Journal of Pediatric Hematology-Oncology Nursing最新文献

{"title":"The Effect of Storytelling on Anxiety Level of Children With Cancer: One-Group Pretest-Posttest Study.","authors":"Merve Kurt, Tuba Arpaci","doi":"10.1177/27527530261448508","DOIUrl":"10.1177/27527530261448508","url":null,"abstract":"<p><p>BackgroundThis one-group pretest-posttest experimental research was conducted to determine the effect of storytelling on the anxiety levels of children diagnosed with cancer.MethodChildren aged 4-10 years and their parents in the pediatric hematology-oncology service of a university hospital were included in the study (<i>N</i> = 39). A 2-day storytelling intervention with the <i>A Hopeful Cloud Story</i> book to help children express their anxieties and cope with the changes caused by hospitalization for cancer treatment was applied to children. The Child Fear Scale (CFS) was used to evaluate the anxiety levels of children before and after the intervention.ResultsThe average age of the children was <i>M</i> (<i>SD</i>) = 6.54 (2.11) years, and most were male (56.4%). According to the children's reports, the CFS pretest mean score was <i>M</i> (<i>SD</i>) = 3.54 (0.55), and the posttest mean score was <i>M</i> (<i>SD</i>) = 1.33 (0.48). In the posttest, it was determined that the children's CFS scores decreased (<i>p</i> < .001). According to parent and researcher reports, a significant decrease was observed in the children's CFS scores after the intervention.DiscussionAs a result, the storytelling intervention is effective in reducing children's anxiety levels. It would be helpful to use a storytelling intervention in the treatment and care processes of children with cancer.</p>","PeriodicalId":29692,"journal":{"name":"Journal of Pediatric Hematology-Oncology Nursing","volume":" ","pages":"216-223"},"PeriodicalIF":1.6,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148266364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medication Adherence in Pediatric Sickle Cell Disease and Hematopoietic Stem Cell Transplantation: An Integrative Review of Literature.","authors":"Misty Evans, Samereh Abdoli, Micah Skeens, Dominique Bulgin, Lisa C Lindley","doi":"10.1177/27527530261448518","DOIUrl":"10.1177/27527530261448518","url":null,"abstract":"<p><p>BackgroundWith the emergence of haploidentical transplantation, children with sickle cell disease (SCD) are increasingly pursuing hematopoietic stem cell transplantation (HSCT) as a curative treatment approach. However, suboptimal medication adherence remains a persistent challenge in both SCD and HSCT populations. Adherence to complex medication regimens is crucial to reducing the risk of severe complications and early mortality, yet no synthesis has evaluated patterns of adherence among patients with SCD post-HSCT.MethodWe conducted an integrative review, searching PubMed, CINAHL, and PsycINFO from April 2025 to May 2025 for studies measuring medication adherence in children (≤21 years) with SCD and/or HSCT. Studies were included if they reported adherence rates and excluded if they involved adherence interventions or drug development trials.ResultsEighteen studies met inclusion criteria: 12 addressed SCD and 6 focused on HSCT. No studies specifically examined adherence in patients with SCD post-HSCT. Adherence rates to disease-modifying medications in SCD ranged from 10% to 89%, while post-HSCT adherence ranged from 40% to 73%. Nonadherence was associated with increased complications across both populations.DiscussionThese findings highlight a critical research gap and provide a foundation for targeted adherence interventions. Addressing this gap is essential to advance nursing practice, improve adherence, and optimize clinical outcomes in pediatric hematology and HSCT care.</p>","PeriodicalId":29692,"journal":{"name":"Journal of Pediatric Hematology-Oncology Nursing","volume":" ","pages":"245-257"},"PeriodicalIF":1.6,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148273140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predisposing, Precipitating, Perpetuating, and Protective Factors Associated With Distress in the Siblings of Children With Cancer: A Systematic Review.","authors":"Isabella Zaffino, Mackenzie Murawsky, Dawn Stacey, Gail Macartney, Elham Hashemi, Christina Di Carlo, Lindsey Sikora, Lauren Mulrooney, Maria Gladkikh, Victoria Sanderson, Kyobin Hwang, Sasha Mazzarello, Maya Bristoll, Michaela Beaudry, Lindsay Jibb","doi":"10.1177/27527530261448461","DOIUrl":"https://doi.org/10.1177/27527530261448461","url":null,"abstract":"<p><p>BackgroundSiblings in families caring for a child with cancer have unique childhood experiences, often resulting in high levels of anxiety, depression, and posttraumatic stress symptoms.ObjectiveThis systematic review aims to summarize and categorize factors related to increased and decreased experiences of emotional distress among siblings of children with cancer.MethodUsing the Cochrane method, searches were conducted in six academic databases. Eligible studies included those