AME Case Reports最新文献

{"title":"Should bronchoscopic lavage after pulmonary aspiration be routinely offered?","authors":"Omar Lopez, Shreya Podder, Ajay Wagh","doi":"10.21037/acr-2026-0224","DOIUrl":"https://doi.org/10.21037/acr-2026-0224","url":null,"abstract":"","PeriodicalId":29752,"journal":{"name":"AME Case Reports","volume":"10 ","pages":"162"},"PeriodicalIF":0.6,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13659135/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149184353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum: Mitoxantrone liposome-based MEA regimen for treatment mixed lineage leukemia-rearranged acute myeloid leukemia: a case series.","authors":"","doi":"10.21037/acr-20262-03","DOIUrl":"https://doi.org/10.21037/acr-20262-03","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.21037/acr-25-19.].</p>","PeriodicalId":29752,"journal":{"name":"AME Case Reports","volume":"10 ","pages":"215"},"PeriodicalIF":0.6,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13659161/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149184390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Staged total arch repair for acute aortic dissection using physician-modified fenestrated thoracic endovascular aortic repair: a case report.","authors":"Atsutaka Aratame, Daisuke Kaku, Toshio Baba","doi":"10.21037/acr-2026-0216","DOIUrl":"https://doi.org/10.21037/acr-2026-0216","url":null,"abstract":"<p><strong>Background: </strong>Acute type A aortic dissection is a life-threatening condition requiring prompt surgical intervention. Although extensive repair, such as total arch replacement (TAR) with frozen elephant trunk (FET), may reduce late aortic events, this approach can be technically demanding and may increase procedural invasiveness and patient burden. A staged approach combining initial surgery with subsequent endovascular treatment may represent a practical alternative.</p><p><strong>Case description: </strong>We report a case of acute type A aortic dissection managed using a staged treatment strategy. Initial surgery was performed using transatrial left-ventricular (TALV) cannulation and partial aortic arch replacement with distal anastomosis in Ishimaru zone 2. This approach was selected to achieve rapid establishment of cardiopulmonary bypass and to avoid more extensive arch reconstruction during the emergency phase. After postoperative stabilisation and follow-up assessment of the residual dissection, physician-modified endograft (PMEG) fenestrated thoracic endovascular aortic repair (TEVAR) was performed as a second-stage procedure. The fenestration was tailored according to postoperative computed tomography (CT) findings, allowing the extension of treatment to the residual dissected arch and descending aorta while using the prosthetic graft as the proximal landing zone. This staged strategy may reduce the invasiveness of the initial lifesaving surgery while preserving the option for more complete aortic treatment after recovery.</p><p><strong>Conclusions: </strong>This case suggests that, in selected patients with acute type A aortic dissection, zone 2 aortic arch replacement followed by staged PMEG fenestrated TEVAR may be a feasible strategy. Careful postoperative assessment of residual dissection is essential to identify patients who may benefit from additional endovascular intervention.</p>","PeriodicalId":29752,"journal":{"name":"AME Case Reports","volume":"10 ","pages":"211"},"PeriodicalIF":0.6,"publicationDate":"2026-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13659147/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149184712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Primary malignant melanoma of the esophagus: a case report.","authors":"Yiru Wang, Xiaoting Chi, Jinglong Wang","doi":"10.21037/acr-2026-0118","DOIUrl":"https://doi.org/10.21037/acr-2026-0118","url":null,"abstract":"<p><strong>Background: </strong>Primary malignant melanoma of the esophagus (PMME) is an extremely rare malignant tumor with a poor prognosis. PMME accounts for 0.1% to 0.2% of all malignant esophageal tumors. Owing to its rarity and heterogeneity, there is currently a lack of standardized diagnostic and therapeutic guidelines, making clinical management challenging. Herein, we report this case to describe its clinicopathological features, treatment strategy, and clinical course.