Dental Materials最新文献

{"title":"Integration of various forms of Salvadora Persica « Siwak » into dental composites: A pilot in vitro study","authors":"Fatma Zohra Cherchali ,&nbsp;Nina Attik ,&nbsp;Halima Meriem Issaadi ,&nbsp;Hazem Abouelleil ,&nbsp;Dominique Decoret ,&nbsp;Amel Amirouche-Korichi ,&nbsp;Mohamed Mouzali ,&nbsp;Dominique Seux ,&nbsp;Brigitte Grosgogeat","doi":"10.1016/j.dental.2025.06.015","DOIUrl":"10.1016/j.dental.2025.06.015","url":null,"abstract":"<div><h3>Objective</h3><div>This study assessed the potential of <em>Salvadora Persica</em> (Siwak) as a natural bioactive agent for developing dental composites with antibacterial and antioxidant properties. The primary aim was to evaluate its efficacy and identify the optimal form whether powder, extract, or fibers, that achieves a balance between bioactivity, mechanical and physical characteristics.</div></div><div><h3>Methods</h3><div>Various forms of Algerian and Oriental Siwak (powder, extracts and fibers), were incorporated at 5 % w/w into experimental dental composites. Flexural strength (FS), flexural modulus (FM) and degree of conversion (DC) were assessed to identify the optimal form. Metabolic activity of <em>Streptococcus mutans</em> in contact with pure Siwak was quantified using the Alamar Blue assay. Antibacterial activity of Siwak-based composites against bacteria was evaluated using turbidity tests, while bacterial cell counts and biofilm formation were analyzed via Scepter™ automated bacteria counter and scanning electron microscopy (SEM), respectively. Antioxidant capacity was determined through the 2, 2-Diphenyl-1-picrylhydrazyl (DPPH) assay.</div></div><div><h3>Results</h3><div>Siwak powder and hot extracts at 5 % incorporation achieved acceptable FS (&gt;85 MPa) and did not affect FM and DC. Siwak-based composites exhibited antioxidant capacities ranging from 6.1 % to 23.4 %, and reduction in bacterial growth of 31.3 %–33.9 %. Hot Algerian Siwak extract was the most effective form. Microwave extracts and fibers negatively affected FS.</div></div><div><h3>Significance</h3><div>Siwak-based dental composites exhibited dual functionality by providing antioxidant properties and inhibiting <em>S. mutans growth without compromising physical and mechanical properties. Siwak biological potential suggest possible application in other dental materials, offering a promising strategy for secondary caries prevention and enhancing restoration longevity.</em></div></div>","PeriodicalId":298,"journal":{"name":"Dental Materials","volume":"41 9","pages":"Pages 1120-1130"},"PeriodicalIF":4.6,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144511288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heating of dental composites: The crucial role of the silane coupling agent on the consistency change","authors":"Benjamin Grob ,&nbsp;Nathan Wachter ,&nbsp;Robert Liska ,&nbsp;Yohann Catel","doi":"10.1016/j.dental.2025.06.022","DOIUrl":"10.1016/j.dental.2025.06.022","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the influence of the nature of silane coupling agents on the consistency of dental composites at various temperatures.</div></div><div><h3>Methods</h3><div>Silanes <strong>SI 1–4</strong> were synthesized in one single step. They were characterized by ¹H and ¹³C NMR spectroscopy. <strong>SI 1–4</strong>, as well as 3-methacryloyloxypropyltrimethoxysilane (MPTS), 8-methacryloyloxyoctyltrimethoxysilane (MOTS) and n-dodecyltrimethoxysilane were then used to functionalize a barium aluminum borosilicate glass filler (d₅₀ = 1.0 µm). Silanizations were carried out in cyclohexane in the presence of a catalytic amount of n-propylamine. Each silane was used in an equimolar amount. Composites containing 67 wt% of silanized fillers and packable composites exhibiting a similar consistency at room temperature were subsequently formulated. The consistency of the uncured composites was determined at various temperatures (23 °C, 30 °C, 50 °C and 60 °C) using a texture analyzer. The flexural strength and modulus of the cured composites were assessed according to ISO 4049.