Environmental Pollution最新文献

{"title":"Diesel particulate matter health impacts in California: Trends, source apportionment, and policy implications","authors":"Shuming Du,&nbsp;Pingkuan Di,&nbsp;XueMeng Chen,&nbsp;Yiting Li,&nbsp;Yunle Chen,&nbsp;Karry Liu,&nbsp;Zhen Liu,&nbsp;Abdullah Mahmud,&nbsp;Melissa Venecek,&nbsp;Daniel Chau,&nbsp;Wenli Yang,&nbsp;Roger Kwok,&nbsp;Leonardo Ramirez,&nbsp;Jeremy Avise","doi":"10.1016/j.envpol.2025.127182","DOIUrl":"10.1016/j.envpol.2025.127182","url":null,"abstract":"<div><div>Diesel particulate matter (DPM) has been recognized as a carcinogen and identified as a toxic air contaminant (TAC) in California and other jurisdictions. In response to this identification, the California Air Resources Board (CARB) has adopted numerous regulations aimed at reducing DPM emissions from various sources. This study utilized an integrated modeling approach to simulate ambient DPM concentrations for individual emission sectors separately for the two years 2012 and 2017. The associated health impacts, including cancer risk and non-cancer effects, were then assessed. This assessment provided a basis for apportioning emission sources, analyzing reduction trends, and informing further regulatory efforts when combined with future emissions projections.</div><div>Our results showed a significant reduction in DPM-related cancer risk in California between 2012 and 2017. Specifically, population weighted DPM cancer risk decreased by 42 %, and mortality attributable to DPM exposure decreased by about 50 % statewide. Additionally, census tracts with higher population densities consistently experienced more significant reductions in DPM cancer risk from 2012 to 2017.</div><div>Source apportionment analysis indicated that, as of 2017, on-road mobile sources were the largest contributor to overall DPM risk, followed by off-road mobile, area, and stationary sources. Our findings further suggest that while the overall health risk from DPM will continue to decline with emissions, the relative contributions of each emission sector to DPM risk may shift over time depending on the major regulations in place, and how the emission reductions impact nearby population. When accounting for how emissions have changed since 2017 and are projected to change in the future, new emission reduction efforts will likely need to prioritize off-road mobile sources (e.g., seaports, airports, locomotives) and area sources (e.g., construction and agricultural sectors) to achieve further risk reductions, especially beyond 2025.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"386 ","pages":"Article 127182"},"PeriodicalIF":7.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145195191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A consortium of Aspergillus species biodegrades polypropylene plastic","authors":"Asma Mudhahi Alshammari ,&nbsp;Promy Virk ,&nbsp;Rasha Elsayim ,&nbsp;Norah Raqi Al-Otaibi ,&nbsp;Alanoud Tariq Al Sudairi ,&nbsp;Manal A. Awad ,&nbsp;Abdel-Basit Al-Odayni ,&nbsp;Dalia Fouad","doi":"10.1016/j.envpol.2025.127179","DOIUrl":"10.1016/j.envpol.2025.127179","url":null,"abstract":"<div><div>In recent times, there has been increased worldwide awareness on the grave issue of plastic pollution, and its ever-increasing peril to the environment. The present study used a consortium of fungus species; <em>Aspergillus niger</em>, <em>Aspergillus flavus</em> and <em>Aspergillus oryzae</em> for the degradation of polypropylene(PP) plastic with and without abiotic pre-treatment(UV, thermal) grown in a carbon rich and carbon free media in laboratory settings. Post 90-day incubation period, the weight loss of PP reached 23.3 % with temperature pre-treatment and 16.66 % in untreated PP. The PP samples showed substantial surface changes compared to the control group. Marked chemical alterations in PP samples were identified on the 10th and 90th day, validated by FTIR and quantified as carbon index(CI) illustrating the oxidative polymer scission. SEM micrographs revealed the particles' frailty and plausible oxidation degree estimated by the atomic O/C ratio corroborated the biodegradative capability of the fungal consortium. Although the presence of a carbon supply enhanced the efficacy, the key finding underlines that this consortium may thrive in both carbon-rich and carbon-starved conditions.</div><div>Additionally, PP could be prospectively degraded by the fungal spp. with/without abiotic pre-treatment, underlining the relevance of biotic process as a sustainable strategy to resolve plastic waste management.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"386 ","pages":"Article 127179"},"PeriodicalIF":7.