</p><p><strong>Case description: </strong>A 65-year-old Asian male patient presented with a two-month history of dysphagia. Upper gastrointestinal endoscopy revealed a large intraluminal mass in the middle to lower thoracic esophagus, and endoscopic biopsy suggested esophageal malignant melanoma. Postoperative histopathological and immunohistochemical examination confirmed malignant melanoma. Targeted physical evaluation of alternative potential primary sites and positron emission tomography/computed tomography (PET/CT) imaging revealed no additional primary lesions, supporting a primary esophageal origin. The patient underwent radical surgical resection followed by adjuvant chemotherapy, including nab-paclitaxel and carboplatin. At the final telephone follow-up approximately 28 months after surgery, no recurrence or distant metastasis was reported, and the patient maintained a good overall health status.</p><p><strong>Conclusions: </strong>This case describes a favorable clinical course following microscopically margin-negative resection and individualized adjuvant chemotherapy in a patient with localized PMME. However, the contribution of adjuvant chemotherapy to the outcome remains uncertain, and further studies are needed to establish optimal postoperative management.</p>","PeriodicalId":29752,"journal":{"name":"AME Case Reports","volume":"10 ","pages":"206"},"PeriodicalIF":0.6,"publicationDate":"2026-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13659170/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149184910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cat scratch disease with fever and lymphadenopathy without definite cat exposure diagnosed via tissue metagenomic next-generation sequencing technology: a case report.","authors":"Shuang Yang, Minghui Zhu, Zhenshun Cheng","doi":"10.21037/acr-2026-0079","DOIUrl":"https://doi.org/10.21037/acr-2026-0079","url":null,"abstract":"<p><strong>Background: </strong>Cat scratch disease (CSD), a disease caused by <i>Bartonella henselae</i> (<i>B. henselae</i>), is often associated with exposure to cats. However, in rare cases, a history of cat exposure is absent, and thus achieving a definitive diagnosis may be challenging. Metagenomic next-generation sequencing (mNGS) is a relatively new technology that can analyze pathogens without introducing inherent biases. In this report, we describe a case of CSD diagnosed via mNGS, which supports the use of mNGS in identifying rare types of pathogenic infection.</p><p><strong>Case description: </strong>A 54-year-old male exhibited fever and headache of unknown cause, with a history of working at a chicken farm and no clear cat exposure. Routine antibiotic treatment for infection was ineffective. Lymph node biopsy demonstrated granulomas accompanied by chronic suppurative inflammation and abscess formation. A biopsy sample from the parotid lymph node was subjected to mNGS, which revealed the presence of <i>B. henselae</i> and led to a subsequent diagnosis of CSD. After treatment with azithromycin, the patient recovered and was discharged. At the 3-month telephone follow-up, the patient was asymptomatic.</p><p><strong>Conclusions: </strong>CSD in patients with prolonged fever plus culture-negative granulomatous lymphadenopathy or similar compatible findings, even when the exposure history is atypical，and mNGS, as an effective examination method, can aid in arriving at a definitive diagnosis.</p>","PeriodicalId":29752,"journal":{"name":"AME Case Reports","volume":"10 ","pages":"210"},"PeriodicalIF":0.6,"publicationDate":"2026-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13659113/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149184818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Compound heterozygous <i>RSPH4A</i> variants associated with suspected primary ciliary dyskinesia in a Chinese family: a case report and literature review.","authors":"Jiali Huang, Fei Tong, Kaiyue Xiao, Xinyu Zhai, Xuyang Zheng","doi":"10.21037/acr-2026-0172","DOIUrl":"https://doi.org/10.21037/acr-2026-0172","url":null,"abstract":"<p><strong>Background: </strong>Primary ciliary dyskinesia (PCD) is a genetically heterogeneous disorder caused by defects in ciliary structure and function, leading to impaired mucociliary clearance and chronic respiratory tract infections. The radial spoke head protein 4 homolog A (<i>RSPH4A</i>) gene is one of over 50 genes responsible for causing PCD. The diagnosis of PCD is challenging because symptoms are nonspecific and overlap with common respiratory diseases, such as asthma and recurrent bronchitis, while definitive diagnosis requires specialized and not widely available techniques, such as transmission electron microscopy (TEM) and genetic testing, with test results being not always positive.