International Journal of Cardiology Cardiovascular Risk and Prevention最新文献

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Regional and demographic variations in diabetes mellitus and myocardial infarction mortality among US adults: A retrospective observational analysis from 1999 to 2023 美国成人糖尿病和心肌梗死死亡率的地区和人口统计学差异:1999年至2023年的回顾性观察分析
IF 1.9
International Journal of Cardiology Cardiovascular Risk and Prevention Pub Date : 2025-06-18 DOI: 10.1016/j.ijcrp.2025.200456
Ahlam Safdar Hussain , Sumantra Kumar De , Griff Chatwin , Maryam Shahzad , Eeshal Zulfiqar , Vaisnavy Govindasamy , Megha Goel , Muhammad Muneeb Arshad , Mohib Naseer , Syed Rizwan Bokhari , Muhammad Atif Rauf , Sundas Hasan , Mushood Ahmed , Raheel Ahmed
{"title":"Regional and demographic variations in diabetes mellitus and myocardial infarction mortality among US adults: A retrospective observational analysis from 1999 to 2023","authors":"Ahlam Safdar Hussain ,&nbsp;Sumantra Kumar De ,&nbsp;Griff Chatwin ,&nbsp;Maryam Shahzad ,&nbsp;Eeshal Zulfiqar ,&nbsp;Vaisnavy Govindasamy ,&nbsp;Megha Goel ,&nbsp;Muhammad Muneeb Arshad ,&nbsp;Mohib Naseer ,&nbsp;Syed Rizwan Bokhari ,&nbsp;Muhammad Atif Rauf ,&nbsp;Sundas Hasan ,&nbsp;Mushood Ahmed ,&nbsp;Raheel Ahmed","doi":"10.1016/j.ijcrp.2025.200456","DOIUrl":"10.1016/j.ijcrp.2025.200456","url":null,"abstract":"<div><h3>Background</h3><div>Individuals with diabetes mellitus (DM) are at an increased risk of having myocardial infarction (MI). We aim to identify the trends in the mortality rates from DM and MI among US adults stratified by demographic and geographical parameters.</div></div><div><h3>Methods</h3><div>The CDC-WONDER database was used to extract death certificate data for adults aged ≥25 years. Crude mortality rates (CMR) and age-adjusted mortality rates (AAMRs) per 100,000 persons were calculated, and temporal trends were identified by calculating annual percent change (APC) using JoinPoint regression analysis.</div></div><div><h3>Results</h3><div>From 1999 to 2023, a total of 712,921 DM and MI-related deaths were reported among adults in the United States. The AAMR significantly declined from 18.99 in 1999 to 10.20 in 2018 Following this, the AAMR rose to 12.27 in 2021, with an APC of 7.2 (95 % CI: 4.7 to 8.9). This was followed by a decline in AAMR to the pre-pandemic levels (AAMR: 9.6 in 2023). The AAMR for males was considerably higher compared to women throughout the study period (16.5 vs. 10.2). Non-Hispanic Black or African American people had the highest AAMR (19.5), followed by Hispanic or Latino people (15.3), NH white people (12.5), and NH other populations (11.2). Southern region and rural areas experienced higher mortality rates compared to urban areas.</div></div><div><h3>Conclusion</h3><div>We observed decreasing trends in DM and myocardial infarction-related deaths throughout the study period, however, a surge was noted during the COVID-19 pandemic. Mortality is higher among men, NH black populations, and rural areas.</div></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"26 ","pages":"Article 200456"},"PeriodicalIF":1.9,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144331279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The association between sugars sweetened beverages and glycemic profile among children and youth: A systematic review and dose-response meta-analysis 含糖饮料与儿童和青少年血糖状况之间的关系:一项系统综述和剂量反应荟萃分析
IF 1.9
International Journal of Cardiology Cardiovascular Risk and Prevention Pub Date : 2025-06-14 DOI: 10.1016/j.ijcrp.2025.200453
Mahdieh Abbasalizad Farhangi , Zeinab Nikniaz , Seyedeh-Tarlan Mirzohreh , Leila Nikniaz
