Environmental Pollution最新文献

{"title":"Multiomics analysis revealed the effects of polystyrene nanoplastics at different environmentally relevant concentrations on intestinal homeostasis","authors":"Jian-Zheng Yang ,&nbsp;Ji-Hui Li ,&nbsp;Jia-Li Liu ,&nbsp;An-Ding Zhou ,&nbsp;Hui Wang ,&nbsp;Xiao-Li Xie ,&nbsp;Kai-Kai Zhang ,&nbsp;Qi Wang","doi":"10.1016/j.envpol.2025.126050","DOIUrl":"10.1016/j.envpol.2025.126050","url":null,"abstract":"<div><div>Nanoplastics pollution is a global issue, with the digestive tract being one of the first affected organs, requiring further research on its impact on intestinal health. This study involved orally exposing mice to polystyrene nanoplastics (PS-NPs) at doses of 0.1, 0.5, or 2.5 mg/d for 42 days. The effects on intestinal health were thoroughly assessed via microbiomics, metabolomics, transcriptomics, and molecular biology. Our study demonstrated that the administration of all three doses of PS-NPs resulted in increased colonic permeability, heightened colonic and peripheral inflammation, reduced levels of antimicrobial peptides, and shortened colonic length. These effects may be attributed to a reduction in the abundance of probiotic bacteria, such as Clostridia_UCG-014, Roseburia, and Akkermansia, alongside an increase in the abundance of the pathogenic bacterium Desulfovibrionaceae induced by PS-NPs. Furthermore, we underscored the crucial role of histidine metabolism in PS-NPs-induced colonic injury, characterized by a significant reduction of L-histidine, which is closely related to microbial ecological dysregulation. Corresponding to microbiota deterioration and metabolic dysregulation, transcriptome analysis revealed that PS-NPs may disrupt colonic immune homeostasis by activating the TLR4/MyD88/NF-κB/NLRP3 signaling pathway. In conclusion, this study provided novel insights into the mechanisms by which PS-NPs disrupt intestinal homeostasis through integrated multiomics analysis, revealing critical molecular pathway and providing a scientific basis for future risk assessment of nanoplastics exposure.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"372 ","pages":"Article 126050"},"PeriodicalIF":7.6,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143598869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect mechanism of low-molecular-weight organic acids during sulfidation of As(V)-bearing ferrihydrite","authors":"Yitong Yin ,&nbsp;Shanshan Yang ,&nbsp;Fei Liu ,&nbsp;Xue Wang ,&nbsp;Yue Chen ,&nbsp;Ximing Luo","doi":"10.1016/j.envpol.2025.126031","DOIUrl":"10.1016/j.envpol.2025.126031","url":null,"abstract":"<div><div>Sulfide induces the reductive dissolution of iron (oxyhydr) oxides, the primary host phases for arsenic (As), thereby triggering As release. We investigates the physicochemical mechanisms of three types of low molecular weight organic acids (LMWOAs) on sulfide-mediated reductive dissolution of As(V)-ferrihydrite and As release using batch experiments combined with hydro-chemical, spectroscopic, and microscopic analyses. Arsenate dominated the aqueous (97.2–100 %) and solid phases throughout the experiment. LMWOAs accelerated S(-II) consumption and As release by inhibiting FeS formation, with rates ordered as citric acid (CA) &gt; oxalic acid (OA) &gt; malic acid (MA) &gt; control (Kb). At S(-II): Fe = 0.5, maximum As release was 11.78 % (Kb) and 14.60 % (CA); at S(-II): Fe = 1, it was 27.58 % (Kb) and 30.71 % (OA). LMWOAs enhanced As release via non-reductive ligand dissolution of As(V)-ferrihydrite. Secondary mineral formation in later stages re-immobilized As, with mineral layers ≥50 nm thick. LMWOAs interacted differently with secondary minerals: CA primarily adsorbed on surfaces, while MA integrated into the matrix. LMWOAs influenced As redistribution in secondary minerals, increasing contamination risks. Thus, the complex effects of organic matter (OM) on Fe, S, and As biogeochemistry must be considered in risk assessments and remediation strategies for As-contaminated sites in sulfidic environments.