Journal of Functional Foods最新文献_第6页

Preparation and characterization of Sipunculus nudus peptide-calcium chelate: Structural insights and osteogenic bioactivity assessment Sipunculus nudus 肽钙螯合物的制备与表征：结构见解和成骨生物活性评估

IF 3.8 2区农林科学

Journal of Functional Foods Pub Date : 2024-11-01 DOI: 10.1016/j.jff.2024.106497

Qianqian Ouyang , Yuwei Jiang , Lifen Liu , Chengfeng Cai , Nandika Bandara , Puwang Li , Kefeng Wu , Hui Hong , Liang Chen

{"title":"Preparation and characterization of Sipunculus nudus peptide-calcium chelate: Structural insights and osteogenic bioactivity assessment","authors":"Qianqian Ouyang , Yuwei Jiang , Lifen Liu , Chengfeng Cai , Nandika Bandara , Puwang Li , Kefeng Wu , Hui Hong , Liang Chen","doi":"10.1016/j.jff.2024.106497","DOIUrl":"10.1016/j.jff.2024.106497","url":null,"abstract":"<div><div>In order to prepare calcium supplements for efficient absorption and utilization in the human body, this study focused on synthesizing SNP-Ca by chelating <em>Squarrosus nudus</em> peptide (SNP) with calcium. We characterized its structure, stability, and calcium uptake properties in Caco-2 cells and its impact on osteogenic activity in vitro. Optimal preparation conditions were determined: a peptide-calcium mass ratio of 5:1, a 30-min reaction time, a temperature of 60 °C, and a pH of 7.0. Under these conditions, a calcium chelating rate of 68.32 % was achieved. Calcium binds to the peptide primarily via carboxyl oxygen and amino nitrogen atoms, and the morphology of SNP-Ca was similar to porous nanoflowers. Our cellular experiments revealed that SNP-Ca significantly increases calcium uptake in Caco-2 cells, stimulating proliferation, differentiation, and mineralization in MC3T3-E1 cells. Additionally, zebrafish larvae models showed enhanced bone formation following SNP-Ca administration. SNP-Ca has the potential of a novel calcium supplement.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"122 ","pages":"Article 106497"},"PeriodicalIF":3.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142656407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The impact of AP collagen peptides (APCPs) on hair shaft elasticity and gloss: A comprehensive analysis AP胶原蛋白肽（APCPs）对发轴弹性和光泽度的影响：综合分析

IF 3.8 2区农林科学

Journal of Functional Foods Pub Date : 2024-11-01 DOI: 10.1016/j.jff.2024.106534

Ahreum Kim , Yujin Kim , Jung Min Lee , Jin-Oh Chung , Jong Hwa Roh , Jung Ok Lee , Beom Joon Kim

{"title":"The impact of AP collagen peptides (APCPs) on hair shaft elasticity and gloss: A comprehensive analysis","authors":"Ahreum Kim , Yujin Kim , Jung Min Lee , Jin-Oh Chung , Jong Hwa Roh , Jung Ok Lee , Beom Joon Kim","doi":"10.1016/j.jff.2024.106534","DOIUrl":"10.1016/j.jff.2024.106534","url":null,"abstract":"<div><div>AP collagen peptides (APCPs) are enzymatically decomposed collagen peptides that have been shown to promote hair growth and improve hair cuticle structure and thickness in mice. However, their impact on the elasticity and gloss of human hair has not been thoroughly investigated. Therefore, this study sought to identify the factors affecting hair elasticity and gloss in APCPs-treated human hair follicles (hHFs). Using Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) analysis, changes in amino acid content related to hair elasticity and lipid components associated with hair gloss were measured. As a result, APCP treatment led to increases in proline and cysteine amino acid, as well as in lipid components such as 18-methyleicosanoic acid (18-MEA), lauric acid, oleic acid, 11,13-eicosenoic acid, behenic acid, methyleicosanoic acid and squalene. Fourier-transform infrared spectroscopy (FT-IR) analysis of hair cross-sections indicated an increase in the intensity of bonds such as S=O, C=O, cystine, C–N and C–H in APCPs-treated hHFs. Additionally, APCPs elevated the expression of Keratin 17, integral to the inner root sheaths (IRS) and outer root sheaths (ORS), as well as Keratins 31, 85, and 86, components of the hair cortex and medulla. APCPs treatment also resulted in increased bonded water and moisture content in hHFs, along with a reduction in cuticle surface roughness. These findings suggest that APCPs may have the potential to enhance hair elasticity and gloss.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"122 ","pages":"Article 106534"},"PeriodicalIF":3.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142656474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of walnut shell extract on lipid metabolism and serum metabolomics in rats with high-fat diet-induced obesity 核桃壳提取物对高脂饮食诱发肥胖大鼠脂质代谢和血清代谢组学的影响

