Environmental Pollution最新文献

{"title":"Genome-informed monitoring and characterization of Escherichia coli, including shiga toxin-producing strains, in a river with diverse land uses.","authors":"Shunsuke Iriguchi, Ryutaro Matsuyama, Miki Okuno, Soichiro Tamai, Yusuke Ito, Susumu Takemoto, Yoshitoshi Ogura, Yoshihiro Suzuki","doi":"10.1016/j.envpol.2026.128243","DOIUrl":"10.1016/j.envpol.2026.128243","url":null,"abstract":"<p><p>Escherichia coli is used as an indicator of fecal contamination in river water, yet its geographic variation associated with land use and virulence potential of these strains remain insufficiently characterized. In particular, Shiga toxin (Stx)-producing E. coli (STEC) represents a highly virulent subset capable of causing severe human diseases, while its quantification and virulence assessment are hindered by low abundance in river water. Fixed-point sampling at 10 stations in the Oyodo River, Japan, revealed E. coli counts reaching up to 1.70 × 10⁴ CFU/100 mL and correlating positively with water quality parameters. The counts spiked in residential areas lacking sewer systems and adjacent livestock farms. Four stations where segments characteristics changed were investigated for STEC using the foam concentration method. STEC strains were detected at all locations, with a maximum of 3.98 cells/100 mL, and 13 isolates were recovered, with higher levels downstream of unsewered residences and livestock farms. Given the low infectious dose of STEC, this concentration indicates potential human infection risk. Whole-genome sequencing (WGS) revealed that three isolates (O103:H2 or O111:H8) harbored stx1a and/or stx2a with eae, a combination linked to severe human infections. Ten isolates, including the two stx2a- and eae-positive strains, exhibited multidrug resistance genotypically and phenotypically. WGS of 219 non-STEC E. coli strains isolated across sampling periods revealed consistent shifts in phylogenetic diversity and antimicrobial resistance gene profiles after the river passed through unsewered residences and livestock farms, suggesting persistent contamination. Overall, combining efficient concentration strategies with genome-based analyses enables robust evaluation of STEC occurrence, virulence, and contamination sources in human-impacted river environments.</p>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":" ","pages":"128243"},"PeriodicalIF":7.3,"publicationDate":"2026-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147808974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Liver steatosis induced by per- and polyfluoroalkyl substances exerts a limited influence on heterocyclic aromatic amine-mediated DNA damage at population-relevant exposure levels.","authors":"Minna A Choi, Frédéric Ezan, Matthieu Masaoudi, Etienne B Blanc, Sophie Langouët","doi":"10.1016/j.envpol.2026.127975","DOIUrl":"10.1016/j.envpol.2026.127975","url":null,"abstract":"<p><p>The human population is chronically exposed to complex mixtures of environmental contaminants. However, classical toxicological risk assessment still relies mainly on individual compound testing, often at high concentrations and over short treatment durations that poorly reflect real-life exposure. In this study, we investigated per- and polyfluoroalkyl substances (PFAS) and heterocyclic aromatic amines (HAA) mixtures at concentrations aligned with human serum measurements using mechanistic knowledge of each compound. To evaluate mixture effects, we employed Hepoid®, a 3D human liver model composed of polarized, proliferative, metabolically active, and highly differentiated HepaRG cells for long-term cultures. At human population internal exposure levels, PFAS and HAAs, alone or in combination, induced steatosis measured by automated lipid droplet quantification along with early transcriptional stress responses, without increased DNA damage under mixture conditions, as assessed by 3 complementary genotoxicity and mutagenesis assays (comet assay, γH2AX immunolabelling and micronucleus assay). Overall, this study highlights the importance of concentrations, treatment duration and human-relevant metabolic competence in determining toxic outcomes. By reproducing realistic exposure scenarios in an advanced human liver model sensitive to low-dose mixture effects, this work contributes to improving human relevance of chemical risk assessment.</p>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":" ","pages":"127975"},"PeriodicalIF":7.3,"publicationDate":"2026-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147490393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dual-transformed CuO nanoparticles modulate plant nutrition and stress physiology in copper-starved plants.","authors":"Mikołaj Feculak, Anna Ziarkowska, Houssame-Eddine Ahabchane, Kevin J Wilkinson, Melanie Kah, Jason C White, Izabela Jośko","doi":"10.1016/j.envpol.2026.128009","DOIUrl":"10.1016/j.envpol.2026.128009","url":null,"abstract":"<p><p>Both Cu deficiency and excess impair plant growth, complicating Cu fertilization and raising concerns regarding environmental safety. CuO engineered nanoparticles (ENPs) have been proposed as alternative Cu delivery