International Journal of Cardiology Cardiovascular Risk and Prevention最新文献

{"title":"Hypertension and lung cancer in China (2002–2019): A nationwide study of temporal trends, demographic disparities, and independent risk associations","authors":"Yang Yu ,&nbsp;Chen Jiang ,&nbsp;Yan gao ,&nbsp;Dingqi Li ,&nbsp;Chongcheng Xi ,&nbsp;Quansheng Feng ,&nbsp;Rui He","doi":"10.1016/j.ijcrp.2025.200515","DOIUrl":"10.1016/j.ijcrp.2025.200515","url":null,"abstract":"<div><h3>Background</h3><div>Emerging evidence suggests a potential link between hypertension and cancer, yet the relationship between elevated blood pressure and lung cancer risk remains underexplored, particularly in large, population-based settings.</div></div><div><h3>Objective</h3><div>To investigate temporal trends in hypertension prevalence among lung cancer patients and to assess whether hypertension is independently associated with lung cancer risk in the Chinese adult population.</div></div><div><h3>Methods</h3><div>We analyzed data from 2,745,893 adults aged ≥18 years who participated in the China Chronic Disease and Risk Factor Surveillance (CCDRFS) program from 2002 to 2019. Trends in hypertension prevalence among lung cancer patients were assessed across demographic strata. Multivariable logistic regression models adjusted for age, sex, smoking, obesity, and region were used to estimate adjusted odds ratios (aORs) for lung cancer associated with hypertension.</div></div><div><h3>Results</h3><div>Among 168,427 lung cancer patients (6.1 % of total), 58.3 % had coexisting hypertension. Hypertension prevalence among lung cancer patients rose from 47.2 % in 2002 to 62.8 % in 2019, with sharper increases in rural (49.3 %–66.1 %) and western regions (50.4 %–66.9 %). After adjustment, hypertension was independently associated with lung cancer (aOR = 1.37; 95 % CI: 1.31–1.43), with stronger associations observed in females (aOR = 1.49), individuals aged ≥60 years (aOR = 1.54), non-smokers (aOR = 1.44), and obese participants (aOR = 1.46).</div></div><div><h3>Conclusions</h3><div>Hypertension is highly prevalent among lung cancer patients in China and appears to be independently associated with increased lung cancer risk. These findings suggest the need for integrated cardio-oncology surveillance and prevention strategies, particularly for high-risk subpopulations such as older adults, women, and non-smokers. Further prospective studies are warranted to explore the mechanisms underlying this association and to evaluate whether hypertension control may influence lung cancer burden.</div></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"27 ","pages":"Article 200515"},"PeriodicalIF":2.1,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145104931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of outcomes of direct oral anticoagulants versus vitamin K antagonists for atrial fibrillation and chronic kidney disease: a systematic review and meta-analysis","authors":"Bing Luo,&nbsp;Yueyun Jiang,&nbsp;Minyi Tan,&nbsp;Jingyan Yang,&nbsp;Yue Fan,&nbsp;Yili Chen","doi":"10.1016/j.ijcrp.2025.200511","DOIUrl":"10.1016/j.ijcrp.2025.200511","url":null,"abstract":"<div><h3>Objective</h3><div>To systematically evaluate the efficacy and safety of direct oral anticoagulants (DOAC) compared to vitamin K antagonists (VKA) for anticoagulation in patients with atrial fibrillation (AF) and chronic kidney disease (CKD).</div></div><div><h3>Methods</h3><div>PubMed, Embase, Web of Science, and the Cochrane Library were searched from their inception through May 2025 to collect relevant clinical studies comparing the use of DOAC versus VKA for the treatment of patients with AF combined with chronic kidney disease. Literature screening, data extraction, analysis, quality evaluation, and risk of bias assessment were conducted by independent reviewers. The outcomes of interest included all-cause mortality, cardiovascular death, stroke or systemic embolism, major bleeding, gastrointestinal bleeding, intracranial bleeding, myocardial infarction, and stroke. Analysis was performed using RevMan 5.4 software, with I² statistics employed to assess heterogeneity.