Environmental Pollution最新文献

{"title":"Tracking antibiotics and antibiotic-resistant E. coli in the aquatic environment linked to agriculture","authors":"Laurens Tuts ,&nbsp;Marc Heyndrickx ,&nbsp;Ilse Becue ,&nbsp;Nico Boon ,&nbsp;Philippe De Maesschalck ,&nbsp;Geertrui Rasschaert","doi":"10.1016/j.envpol.2025.126265","DOIUrl":"10.1016/j.envpol.2025.126265","url":null,"abstract":"<div><div>The application of manure to fertilize agricultural land is associated with the introduction of antibiotic residues and bacteria, including antibiotic-resistant bacteria, which can reach surface water through runoff and drainage and groundwater through leaching from the soil. This was investigated by sampling 50 surface water locations (before and after fertilization) and 50 groundwater wells for the presence of antibiotic residues and the presence of antibiotic-resistant bacteria. For the latter, <em>Escherichia coli</em> and extended-spectrum β-lactamase (ESBL) producing <em>E. coli</em> were used as indicators and profiled for antibiotic resistance. The presence of a wide range of antibiotic residues, though at low concentrations (0.01–10 μg/L), in freshwater ecosystems highlights the extensive spread of these substances. Only 16 % of the samples were consistently free of antibiotic residues throughout both sampling periods. Notably, the frequent occurrence of sulfonamides and lincomycin in surface waters raises concerns as their concentrations occasionally exceed the predicted no-effect levels for antimicrobial resistance selection. Maximum concentrations were reported at 8.83 μg/L and 1.60 μg/L for sulfamethoxazole and lincomycin, respectively. Additionally, resistance patterns in <em>E</em>. <em>coli</em> indicate increased resistance to sulfamethoxazole following the fertilization period, suggesting that the application of manure on fields contributes to a rise in antibiotic resistance from 20 % to 48 %. Although antibiotic contamination in groundwater is less prevalent, antibiotic resistance remains widespread. In particular, ESBL-producing <em>E. coli</em> exhibit heightened resistance levels, not limited to β-lactam antibiotics. The detection of resistance to critical last-resort antibiotics such as carbapenems and colistin further emphasizes the urgency of addressing antibiotic resistance in environmental contexts. This study highlights the need for continued monitoring and the implementation of legislation to reduce antibiotic pollution and tackle resistance in aquatic ecosystems.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"374 ","pages":"Article 126265"},"PeriodicalIF":7.6,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143846786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex- and age-specific mercury contamination in Central Europe's last gull-billed tern population","authors":"Anna Schnelle ,&nbsp;Markus Risch ,&nbsp;Peter J. Schupp ,&nbsp;Miriam Liedvogel ,&nbsp;Sandra Bouwhuis","doi":"10.1016/j.envpol.2025.126264","DOIUrl":"10.1016/j.envpol.2025.126264","url":null,"abstract":"<div><div>Mercury contamination is a growing threat to ecosystems and wildlife due to its adverse effects on animal physiology and its potential to accumulate in long-lived top predators. Endangered species may be especially vulnerable, requiring contamination assessment at both the population- and individual-level. Between 2022 and 2024, we assessed total mercury (THg) contamination in the last population of gull-billed terns (<em>Gelochelidon nilotica</em>) in Central Europe, known to breed in a heavily mercury-polluted area, by collecting blood samples of adults and chicks. Among adults, THg concentrations were variable, but mostly below toxicity thresholds associated with major adverse health effects. They were higher in males than females, and higher when birds were sampled later in the season, but not related to clutch size. Using longitudinally collected data and a within-subject centering statistical approach, females, but not males, were found to accumulate THg as they aged. Chicks exhibited relatively low THg levels, which varied with age (following a bathtub-shape), but not sex. As such, our study suggests sex-specific mercury accumulation in gull-billed terns at levels that are currently associated with low to moderate health effects. We recommend continued monitoring of THg levels and assessing the levels of further contaminants, as well as how they may interact with mercury to affect the birds.