Environmental Pollution最新文献

{"title":"Mycotoxin Alternariol exposure promotes endoplasmic reticulum stress-induced hepatotoxicity to exacerbate chronic liver injury","authors":"Song Yu ,&nbsp;Xia Shen ,&nbsp;Yanqiu Huang ,&nbsp;Lianpeng Zou ,&nbsp;Chenghao Zhang ,&nbsp;Jianwen Cheng ,&nbsp;Yang Yang","doi":"10.1016/j.envpol.2025.127217","DOIUrl":"10.1016/j.envpol.2025.127217","url":null,"abstract":"<div><div>As a mycotoxin ubiquitously detected in global food supplies, Alternariol (AOH) has garnered significant attention due to its documented health risks. However, hepatotoxic effect of chronic exposure to AOH at environmental levels remains poorly characterized. Herein, we aim to investigate the long-term effects of dietary AOH exposure on murine liver and key signaling event through integrated <em>in vivo</em> and <em>in vitro</em> models. AOH exposure significantly induced dose-dependent hepatopathy characterized by liver injury, inflammatory cell infiltration, and liver fibrosis. RNA-sequencing analyses further indicated that the pivotal molecular mechanism linking the hepatotoxic effect of AOH were endoplasmic reticulum (ER) stress-mediated apoptosis via PERK/ATF4/CHOP signaling cascade. <em>In vitro</em> models confirmed AOH promoted the PERK/ATF4/CHOP signaling activation and subsequent apoptosis in primary murine hepatocytes and human hepatocyte cell line THLE-2. Pharmacological intervention studies demonstrated that both TUDCA (ER stress inhibitor) and GSK2606414 (PERK inhibitor) effectively mitigated AOH-induced cytotoxicity in hepatocytes. Notably, TUDCA administration demonstrated therapeutic efficacy in mitigating AOH-induced hepatic pathology in mice. Thus, we delineate ER stress as central mechanism driving AOH-induced hepatotoxicity and validate PERK cascade inhibition as viable protective strategy. These findings fundamentally refine risk assessment framework for mycotoxin exposure while proposing novel molecular targets for therapeutic intervention against environmental hepatotoxicants.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"386 ","pages":"Article 127217"},"PeriodicalIF":7.3,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145235230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chroococcus minor cathode and polyphenolic mediated anode for enhancing bioenergy and bioremediation in a novel microbial desalination cell","authors":"Sandhya Prakash,&nbsp;Samsudeen Naina Mohamed,&nbsp;Kalaichelvi Ponnusamy","doi":"10.1016/j.envpol.2025.127218","DOIUrl":"10.1016/j.envpol.2025.127218","url":null,"abstract":"<div><div>The algal biocathode offers a sustainable, cost-effective alternative to chemical cathodes in microbial desalination cells (MDCs). This study evaluated <em>Chroococcus minor</em> as a biocathode with <em>Shewanella putrefaciens</em> MTCC 8104 (Sh-MDC) and mixed culture (Mx-MDC) exoelectrogens in a novel concentrically arranged MDC using sago effluent as anolyte and 30 g/L NaCl in the central desalination chamber. The influence of microalgal growth on MDC performance was monitored over 30 days. Sh-MDC achieved a peak power density of 31.7 ± 0.6 mW/m², while Mx-MDC reached 20.8 ± 0.4 mW/m² between days 10–15, comparable to abiotic MDCs. Mx-MDC recorded the highest COD removal (92.9 ± 2 %) between days 25–30, along with significant removal of metals (Al, Ag, Pb) from sago effluent. Microbial community analysis of Mx-MDC revealed a high abundance of electrogenic populations. The system's application for brackish water treatment in the desalination chamber was assessed. To improve performance, plant-derived mediators, <em>Chrysopogon zizanioides</em> (vetiver) and <em>Allium cepa</em> (onion) peel extracts were added to the anode chamber. The <em>C. zizanioides</em>-mediated Mx-MDC exhibited a 1.98-fold increase in power density compared to non-mediated systems. COD removal and desalination efficiencies improved to 94.3 ± 1.9 % and 21.5 ± 0.43 %, respectively. Thus, <em>C. zizanioides</em> extract is a sustainable mediator enhancing the performance of Mx-MDC over Sh-MDC. Optimizing electrogenic populations and adapting <em>C</em><em>hroococcus minor</em> to brackish conditions can further improve MDC efficiency, while the harvested algal biomass offers potential reuse, supporting a circular economy.