</div></div><div><h3>Results</h3><div>16 studies were included in the analysis. Compared with VKA, DOAC can significantly reduced the risks of cardiovascular mortality (HR = 0.78; 95 %CI 0.70–0.87; P &lt; 0.05), major bleeding (HR = 0.79; 95 %CI 0.64–0.97; P &lt; 0.05), and intracranial hemorrhage (HR = 0.50; 95 %CI 0.37–0.66; P &lt; 0.05). No significant differences were observed between the DOAC and VKA groups regarding all-cause death (HR = 0.98; 95 %CI 0.81–1.19; P = 0.82), stroke or systemic embolism (HR = 0.84; 95 %CI 0.68–1.04; P = 0.12), gastrointestinal bleeding (HR = 0.87; 95 %CI 0.61–1.24; P = 0.43), myocardial infarction (HR = 0.98; 95 %CI 0.78–1.23; P = 0.84), or stroke (HR = 0.85; 95 %CI 0.72–1.00; P = 0.06). Overall, DOACs demonstrated superior efficacy in reducing cardiovascular mortality, major bleeding, and intracranial hemorrhage. Among patients with end-stage renal disease, those treated with DOACs showed a tendency toward reduced major bleeding (HR = 0.58; 95 % CI 0.50–0.68; P &lt; 0.05), gastrointestinal hemorrhage (HR = 0.65; 95 %CI 0.48–0.98 P &lt; 0.05), and intracranial hemorrhage (HR = 0.56; 95 % CI, 0.38–0.82; P &lt; 0.05). For patients without end-stage renal disease, the DOAC group had greater benefits in reducing the risks of all-cause death (HR = 0.91; 95 %CI 0.84–0.99; P = 0.03), cardiovascular mortality (HR = 0.77; 95 %CI 0.69–0.86; P &lt; 0.05), major bleeding (HR = 0.85; 95 %CI 0.77–0.83; P &lt; 0.05, and intracranial hemorrhage (HR = 0.42; 95 % CI, 0.28–0.65; P &lt; 0.05). Conversely, the VKA group was more effective in reducing the risk of gastrointestinal hemorrhage events (HR = 1.38; 95 % CI 1.13–1.68; P &lt; 0.05).</div></div><div><h3>Conclusion</h3><div>In patients with non-valvular AF complicated by CKD, the use of DOAC is associated with a moderate reduction in the risks of cardiovascular mortality, major bleeding, and intracranial hemorrhage. Among patients with end-stage renal disease, DOACs offer more significant ","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"27 ","pages":"Article 200511"},"PeriodicalIF":2.1,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145043944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Shared genetic associations between CHA2DS2-VASc score and cardio-embolic stroke: Insights from mendelian randomization based bioinformatics analysis","authors":"Kang Yuan ,&nbsp;Xianshu Huo ,&nbsp;Mengdi Xie ,&nbsp;Huaiming Wang ,&nbsp;Siyu Sun ,&nbsp;Kejia Deng ,&nbsp;Rui Liu ,&nbsp;Xinfeng Liu","doi":"10.1016/j.ijcrp.2025.200514","DOIUrl":"10.1016/j.ijcrp.2025.200514","url":null,"abstract":"<div><div>The CHA₂DS₂-VASc score is a risk assessment score to predict cardio-embolic stroke (CES), suggesting shared genetic susceptibility. This study aimed to explore the shared genetic association of genetically predicted CHA₂DS₂-VASc score and CES using multiple analytic frameworks. We conducted a comprehensive analysis of genetic data from 13 traits of CHA₂DS₂-VASc score and CES using summary statistics from large-scale genome-wide association studies (GWAS). We employed statistical methods such as linkage disequilibrium score regression (LDSC), cross-trait analysis, bidirectional Mendelian randomization, colocalization analysis and gene-based association analysis to explore genetic correlations and identify pleiotropic single nucleotide polymorphisms (SNPs) and shared genes. LDSC and Mendelian randomization analysis revealed a significant genetic correlation between CHA₂DS₂-VASc score and CES. Cross-trait and colocalization analysis identified 9 potential loci and 13 significant independent SNPs. Gene-based association analysis reported 9 genes significant across at least three methods, with IL6R being the shared gene identified by all four methods, highlighting potential shared biological mechanisms involving immune responses and inflammatory activities. In conclusion, our study revealed shared genetic associations between the genetically predicted CHA₂DS₂-VASc score and CES, which was supported by causal relationship, shared loci, and genetic correlation analyses.