Electrochemistry Communications最新文献_第7页

N-doped clay-like Ti3C2Tx MXene/N-doped CNTs composites for ethylene glycol detection in ambient air and exhaled breath 用于检测环境空气和呼出气体中乙二醇的 N 掺杂粘土状 Ti3C2Tx MXene/N 掺杂 CNTs 复合材料

IF 5.4 3区工程技术

Electrochemistry Communications Pub Date : 2024-05-03 DOI: 10.1016/j.elecom.2024.107738

Zhiwen Shi , Lijuan Qiao , Mei Ma , Zhi Jia , Bingxin Liu , Li Gao

{"title":"N-doped clay-like Ti3C2Tx MXene/N-doped CNTs composites for ethylene glycol detection in ambient air and exhaled breath","authors":"Zhiwen Shi , Lijuan Qiao , Mei Ma , Zhi Jia , Bingxin Liu , Li Gao","doi":"10.1016/j.elecom.2024.107738","DOIUrl":"https://doi.org/10.1016/j.elecom.2024.107738","url":null,"abstract":"<div><p>Ethylene glycol is odorless and harmful to humans. Each year, a large number of fatal cases are caused by ethylene glycol poisoning. Therefore, rapid identification of ethylene glycol is crucial. In this study, clay-like Ti<sub>3</sub>C<sub>2</sub>T<sub>x</sub> MXene exhibits a larger interlayer spacing compared to accordion-like Ti<sub>3</sub>C<sub>2</sub>T<sub>x</sub> MXene, which enhances the gas diffusion channels. Nitrogen doping can increase the active sites of clay-like Ti<sub>3</sub>C<sub>2</sub>T<sub>x</sub> MXene. The introduction of nitrogen-doped carbon nanotubes into N-Ti<sub>3</sub>C<sub>2</sub>T<sub>x</sub> was carried out to enhance selectivity towards ethylene glycol, leading to the formation of N-Ti<sub>3</sub>C<sub>2</sub>T<sub>x</sub> MXene/N-CNTs. The N-Ti<sub>3</sub>C<sub>2</sub>T<sub>x</sub> MXene/N-CNTs exhibits significant selectivity towards the ethylene glycol at room temperature. Meanwhile, the detection limit was 0.3484 ppm, with a shortened response/recovery time of 10.57/6.29 s. Meanwhile, the ethylene glycol sensor device has been prepared through custom-made circuit boards and sensing programs. Moreover, the adsorption and oxidation process of ethylene glycol on N-Ti<sub>3</sub>C<sub>2</sub>T<sub>x</sub> MXene/N-CNTs was explored through in-situ infrared spectroscopy testing. This study revealed that the oxygen vacancies on the surface of N-Ti<sub>3</sub>C<sub>2</sub>T<sub>x</sub> MXene/N-CNTs play a crucial role in the oxidative catalytic detection of ethylene glycol. The strategy of N-Ti<sub>3</sub>C<sub>2</sub>T<sub>x</sub> MXene/N-CNTs provides a new avenue for the detection of ethylene glycol.</p></div>","PeriodicalId":304,"journal":{"name":"Electrochemistry Communications","volume":"164 ","pages":"Article 107738"},"PeriodicalIF":5.4,"publicationDate":"2024-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S138824812400081X/pdfft?md5=9b94d206512b6839d9c2e9c878fe43de&pid=1-s2.0-S138824812400081X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140825981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Local electrochemiluminescence imaging using scanning electrochemical cell microscopy 利用扫描电化学细胞显微镜进行局部电化学发光成像

IF 5.4 3区工程技术

Electrochemistry Communications Pub Date : 2024-04-30 DOI: 10.1016/j.elecom.2024.107737

