Environmental Pollution最新文献

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Spatial Variation of Resuspended Particulate Matter in Urban Environments and Real-World Assessment of Street Sweeping
IF 7.6 2区 环境科学与生态学
Environmental Pollution Pub Date : 2025-03-28 DOI: 10.1016/j.envpol.2025.126165
Cheol-Heon Jeong, Cuilian Fang, Greg Evans
{"title":"Spatial Variation of Resuspended Particulate Matter in Urban Environments and Real-World Assessment of Street Sweeping","authors":"Cheol-Heon Jeong,&nbsp;Cuilian Fang,&nbsp;Greg Evans","doi":"10.1016/j.envpol.2025.126165","DOIUrl":"10.1016/j.envpol.2025.126165","url":null,"abstract":"<div><div>Non-tailpipe emissions have gained growing attention as an emerging source of traffic-related air pollution, especially as tailpipe emissions decline. This study conducted extensive mobile measurements in a high-density urban area over two years to investigate the spatial variability of resuspended road dust and evaluate the real-world effectiveness of street sweeping. Resuspended particulate matter (PM), specifically PM<sub>2.5</sub> and PM<sub>10</sub>, was measured alongside pollutants from tailpipe and non-tailpipe sources. The mobile sampling revealed substantial spatial variability in resuspended PM with notably higher concentrations on local streets compared to major roads. This spatial pattern contrasted with tailpipe-related black carbon and ultrafine particles, which were elevated near highways, commercial, and industrial zones. Nearby construction and renovation activities were major contributors to resuspended PM on local streets. As a result, school neighborhoods in residential areas and open spaces may experience acute exposure to road dust PM.</div><div>Street sweepers equipped with regenerative air systems were generally ineffective in reducing resuspended PM under real-world conditions. This trend was consistent across different types of regenerative sweepers and operational modes, except for one sweeper equipped with an advanced filtration system showing some reduction in resuspended PM. Operational factors, including sweeper speed and water spraying, substantially influenced PM resuspension. While water spraying reduced on-road PM during sweeping, excessive use resulted in unintended increases in both resuspended and on-road PM concentrations afterward. While street sweeping helps to manage debris on road surfaces, these findings underscore the need to optimize sweeping practices and develop strategies to improve near-road air quality.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"373 ","pages":"Article 126165"},"PeriodicalIF":7.6,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143734196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tracing emerging contaminants from the Baltic Sea and North Sea in fjord waters in southern Norway with rare earth elements as far-field tracers
IF 8.9 2区 环境科学与生态学
Environmental Pollution Pub Date : 2025-03-27 DOI: 10.1016/j.envpol.2025.126124
Anna-Lena Zocher, Tomasz Maciej Ciesielski, Stefania Piarulli, Julia Farkas, Michael Bau
{"title":"Tracing emerging contaminants from the Baltic Sea and North Sea in fjord waters in southern Norway with rare earth elements as far-field tracers","authors":"Anna-Lena Zocher, Tomasz Maciej Ciesielski, Stefania Piarulli, Julia Farkas, Michael Bau","doi":"10.1016/j.envpol.2025.126124","DOIUrl":"https://doi.org/10.1016/j.envpol.2025.126124","url":null,"abstract":"Knowledge of geogenic and anthropogenic rare earth elements and yttrium (REY) in fjords in Norway and elsewhere is still limited despite the importance of fjords for biodiversity and economy and the known ecotoxicity of the REY. We provide complete sets of REY data for fjord waters and a river in southern Norway and for several stations along the coasts of Denmark and Sweden, which characterise Baltic Sea outflow water.Shallow fjord waters show high REY concentrations and shale-normalised (<sub>SN</sub>) patterns that resemble those of the river water input. Deeper waters show lower concentrations, seawater-like REY<sub>SN</sub> patterns, and the Pr<sub>SN</sub>/Tb<sub>SN</sub> ratios (≥ 0.5) typical of fjord waters. Some of the samples show elevated Gd/Tb ratios and distinct positive Gd anomalies, revealing the presence of anthropogenic Gd originating from constrast agents used in magnetic resonance imaging (MRI).We emphasise that <em>all</em> water samples from the Baltic Sea outflow taken over a twelve months period show large positive Gd anomalies, suggesting permanent input