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"374 ","pages":"Article 126264"},"PeriodicalIF":7.6,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143841855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations of exposure to arsenic species and endogenous sex hormones with oral cancer: a hospital-based study in Southeastern China","authors":"Na Wang ,&nbsp;Wenting Zhang ,&nbsp;Haoyuan Song ,&nbsp;Weihai Huang ,&nbsp;Fa Chen ,&nbsp;Fengqiong Liu ,&nbsp;Yulan Lin ,&nbsp;Yu Qiu ,&nbsp;Bin Shi ,&nbsp;Lisong Lin ,&nbsp;Jing Wang ,&nbsp;Baochang He","doi":"10.1016/j.envpol.2025.126259","DOIUrl":"10.1016/j.envpol.2025.126259","url":null,"abstract":"<div><div>The effects of arsenic species and endogenous sex hormones on oral cancer risk, particularly their molecular interactions, have been infrequently reported. This study aimed to assess the individual and combined effects of arsenic species and endogenous sex hormones on oral cancer risk and elucidate the association between hormones, arsenic species, and arsenic metabolism. A case-control study (comprising 144 cases and 144 controls) was conducted from January 2020 to January 2024 in Southeastern China. Serum levels of six arsenic species and nine endogenous sex hormones were measured using High-Performance Liquid Chromatography Inductively Coupled Plasma Mass Spectrometry (HPLC-ICP-MS) and ultra-high performance liquid chromatography-high resolution mass spectrometry (UPLC-HRMS), respectively. After adjusting for potential confounders, Logistic regression showed that high exposure levels of inorganic arsenic (IAs) (adjusted OR [aOR] and 95 %CI: 0.00[0.00,0.44] and 0.45[0.25,0.78]) and Cortisone (aOR and 95 %CI: 0.16[0.07,0.35] and 0.19[0.10,0.37]) were associated with reduced oral cancer risk, both as continuous and categorical variables. Serum Melatonin, Cortisone, and Testosterone levels correlated with partial arsenic species, while Cortisone and Melatonin were linked to arsenic methylation metabolic indexes (spearman's test <em>P</em> &lt; 0.05). Quantile g-computation analysis revealed that Corticosterone and Cortisone had the largest positive and negative weights on oral cancer risk, respectively (weights = 0.640 and 0.525). The combined effect of arsenic species and hormones on oral cancer was protective (β and 95 %CI: 0.36(-0.05,-0.67)), with slight gender differences. Independent of other arsenic species and hormone levels, Cortisone exhibited a protective effect against oral cancer in BKMR analysis. Additionally, an interaction effect between Melatonin and other arsenic species was also observed. In summary, Serum IAs and Cortisone were negatively associated with oral cancer, while Corticosterone showed a positive association. Further cohort studies are needed to confirm and elucidate these mechanisms.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"374 ","pages":"Article 126259"},"PeriodicalIF":7.6,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143841893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect and mechanisms of nano cerium dioxide (Nano-CeO2) on cardiovascular development in zebrafish (Danio rerio)","authors":"Yiyun Liu ,&nbsp;Yan-Ling Liao ,&nbsp;Jin-Xia Wang,&nbsp;Bao-Fu Zhang,&nbsp;Qi-Ping Tang,&nbsp;Yuan Ding,&nbsp;Si-Jia Zuo,&nbsp;Qin-Hong Zhou,&nbsp;De-Sheng Pei","doi":"10.1016/j.envpol.2025.126268","DOIUrl":"10.1016/j.envpol.2025.126268","url":null,"abstract":"<div><div>The widespread application of nano-cerium dioxide (Nano-CeO₂) in agriculture, industry, and other fields has led to an increasing amount of it being released into the environment and becoming a pollutant with potential biological hazards. However, studies on the effects of ceria on cardiovascular development were limited. This study aims to detect the cardiovascular toxicity of Nano-CeO₂, focusing on its impact on zebrafish hematopoietic function and cardiac development, and to explore its potential molecular mechanisms. We found that exposing zebrafish embryos to different concentrations of Nano-CeO₂ after 6 hpf of fertilization does not hinder the growth and development of zebrafish embryos during their early life stages. However, RNA-Seq analysis indicated that the gene expression related to zebrafish hematopoiesis was significantly downregulated, and the ECM-receptor interaction pathway was disrupted.The results of o-dianisidine staining, neutral red staining, and Sudan black staining showed that the hemoglobin, macrophages, and neutrophils of zebrafish were reduced, and the vascular dysplasia of zebrafish was observed. Meanwhile, Reactive oxygen species (ROS) accumulated in the heart of zebrafish larvae treated with Nano-CeO₂, and heart development-related genes (<em>nppa</em>, <em>hand2</em>, <em>nppb</em>, <em>nkx2.5</em>, and <em>myh7</em>) were significantly down-regulated, while <em>gata4</em> was up-regulated. The addition of the integrin agonist manganese ions restored the expression of genes related to ECM-receptor interaction pathways, alleviating cardiovascular abnormalities caused by Nano-CeO₂. Besides, significant changes in cardiac histopathology were observed with long-term exposure (120 d post-fertilization), indicating that Nano-CeO₂ exposure affected the development of the cardiovascular system in zebrafish. In summary, acute and chronic exposure to Nano-CeO₂ exhibits cardiovascular toxicity in zebrafish, affecting hematopoietic function and cardiac development, and the mechanism may be related to the ECM-receptor interaction pathway. This study provides useful information for a comprehensive understanding of the toxicity mechanisms and environmental risks of Nano-CeO₂.