{"title":"The association between sugars sweetened beverages and glycemic profile among children and youth: A systematic review and dose-response meta-analysis","authors":"Mahdieh Abbasalizad Farhangi ,&nbsp;Zeinab Nikniaz ,&nbsp;Seyedeh-Tarlan Mirzohreh ,&nbsp;Leila Nikniaz","doi":"10.1016/j.ijcrp.2025.200453","DOIUrl":"10.1016/j.ijcrp.2025.200453","url":null,"abstract":"<div><h3>Background</h3><div>This study aimed to assess the effects of Sugar-Sweetened Beverages (SSBs) consumption on fasting serum insulin (FSI), fasting plasma glucose (FPG), and HOMA-IR levels among children.</div></div><div><h3>Methods</h3><div>Databases including PubMed/MEDLINE, Scopus, EMBASE, Cochrane Library, and Web of Science were searched up to March 2025. Observational studies reporting the connection of SSBs consumption with FPG, FSI, and HOMA-IR levels were included. STATA version 15 was used to analyze the data.</div></div><div><h3>Results</h3><div>11 studies with 22,713 subjects were included in this meta-analysis. Greater intake of SSBs was not significantly linked to higher fasting plasma glucose (WMD: 0.01; CI -0.04 –0.07; P = 0.63) and fasting serum insulin levels (WMD: 0.54; 95 % CI, −0.4, 1.49; P = 0.26). However, high SSBs consumption was significantly associated with a 0.21 increase in HOMA-IR in adolescents and children (WMD: 0.21; CI, 0.03–0.37; P = 0.02). In dose-response meta-analysis, no departure from linearity was detected between SSBs intake and changes in FPG, FSI, and HOMA-IR levels.</div></div><div><h3>Conclusions</h3><div>High SSBs intake was linked to increased HOMA-IR levels among adolescents and children. Further extensive prospective long-term interventions are suggested to confirm the detected associations.</div></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"26 ","pages":"Article 200453"},"PeriodicalIF":1.9,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144470155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Harnessing artificial intelligence for early prediction of cardiogenic shock and mortality in acute coronary syndrome patients 利用人工智能早期预测急性冠脉综合征患者的心源性休克和死亡率
IF 1.9
International Journal of Cardiology Cardiovascular Risk and Prevention Pub Date : 2025-06-12 DOI: 10.1016/j.ijcrp.2025.200448
John Patrick C. Toledo
{"title":"Harnessing artificial intelligence for early prediction of cardiogenic shock and mortality in acute coronary syndrome patients","authors":"John Patrick C. Toledo","doi":"10.1016/j.ijcrp.2025.200448","DOIUrl":"10.1016/j.ijcrp.2025.200448","url":null,"abstract":"","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"26 ","pages":"Article 200448"},"PeriodicalIF":1.9,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144335737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Walking as a viable alternative to moderate-to-vigorous physical activity for improving cardiovascular outcomes in coronary artery disease patients 步行作为一种可行的替代中度至剧烈体育活动,可改善冠心病患者的心血管预后
IF 1.9
International Journal of Cardiology Cardiovascular Risk and Prevention Pub Date : 2025-06-09 DOI: 10.1016/j.ijcrp.2025.200452
Zejun Yang , Yunting Liang , Liu He , Le Zhou , Xiaodong Peng , Yiwei Lai , Cong Yuan , Xiaoxia Liu , Ning Zhou , Weihua Zhang , Caihua Sang , Qian Tong , Xin Du , Jianzeng Dong , Changsheng Ma
{"title":"Walking as a viable alternative to moderate-to-vigorous physical activity for improving cardiovascular outcomes in coronary artery disease patients","authors":"Zejun Yang ,&nbsp;Yunting Liang ,&nbsp;Liu He ,&nbsp;Le Zhou ,&nbsp;Xiaodong Peng ,&nbsp;Yiwei Lai ,&nbsp;Cong Yuan ,&nbsp;Xiaoxia Liu ,&nbsp;Ning Zhou ,&nbsp;Weihua Zhang ,&nbsp;Caihua Sang ,&nbsp;Qian Tong ,&nbsp;Xin Du ,&nbsp;Jianzeng Dong ,&nbsp;Changsheng Ma","doi":"10.1016/j.ijcrp.2025.200452","DOIUrl":"10.1016/j.ijcrp.2025.200452","url":null,"abstract":"<div><h3>Background</h3><div>Home-based cardiac rehabilitation is recommended for coronary artery disease (CAD) patients, while exercise is the most important component. There is lack of evidence on whether walking alone can improve cardiovascular prognosis in CAD patients, particularly those unable to tolerate moderate-to-vigorous physical activity (MVPA).