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145203297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Behavioral and biochemical effects of fluoxetine on Poecilia reticulata: A relaxing state or an unapparent crisis?","authors":"Mohammed Ariful Islam ,&nbsp;Daniel C.V.R. Silva ,&nbsp;Camilo Dias Seabra Pereira ,&nbsp;Caio Rodrigues Nobre ,&nbsp;Fabrini Copetti ,&nbsp;Maria Eduarda Nunes Oliveira Martins Ferreira ,&nbsp;João Vitor Rocha de Freitas ,&nbsp;Paulo Sérgio Marques ,&nbsp;Julián Blasco ,&nbsp;Cristiano V.M. Araújo","doi":"10.1016/j.envpol.2025.127192","DOIUrl":"10.1016/j.envpol.2025.127192","url":null,"abstract":"<div><div>Fluoxetine is an antidepressant used for the treatment of depression and anxiety disorders. We hypothesized that fluoxetine may positively influence the well-being of fish. We used <em>Poecilia reticulata</em> as a model organism and evaluated the behavioral, ecological and biochemical alterations following fluoxetine exposure at 0.05, 2.0, and 80 μg/L. For the behavioral analysis, we assessed swimming patterns, aggressiveness, social interactions and predatory behavior in a novel tank. Avoidance and colonization were evaluated as behavioral endpoints using the non-forced HeMHAS (Heterogeneous Multi-Habitat Assay System) as a novel approach to assess behavioral endpoints. The biochemical approach was based on the biotransformation enzyme activity (EROD and GST), anti-oxidative defense markers (GPx and GSH), oxidative damage indicators (LPO and DNA damage) and neurotoxicity (AChE activity). We found that the swimming patterns, aggressiveness and social behavior were reduced from 2 μg/L (p &lt; 0.001) and the time spent by <em>P. reticulata</em> in the top and bottom areas differed significantly from 0.05 μg/L (p &lt; 0.05). Additionally, organisms exposed to fluoxetine required more time (significantly from 2 μg/L; p &lt; 0.001) to attack all the <em>Daphnia</em> sp. provided as prey. Further, in the colonization and avoidance tests, <em>P. reticulata</em> did not display colonization behavior (50–60 % time spent in the control compartment), and exhibited only weak avoidance responses, instead appearing to be either lethargic or in a relaxing state. The biochemical analysis showed that GST and LPO levels were elevated (p &lt; 0.001), while both the GPx and GSH were reduced (p &lt; 0.05).</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"386 ","pages":"Article 127192"},"PeriodicalIF":7.3,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145188330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EGCG alleviated 2,4-D-induced cardiovascular toxicity in zebrafish embryos via Nrf2 and p53 pathways","authors":"Xuhong Huang ,&nbsp;Weixiang Wang ,&nbsp;Wenwen Zhang","doi":"10.1016/j.envpol.2025.127181","DOIUrl":"10.1016/j.envpol.2025.127181","url":null,"abstract":"<div><div>2,4-Dichlorophenoxyacetic acid (2,4-D), a widely used herbicide in cultivation, exhibits strong cardiotoxicity to living organisms, thus shows high risks to human health. Epigallocatechin gallate (EGCG), a type of catechin largely found in tea, is well-known for its antioxidant, antiapoptotic, and cardiovascular protective properties. Neverthless, the potential protective effects of EGCG against 2,4-D-induced cardiotoxicity remain underexplored to date. In this study, zebrafish embryos were exposed to 50 mg/L 2,4-D supplemented with 2 μM EGCG until 96 h post-fertilization (hpf) and the morphology observation, biochemical assays, and gene expression analyses were applied to evaluate the role of EGCG against 2,4-D toxicity. The results showed that EGCG significantly restored the 2,4-D-induced cardiovascular impairments including pericardial edema, and abnormal heart structure, heart rate and erythropenia. Q-PCR analysis revealed that EGCG markedly reversed the 2,4-D-dysregulated key cardiac development genes <em>nkx2.5</em>, <em>vegf</em>, <em>vmhc</em>, <em>amhc</em>, <em>hand2</em> and <em>gata4</em>, except for <em>tbx2b</em>, which remained unchanged. EGCG also counteracted 2,4-D-induced oxidative stress by elevating antioxidant enzymes activities and nonenzyme antioxidant content, resulting in the reduction of malondialdehyde (MDA) and reactive oxygen species (ROS) in 2,4-D group. Furthermore, EGCG modulated the expression of antioxidant defense-related genes <em>Nrf2</em>, <em>sod1</em>, <em>cat</em>, <em>gpx1a</em> and <em>gstm</em> and mitigated the harsh effects of 2,4-D. Moreover, EGCG effectively inhibited 2,4-D-stimulated cellular apoptosis through down-regulation of pro-apoptotic genes of <em>p53</em>, <em>caspase-9</em>, <em>caspase-3</em> and <em>bax</em> and up-regulation of anti-apoptotic gene <em>bcl-2</em>. In conclusion, EGCG can alleviate 2,4-D-induced cardiovascular toxicity in zebrafish embryos through the <em>nrf2</em>-regulated antioxidant pathway and <em>p53</em>-regulated apoptotic pathway.