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"374 ","pages":"Article 126268"},"PeriodicalIF":7.6,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143841856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Environmental stress responses to marine mucilage: Oxidative damage in economically important seafood from the Sea of Marmara","authors":"Eda Dagsuyu ,&nbsp;Idil Can-Tuncelli ,&nbsp;Refiye Yanardag ,&nbsp;Nuray Erkan ,&nbsp;Hande Dogruyol ,&nbsp;Safak Ulusoy ,&nbsp;Ozkan Ozden ,&nbsp;Suhendan Mol ,&nbsp;Sehnaz Yasemin Tosun ,&nbsp;Didem Ucok","doi":"10.1016/j.envpol.2025.126266","DOIUrl":"10.1016/j.envpol.2025.126266","url":null,"abstract":"<div><div>Marine mucilage, a gelatinous organic substance driven by nutrient enrichment and rising sea temperature, poses significant threats to marine biodiversity and fisheries. This study examines the oxidative stress responses in four seafood species: deep-water rose shrimp (<em>Parapenaeus longirostris</em>), common sole (<em>Solea solea</em>), European anchovy (<em>Engraulis encrasicolus</em>), and Atlantic horse mackerel (<em>Trachurus trachurus</em>) in Sea of Marmara, Türkiye, between September 2021 to April 2022. Biomarkers of oxidative stress—reduced glutathione (GSH), lipid peroxidation (LPO), and antioxidant enzyme activities (glutathione reductase, glutathione-S-transferase, and superoxide dismutase), were analyzed in muscle tissues to evaluate species-specific resilience to mucilage. Findings revealed distinct variations among species. Deep-water rose shrimp demonstrated the highest GSH level and lowest LPO level, indicating robust oxidative stress defense. In contrast, pelagic species, including European anchovy and Atlantic horse mackerel, exhibited decreased GSH and elevated LPO levels and variability antioxidant enzyme activities, reflecting greater sensitivity to environmental stress. During the marine mucilage, in addition to mucilage distribution, fluctuations in seawater temperature (between 7.4°C and 24.4°C), and physiological stress caused seasonal changes in various enzymatic activities of the fish species investigated in our study. These results highlight the risks posed by marine mucilage to seafood safety and the ecological balance of marine environments. The vulnerability of pelagic species, combined with their economic and nutritional importance, underscores the urgency of mitigation strategies. This study emphasizes the need for integrated “One Health” approaches to safeguard ecosystem health and food security in the region.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"374 ","pages":"Article 126266"},"PeriodicalIF":7.6,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143841886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The plastic size spectra: Assessing the size structure of plastic particles across the land-water ecotone","authors":"Scott F. Collins,&nbsp;Andrea Norton","doi":"10.1016/j.envpol.2025.126263","DOIUrl":"10.1016/j.envpol.2025.126263","url":null,"abstract":"<div><div>Plastics of different types and sizes pollute most of Earth's environmental systems. Here, we used size spectra analysis (SSA) to evaluate and characterize size-frequency patterns of plastic pollution across the land-water ecotone of 20 urban lakes. We first tested the general hypothesis that plastic particles in the environment reflect a detectable and inverse size-frequency pattern as large plastics regularly breakdown in increasingly smaller pieces. To further evaluate the utility of SSA, we tested whether slope (λ) and intercept (Γ) coefficients from lake-specific models were sensitive to distinguish trends among lake zones. Overall, our findings detected an overall inverse relationship between particle counts (#/m²) and binned particle length, confirming the presence of a plastic size spectra for all aggregated data. We further improved the explanatory power of SSA models by (1) separating thin films from thicker plastic fragments and by (2) assessing sampling environments (i.e., upland vegetation, shoreline sediments, offshore sediments) separately. Doing so revealed statistically distinct size-frequency gradients that tracked the shift from land to water for both films and fragments. Analysis and comparison of SSA models also confirmed that coefficients were sensitive enough to detect differences among lake zones. All told, the SSA framework was successfully used to detect and describe several patterns of plastic pollution in the environment. This analytic framework holds promise for developing hypothesis-driven studies to all plastics rather than focusing on small or large particles.