International Journal of Cardiology Cardiovascular Risk and Prevention最新文献

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No death gap, but a care gap: Rethinking gender and heart failure in India and the Philippines 没有死亡差距,但有护理差距:重新思考印度和菲律宾的性别和心力衰竭
IF 1.9
International Journal of Cardiology Cardiovascular Risk and Prevention Pub Date : 2025-07-03 DOI: 10.1016/j.ijcrp.2025.200461
Jose Eric M. Lacsa, Andylyn M. Simeon
{"title":"No death gap, but a care gap: Rethinking gender and heart failure in India and the Philippines","authors":"Jose Eric M. Lacsa, Andylyn M. Simeon","doi":"10.1016/j.ijcrp.2025.200461","DOIUrl":"10.1016/j.ijcrp.2025.200461","url":null,"abstract":"","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"26 ","pages":"Article 200461"},"PeriodicalIF":1.9,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144563806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From classroom to clinic: Social determinants of adolescent cardiometabolic health in the Global South 从教室到诊所:全球南方青少年心脏代谢健康的社会决定因素
IF 1.9
International Journal of Cardiology Cardiovascular Risk and Prevention Pub Date : 2025-07-01 DOI: 10.1016/j.ijcrp.2025.200462
Jose Eric M. Lacsa
{"title":"From classroom to clinic: Social determinants of adolescent cardiometabolic health in the Global South","authors":"Jose Eric M. Lacsa","doi":"10.1016/j.ijcrp.2025.200462","DOIUrl":"10.1016/j.ijcrp.2025.200462","url":null,"abstract":"","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"26 ","pages":"Article 200462"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144536130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development and validation of a predictive model for in-hospital mortality in patients with coronary heart disease and renal insufficiency 冠心病合并肾功能不全患者住院死亡率预测模型的建立与验证
IF 1.9
International Journal of Cardiology Cardiovascular Risk and Prevention Pub Date : 2025-07-01 DOI: 10.1016/j.ijcrp.2025.200463
Yahui Li , Hongsen Cai , Wei Zheng , Meijie Wang , Man Huang , Luyun Wang , Daowen Wang , Chunxia Zhao , Wenguang Hou , Hu Ding , Yan Wang , Hongling Zhu
{"title":"Development and validation of a predictive model for in-hospital mortality in patients with coronary heart disease and renal insufficiency","authors":"Yahui Li ,&nbsp;Hongsen Cai ,&nbsp;Wei Zheng ,&nbsp;Meijie Wang ,&nbsp;Man Huang ,&nbsp;Luyun Wang ,&nbsp;Daowen Wang ,&nbsp;Chunxia Zhao ,&nbsp;Wenguang Hou ,&nbsp;Hu Ding ,&nbsp;Yan Wang ,&nbsp;Hongling Zhu","doi":"10.1016/j.ijcrp.2025.200463","DOIUrl":"10.1016/j.ijcrp.2025.200463","url":null,"abstract":"<div><h3>Background</h3><div>Coronary Heart Disease (CHD) with renal insufficiency is a significant global health issue. This study aimed to develop and validate a predictive model for in-hospital mortality to enable early risk identification in these patients.</div></div><div><h3>Methods</h3><div>We analyzed data from 11,830 CHD patients with renal insufficiency treated at Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei Province, China (1994–2023). Among 113 clinical variables, five key features—age, high-sensitivity C-reactive protein (hs-CRP), estimated glomerular filtration rate (eGFR), creatine kinase (CK), and blood urea—were selected using Recursive Feature Elimination. Six machine learning models (Random Forest, XGBoost, Decision Tree, Neural Network, Logistic Regression, and Support Vector Machine) were developed and assessed for discrimination, calibration, and clinical utility. Temporal validation was performed using data from May 16, 2023 to October 31, 2024. SHapley Additive exPlanations (SHAP) were used for model interpretation.</div></div><div><h3>Results</h3><div>Of the 11,830 patients, 694 (5.9 %) died during hospitalization. Among the six models, XGBoost showed the best overall performance in the test set, achieving the highest AUC (0.926), lowest Brier score (0.034), highest accuracy (0.957), and balanced sensitivity (0.381) and F1 score (0.512). Decision curve analysis confirmed its superior clinical utility. In a temporally independent validation cohort of 5983 patients, XGBoost maintained strong predictive performance (AUC = 0.901), demonstrating excellent robustness and generalizability.</div></div><div><h3>Conclusions</h3><div>The XGBoost-based model accurately predicts in-hospital mortality in CHD patients with renal insufficiency, supporting early risk stratification and clinical decision-making.</div></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"26 ","pages":"Article 200463"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144524324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ITACARE-P/SIGG/SIGOT/SICGE position paper on elderly cardiac patient referral to cardiac rehabilitation ITACARE-P/SIGG/SIGOT/SICGE关于老年心脏病患者转介到心脏康复的立场文件
