Sheng Wu , Ming-Hao Lee , Yu-Wen Chu

引用次数: 0