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"386 ","pages":"Article 127218"},"PeriodicalIF":7.3,"publicationDate":"2025-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145226710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantifying anthropogenic microparticle contamination in cave sediments: spatial heterogeneity matters","authors":"Manuela Piccardo ,&nbsp;Raffaele Bruschi ,&nbsp;Tecla Bentivoglio ,&nbsp;Serena Anselmi ,&nbsp;Monia Renzi ,&nbsp;Lucia Gardossi ,&nbsp;Stanislao Bevilacqua","doi":"10.1016/j.envpol.2025.127208","DOIUrl":"10.1016/j.envpol.2025.127208","url":null,"abstract":"<div><div>Anthropogenic microparticle pollution is a pervasive phenomenon affecting even remote environments, such as natural caves. Despite potential impacts on these fragile and valuable underground ecosystems, data on microparticle concentration in natural caves still remain sparse and often based on limited sampling and insufficient spatial replication. In this study, a hierarchical sampling design including large (between caves, 1000 s m), medium (subareas within caves, 10 s m), local (stations within subareas, 100 s cm) and small (among replicates, 10 s cm) scale, was implemented to identify patterns of spatial variation in microparticle contamination of surface sediments from two caves in the Classical Karst (NE Italy). Suspected anthropogenic microparticles were detected in all samples, with an average concentration of 90.9 items kg⁻¹ dry weight, predominantly transparent particles (&gt;34.9 %), often fibers &lt;1 mm (49.9 − 58.1 %). Most of the items (94.5 %) were microplastics made of PP (45 %), PET (35 %), and PE (20 %), whereas the remaining microparticles consisted of non-plastic items, including unknown cellulose (5 %) and anthropogenic cellulose (0.5 %). The total number of microparticles, their type, and relative abundance significantly varied at the scale of subareas, while no significant variations were detected at the scale of stations and between caves. In all cases, subareas and replicates primarily contributed to the total variability (11 − 20 % and ≥80 %, respectively), highlighting small- and medium-scale heterogeneity as the most relevant sources of spatial variations of microparticle contamination. As a number of factors, from varying contamination sources to the geomorphological complexity of caves, may affect dispersal and accumulation of microparticles in environmental matrices, our findings stress the need for more structured sampling designs to quantify the intrinsic spatial variability of microparticles in order to obtain reliable estimates of contamination in cave environments.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"386 ","pages":"Article 127208"},"PeriodicalIF":7.3,"publicationDate":"2025-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145216200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative hepatotoxicity of HFPO-TA and PFOA in Opsariichthys bidens: Greater liver injury induced by the PFOA alternative","authors":"Zhenlan Xu ,&nbsp;Zhengzheng Liu ,&nbsp;Tao Tang ,&nbsp;Dou Wang ,&nbsp;Lu Lv ,&nbsp;Jinsong Liu ,&nbsp;Xinquan Wang ,&nbsp;Yanhua Wang","doi":"10.1016/j.envpol.2025.127216","DOIUrl":"10.1016/j.envpol.2025.127216","url":null,"abstract":"<div><div>Hexafluoropropylene oxide trimer acid (HFPO-TA) has been introduced as a potential alternative to the environmentally persistent perfluorooctanoic acid (PFOA). Despite its increasing application, there remains a substantial knowledge gap regarding its toxicological profile, especially in freshwater species such as the hook snout carp (<em>Opsariichthys bidens</em> Günther). To address this concern, we systematically evaluated and compared the hepatic toxicity of HFPO-TA and PFOA in <em>O. bidens</em> under uniform exposure durations for 60 days. HFPO-TA demonstrated a significantly greater capacity to induce liver injury, evidenced by pronounced oxidative stress, elevated rates of programmed cell death, and disruption of immune, hormonal, and metabolic functions, even at exposure levels approximating those detected in natural aquatic systems. Enzymatic and immunological assays showed that both HFPO-TA and PFOA suppressed the contents of carboxylesterase (CarE) (reduced by 11–65 %) and interleukin-1β (IL-1β) (reduced by 18–52 %). Moreover, the integrated biomarker response (IBR) index highlighted <em>gst</em> expression and polyphenol oxidase (PPO) activity as promising early biomarkers for detecting exposure to PFOA and HFPO-TA, respectively. Besides, the higher IBR value of HFPO-TA (with an average of 3.37) compared to that of PFOA (with an average of 2.84) suggested that this alternative polyfluoroalkyl substance (PFAS) exerted a stronger overall toxic effect on <em>O. bidens</em> than its corresponding legacy compound. Taken together, these findings implied that HFPO-TA might pose even higher toxic effects than its predecessor, challenging the assumption that newer PFAS substitutes are inherently safer. This study emphasized the necessity of critically re-evaluating the environmental safety of emerging PFAS alternatives before their widespread adoption.