Environmental PollutionPub Date : 2026-10-15Epub Date: 2026-07-28DOI: 10.1016/j.envpol.2026.128835
Ziyi Zhou, Bin Sun, Yudiyang Ma, Ning Chen, Haibo Li, Wenpu Shao, Rui Tang, Lei Zheng, Meiqi Xing, Xinru Zhao, Yibing Zhu, Yaohua Tian
{"title":"Maternal exposure to particulate matter during pregnancy and offspring liver function.","authors":"Ziyi Zhou, Bin Sun, Yudiyang Ma, Ning Chen, Haibo Li, Wenpu Shao, Rui Tang, Lei Zheng, Meiqi Xing, Xinru Zhao, Yibing Zhu, Yaohua Tian","doi":"10.1016/j.envpol.2026.128835","DOIUrl":"10.1016/j.envpol.2026.128835","url":null,"abstract":"<p><p>Air pollution is associated with hepatic dysfunction, but the evidence in the early childhood remains limited. This study aimed to explore the associations between maternal exposure to particulate matter and offspring liver function, as indicated by serum levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in children aged 1-2 years. Based on the Fujian Birth Cohort Study (FJBCS), a total of 1046 mother-offspring pairs were analyzed in this study. Maternal mean exposures to PM<sub>1</sub>, PM<sub>2.5</sub> and PM<sub>10</sub> were calculated for the entire gestational period and each of the three trimesters. Linear regression models were used and restricted cubic spline (RCS) models were further applied to explore the exposure-response relationships. Distributed lag models (DLMs) were conducted to examine the weekly associations throughout pregnancy. Results show that positive associations were found between maternal exposure and offspring enzyme levels in the entire pregnancy as well as the second trimester alone. After adjustment, an interquartile range (IQR) increment in PM<sub>1</sub>, PM<sub>2.5</sub> and PM<sub>10</sub> in the second trimester was associated with increases in ALT by 1.42 (0.82-2.03) U/L, 1.41 (0.77-2.05) U/L, 0.91 (0.35-1.46) U/L, and in AST by 1.64 (1.00-2.29) U/L, 1.56 (0.88-2.23) U/L and 0.80 (0.21-1.39) U/L, respectively. DLM analyses further indicated that the associations were the most pronounced during the second trimester. Our findings suggest that maternal exposure to particulate matter is positively associated with increased levels of ALT and AST in offspring, with the second trimester representing a potentially sensitive period.</p>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":" ","pages":"128835"},"PeriodicalIF":7.2,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148597156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Chronic exposure to environmentally relevant diazepam alters behaviour, gut microbiome, and offspring phenotype in zebrafish (Danio rerio).","authors":"Ting Xu, Yilin Huang, Guiling Yang, Wenqin Tu, Ting Luo, Dou Wang, Yuanxiang Jin","doi":"10.1016/j.envpol.2026.128837","DOIUrl":"10.1016/j.envpol.2026.128837","url":null,"abstract":"<p><p>The widespread consumption and incomplete wastewater removal of the psychoactive drug diazepam (DZP) have led to its ubiquitous presence in aquatic environments, posing profound ecological risks. While the direct toxicity of DZP is well-documented, its chronic and mechanistic impacts, particularly those concerning the gut-brain axis and intergenerational effects on offspring, remain largely unexplored. To investigate the multigenerational toxicity of DZP, adult female zebrafish were chronically exposed to environmentally relevant concentrations (1 and 10 μg/L) for 28 days, and their offspring were subsequently collected. Our findings revealed that DZP exposure induced severe gut damage and disrupted the gut microbiota and metabolite profiles in female zebrafish. This microecological dysbiosis was linked to impaired oocyte development and reduced brain γ-aminobutyric acid (GABA) levels, culminating in reproductive dysfunction and abnormal neurobehavior. Crucially, these toxicological effects were maternally transferred to the offspring, which exhibited corresponding developmental abnormalities and neurobehavioral deficits. Overall, this study demonstrates that environmentally relevant concentrations of DZP exert covert but profound intergenerational toxicity, potentially mediated by disruptions in the gut-brain axis, making it highly necessary to establish stricter regulatory guidelines regarding the discharge of psychoactive drugs into water environments.</p>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":" ","pages":"128837"},"PeriodicalIF":7.2,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148597125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammad Gholizadeh, Alessandra Cera, Andi Kurniawan, Nurul Huda