IF 3.8 2区农林科学

Journal of Functional Foods Pub Date : 2024-11-01 DOI: 10.1016/j.jff.2024.106558

Xu Zhang , Yan Luo , Li Qin , Yage Ma , Dan Chen , Shenglan Zhao

引用次数: 0

Galangin alleviates alcoholic liver disease by regulating the gut-liver axis 高良姜素通过调节肠肝轴缓解酒精性肝病

IF 3.8 2区农林科学

Journal of Functional Foods Pub Date : 2024-11-01 DOI: 10.1016/j.jff.2024.106506

Dongzhu Duan, Zhenzhen Du, Ling Zhao

引用次数: 0

The therapeutic perspective of cinnamon (Cinnamomum verum) consumption against metabolic syndrome 食用肉桂（Cinnamomum verum）对代谢综合征的治疗前景

IF 3.8 2区农林科学

Journal of Functional Foods Pub Date : 2024-11-01 DOI: 10.1016/j.jff.2024.106545

Tehmina Bibi , Ammar B. Altemimi , Roshina Rabail , Seemal Munir , Muhammad Umar Shahbaz , Maryam Khalid Rizvi , Muhammad Faisal Manzoor , Gholamreza Abdi , Ahsan Ul Haq , Rana Muhammad Aadil

{"title":"The therapeutic perspective of cinnamon (Cinnamomum verum) consumption against metabolic syndrome","authors":"Tehmina Bibi , Ammar B. Altemimi , Roshina Rabail , Seemal Munir , Muhammad Umar Shahbaz , Maryam Khalid Rizvi , Muhammad Faisal Manzoor , Gholamreza Abdi , Ahsan Ul Haq , Rana Muhammad Aadil","doi":"10.1016/j.jff.2024.106545","DOIUrl":"10.1016/j.jff.2024.106545","url":null,"abstract":"<div><div>Metabolic syndrome (MetS)is one of the most significant worldwide public health issues. Hypertension, visceral obesity, hyperglycemia, dyslipidemia, and insulin resistance are some of the contributing variables. The latest MetS preventative measures have focused on lifestyle factors and combination therapy, including exercise and herbal treatment. Cinnamon <em>(Cinnamomum verum)</em> is rich in phytochemicals, including phenolic and volatile compounds, responsible for its antitumor, anticancer, antidiabetic, and anti-hypertriglyceridemia potentials. Numerous clinical studies have demonstrated the value of cinnamon’s anti-inflammatory properties in treating diabetes. Cinnamon is crucial in maintaining normal levels of lipids in the blood. In the past ten years, several clinical studies have examined the effectiveness of cinnamon administration in managing inflammation-related diseases,metabolic abnormalities, and polycystic ovarian syndrome. Comprehensive information about the chemical composition, nutritional compounds, phytoconstituents, and protective role of cinnamon and cinnamaldehyde against metabolic syndrome has been presented in this review. An effort has also been made to explain the mechanisms of blood glucose management, visceral obesity management, and cinnamon safety and toxicity aspects.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"122 ","pages":"Article 106545"},"PeriodicalIF":3.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142552061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy of walnut supplementation in managing overweight and obesity: A meta-analysis of randomized clinical trials 核桃补充剂在控制超重和肥胖方面的功效：随机临床试验荟萃分析