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"372 ","pages":"Article 126031"},"PeriodicalIF":7.6,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143608420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Distinct responses of Caenorhabditis elegans to polyethylene microplastics and plant secondary metabolites","authors":"Yi Wang ,&nbsp;Wanxin Liu ,&nbsp;Ziwei Chen ,&nbsp;Kaixin Zheng ,&nbsp;Xianliang Yi ,&nbsp;Jiao Wang ,&nbsp;Xiaochen Chen ,&nbsp;Xianhua Liu","doi":"10.1016/j.envpol.2025.126051","DOIUrl":"10.1016/j.envpol.2025.126051","url":null,"abstract":"<div><div>Soil worms are among the most abundant and functionally diverse soil animals. However, they have been largely overlooked in studies on microplastic (MP) toxicity. MPs and plant secondary metabolites (PSMs) are ubiquitous in soil due to plant litter decomposition and heavy MP contamination, inevitably interacting and exerting combined toxicity on soil organisms. However, little research has been conducted on their joint effects. This study investigates the individual and combined toxic effects of polyethylene (PE) MPs and three PSMs (glycyrrhizic acid, tannic acid, and matrine) on the model organism <em>Caenorhabditis elegans</em>. Physiological and biochemical responses were assessed using fluorescence microscopy, image analysis, and statistical methods. After 42 h of exposure to PE MPs and/or PSMs, worm growth and development were negatively impacted. Under experimental conditions, matrine and PE MPs synergistically inhibited worm growth, exacerbated neurological damage, and induced oxidative stress. In contrast, glycyrrhizic acid and tannic acid alleviated PE MP-induced growth inhibition, mitigated oxidative stress, and demonstrated antioxidant properties that counteracted oxidative damage. This study offers new insights into the combined effects of MPs and PSMs in soil ecosystems, contributing to ecological risk assessments and pollution management strategies.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"372 ","pages":"Article 126051"},"PeriodicalIF":7.6,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143598807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Urban trace metal contamination is negatively associated with condition and wing morphology in a common waterbird","authors":"Piotr Minias, Marcin Markowski, Mirosława Słaba, Amelia Chyb, Joanna Drzewińska-Chańko, Jan Jedlikowski, Jerzy Bańbura, Radosław Włodarczyk","doi":"10.1016/j.envpol.2025.126046","DOIUrl":"https://doi.org/10.1016/j.envpol.2025.126046","url":null,"abstract":"Urban areas suffer from different forms of environmental pollution by light, noise, and chemicals. Pollution by trace metals has long been associated with industrialization and urbanization processes, increasing the risk of bioaccumulation and compromising the health, condition, and fitness of urban animals. Here, we aimed to investigate the effects of urbanization on bioaccumulation of six trace metals (Cu, Ni, Zn, Cd, Pb, and Mn) in the integumentary structures (feathers) of a non-passerine waterbird, the Eurasian coot (<em>Fulica atra</em>). For this purpose, we quantified and compared trace metal concentrations in feathers of 300 coots from four pairs of non-urban and urban populations associated with major agglomerations in Poland. We found that concentrations of three trace metals (Cu, Ni, and Zn) were significantly higher in coots from the urban landscape, compared to individuals from natural or semi-natural non-urban habitats. Elevated trace metal concentrations were negatively associated with morphology (wing length) and condition (body mass and blood haemoglobin concentration) of coots, and these associations were detected exclusively in the urban landscape. There was limited evidence of elevated trace metal pollution in the non-urban landscape (only Cd) and only weak support for a negative association of Pb concentration with physiological stress of non-urban coots. Our results suggest that trace metal contamination may be considered an important cost of urbanization processes in wildlife. We argue that mitigation of trace metal pollution in urban ecosystems should likely increase their sustainability and viability of urban animal populations.","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"183 1","pages":""},"PeriodicalIF":8.9,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143608178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Organic matter content, source, and composition varying with seasons and anthropogenic activities regulate