</p><p><strong>Case description: </strong>The female proband, of 11-year-old, presented chronic cough, recurrent pneumonia, bronchiectasis. Her nasal nitric oxide (nNO) level was 5 ppb, which is markedly below the age-specific reference threshold of 113 ppb for an 11-year-old child. Genetic testing revealed two novel compound heterozygous variants in the <i>RSPH4A</i> gene: a nonsense variant c.658A>T (p.Lys220Ter) and a synonymous variant c.1764G>T (p.Gly588=), both of which were confirmed by Sanger sequencing. Family segregation analysis demonstrated that the proband inherited the two variants from her asymptomatic father and mother, respectively, confirming compound heterozygosity. Although cough symptoms improved following treatment with antibiotics, bronchoscopy secretions aspiration, and inhaled corticosteroids, the follow-up at 3 months revealed persistent moderate obstructive ventilatory dysfunction with no significant improvement.</p><p><strong>Conclusions: </strong>This case expands the mutational spectrum of <i>RSPH4A</i>-associated PCD and highlights that synonymous variants should not be routinely excluded from pathogenicity assessment in patients with a compatible PCD phenotype.</p>","PeriodicalId":29752,"journal":{"name":"AME Case Reports","volume":"10 ","pages":"209"},"PeriodicalIF":0.6,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13659174/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149183984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bone marrow necrosis and rapidly progressive liver metastases after breast-conserving surgery in a 33-year-old woman with triple-negative breast cancer, followed by death 288 days after surgery: a case report.","authors":"Hongmei Wang, Jinyue Gao, Shouman Wang","doi":"10.21037/acr-2026-0134","DOIUrl":"https://doi.org/10.21037/acr-2026-0134","url":null,"abstract":"<p><strong>Background: </strong>Bone marrow necrosis (BMN) is rare, and malignancy-associated BMN often reflects high tumor burden, rapid progression, and poor prognosis. BMN after definitive treatment for early triple-negative breast cancer (TNBC), followed by visceral progression and coagulation-fibrinolytic abnormalities, is rarely reported.</p><p><strong>Case description: </strong>A 33-year-old woman underwent breast-conserving surgery and sentinel lymph node biopsy for a 1.8 cm grade 3 invasive carcinoma of no special type. One of four sentinel nodes was positive (pT1cN1a, cM0); the surgical specimen was estrogen receptor (ER)-negative, progesterone receptor (PR)-negative, human epidermal growth factor receptor 2 (HER2) 0, with Ki-67 approximately 90%, consistent with TNBC. She completed four cycles of epirubicin plus cyclophosphamide followed by four cycles of liposomal paclitaxel and adjuvant radiotherapy. Six days after radiotherapy, recurrent fever, bone pain, and progressive thrombocytopenia developed, followed by pancytopenia. Bone marrow biopsy on October 23, 2025 showed extensive necrosis with only a few degenerating nucleated cells and no clearly identifiable viable malignant cells. Contrast-enhanced computed tomography (CT) on November 21 showed liver metastases. On November 25, white blood cell count (WBC) was 1.9×10⁹/L, hemoglobin 54.0 g/L, platelets 4×10⁹/L, aspartate aminotransferase (AST) 308.9 U/L, total bilirubin 60.8 μmol/L, and lactate dehydrogenase (LDH) 2758.1 U/L. D-dimer was 19.49 mg/L, approximately 39 times the laboratory upper reference limit of 0.5 mg/L; prothrombin time (PT) was 15.3 s, below the documented upper reference limit of 21 s; and fibrinogen was 2.11 g/L. Retrospective application of the 2025 International Society on Thrombosis and Haemostasis (ISTH) overt disseminated intravascular coagulation (DIC) score yielded 5 points, meeting the scoring threshold. D-dimer later exceeded 40.00 mg/L, activated partial thromboplastin time (APTT) and thrombin time increased, and fibrinogen fell to 1.11 g/L. Hepatic and renal dysfunction and multiorgan failure ensued, and she died on December 2, 2025, 288 days after surgery.