systems; however, their benefits and potential hazards depend strongly on transformation processes occurring in environmental compartments. Here, we investigated how chemical (sulfidation), biological (protein corona formation), and combined transformations modify the behavior, bioavailability, and plant impacts of pristine CuO ENPs (1-50 mg Cu L^-1) in Hordeum vulgare L. Plant Cu accumulation, mineral nutrient homeostasis, photosynthetic pigment content, and oxidative stress markers were assessed. Both pristine and transformed CuO ENPs increased root Cu concentrations by 5-200-fold, with sulfidation reducing and protein corona formation enhancing Cu uptake. Shoot Cu accumulation was highest for sulfidized CuO ENPs (1.3-4-fold higher than pristine CuO), but remained substantially lower than for ionic Cu, indicating distinct uptake and translocation pathways. Transformations that enhanced ENP dissolution induced stronger perturbations of mineral nutrient balance and elevated reduced glutathione levels (1.2-3.5-fold), reflecting increased metal stress. In contrast, less soluble ENPs preferentially stimulated photosynthetic pigment accumulation and lipid peroxidation (1.4-5-fold), suggesting indirect oxidative responses associated with altered Cu availability rather than direct toxicity. Importantly, protein corona formation on sulfidized CuO ENPs attenuated excessive Cu²⁺ release and moderated nanoparticle-plant interactions, resulting in reduced physiological disruption. Overall, these findings demonstrate that transformation-dependent processes govern Cu bioavailability, plant responses, and hazard potential of CuO ENPs, underscoring the need to incorporate realistic transformation scenarios into environmental risk assessment of nano-enabled agrochemicals.</p>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":" ","pages":"128009"},"PeriodicalIF":7.3,"publicationDate":"2026-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147519357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Occurrence of microplastics across tissues in North Atlantic fin whales (Balaenoptera physalus).","authors":"Giulia Vitale, Marc Ruiz-Sagalés, Valerie Chosson, Sverrir D Halldórsson, Asunción Borrell, Alex Aguilar, Guðjón M Sigurðsson, Fabiana Corami, Carlo Barbante, Odei Garcia-Garin","doi":"10.1016/j.envpol.2026.128026","DOIUrl":"10.1016/j.envpol.2026.128026","url":null,"abstract":"<p><p>As long-lived filter-feeders, baleen whales integrate and reflect changes in ocean contamination, including exposure to microplastics (MPs). This study reports the occurrence of MPs in multiple tissues of North Atlantic fin whales (Balaenoptera physalus) collected off southwestern Iceland in 2023. Five tissues (blubber, muscle, liver, lung, and kidney) from eight individuals were analyzed using the Micro-FTIR and Micro-Raman spectroscopy under strict contamination control. MPs occurred in 32.5% of the samples (13/40; n = 16 particles), predominantly as blue fragments (75%) with an average length of 67.2 ± 33.8 μm. Polyester, polyethylene, and polypropylene were the most common polymers. Although overall tissue differences were minimal, blubber contained the highest MP abundance and longer average particles than other tissues. These findings provide evidence of MP tissue-specific accumulation within a mysticete species and highlight the need to clarify the mechanisms and implications of MP accumulation in marine megafauna.</p>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"397 ","pages":"128026"},"PeriodicalIF":7.3,"publicationDate":"2026-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147571641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retraction notice to 'Aluminum: A potentially toxic metal with dose-dependent effects on cardiac bioaccumulation, mineral distribution, DNA oxidation and microstructural remodeling' [Environ. Pollut. 242, Part A (2018) 814-826].","authors":"Rômulo D Novaes, Viviane G S Mouro, Reggiani V Gonçalves, Andrea A S Mendonça, Eliziária C Santos, Maria C Q Fialho, Mariana Machado-Neves","doi":"10.1016/j.envpol.2026.127913","DOIUrl":"10.1016/j.envpol.2026.127913","url":null,"abstract":"","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":" ","pages":"127913"},"PeriodicalIF":7.3,"publicationDate":"2026-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147442179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aromatic Amine Fingerprints of Human Activities from Indoor Environments - Insights from Textile Analysis.","authors":"Anna Goellner, Tomisin I Babalola, Özge Edebali, Lisa Melymuk, Martin Krauss, Werner Brack, Branislav Vrana, Melis Muz","doi":"10.1016/j.envpol.2026.128293","DOIUrl":"https://doi.org/10.1016/j.envpol.2026.128293","url":null,"abstract":"<p><p>Aromatic amines (AAs), many of which are suspected/known mutagens, are generated in indoor environments by human activities such as smoking tobacco, meat frying and hair dying. Through sorption to textiles followed by desorption during laundry washing they may reach the water cycle and adjacent surface waters, where they contribute to mutagenicity and other adverse effects. In this study, we obtained chemical fingerprints of AAs from textiles linked with different indoor activities. Three different types of fabrics (cotton, polyester and wool) were exposed in smoking pubs, hair salons, restaurant kitchens and households. We analysed the textile samples with a newly developed multitarget extraction and LC-HRMS method. 