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"386 ","pages":"Article 127216"},"PeriodicalIF":7.3,"publicationDate":"2025-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145216198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reclaimed water irrigation in hydroponics: Dose–dependent uptake of PMT substances and implications for lettuce and human health","authors":"Alicia Cano-López ,&nbsp;Dana Orlando-Véliz ,&nbsp;Mònica Escolà Casas ,&nbsp;Anna von Wichert ,&nbsp;Rocío Inés Bonansea ,&nbsp;Jochen Kuckelkorn ,&nbsp;Miren López de Alda ,&nbsp;Víctor Matamoros","doi":"10.1016/j.envpol.2025.127202","DOIUrl":"10.1016/j.envpol.2025.127202","url":null,"abstract":"<div><div>Hydroponic agriculture combined with reclaimed water use represents a sustainable strategy to address global water scarcity. However, the presence of persistent, mobile, and toxic (PMT) substances in reclaimed water raises emerging concerns for environmental safety and food security. This study examines the impact of five concentration levels (0.05–500 μg L⁻¹) of a nine-compound PMT mixture, including venlafaxine, O-desmethyl venlafaxine, ofloxacin, terbutryn, 1H-benzotriazole, (4 + 5)-methylbenzotriazole, galaxolidone, perfluorobutanesulfonic acid (PFBS), and perfluoropentanoic acid (PFPeA), on hydroponically cultivated lettuce under controlled greenhouse conditions. A multidisciplinary assessment was conducted, including contaminant uptake and bioaccumulation, agronomic performance, plant metabolomics, in-vitro toxicological bioassays, and a theoretical human health risk assessment. Results showed compound-specific accumulation, with PFPeA and galaxolidone reaching 559 and 483 ng g⁻¹ fresh weight, respectively. Agronomic effects ranged from hormetic responses at environmentally relevant low concentrations to phototoxic stress at higher exposures. Although no effects were detected in toxicological bioassays, PFPeA exceeded risk thresholds (HQ = 1–25) at concentrations ≥50 μg L⁻¹, indicating potential concern for human exposure via vegetable crop consumption. These findings underscore the need for environmentally realistic dose–response studies to inform regulatory thresholds and ensure the safe use of reclaimed water in food production systems.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"386 ","pages":"Article 127202"},"PeriodicalIF":7.3,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145209355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Weathered microplastics alter deep sea benthic biogeochemistry and organic matter cycling: insights from a microcosm experiment","authors":"Claudia Dessì ,&nbsp;Stefano Aliani ,&nbsp;Vincenzo Donnarumma ,&nbsp;Maria Cristina Follesa ,&nbsp;Davide Moccia ,&nbsp;Giuseppe Suaria ,&nbsp;Andrea Paluselli ,&nbsp;Alessandro Cau","doi":"10.1016/j.envpol.2025.127209","DOIUrl":"10.1016/j.envpol.2025.127209","url":null,"abstract":"<div><div>The deep seafloor is the largest reservoir for plastic contamination; yet, it remains unclear whether Carbon introduced through synthetic polymers might alter key ecosystem functions. We assessed the potential alterations in organic matter (OM) cycling triggered by a pulse-injection of microplastics (MPs) into deep sea sediments collected from the upper bathyal zone at 530 m depth. Sediments were exposed for 15, 30 and 45 days to environmentally relevant concentrations (∼0.25 % in weight) of naturally weathered MPs (size range 70–210 μm) of polyethylene, tyre wear particles, and a mixture of polymers. Weathered MPs significantly affected the semi-labile fractions of sedimentary OM and extracellular enzymatic activities, ultimately impairing carbon degradation and turnover rates. Polymer-specific effects were observed in carbohydrate and lipid contents, as well as in the activities of alkaline phosphatase and β-glucosidase, with tyre wear particles exerting the most intense impact. Notably, the polymer mixture triggered a less intense effect compared to the same concentration of single polymers. This study highlights how MP contamination can disrupt biogeochemical cycles in deep-sea soft bottoms. Given that these ecosystems constitute the largest portion of the oceans’ seafloor, impacts here documented may signal possible cascading effects throughout the ecological hierarchy. Further research is needed to fully understand the dynamics and effects triggered by substantial accumulation of plastic-derived Carbon in these ecosystems.