IF 1.9
International Journal of Cardiology Cardiovascular Risk and Prevention Pub Date : 2025-07-01 DOI: 10.1016/j.ijcrp.2025.200454
Francesco Giallauria , Angela Sciacqua , Alessandra Pratesi , Claudio De Lucia , Dario Leosco , Enrico Occhiuzzi , Angelo Scuteri , Andrea Ungar , Carlo Vigorito , Francesco Fattirolli , Samuele Baldasseroni (Document Reviewers) , Luigina Guasti (Document Reviewers) , Francesco Maranta (Document Reviewers) , Gian Francesco Mureddu (Document Reviewers) , Matteo Ruzzolini (Document Reviewers) , Maria Vittoria Silverii (Document Reviewers) , Elio Venturini (Document Reviewers) , Francesco Vetta (Document Reviewers) , Alessandro Boccanelli (Document Reviewers) , Lorenzo Palleschi (Document Reviewers) , Marco Ambrosetti (Document Reviewers)
{"title":"ITACARE-P/SIGG/SIGOT/SICGE position paper on elderly cardiac patient referral to cardiac rehabilitation","authors":"Francesco Giallauria ,&nbsp;Angela Sciacqua ,&nbsp;Alessandra Pratesi ,&nbsp;Claudio De Lucia ,&nbsp;Dario Leosco ,&nbsp;Enrico Occhiuzzi ,&nbsp;Angelo Scuteri ,&nbsp;Andrea Ungar ,&nbsp;Carlo Vigorito ,&nbsp;Francesco Fattirolli ,&nbsp;Samuele Baldasseroni (Document Reviewers) ,&nbsp;Luigina Guasti (Document Reviewers) ,&nbsp;Francesco Maranta (Document Reviewers) ,&nbsp;Gian Francesco Mureddu (Document Reviewers) ,&nbsp;Matteo Ruzzolini (Document Reviewers) ,&nbsp;Maria Vittoria Silverii (Document Reviewers) ,&nbsp;Elio Venturini (Document Reviewers) ,&nbsp;Francesco Vetta (Document Reviewers) ,&nbsp;Alessandro Boccanelli (Document Reviewers) ,&nbsp;Lorenzo Palleschi (Document Reviewers) ,&nbsp;Marco Ambrosetti (Document Reviewers)","doi":"10.1016/j.ijcrp.2025.200454","DOIUrl":"10.1016/j.ijcrp.2025.200454","url":null,"abstract":"<div><div>The Italian Association for Cardiovascular Rehabilitation and Prevention (ITACARE-P) together with the Società Italiana di Gerontologia e Geriatria (SIGG); Società Italiana di Geriatria Ospedale e Territorio (SIGOT); SICGE, Società Italiana di Cardiologia Geriatrica (SICGE) released a joint position paper to guide referrals of elderly cardiovascular patients discharged from Geriatric wards to Cardiac Rehabilitation (CR) facilities. The document provides rationale and operative recommendations for appropriateness (i.e. qualifying diagnosis) and priority criteria to overcome mismatch between potential demand and effective supply of CR programmes. In case of no-referral due to logistic restraints, the document recommends the adoption of best alternatives to CR for disability reduction, better prognosis, and improvement of quality of life. The joint position paper is also aimed at promoting the consideration of Geriatric Medicine as a potential stakeholder of CR.</div></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"26 ","pages":"Article 200454"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144597491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predicting circadian syndrome by obesity indices in middle-aged and older Chinese: evidence from the China Health and Retirement Longitudinal Study 中国中老年肥胖指数预测昼夜节律综合征:来自中国健康与退休纵向研究的证据
IF 1.9
International Journal of Cardiology Cardiovascular Risk and Prevention Pub Date : 2025-07-01 DOI: 10.1016/j.ijcrp.2025.200465
Nian Liu , Siyan Jia