</div></div><div><h3>Results</h3><div>The structure of the silane was shown to strongly influence the consistency of composites. The spacer length between silyl and methacrylate groups, as well as the presence of a urea or a urethane moiety, were demonstrated to be key parameters. Heating of each composite resulted in a drop of the consistency. The decrease was however significantly stronger if coupling agents with long spacers were selected. Especially, the use of <strong>SI 3</strong> provided a packable composite which exhibited a packable consistency at 30 °C and flowable consistency at 60 °C. Regarding mechanical properties, it was shown that the coupling agent must be able to copolymerize with the monomers of the organic matrix to obtain high flexural strength and modulus values. The silanization of glass fillers using silanes bearing a long spacer was shown to have an additional advantage: packable composites having a higher filler content, and consequently improved flexural modulus, can be formulated.</div></div><div><h3>Significance</h3><div>The use of filler particles functionalized with silanes containing long alkyl spacers between the silyl and methacrylate moiety is a promising strategy for the development of packable dental composites which exhibit good mechanical properties and a strong drop in consistency upon heating.</div></div>","PeriodicalId":298,"journal":{"name":"Dental Materials","volume":"41 9","pages":"Pages 1131-1139"},"PeriodicalIF":4.6,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144511287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of the effect of addition/replacement of bioactive glass to hydraulic calcium silicate cement","authors":"Andreas Koutroulis ,&nbsp;Nandita Menon ,&nbsp;Vasileios Kapralos ,&nbsp;Dag Ørstavik ,&nbsp;Maria Pain ,&nbsp;Håkon Valen ,&nbsp;Josette Camilleri ,&nbsp;Anil Kishen ,&nbsp;Pia Titterud Sunde","doi":"10.1016/j.dental.2025.06.018","DOIUrl":"10.1016/j.dental.2025.06.018","url":null,"abstract":"<div><h3>Objectives</h3><div>Assess the effect of addition or replacement of bioactive glass (BG) on the physico-chemical, antibacterial and biological properties of radiopacified tricalcium silicate cement (TCS).</div></div><div><h3>Methods</h3><div>Four materials were tested: An experimental cement with 80 % TCS, 20 % zirconium oxide (TZ-base); two modified versions of TZ-base incorporating 20 % BG 45S5 either as TCS-replacement (TZ-bg-R) or addition (TZ-bg-A); and Biodentine (Septodont). Setting time was assessed using ISO 6876:2012 method. Materials were immersed in water or Dulbecco's modified eagle medium with 10 % fetal bovine serum (DMEM-sup). After seven days, water sorption and solubility were assessed using ISO 4049:2019 methods; water uptake and porosity were also calculated; leachate alkalinity and calcium release were assessed with a pH meter and inductively coupled plasma respectively; specimens were characterized with scanning electron microscopy, energy dispersive X-ray and X-ray diffraction analysis. At one-day, antibacterial properties of material surfaces and leachates were tested against <em>Enterococcus faecalis</em> and <em>Staphylococcus epidermidis</em> biofilms; leachate cytotoxicity and cytokine release were assessed with the 3-(4,5 dimethylthiazolyl-2-yl)-2,5-diphenyl tetrazolium bromide assay and an enzyme-linked immunosorbent assay. Regression models were fitted for all dependent variables.</div></div><div><h3>Results</h3><div>Compared to TZ-base, the BG-containing materials had overall increased water sorption, water uptake and porosity; decreased solubility in DMEM-sup; lower calcium release; and generally similar pH, antibacterial activity, cytotoxicity and cytokine release. All experimental cements were more cytotoxic than Biodentine, but the latter caused higher cytokine release.</div></div><div><h3>Significance</h3><div>The BG-incorporation whether added or replacing the cement decreased the solubility in clinically relevant media and did not deteriorate the antimicrobial and biological properties of the materials.</div></div>","PeriodicalId":298,"journal":{"name":"Dental Materials","volume":"41 9","pages":"Pages 1067-1079"},"PeriodicalIF":4.6,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144504337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of the physicochemical, cytotoxic, and antimicrobial properties of a resin-based pulp capping material incorporated with calcium fructoborate-loaded mesoporous silica nanoparticles","authors":"Hacer Balkaya ,&nbsp;Sezer Demirbuğa ,&nbsp;Serkan Dayan ,&nbsp;Nilay Ildız ,&nbsp;Hatice Bekci","doi":"10.1016/j.dental.2025.06.019","DOIUrl":"10.1016/j.dental.2025.06.019","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aims to evaluate the physicochemical, cytotoxic, and antimicrobial properties of a resin-based pulp capping material incorporating calcium fructoborate-loaded mesoporous silica (SBA-15).