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"386 ","pages":"Article 127209"},"PeriodicalIF":7.3,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145209360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Co-exposure to polystyrene nanoplastics and glyphosate promotes intestinal apoptosis in mice via intestinal barrier impairment and immunoinflammatory dysregulation","authors":"Beining Wu ,&nbsp;Han Liu ,&nbsp;Ruoyu Dong,&nbsp;Haoyu Xu,&nbsp;Jingyi Qi,&nbsp;Huimei Liang,&nbsp;Chen Guo,&nbsp;Huan Zeng,&nbsp;Jinghua Zhao,&nbsp;Houhui Song,&nbsp;Yongchun Yang,&nbsp;Wei Wang","doi":"10.1016/j.envpol.2025.127206","DOIUrl":"10.1016/j.envpol.2025.127206","url":null,"abstract":"<div><div>Environmental contaminants such as polystyrene nanoplastics (PSNPs, 1–1000 nm) and glyphosate pose significant environmental and public health risks. This study aimed to investigate the intestinal toxicity and molecular mechanisms induced by PSNPs and/or glyphosate. Mice were exposed to PSNPs (&lt;100 nm), glyphosate, or a combination of both for 35 days via intragastric administration (PSNPs: 0.5 mg/d; glyphosate: 50 mg/kg-bw/day; PSNPs + glyphosate: 0.5 mg/d +50 mg/kg-bw/day). The control group received same volume of distilled water. Our findings revealed that exposure to PSNPs and/or glyphosate aggravated pathological alterations, including inflammatory cell infiltration, severe mitochondrial cristae fracture, and an approximately 50 % reduction in goblet cells in the intestine. Moreover, exposure to PSNPs and/or glyphosate caused a critical 75 % inhibition of FOXP3 and dissociation of tight junctions in the intestine (reflected by a 50 % decrease in Occludin, and a 20 %–50 % decrease in ZO-1). These changes were accompanied by significant alterations in beneficial gut microbiota, metabolic profiles, bile acid metabolism disorders, and a pronounced elevation in 3-β-deoxycholic acid, a metabolite tied to bile acid receptor signaling and barrier dysfunction. Although exposure to glyphosate led to the most significant upregulation of the pro-inflammatory factors TNF-α and the pro-apoptosis proteins Cleave-caspase-3, co-exposure did not exacerbate cell apoptosis in animal tissue experiments, which is contrasts with the cell-based findings. MODE-K (mouse intestinal epithelial) cells were treated with PSNPs (0.75 mg/mL) or glyphosate (0.5 mg/mL). In vitro experiments showed that PSNPs aggravated the disrupted Treg/Th17 immune-inflammatory balance, impaired intestinal barrier function (with a 50 % reduction in ZO-1 and Occludin), and increased cell apoptosis, caused by glyphosate. This study advances our understanding of the health risks posed by endocrine-disrupting chemical mixtures and provides critical insights into the molecular mechanisms of PSNP-glyphosate-induced intestinal toxicity. These findings lay the groundwork for future research aimed at mitigating the pathophysiological impacts of environmental pollutants.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"386 ","pages":"Article 127206"},"PeriodicalIF":7.3,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145209358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perfluorooctanesulfonic Acid Facilitates the Migration of Choriocarcinoma Cell Line BeWo: Integrins as Potential Target","authors":"Jing Li, Maoxing Pan, Qingyuan Dai, Yongfeng Deng, Shuqin Tang, Hongli Tan","doi":"10.1016/j.envpol.2025.127210","DOIUrl":"https://doi.org/10.1016/j.envpol.2025.127210","url":null,"abstract":"The migration of placental trophoblasts is a crucial biological process essential for the maintenance of pregnancy. Perfluorooctanesulfonic acid (PFOS), a prototypical per- and polyfluoroalkyl substance, has been linked to a variety of adverse pregnancy outcomes. However, the regulatory effects and molecular mechanisms of PFOS on trophoblast migration, particularly at concentrations reflective of human internal exposure, remain inadequately explored. In this study, we utilized the BeWo choriocarcinoma cell model to evaluate PFOS effects on trophoblast migration at human internal exposure concentrations (0.02 μM, 0.2 μM, and 2.0 μM). Our findings reveal that PFOS significantly promotes trophoblast migration in a dose−dependent manner. Mechanistic profiling identified dysregulated activation of the extracellular matrix (ECM)-receptor interaction pathway and metabolic reprogramming, notably in amino acid metabolism, as potential drivers of this promoted migration. Further, integrin α5 (ITGA5), α3 (ITGA3), and α2 (ITGA2) were identified as putative molecular targets of PFOS. These findings, despite originating from BeWo choriocarcinoma cells model, provide novel mechanistic insights into the link between environmental PFOS exposure and placental dysfunction, thereby contributing to our understanding