Yi Wu, Zongwei Wang, Ziyu Xue, Yuhang Yan, Bushra Huma, Yuqian Zhou, Zhongxin Tan
{"title":"Fertilization of potentially toxic element-contaminated soils remediated with reusable biochar pellets using rice straw, pig manure and their derived biochar","authors":"Yi Wu, Zongwei Wang, Ziyu Xue, Yuhang Yan, Bushra Huma, Yuqian Zhou, Zhongxin Tan","doi":"10.1016/j.envpol.2024.125551","DOIUrl":"https://doi.org/10.1016/j.envpol.2024.125551","url":null,"abstract":"Potentially toxic elements (PTEs) are widespread pollutants in agricultural fields, presenting significant challenges to the maintenance of soil ecological functions while simultaneously reducing their concentrations. This study detailed the development of a high-strength reusable silicate magnetic composite biochar sphere (SMBCS) characterized by superior magnetic and adsorption properties, synthesized from natural minerals and biochar. The application of SMBCS over three consecutive remediation cycles led to reductions in cadmium (Cd), lead (Pb), and arsenic (As) concentrations in soil by 28.6%, 26.6%, and 42.9%, respectively, accompanied by corresponding decreases in bioavailability of 52.7%, 49.4%, and 39.4%. The accumulation of Cd, Pb, and As in rice seedlings cultivated in the remediated soil decreased by 79.50-85.47%, 38.05-38.99%, and 39.56-77.10%, respectively. However, the removal of essential mineral nutrients (Al, Fe, K, Ca, Mg, Si, N, Zn, Mn, and Cu) from the soil ranged from 3.26% to 36.28%, which adversely affected seed germination and rice seedling growth. Pre-planting fertilization with rice straw (RS), pig manure (PM), biochar (RSB and PMB), and regenerated SMBCS (RSMBCS1 and RSMBCS2) effectively reduced Cd (0.20-45.40%) and Pb (8.70-35.36%) uptake while enhancing the bioavailability of mineral nutrients, thereby promoting crop growth and physiological traits. The SMBCS-fertilization technique emerges as a viable approach for the removal of PTEs in agricultural soils, facilitating the restoration of ecological functions and ensuring safe agricultural production.","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"17 1","pages":""},"PeriodicalIF":8.9,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142832423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shanshan Chen, Shiquan Chen, Zhenghua Tao, Yanping Li, Paolo Magni, Li Zhang, Xinqing Zheng, Ke Pan
{"title":"The importance of organic matter in controlling the metal variability and mobility in seagrass sediments","authors":"Shanshan Chen, Shiquan Chen, Zhenghua Tao, Yanping Li, Paolo Magni, Li Zhang, Xinqing Zheng, Ke Pan","doi":"10.1016/j.envpol.2024.125542","DOIUrl":"https://doi.org/10.1016/j.envpol.2024.125542","url":null,"abstract":"Metal contamination in seagrass beds has been extensively studied in the past decades. Most of earlier studies have focused on reporting metal concentration in different compartments of seagrass ecosystem, with little attention given to the role of sediment organic matter in controlling the metal mobility and bioavailability. This study investigated metal contamination in seagrass sediments in Hainan Island, China and illustrated how various geochemical factors impact the spatial variability of the metal concentrations. Particularly, we explored how organic matter influence metal storage and mobility in the seagrass sediments. The enrichment of metals in these sediments was not only associated with levels of organic matter but also their sources. The organic matter content showed positive correlations with both metal concentrations and acid-extractable fractions of chromium, silver, and cadmium, highlighting its significant role in influencing metal accumulation and mobility in sediments. Overall, this research enhances our understanding of metal cycling within seagrass ecosystems and highlights the vital role of seagrass-derived organic matter in regulating metal dynamics.","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"6 1","pages":""},"PeriodicalIF":8.9,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142825732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The catalytic role of Cr(VI) in promoting the degradation of organic pollutants via TiO2/SnO2/BiVO4 photoelectrocatalysis: as an electron transfer carrier","authors":"Xing-Peng Wei, Hong-Gang Ni","doi":"10.1016/j.envpol.2024.125543","DOIUrl":"https://doi.org/10.1016/j.envpol.2024.125543","url":null,"abstract":"Regarding the coexistence of heavy metals and organic pollutants, many studies have achieved synergistic removal of Cr(VI) and organic pollutants under acidic conditions. However, the role of