International Journal of Cardiology Cardiovascular Risk and Prevention最新文献

{"title":"Analysis of the association between long-term exposure to low-dose ionizing radiation and dyslipidemia and its components in medical radiologists: The mediating role of inflammatory markers","authors":"Changyong Wen ,&nbsp;Xiaolian Liu ,&nbsp;Yiqing Lian ,&nbsp;Weizhen Guo ,&nbsp;Lingyu Zhang ,&nbsp;Yanting Chen ,&nbsp;Xin Lan ,&nbsp;Mingfang Li ,&nbsp;Sufen Zhang ,&nbsp;Weixu Huang ,&nbsp;Jianming Zou ,&nbsp;Huifeng Chen","doi":"10.1016/j.ijcrp.2025.200406","DOIUrl":"10.1016/j.ijcrp.2025.200406","url":null,"abstract":"<div><h3>Introduction</h3><div>Our study aimed to explore the association between long-term exposure to low-dose ionizing radiation (LDIR) and dyslipidemia and its components among medical radiologists, and to identify the mediating role of inflammatory markers.</div></div><div><h3>Methods</h3><div>This cross-sectional study was conducted on 3918 medical radiologists, with data collected through questionnaires and occupational external exposure dosimeters. The multifactorial logistic regression and restricted cubic spline model were used to analyze the association between long-term exposure to LDIR and dyslipidemia and its components among medical radiologists, and mediation analysis was used to identify potential mediation effects.</div></div><div><h3>Results</h3><div>Of 3918 medical radiologists, 995 (25.4 %) had dyslipidemia. The gender, age, body mass index (BMI), and smoking status were influential factors for dyslipidemia of medical radiologists. After adjusting for confounders, the OR and 95 % CI for the occurrence of dyslipidemia and high TG in the highest tertile group (Q3) were 1.32 (95 % CI: 1.04, 1.67) and 1.51 (95 % CI: 1.11, 2.07), respectively. Restricted cubic spline model showed that the cumulative effective dose was linearly associated with both dyslipidemia and high TG, and the risk of dyslipidemia and high TG increased with the cumulative effective dose. Mediation analysis suggested that the inflammatory marker SII significantly mediated the association between cumulative effective dose and TG levels.</div></div><div><h3>Conclusion</h3><div>Our study shows that medical radiologists have a high detection rate of dyslipidemia, and the risk of dyslipidemia and high TG increases with increasing cumulative effective dose. Inflammatory marker SII may play a mediating role in the association between cumulative effective dose and TG levels.</div></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"25 ","pages":"Article 200406"},"PeriodicalIF":1.9,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143848202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hyperuricemia and adverse outcomes in patients with cardiorenal syndrome: A nationwide prospective cohort study in China","authors":"Zhanyuan Chen ,&nbsp;Yaoyao Wang ,&nbsp;Lili Liu ,&nbsp;Xuejiao Liu ,&nbsp;Rui Zhu ,&nbsp;Yu Wei ,&nbsp;Lihua Zhang ,&nbsp;Jianfang Cai","doi":"10.1016/j.ijcrp.2025.200405","DOIUrl":"10.1016/j.ijcrp.2025.200405","url":null,"abstract":"<div><h3>Background</h3><div>Serum uric acid (UA) has been associated with adverse outcomes in patients with heart failure. However, it remains inconclusive whether such association persists in patients with cardiorenal syndrome (CRS).</div></div><div><h3>Methods</h3><div>In a nationwide prospective cohort from China, 4907 adults hospitalized for heart failure were enrolled. Of them, 1284 had an estimated glomerular filtration rate (eGFR) &lt; 60 mL/min/1.73 m² at admission were included in this study. The Cox regression model was employed to evaluate the relationship between UA levels and mortality, major cardiovascular events (MACE), and hospitalization for heart failure (HHF). Additionally, Harrell’s concordance index was utilized to assess the incremental value of UA levels in predicting mortality.</div></div><div><h3>Results</h3><div>During a median follow-up of 3.28 years, hyperuricemia was associated with a 27 % increased risk of all-cause mortality (HR 1.27, 95 % confidence interval [CI] 1.08–1.49) and a 36 % increased risk of cardiovascular mortality (HR 1.36, 95 % CI 1.11–1.65), regardless of patients' eGFR levels. This relationship remained consistent throughout the whole follow-up period. Hyperuricemia increased the risk of 3-month MACE by 39 % (HR 1.39, 95 % CI 1.03–1.88), 3-month HHF by 47 % (HR 1.47, 95 % CI 1.11–1.95), and 1-year MACE by 26 % (HR 1.26, 95 % CI 1.02–1.57). The additive effect of uric acid levels in predicting mortality was also confirmed.