{"title":"Addressing hypertension and obesity in the Philippines: Collaborative effort by the public and other institutions","authors":"Dalmacito A. Cordero","doi":"10.1016/j.ijcrp.2025.200419","DOIUrl":"10.1016/j.ijcrp.2025.200419","url":null,"abstract":"","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"25 ","pages":"Article 200419"},"PeriodicalIF":1.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143899745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gregor Verček , Tjaša Furlan , Dalibor Gavrić , Mitja Lainščak , Jerneja Farkaš Lainščak , Irena Ograjenšek , Petra Došenović Bonča , Borut Jug
{"title":"Statins for secondary prevention in women with atherosclerotic vascular disease: A nation-wide analysis of 24,665 women hospitalized for coronary, cerebrovascular or peripheral artery disease","authors":"Gregor Verček , Tjaša Furlan , Dalibor Gavrić , Mitja Lainščak , Jerneja Farkaš Lainščak , Irena Ograjenšek , Petra Došenović Bonča , Borut Jug","doi":"10.1016/j.ijcrp.2025.200415","DOIUrl":"10.1016/j.ijcrp.2025.200415","url":null,"abstract":"<div><h3>Background</h3><div>Statin therapy is recommended for secondary prevention of atherosclerotic vascular disease (ASCVD) based on randomized trials, which enrolled mostly men with coronary artery disease (CAD), whereas women and patients with cerebrovascular (CVD) and peripheral artery disease (PAD) were under-represented. We analyzed the effectiveness of statin therapy uptake in a nation-wide cohort of women hospitalized for ASCVD.</div></div><div><h3>Methods</h3><div>Women hospitalized for CAD, CVD, or PAD, including aortic disease, between 2015 and 2021 were retrospectively identified by linking the national hospital database, medicines reimbursement claims, and national mortality registry. The association of statin uptake within 30 days post-discharge with clinical outcomes (all-cause mortality and cardiovascular hospitalizations) was assessed by Kaplan-Meier curves and Cox proportional hazards regression model with propensity score-derived inverse probability of treatment weights and a 30-day landmark period.</div></div><div><h3>Results</h3><div>We included 24,665 women with ASCVD – 14,419 with CAD, 5,427 with CVD, and 4,819 with PAD. Overall, the median age was 73 (64–81) years. The rates of statin uptake were 50 % for women with CAD, 60 % for CVD and 28 % for PAD. Statin therapy uptake was associated with a reduction in all-cause mortality and cardiovascular hospitalizations across all three major types of ASCVD: hazard ratio (HR) 0.88, 95 % confidence interval (CI) 0.83–0.93, p = 0.001 for CAD, HR 0.87, 95 % CI 0.80–0.94, p = 0.006 for PAD, and HR 0.72, 95 % CI 0.66–0.78, p < 0.001 for CVD.</div></div><div><h3>Conclusion</h3><div>Statin therapy is associated with reduced all-cause mortality and cardiovascular hospital readmissions in women with all major types of ASCVD.</div></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"25 ","pages":"Article 200415"},"PeriodicalIF":1.9,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143879307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Meng Deng , Didi Wen , Yujie Song , Linli Zhao , Yang Cui , Jialin Xin , Rui Liu , Yufeng Qiu , Dongxu Yan , Wei Yi , Minwen Zheng , Yang Sun
{"title":"Correlation between blood pressure control levels and long-term patency of saphenous vein grafts after coronary artery bypass grafting: a retrospective case-control study","authors":"Meng Deng , Didi Wen , Yujie Song , Linli Zhao , Yang Cui , Jialin Xin , Rui Liu , Yufeng Qiu , Dongxu Yan , Wei Yi , Minwen Zheng , Yang Sun","doi":"10.1016/j.ijcrp.2025.200414","DOIUrl":"10.1016/j.ijcrp.2025.200414","url":null,"abstract":"<div><h3>Background</h3><div>The impact of aggressive blood pressure (BP) control (<130/80 mmHg) on vein graft disease progression following coronary artery bypass grafting remains unclear. This study evaluated the relationship between BP control on long-term graft patency in patients with hypertension post -coronary artery bypass grafting (CABG).</div></div><div><h3>Methods</h3><div>This retrospective, single-center, non-blinded case-control study initially enrolled 500 patients who underwent CABG at the Department of Cardiovascular Surgery, Xijing Hospital. Among them, 311 patients with comorbid hypertension and underwent coronary computed tomography angiography (CCTA) within three years postoperatively. Ultimately, 276 patients completed the follow-up of third year postoperatively and were included in the final statistical analysis. We conducted the correlation analysis between the BP control of the patients and the patency of long-term graft patency.</div></div><div><h3>Results</h3><div>Three years post-CABG, BP remained higher in the occlusion group (P < 0.05). The utilization rates of angiotensin-converting enzyme inhibitor/angiotensin receptor blocker (ACEI/ARB) and calcium channel blockers (CCB) were higher in the non-occlusion group (68.11 % vs. 52.75 %, <em>P</em> = 0.013; 62.16 % vs. 48.35 %, <em>P</em> = 0.029). Logistic regression identified postoperative BP as an independent risk factor for vein graft occlusion (per patient, odds ratio [OR], 3.098; 95 % confidence interval [CI] 1.841–5.214, <em>P</em> < 0.001; per graft, OR, 2.600; 95 % CI 1.738–3.889, <em>P</em> < 0.001). No significant correlation was found between antihypertensive regimens and long-term vein graft patency.