{"title":"Spatial Heterogeneity of Microplastic Contamination in Coastal Surface Waters: A Case Study of 21 Stations in the Southern Caspian Sea, Iran.","authors":"Mohammad Gholizadeh, Alessandra Cera, Andi Kurniawan, Nurul Huda","doi":"10.1016/j.envpol.2026.129322","DOIUrl":"https://doi.org/10.1016/j.envpol.2026.129322","url":null,"abstract":"<p><p>Microplastic (MP) pollution poses significant threats to coastal ecosystems, yet data on its distribution in the southern Caspian Sea remain limited. This study provides one of the first comprehensive regional assessments of MP contamination in coastal surface waters along the Iranian Caspian coastline. Surface-water samples were collected from Gilan, Mazandaran, and Golestan provinces at three distances from the shoreline. MPs were extracted using density separation and oxidative digestion, characterized by stereomicroscopy and polymer-confirmed by FTIR-ATR. MPs were detected at all 21 sampling stations, with concentrations ranging from 0.05 to 1.30 MPs/L and a mean abundance of 0.24 0.05 MPs/L. MP abundance decreased significantly with increasing distance from shore (p < 0.001), indicating dominant land-based pollution sources. Mazandaran province exhibited the highest contamination levels, associated with intensive tourism and urbanization. Land-use analysis revealed that areas experiencing combined anthropogenic pressures had significantly greater MP abundance than single-activity areas. Fibers dominated particle morphology (73.4%), while polyethylene and polypropylene were the most abundant polymers, reflecting contributions from consumer plastics, packaging materials, and fishing-related activities. Multivariate analysis identified distinct pollution signatures associated with tourism, urbanization, and fisheries. These findings establish a critical baseline for future monitoring. Improved coastal waste management, tourism controls, and sustainable fishing practices are essential to mitigate MP pollution in this ecologically vulnerable inland sea.</p>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":" ","pages":"129322"},"PeriodicalIF":7.2,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149190477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Environmental PollutionPub Date : 2026-10-15Epub Date: 2026-06-15DOI: 10.1016/j.envpol.2026.128578
Qian Liao, Huishen Huang, Rongrui Huo, Jun Liang, Xiaoqiang Qiu
{"title":"Prenatal exposure to per- and polyfluoroalkyl substances and postpartum new-onset hypertension: Mediating role of systemic inflammation indicators.","authors":"Qian Liao, Huishen Huang, Rongrui Huo, Jun Liang, Xiaoqiang Qiu","doi":"10.1016/j.envpol.2026.128578","DOIUrl":"10.1016/j.envpol.2026.128578","url":null,"abstract":"<p><p>Postpartum blood pressure (BP) is strongly associated with increased cardiovascular risk for women. However, evidence concerning the relationship between prenatal per- and polyfluoroalkyl substance (PFAS) exposure and postpartum new-onset hypertension (PNH) is scarce. The aim of this study was to examine the associations between prenatal PFAS exposure and PNH risk and to assess the potential mediating role of systemic inflammation indicators in these associations. A total of 826 pregnant women from the Guangxi Zhuang Birth Cohort in China with complete PFAS measurement and routine blood test data during early pregnancy, along with BP monitoring during the 7-day and 42-day postpartum follow-up visits, were included. Associations with PNH risk were assessed using restricted cubic splines and logistic regression for individual PFAS exposure and a Bayesian kernel machine and weighted quantile sum regression for PFAS mixture exposure. Furthermore, a simple mediation analysis was performed to estimate the proportion of effects mediated by systemic inflammation indicators (NLR, MLR, PLR, SII, SIRI, and PIV). Perfluorobutane sulfonate (PFBS) was positively associated with PNH risk according to single-exposure analyses. PFAS mixtures also showed positive associations, with PFBS as the main contributor. The NLR (5.5%), SII (9.8%), SIRI (7.6%), and PIV (11.2%) partially mediated the positive association of individual PFBS exposure with PNH risk, and SII (8.5%), SIRI (6.3%), and PIV (9.6%) partially mediated the positive association of the PFAS mixture with PNH risk. In summary, prenatal exposure to PFAS, especially PFBS, is associated with an increased risk of PNH, partially through systemic inflammation activation. These findings highlight short-chain PFAS as potential novel risk factors for long-term cardiovascular health in women. Future research should specifically investigate inflammation-related signaling pathways linking prenatal PFAS exposure to PNH, as these findings may provide a basis for targeted interventions and mechanistic insights.</p>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":" ","pages":"128578"},"PeriodicalIF":7.2,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148256654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Environmental PollutionPub Date : 2026-10-15Epub Date: 2026-07-19DOI: 10.1016/j.envpol.2026.128801