Yufei Deng , Xiaofan He , Rong Jin , Dechen Jiang , Danjun Fang

{"title":"Local electrochemiluminescence imaging using scanning electrochemical cell microscopy","authors":"Yufei Deng , Xiaofan He , Rong Jin , Dechen Jiang , Danjun Fang","doi":"10.1016/j.elecom.2024.107737","DOIUrl":"https://doi.org/10.1016/j.elecom.2024.107737","url":null,"abstract":"<div><p>In this communication, local electrochemiluminescence (ECL) imaging is achieved using scanning electrochemical cell microscopy (SECCM) to create a localized region for the occurrence of ECL reaction. The system is demonstrated using a droplet at the micropipette that is contact with the prepared Ru-Silica@Au particles at indium tin oxide (ITO) slide. Tri-<em>n</em>-propylamine (TPrA) in the droplet reacts with ruthenium complex in a 10 μm-diameter-region to produce ECL emission, which is recorded by photo multiplier tube (PMT) underneath the ITO slide. By contacting each local region consecutively, the distribution of steady-state current and the related ECL emission at the ITO surface is imaged. The local ECL intensity show an approximately linear dependence with the current, but obvious deviation from the linear curve is observed at some regions. This result suggests that the ECL emission is not only determined by the transferred electron number in the electrochemical reaction, and also affected by local environments at ITO surface. As compared with the traditionally used ECL imaging in the bulk solution, this strategy avoids the cross-talking of ECL emission from nearby regions, and could offer a new way to unveil more molecular mechanism in the ECL reaction.</p></div>","PeriodicalId":304,"journal":{"name":"Electrochemistry Communications","volume":"164 ","pages":"Article 107737"},"PeriodicalIF":5.4,"publicationDate":"2024-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1388248124000808/pdfft?md5=4db0c36668499413e0e49adbf6d77201&pid=1-s2.0-S1388248124000808-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140843747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nanocarbon-assisted chemical etching of Ge(100) in H2O2 在 H2O2 中对 Ge(100) 进行纳米碳辅助化学蚀刻

IF 5.4 3区工程技术

Electrochemistry Communications Pub Date : 2024-04-25 DOI: 10.1016/j.elecom.2024.107735

Junhuan Li, Seiya Yamamoto, Kouji Inagaki, Kenta Arima

{"title":"Nanocarbon-assisted chemical etching of Ge(100) in H2O2","authors":"Junhuan Li, Seiya Yamamoto, Kouji Inagaki, Kenta Arima","doi":"10.1016/j.elecom.2024.107735","DOIUrl":"10.1016/j.elecom.2024.107735","url":null,"abstract":"<div><p>We utilized graphene oxide (GO) flakes as a starting material to conduct nanocarbon (NC)-assisted chemical etching of Ge(100) surfaces in H<sub>2</sub>O<sub>2</sub> solutions. Upon initial etching in H<sub>2</sub>O<sub>2</sub>, a pitted morphology formed beneath the loaded nanocarbon. The etch pits exhibited a tendency to expand, with edges assuming square-like shapes in H<sub>2</sub>O<sub>2</sub> solutions. This phenomenon is reminiscent of an inverted pyramidal structure observed during enhanced etching of a Ge surface loaded with metallic particles, exposing (111) microfacets. As the etching progressed, noticeable lateral etching occurred on the Ge surface. Consequently, the small pits merged to form larger hollows, potentially exceeding the size of the initial GO flake. These etching properties were analyzed based on electrochemical reactions there, or the injection of holes created by the enhanced reduction of H<sub>2</sub>O<sub>2</sub> molecules on nanocarbons, which were compared to those observed when using O<sub>2</sub>-dissolved water as an etchant. Additionally, we provide guidelines for achieving more homogeneous and deeper etch structures using a loaded nanocarbon catalyst in H<sub>2</sub>O<sub>2</sub>.</p></div>","PeriodicalId":304,"journal":{"name":"Electrochemistry Communications","volume":"163 ","pages":"Article 107735"},"PeriodicalIF":5.4,"publicationDate":"2024-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S138824812400078X/pdfft?md5=f80b8d5dfda141a399ad1e76350de614&pid=1-s2.0-S138824812400078X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140782128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Detection of electrocatalytical and -chemical processes by means of in situ flow NMR spectroscopy 通过原位流动核磁共振光谱检测电催化和化学过程

IF 5.4 3区工程技术

Electrochemistry Communications Pub Date : 2024-04-25 DOI: 10.1016/j.elecom.2024.107736