</p><p><strong>Conclusions: </strong>In aggressive breast cancer, persistent fever, progressive bone pain, rapidly falling blood counts, and elevated LDH should prompt early evaluation for BMN and possible marrow involvement, with assessment for infection, coagulation disorders, hemophagocytic syndrome, and systemic progression. Marked thrombocytopenia with striking D-dimer elevation warrants dynamic DIC assessment even when PT remains within the local reference range. The temporal relationships among BMN, DIC, and prior therapy should be interpreted cautiously.</p>","PeriodicalId":29752,"journal":{"name":"AME Case Reports","volume":"10 ","pages":"208"},"PeriodicalIF":0.6,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13659176/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149184794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"¹⁸F-AlF-NOTA-FAPI-04 PET/CT as a complementary tool for detecting occult signet-ring cell gastric adenocarcinoma when FDG imaging is inconclusive: a case report.","authors":"Cheng Yuan, Mingzhe Lai, Yanzhi Fu, Peng Wang, Meini Pan, Rui Bai, Wenli Dai, Eyi Ben, Lu Xu, Xiang Dong, Tingzhuang Yi, Lihua Ni","doi":"10.21037/acr-2026-0158","DOIUrl":"https://doi.org/10.21037/acr-2026-0158","url":null,"abstract":"<p><strong>Background: </strong>Accurate identification of the primary site in metastatic cancer remains a significant challenge when conventional imaging, such as fluorine-18 fluorodeoxyglucose (¹⁸F-FDG) positron emission tomography/computed tomography (PET/CT), yields inconclusive results. This issue is particularly evident in stroma-rich tumors, such as signet-ring cell carcinoma, which exhibit low glycolytic activity and are characterized by an abundance of cancer-associated fibroblasts (CAFs). ¹⁸F-AlF-NOTA-FAPI-04 PET/CT, which targets fibroblast activation protein (FAP), offers a promising alternative by providing detailed imaging of the tumor microenvironment (TME).</p><p><strong>Case description: </strong>A 34-year-old male presented with altered bowel habits and right inguinal lymphadenopathy. Histology of the lymph node revealed metastatic poorly differentiated carcinoma, suggesting gastrointestinal origin. However, abdominal CT and ¹⁸F-FDG PET/CT failed to identify the primary lesion, showing only mild gastric wall thickening with weak FDG uptake. One week later, fluorine-18 fibroblast activator protein inhibitor (¹⁸F-FAPI) PET/CT revealed significantly increased uptake in the gastric fundus and body, and a hypermetabolic lesion in the right iliopsoas muscle. Guided by these findings, targeted biopsies confirmed poorly differentiated gastric adenocarcinoma with signet-ring cell features. After eight cycles of capecitabine plus oxaliplatin (XELOX) chemotherapy over a 6-month period, follow-up ¹⁸F-FAPI PET/CT showed marked tumor regression.</p><p><strong>Conclusions: </strong>¹⁸F-FAPI PET/CT can provide complementary biological and diagnostic information when ¹⁸F-FDG imaging is inconclusive, particularly in stroma‑rich gastric cancers with signet‑ring cell features. In this patient, FAPI PET/CT enabled targeted biopsy and demonstrated treatment response, suggesting its potential value in clinical management. Larger prospective studies are warranted to further define the role of ¹⁸F-FAPI PET/CT in the diagnostic algorithm of occult primary tumors.</p>","PeriodicalId":29752,"journal":{"name":"AME Case Reports","volume":"10 ","pages":"207"},"PeriodicalIF":0.6,"publicationDate":"2026-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13659166/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149184772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Late-onset bilateral pulmonary vein stenosis after living-donor lobar lung transplantation managed with balloon angioplasty: a case report.","authors":"Daisuke Taniguchi, Yuki Ueno, Takuro Miyazaki, Ryoichiro Doi, Koichiro Shimoyama, Tomohiro Obata, Satoshi Mizoguchi, Ryosuke Ogata, Yoshimitsu Soga, Koji Maemura, Keitaro Matsumoto","doi":"10.21037/acr-2026-0177","DOIUrl":"https://doi.org/10.21037/acr-2026-0177","url":null,"abstract":"<p><strong>Background: </strong>Pulmonary vein stenosis (PVS) is a rare but potentially life-threatening complication after lung transplantation. Most reported cases occur during the early postoperative period and are associated with technical issues at the venous anastomosis. Late-onset PVS is extremely uncommon and may be overlooked because its clinical presentation mimics infection, rejection, or chronic lung allograft dysfunction (CLAD).