{"title":"Predicting circadian syndrome by obesity indices in middle-aged and older Chinese: evidence from the China Health and Retirement Longitudinal Study","authors":"Nian Liu ,&nbsp;Siyan Jia","doi":"10.1016/j.ijcrp.2025.200465","DOIUrl":"10.1016/j.ijcrp.2025.200465","url":null,"abstract":"<div><h3>Objective</h3><div>To predict the optimal cut-off values for screening and predicting circadian syndrome (CircS) in a middle-aged and older population using 11 obesity-related indices.</div></div><div><h3>Methods</h3><div>Data was obtained from the China Health and Retirement Longitudinal Study (CHARLS) database, including 9265 middle-aged and older people. We examined 11 indices, including waist circumference (WC), body mass index (BMI), waist-height ratio (WHtR), visceral adiposity index (VAI), a body shape index (ABSI), body roundness index (BRI), lipid accumulation product index (LAP), conicity index (CI), Chinese visceral adiposity index (CVAI), weight-adjusted-waist index (WWI), and cardiometabolic index (CMI). The receiver operating characteristic curve (ROC) was used to determine the usefulness of indicators for screening for CircS in middle-aged. Binary logistic regression analysis was performed to analyze the correlations between 11 obesity-related indices and CircS as well as its components.</div></div><div><h3>Results</h3><div>A total of 9265 middle-aged and older people were included in this study, and the CircS prevalence was 35.60 %. The percentage of males diagnosed with CircS was 25.99 %, and the females was 44.08 %. In males, CMI had the highest AUC. In females, CVAI was the best predictor. Logistic analysis revealed all obesity-related indices were significantly associated with CircS in both males and females (all <em>P</em> &lt; 0.001), and the correlations were stronger in females than in males.</div></div><div><h3>Conclusion</h3><div>All 11 obesity-related indices had good predictive power, with CMI and CVAI performing as the best predictor, and ABSI was the weakest predictor in males and females, respectively. In addition, the associations among all obesity-related indices and CircS were stronger in females than in males.</div></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"26 ","pages":"Article 200465"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144572757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of mHealth on health literacy in patients after cardiac rehabilitation 移动健康对心脏康复患者健康素养的影响
IF 1.9
International Journal of Cardiology Cardiovascular Risk and Prevention Pub Date : 2025-06-26 DOI: 10.1016/j.ijcrp.2025.200460
Ioannis Skalidis, Serigne Cheikh Tidiane Ndao, Thierry Unterseeh, Stephane Champagne, Philippe Garot
{"title":"Effect of mHealth on health literacy in patients after cardiac rehabilitation","authors":"Ioannis Skalidis,&nbsp;Serigne Cheikh Tidiane Ndao,&nbsp;Thierry Unterseeh,&nbsp;Stephane Champagne,&nbsp;Philippe Garot","doi":"10.1016/j.ijcrp.2025.200460","DOIUrl":"10.1016/j.ijcrp.2025.200460","url":null,"abstract":"","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"26 ","pages":"Article 200460"},"PeriodicalIF":1.9,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144523977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter to the editor: “The association between Sugar Sweetened Beverages and glycemic profile among children and youth: A systematic review and dose-response meta-analysis” 致编辑的信:“含糖饮料与儿童和青少年血糖状况之间的关系:系统回顾和剂量反应荟萃分析”
IF 1.9
International Journal of Cardiology Cardiovascular Risk and Prevention Pub Date : 2025-06-23 DOI: 10.1016/j.ijcrp.2025.200459
Saraswati Sah , Renu Sah
{"title":"Letter to the editor: “The association between Sugar Sweetened Beverages and glycemic profile among children and youth: A systematic review and dose-response meta-analysis”","authors":"Saraswati Sah ,&nbsp;Renu Sah","doi":"10.1016/j.ijcrp.2025.200459","DOIUrl":"10.1016/j.ijcrp.2025.200459","url":null,"abstract":"","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"26 ","pages":"Article 200459"},"PeriodicalIF":1.9,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144365512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Usefulness of the AHEAD score for prediction of all-cause death in patients with acute and chronic coronary syndromes AHEAD评分预测急性和慢性冠脉综合征患者全因死亡的有效性
IF 1.9
International Journal of Cardiology Cardiovascular Risk and Prevention Pub Date : 2025-06-20 DOI: 10.1016/j.ijcrp.2025.200457
Shunsuke Tamaki , Akinori Higaki , Hiroshi Kawakami , Kazuhisa Nishimura , Katsuji Inoue , Shuntaro Ikeda , Osamu Yamaguchi , Naoyuki Akashi , Tetsuya Matoba , Takahide Kohro , Tomoyuki Kabutoya , Kazuomi Kario , Arihiro Kiyosue , Masaharu Nakayama , Yoshihiro Miyamoto , Kenichi Tsujita , Hideo Fujita , Ryozo Nagai