Anastasia Vyalikh , Wolfram Münchgesang , Juan-Jesús Velasco-Vélez

{"title":"Detection of electrocatalytical and -chemical processes by means of in situ flow NMR spectroscopy","authors":"Anastasia Vyalikh , Wolfram Münchgesang , Juan-Jesús Velasco-Vélez","doi":"10.1016/j.elecom.2024.107736","DOIUrl":"https://doi.org/10.1016/j.elecom.2024.107736","url":null,"abstract":"<div><p>In situ studies of electrochemical processes using NMR offer valuable information on reaction mechanisms, kinetics, and species identification, making it a powerful tool in electrochemistry research. In this study, we present the design of an in situ redox-flow NMR cell that allows for a continuous flow of liquid (electrolyte) or gas, application of electrical voltage, and recording of NMR signals. The utility of this setup is demonstrated through two case studies: electrochemical copper deposition on a gold electrode and the electrochemical conversion of carbon dioxide into hydrocarbon products. Specifically, the presence of multicarbon products containing C–C bonds generated during the electrochemical reduction reaction is confirmed in the <sup>2</sup>H NMR spectra in the latter example. These findings highlight the ability of the in situ redox-flow NMR cell to directly monitor reaction intermediates and products, thereby enabling the elucidation of reaction mechanisms for the efficient and selective production of valuable hydrocarbon products through the conversion of CO<sub>2</sub> into value-added chemicals. In contrast to other reported in situ NMR cells, the presented cell is suitable for multiple uses, and allows detecting NMR signals not only from exhaust products but also from those formed on the catalyst surface.</p></div>","PeriodicalId":304,"journal":{"name":"Electrochemistry Communications","volume":"163 ","pages":"Article 107736"},"PeriodicalIF":5.4,"publicationDate":"2024-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1388248124000791/pdfft?md5=66184749e151522bda6f9077a46da81f&pid=1-s2.0-S1388248124000791-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140649118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pt nanorods supported on Nb-doped ceria: A promising anode catalyst for polymer electrolyte fuel cells 掺铌铈上的铂纳米棒：用于聚合物电解质燃料电池的前景广阔的阳极催化剂

IF 5.4 3区工程技术

Electrochemistry Communications Pub Date : 2024-04-23 DOI: 10.1016/j.elecom.2024.107733

Guoyu Shi , Tetsuro Tano , Donald A. Tryk , Akihiro Iiyama , Makoto Uchida , Katsuyoshi Kakinuma

{"title":"Pt nanorods supported on Nb-doped ceria: A promising anode catalyst for polymer electrolyte fuel cells","authors":"Guoyu Shi , Tetsuro Tano , Donald A. Tryk , Akihiro Iiyama , Makoto Uchida , Katsuyoshi Kakinuma","doi":"10.1016/j.elecom.2024.107733","DOIUrl":"https://doi.org/10.1016/j.elecom.2024.107733","url":null,"abstract":"<div><p>For polymer electrolyte fuel cells (PEFCs), platinum nanoparticles supported on carbon black (Pt/C) serve as the commonly used hydrogen anode catalyst, exhibiting high activity for the hydrogen oxidation reaction (HOR), while the carbon support is susceptible to corrosion under PEFC operation. Here, a highly active HOR anode catalyst of Pt nanorod supported on niobium (Nb)-doped ceria without using corrosive carbon support was developed, which exhibits high durability at high potentials associated with hydrogen starvation. The production of hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>), which can degrade the polymer electrolyte membrane, was also found to be significantly suppressed on the Pt nanorod/doped ceria catalyst. Density functional theory (DFT) calculations suggests that the Pt nanorod geometry and interaction with Nb and Ce favor HOR activity and stability while suppressing H<sub>2</sub>O<sub>2</sub> production by modulating the adsorption of key reaction intermediates. This new catalyst has the potential to be used as an anode for high-performance and high-durability PEFCs.</p></div>","PeriodicalId":304,"journal":{"name":"Electrochemistry Communications","volume":"163 ","pages":"Article 107733"},"PeriodicalIF":5.4,"publicationDate":"2024-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1388248124000766/pdfft?md5=7ab0124780b55c97dab84e7c1d853a46&pid=1-s2.0-S1388248124000766-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140643536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Corrosion resistance of Cu-Fe deformation processed in situ alloy in chloride ion environment 原位加工的铜铁变形合金在氯离子环境中的抗腐蚀性能

IF 5.4 3区工程技术

Electrochemistry Communications Pub Date : 2024-04-22 DOI: 10.1016/j.elecom.2024.107734

Lin Xu , Jin Zou , Si-qi Zeng , Jun-wei Liu , Ke-ming Liu , Qiang Hu , Guo-jie Huang