of anthropogenic Gd from the Baltic Sea into the Skagerrak. Combined with literature data, our results suggest that the anthropogenic Gd in the fjords of southern Norway is not derived from local sources. It rather originates from the Baltic Sea and southern North Sea and is transported northward by currents along the coasts of Sweden, Denmark and Germany. If application of Gd-based contrast agents in MRI continues to increase, this signal will get stronger in the future and be transported even further north.Overall, our data for geogenic REY and anthropogenic Gd in fjord and bay waters from southern Norway and in the Baltic Sea outflow show that local hydrography exerts an important control on the concentration and distribution of trace elements which may be (micro)nutrients and/or (micro)pollutants in fjords and needs to be considered in environmental impact studies.","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"36 1","pages":""},"PeriodicalIF":8.9,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143723546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors influencing the vertical distribution and transport of plastics in riverine environments: Theoretical background and implications for improved field study design
IF 7.6 2区 环境科学与生态学
Environmental Pollution Pub Date : 2025-03-27 DOI: 10.1016/j.envpol.2025.126151
Jenna Brooks, Julia Hopkins
{"title":"Factors influencing the vertical distribution and transport of plastics in riverine environments: Theoretical background and implications for improved field study design","authors":"Jenna Brooks,&nbsp;Julia Hopkins","doi":"10.1016/j.envpol.2025.126151","DOIUrl":"10.1016/j.envpol.2025.126151","url":null,"abstract":"<div><div>Rivers have been widely recognized as important conduits and accumulation sites for plastics. Accurately describing plastic fate and transport in these systems is essential for the development of numerical models, estimating loads to oceans, and implementing effective management strategies. However, plastic transport mechanisms within fluvial environments are not well understood, and field studies often do not provide sufficient information to test analytical models of transport. Sediment transport has dynamical similarities to plastics transport in water bodies, enough to warrant further investigation into how principles from sediment transport can be used to guide the study of plastics. In this review, we summarize fundamentals from sediment transport research and their application to plastics, then use these to make suggestions of clarifying research questions and riverine field study design with the goal of generating more insightful data that can be used to understand and predict plastic fate and transport. We focus specifically on factors influencing plastic vertical distribution and movement in the water column, as variations in this direction have historically been overlooked or oversimplified in rivers.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"373 ","pages":"Article 126151"},"PeriodicalIF":7.6,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143723548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Uncovering the partitioning, transport flux and socioeconomic factors of organophosphate esters in an urban estuary of eastern China
IF 7.6 2区 环境科学与生态学
Environmental Pollution Pub Date : 2025-03-27 DOI: 10.1016/j.envpol.2025.126132
Ya Yang , Lai Wei , Rui Wang , Guohua Zhao , Shouye Yang , Haifeng Cheng , Hualin Wu , Qinghui Huang
{"title":"Uncovering the partitioning, transport flux and socioeconomic factors of organophosphate esters in an urban estuary of eastern China","authors":"Ya Yang ,&nbsp;Lai Wei ,&nbsp;Rui Wang ,&nbsp;Guohua Zhao ,&nbsp;Shouye Yang ,&nbsp;Haifeng Cheng ,&nbsp;Hualin Wu ,&nbsp;Qinghui Huang","doi":"10.1016/j.envpol.2025.126132","DOIUrl":"10.1016/j.envpol.2025.126132","url":null,"abstract":"<div><div>The Yangtze River Estuary is considered as a critical transition zone for terrestrial organophosphate esters (OPEs) transported to the open sea, yet their environmental behavior and influencing drivers remain inadequately investigated. Here, we examine the occurrence of eleven OPEs across water, suspended particulate matter (SPM), and sediment, which reveals moderate pollution levels compared to other Chinese estuaries. The OPE partitioning processes are dependent on compound-specific partition coefficients (log <em>K</em><sub>d</sub>), hydraulic factors, and terrestrial input. Compounds with lower log <em>K</em><sub>ow</sub> remain mostly