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"374 ","pages":"Article 126263"},"PeriodicalIF":7.6,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143841857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Elevated temperature magnifies the toxicity of imidacloprid in the collembolan, Folsomia candida","authors":"Lelin You ,&nbsp;Ming Gao ,&nbsp;Christian Damgaard ,&nbsp;Dong Zhu ,&nbsp;Yifei Wang ,&nbsp;Naichuan Xiao ,&nbsp;Tingting Zhang ,&nbsp;Zifang Wang ,&nbsp;Wencai Dai","doi":"10.1016/j.envpol.2025.126260","DOIUrl":"10.1016/j.envpol.2025.126260","url":null,"abstract":"<div><div>Global warming subjects soil organisms to elevated temperature stress, while simultaneously altering the detoxification processes for pollutants within these organisms. The combined stressors of increased temperature and pollutants may impose synergistic stress on soil fauna, necessitating detailed investigation. Here, we exposed Collembola (<em>Folsomia candida</em>) to imidacloprid (a neonicotinoid pesticide) in combination with a range of constant temperatures in a full-factorial experimental design to assess the integrated impacts on survival, growth, and bioaccumulation. The results revealed that high temperatures and imidacloprid synergistically inhibited the survival of <em>F. candida</em>. Under 6<strong>.</strong>4 mg/kg imidacloprid exposure, survival rates decreased by 41.38 % at 30.2 °C and 68.75 % at 30.5 °C, compared to the same temperature treatments without imidacloprid exposure. Bayesian model analysis confirmed a significant synergistic interaction between imidacloprid and temperature on survival. Interestingly, at elevated temperatures, the internal concentration of imidacloprid in <em>F. candida</em> significantly decreased, while the soil concentration of the insecticide remained stable. This suggests that the observed synergistic effect is not due to increased pollutant accumulation within <em>F. candida</em> at higher temperatures, but rather the exhaustion of energy resources needed for detoxification and thermal stress management. This dual-stressor-induced energy competition underpins the synergistic interactions observed. Our findings highlight the significant synergistic effects of high temperatures and imidacloprid on Collembola, underscoring an increased ecological risk under such conditions.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"374 ","pages":"Article 126260"},"PeriodicalIF":7.6,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143841858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Facile synthesis of urea-modified sewage sludge biochar for efficient sulfamethoxazole degradation via an electron transfer pathway","authors":"Yingjian Yu ,&nbsp;Yulong Li ,&nbsp;Jingyue Bao ,&nbsp;Zhuqi Chen ,&nbsp;Longhua Wu ,&nbsp;Lie Yang","doi":"10.1016/j.envpol.2025.126256","DOIUrl":"10.1016/j.envpol.2025.126256","url":null,"abstract":"<div><div>The widespread presence of antibiotic residues in environmental matrices poses significant ecological risks. In this study, N-doped sludge biochar (NSBC) was synthesized through a straightforward and practical method using waste activated sludge and urea. The synthesized NSBC was employed to activate periodate (PI) for the efficient removal of sulfamethoxazole (SMX) from aqueous solutions. The incorporation of urea markedly enhanced the biochar's adsorption capacity and catalytic oxidation performance, achieving complete SMX removal within 60 min, while maintaining high removal efficiency across wide pH conditions (3–9). Interference experiments revealed that common anions (Cl⁻, SO₄²⁻, and NO₃⁻) exerted minor inhibitory effects on SMX removal, while the presence of humic acid and the complex matrices of three natural water systems maintained SMX removal efficiencies above 70 %. Quenching experiments, electron paramagnetic resonance, and electrochemical analyses confirmed that the degradation of SMX primarily occurs via a non-radical pathway facilitated by an electron transfer mechanism. Analysis of degradation products and predictions from the ECOSAR model suggested that SMX was transformed into a series of smaller, low-toxicity intermediate products, significantly diminishing its inhibitory effect on seed germination. This study offers a sustainable strategy for waste sludge valorization and an eco-friendly solution for antibiotic pollution mitigation.