</div></div><div><h3>Methods</h3><div>Participants with diagnosed CAD from the UK Biobank with baseline PA assessment were included. PA data, including total PA, MVPA, and walking, were collected using the International Physical Activity Questionnaire, and expressed as the total metabolic equivalent of tasks minutes per week. We accessed the association between PA and cardiovascular composite outcome (cardiac death, heart failure hospitalization, non-fatal myocardial infarction, percutaneous coronary intervention, coronary artery bypass grafting) and all-cause mortality.</div></div><div><h3>Result</h3><div>Over a median follow-up of 13.5 years, incidence of all-cause mortality (21.6, 16.7, 15.9, 15.6 per 1000 person-years) and cardiovascular composite events (20.6, 17.8, 17.8, 17.2 per 1000 person-years) decreased with increasing time of total PA in 19,074 patients. Notably, for patients who did not meet AHA/ESC/WHO recommendations, achieving an adequate amount of walking (100 min/week) reduced risk of cardiovascular composite outcome (HR = 0.84, 95 %CI [0.71–0.99], p = 0.038) and all-cause mortality (HR = 0.84, 95 %CI [0.77–0.91], p &lt; 0.001). In patients with lower levels of PA, replacing 30 min per day of sedentary behavior with walking or MVPA reduced all-cause mortality risk.</div></div><div><h3>Conclusion</h3><div>In this large cohort, prolonged exercise duration, including total PA, MVPA and walking, may reduce the cardiovascular risks for CAD patients. For patients unable to tolerate MVPA, walking may serve as a suitable alternative.</div></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"26 ","pages":"Article 200452"},"PeriodicalIF":1.9,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144364834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between cardiac rehabilitation and LDL-levels, adherence to guideline-recommended medication and mortality rate after myocardial infarction 心脏康复与ldl水平、指南推荐药物依从性和心肌梗死后死亡率之间的关系
IF 1.9
International Journal of Cardiology Cardiovascular Risk and Prevention Pub Date : 2025-06-07 DOI: 10.1016/j.ijcrp.2025.200444
Ahmad Agam , David Vadsholt , Kristian Kragholm , Lauge Klement Moltke Østergaard , Peter Bisgaard Stæhr , Gitte Nielsen , Henrik Vadmann
{"title":"Association between cardiac rehabilitation and LDL-levels, adherence to guideline-recommended medication and mortality rate after myocardial infarction","authors":"Ahmad Agam ,&nbsp;David Vadsholt ,&nbsp;Kristian Kragholm ,&nbsp;Lauge Klement Moltke Østergaard ,&nbsp;Peter Bisgaard Stæhr ,&nbsp;Gitte Nielsen ,&nbsp;Henrik Vadmann","doi":"10.1016/j.ijcrp.2025.200444","DOIUrl":"10.1016/j.ijcrp.2025.200444","url":null,"abstract":"<div><h3>Aim</h3><div>This study aims to identify three-month and one year mortality rate, LDL level and adherence to guideline-recommended medication in patients with myocardial infarct (MI) receiving cardiac rehabilitation (CR) compared to patients who do not.</div></div><div><h3>Method</h3><div>In this retrospective study, patients hospitalized in North Denmark Regional Hospital in Hjoerring (capture population 200.000) with acute coronary syndrome between January 1st, 2017, to December 31st, 2021, were included. Baseline characteristics, initial treatment of revascularization and all-cause mortality were examined through the Danish National Patient Registry, the Regional Cardiac Rehabilitation Database, and medical chart review. Patients were grouped by revascularization (yes/no) during hospitalization and CR. Adjusted Cox proportional regression model was used to assess differences in mortality and LDL levels.</div></div><div><h3>Results</h3><div>A total of 1209 myocardial infarction (MI) survivors were included in this study. A total of 1209 myocardial infarction (MI) survivors were included. Significant LDL reductions at 6- and 12-month follow-ups were observed in patients receiving both cardiac rehabilitation (CR) and lipid-modifying therapy at baseline (p = .001), but not in those without CR. In revascularized patients, use of multiple antithrombotic agents was lower in the no CR group at three months (57.1 % vs 78.8 %, p = .002) and one year (60 % vs 78.5 %, p = .010). Three-month mortality rate was higher among patients who did not undergo CR, both in the revascularization group (19 % vs 2 %, p = 0.001) and the non-revascularization group (18 % vs 3 %, p = 0.001).