</div></div><div><h3>Conclusions</h3><div>Patients with hypertension whose BP was above 130/80 mmHg after CABG were more likely to develop vein graft restenosis. No significant correlation was observed between postoperative antihypertensive regimen and long-term vein graft patency post-CABG.</div></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"25 ","pages":"Article 200414"},"PeriodicalIF":1.9,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143906910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adriana Lääti , Oskari Somerpalo , Konsta Teppo , Jenni Vire , Matti Viitanen , Ville Langén
{"title":"Association between educational attainment and blood pressure in older adults: a study of two Finnish generational cohorts born 20 years apart","authors":"Adriana Lääti , Oskari Somerpalo , Konsta Teppo , Jenni Vire , Matti Viitanen , Ville Langén","doi":"10.1016/j.ijcrp.2025.200412","DOIUrl":"10.1016/j.ijcrp.2025.200412","url":null,"abstract":"<div><h3>Background</h3><div>This study compares the association between educational attainment and blood pressure (BP) in two Finnish cohorts of older adults, born 20 years apart.</div></div><div><h3>Methods</h3><div>All 70-year-old residents of Turku, Finland, were surveyed in 1990 (1920-born TUVA cohort) and in 2010 (1940-born UTUVA cohort). Associations between education and BP were assessed using first ANOVA and post-hoc Tukey tests and then multiple linear regression, adjusted for age, gender, smoking, and body mass index. Analyses included 668 TUVA and 862 UTUVA participants.</div></div><div><h3>Results</h3><div>In the TUVA cohort (67.7 % women, mean age 70.9), 77.7 % had primary education only, compared to 54.1 % in the UTUVA cohort (59.6 % women, mean age 71.4). ANOVA revealed a significant association between education level and diastolic BP in the UTUVA cohort (p = 0.04). All other ANOVA results were non-significant (p ≥ 0.14). Tertiary education did not have a significant association with BP (p ≥ 0.0544). In regression analyses, each additional year of education in UTUVA correlated with a 0.36 mmHg decrease in systolic BP (p = 0.01) and a 0.32 mmHg decrease in diastolic BP (p < 0.001).</div></div><div><h3>Conclusions</h3><div>The 1920-born cohort demonstrated no significant differences in BP across education levels, whereas in the cohort born in 1940, higher education was associated with significant but small reductions in BP. These findings suggest that education may be linked to BP, but the absolute differences across education levels are modest. The relationship between education and BP is complex, influenced by lifestyle choices and healthcare access, and requires further exploration.</div></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"25 ","pages":"Article 200412"},"PeriodicalIF":1.9,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143859991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Examining maternal and fetal outcomes across various subtypes of hypertension during pregnancy","authors":"Laith Alhuneafat , Fares Ghanem , Sneha Nandy , Sana Khan , Anushree Puttur , Ahmad Jabri , Alaq Haddad , Bhavadharini Ramu , Bethany Sabol , Jessica Schultz , Selma Carlson","doi":"10.1016/j.ijcrp.2025.200413","DOIUrl":"10.1016/j.ijcrp.2025.200413","url":null,"abstract":"<div><h3>Introduction</h3><div>Hypertensive disorders of pregnancy (HDP) are a leading cause of maternal morbidity and mortality worldwide. It includes chronic hypertension (CH), gestational hypertension (GH), preeclampsia (PRE), and CH with superimposed preeclampsia (SPE).We aim to assess in-hospital maternal and fetal outcomes of women in each of these groups in comparison to normotensive controls.</div></div><div><h3>Methods</h3><div>Study sample included women in the National Inpatient Sample dataset from 2016 to 2020 who were categorized into the 4 groups of HDP as described above. They were compared to normotensive pregnancies for maternal and fetal outcomes using regression analysis after adjusting for age, race, C-section status, and comorbidities.</div></div><div><h3>Results</h3><div>The study dataset from October 2015–December 2020 included 19,089,780 delivery admissions with 2,771,809 (14.5 %) of patients affected by HDP. The HDP groups were distributed as follows: GH - 38 %, PRE - 32 %, SPE - 11 %, and CH - 19 %. Women with PRE, SPE, and CH had significantly higher rates of mortality, circulatory shock, peripartum cardiomyopathy, acute kidney injury, preterm labor, stillbirth, and cerebrovascular events as compared to normotensive patients, while GH did not. Specifically, maternal mortality was highest in the SPE group (adjusted odds ratio [aOR] 3.16), followed by PRE (aOR 2.91) and CH (aOR 2.42). Additionally, all HDP groups had higher rates of small for gestational age and significant bleeding as compared to normotensive patients.