22 out of 52 target AAs could be detected. Large differences in AA concentrations were observed between the different indoor environments. Among the three different fabrics per site, wool accumulated the highest concentrations of AAs. Generally, the AA concentrations were highest in the smoking pubs, followed by restaurant kitchens, while hair salons and households showed similar concentrations. The compounds predominantly observed were 4-aminodiphenylamine and the known mutagens 2,4-diaminotoluene, 5-amino-o-cresol, o-anisidine, 2-aminopyridine, and the co-mutagenic carboline harman. This observation indicates a potential risk to human health from indoor contamination and shows a potential route for AAs to surface waters after being adsorbed onto textiles and subsequent laundering, posing a risk to aquatic ecosystems. Additionally, mutagenic AAs that are unique to specific locations could be observed, 4-chloro-o-toluidine in hair salon samples and 4-aminobiphenyl in smoking pub samples.</p>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":" ","pages":"128293"},"PeriodicalIF":7.3,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147855580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"OH-Initiated Oxidation of N-Methyl-2-Pyrrolidone: Kinetics, Environmental Fate, and Implications for Biological Interactions.","authors":"Huy D Nguyen, Loc T Nguyen, Tam V-T Mai, Tho H Ho, Thinh T Q Le, Linh H Nguyen, Lam K Huynh","doi":"10.1016/j.envpol.2026.128290","DOIUrl":"https://doi.org/10.1016/j.envpol.2026.128290","url":null,"abstract":"<p><p>N-Methyl-2-pyrrolidone (NMP) is an industrial solvent of global concern due to its widespread use and potential toxicity; however, its atmospheric and aqueous transformation pathways remain poorly understood. In this study, we present the first comprehensive investigation of the reaction between NMP and OH radicals in both gas and aqueous phases over a wide range of conditions (200-2000 K, 0.76-760,000 Torr). High-level electronic structure calculations [CCSD(T)/cc-pVTZ//M06-2X/aug-cc-pVTZ] combined with stochastic RRKM-master equation modeling provided validated rate coefficients and product branching ratios, in good agreement with available experimental data. We demonstrate that NMP degrades rapidly in the atmosphere (lifetime ≈ approximately 12 hours) but persists in water (lifetime ranging from days to decades), highlighting contrasting environmental behaviors. Under ambient conditions, the dominant products are (2-oxopyrrolidin-1-yl)methyl (P4) in air and both P4 and 1-methyl-5-oxopyrrolidin-2-yl (P3) in water. These intermediates further transform into N-formylpyrrolidinone (FP) and N-methylsuccinimide (NMS), which we identify as long-range transported atmospheric products. Molecular docking and dynamics simulations reveal that FP and NMS, unlike NMP, exhibit stronger and more persistent interactions with bromodomain proteins (BRD4), suggesting unrecognized risks to developmental and reproductive health. By integrating quantum chemical kinetics, atmospheric fate modeling, and biological interaction analysis, this work provides new insights into the persistence and potential health impacts of NMP and its degradation products, informing risk assessment and regulatory considerations for this widely used solvent.</p>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":" ","pages":"128290"},"PeriodicalIF":7.3,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147855564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Distribution, sources, and transport pathways of atmospheric gaseous elemental mercury: interhemispheric differences during a transatlantic cruise from the Baltic Sea to the Southern Ocean in 2019-2020.","authors":"Viktor Kalinchuk","doi":"10.1016/j.envpol.2026.128287","DOIUrl":"https://doi.org/10.1016/j.envpol.2026.128287","url":null,"abstract":"<p><p>Mercury is a global pollutant of concern due to its persistence, long-range transport, and neurotoxicity. Understanding its distribution in remote marine environments is essential for assessing international emission controls. Atmospheric gaseous elemental mercury (GEM) was measured continuously during an expedition from the Baltic Sea to the Southern Ocean (December 2019 - May 2020). Concentrations ranged from 0.80 to 2.06 ng/m³, with an overall mean of 1.10 ± 0.16 ng/m³ (N=2916). A significant interhemispheric gradient was observed: Northern Hemisphere mean (1.27 ± 0.11 ng/m³) was substantially higher than that in the Southern Hemisphere (1.00 ± 0.07 ng/m³). A sharp transition across the Intertropical Convergence Zone (0.20-0.22 ng/m³ per degree) highlighted its role as an atmospheric barrier. Both hemispheric means were lower than 1990s measurements, consistent with global declining trends reported in previous studies. Backward trajectory and Concentration-Weighted Trajectory analyses identified key source regions. In the Northern Hemisphere, elevated concentrations were associated with air masses from Western Europe and North America, suggesting transatlantic transport. Elevated values over West Africa were likely linked to artisanal gold mining and biomass burning. In the Southern Hemisphere, coastal South America emerged as a significant source, with probable contributions from Amazonian artisanal mining, urban activities, and deforestation-related burning. Episodic fluctuations were consistently associated with changes in air mass origin.