Cr(VI) in the removal of organic pollutants under neutral conditions may have been overlooked. Here, the catalytic effect of Cr(VI) in promoting the photoelectrocatalytic degradation of organic pollutants was investigated using a ternary system, which was a combination of photocatalysis, electrocatalysis and Cr(VI) catalysis. A fabricated TiO<sub>2</sub>/SnO<sub>2</sub>/BiVO<sub>4</sub> composite was used as an anode for degradation experiments. We found that the degradation efficiency and final removal of rhodamine B (RhB), ofloxacin (OFL), and tetracycline (TC) were improved by increasing the Cr(VI) concentration within the range of 10 to 20 mg L<sup>-1</sup>. And the addition of Cr(VI) sharply improved the removal of the three organic pollutants under the optimal conditions (from 65% to 96% for RhB, from 34% to 81% for OFL, and from 43% to 100% for TC). According to the results of different processing methods and quenching experiments, we proposed a new catalytic mechanism that, Cr(VI) promotes PEC degradation by acting as an electron transfer carrier between TiO<sub>2</sub>/SnO<sub>2</sub>/BiVO<sub>4</sub> and O<sub>2</sub>.","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"38 1","pages":""},"PeriodicalIF":8.9,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142825733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fátima Jesus, Filipa Mesquita, Dalila Serpa, Elisa Virumbrales Aldama, Luísa Magalhães, Ana Ré, Isabel Campos, Nelson Abrantes, Joana L. Pereira, Fernando J.M. Gonçalves, António J.A. Nogueira, Ana M.M. Gonçalves
{"title":"Effects of wildfire ash on the fatty acid and sugar profiles of bivalves – a comparative study of a freshwater and a marine species","authors":"Fátima Jesus, Filipa Mesquita, Dalila Serpa, Elisa Virumbrales Aldama, Luísa Magalhães, Ana Ré, Isabel Campos, Nelson Abrantes, Joana L. Pereira, Fernando J.M. Gonçalves, António J.A. Nogueira, Ana M.M. Gonçalves","doi":"10.1016/j.envpol.2024.125540","DOIUrl":"https://doi.org/10.1016/j.envpol.2024.125540","url":null,"abstract":"Wildfires can impact both freshwater and marine ecosystems through post-fire runoff, but its effects on bivalves, particularly those living in marine habitats, remain largely overlooked. While evidence exists that wildfire ash can alter the fatty acid (FA) and sugar profiles of aquatic biota, its influence on the biochemical profiles of bivalves have not been addressed to date. This study aimed to assess the effects of ash exposure on the FA and sugar profiles of two bivalve species used for human consumption: a freshwater clam (<em>Corbicula fluminea</em>) and a marine bivalve (<em>Cerastoderma edule</em>), additionally evaluating potential effects on their nutritional value. Both species were exposed to environmentally relevant concentrations of aqueous extracts of Eucalypt ash (AEAs) for 96 hours. Results showed species-specific responses to ash extracts exposure, with more pronounced effects on C<em>. edule</em>. This species exhibited a trend for reduced FA content, statistically significant for C17:0 but also evident for unsaturated FAs, which is relevant for human health as they represent a decrease in the nutritional value. Conversely, an increase in the sugar content of this species was observed with increasing AEA concentrations, despite only statistically significant for galactose and xylose. In contrast, the clams exhibited only minor effects, showing a trend for increased FA and decreased sugar contents, but only significant for the monounsaturated FA content. This study suggests a higher sensitivity of marine bivalves to wildfire ash compared to their freshwater counterparts. Moreover, it highlights, for the first time, the potential of post-fire runoff to alter the biochemical profiles of bivalve species, raising concerns about broader impacts on aquatic trophic webs and human health, an issue that becomes particularly relevant given the forecasted increase in wildfire’s frequency and extension due to global warming.","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"1243 1","pages":""},"PeriodicalIF":8.9,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142832368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Environmental PollutionPub Date : 2024-12-15Epub Date: 2024-08-15DOI: 10.1016/j.envpol.2024.124756
Emily A Strong, Sarah L Crowley, Julia L Newth, Michelle F O'Brien, Rosa Lopez Colom, Sean A Davis, Ruth L Cromie, Stuart Bearhop, Robbie A McDonald