IF 3.8 2区农林科学

Journal of Functional Foods Pub Date : 2024-11-01 DOI: 10.1016/j.jff.2024.106515

Wen Liu , Enqiang Li , Mingdong Hu

引用次数: 0

Anti-proliferation effect of chitooligosaccharide on colitis-associated cancer in mice: Possible involvement of miRNA-155/TLR4/Reg3g pathway 壳寡糖对小鼠结肠炎相关癌症的抗增殖作用：miRNA-155/TLR4/Reg3g通路的可能参与

IF 3.8 2区农林科学

Journal of Functional Foods Pub Date : 2024-11-01 DOI: 10.1016/j.jff.2024.106560

Xiwei Liu , Yichao Ma , Jie Guo, Jun Wang

{"title":"Anti-proliferation effect of chitooligosaccharide on colitis-associated cancer in mice: Possible involvement of miRNA-155/TLR4/Reg3g pathway","authors":"Xiwei Liu , Yichao Ma , Jie Guo, Jun Wang","doi":"10.1016/j.jff.2024.106560","DOIUrl":"10.1016/j.jff.2024.106560","url":null,"abstract":"<div><div>Chronic colonic inflammation might result in increased cell proliferation that poses risk of colitis-associated cancer(CAC), an aggressive subtype of colorectal cancer. This study aimed to investigate dietary intervention effect and mechanism of chitooligosaccharide(COS) on azoxymethane(AOM)/dextran sulfate sodium(DSS)-induced CAC development in mice. COS at dose of 500 mg/kg markedly suppressed colonic levels of tumor necrosis factor(TNF)-α, interleukin(IL)-1β, and IL-6 in CAC mice. Compared to CAC model controls, the number of colonic epithelial cells expressing Ki-67 and the colonic expression levels of cyclin D1 were decreased in COS-treated CAC mice. COS administration significantly down-regulated expression of micro(mi)RNA-155, toll-like receptor(TLR)4, nuclear factor-kappaB(NF-κB), phosphorylated signal transducer and activator of transcription protein 3(pSTAT3), and regenerating islet derived 3 gamma(Reg3g), whereas up-regulated the suppressors of cytokine signaling 1 (SOCS1) expression in CAC colons. Overall, COS exerted protective activity against AOM/DSS-induced colitis-associated carcinogenesis, mechanism of which was associated with its anti-proliferation effect possible <em>via</em> regulating miRNA-155/TLR4/Reg3g pathway.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"122 ","pages":"Article 106560"},"PeriodicalIF":3.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142656459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Salvianolic acid B improves DEN/CCl4/C2H5OH-induced renal fibrosis by regulating YAP/TAZ and pSmad3C/pSmad3L 丹酚酸B通过调节YAP/TAZ和pSmad3C/pSmad3L改善DEN/CCl4/C2H5OH诱导的肾纤维化

IF 3.8 2区农林科学

Journal of Functional Foods Pub Date : 2024-11-01 DOI: 10.1016/j.jff.2024.106553

Lili Li , Zhenghao Shi , Yuxuan Li , Jiacheng Xu , Shuchen Han , Jinyan Chen , Hanyang Xu , Jiemei Jiang , Yan Yang , Yongfang Gong