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"386 ","pages":"Article 127181"},"PeriodicalIF":7.3,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145188795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Size and end-group chemistry of linear polyethylene terephthalate oligomers matter in chemical risk assessment","authors":"Milica Djapovic ,&nbsp;Dragana Stanic-Vucinic ,&nbsp;Tamara Lujic ,&nbsp;Vesna Jovanovic ,&nbsp;Jeanette Grundström ,&nbsp;Tamara Vasovic ,&nbsp;Lukas Wimmer ,&nbsp;Lea Ann Dailey ,&nbsp;Veselin Maslak ,&nbsp;Danijela Apostolovic ,&nbsp;Marianne van Hage ,&nbsp;Tanja Cirkovic Velickovic","doi":"10.1016/j.envpol.2025.127194","DOIUrl":"10.1016/j.envpol.2025.127194","url":null,"abstract":"<div><div>Cyclic and linear oligomers, formed as side-products during PET polymerization, are poorly characterized non-intentionally added substances (NIAS) in food. Risk assessment of PET oligomers is challenging due to their size, number, isomerism, complexity in structure, and lack of analytical standards. The great heterogeneity in size and structure of PET oligomers calls for a systematic approach in risk assessment and hazard identification. The aim of our study was to synthesize and characterize physicochemical properties, protein, DNA and cellular interactions of a series of linear methylated and non-methylated PET oligomers (monomer, dimer and trimer). Our results show striking differences in the properties of PET oligomers in relation to size and end-group chemistry (methylated vs. free carboxyl-vs. free hydroxyl-). Solubility in food simulants decreases with increase in methylation and the number of aromatic rings. Linear PET oligomers show little to no toxicity in a wide range of concentrations tested in primary cells and are taken up by human monocyte derived dendritic cells. All linear PET oligomers tested readily interact with food and serum proteins resulting in large protein/plastic oligomer aggregates. Methylated PET trimers bind to salmon sperm DNA, leading to significant destabilization of the DNA. Our results point to the importance of size and end-group of PET oligomers in chemical risk assessment: size and methylation of the oligomer strongly contribute to the observed cellular and molecular effects of tested compounds. Larger methylated PET oligomer binding to DNA prompts further research on the toxicological relevance of the observed interactions.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"386 ","pages":"Article 127194"},"PeriodicalIF":7.3,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145195192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced mitigation of antibiotic resistance genes in anaerobic digestion of food waste using biochar-supported nanoscale zero-valent iron","authors":"Lang Chen ,&nbsp;Hailin Shao ,&nbsp;Shihao Gong ,&nbsp;Changchao Li ,&nbsp;Ling Jin ,&nbsp;Zifan Huang ,&nbsp;Pan Wang ,&nbsp;Xingyao Meng ,&nbsp;Lianhai Ren","doi":"10.1016/j.envpol.2025.127191","DOIUrl":"10.1016/j.envpol.2025.127191","url":null,"abstract":"<div><div>Food waste (FW) is a crucial biomass resource and reservoir of antibiotic resistance genes (ARGs). Biochar-supported nanoscale zero-valent iron (BC-nZVI) can enhance methane production in the anaerobic digestion (AD) of FW. However, the mechanisms underlying the effects of BC-nZVI on the fate of ARGs during AD are remain unclear. Here, the impacts of BC-nZVI on the fate of total ARGs were investigated, by analyzing dynamics of representative types of ARGs including intracellular and extracellular ARGs (iARGs and eARGs). We found a significant decrease in the abundance of the most ARGs during AD treated with BC-nZVI. Specially, the relative abundance of iARGs (<em>tet32</em>, <em>ermF</em>, <em>sul1</em>, and <em>tetW</em>) decreased by 30.58 %, 11.38 %, 16.69 %, and 3.65 %, respectively, while that of eARGs (<em>tet32</em>, <em>ermF</em>, <em>sul1</em>, and <em>tetW</em>) decreased by 95.09 %, 48.18 %, 88.55 %, and 71.41 %, respectively. The relative abundances of intracellular and extracellular <em>intI1</em> decreased by 17.42 % and 41.96 %, respectively. BC-nZVI enhanced microbial metabolism, prevented SOS response activation, reduced the expression of type IV secretion systems, and decreased extracellular polymeric substance secretion, which could contribute to the decrease in ARGs. These findings indicate that BC-nZVI can effectively mitigate the risk of ARGs in AD by reducing their abundance and inhibiting their horizontal transfer.