</div></div><div><h3>Conclusions</h3><div>Serum UA levels possess significant value in prognosis of mortality, MACE, and HHF among patients with CRS. These findings underscore the importance of monitoring serum UA in the management of patients with CRS, as UA may provide valuable insights into risk stratification.</div></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"25 ","pages":"Article 200405"},"PeriodicalIF":1.9,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143874301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiovascular risk in newly diagnosed patients with type 2 diabetes mellitus: a nationwide, facility-based, cross-sectional study in Bangladesh","authors":"A.B.M. Kamrul-Hasan ,&nbsp;Muhammad Shah Alam ,&nbsp;Marufa Mustari ,&nbsp;Mohammad Abdul Hannan ,&nbsp;Emran Ur Rashid Chowdhury ,&nbsp;Sumon Rahman Chowdhury ,&nbsp;Md. Abu Jar Gaffar ,&nbsp;Swapan Kumar Singha ,&nbsp;Choman Abdullah Mohana ,&nbsp;Ershad Mondal ,&nbsp;Md. Shahinur Rahman ,&nbsp;Mohammad Motiur Rahman ,&nbsp;Sourav Sarker ,&nbsp;Md. Azizul Hoque ,&nbsp;Md. Rashedul Islam ,&nbsp;Md. Abdul Bari Robel ,&nbsp;Shahryar Ahmad ,&nbsp;Ahmed Ifrad Bin Raunak ,&nbsp;Nur-A-Musabber ,&nbsp;Md. Mostofa Kaisar ,&nbsp;Shahjada Selim","doi":"10.1016/j.ijcrp.2025.200399","DOIUrl":"10.1016/j.ijcrp.2025.200399","url":null,"abstract":"<div><h3>Aims</h3><div>Evidence on cardiovascular (CV) risk stratification in Bangladeshi patients with type 2 diabetes mellitus (T2DM) who are asymptomatic for cardiovascular disease (CVD) is limited. This study aimed to assess the 10-year CV risk in newly diagnosed patients with T2DM.</div></div><div><h3>Methods</h3><div>In 2023, a cross-sectional study was carried out at endocrinology clinics in tertiary hospitals throughout Bangladesh, involving newly diagnosed patients with T2DM aged 25 to 84 who had no prior history of CVD and were asymptomatic for the condition. CV risk was assessed and classified using QRISK3.</div></div><div><h3>Results</h3><div>1617 newly diagnosed patients with T2DM (age 44.92 ± 11.84 years, male 49.5 %) were analyzed. Their median QRISK3 score was 11.0 %, with 46.5 % at low, 25.7 % at moderate, and 27.8 % at high 10-year CV risk, respectively. The QRISK3 score increased with age for both men and women, with men consistently scoring higher than women in every age group. Among the age groups 25–39, 40–64, and 65–84, the percentages of patients with high 10-year CV risk were 3.3 %, 34.0 %, and 94.5 %, respectively. The median relative risk (RR) of CVD was 4.3. RR decreased with age for both sexes, and men had a lower RR than women across all age groups. A sleep duration of 6–9 h was associated with a lower 10-year CV risk.</div></div><div><h3>Conclusions</h3><div>Many newly diagnosed Bangladeshi patients with T2DM have substantial CV risk. QRISK3 can assist clinicians in predicting 10-year CV risk and choosing appropriate treatments to prevent CVD.</div></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"25 ","pages":"Article 200399"},"PeriodicalIF":1.9,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143785238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Holistic health: A key to managing atrial fibrillation","authors":"John Patrick C. Toledo","doi":"10.1016/j.ijcrp.2025.200402","DOIUrl":"10.1016/j.ijcrp.2025.200402","url":null,"abstract":"","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"25 ","pages":"Article 200402"},"PeriodicalIF":1.9,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143816926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Addressing the dangers of high sodium intake for a better health","authors":"Dalmacito A. Cordero Jr.","doi":"10.1016/j.ijcrp.2025.200403","DOIUrl":"10.1016/j.ijcrp.2025.200403","url":null,"abstract":"","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"25 ","pages":"Article 200403"},"PeriodicalIF":1.9,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143776392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reducing