</p>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":" ","pages":"128287"},"PeriodicalIF":7.3,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147855572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The joint and interactive effects of household income, delivery mode with prenatal BPA exposure on offspring early postnatal growth trajectories: A prospective cohort study.","authors":"Yanwei Su, Jinjin Guo, Yaqi Zhu, Yuqi Wang, Keqin Liu, Jixin Yang, Jianli Wu, Zhiliang Chen, Huan Guo","doi":"10.1016/j.envpol.2026.128292","DOIUrl":"https://doi.org/10.1016/j.envpol.2026.128292","url":null,"abstract":"<p><p>This study aims to explore the association between prenatal bisphenol A (BPA) exposure and the offspring's BMI for age z-score (BAZ) trajectories from 0 to 3 months, and to analyze the potential influences of household income and delivery mode. In a prospective cohort of 997 mother-infant pairs, maternal urinary BPA was measured in late pregnancy, and infants were followed up at 1 and 3 months after birth. Mixed linear model showed that prenatal BPA exposure was negatively associated with average BAZ levels in offspring aged 0-3 months. Group-based trajectory model (GBTM) identified three BAZ trajectory patterns: low, moderate, and high growth. Although prenatal BPA exposure was not associated with BAZ trajectories in the overall population, subgroup analyses suggested heterogeneity by household income and delivery mode. BPA exposure was associated with an increased risk of low-growth trajectory in infants from low-income families. Moreover, BPA exposure increased high-growth trajectory risk in the vaginal delivery group but showed an opposite trend in the cesarean delivery group. A significant multiplicative interaction between BPA exposure and delivery mode was observed for the high-growth trajectory. These findings indicate that prenatal BPA exposure is negatively associated with overall BAZ levels during the early infancy, and its association with the risk of low/high BAZ trajectories varies by household income and delivery mode. Furthermore, BPA exposure takes joint and interactive effects with delivery mode on the BAZ trajectory; low BPA exposure and cesarean delivery could significantly increase the risk of a high-growth trajectory.</p>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":" ","pages":"128292"},"PeriodicalIF":7.3,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147855529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PM_2.5 constituents and hospitalizations of full-spectrum cardiovascular diseases: a national case-crossover study.","authors":"Dawei Lv, Ziwei Peng, Yixuan Jiang, Yi Guo, Yuan Liu, Fuchao Wang, Yixiang Zhu, Lu Zhou, Renjie Chen, Jianwei Xuan, Cong Liu, Haidong Kan","doi":"10.1016/j.envpol.2026.128278","DOIUrl":"https://doi.org/10.1016/j.envpol.2026.128278","url":null,"abstract":"<p><p>Multicenter evidence remains limited regarding the short-term impacts of fine particulate matter (PM_2.5) constituents on specific cardiovascular disease (CVD) outcomes. This study assessed the short-term links between PM_2.5 chemical constituents and CVD hospitalizations in China. Hospitalization data for ten broad categories and 40 cause-specific CVD outcomes were collected from 153 hospitals across 20 provinces in China during 2013-2020. A time-stratified case-crossover design was applied. Five major constituents of PM_2.5, namely black carbon, organic matter, sulfate, nitrate, and ammonium, were extracted from the Tracking Air Pollution datasets. PM_2.5 and its constituents were associated with higher hospitalization risk for six CVD categories: hypertensive diseases, ischemic heart diseases, pulmonary heart diseases, cerebrovascular diseases, diseases of veins, and other types of heart diseases. The largest effect estimates were observed on lag 0-1 day, ranging from 0.72% to 4.87% per interquartile range increase in PM_2.5 constituents. Significant associations were also observed for 15 specific causes of CVDs. OM, SO₄^2-, and NO₃^- generally showed larger effect estimates than the other constituents. The concentration-response curves exhibited mostly positive trends. Associations were stronger in males, elderly people, and during cold seasons. This nationwide study offers insights into the effects of PM_2.5 constituents on CVD hospitalization, highlighting the necessity for targeted control of these PM_2.5 constituents.</p>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":" ","pages":"128278"},"PeriodicalIF":7.3,"publicationDate":"2026-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147831770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}