{"title":"Corrosion resistance of Cu-Fe deformation processed in situ alloy in chloride ion environment","authors":"Lin Xu , Jin Zou , Si-qi Zeng , Jun-wei Liu , Ke-ming Liu , Qiang Hu , Guo-jie Huang","doi":"10.1016/j.elecom.2024.107734","DOIUrl":"https://doi.org/10.1016/j.elecom.2024.107734","url":null,"abstract":"<div><p>To assess the corrosion resistance of Cu-Fe deformation in situ alloys in a chloride ion environment, Cu-Fe alloys with varying Fe contents (5 wt%, 10 wt%, and 14 wt%) were prepared using vacuum induction melting, and the impact of Fe content on the corrosion resistance was examined. The corrosion morphology and corrosion products were analyzed, and the corrosion rate, corrosion period, dynamic potential polarization curves, electrochemical parameters, and electrochemical impedance spectra with different Fe contents were determined. However, the corrosion resistance of Cu-Fe alloys initially increased with an increase in Fe content before decreasing, with Cu-10 wt% Fe alloys (95% reduction rate) exhibiting the best corrosion resistance. As the Fe content increased, the amount of primary Fe phase gradually increased and became more densely distributed. This led to an increase in the dense oxide film on the surface, thereby enhancing the corrosion resistance of the material. Moreover, with a further increase in Fe, the primary Fe phase exhibited coarsening and non-uniform distribution. This resulted in the oxide film becoming looser, leading to a decreased corrosion resistance of the alloy.</p></div>","PeriodicalId":304,"journal":{"name":"Electrochemistry Communications","volume":"163 ","pages":"Article 107734"},"PeriodicalIF":5.4,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1388248124000778/pdfft?md5=eef424a38509f12598b7b69a06486d9d&pid=1-s2.0-S1388248124000778-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140643535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A few-minute, simple, and affordable route to functionalized electrodes with DNA 用 DNA 实现功能化电极只需几分钟，既简单又实惠

IF 4.7 3区工程技术

Electrochemistry Communications Pub Date : 2024-04-14 DOI: 10.1016/j.elecom.2024.107729

Shahrzad Nikbin, Abbas Karami, Sadegh Khazalpour

{"title":"A few-minute, simple, and affordable route to functionalized electrodes with DNA","authors":"Shahrzad Nikbin, Abbas Karami, Sadegh Khazalpour","doi":"10.1016/j.elecom.2024.107729","DOIUrl":"10.1016/j.elecom.2024.107729","url":null,"abstract":"<div><div>A key challenge in developing DNA-based electrochemical sensors is the rapid and easy immobilization of DNA on different electrode surfaces. The current methods are often laborious and time-consuming. Here, we present a cost-effective and easy-to-perform method for efficiently functionalizing electrode surfaces with DNA in just a few minutes. Our strategy operates in two simple and rapid steps, regardless of the type of electrode, and avoids complicated and time-consuming procedures. The method uses phosphorothioate (PS) modification as an anchoring agent, which is a more cost-effective alternative to thiol (SH) modification, and eliminates the need for complex pretreatment processes. Additionally, a low-pH DNA loading method was used to quickly bind PS DNA to the gold surface without the need for surface-covering agents. We attributed the effect of low pH to the protonation of adenine (A), which leads to the formation of a parallel poly-A duplex (A motif) and facilitates vertical PS-DNA attachment to the electrode surface. Electrochemical techniques were used to confirm the vertical attachment of DNA to the electrode surface, and evaluation of the adsorption stability and hybridization efficiency confirmed the effectiveness of the method. The simplicity and efficiency of this method make it an ideal solution for researchers who require a fast and reliable method for DNA functionalization of electrode surfaces.</div></div>","PeriodicalId":304,"journal":{"name":"Electrochemistry Communications","volume":"169 ","pages":"Article 107729"},"PeriodicalIF":4.7,"publicationDate":"2024-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140772943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Simultaneous measurement of corrosion potential and hydrogen penetration using double-head scanning Kelvin probe 使用双头扫描开尔文探针同时测量腐蚀电位和氢渗透率

IF 5.4 3区工程技术

Electrochemistry Communications Pub Date : 2024-04-13 DOI: 10.1016/j.elecom.2024.107717