examining siblings of children with cancer aged 21 years old or younger and on active treatment and reported on factors associated with sibling experiences of distress. Identified factors were categorized in accordance with the 4Ps of case formulation (predisposing, precipitating, perpetuating, and protective factors). Results were reported using a narrative synthesis.ResultsOf 18,059 studies retrieved, we included 12 articles. In total, 19 factors were identified, including 7 predisposing factors (e.g., sibling age), 1 precipitating factor (sibling perception of threat to lifestyle), 8 perpetuating factors (e.g., increased caregiving burden), and 3 protective factors (e.g., greater time elapsed since diagnosis). Predisposing, precipitating, and perpetuating factors increased sibling distress, while protective factors reduced sibling distress.ConclusionWe identified factors associated with distress in siblings of children with cancer. The findings may enable clinicians to identify siblings at greater risk of experiencing distress and inform the creation of psychosocial interventions that decrease experiences of distress in siblings.</p>","PeriodicalId":29692,"journal":{"name":"Journal of Pediatric Hematology-Oncology Nursing","volume":"43 4","pages":"224-235"},"PeriodicalIF":1.6,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148832921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Screening of Cognitive Symptoms During Treatment for Childhood Leukemia Predicts Post-Treatment Cognitive Functioning.","authors":"Alyssa Krentzel, Joan Yu, Olga A Taylor, Chi-Fan Lin, Emily Mason, Marilyn Hockenberry, Michael E Scheurer, Austin L Brown, Kimberly P Raghubar","doi":"10.1177/27527530261448462","DOIUrl":"10.1177/27527530261448462","url":null,"abstract":"<p><p>BackgroundThe current study describes the trajectory of caregiver-reported cognitive functioning for children treated for acute lymphoblastic leukemia (ALL) and correlations with post-treatment caregiver-reported and performance-based cognitive functioning.MethodThe PROMIS parent proxy cognitive function questionnaire was collected at four time points during childhood ALL treatment for 40 participants who also completed post-treatment PROMIS parent proxy reports and neurocognitive evaluations.ResultsPatients (52.5% male) were diagnosed with standard (45.0%) or high-risk B-ALL (47.5%) at a mean age of 7.80 years. During the first year of treatment, caregiver reports revealed a statistically significant (<i>p</i> < .01) decline in child cognitive functioning of 0.37 <i>SD</i> (95% CI: [0.12-0.62]) evaluated using mixed-effects linear regression. Caregiver report of cognitive functioning at the end of the first year of treatment correlated with post-treatment ratings (<i>p</i> < .05), after accounting for demographic and clinical factors. Post-treatment caregiver-reported cognitive functioning was significantly associated with estimated IQ (<i>p</i> < .01), attention (<i>p</i> < .05), word reading (<i>p</i> < .05), and calculation (<i>p</i> < .01).DiscussionTreatment for childhood ALL results in subtle changes in caregiver perception of cognitive functioning that are detectable shortly after diagnosis and may persist into survivorship. Furthermore, this study presents preliminary evidence for use of the PROMIS parent proxy cognitive function questionnaire as a screener for cognitive difficulties that may require further neurocognitive monitoring or comprehensive evaluation.</p>","PeriodicalId":29692,"journal":{"name":"Journal of Pediatric Hematology-Oncology Nursing","volume":" ","pages":"236-244"},"PeriodicalIF":1.6,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148537224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient Concerns on Access to Supportive Care Medicines and Symptom Management Outcomes Among Children with Cancer in Tanzania.","authors":"Deogratias M Katabalo, Jacquline Chuwa, Stanley Mwita, Antony H Liwa, Benson R Kidenya, Kristin Schroeder","doi":"10.1177/27527530251398467","DOIUrl":"10.1177/27527530251398467","url":null,"abstract":"<p><p>BackgroundPediatric cancers cause significant morbidity and mortality among children in Tanzania. Chemotherapy remains the primary treatment, but it often leads to treatment-induced toxicities that necessitate supportive care medicines. This study assessed patient-reported concerns about access to supportive medicines and evaluated symptom management outcomes among children with cancer at a major referral hospital.MethodWe conducted a descriptive cross-sectional study over 6 months among children with cancer receiving chemotherapy at Bugando Medical Centre. Data on access to and utilization of supportive care medicines and symptom relief were collected through a semi-structured questionnaire, cleaned in Microsoft Excel 2019, and analyzed with STATA Version 15.ResultsAmong 120 participants (61 female, 59 male), access to supportive care medicines was poor for 68.33%. Utilization was high at 99.17%. Most patients (62.50%) reported good symptom resolution after using supportive care medicines, whereas 37.50% continued to experience disruptions to daily activities due to chemotherapy-induced toxicities.DiscussionFinancial difficulties and limited insurance coverage contributed to poor access to supportive medicines. Despite this, utilization was high and associated with symptomatic improvement for most participants. These findings suggest that improved financial support and availability of supportive medicines could enhance symptom-management outcomes for children with cancer in Tanzania.