{"title":"Spatial and temporal variation in the prevalence of illegal lead shot in reared and wild mallards harvested in England.","authors":"Emily A Strong, Sarah L Crowley, Julia L Newth, Michelle F O'Brien, Rosa Lopez Colom, Sean A Davis, Ruth L Cromie, Stuart Bearhop, Robbie A McDonald","doi":"10.1016/j.envpol.2024.124756","DOIUrl":"10.1016/j.envpol.2024.124756","url":null,"abstract":"<p><p>The use of lead shotgun ammunition for shooting wildfowl has been restricted in England since 1999, but surveys finding lead shot in harvested birds show compliance with regulations has been low. Following the announcement in 2020 of a voluntary transition from lead to non-lead shot by UK shooting organizations, we investigated spatiotemporal variation in the composition of ammunition used for shooting mallards Anas platyrhynchos. We collected 176 harvested mallards during the 2021/22 shooting season and analyzed recent shot extracted from carcasses to determine shot composition. Using a separate collection of ducks of known provenance, we used stable isotope analysis as a means of differentiating captive-reared from wild mallards. This allowed us to understand how compliance might vary between driven game shooters, characterized by shooting birds that are flushed over a stationary line of shooters, and who primarily harvest captive-reared and released ducks, and wild duck shooters. Of 133 mallards containing recent shot, 92 (69%) had been illegally shot with lead. Analysis of this and five comparable surveys between 2001 and 2019 indicates regional and temporal variation in lead shot presence in England. In the North West and West Midlands, the likelihood of mallards containing lead shot decreased significantly over time, but no other regions showed significant changes. The use of non-lead shot types varied over time, with increases in steel shot use approximately matched by declines in bismuth shot. Mallards likely to be reared were more likely to have been shot with lead (75%) than those likely to be wild (48%). This suggests the use of lead shot is more frequent among driven game shooters than wild duck shooters. In England in 2021/22, most mallards continued to be shot with lead, suggesting that neither legislation nor voluntary approaches have been effective in substantially reducing illegal use of lead shot.</p>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":" ","pages":"124756"},"PeriodicalIF":7.6,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141994868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xunrong Huang, Kun Chen, Chenxi Wang, Pengcheng Gao
{"title":"Characteristics of fluoride adsorption in different soil types: potential factors and implications for environmental risk assessment","authors":"Xunrong Huang, Kun Chen, Chenxi Wang, Pengcheng Gao","doi":"10.1016/j.envpol.2024.125537","DOIUrl":"https://doi.org/10.1016/j.envpol.2024.125537","url":null,"abstract":"The adsorption of fluoride by soils influences its mobility and bioavailability. Therefore, the fluoride adsorption process in soils has garnered widespread attention. Yet research on assessing environmental risk based on the characteristics of fluoride adsorption in soil is still limited. Here, a suite of batch experiments were conducted using three soil types with distinct properties. The results demonstrate that soil organic matter (SOM) and pH are critical factors determining fluoride adsorption in soils. Paddy soil (PS) with its higher SOM content has a higher adsorption capacity compared with loessal soil (LS) and brown soil (BS). Under acidic conditions, BS and LS whose Ca<sup>2+</sup> content is higher exhibited a higher adsorption capacity. The fluoride adsorption process in soils may involve electrostatic adsorption, complexation, and precipitation. The desorption results showed stronger fluoride binding to PS and LS than BS, while the fluoride adsorbed onto BS was almost completely desorbed. This research demonstrates that a deeper understanding of regional differences in soil properties is crucial for better studying the migration and accumulation characteristics of fluoride and its bioavailability in various soils. This study provides a theoretical basis for evaluating the bioavailability, exposure risk, and groundwater pollution risk of fluoride in different soils.","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"83 1","pages":""},"PeriodicalIF":8.9,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142823243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Giannessi, V. Meucci, L. Intorre, A. Cuccaro, R. Freitas, L. De Marchi, G. Monni, M. Baratti, Pretti C