premature mortality from cardiovascular diseases in low and middle income countries: The role of Polypill in public health policy","authors":"Sadaf G. Sepanlou ,&nbsp;SeyedehFatemeh Mousavi ,&nbsp;Hossein Poustchi ,&nbsp;Fatemeh Malekzadeh ,&nbsp;Gholamreza Roshandel ,&nbsp;Reza Malekzadeh","doi":"10.1016/j.ijcrp.2025.200400","DOIUrl":"10.1016/j.ijcrp.2025.200400","url":null,"abstract":"<div><div>Premature deaths account for about half of all fatalities in developing countries. In low- and middle-income countries, cardiovascular diseases have consistently been the primary cause of premature mortality for men and women during the past three decades.</div><div>Current evidence indicates that fixed-dose combination therapy, the so-called Polypill, effectively reduces the burden of cardiovascular diseases, with greater benefits observed in combinations that include aspirin. Polypill demonstrates high adherence and an acceptable safety profile, with adverse drug events being comparable between the groups receiving treatment and those in the control group.</div><div>Therefore, this paper advocates for the broader implementation of Polypill in low and middle-income countries, emphasizing its efficacy in the primary and secondary prevention of cardiovascular diseases. The strategy could also benefit high-risk groups with special conditions, such as non-alcoholic fatty liver disease and chronic kidney disease. The cost-effectiveness of Polypill and its potential to address health inequities in low and middle-income countries underscore its value as a public health strategy. Policymakers are encouraged to consider Polypill as a viable option to enhance cardiovascular health outcomes and reduce premature deaths in low-resource settings.</div></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"25 ","pages":"Article 200400"},"PeriodicalIF":1.9,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143783690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between electronic cigarette use and cardiovascular disease among a United States representative population","authors":"Humza Naqvi ,&nbsp;Charles Searles","doi":"10.1016/j.ijcrp.2025.200401","DOIUrl":"10.1016/j.ijcrp.2025.200401","url":null,"abstract":"<div><div>Electronic cigarettes have become increasingly popular, and many people use them as a safer alternative to conventional cigarettes. However, the impact of electronic cigarette use on cardiovascular health is uncertain. Here, we queried national survey data to examine the relationship between electronic cigarette use and self-reported cardiovascular disease, and we identified an association between electronic cigarette use and angina and MI but not stroke or CHF.</div></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"25 ","pages":"Article 200401"},"PeriodicalIF":1.9,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143783691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Addressing the cardiometabolic risks of adolescents in developing countries","authors":"Dalmacito A. Cordero Jr","doi":"10.1016/j.ijcrp.2025.200398","DOIUrl":"10.1016/j.ijcrp.2025.200398","url":null,"abstract":"","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"25 ","pages":"Article 200398"},"PeriodicalIF":1.9,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143734685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of preventive strategies on IHD mortality in Alzheimer's disease","authors":"John Patrick C. Toledo","doi":"10.1016/j.ijcrp.2025.200397","DOIUrl":"10.1016/j.ijcrp.2025.200397","url":null,"abstract":"","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"25 ","pages":"Article 200397"},"PeriodicalIF":1.9,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143768765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The multifaceted significance of miR-155 in cardiovascular pathologies: Diagnostic and therapeutic implications","authors":"John Patrick C. Toledo","doi":"10.1016/j.ijcrp.2025.200395","DOIUrl":"10.1016/j.ijcrp.2025.200395","url":null,"abstract":"","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"25 ","pages":"Article 200395"},"PeriodicalIF":1.9,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143637761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}