</div></div><div><h3>Methods</h3><div>In the study, calcium fructoborate was loaded into mesoporous silica and then incorporated into the resin-based pulp capping material at concentrations of 3 % and 5 % by weight. The study groups were defined as follows: the group without calcium fructoborate-loaded SBA-15 (Control), the group containing 3 % calcium fructoborate-loaded SBA-15 (%3 CF@SBA-15), and the group containing 5 % calcium fructoborate-loaded SBA-15 (%5 CF@SBA-15). The resulting experimental capping materials were then tested for water absorption, solubility, monomer conversion, antibacterial activity, cytotoxicity, and stem cell differentiation.</div></div><div><h3>Results</h3><div>The addition of CF@SBA-15 significantly reduced the material’s water absorption (p &lt; 0.05), while no statistically significant difference was observed between the groups in terms of solubility and monomer conversion (p &gt; 0.05). As the CF@SBA-15 concentration in the material increased, the antibacterial activity against both <em>S. mutans</em> and <em>L. casei</em> significantly improved (p &lt; 0.05). The addition of 3 % and 5 % CF@SBA-15 significantly increased the biocompatibility (p &lt; 0.05). The 5 % CF@SBA-15 group exhibited statistically significantly the highest stem cell differentiation potential, followed by the 3 % CF@SBA-15 group and the control group (p &lt; 0.05). When compared to the control medium, the differentiation level in the CF@SBA-15-containing groups was higher (p &lt; 0.05).</div></div><div><h3>Significance</h3><div>The incorporation of CF@SBA-15 significantly enhanced the biocompatibility and antibacterial properties of the resin-based pulp capping materials. Furthermore, the influence of CF@SBA-15 on stem cell differentiation and its potential to support hard tissue formation in these materials shows promising results.</div></div>","PeriodicalId":298,"journal":{"name":"Dental Materials","volume":"41 9","pages":"Pages 1080-1090"},"PeriodicalIF":4.6,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144504338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fatigue survival rate of resin-bonded zirconia-based ceramics after different surface treatments","authors":"Viviane Cantelli ,&nbsp;Ulysses Lenz ,&nbsp;Jason Alan Griggs ,&nbsp;Alvaro Della Bona","doi":"10.1016/j.dental.2025.06.020","DOIUrl":"10.1016/j.dental.2025.06.020","url":null,"abstract":"<div><h3>Objectives</h3><div>To assess the fatigue survival rate of zirconia-based ceramics (3Y-TZP and 5Y-PSZ) bonded to resin-based cement after various surface treatments, testing the hypotheses that the surface treatments do not affect the fatigue survival rate and that 3Y-TZP has higher fatigue survival than 5Y-PSZ when bonded to a resin-based cement.</div></div><div><h3>Methods</h3><div>Disc-shaped specimens were made from 3Y-TZP (Vita YZ HT) and 5Y-PSZ (Vita YZ XT) monolithic zirconia blocks. The specimens were randomly assigned to six groups according to material and surface treatment: as milled (3Y-None and 5Y-None), silica coating (3Y-Si and 5Y-Si), and airborne-particle abrasion using alumina particles (3Y-AP and 5Y-AP). All zirconia structures were bonded to a fiber-reinforced epoxy resin base (G10). Fatigue test was performed under a 120 N load at a frequency of 3 Hz, and it was discontinued for failure assessment after 10⁴, 10⁵, 5 × 10⁵, 10⁶, and 1.5 × 10⁶ cycles. Presence of any failure was recorded. Representative samples were evaluated under scanning electron microscopy, and the chemical composition was assessed using energy-dispersive spectroscopy (EDS). Fatigue data were analyzed using the Kaplan-Meier (log-rank) and Holm-Sidak methods. Failure modes were determined using fractography principles and statistically assessed using chi-square test.</div></div><div><h3>Results</h3><div>Surface treatments showed significantly different survival curves (p &lt; 0.001) for 5Y-PSZ, but no difference for 3Y-TZP (p = 0.54). Silica coating resulted in a significant difference behavior (p &lt; 0.001) between 3Y and 5Y ceramics. Yet, AP (p = 0.70) and None (p = 0.38) did not influence the survival rates for both ceramics. No significant difference in failure modes was observed among experimental groups (p = 0.30).</div></div><div><h3>Significance</h3><div>The fatigue survival rate of resin bonded 5Y-PSZ was negatively affected by silica coating.