Kiyonobu Sugae , Yasuyo Otsuka , Takayuki Kamimura

{"title":"Simultaneous measurement of corrosion potential and hydrogen penetration using double-head scanning Kelvin probe","authors":"Kiyonobu Sugae , Yasuyo Otsuka , Takayuki Kamimura","doi":"10.1016/j.elecom.2024.107717","DOIUrl":"https://doi.org/10.1016/j.elecom.2024.107717","url":null,"abstract":"<div><p>High-strength steels, such as high-strength bolts or steel plates are considerably sensitive to hydrogen embrittlement. Serious safety problems in steel structures are possible, because they are exposed to atmospheric condition containing chloride ions. Embrittlement is induced by hydrogen penetration during atmospheric corrosion. We developed Double-Head Scanning Kelvin Probe (DHSKP) equipment to clarify the relationship between the corrosion process and hydrogen permeation. Each probe can simultaneously measure the corrosion potential on the corroded side and surface potential on the hydrogen-detecting side at the same time. In this study, we investigated the correlation between the corrosion potential and hydrogen permeation under changing conditions from wet to dry processes on the surface of a steel sample. During the drying process, the corrosion potential at the rust layer that precipitated in the early wetting condition showed a less noble potential locally, whereas the surface potential of the Pd film on the hydrogen detection side showed a less noble potential locally. The hydrogen permeation sites were limited to small spots in the opposite area, where the corrosion potential showed a less noble local-potential during the drying process. Hydrogen penetration by corrosion likely occurs in acidic liquids under the rust layer during the drying process.</p></div>","PeriodicalId":304,"journal":{"name":"Electrochemistry Communications","volume":"163 ","pages":"Article 107717"},"PeriodicalIF":5.4,"publicationDate":"2024-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1388248124000602/pdfft?md5=f9e5c3a06f9be8dad22a5a046c118ff9&pid=1-s2.0-S1388248124000602-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140604665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

On the futility of the Fuoss-Kirkwood relation 福斯-柯克伍德关系的徒劳无益

IF 5.4 3区工程技术

Electrochemistry Communications Pub Date : 2024-04-12 DOI: 10.1016/j.elecom.2024.107731

K.T. Malkow

引用次数: 0

Electrochemical detection of amine neurotransmitters is drastically different in buffer solutions, in vivo, and cell culture systems 胺类神经递质的电化学检测在缓冲溶液、体内和细胞培养系统中存在巨大差异

IF 4.7 3区工程技术

Electrochemistry Communications Pub Date : 2024-04-10 DOI: 10.1016/j.elecom.2024.107732

Samuel Rantataro , Laura Ferrer Pascual , Tomi Laurila

{"title":"Electrochemical detection of amine neurotransmitters is drastically different in buffer solutions, in vivo, and cell culture systems","authors":"Samuel Rantataro , Laura Ferrer Pascual , Tomi Laurila","doi":"10.1016/j.elecom.2024.107732","DOIUrl":"10.1016/j.elecom.2024.107732","url":null,"abstract":"<div><div>Detection of neurotransmitters requires high sensitivity and temporal resolution, favoring electrochemical techniques for the sensing mechanism. However, electrochemical detection of amine neurotransmitters is highly dependent on electrode surface condition and thus, results obtained in clean buffer solutions are not directly applicable to the real measurement environment <em>in vivo</em> or <em>in vitro</em>. In these more complex electrolyte solutions, the presence of antioxidants and surface-adsorbing molecules drastically alters the redox characteristics of amine neurotransmitters, their precursors and metabolites. Accordingly, we surveyed their redox characteristics in the phosphate buffered saline (PBS), cerebrospinal fluid (CSF) and cell culture medium, with high-sensitivity electrodes made of single-walled carbon nanotube network.</div><div>The concentration of surface-fouling molecules was lowest in the PBS and highest in the culture medium. Accordingly, electrochemical reaction kinetics were facile in the PBS and sluggish in the culture medium. Surprisingly, analyte molecular structure had much more importance in the CSF compared to other electrolytes, however the reaction kinetics remained to be generally slower in the CSF compared to when measured in the PBS.</div><div>Whereas the CSF also contains L-Ascorbic acid and uric acid that are electrochemically active interfering molecules, they are either completely absent or can be omitted in the <em>in vitro</em> setting. On the contrast, the culture medium contains substantially higher concentration of surface-adsorbing molecules that causes more significant fouling of electrode and thus loss of sensitivity. As the <em>in vitro</em> brain-on-a-chip applications are rapidly being adopted, direct comparison of these different experimental settings was essential to understand their implications for electrochemical sensors.</div></div>","PeriodicalId":304,"journal":{"name":"Electrochemistry Communications","volume":"169 ","pages":"Article 107732"},"PeriodicalIF":4.7,"publicationDate":"2024-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140790138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0