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"386 ","pages":"Article 127191"},"PeriodicalIF":7.3,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145188331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biomagnification of chlorinated paraffins in amphibians from an e-waste effected ecosystem, South China: evidence from quantitative fatty acid signature analysis","authors":"Hongyan Pan, Yang Ding, Xiaobo Zheng, Zhengjun Wu, Xiaojun Luo, Bixian Mai, Hongjia Li","doi":"10.1016/j.envpol.2025.127187","DOIUrl":"https://doi.org/10.1016/j.envpol.2025.127187","url":null,"abstract":"Amphibians are ecologically significant and environmentally sensitive vertebrates, yet the bioaccumulation behavior and trophic transfer of chlorinated paraffins (CPs) in amphibian remain poorly understood. In this study, we examined the concentrations, tissue distribution, and congener profiles of short- and medium-chain chlorinated paraffins (S/MCCPs) in amphibians and their insect prey from an e-waste-contaminated wetland. Quantitative fatty acid signature analysis (QFASA) was applied to determine amphibians’ dietary composition and to refine biomagnification factor (BMF_QFASA) calculations. Median concentrations of the total CPs were ranged from 1.75 to 38.2 μg/g lipid weight (lw) in amphibian tissues, and ranged from 1.45 to 7.14 μg/g lw in eight insect species. Results showed that S/MCCPs were widely distributed in amphibian tissues, with the highest SCCPs levels found in skin, and MCCPs in muscle. Predator–prey relationships and physiological traits influenced tissue-specific accumulation and interspecies differences in three amphibians. Principal component analysis of CP homologue profiles revealed clustering patterns reflecting trophic transfer, particularly between amphibians and insect taxa such as dragonflies. BMFs of S/MCCP congeners ranged from 0.55 to 11.7, 0.12 to 5.27, and 0.26 to 6.49, respectively, exhibited biomagnification along the amphibian food chains, except for SCCPs in the WF food chain. Log BMF_QFASA showed a parabolic relationship with log <em>K</em>_OW and a strong positive correlation with log <em>K</em>_OA, suggesting that <em>K</em>_OA is a better predictor of biomagnification in amphibians. Our findings provide novel insights into the environmental behavior of CPs in amphibian food chains and highlight the need to consider species-specific traits and physicochemical properties in ecological risk assessments.","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"72 1","pages":""},"PeriodicalIF":8.9,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145195223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Irrigation-introduced quinolone antibiotics activated the soil-water interface redistribution of per- and polyfluoroalkyl substances in paddy fields","authors":"Jianyi Wu ,&nbsp;Xinlin Huang ,&nbsp;Miao Chen ,&nbsp;Lingxuan Li ,&nbsp;Wenhui Zhao ,&nbsp;Wenqing Tu","doi":"10.1016/j.envpol.2025.127193","DOIUrl":"10.1016/j.envpol.2025.127193","url":null,"abstract":"<div><div>Quinolone antibiotic pollution (QAP) introduced by irrigation may cause the release of per- and polyfluoroalkyl substances (PFASs) at the soil-water interface in paddy fields, endangering the growth of rice crops and the security of human food sources. Thus, the comprehensive investigation of the joint and individual effects of quinolone antibiotics with environment-relevant concentrations on the soil PFASs migration were conducted. Results showed that the QAP dose of 1 μg/L had the highest activation for the release of PFASs into the overlying water, resulting in the highest net concentration of 99.32 μg/L. Structural equation modeling revealed that the QAP-mediated microbial adsorption was the hub transition for PFASs migration (<em>p</em> &lt; 0.001). The PFASs re-partitioning after QAP was primarily driven by physicochemistry and nutrient cycling variations induced by QAP, which was facilitated by soil microbial urease and acid phosphatase. The soil microbial genes <em>nasC</em>, <em>nasE</em>, <em>phnG</em>, <em>nasD</em>, <em>napD</em>, <em>phnA</em>, <em>nirK</em>, <em>nosZ</em>, and <em>nasB</em> were identified as the critical regulators of PFASs migration under QAP by the aggregate boosted tree modeling. Molecularly, the soil microbial metabolisms of <em>Galactosylglycerol</em> and <em>3-beta-D-Galactosyl-sn-glycerol</em> were responsible for PFASs release under the QAP level of 1 μg/L (<em>p</em> &lt; 0.001). These findings were beneficial in elucidating the ecological risks of bioavailable PFASs in paddy fields subjected to the integrated pollution of quinolone antibiotics.