Patricia González-Palacios, Moustapha Sy, Thomas Tietz, Claudia Lorenz, Ralph Pirow, Vega Almazán-Fernández de Bobadilla, Ana Rivas, Alberto Zafra-Gómez
{"title":"Assessment of the exposure of Spanish children and adolescents to bisphenols and parabens using dietary and human biomonitoring data.","authors":"Patricia González-Palacios, Moustapha Sy, Thomas Tietz, Claudia Lorenz, Ralph Pirow, Vega Almazán-Fernández de Bobadilla, Ana Rivas, Alberto Zafra-Gómez","doi":"10.1016/j.envpol.2026.128801","DOIUrl":"10.1016/j.envpol.2026.128801","url":null,"abstract":"<p><p>Bisphenols A and S (BPA, BPS) and methylparaben (MetPB) are considered endocrine disrupting chemicals (EDCs). The development of approaches for more realistic estimation of exposure to these EDCs is crucial for understanding the extent of the actual burden in the population. Dietary exposure to BPA, BPS, and MetPB in Spanish children (3-12 years old) was estimated using 3 different approaches. The 24-h dietary recall (R24h) and food frequency questionnaire (FFQ) were used, together with reverse dosimetry applied to human biomonitoring (HBM) data to calculate daily intake (DI). Based on R24h and FFQ, average daily intakes for a total of 389 children were estimated to be 211/344, 148/469 and 3443/6185 ng·kg<sup>-1</sup> per day for BPA, BPS and MetPB, respectively. Substantially lower values (56, 17 and 685 ng·kg<sup>-1</sup> per day) were estimated from HBM data for BPA, BPS and MetPB, respectively. Based on R24h and DI-derived exposure estimates for BPA, the proportion of the population exceeding the EFSA TDI was 98.7 % and 100 %, respectively. In contrast, 38.6 % (R24h) and 3.9 % (DI) of the study population were observed to exceed the BfR TDI. The present study provides novel data on exposure to bisphenols and parabens using three complementary approaches: FFQ, R24h and HBM. Overall, R24h and FFQ yielded comparable exposure values; however, differences between methods should be interpreted in consideration of their distinct methodological assumptions and temporal representativeness. In contrast, HBM may not fully capture daily dietary intake due to its reliance on a single spot urine sample instead of a 24h sample. Further studies on exposure should be conducted in order to gather more data for comparison.</p>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":" ","pages":"128801"},"PeriodicalIF":7.2,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148519635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Environmental PollutionPub Date : 2026-10-15Epub Date: 2026-07-28DOI: 10.1016/j.envpol.2026.128842
Linhai Ye, Zhengyu Wang, Feng Chen, Xu Xing, Cheng Zeng, Tao Zhou, Youcai Zhao
{"title":"Release and redistribution of rare earth elements from coal ash in simulated landfill systems.","authors":"Linhai Ye, Zhengyu Wang, Feng Chen, Xu Xing, Cheng Zeng, Tao Zhou, Youcai Zhao","doi":"10.1016/j.envpol.2026.128842","DOIUrl":"10.1016/j.envpol.2026.128842","url":null,"abstract":"<p><p>Municipal landfills have historically co-disposed coal ash (CA) and other solid wastes containing rare earth elements and yttrium (REY). However, REY mobility and their dynamics between residues and leachate during waste stabilization remain poorly understood. This study constructed bench-scale landfill reactors amended with CA and organic waste (OW) to resolve REY leaching and quantify their interactions with dissolved organic matter (DOM) in leachate. During OW biodegradation, accumulation of volatile fatty acids coincided with a decrease in pH and an increase in REY concentration, particularly from exchangeable, acid-soluble, and reducible solid fractions. With pH recovery to neutral-alkaline conditions, DOM became the dominant control on dissolved REY through complexation, with binding contributions ranked as fulvic-like > tyrosine-like > tryptophan-like components. Complexation was driven primarily by carboxylic, polysaccharide C-O, amide carbonyl, and phenolic hydroxyl groups. As OW decomposed, newly formed organo-mineral interfaces developed on CA surfaces. Sorption on organo-mineral surfaces increased REY retention during leachate recirculation. These results explain the partitioning of REY among landfill stabilization products (leachate and humidified fraction) and provide a mechanistic foundation for assessing the potential recovery of REY in the context of landfill mining.