methylmercury dynamics in the Yellow River","authors":"Xiaoquan Liu ,&nbsp;Yingjun Wang ,&nbsp;Xiaomeng Ji ,&nbsp;Qingzhe Zhang ,&nbsp;Yue Song ,&nbsp;Yanbin Li ,&nbsp;Yongguang Yin ,&nbsp;Yong Cai","doi":"10.1016/j.envpol.2025.126042","DOIUrl":"10.1016/j.envpol.2025.126042","url":null,"abstract":"<div><div>Organic matter (OM) in rivers, influenced by natural and anthropogenic events, plays a critical role in regulating methylmercury (MeHg) dynamics. This study investigated the spatial-temporal patterns of MeHg and OM in the Yellow River, through collecting water and sediment samples within the dry and wet seasons and human-induced water-sediment regulation scheme (WSRS) event. During the wet season, the river water was characterized by terrigenous OM, high unfiltered MeHg (UMeHg) concentration (206 ± 83.6 pg/L), and a low UMeHg percentage in unfiltered total Hg (UTHg) (UMeHg/UTHg = 0.37 ± 0.18 %). These findings may suggest that MeHg in the wet season was likely produced in the catchment and imported into the river. In contrast, autochthonous OM predominated during the dry season, probably enhancing <em>in situ</em> MeHg production (UMeHg/UTHg = 1.01 ± 0.50 %), although UMeHg concentration was lower (81.8 ± 25.5 pg/L) due to obviously reduced external inputs. The WSRS dramatically increased water MeHg contents (589 ± 116 pg/L) and UMeHg/UTHg ratios (0.78 ± 0.16 %) probably through direct inputs of upstream reservoirs’ MeHg and resuspension of downstream sediments. Exploring the effects of OM on sediment MeHg sources suggested that MeHg in the wet season primarily originated from watershed soil inputs, while in the dry season, it mainly resulted from <em>in situ</em> Hg methylation. However, extremely low total Hg (THg) and MeHg/THg (0.02–0.35 %) indicated that sediment MeHg production may be of minor importance in the Yellow River.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"372 ","pages":"Article 126042"},"PeriodicalIF":7.6,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143608176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tracing acid mine drainage from an accidental spill on the Estuary of Huelva (SW Spain)","authors":"Rafael Pérez-López ,&nbsp;Carlos R. Cánovas ,&nbsp;Francisco Macías ,&nbsp;M. Dolores Basallote ,&nbsp;Rémi Freydier ,&nbsp;Manuel Olías ,&nbsp;José Miguel Nieto","doi":"10.1016/j.envpol.2025.126033","DOIUrl":"10.1016/j.envpol.2025.126033","url":null,"abstract":"<div><div>The Estuary of Huelva in southwestern Spain is severely impacted by acid mine drainage (AMD), primarily due to extensive mining activities in the Iberian Pyrite Belt (IPB), and to a lesser extent by industrial sources. The AMD has led to significant contamination of the Odiel and Tinto rivers, which carry high loads of metals into the estuary. In May 2017, an accidental spill occurred at La Zarza mine, releasing approximately 270,000 m³ of acidic water contained in a pit lake. This event increased the contamination levels in the Odiel River and subsequently in the Estuary of Huelva and the Atlantic Ocean. The current focus of our investigation is to understand the geochemical behavior of contaminants during estuarine mixing and evaluate the environmental impact of the spill, from the river to the littoral. Key findings include the chronic exposure of the estuary to mining pollutants, with specific contaminants escaping retention processes and altering the metal background levels in the Gulf of Cádiz. This study highlights the need for effective control measures in historical abandoned mining districts worldwide to prevent similar environmental disasters in the future.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"372 ","pages":"Article 126033"},"PeriodicalIF":7.6,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143608422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Elevated levels of tritium in surface water collected in the immediate aftermath of the Fukushima accident","authors":"Khemruthai Kheamsiri ,&nbsp;Donovan Anderson ,&nbsp;Hirofumi Tazoe ,&nbsp;Kazusa Okada ,&nbsp;Nao Otashiro ,&nbsp;Haruka Kuwata ,&nbsp;Hideki Kakiuchi ,&nbsp;Masahiro Hosoda ,&nbsp;Tibor Kovács ,&nbsp;Shinji Tokonami ,&nbsp;Naofumi Akata","doi":"10.1016/j.envpol.2025.126040","DOIUrl":"10.1016/j.envpol.2025.126040","url":null,"abstract":"<div><div>The