</div></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"27 ","pages":"Article 200514"},"PeriodicalIF":2.1,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145044760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing cardiovascular risk prediction in Asian populations: A machine learning approach integrated with digital health platforms","authors":"Sazzli Kasim ,&nbsp;Putri Nur Fatin Amir Rudin ,&nbsp;Xue Ning Kiew ,&nbsp;Nurulain Ibrahim ,&nbsp;Nafiza Mat Nasir ,&nbsp;Lim Bing Feng ,&nbsp;Hanis Hamidi ,&nbsp;Khairul Shafiq Ibrahim ,&nbsp;Raja Ezman Raja Shariff ,&nbsp;Suraya Abdul-Razak ,&nbsp;Kazuaki Negishi ,&nbsp;Sorayya Malek","doi":"10.1016/j.ijcrp.2025.200509","DOIUrl":"10.1016/j.ijcrp.2025.200509","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aimed to develop and validate a machine learning (ML)–based model for cardiovascular disease (CVD) risk prediction in a Malaysian cohort representative of the Southeast Asian population.</div></div><div><h3>Methods</h3><div>Data from the Responding to Increasing Cardiovascular Disease Prevalence (REDISCOVER) Study, including 10,044 participants, were analyzed, with 4,299 cases retained after exclusions. The dataset was split into training (70 %) and validation (30 %) subsets. Logistic Regression (LR), Random Forest (RF), and Support Vector Machine (SVM) models were developed using feature selection techniques such as recursive feature elimination (RFE) and sequential backward elimination (SBE). Model performance was evaluated using the area under the curve (AUC), sensitivity, specificity, calibration, and Net Reclassification Index (NRI).</div></div><div><h3>Findings</h3><div>Among the models evaluated, the SVM model with SBE-selected features performed best, achieving an AUC of 0.800. This was higher than the Framingham Risk Score (FRS; AUC = 0.693), Revised Pooled Cohort Equations (RPCE; AUC = 0.744), and WHO CVD charts (AUC = 0.741). NRI analysis showed significant improvements compared to FRS and RPCE (17.29 % and 14.23 %, respectively; p &lt; 0.00001). Calibration analyses indicated initial overprediction by ML models, which was mitigated by Platt scaling.</div></div><div><h3>Conclusion</h3><div>ML-based models incorporating regionally relevant variables demonstrated improved discrimination and reclassification compared with conventional risk scores in this Malaysian cohort. Further external validation is needed to establish their utility across broader Southeast Asian populations.</div></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"27 ","pages":"Article 200509"},"PeriodicalIF":2.1,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145104932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Smoking and long-term risks for morbidity and mortality after coronary artery bypass grafting","authors":"Emelie Johansson ,&nbsp;Malin Stenman ,&nbsp;Emma C. Hansson ,&nbsp;Carl-Johan Malm ,&nbsp;Sossio Perrotta ,&nbsp;Aldina Pivodic ,&nbsp;Anders Jeppsson ,&nbsp;Susanne J. Nielsen","doi":"10.1016/j.ijcrp.2025.200512","DOIUrl":"10.1016/j.ijcrp.2025.200512","url":null,"abstract":"<div><h3>Background</h3><div>We explored the association between smoking and long-term risks of morbidity and mortality in patients who had undergone coronary artery bypass grafting (CABG).</div></div><div><h3>Methods</h3><div>This population-based registry study included 27,434 patients (mean age 67.9 years, 18.2 % women), divided into: never smokers (n = 8,593), former smokers (n = 14,666) and current smokers (n = 4,175), who underwent CABG between 2010 and 2020. Data were collected from the SWEDEHEART registry. Three other mandatory registers provided data on comorbidities, social factors and outcome variables. Adjusted Cox regression models were used to estimate mortality and morbidity. The median follow-up was 5 (0–11) years.</div></div><div><h3>Results</h3><div>Current smokers were younger and had a higher proportion of previous myocardial infarction, heart failure, chronic respiratory disease, depression and low education compared with never smokers. Compared with never smokers, current smokers had higher risk for a major adverse cardiovascular event (MACE) (adjusted hazard ratio (aHR) 1.52, 95 % confidence interval (CI) 1.39–1.66), all-cause mortality (aHR 1.91, (1.71–2.14)) and stroke (aHR 1.49, (1.27–1.74)) but not for myocardial infarction (aHR 1.07, (0.91–1.26)). Compared with former smokers, current smokers had an increased risk for MACE (aHR 1.38, (1.27–1.49)), all-cause mortality (aHR 1.53, (1.39–1.69)), stroke (aHR 1.36, (1.18–1.56)), but not for myocardial infarction (aHR 1.15, (1.00–1.34)).