</p>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":" ","pages":"128842"},"PeriodicalIF":7.2,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148597112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Contaminant class reconfigures the effect of predators on prey: A meta-analytic synthesis of aquatic invertebrate responses across pollution scenarios.","authors":"Hengnan Chen, Keyi Wang, Qiming Jiang, Danjuan Zeng, Junbo Yang, Xiaohui Wang, Liangliang Huang, Gaozhong Pu","doi":"10.1016/j.envpol.2026.129328","DOIUrl":"10.1016/j.envpol.2026.129328","url":null,"abstract":"<p><p>Predation risk and chemical contamination are pervasive stressors in aquatic ecosystems; however, their interactive effects remain insufficiently understood. This meta-analysis synthesizes evidence from 41 independent studies across four scenarios: unpolluted, organic pollution, inorganic pollution, and mixed pollution. Under unpolluted conditions, we show that predation pressure consistently suppresses physiological performance in aquatic invertebrates while eliciting adaptive behavioral responses. Notably, the type of pollutant fundamentally reshapes this response pattern. Organic pollutants attenuate physiological responses and impair behavioral decision-making through energy trade-offs and neurotoxic effects. In contrast, inorganic pollutants enhance morphological defenses while concurrently weakening other physiological and behavioral responses. Mixed pollutants amplify biochemical costs and reduce behavioral effectiveness of predation avoidance, though the underlying mechanisms remain poorly understood. The analysis of the response differences among various invertebrate groups revealed that their responses to predation pressure reflected their unique life history strategies. Taken together, our findings demonstrate that pollutants do not merely add to predation stress; rather, they fundamentally reconfigure how organisms allocate resources among survival, growth, and reproduction. These insights carry important implications for predicting ecosystem responses under intensifying anthropogenic stress.</p>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":" ","pages":"129328"},"PeriodicalIF":7.2,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149190395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Environmental PollutionPub Date : 2026-10-15Epub Date: 2026-07-29DOI: 10.1016/j.envpol.2026.128857
Huichen Lu, Ling Yao, Siyu Wang, Yuanyuan Hu, Zhenfeng Wang, Randy A Dahlgren, Xianlei Cai
{"title":"Properties of free-living and particle-attached potentially pathogenic bacterial communities in a hypereutrophic urban river network.","authors":"Huichen Lu, Ling Yao, Siyu Wang, Yuanyuan Hu, Zhenfeng Wang, Randy A Dahlgren, Xianlei Cai","doi":"10.1016/j.envpol.2026.128857","DOIUrl":"10.1016/j.envpol.2026.128857","url":null,"abstract":"<p><p>Pathogenic bacteria are ubiquitously detected in various natural and artificial water systems, posing potential threats to public health and safety. To elucidate the structure of potentially pathogenic bacterial communities and their spatio-temporal patterns, a two-year study examined four contrasting land-use/land-cover types (urban, industrial, agricultural, natural forest) in a hypereutrophic urban river network of eastern China. Three predominant potentially pathogenic species appeared in both the particle-attached (PA) and free-living (FL) bacterial communities: Flavobacterium succinicans, Arcobacter cryaerophilus, and Aeromonas hydrophila. The richness, relative abundances, community complexity and stability of potentially pathogenic bacteria were generally higher in the PA fraction than those in the FL fraction. Moreover, higher concentrations of suspended particles appeared to increase the similarity in potentially pathogenic bacterial community composition between PA and FL assemblages. Redundancy analysis demonstrated that water temperature was the most influential water quality variable shaping the seasonal changes of potentially pathogenic bacterial community. The relative abundance of potentially pathogenic bacterial species in the urban river environment showed marked changes related to seasons, with its relative abundance appreciably higher in the winter dry season (January). Although the assembly mechanisms of potentially pathogenic bacterial communities were more stochastic than deterministic, those in the river surrounded by agricultural land were more deterministic compared to with other land-use/land-cover types. Potentially pathogenic bacterial communities with a high proportion of positive correlations might have weak stability. These findings increase our understanding of potentially pathogenic bacterial community characteristics in hypereutrophic urban river ecosystems and provide valuable insights for environmental and public health management.