{"title":"Salvianolic acid B improves DEN/CCl4/C2H5OH-induced renal fibrosis by regulating YAP/TAZ and pSmad3C/pSmad3L","authors":"Lili Li , Zhenghao Shi , Yuxuan Li , Jiacheng Xu , Shuchen Han , Jinyan Chen , Hanyang Xu , Jiemei Jiang , Yan Yang , Yongfang Gong","doi":"10.1016/j.jff.2024.106553","DOIUrl":"10.1016/j.jff.2024.106553","url":null,"abstract":"<div><div>Salvianolic acid B (Sal B) is a natural compound extracted from the root of <em>Salvia miltiorrhiza</em>, which has multiple biological activities. Targeting Hippo pathway transcriptional coactivators YAP/TAZ combined with Smad3 is an effective strategy against renal fibrosis. However, whether Sal B improves DEN/CCl<sub>4</sub>/C<sub>2</sub>H<sub>5</sub>OH-induced renal fibrosis and regulates YAP/TAZ and Smad3 phospho-isoform, pSmad3C/pSmad3L is unknown. Presently, we used DEN/CCl<sub>4</sub>/C<sub>2</sub>H<sub>5</sub>OH to induce renal fibrosis in mice and TGF-β1 or MST1/2 inhibitor XMU-MP-1 to induce HK-2 cells to investigate the activity and molecular mechanisms of Sal B. The results demonstrated that Sal B ameliorated DEN/CCl<sub>4</sub>/C<sub>2</sub>H<sub>5</sub>OH-induced renal fibrosis, including reducing renal tissue injury, improving renal function, and decreasing collagen synthesis. Furthermore, Sal B downregulated YAP/TAZ and promoted their phosphorylation <em>in vivo</em> and <em>in vitro.</em> Moreover, Sal B upregulated pSmad3C but downregulated pSmad3L <em>in vivo</em> and <em>in vitro</em>. Collectively, this study revealed that Sal B may improve DEN/CCl<sub>4</sub>/C<sub>2</sub>H<sub>5</sub>OH-induced renal fibrosis by regulating YAP/TAZ and pSmad3C/pSmad3L.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"122 ","pages":"Article 106553"},"PeriodicalIF":3.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142656473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Purification, structural analysis, and hypoglycemic activity of Auricularia auricula-judae polysaccharides extracted with natural deep eutectic solvents 用天然深共晶溶剂提取的 Auricularia auricula-judae 多糖的纯化、结构分析和降血糖活性

IF 3.8 2区农林科学

Journal of Functional Foods Pub Date : 2024-11-01 DOI: 10.1016/j.jff.2024.106524

Yemei Dai , Yujing He , Yuan Ma, Xuan Yang, Yongli Huang, Hongmei Min, Xiaocui Liu

{"title":"Purification, structural analysis, and hypoglycemic activity of Auricularia auricula-judae polysaccharides extracted with natural deep eutectic solvents","authors":"Yemei Dai , Yujing He , Yuan Ma, Xuan Yang, Yongli Huang, Hongmei Min, Xiaocui Liu","doi":"10.1016/j.jff.2024.106524","DOIUrl":"10.1016/j.jff.2024.106524","url":null,"abstract":"<div><div>The <em>in vitro</em> research found that <em>Auricularia auricula-judae (A. auricula</em>) crude polysaccharides showed hypoglycemic and antioxidant properties, whereas purified polysaccharides were more effective. <em>A. auricula</em> polysaccharide was identified as a typical heteropolysaccharide, with a pyran-type sugar ring coupled via α- and β-type glycosidic linkage. The monosaccharide composition includes Man, Xyl, Ara, Glc, Rha, and galactose (Gal), at a molar ratio of 61.36:37.92:36.27:25.79:24.30:20.38, while also containing a small amount of galacturonic and glucuronic acid. <em>A. auricula</em> polysaccharide showed smooth, flaky structures, with a small portion exhibiting a filamentous and spherical morphology. <em>A. auricula</em> polysaccharides activate glycogen synthetase kinase 3β (GSK3β) phosphorylation, leading to increased hepatic glycogen production, and they reduce glucose synthesis and lower blood sugar levels by decreasing phosphoenolpyruvate carboxykinase (PEPCK) and glucose-6-phosphatase (G6Pase) enzyme activity, and enhancing FOXO1 phosphorylation. The findings suggested that <em>A. auricula</em> polysaccharides could be used as natural hypoglycemic agents.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"122 ","pages":"Article 106524"},"PeriodicalIF":3.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142552057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Release of bioactive peptides from whey proteins across digestion in adult humans and a static in vitro digestion model 成人和静态体外消化模型在消化过程中释放乳清蛋白中的生物活性肽

IF 3.8 2区农林科学

Journal of Functional Foods Pub Date : 2024-11-01 DOI: 10.1016/j.jff.2024.106540

Suwimon Sutantawong , Bum Jin Kim , Russell F. Kuhfeld , Yunyao Qu , David C. Dallas

引用次数: 0