</div></div><div><h3>Conclusion</h3><div>Patients undergoing CR were associated with lower LDL-levels, higher adherence to guideline-recommended medication and lower mortality rate at three-month follow-up.</div></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"26 ","pages":"Article 200444"},"PeriodicalIF":1.9,"publicationDate":"2025-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144253577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From popularity to peril? Evaluating cardiovascular risks of low-carbohydrate high-fat diets across diverse populations 从受欢迎走向危险?评估不同人群低碳水化合物高脂肪饮食的心血管风险
IF 1.9
International Journal of Cardiology Cardiovascular Risk and Prevention Pub Date : 2025-06-06 DOI: 10.1016/j.ijcrp.2025.200447
Jose Eric M. Lacsa
{"title":"From popularity to peril? Evaluating cardiovascular risks of low-carbohydrate high-fat diets across diverse populations","authors":"Jose Eric M. Lacsa","doi":"10.1016/j.ijcrp.2025.200447","DOIUrl":"10.1016/j.ijcrp.2025.200447","url":null,"abstract":"","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"26 ","pages":"Article 200447"},"PeriodicalIF":1.9,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144239571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Addressing the gaps in pregnancy-related cardiovascular risk assessment 消除妊娠相关心血管风险评估中的差距
IF 1.9
International Journal of Cardiology Cardiovascular Risk and Prevention Pub Date : 2025-06-06 DOI: 10.1016/j.ijcrp.2025.200446
Javeria Akhter , Javed Iqbal
{"title":"Addressing the gaps in pregnancy-related cardiovascular risk assessment","authors":"Javeria Akhter ,&nbsp;Javed Iqbal","doi":"10.1016/j.ijcrp.2025.200446","DOIUrl":"10.1016/j.ijcrp.2025.200446","url":null,"abstract":"","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"26 ","pages":"Article 200446"},"PeriodicalIF":1.9,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144239570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of a mHealth intervention on health literacy in patients completing cardiac rehabilitation: A randomized controlled trial with one- and five-year follow-up 移动健康干预对完成心脏康复患者健康素养的影响:一项1年和5年随访的随机对照试验
IF 1.9
International Journal of Cardiology Cardiovascular Risk and Prevention Pub Date : 2025-06-06 DOI: 10.1016/j.ijcrp.2025.200445
Pernille Lunde , Hanne Søberg Finbråten , Are Hugo Pripp , Birgitta Blakstad Nilsson , Jostein Grimsmo , Asta Bye
{"title":"Effect of a mHealth intervention on health literacy in patients completing cardiac rehabilitation: A randomized controlled trial with one- and five-year follow-up","authors":"Pernille Lunde ,&nbsp;Hanne Søberg Finbråten ,&nbsp;Are Hugo Pripp ,&nbsp;Birgitta Blakstad Nilsson ,&nbsp;Jostein Grimsmo ,&nbsp;Asta Bye","doi":"10.1016/j.ijcrp.2025.200445","DOIUrl":"10.1016/j.ijcrp.2025.200445","url":null,"abstract":"<div><h3>Background and aims</h3><div>Adherence to treatment is a significant challenge for patients with cardiac disease. Optimizing health literacy (HL) is essential in this context. Mobile health (mHealth) interventions have been suggested to improve both treatment adherence and HL. This study aimed to examine the effect of a one-year mHealth intervention on HL and to compare HL changes between the intervention- and the control group.</div></div><div><h3>Methods</h3><div>This randomized controlled trial included patients completing cardiac rehabilitation, who were randomly allocated to either an intervention group receiving individualized follow-up via an app for one year or a control group receiving usual care. From one-year follow-up to the five-year follow-up, both groups received usual care. HL was measured using the HLS-Q12. Mixed model for repeated measurements and Wilcoxon signed rank test were used to analyse differences between groups, while paired sample <em>t</em>-test and Kendall's Tau b correlation analysed within-group changes.