</div></div>","PeriodicalId":298,"journal":{"name":"Dental Materials","volume":"41 9","pages":"Pages 1113-1119"},"PeriodicalIF":4.6,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144504336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polymeric nanocarriers doped with a parathyroid hormone-related protein enhances dentin apposition and nanohardness at the resin-dentin interface","authors":"Manuel Toledano ,&nbsp;Fátima S. Aguilera ,&nbsp;Marta Reinoso ,&nbsp;María T. Osorio ,&nbsp;Raquel Toledano ,&nbsp;Christopher D. Lynch ,&nbsp;Estrella Osorio","doi":"10.1016/j.dental.2025.06.017","DOIUrl":"10.1016/j.dental.2025.06.017","url":null,"abstract":"<div><h3>Objectives</h3><div>Restoring the original composition and properties of damaged tissues is aimed by regenerative medicine. The objective of the study was to assess remineralization and bonding capabilities of etched dentin treated with polymeric nanoparticles (NPs) functionalized with parathyroid hormone related proteins (PTHrP).</div></div><div><h3>Methods</h3><div>Dentin etched surfaces were treated with NPs and PTHrP-NPs. The created bonded interfaces were stored for 24 h and further submitted to thermal, chemical and mechanical challenging. Interfaces were assessed through microtensile bond strength, nanohardness, Raman analysis, a fluorescent technique with a confocal laser scanning microscopy, and scanning electron microscopy.</div></div><div><h3>Results</h3><div>Surfaces of dentin treated with PTHrP-NPs and load cycling or immersed in collagenase showed higher bond strength than the other groups. PTHrP promoted the highest nanohardness and phosphate peak intensity at the interface when load cycling was applied. Both porosity and nanoleakage were declined after PTHrP-NPs infiltration. Dentinal tubule walls and hybrid layer showed the strongest signals of xylenol orange stain.</div></div><div><h3>Conclusions</h3><div>The highest dentin bonding efficacy was obtained in samples treated with PTHrP-NPs, as they inducted the greatest remineralization measured by nanoindentation and Raman analysis, high values of bond strength and advanced mineral deposition at the resin-dentin interface and tubules. PTHrP-NPs enabled sealing with scarce nanoleakage and porosity at the interface.</div></div><div><h3>Significance</h3><div>Etched dentin infiltration with hydrophilic polymeric NPs functionalized with parathyroid hormone related proteins, poses an advance in regenerative dentistry, by developing therapeutic bioactivity.</div></div>","PeriodicalId":298,"journal":{"name":"Dental Materials","volume":"41 9","pages":"Pages 1099-1112"},"PeriodicalIF":4.6,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144493211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of biomaterial sandblasting and dentin adhesive strategies on the shear bond strength of CAD/CAM composite resins","authors":"Bérangère Cournault ,&nbsp;Grégoire Hattenberger ,&nbsp;Tatiana Roman ,&nbsp;Hamdi Jmal ,&nbsp;Naji Kharouf ,&nbsp;Olivier Etienne","doi":"10.1016/j.dental.2025.06.021","DOIUrl":"10.1016/j.dental.2025.06.021","url":null,"abstract":"<div><h3>Objective</h3><div>This study aims to compare the effectiveness of two adhesives in bonding CAD/CAM composite resin (CS, Cerasmart 270, GC) prepared using two different sandblasting techniques to human dentin.</div></div><div><h3>Materials and methods</h3><div>Sixty human dentin samples were prepared and treated in etch-and-rinse mode with either the two-bottle G2-BOND Universal (GC) system (G2) or the one-bottle G-Premio BOND (GC) system (GP). CS cylinders were milled and sandblasted based on the alumina particles size used: 50 µm (-50) or 250 µm (-250). Therefore, four distinct groups were obtained: GP-50, G2–50, GP-250, G2–250. A primer (G-Multi PRIMER, GC) was applied on all CS samples before luting to the dentin with G-CEM Link Force (GC). Bond strength (SBS, Universal testing machine, cross-head speed 0.5 mm/min) was measured after 150 days of aging in water, 37°C. A one-way analysis of variance (ANOVA) was used to analyze the roughness, and a two-way ANOVA to analyze the SBS, (SPSSv26, IMB, α=0.05).