dissolved or particulate-bound, whereas higher log <em>K</em><sub>ow</sub> OPEs tend to be deposited in sediment. Riverine input and output emerge as the dominant transport pathways for OPEs within the YRE, with an annual input flux of 677 tons. Modeling reveals that tris(1-chloro-2-propyl) phosphate (TCIPP), tris(2-chloroethyl) phosphate (TCEP), and triethyl phosphate (TEP) face significant resuspension risks, indicating their increased transport into the open sea, while tris(2-ethylhexyl) phosphate (TEHP) presents a remarkable sedimentary risk due to its high hydrophobicity. The results suggest that the YRE functions as a source for resuspension-prone compounds and a sink for sediment-bound OPEs, demonstrating their distinct environmental fates. Additionally, aggravating pollution of OPEs has been observed in the Pearl River, Yellow River, and Yangtze River Estuaries with sustained wastewater discharge and rapid urbanization. This study provides an overview of the partitioning processes, transport mechanisms, and anthropogenic threats, thus underlining the need for effective pollution mitigation to protect estuarine ecosystems and promote sustainable water management.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"373 ","pages":"Article 126132"},"PeriodicalIF":7.6,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143723929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterization and risk-quantification of antibiotic resistome in grain-based and non-grain cropping soils
IF 7.6 2区 环境科学与生态学
Environmental Pollution Pub Date : 2025-03-27 DOI: 10.1016/j.envpol.2025.126147
Jingpeng Li , Lin Zhu , Xiaodi Li , Xuezhu Han , Jiaming Yi , Ying Wu , Meizhen Wang
{"title":"Characterization and risk-quantification of antibiotic resistome in grain-based and non-grain cropping soils","authors":"Jingpeng Li ,&nbsp;Lin Zhu ,&nbsp;Xiaodi Li ,&nbsp;Xuezhu Han ,&nbsp;Jiaming Yi ,&nbsp;Ying Wu ,&nbsp;Meizhen Wang","doi":"10.1016/j.envpol.2025.126147","DOIUrl":"10.1016/j.envpol.2025.126147","url":null,"abstract":"<div><div>Microbial contamination in soils, encompassing human bacterial pathogens (HBPs), antibiotic resistance genes (ARGs), and virulence factor genes (VFGs), poses a significant threat to human health via the food chain. Currently, there is a lack of comprehensive assessments of microbial contamination and associated health risks of ARGs in agricultural soils. In this study, metagenomic sequencing was used to evaluate microbial contamination in grain-based cropping soils (rice cultivation) and non-grain cropping soils (vegetable cultivation and aquaculture). The results showed that the diversity and abundance of HBPs and VFGs were significantly higher in non-grain soils. Further resistome analysis revealed higher abundances of high-risk (from 0.014 to 0.018–0.023) and “last-resort” ARGs (from 0.007 to 0.034–0.046) in non-grain soils. Besides ARGs abundance, health risk quantification revealed that non-grain soils exhibited 1.49–2.14-fold greater ARG-related risks than grain-based soils. Additionally, stronger network associations were found between HBPs, ARGs, and mobile genetic elements (MGEs) in non-grain soils. This study indicated that the non-grain cropping pattern of soils elevated the risk of microbial contamination and ARGs health risk, which provided an important basis for accurately quantifying the risk of microbial contamination in different agricultural soils.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"373 ","pages":"Article 126147"},"PeriodicalIF":7.6,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143713326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Distribution characteristics of volatile organic compounds and its multidimensional impact on ozone formation in arid regions based on machine learning algorithms
IF 7.6 2区 环境科学与生态学
Environmental Pollution Pub Date : 2025-03-27 DOI: 10.1016/j.envpol.2025.126159
Guangyao Shi , Huihui Du , Lingtong Du , Xilu Ni , Yang Hu , Danbo Pang , Liangjin Yao