</div></div><div><h3>Conclusions</h3><div>Pregnant patients with CH, PRE, and SPE experience higher rates of adverse maternal and fetal outcomes during their delivery admission when compared to normotensive patients. Understanding the graded risk differences across HDP subtypes may enable more tailored interventions, optimizing maternal and fetal outcomes for those at highest risk.</div></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"25 ","pages":"Article 200413"},"PeriodicalIF":1.9,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143877117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Too much or too little: The U-shaped link between sleep duration and hypertension risk in Asian populations","authors":"Jose Eric M. Lacsa","doi":"10.1016/j.ijcrp.2025.200411","DOIUrl":"10.1016/j.ijcrp.2025.200411","url":null,"abstract":"","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"25 ","pages":"Article 200411"},"PeriodicalIF":1.9,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143859992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rising hypertension among young adults: Addressing risk perception and promoting prevention","authors":"John Patrick C. Toledo","doi":"10.1016/j.ijcrp.2025.200409","DOIUrl":"10.1016/j.ijcrp.2025.200409","url":null,"abstract":"","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"25 ","pages":"Article 200409"},"PeriodicalIF":1.9,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143864859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Obesity in the Philippines: Addressing Cardiovascular risks through healthy lifestyle","authors":"John Patrick C. Toledo","doi":"10.1016/j.ijcrp.2025.200408","DOIUrl":"10.1016/j.ijcrp.2025.200408","url":null,"abstract":"","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"25 ","pages":"Article 200408"},"PeriodicalIF":1.9,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143845162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A harmless and flavorful smoke? Young adults’ use of e-cigarettes in developing countries","authors":"Dalmacito A. Cordero Jr.","doi":"10.1016/j.ijcrp.2025.200410","DOIUrl":"10.1016/j.ijcrp.2025.200410","url":null,"abstract":"","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"25 ","pages":"Article 200410"},"PeriodicalIF":1.9,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143845161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ali Bin Abdul Jabbar , Daniyal Ali Khan , May Li-Jedras , Amjad Kabach , Ahmed Aboeata
{"title":"Trends of infective endocarditis mortality in young adult population of US: A concerning rise and its association with substance abuse","authors":"Ali Bin Abdul Jabbar , Daniyal Ali Khan , May Li-Jedras , Amjad Kabach , Ahmed Aboeata","doi":"10.1016/j.ijcrp.2025.200404","DOIUrl":"10.1016/j.ijcrp.2025.200404","url":null,"abstract":"<div><h3>Background</h3><div>Substance Abuse (SA) is associated with Infective Endocarditis (IE) morbidity and mortality in the young adult population of the US. However, limited data is available for trends and disparities related to IE mortality and its association with SA in the young adult US population.</div></div><div><h3>Methods</h3><div>Data from the Centers for Disease Control and Prevention Wide-ranging Online Data for Epidemiologic Research were analyzed from 1999 to 2022 for IE and SA-IE-related mortality in young adults aged 15 to 44 in the US. Age-adjusted mortality rates (AAMR) per 1000,000 people were used to calculate annual percent changes (APC) using Joinpoint regression analysis. Trends were stratified by sex, race/ethnicity, age groups, census region, urbanization classification, and states.</div></div><div><h3>Results</h3><div>IE caused 22,614 deaths in the young adult population of the US between 1999 and 2022. 7235 (32.0 %) of these deaths were associated with SA. AAMR for IE-associated mortality initially decreased from 6.2 in 1999 to 4.7 in 2010. Following that it increased by almost 3 folds to reach 13.5 in 2020 and 2021. SA-IE followed a similar trend, increasing more than 5 folds from an AAMR of 1.0 in 2010 to 5.4 by 2018. Between 1999 and 2009, 15–22 % of all IE deaths were associated with SA annually, which increased to >40 % for 2016–2022. Men had higher AAMR for IE though women witnessed a bigger jump in SA-associated IE mortality. Non-Hispanic American Indian or Alaskan natives, South region, and rural population had a worse increase.</div></div><div><h3>Conclusions</h3><div>IE mortality in the young adult population of the US has increased from 2010 onwards with a concerning rise in SA and IE-associated deaths.</div></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"25 ","pages":"Article 200404"},"PeriodicalIF":1.9,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143854376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}