</div></div><div><h3>Results</h3><div>Sandblasting with a 250 µm particle size created a rougher surface (p &lt; 0.001) with an increased developed area. The G2–250 group showed the greatest SBS values, statistically higher than GP-250 (p = 0.002), while no statistically significant difference was observed in comparison with the other groups. Simple main effects analysis showed that adhesive had a significantly positive effect on SBS results (p = 0.025) while no significant effect was observed for the pretreatment (p = 0.707). Failure mode analysis showed exclusively mixed failures for the G2 group, indicative of robust adhesion, whereas the GP group exhibited mixed and adhesive failures.</div></div><div><h3>Significance</h3><div>The two-step adhesive G2 coupled with macro-sandblasting demonstrated a more robust adhesion.</div></div>","PeriodicalId":298,"journal":{"name":"Dental Materials","volume":"41 9","pages":"Pages 1091-1098"},"PeriodicalIF":4.6,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144482758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physicochemical properties and apatite precipitation behavior of experimental calcium silicate-based cements doped with phosphate compounds","authors":"Kenta Tsuchiya ,&nbsp;Salvatore Sauro ,&nbsp;Hidehiko Sano ,&nbsp;Jukka P. Matinlinna ,&nbsp;Monica Yamauti ,&nbsp;Shuhei Hoshika ,&nbsp;Yu Toida ,&nbsp;Rafiqul Islam ,&nbsp;Atsushi Tomokiyo","doi":"10.1016/j.dental.2025.06.014","DOIUrl":"10.1016/j.dental.2025.06.014","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aims to evaluate the solubility, pH, Ca^2 + release, setting time, and hydroxyapatite (HAp) formation of the tested materials.</div></div><div><h3>Methods</h3><div>Four study groups were tested: NEX-MTA (NMTA; GC, Japan), NMTA with phosphorylated pullulan (MTA-PPL), NMTA with poly-PS (MTA-polyPS), and Biodentine (BD; Septodont, France). Solubility was measured after 7 and 28 days at 37 °C in deionized water. Ca²⁺ release and pH evaluation were performed after immersion in deionized water at 3 h, 24 h, 7 days, and 28 days using pH and Ca²⁺ meters. Setting times were determined with a Vicat apparatus, and apatite precipitation was evaluated through scanning electron microscopy/energy-dispersive X-ray spectroscopy (SEM/ EDS) and Fourier transform infrared spectroscopy (FTIR) analysis 28 days in phosphate-buffered saline.</div></div><div><h3>Results</h3><div>NMTA showed the lowest solubility; however, there was no statistically significant difference between NMTA and MTA-polyPS (P &gt; 0.05)<strong>.</strong> NMTA exhibited the most alkaline pH at all measured time points. Although MTA-polyPS consistently showed lower pH values than NMTA throughout the observation periods, no statistically significant differences were observed among MTA-polyPS, BD, and MTA-PPL at 28 days (P &gt; 0.05). BD released the most Ca²⁺, with MTA-polyPS releasing the least. BD exhibited the shortest initial and final setting time (9.2 and 42 min, respectively), followed by MTA-polyPS, MTA-PPL, and NMTA. SEM/ EDS and FTIR indicated that MTA-polyPS had the highest apatite precipitation, with Ca/P ratios of 1.70 (NMTA) and 1.79 (MTA-polyPS). MTA-PPL and BD showed no significant apatite precipitation, with Ca/P ratios of 3.93 and 34.9, respectively.</div></div><div><h3>Significance</h3><div>The incorporation of polyPS into calcium silicate-based cement may enhance apatite precipitation and accelerate the setting without altering the pH and solubility property.</div></div>","PeriodicalId":298,"journal":{"name":"Dental Materials","volume":"41 9","pages":"Pages 1058-1066"},"PeriodicalIF":4.6,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144339717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Crack propensity of different fiber-reinforced direct restorative procedures in deep MOD cavities","authors":"András Gábor Jakab ,&nbsp;Viktória Néma ,&nbsp;Janka Molnár ,&nbsp;Aliz Alföldi ,&nbsp;Gábor Braunitzer ,&nbsp;Dániel Palkovics ,&nbsp;Lippo Lassila ,&nbsp;Sufyan Garoushi ,&nbsp;Edina Lempel ,&nbsp;Márk Fráter","doi":"10.1016/j.dental.2025.06.010","DOIUrl":"10.1016/j.dental.2025.06.010","url":null,"abstract":"<div><h3>Objective</h3><div>The aim of this study was to evaluate crack formation associated with different direct restorative procedures at various time points.