{"title":"Distribution characteristics of volatile organic compounds and its multidimensional impact on ozone formation in arid regions based on machine learning algorithms","authors":"Guangyao Shi ,&nbsp;Huihui Du ,&nbsp;Lingtong Du ,&nbsp;Xilu Ni ,&nbsp;Yang Hu ,&nbsp;Danbo Pang ,&nbsp;Liangjin Yao","doi":"10.1016/j.envpol.2025.126159","DOIUrl":"10.1016/j.envpol.2025.126159","url":null,"abstract":"<div><div>Volatile Organic Compounds (VOCs) are key components of atmospheric pollution and play a critical role in ozone (O<sub>3</sub>) formation. Understanding their distribution and pollution sources is essential to grasping the multifaceted impact of VOCs on O<sub>3</sub> production. This study, conducted at the Yinchuan Urban Ecosystem Research Station, carried out simultaneous field observations to collect data on VOCs, meteorological factors, and O<sub>3</sub>. Machine learning algorithms were employed to analyze the sources of VOCs pollution and evaluate their impact on O<sub>3</sub> formation. Results show that the monthly average volume fraction of total VOCs was 29.28 × 10<sup>−9</sup>, with alkanes dominating, accounting for 51.1 % of total VOCs during summer at high altitudes. Ethane (3.55 × 10<sup>−9</sup>), n-hexane (3.36 × 10<sup>−9</sup>), and propane (2.85 × 10<sup>−9</sup>) were identified as key components. Artificial source contributed 78.6 % of VOCs emissions in summer, with hydrocarbon volatile emission source (31.6 %) and vehicle emission source (30.1 %) being the major sources, while natural emissions accounted for only 21.4 %. VOCs exhibited a notable negative impact on O<sub>3</sub> levels, reflected by a total effect value of −0.29. Among the VOCs components, aromatics, halocarbons, and alkanes were identified as the primary contributors to O<sub>3</sub> dynamics, with respective effect values of 0.84, 0.75, and 0.71, and their contribution rates were quantified as 21.8 %, 19.4 %, and 18.4 %, respectively. Among meteorological factors, temperature was a key determinant of O<sub>3</sub> levels, with a significant positive effect (effect value of 0.58). Temperature, wind speed, and relative humidity primarily influenced O<sub>3</sub> through direct effects, while photosynthetically active radiation indirectly influenced O<sub>3</sub> by affecting VOCs. The findings of this study link pollution sources, meteorological factors, and air quality management. Through systematic multidimensional analysis, it offers deeper insights into the complex relationships between meteorological factors, VOCs, and O<sub>3</sub> in high-altitude areas. These insights provide a scientific basis for formulating precise, region-specific, and component-targeted air pollution control measures.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"373 ","pages":"Article 126159"},"PeriodicalIF":7.6,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143723977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unraveling the impact of micro- and nano-sized polymethyl methacrylate on gut microbiota and liver lipid metabolism: Insights from oral exposure studies
IF 7.6 2区 环境科学与生态学
Environmental Pollution Pub Date : 2025-03-27 DOI: 10.1016/j.envpol.2025.126157
Peng Chen Zheng , Xin Qiang Pan , Yi Jiong Zhou , Keng Po Lai , Rong Li , Xiao Xi Zhang
{"title":"Unraveling the impact of micro- and nano-sized polymethyl methacrylate on gut microbiota and liver lipid metabolism: Insights from oral exposure studies","authors":"Peng Chen Zheng ,&nbsp;Xin Qiang Pan ,&nbsp;Yi Jiong Zhou ,&nbsp;Keng Po Lai ,&nbsp;Rong Li ,&nbsp;Xiao Xi Zhang","doi":"10.1016/j.envpol.2025.126157","DOIUrl":"10.1016/j.envpol.2025.126157","url":null,"abstract":"<div><div>Microplastics, particularly polymethyl methacrylate (PMMA), have emerged as significant environmental pollutants, with growing concerns about their impact on various biological processes. However, the effects of chronic PMMA exposure on hepatic lipid metabolism remain insufficiently studied. This research aimed to examine the consequences of chronic exposure to PMMA particles of different sizes (100 nm and 2 μm) on hepatic lipid metabolism in mice. Female C57BL/6J mice were administered PMMA particles in drinking water over an 8-week period, and the effects on intestinal and liver morphology and function were evaluated. Histopathological analyses, gut microbiota profiling, and serum and liver assays were conducted to assess oxidative stress, lipid metabolism-related biomarkers, and liver metabolomics. The results revealed that PMMA particles accumulated in both the liver and colon, causing liver injury characterized by elevated ALT and AST levels. The exposure also induced oxidative stress by inhibiting the NRF2/HO-1 signaling pathway. Furthermore, PMMA exposure resulted in significant alterations to the gut microbiota and hepatic metabolism. These changes were linked to increased microbial diversity, which impacted cholesterol metabolism through the gut-liver axis. Additionally, the activation of the PI3K/AKT/PPARγ signaling pathway disrupted hepatic lipid metabolism, leading to increased cholesterol synthesis and hepatic lipid accumulation. This study underscores the potential of PMMA to disrupt both hepatic lipid metabolism and gut microbiota composition, suggesting a novel mechanism by which PMMA exposure could contribute to metabolic disorders and liver disease.