{"title":"Usefulness of the AHEAD score for prediction of all-cause death in patients with acute and chronic coronary syndromes","authors":"Shunsuke Tamaki ,&nbsp;Akinori Higaki ,&nbsp;Hiroshi Kawakami ,&nbsp;Kazuhisa Nishimura ,&nbsp;Katsuji Inoue ,&nbsp;Shuntaro Ikeda ,&nbsp;Osamu Yamaguchi ,&nbsp;Naoyuki Akashi ,&nbsp;Tetsuya Matoba ,&nbsp;Takahide Kohro ,&nbsp;Tomoyuki Kabutoya ,&nbsp;Kazuomi Kario ,&nbsp;Arihiro Kiyosue ,&nbsp;Masaharu Nakayama ,&nbsp;Yoshihiro Miyamoto ,&nbsp;Kenichi Tsujita ,&nbsp;Hideo Fujita ,&nbsp;Ryozo Nagai","doi":"10.1016/j.ijcrp.2025.200457","DOIUrl":"10.1016/j.ijcrp.2025.200457","url":null,"abstract":"<div><h3>Background</h3><div>The AHEAD (A: atrial fibrillation; H: hemoglobin; E: elderly; A: abnormal renal parameters; D: diabetes mellitus) score was developed to predict all-cause death (ACD) in patients with heart failure. However, its predictive value for ACD compared to the CHADS<sub>2</sub> score in patients with coronary artery disease (CAD) remains unknown.</div></div><div><h3>Methods</h3><div>This retrospective multicenter cohort study analyzed data of the patients who underwent percutaneous coronary intervention for acute (ACS) or chronic coronary syndromes (CCS) using the Clinical Deep Data Accumulation System (CLIDAS) database. The AHEAD score was calculated by assigning 1 point each for atrial fibrillation, anemia, age &gt;70 years, elevated creatinine levels (&gt;130 μmol/L), and diabetes mellitus.</div></div><div><h3>Results</h3><div>In total, 9033 patients were enrolled between April 2013 and March 2019. Cox multivariate analysis revealed that both the AHEAD and CHADS<sub>2</sub> scores were independently associated with ACD in patients with ACS and CCS (hazard ratio [HR], 1.91 [95 % CI, 1.70–2.14] for ACS and 1.72 [1.54–1.92] for CCS, and HR 1.17 [1.06–1.29] for ACS and 1.18 [1.08–1.29] for CCS, respectively). However, receiver operating characteristic curve analysis demonstrated that the AHEAD score had a significantly higher predictive value for ACD compared to the CHADS<sub>2</sub> score in both ACS and CCS. A significant difference was found in the rate of ACD among patients stratified by the AHEAD score in both groups.</div></div><div><h3>Conclusions</h3><div>The AHEAD score demonstrated superior predictive value for ACD compared to the CHADS<sub>2</sub> score in patients with CAD, regardless of whether they had ACS or CCS.</div></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"26 ","pages":"Article 200457"},"PeriodicalIF":1.9,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144364837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prognostic value of RS1333040 polymorphism in the ANRIL gene for coronary artery lesions and cardiovascular events in acute myocardial infarction patients ANRIL基因RS1333040多态性对急性心肌梗死患者冠状动脉病变及心血管事件的预后价值
IF 1.9
International Journal of Cardiology Cardiovascular Risk and Prevention Pub Date : 2025-06-19 DOI: 10.1016/j.ijcrp.2025.200458
Nga Thi Ngoc Pham , Lien Nguyen Thao Tran , Cang Huynh Trung , Hoang Minh Phan , Dung The Bui , Chau Minh Tran , Thuc Tri Nguyen , Phuong Minh Nguyen , An Viet Tran
{"title":"Prognostic value of RS1333040 polymorphism in the ANRIL gene for coronary artery lesions and cardiovascular events in acute myocardial infarction patients","authors":"Nga Thi Ngoc Pham ,&nbsp;Lien Nguyen Thao Tran ,&nbsp;Cang Huynh Trung ,&nbsp;Hoang Minh Phan ,&nbsp;Dung The Bui ,&nbsp;Chau Minh Tran ,&nbsp;Thuc Tri Nguyen ,&nbsp;Phuong Minh Nguyen ,&nbsp;An Viet Tran","doi":"10.1016/j.ijcrp.2025.200458","DOIUrl":"10.1016/j.ijcrp.2025.200458","url":null,"abstract":"<div><h3>Background</h3><div>The <em>ANRIL</em> gene is involved in atherosclerotic processes and acute myocardial infarction (AMI) initiation. The <em>rs1333040</em> polymorphism shows potential association with coronary artery lesions and cardiovascular events in AMI patients, though data remains limited.</div></div><div><h3>Objectives</h3><div>To determine the prognostic value of the <em>rs1333040 ANRIL</em> gene polymorphism for coronary artery lesions and cardiovascular events in AMI patients.</div></div><div><h3>Materials and methods</h3><div>A cross-sectional descriptive study with longitudinal follow-up, conducted at the Interventional Cardiology Department of Can Tho Central General Hospital from October 2022 to June 2024. AMI patients underwent clinical examination, genetic sequencing, and cardiovascular event monitoring.