</div></div><div><h3>Conclusions</h3><div>There was a strong association between smoking and long-term risk for mortality and morbidity after CABG. The highest risks were observed in current smokers. The results emphasize the importance of motivating CABG patients to smoking cessation before considering CABG as a treatment option.</div></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"27 ","pages":"Article 200512"},"PeriodicalIF":2.1,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145043945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronic emotional stress and mediating role of Interleukin-6 in the association with cardiometabolic disorders in a multiethnic middle-aged and older US population","authors":"Asma Hallab ,&nbsp;The Health and Aging Brain Study (HABS-HD) Study Team","doi":"10.1016/j.ijcrp.2025.200510","DOIUrl":"10.1016/j.ijcrp.2025.200510","url":null,"abstract":"<div><h3>Introduction</h3><div>Chronic emotional stress is a well-recognized risk factor for psychiatric and cardiometabolic disorders. The mediating role of low-grade inflammation in older, ethnically diverse populations has never been studied.</div></div><div><h3>Methods</h3><div>The multiethnic ≥50-year-old study population is a subset of the Health and Aging Brain Study: Health Disparities (HABS-HD) study. Adjusted logistic and linear regression were used to assess associations. Statistical mediation analysis with non-parametric bootstrapping of confidence intervals was used to determine the intermediate role of Interleukin-6 (IL-6).</div></div><div><h3>Results</h3><div>The study included 2173 participants (50–92 years). Black participants disclosed higher chronic stress levels than White and Hispanic participants. Having a chronic stress total score ≥ six points is associated with 53 % higher odds of disclosing concomitant cardiovascular disease (CVD) (adj.OR = 1.53 [1.10–2.53]), 31 % of Type-2 diabetes (T₂DM) (adj.OR = 1.31[1.06–1.62]), 23 % of hypertension (adj.OR = 1.23 [1.02–1.49]), and 30 % obesity (adj.OR = 1.3[1.09–1.55]). These associations were statistically mediated by IL-6 (12 % (<em>p-value</em>_FDR = 0.012) of the association with CVD, 17 % T₂DM (<em>p-value</em>_FDR&lt;0.001), 18 % hypertension (<em>p-value</em>_FDR&lt;0.001), and 29 % obesity (<em>p-value</em>_FDR = 0.005)).</div></div><div><h3>Conclusions</h3><div>The study highlights a further aspect of the pathophysiological mechanisms involved in the brain-body communication. While IL-6 partially explains statistical associations between chronic emotional stress and major cardiometabolic disorders, no causal effects can be inferred from this study owing to the cross-sectional design. Larger longitudinal studies are needed to better clarify the temporal relationship between the events and to build upon our findings.</div></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"27 ","pages":"Article 200510"},"PeriodicalIF":2.1,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145104929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic performance of left ventricular strain for predicting physiologically significant coronary artery disease","authors":"Pratya Rawangban ,&nbsp;Anusith Tunhasiriwet ,&nbsp;Rawish Wimolwattanaphan ,&nbsp;Chanwit Wuttichaipradit ,&nbsp;Piyoros Lertsanguansinchai","doi":"10.1016/j.ijcrp.2025.200503","DOIUrl":"10.1016/j.ijcrp.2025.200503","url":null,"abstract":"<div><h3>Background</h3><div>Coronary artery disease (CAD) remains a leading cause of morbidity and mortality worldwide. While invasive coronary angiography is the gold standard for diagnosing obstructive CAD, contemporary guidelines advocate for initial evaluation using resting transthoracic echocardiography. The role of left ventricular global longitudinal strain (LV GLS) as a screening tool in the diagnosis of obstructive CAD remains unclear.</div></div><div><h3>Objective</h3><div>To evaluate the diagnostic utility of LV GLS in predicting physiologically significant CAD as confirmed by intracoronary physiological tests such as fractional flow reserve (FFR) and/or non-hyperemic pressure ratios (NHPRs).