Fukushima Daiichi Nuclear Power Plant (FDNPP) accident in 2011, triggered by the Tohoku earthquake and tsunami, released a substantial amount of radionuclides into the environment, including approximately 2.7 PBq of ¹³⁷Cs and 200–210 TBq of tritium (³H). While extensive research has reported ¹³⁷Cs concentrations across various environmental media, data on ³H levels in water resources immediately following the accident remain limited. This study examines ³H concentrations in terrestrial surface water collected from one week to 100 days post-accident. ³H concentrations ranged from 0.3 to 267.8 Bq L⁻¹, with the highest levels exceeding typical background concentrations (0.5–2 Bq L⁻¹) by a factor of 200. The highest ³H concentration (267.8 Bq L⁻¹) was measured in snowmelt collected 100 km from the FDNPP one week after the accident, suggesting that snowfall effectively deposited atmospheric ³H. By one-month post-accident, all surface water samples showed ³H levels consistent with natural background concentrations, indicating rapid dispersion and dilution. No correlation was found between ¹³⁷Cs and ³H concentrations, likely due to their differing deposition mechanisms and environmental behaviors. An annual effective dose estimation, based on the ingestion of the most contaminated sample (snowmelt), was 3.5 × 10⁻³ Sv y⁻¹—286 times lower than the 1 mSv annual dose limit for the general public.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"372 ","pages":"Article 126040"},"PeriodicalIF":7.6,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143598815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Ecotoxicological effects of Diclofenac and Gentamicin on Mytilus galloprovincialis: What Does In Vivo Reveal That In Vitro Fails to Show?","authors":"Afonso Pereira, Marta Cunha, Alessia Cuccaro, Hugo C. Vieira, Yide He, Amadeu M.V.M. Soares, Rosa Freitas","doi":"10.1016/j.envpol.2025.126045","DOIUrl":"https://doi.org/10.1016/j.envpol.2025.126045","url":null,"abstract":"This study investigated the toxicological effects of diclofenac (DIC) and gentamicin (GEN) on the gills (G) and digestive gland (DG) of <em>Mytilus galloprovincialis</em> through <em>in vitro</em> and <em>in vivo</em> assays. Biochemical markers related to oxidative stress, metabolic capacity and neurotoxicity were evaluated at the end of each assay. For both assays, Principal coordinates analysis (PCO) highlighted distinct biochemical profiles between G and DG, mostly related to higher basal values for several biomarkers in DG. Integrated Biomarker Response (IBR) Index revealed higher scores in G for the <em>in vitro</em> assay, especially after exposure to GEN. In the <em>in vivo</em> assay the highest scores were recorded in DG, especially in the presence of DIC. The distinct responses of G and DG underscore their roles in respiration and detoxification, with G being more sensitive to acute stress and DG exhibiting greater adaptive capacity over time. Furthermore, it appears that GEN caused the greatest impact on G after the <em>in vitro</em> assay, while DIC had the most significant effect on DG following the <em>in vivo</em> experiment. <em>In vitro</em> assays demonstrated limited oxidative stress and cellular damage, while <em>in vivo</em> results highlighted substantial metabolic depression and biomarker variability under prolonged exposure. When analyzed individually, the <em>in vitro</em> assay showed a clearer distinction between the two contaminants, especially in the DG. The findings underscore the differential vulnerability and adaptive capacities of G and DG, attributed to their respective roles in respiration and detoxification. These results emphasize the complementary nature of <em>in vitro</em> and <em>in vivo</em> approaches, with the former providing mechanistic insights and the latter reflecting systemic organismal responses. This study highlights the importance of a multi-dimensional approach, combining both <em>in vitro</em> and <em>in vivo</em> methodologies, to better understand tissue-specific toxicity and the broader ecological consequences of pharmaceutical contamination.","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"14 1","pages":""},"PeriodicalIF":8.9,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143598812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Soil