</p><p><strong>Case description: </strong>A woman in her 20s with familial interstitial pneumonia underwent living-donor lobar lung transplantation (LDLLT). Her postoperative course was uneventful, and graft function remained stable for 2 years. She subsequently developed progressive dyspnea, hypoxemia, and massive pleural effusion. Computed tomography (CT) angiography demonstrated bilateral PVS at the venous anastomotic sites. Right heart catheterization revealed significant diastolic pressure gradients between pulmonary artery wedge pressure and left atrial pressure, confirming physiologically significant PVS. Transseptal balloon angioplasty was successfully performed for both pulmonary veins. Mean pulmonary arterial pressure decreased immediately from 66 to 35 mmHg, and pulmonary vein flow velocities on Doppler echocardiography improved substantially. Follow-up catheterization demonstrated near-complete resolution of the pressure gradients. The patient recovered rapidly and remained asymptomatic without restenosis at 12-month follow-up.</p><p><strong>Conclusions: </strong>Late-onset bilateral PVS after LDLLT is extremely rare but may result in severe cardiopulmonary deterioration. Because the clinical manifestations are nonspecific, delayed diagnosis may occur. Balloon angioplasty may provide favorable short-term clinical and hemodynamic improvement in selected patients.</p>","PeriodicalId":29752,"journal":{"name":"AME Case Reports","volume":"10 ","pages":"205"},"PeriodicalIF":0.6,"publicationDate":"2026-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13659131/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149184791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Symptomatic intrahepatic subcapsular hematoma-derived liver cyst following laparoscopic cholecystectomy: a case report.","authors":"Kyohei Abe, Shuichi Fujioka, Yuki Takano, Yoshihiro Shirai, Koichiro Haruki, Kenei Furukawa, Michinori Matsumoto, Masashi Tsunematsu, Ryoga Hamura, Toru Ikegami","doi":"10.21037/acr-2026-0157","DOIUrl":"https://doi.org/10.21037/acr-2026-0157","url":null,"abstract":"<p><strong>Background: </strong>Intrahepatic subcapsular hematoma (ISH) is a rare complication following laparoscopic cholecystectomy (LC). Although most reported cases occur in the early postoperative period and resolve with conservative treatment, the management of chronic or refractory ISH remains unclear. We report a delayed, symptomatic cystic lesion that developed from postoperative ISH and was treated laparoscopically.</p><p><strong>Case description: </strong>A 70-year-old man receiving aspirin for a previous myocardial infarction underwent LC for cholelithiasis and cholecystitis. Aspirin was resumed on postoperative day (POD) 2. On POD 4, decreased hemoglobin and elevated C-reactive protein levels prompted computed tomography, which revealed an ISH extending from the gallbladder bed to the right hepatic lobe. The patient was initially managed conservatively. On POD 105, a hepatic cystic lesion approximately 15 cm in diameter was detected, without laboratory evidence of inflammation. On POD 380, worsening abdominal pain and elevated inflammatory markers suggested secondary infection. Percutaneous drainage on POD 385 produced only temporary improvement, and the lesion recurred. Laparoscopic fenestration was therefore performed on POD 510. Indocyanine green fluorescence imaging clearly distinguished the non-fluorescent cyst wall from the surrounding hepatic parenchyma and facilitated safe resection. The postoperative course was uneventful, and no recurrence was observed during 1 year of follow-up.</p><p><strong>Conclusions: </strong>ISH following LC may evolve over several months into a chronic cystic lesion and subsequently become infected. Long-term follow-up should be considered for persistent or enlarging ISH. When conservative management and percutaneous drainage fail, laparoscopic fenestration with indocyanine green fluorescence imaging may provide a safe and definitive treatment option.</p>","PeriodicalId":29752,"journal":{"name":"AME Case Reports","volume":"10 ","pages":"203"},"PeriodicalIF":0.6,"publicationDate":"2026-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13659150/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149184669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}