</div></div><div><h3>Methods</h3><div>This <em>in vitro</em> study included 100 intact third molars with standardized MOD cavities, divided into five groups (n = 20). After adhesive treatment, the cavities were restored as follows: bulk-fill flowable short fiber-reinforced composite (SFRC) (Group 1); conventional flowable resin composite (RC) base and bulk-fill flowable SFRC (Group 2); polyethylene fibers embedded in flowable RC and bulk-fill flowable SFRC (Group 3); flowable SFRC combined with packable SFRC (Group 4); and layered conventional packable RC (control). The presence and orientation (vertical/horizontal) of tooth cracks after restoration were evaluated using the D-light Pro (GC Europe) in “detection mode.” Cracks were examined at three distinct time points: immediately, after one week, and after five weeks of water storage. The Kruskal-Wallis and Dwass-Steel-Critchlow-Fligner tests were used for between- and within-group comparisons, respectively.</div></div><div><h3>Results</h3><div>No statistically significant difference in overall crack formation was observed between the groups immediately after the restorative procedure. At the one-week and five-week evaluations, the control group exhibited a significantly higher number of cracks compared to Groups 1–3 (p &lt; 0.01). All groups demonstrated a significantly higher number of cracks at the five-week evaluation compared to the immediate assessment (p &lt; 0.05). The SFRC groups predominantly showed horizontal cracks at all time points.</div></div><div><h3>Significance</h3><div>In the 5-week period of water storage following polymerization, the number of cracks appearing on the tooth gradually increased, but the flowable SFRC inserted using the bulk technique was able to moderate the phenomenon in MOD cavities.</div></div>","PeriodicalId":298,"journal":{"name":"Dental Materials","volume":"41 8","pages":"Pages 1034-1044"},"PeriodicalIF":4.6,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144315651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The next frontier in antibacterial dental resins: A 20-year journey of innovation and expectations","authors":"Mary Anne S. Melo ,&nbsp;Isadora Martini Garcia ,&nbsp;Tasneem Alluhaidan ,&nbsp;Masoumah Qaw ,&nbsp;Carolina Montoya ,&nbsp;Santiago Orrego ,&nbsp;Abdulrahman A. Balhaddad ,&nbsp;Lamia Mokeem","doi":"10.1016/j.dental.2025.06.013","DOIUrl":"10.1016/j.dental.2025.06.013","url":null,"abstract":"<div><h3>Objective</h3><div>Dental resin composites remain fundamental in restorative dentistry, but premature failures often compromise their long-term success Secondary caries, driven by acidogenic bacteria, salivary enzymes, and mechanical stresses. These failures frequently require complete restoration replacement, leading to increased costs and further loss of healthy tooth structure.</div></div><div><h3>Data</h3><div>This critical review examines two decades of relevant literature on innovation in antibacterial resin technologies, from early soluble additives (e.g., silver, fluoride, chlorhexidine) whose rapid leaching undermined mechanical performance to covalently bound quaternary ammonium monomers (QAMs) that provide durable, contact-active antimicrobial effects without significant filler loss. We further evaluate the integration of nanotechnology—metal-oxide nanoparticles, halloysite nanotubes, and graphene derivatives—to achieve sustained antimicrobial efficacy at low filler loadings, as well as emerging approaches using antimicrobial peptides, ionic liquids and piezoelectric fillers for environment-responsive action.</div></div><div><h3>Sources</h3><div>Peer-reviewed research articles and reviews were identified primarily via PubMed, Scopus, and Web of Science.</div></div><div><h3>Conclusion</h3><div>Early soluble additives effectively reduced bacteria, but they leached out too quickly, weakening the material. Quaternary ammonium compounds (QAMs) addressed this issue by offering long-lasting, surface-active antimicrobial properties. Nanofillers also provide sustained antimicrobial effects at low concentrations but face challenges such as particle clustering, potential toxicity, and uneven dispersion. New antimicrobial strategies like peptides, ionic liquids, and piezoelectric fillers show potential but face challenges such as biocompatibility, biofilm complexity, and limited real-world testing. Advancing these materials will require better preclinical models, cross-disciplinary collaboration, and computational tools to optimize antibacterial function and material strength.</div></div>","PeriodicalId":298,"journal":{"name":"Dental Materials","volume":"41 9","pages":"Pages 1045-1057"},"PeriodicalIF":4.6,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144315652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}