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"373 ","pages":"Article 126157"},"PeriodicalIF":7.6,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143723544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Temporal trends of persistent organic pollutants (POPs) and perfluoroalkyl substances (PFAS) in Adèlie penguin (Pygoscelis adeliae) eggs from the Ross Sea (Antarctica), including their relationship with climate parameters
IF 7.6 2区 环境科学与生态学
Environmental Pollution Pub Date : 2025-03-27 DOI: 10.1016/j.envpol.2025.126130
Nicolas Pala , Katrin Vorkamp , Rossana Bossi , Anders Bignert , Giacomo Traversa , Davide Fugazza , Stefania Ancora , Nicoletta Ademollo , Davide Baroni , Simonetta Corsolini
{"title":"Temporal trends of persistent organic pollutants (POPs) and perfluoroalkyl substances (PFAS) in Adèlie penguin (Pygoscelis adeliae) eggs from the Ross Sea (Antarctica), including their relationship with climate parameters","authors":"Nicolas Pala ,&nbsp;Katrin Vorkamp ,&nbsp;Rossana Bossi ,&nbsp;Anders Bignert ,&nbsp;Giacomo Traversa ,&nbsp;Davide Fugazza ,&nbsp;Stefania Ancora ,&nbsp;Nicoletta Ademollo ,&nbsp;Davide Baroni ,&nbsp;Simonetta Corsolini","doi":"10.1016/j.envpol.2025.126130","DOIUrl":"10.1016/j.envpol.2025.126130","url":null,"abstract":"<div><div>Temporal trends of contaminants represent an important tool to evaluate the effectiveness of chemical restriction measures. In this work, 50 eggs of Adèlie penguin (<em>Pygoscelis adeliae</em>) collected along the Ross Sea coasts from 1997 to 2021 were analysed for polychlorinated biphenyls (PCBs), polybrominated diphenyl ethers (PBDEs), hexachlorobenzene (HCB), <em>p,p’</em>-dichlorodiphenyldichloroethylene (<em>p,p’</em>-DDE), perfluoroalkyl substances (PFAS). Some PCB congeners showed a significantly decreasing trend, whereas HCB and <em>p,p’</em>-DDE indicated decreasing but not significant trends, potentially related to the unintentional production of HCB and ongoing use of DDT, even if a contribution from climate-driven remobilisation mechanisms may also play a role. PBDE-47 also indicated a decreasing but not significant trend, which might be explained by the more recent global restriction. PFAS trends agreed with what has been previously observed in the Arctic, i.e. significantly decreasing perfluorooctane sulfonate (PFOS) according to its global ban and increasing long-chain perfluorinated carboxylic acids (PFCAs). Correlations with selected climate parameters showed an association between PBDE-47 and sampling year precipitations. To our knowledge, this work represents the longest time trend study of pollutants in penguins from the Ross Sea and the first one reporting PFAS. It highlights the importance of global regulations for the contaminant developments in polar ecosystems.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"373 ","pages":"Article 126130"},"PeriodicalIF":7.6,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143723592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The exposure to nandrolone changed the expression of genes associated with sexual differentiation and disrupted the levels of hormones in the hypothalamic-pituitary-gonadal (HPG) axis, ultimately inducing male differentiation in zebrafish (Danio rerio)
IF 7.6 2区 环境科学与生态学
Environmental Pollution Pub Date : 2025-03-27 DOI: 10.1016/j.envpol.2025.126156
Yufei Xie , Qiuyu Liu , Wenting Lin , Yuan Ren , Lingtian Xie
{"title":"The exposure to nandrolone changed the expression of genes associated with sexual differentiation and disrupted the levels of hormones in the hypothalamic-pituitary-gonadal (HPG) axis, ultimately inducing male differentiation in zebrafish (Danio rerio)","authors":"Yufei Xie ,&nbsp;Qiuyu Liu ,&nbsp;Wenting Lin ,&nbsp;Yuan Ren ,&nbsp;Lingtian Xie","doi":"10.1016/j.envpol.2025.126156","DOIUrl":"10.1016/j.envpol.2025.126156","url":null,"abstract":"<div><div>Various anabolic androgenic steroids (AAS) are frequently detected in aquatic environments, yet the potential ecotoxicological impacts of their increased load have not received adequate attention. This study investigates the effects of exposure to the androgen nandrolone on sex differentiation, gonadal development, and the expression of hormones, enzymes, and proteins