{"title":"Combined effects of fluoroquinolone antibiotic enrofloxacin and rising sea temperatures on the health of the Mediterranean mussel (Mytilus galloprovincialis): exploring physiological, biochemical, and energetic balance dynamics.","authors":"J. Giannessi, V. Meucci, L. Intorre, A. Cuccaro, R. Freitas, L. De Marchi, G. Monni, M. Baratti, Pretti C","doi":"10.1016/j.envpol.2024.125500","DOIUrl":"https://doi.org/10.1016/j.envpol.2024.125500","url":null,"abstract":"Human activity exposes organisms in marine ecosystems to numerous stressors, including rising seawater temperatures and antibiotic contamination. The present study investigated the impacts of environmentally relevant concentrations of the fluoroquinolone (FQ) antibiotic enrofloxacin (ENR), specifically 5 and 500 ng/L, in <em>Mytilus galloprovincialis</em> under ambient (20 °C) and predicted warming (25 °C) conditions after 14 days of exposure, followed by a 14-day recovery period in the absence of ENR. The chemical analyses revealed significant variability in bioaccumulation in mussel tissues. Physiological assessments showed decreased respiration and filtration rates post-exposure, with temperature-dependent recovery dynamics. Biochemical parameters indicated an increased metabolic capacity and energy reserves at higher temperatures, with a significant increase in energy expenditure. Notably, ENR induced significant DNA single-strand breaks in mussel gills and digestive glands, with temperature influencing DNA repair mechanisms. The combination of ENR and elevated temperatures exhibited additive or even synergistic effects on certain physiological and biochemical parameters, indicating a higher risk when these stressors act together. The Indipendent Action model (IA) results highlighted that the majority of observed effects in combined stressors were consistent with predicted values, with notable synergistic interactions in energy reserves and antagonistic responses in metabolic and physiological functions. These findings suggest that both stressors, acting alone and especially in combination, may pose a risk to marine bivalves such as mussels. Further research is needed to assess the impacts of FQs and ocean warming on ecosystem stability and non-target organisms.","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"117 1","pages":""},"PeriodicalIF":8.9,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142823246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"6-PPD quinone causes lipid accumulation across multiple generations differentially affected by metabolic sensors and components of COMPASS complex in Caenorhabditis elegans","authors":"Yuxing Wang, Jingwei Wu, Dayong Wang","doi":"10.1016/j.envpol.2024.125539","DOIUrl":"https://doi.org/10.1016/j.envpol.2024.125539","url":null,"abstract":"The toxicity of 6-PPD quinone (6-PPDQ) has been frequently detected. However, the possible transgenerational effects of 6-PPDQ remain largely unclear. Due to short life cycle and high sensitivity to environmental exposure, <em>Caenorhabditis elegans</em> is useful for study of transgenerational toxicology. In <em>C. elegans</em>, we observed the transgenerational increase in lipid accumulation after parental generation (P0-G) exposure to 6-PPDQ at 0.1-10 μg/L belong to environmentally relevant concentrations. Accompanied with this, transgenerational increase in expressions of genes governing fatty acid synthesis and monounsaturated fatty acyl-CoAs synthesis and decrease in genes governing fatty acid β-oxidation were induced by 6-PPDQ exposure. Moreover, 6-PPDQ exposure at P0-G caused transgenerational activation of <em>mdt-15</em> and <em>sbp-1</em> encoding lipid metabolic sensors. Meanwhile, exposure to 6-PPDQ induced transgenerational activation of <em>set-2</em> and inhibition in <em>rbr-2</em>, two genes encoding components of COMPASS complex. The 6-PPDQ induced transgenerational lipid accumulation could be strengthened by RNAi of <em>set-2</em> and suppressed by RNA interference (RNAi) of <em>rbr-2</em>. Additionally, 6-PPDQ induced transgenerational neurotoxicity could be increased by RNAi of <em>mdt-15</em>, <em>sbp-1</em>, and <em>rbr-2</em>, and inhibited by RNAi of <em>set-2</em>. Therefore, our results demonstrated the possibility in resulting in transgenerational lipid accumulation by exposure to 6-PPDQ.","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"74 1","pages":""},"PeriodicalIF":8.9,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142823250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Adsorption behavior of commercial biodegradable plastics towards pollutants during the biodegradation process: Taking starch-based biodegradable microplastics, oxytetracycline and Cu (II) as