</div></div><div><h3>Results</h3><div>Among 150 patients (mean age 63.8 ± 10.3 years, 70.7 % male), genotype distribution showed TT as the most prevalent (55.3 %), TC (38.7 %), and CC (6.0 %). Diabetes mellitus was more prevalent in the TT genotype (28.9 %) versus TC (12.1 %) and CC (11.1 %). Severe coronary artery lesions were more common in TT genotype patients (65.7 % vs. 45.4 %; p &lt; 0.05), with the T allele identified as a risk allele (OR = 2.22; 95 % CI: 1.29–3.81; p &lt; 0.05). Multi-vessel coronary artery disease (CAD) was also more frequent in TT genotype patients (59.8 % vs. 49.2 %; p &lt; 0.05). At the 9-month follow-up, event rates were: mortality 4.0 %, stroke 0.7 %, HF hospitalization 6.0 %, and MACE 10.7 %. Independent predictors for MACE initiation included age (HR = 1.05), diabetes (HR = 2.98), TT genotype (HR = 3.63), and T allele (HR = 3.39).</div></div><div><h3>Conclusion</h3><div>AMI patients with the T allele of the <em>rs1333040 ANRIL</em> gene show more severe coronary lesions, higher multi-vessel disease risk, and poorer prognosis with increased MACE event probability.</div></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"26 ","pages":"Article 200458"},"PeriodicalIF":1.9,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144364830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk assessment and prevention of cardiovascular events in patients with obstructive sleep apnea syndrome: A narrative review 阻塞性睡眠呼吸暂停综合征患者心血管事件的风险评估和预防:一项叙述性综述
IF 1.9
International Journal of Cardiology Cardiovascular Risk and Prevention Pub Date : 2025-06-19 DOI: 10.1016/j.ijcrp.2025.200455
Bin Li, HuiQian Yang, XiaoXu Lv, Xu Guo, FengLei Xu, XiaoMing Li
{"title":"Risk assessment and prevention of cardiovascular events in patients with obstructive sleep apnea syndrome: A narrative review","authors":"Bin Li,&nbsp;HuiQian Yang,&nbsp;XiaoXu Lv,&nbsp;Xu Guo,&nbsp;FengLei Xu,&nbsp;XiaoMing Li","doi":"10.1016/j.ijcrp.2025.200455","DOIUrl":"10.1016/j.ijcrp.2025.200455","url":null,"abstract":"<div><h3>Study objectives</h3><div>Obstructive sleep apnea syndrome (OSAS) is a causative agent of a wide range of chronic diseases, and its target organ damage is characterized by cardiovascular complications that are most common and severe. The primary objective of long-term intervention for OSAS is not only to correct the sleep architecture and reduce the incidence of hypoxemia, but also to alleviate the cardiovascular system's burden, decrease the risk of cardiovascular disease, and enhance patients' quality of life.</div></div><div><h3>Methods</h3><div>A literature search of PubMed, SCOPUS, and Google Scholar was conducted from January 1, 2019, to May 30, 2024. A comprehensive narrative review of studies related to the impact of OSAS on cardiovascular events in the last five years was also conducted. This includes an overview of the incidence, physiologic mechanisms, risk indicators, and interventions for OSAS and various cardiovascular diseases.</div></div><div><h3>Results</h3><div>Recent literature and studies have shown that there is a significant correlation between the prevalence of OSAS and the risk of cardiovascular disease, and that some unique dynamic factors such as shift work disorders play an important role in the assessment of the risk of cardiovascular events in patients with OSAS; however, new diagnostic tools and therapeutic strategies need to be further researched and developed to better meet the needs of clinical management.</div></div><div><h3>Conclusions</h3><div>A comprehensive assessment of the cardiovascular risk associated with OSAS, utilizing the necessary screening tools and targeted interventions, including the application of drugs, surgery, CPAP, or lifestyle modifications, can effectively reduce or even prevent damage to its target organs. The main goal of long-term intervention for OSAS is not only to correct the sleep architecture and reduce the occurrence of hypoxemia, but also to reduce the burden on the cardiovascular system, reduce the risk of cardiovascular disease, and improve the quality of life of patients.</div></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"26 ","pages":"Article 200455"},"PeriodicalIF":1.9,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144364842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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