</p>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":" ","pages":"128857"},"PeriodicalIF":7.2,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148617698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"DeepLitterAI: Automated detection and quantification of deep-sea benthic plastic and macrolitter with field validation in waters around Japan.","authors":"Ryota Nakajima, Takaki Nishio, Hideaki Saito, Shintaro Kawahara, Daisuke Matsuoka","doi":"10.1016/j.envpol.2026.129004","DOIUrl":"10.1016/j.envpol.2026.129004","url":null,"abstract":"<p><p>Deep-sea imagery is a non-destructive tool for monitoring seafloor litter, but manual inspection limits its scalability. DeepLitterAI, a YOLOv11x-based detector combined with BoT-SORT tracking, was developed to automatically detect and quantify deep-sea benthic macrolitter. The model was trained with J-Litter, a dataset of 12,029 annotated images extracted from footage acquired by the Japan Agency for Marine-Earth Science and Technology (JAMSTEC) between 1983 and 2025. J-Litter includes small litter objects and non-litter images. DeepLitterAI was compared with a model trained only on large, clearly visible litter to evaluate training-data bias. On realistic test images containing small objects, DeepLitterAI achieved average precision (AP), which summarizes precision-recall performance, of 0.79-0.81 and F<sub>1</sub> scores, defined as the harmonic mean of precision and recall, of 0.71-0.76 for plastic films, plastic bottles, and beverage cans (mean AP@0.5 = 0.80 and mean F<sub>1</sub> = 0.73), with AP values averaging 1.6-fold higher than those of the large-object model. In six independent survey videos acquired at depths of 860-5641 m, using manual inspection as the reference, DeepLitterAI achieved F<sub>1</sub> scores of 0.65-0.89, with a mean of 0.77 across categories. AI-derived total litter density averaged 1.1 times the manual estimate. AI analysis was 1.5-3.1 times faster than manual inspection, with a mean speed-up of 2.1-fold. Performance was robust to viewing angle, whereas false-negative rate increased to 25% under the highest synthetic turbidity condition. DeepLitterAI provides a scalable, non-destructive framework for standardized monitoring and mapping of deep-sea macrolitter.</p>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":" ","pages":"129004"},"PeriodicalIF":7.2,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148786437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Environmental PollutionPub Date : 2026-10-15Epub Date: 2026-07-24DOI: 10.1016/j.envpol.2026.128826
Valeria Vargas, Guadalupe E Ángeles-López, Jorge Cime-Castillo, Mariana Segovia-Mendoza
{"title":"Endocrine disrupting chemicals and their effects on mosquito vectors of infectious diseases: A narrative review.","authors":"Valeria Vargas, Guadalupe E Ángeles-López, Jorge Cime-Castillo, Mariana Segovia-Mendoza","doi":"10.1016/j.envpol.2026.128826","DOIUrl":"10.1016/j.envpol.2026.128826","url":null,"abstract":"<p><p>Endocrine-disrupting chemicals (EDCs), including bisphenols, phthalates, polyfluoroalkyl substances (PFAS), household antimicrobials such as triclosan, and insect growth regulators (IGRs) that mimic juvenile hormones, are increasingly present in mosquito larval habitats. In Aedes, Culex, and Anopheles, sublethal exposures may alter endocrine pathways (juvenile hormone, ecdysteroids, insulin/IGF-TOR), life history traits (developmental time, fecundity, longevity), midgut physiology, and immune function, with potential consequences for vector competence. Recent evidence has shown that bisphenol A (BPA) modulates the development and antiviral immunity of Aedes aegypti mosquitoes. In Culex quinquefasciatus, BPA accelerates development through ecdysteroid signaling, PFAS reduce survival and alter larval behavior, and IGRs, such as pyriproxyfen and methoprene, although used as vector control tools, exert collateral endocrine effects on reproduction and adult longevity. In this review, we synthesize the current knowledge, discuss the mechanistic insights, highlight the ecological relevance, and identify the major research gaps.</p>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":" ","pages":"128826"},"PeriodicalIF":7.2,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148576488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}