examples","authors":"Liuyu Chen, Ying Sun, Xuejiang Wang, Siqing Xia, Jianfu Zhao","doi":"10.1016/j.envpol.2024.125538","DOIUrl":"https://doi.org/10.1016/j.envpol.2024.125538","url":null,"abstract":"With the widespread use of biodegradable plastic bags, their potential environmental risks need further assessment. This study focused on commercial starch-based blended biodegradable microplastics (70% Poly(butylene adipate-<em>co</em>-terephthalate) (PBAT)+5% Poly(lactic acid) (PLA)+20% Thermoplastic starch (TPS), PPT MPs) to investigate their adsorption behaviors towards Cu(II) and oxytetracycline (OTC) under microbial colonization and biodegradation. Post-biodegradation, the hydroxyl (–OH) peak intensity of starch in PPT significantly decreased, while carbonyl (C=O) peaks of PBAT and PLA broadened, with O/C ratio rising from 14.65% to 35.82%. The starch’s degradation in PPT altered its thermal properties. Microbial colonization on PPT (B-PPT) enhanced Cu(II) and OTC adsorption, while biodegradation (D-PPT) reduced their adsorption. Reduced surface carbonyl and hydroxyl groups, alongside increased crystallinity, diminished D-PPT’s Cu(II) adsorption. While OTC adsorption, driven by hydrophobic partitioning, was less affected by biodegradation. In the binary pollutant system, the Cu(II) and OTC adsorption of D-PPT increased by 20.27% and 8.63 times, respectively; B-PPT showed decreased adsorption of both. Coexisting organic matter and pH significantly affected PPT’s adsorption behavior by altering Cu(II) and OTC speciation, and influencing adsorption competition, hydrogen bonding and bridging effects. This study is the first to explore biodegradation impacts of commercial starch-based microplastics on typical heavy metals and antibiotics adsorption, providing important theoretical insights for understanding their environmental risks.","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"22 1","pages":""},"PeriodicalIF":8.9,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142825734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Polycyclic aromatic hydrocarbons exposure in early pregnancy on child neurodevelopment","authors":"Zhi Li, Yu Han, Xinyu Li, Wenjuan Xiong, Tingkai Cui, Wei Xi, Shihao Jin, Xin Zhang","doi":"10.1016/j.envpol.2024.125527","DOIUrl":"https://doi.org/10.1016/j.envpol.2024.125527","url":null,"abstract":"The epidemiological evidence from studies on the impact of exposure to polycyclic aromatic hydrocarbons (PAHs) during pregnancy on child neurodevelopment is inconclusive. This study aimed to assess the associations of PAHs exposure in early pregnancy and neurodevelopmental outcomes in children aged 6-12 months in a prospective cohort. In this study, we included 172 mother-child pairs with complete data in Tianjin City, China. Ten PAH metabolites were determined in early-pregnancy urine using gas chromatography and tandem mass spectrometry (GC–MS/MS). Child neurodevelopment was measured using the Griffiths Development Scales-Chinese (GDS-C) when children were between 6 and 12 months old. We employed multivariable linear regression, Weighted Quantile Sum (WQS) regression, and Bayesian Kernel Machine Regression (BKMR) to assess the relationships of individual PAH metabolites and mixtures of these metabolites with child neurodevelopment. Multiplicative interactions were analyzed to examine effect modification by child sex. In the multivariable linear regression analysis, six PAH metabolites were found to be negatively associated with personal social scores, while three PAH metabolites showed a negative association with language scores. The Weighted Quantile Sum (WQS) model revealed that the PAH mixture was linked to decreased personal social scores (β = - 4.18, 95% CI = -7.56, - 0.80) and language scores (β = - 4.17, 95% CI = -7.98, -0.37). Furthermore, the Bayesian Kernel Machine Regression (BKMR) models also indicated the negative associations between the PAHs mixture and personal social scores and language scores. Notably, three PAH metabolites (1-hydroxynaphthalene(1-OHNap),3-hydroxyfluorene(3-OHFlu), 3+9-hydroxyphenanthrene(3+9-OHPhe)) were identified as important contributors to these associations. All analyses of interactions were null. Exposure to PAHs during early pregnancy, whether individually or as a mixture, demonstrated a negative association with child neurodevelopment outcomes.","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"9 1","pages":""},"PeriodicalIF":8.9,"publicationDate":"2024-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142820866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}