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"374 ","pages":"Article 126256"},"PeriodicalIF":7.6,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143831712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Properties of inflowing Pacific and Atlantic water govern total and methylated mercury profiles in the Arctic Ocean","authors":"Sangwoo Eom ,&nbsp;Anne L. Soerensen ,&nbsp;Tae Siek Rhee ,&nbsp;Jong Kuk Hong ,&nbsp;Purena Son ,&nbsp;Tae Keun Rho ,&nbsp;Seunghee Han","doi":"10.1016/j.envpol.2025.126254","DOIUrl":"10.1016/j.envpol.2025.126254","url":null,"abstract":"<div><div>High methylmercury (MeHg) concentrations in Arctic marine biota have been linked to high MeHg uptake driven by shallow MeHg peaks at water depths of 100–300 m in the Arctic Ocean. To understand how the biogeochemical characteristics of each basin affects the distribution of total Hg (THg) and MeHg across the Arctic Ocean, the spatial patterns of THg and MeHg were investigated using data from new transects in the Beaufort Sea (BS) and previously published Arctic Ocean expeditions covering the Canada Basin and Makarov Basin in the Pacific sector, and Amundsen Basin and Nansen Basin in the Atlantic sector. In the BS, the THg concentration in the polar mixed water increased with salinity (r = 0.87, p &lt; 0.01), which was linked to THg transport from the Chukchi Shelf. Transport of Hg from the Chukchi Shelf also drove elevated THg concentrations in the polar mixed water and halocline water in the Canada Basin and Makarov Basin compared to other Arctic basins. The MeHg concentration in the BS was positively correlated with the biological index in the Pacific summer water (r = 0.86, p &lt; 0.01), demonstrating that intrusion of warm and nutrient-rich Pacific water promotes MeHg production in the BS. In line with this result, chlorophyll-a showed a comparable cross-basin trend to that of MeHg, with the highest values in the Nansen Basin. In the halocline water, MeHg concentrations were highest in the Canada Basin likely due to the largest availability of Hg(II). On the contrary, MeHg concentration was highest in the Nansen Basin in the Atlantic water layer, which could be related to the higher seawater temperature and enhanced biological production. The results of this study underscore the critical role of Pacific and Atlantic inflows in modulating the profiles of THg and MeHg in the Arctic Ocean.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"374 ","pages":"Article 126254"},"PeriodicalIF":7.6,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143831766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of human exposure to uncommon industrial toxicants in Glynn County, Georgia","authors":"Noah Scovronick ,&nbsp;Brooke Lappe ,&nbsp;Melanie A. Pearson ,&nbsp;Katy A. Smith ,&nbsp;Stephanie M. Eick ,&nbsp;Priya E. D'Souza ,&nbsp;Parinya Panuwet ,&nbsp;Minghao Kong ,&nbsp;Volha Yakimavets ,&nbsp;Rylee Stephenson ,&nbsp;Dana Boyd Barr","doi":"10.1016/j.envpol.2025.126240","DOIUrl":"10.1016/j.envpol.2025.126240","url":null,"abstract":"<div><div>Coastal Glynn County, Georgia, is home to four hazardous sites on the United States EPA's National Priorities List. Toxicants of concern include mercury, the pesticide toxaphene, and Aroclor 1268, a mixture of highly chlorinated polychlorinated biphenyls (PCBs); these toxicants are known to persist in the local environment and/or regional aquatic life, including local seafood. At the invitation of, and in partnership with, local community leaders and environmental groups, we conducted a human exposure study in Glynn County. The average age of the study participants was 61 years, 66 % were female, and 46 % were Black. Mercury levels in study participants were comparable to the general US population. Levels of less chlorinated PCBs (PCB 118, 138, 153 and 180) were lower in participants compared to the general population, but the highly chlorinated PCBs associated with Aroclor 1268 were elevated; 19.3 %, 25.0 % and 39.8 % of participants were above the estimated 95th percentile reference values for PCBs 196 + 203, 199, and 206, respectively. About 20 % of participants were above the 95th percentile reference level for both toxaphene Parlars tested (Parlars 26 and 50). We also report on several other toxicants including other metals (lead and cadmium), p,p’-DDE, and poly- and per-fluorinated alkyl substances (PFAS). This study provides evidence that toxicants associated with local hazardous sites have contributed to exposures in Glynn County residents, and that some residents have exposures far exceeding what is common in the general population.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"375 ","pages":"Article 126240"},"PeriodicalIF":7.6,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143831765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}