enzyme activities and bacterial communities respond to co-exposure of butyl benzyl phthalate and TiO2 nanomaterials: Earthworm-mediated effects","authors":"Wanjing Liu ,&nbsp;Xiaoqing Yang ,&nbsp;Zhuofan Li ,&nbsp;Yao Liu ,&nbsp;Mengyao Yao ,&nbsp;Mengyuan Pei ,&nbsp;Lanlan Zhang ,&nbsp;Cheng Zhang ,&nbsp;Lusheng Zhu ,&nbsp;Peng Gao ,&nbsp;Jun Wang","doi":"10.1016/j.envpol.2025.126049","DOIUrl":"10.1016/j.envpol.2025.126049","url":null,"abstract":"<div><div>Phthalic acid esters (PAEs) are widely used due to their advantageous properties, which enhance the durability, flexibility, and transparency of plastic products. Nanomaterials are also commonly used in plastic additives and agricultural fertilizers. However, both are easy to fall off, diffuse, and release into the environment during production, use, and disposal. The adsorption and transportation of PAEs by nanomaterials may jointly affect soil health. However, less attention is paid to the soil microorganisms caused by co-exposure between PAEs and nanomaterials, especially mediated by earthworms. The present study investigated the effects of BBP (1 mg kg⁻¹) and nTiO₂ (1 mg kg⁻¹), alone and in combination, on soil enzyme activities, microbial composition, and bacterial community diversity, with and without mediation by the earthworm <em>Metaphire guillelmi</em>. Results showed that co-exposure to BBP and nTiO₂ activated enzyme activities in earthworm-mediated soil. Both contaminants, individually and combined, altered the composition, distribution, diversity, and complexity of the soil bacterial community mediated by earthworms. Bacteroidetes, Proteobacteria, and Actinobacteria were the dominant phyla. However, the complexity of soil bacterial community networks decreased. The findings highlight the importance of considering co-exposure and soil fauna mediation when evaluating the ecological impacts of emerging contaminants and fill the lack of ecotoxicity data on the co-exposure of PAEs and nanomaterials, thus promoting the design and synthesis of safer and more efficient nanomaterials.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"372 ","pages":"Article 126049"},"PeriodicalIF":7.6,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143598810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between short-term exposure to PM2.5 and its components and mumps incidences in Lanzhou, China","authors":"Zixuan Zou, Zhenjuan Li, Donghua Li, Tingrong Wang, Rui Li, Tianshan Shi, Xiaowei Ren","doi":"10.1016/j.envpol.2025.126041","DOIUrl":"https://doi.org/10.1016/j.envpol.2025.126041","url":null,"abstract":"To date, a limited number of studies have assessed the impact of individual and combined PM_2.5 components on mumps incidence. Between 2013 and 2019, we collected data on 6,270 mumps cases in Lanzhou, along with corresponding PM_2.5 and its components, to analyze their temporal and spatial distributions. A generalized additive mixture model was constructed to examine the association between PM_2.5 components and mumps incidence. Additionally, Bayesian kernel machine regression was used to evaluate the combined and interactive effects of co-exposure to PM_2.5 components on mumps incidence and to identify key contributing components. A significant linear correlation was found between PM_2.5 and mumps incidence at lag 1 month, with a relative risk (RR) of 1.85 (95% CI: 1.14, 3.02) for each unit increase in PM_2.5 (ln (PM_2.5) = 1 μg/m³). Organic matter (OM) at lag 0 and 1 month, as well as black carbon (BC) at lag 1 month, were significantly positively correlated with mumps incidence. Furthermore, the joint exposure-effect curve for PM_2.5 components and mumps incidence displayed an approximate V-shape. The effects of PM_2.5 and its components on mumps incidence were more pronounced during the warm season. These findings suggest a significant association between short-term exposure to PM_2.5 and its components and mumps incidence in Lanzhou, with potential variations in effect depending on the specific components of PM_2.5.","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"195 1","pages":""},"PeriodicalIF":8.9,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143598809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}