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"386 ","pages":"Article 127193"},"PeriodicalIF":7.3,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145195222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Per- and polyfluoroalkyl substances (PFAS) disrupt gut microbiome composition and metabolism in metabolic syndrome: Evidence from a host-free in vitro colonic model","authors":"Chao Guo ,&nbsp;Shiqi Zhang ,&nbsp;Huan Zhang ,&nbsp;Li Chen ,&nbsp;Shuaixin Gao ,&nbsp;Mengyang Xu ,&nbsp;Haifei Shi ,&nbsp;Jiangjiang Zhu","doi":"10.1016/j.envpol.2025.127189","DOIUrl":"10.1016/j.envpol.2025.127189","url":null,"abstract":"<div><div>Metabolic syndrome (MetS) is a global health concern linked to metabolic abnormalities and increased risk of type 2 diabetes and cardiovascular disease. Recent studies suggest that exposure to per- and polyfluoroalkyl substances (PFAS) may contribute to MetS through alterations in gut microbiota and metabolism, but the underlying mechanisms remain unclear. This study aimed to investigate the effects of PFAS exposure on gut microbiota composition and metabolism in MetS using a three-stage, automated, computer-controlled <em>in vitro</em> Human Colonic Model (HCM) system. We introduced PFAS exposure to the gut microbiome <em>in vitro</em> at two concentrations (100 ng/mL and 1000 ng/mL) and analyzed microbial community structure using microbiome analysis, while changes in gut microbial metabolism were assessed through targeted and untargeted metabolomics. Our results showed that PFAS exposure significantly altered gut microbiota composition, with notable changes in key genera such as <em>Morganella</em> and <em>Bilophila</em>. Metabolomics analysis revealed an increase in short-chain fatty acid (SCFA) production at 1000 ng/mL of PFAS exposure, as well as significant alterations in other metabolites, including decreased acetophenone and taurocholic acid in both concentrations. These findings suggest that PFAS exposure may disrupt gut microbiota homeostasis and contribute to metabolic disturbances associated with MetS. This study highlights the need for further investigation into the mechanisms underlying PFAS-induced alterations in gut microbiota and their potential impact on human health.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"386 ","pages":"Article 127189"},"PeriodicalIF":7.3,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145188793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of concurrent PFASs and CAHs on microbial communities in soil and groundwater: an insight for their ecological niches and implications for bioremediation","authors":"Xiqian Zhang ,&nbsp;Zhiwen Tang ,&nbsp;Md Golam Kabir ,&nbsp;Qing Wang ,&nbsp;Changxun Dong ,&nbsp;Xin Song","doi":"10.1016/j.envpol.2025.127186","DOIUrl":"10.1016/j.envpol.2025.127186","url":null,"abstract":"<div><div>The combined impacts of per- and polyfluoroalkyl substances (PFASs) and chlorinated aliphatic hydrocarbons (CAHs) on native microbial communities in subsurface remain poorly understood. In this study, we employed high-throughput sequencing to investigate the impacts of concurrent PFASs and CAHs on the indigenous microbial communities in soil and groundwater. Additionally, we assessed the relative contributions of deterministic and stochastic processes in shaping microbial community assembly across these two subsurface compartments. The results revealed that perfluorooctanoic acid was the dominant PFAS compound in subsurface, and short-chain perfluorocarboxylic acids (C &lt; 8) were prevalent in groundwater, while perfluorosulfonic acids were more likely retained in soil. CAHs were detected at concentrations up to 650.15 mg/L in groundwater, suggesting the presence of dense non-aqueous-phase liquids in subsurface. The comparative analysis on the microbial diversity and compositions showed that microbial diversity in groundwater was more influenced by the distribution of contaminants compared to that in soil. Additionally, the βNTI analysis results indicated that microbial community assembly in soil was mainly shaped by homogeneous selection, whereas stochastic processes dominated the evolution of microbial community in groundwater. Furthermore, anaerobic fermentative taxa species such as <em>Bacillus</em> and <em>Sva0485</em> dominated in soil, while aerobic pollutant-degrading taxa like <em>Oxalobacteraceae</em> and <em>Dehalogenimonas</em> were enriched in groundwater. These findings highlight the need to consider microbial communities and ecological processes when designing effective <em>in-situ</em> bioremediation strategies.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"386 ","pages":"Article 127186"},"PeriodicalIF":7.3,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145195193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}