of the molecular basis underlying PFOS-associated pregnancy complications.","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"4 1","pages":""},"PeriodicalIF":8.9,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145216201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive Screening and Occurrence-Removal Assessment of Pharmaceuticals and Personal Care Products in Wastewater Treatment Plants Using High-Resolution Mass Spectrometry","authors":"Mengkai Yang, Langjie Ye, Bing Du, Weikun Meng, Wei Liu, Guanyong Su","doi":"10.1016/j.envpol.2025.127201","DOIUrl":"https://doi.org/10.1016/j.envpol.2025.127201","url":null,"abstract":"The extensive use of pharmaceuticals and personal care products (PPCPs) has led to their increasing presence in urban wastewater. The discharge of these contaminants into natural water bodies poses a threat to human health and the ecological environment. This study developed an integrated targeted, suspect, and functional group-dependent screening method for PPCPs via UHPLC-Q-Orbitrap HRMS, and this method was applied for investigation of occurrence of known and unknown PPCPs in 90 water samples from 18 wastewater treatment plants (WWTPs) located along the Yangtze River. The results demonstrated that 39 target PPCPs were detected in at least one of the analyzed samples, and it was worth noting that sulfadimethoxine (SDM) exhibited a detection frequency of 100% with a concentration range of 1.48 to 67,400 ng/L. We also observed that water samples from different treatment processes exhibited different contamination profiles of PPCPs. On the basis of concentrations of PPCPs detected in water samples, the overall removal efficiency of PPCPs was preliminarily calculated to be 85.3% for the WWTPs. The treatment processes had a significant effect on the overall removal of the 39 PPCPs (Mann–Whitney U test, <em>p</em> &lt; 0.001). Through suspect screening, a total of 1632 compounds were detected, with three successfully identified; through nontarget screening, 18 unknown PPCPs were identified. This study provided an efficient technique for comprehensive screening of known and unknown PPCPs in environments, and further explored the concentration differences of PPCPs during various treatment processes in WWTPs.","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"695 1","pages":""},"PeriodicalIF":8.9,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145209357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From particle tracking modelling to species impact forecasting: a framework for microplastic exposure risk quantification in the largest freshwater lake of China","authors":"Weihao Yuan ,&nbsp;Tao Long ,&nbsp;Yichuan Zeng ,&nbsp;Yanqing Deng ,&nbsp;Hua Wang","doi":"10.1016/j.envpol.2025.127211","DOIUrl":"10.1016/j.envpol.2025.127211","url":null,"abstract":"<div><div>Microplastics (MPs) are among the most widely studied pollutants, yet their transport pathways and mass concentrations have been relatively unexplored using numerical modelling in aquatic environments. In this study, we investigated the transport dynamics, spatial distribution, and impact levels of MPs in Poyang Lake, China's largest freshwater lake, utilizing a hydrodynamic model coupled with the particle tracking module. An improved risk matrix approach was applied to semi-quantitatively assess the Species Impact Index (<span><math><mrow><mi>S</mi><mi>I</mi><mi>I</mi></mrow></math></span>) of MPs on Finless Porpoises and Siberian White Cranes. This study showed that PA/PVC particles were largely retained outside the main basin, while PP/PE particles entered the central lake with shape- and density-dependent lag times. PE settled faster and exhibited longer retention than PP, with high-surface-area morphotypes (e.g., fibres, films) accelerating sedimentation through biofilm-mediated density increase. Spatially heterogeneous MP accumulation occurred in resuspension-prone regions driven by complex bathymetry and hydrodynamics. <span><math><mrow><mi>S</mi><mi>I</mi><mi>I</mi></mrow></math></span> results indicated significant spatial overlap between MP footprints and critical habitats of the sensitive species, with PP/PE fibres and foams posing Grade III (significant) risks in northern and southwestern subregions. Based on the evaluation results, targeted recommendations were proposed for the management and control of MPs in Poyang Lake, providing a protective framework for lake administrators.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"386 ","pages":"Article 127211"},"PeriodicalIF":7.3,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145216199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}