</div></div><div><h3>Results</h3><div>A total of 113 patients were included in the study. No statistically significant differences between the groups were found in total HLS-Q12 score or at item level at any follow-up. However, a statistically significant within-group improvement was observed in the intervention group for the total score (mean change of 2.5 ± 4.6, p &lt; 0.01) and several HLS-Q12 items from baseline to one-year follow-up.</div></div><div><h3>Conclusions</h3><div>The one-year mHealth intervention did not show an effect on HL levels at one- or five-year follow-ups. However, significant within-group HL improvement from baseline to one-year follow-up suggests that mHealth interventions may have the potential to enhance HL.</div></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"26 ","pages":"Article 200445"},"PeriodicalIF":1.9,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144239567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between asthma and cardiovascular disease among a United States representative population 美国代表性人群中哮喘与心血管疾病的关系
IF 1.9
International Journal of Cardiology Cardiovascular Risk and Prevention Pub Date : 2025-06-06 DOI: 10.1016/j.ijcrp.2025.200451
Humza Naqvi , Charles D. Searles
{"title":"Association between asthma and cardiovascular disease among a United States representative population","authors":"Humza Naqvi ,&nbsp;Charles D. Searles","doi":"10.1016/j.ijcrp.2025.200451","DOIUrl":"10.1016/j.ijcrp.2025.200451","url":null,"abstract":"","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"26 ","pages":"Article 200451"},"PeriodicalIF":1.9,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144239568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The hidden burden: Inflammatory bowel disease and cardiovascular mortality in underreported populations 隐藏的负担:未报告人群中的炎症性肠病和心血管死亡率
IF 1.9
International Journal of Cardiology Cardiovascular Risk and Prevention Pub Date : 2025-06-06 DOI: 10.1016/j.ijcrp.2025.200449
Jose Eric M. Lacsa
{"title":"The hidden burden: Inflammatory bowel disease and cardiovascular mortality in underreported populations","authors":"Jose Eric M. Lacsa","doi":"10.1016/j.ijcrp.2025.200449","DOIUrl":"10.1016/j.ijcrp.2025.200449","url":null,"abstract":"<div><div>Recent data from the United States reveal a rising trend in mortality linked to inflammatory bowel disease (IBD) and cardiovascular disease (CVD), with pronounced disparities across age, sex, race, and geography. This commentary reappropriates those findings within the context of the Philippines and other low- and middle-income countries (LMICs), where chronic inflammation remains underdiagnosed and health systems are ill-equipped to address its cardiovascular consequences. While CVD is already the leading cause of death in the Philippines, the compounding effects of inflammatory disorders like IBD are largely overlooked. Drawing parallels from U.S. patterns, we highlight how rural-urban divides, healthcare inaccessibility, and poor disease surveillance may fuel similar trends in LMICs. We call for integrated screening strategies, improved chronic disease registries, and cross-disciplinary approaches that recognize inflammation as a key driver of cardiovascular risk. The global burden of cardiovascular disease cannot be fully addressed without confronting the silent role of systemic inflammation.</div></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"26 ","pages":"Article 200449"},"PeriodicalIF":1.9,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144262772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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