</div></div><div><h3>Methods</h3><div>We conducted a retrospective cohort study at the Cardiac Center, Chulabhorn Hospital, Thailand, enrolling patients with suspected CAD who underwent coronary angiography with FFR and/or NHPRs between August 2018 and September 2024. Resting echocardiograms were reevaluated for LV GLS. Receiver operating characteristic (ROC) analysis was performed to assess the predictive value of LV GLS for physiologically significant CAD. A multivariate model incorporating LV GLS patterns and clinical parameters was also developed.</div></div><div><h3>Results</h3><div>Of the 207 patients analyzed, 99 (47 %) had positive physiological test results (FFR ≤0.80 and/or NHPR ≤0.89). The average LV GLS was lower in the physiologically positive group (−15.6 %) compared to the negative group (−16.8 %), though this difference was not statistically significant. ROC analysis of average LV GLS yielded an area under the curve (AUC) of 0.56 (95 % CI: 0.48–0.64, p = 0.130). However, the ischemic Bull's-eye pattern derived from LV GLS demonstrated high sensitivity (93 %) and negative predictive value (87 %). Multivariate analysis identified central aortic pulse pressure (OR 1.02, 95 % CI = 1.00–1.04, p = 0.042) and the ischemic Bull's-eye pattern (OR 16.33, 95 % CI = 5.16–51.72, p &lt; 0.001) as independent predictors of physiologically significant CAD. The combined model achieved an AUC of 0.76, outperforming both the average LV GLS alone and 2024 ESC clinical risk factor-based likelihood.</div></div><div><h3>Conclusions</h3><div>While the average LV GLS is not a robust predictor of physiologically significant CAD, the ischemic Bull's-eye pattern derived from LV GLS offers high sensitivity and negative predictive value. When combined with central aortic pulse pressure, this approach enhances the diagnostic accuracy for physiologically significant CAD. These findings support the integration of ischemic Bull's-eye patterns derived from LV GLS and central aortic pulse pressure into initial CAD screening protocols.</div></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"27 ","pages":"Article 200503"},"PeriodicalIF":2.1,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145044761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heart failure care in low-middle income countries: Time for incorporating gender-specific guidelines?","authors":"P.B. Jayagopal","doi":"10.1016/j.ijcrp.2025.200508","DOIUrl":"10.1016/j.ijcrp.2025.200508","url":null,"abstract":"","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"27 ","pages":"Article 200508"},"PeriodicalIF":2.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145010339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Promoting life's essential 8 to advance global adolescent cardiovascular health","authors":"Jason M. Nagata ,&nbsp;Nathan D. Nguyen ,&nbsp;Christiane K. Helmer ,&nbsp;Jennifer H. Wong ,&nbsp;Abubakr A.A. Al-shoaibi ,&nbsp;Holly C. Gooding","doi":"10.1016/j.ijcrp.2025.200507","DOIUrl":"10.1016/j.ijcrp.2025.200507","url":null,"abstract":"","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"27 ","pages":"Article 200507"},"PeriodicalIF":2.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145019133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to “Letter to the Editor: Comments on gender differences in acute heart failure study”","authors":"P.B. Jayagopal ,&nbsp;C.N. Manjunath ,&nbsp;A. Jabir ,&nbsp;Sridhar L. Sastry ,&nbsp;Veena Nanjappa ,&nbsp;P.R. Vaidyanathan ,&nbsp;Johny Joseph ,&nbsp;Soma Sekhar Ghanta ,&nbsp;P. Manokar ,&nbsp;Nitin Kabra ,&nbsp;Dharmendra Jain ,&nbsp;Vinod Sharma ,&nbsp;Trinath Kumar Mishra ,&nbsp;R. Badri Narayanan ,&nbsp;Narendra Jathappa ,&nbsp;Gautam Rege ,&nbsp;Sunil Modi ,&nbsp;S.N. Routray ,&nbsp;T.R. Raghu ,&nbsp;Rabin Chakraborty ,&nbsp;V.K. Chopra","doi":"10.1016/j.ijcrp.2025.200505","DOIUrl":"10.1016/j.ijcrp.2025.200505","url":null,"abstract":"","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"27 ","pages":"Article 200505"},"PeriodicalIF":2.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145010338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}