related to the hypothalamic-pituitary-gonadal (HPG) axis in zebrafish. The results indicate that exposure to nandrolone at 60 days post-fertilization promotes the maturation of spermatogonia, inhibits the development of oocytes, and induces their apoptosis. Additionally, there were dose-dependent changes in male differentiation and hormone levels within the HPG axis: in the high-dose group (5 μg/L), males constituted 73 % of the population, and levels of E2 hormones in gonadal tissues decreased by 33 %, while T hormone levels increased by 55 %. Furthermore, the expression of genes essential for ovarian differentiation were downregulated, whereas the expression of testicular differentiation-related genes were upregulated. The molecular docking results show that the drug can form hydrogen bonds with key proteins, which have high affinity, and are more likely to cause conformational changes in the proteins, thereby altering their activity. KEGG analysis suggests that the MAPK signaling pathway is likely the target pathway through which nandrolone exposure induces reproductive toxicity.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"373 ","pages":"Article 126156"},"PeriodicalIF":7.6,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143723545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chlorinated paraffins exposure in particulate matter increase the risk of attention-deficit/hyperactivity disorder symptoms in children and adolescents
IF 7.6 2区 环境科学与生态学
Environmental Pollution Pub Date : 2025-03-27 DOI: 10.1016/j.envpol.2025.126120
Wan-Ting He , Jing-Wen Huang , Yun-Ting Zhang , Edwin Trevathan , Zhengmin Qian (Min) , Ri'enna Boyd , Michael Elliott , Li-Zi Lin , Zhao-Huan Gui , Ru-Qing Liu , Li-Wen Hu , Guang-Hui Dong
{"title":"Chlorinated paraffins exposure in particulate matter increase the risk of attention-deficit/hyperactivity disorder symptoms in children and adolescents","authors":"Wan-Ting He ,&nbsp;Jing-Wen Huang ,&nbsp;Yun-Ting Zhang ,&nbsp;Edwin Trevathan ,&nbsp;Zhengmin Qian (Min) ,&nbsp;Ri'enna Boyd ,&nbsp;Michael Elliott ,&nbsp;Li-Zi Lin ,&nbsp;Zhao-Huan Gui ,&nbsp;Ru-Qing Liu ,&nbsp;Li-Wen Hu ,&nbsp;Guang-Hui Dong","doi":"10.1016/j.envpol.2025.126120","DOIUrl":"10.1016/j.envpol.2025.126120","url":null,"abstract":"<div><div>Chlorinated paraffins (CPs), widely distributed environmental and industrial pollutants, have been linked to impaired neurodevelopment. However, evidence for this potential association between CP exposure and the risk of Attention-Deficit Hyperactivity Disorder (ADHD) and subtypes is lacking. To investigate this possible association between chlorinated paraffins exposure and the risk of ADHD and its subtypes in children and adolescents, a large cross-sectional study was conducted in the Pearl River Delta (PRD) in China involving 122,965 completed questionnaires. Particle matters &lt;2.5 μm (PM<sub>2.5</sub>) samples and PM<sub>2.5</sub>-bound short-chain CPs (SCCPs), medium-chain CPs (MCCPs), and long-chain CPs (LCCPs) in the PRD were collected and detected. Generalized linear mixed models (GLMM) and restricted cubic spline (RCS) models were used to estimate the association between CP exposure and ADHD symptoms and subtypes, as well as dose-response relationships. Quantile g-computation models (qgcomp) were performed to explore further the joint effects of a mixture of CPs exposure on ADHD symptoms and subtypes. A total of 7139 participants (5.8 %) were diagnosed with ADHD. GLMM analysis found that an interquartile range (IQR) increase in ∑CP concentrations was associated with the risk of ADHD after adjusting the covariates, and the odds ratio and corresponding 95 % confidence interval was 1.57 (1.54, 1.61). The RCS model showed a monotone-increased dose-response association between CP exposure and ADHD symptoms. Qgcomp model analysis indicated that SCCPs and MCCPs were the major contributors to the risk of ADHD symptoms. Furthermore, girls exhibited a significantly higher risk of developing ADHD and it subtypes compared to boys following exposure to CPs. Above all, our findings suggest that PM<sub>2.5</sub>-bound CP exposure may increase the risk of ADHD symptoms and subtypes, and provide novel evidence for atmospheric environmental risk factors for ADHD.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"373 ","pages":"Article 126120"},"PeriodicalIF":7.6,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143723547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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