</p>","PeriodicalId":29692,"journal":{"name":"Journal of Pediatric Hematology-Oncology Nursing","volume":" ","pages":"170-177"},"PeriodicalIF":1.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146150877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Naxitamab for Relapsed/Refractory Neuroblastoma.","authors":"Teresa Herriage, Jawhar Rawwas, Adam Sterman, Emma Hennen, Erin Bevers","doi":"10.1177/27527530251410910","DOIUrl":"10.1177/27527530251410910","url":null,"abstract":"<p><p>BackgroundChildren with relapsed/refractory (R/R) neuroblastoma are at risk for poor outcomes due to resistant disease. Naxitamab is an anti-glycolipid disialoganglioside (GD2) monoclonal antibody approved by the Food and Drug Administration for the treatment of R/R high-risk neuroblastoma. Serious adverse reactions are an expected part of treatment and include severe nerve pain during the infusion. Institutions using an interdisciplinary team approach can create a safe system for the infusion of naxitamab in the outpatient clinic setting. The purpose of this article is to present this immunotherapy, naxitamab, its adverse events (AEs), and one institution's approach in administering naxitamab in an outpatient infusion center.MethodAn interdisciplinary team, led by a pediatric oncology advanced practice nurse, developed a detailed standardized care plan that can be tailored to the patient's previous history with pain medications and response to naxitamab. The team includes multiple nursing roles, physician specialists, pharmacists, psychosocial staff, and the patient and family; each team member is educated in their defined role.ResultsAEs can be effectively managed, and naxitamab infusions can be safely infused in the outpatient infusion center through repeated cycles of treatment. Patients can be discharged to home 2 hr after the completion of the infusion.DiscussionOutpatient administration of naxitamab requires exact planning and implementation by a well-prepared interdisciplinary team. This approach supports patients and families in maximizing their quality of life through ambulatory care.</p>","PeriodicalId":29692,"journal":{"name":"Journal of Pediatric Hematology-Oncology Nursing","volume":" ","pages":"189-197"},"PeriodicalIF":1.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146228989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implementation and Evaluation of a Patient Acuity Tool in Pediatric Oncology.","authors":"Yan Yin Lim, Sharron L Docherty, Joanne Jovina Siow Huey Cheng, Barbara Turner","doi":"10.1177/27527530251408820","DOIUrl":"10.1177/27527530251408820","url":null,"abstract":"<p><p>BackgroundThe complexity of pediatric cancer care, combined with inequitable workload distribution and varying patient acuity, can contribute to dissatisfaction and physical and emotional exhaustion among nurses. In contrast to the traditional methods of assigning patients based on nurse-to-patient ratios, the evidence has collectively emphasized the importance of considering patient acuity levels in staffing decisions. Patient acuity tool (PAT) assignment approach has the potential to boost nurse job satisfaction by ensuring safer patient assignments and providing real-time data on staffing needs for workload planning. This project aims to evaluate the feasibility and effectiveness of implementing a validated PAT adapted for local context in a pediatric oncology unit.MethodThe quality improvement (QI) project utilized a pre-post interventional design. The Plan-Do-Study-Act cycle was used to guide its QI efforts in evaluating the utilization rate of PAT, and the effect of implementing PAT on nursing satisfaction, perceived equity of workload and nursing assignment.ResultsA median weekly compliance rate of 88% over the 24-week implementation period was achieved, demonstrating sustained implementation. There was an overall significant improvement in nurses' perceived workload, <i>F</i>(2, 162) = 12.86, <i>p</i> < .001; perceived equity of assignment, <i>F</i>(2, 162) = 16.08, <i>p</i> < .001; and satisfaction with work environment, <i>F</i>(2, 162) = 6.35, <i>p</i> = .002, scores following PAT implementation.DiscussionThe project demonstrated the feasibility and clinical significance of implementing a PAT assignment approach to enhance the nursing practice environment and nurses' job satisfaction in a pediatric oncology unit.</p>","PeriodicalId":29692,"journal":{"name":"Journal of Pediatric Hematology-Oncology Nursing","volume":" ","pages":"178-188"},"PeriodicalIF":1.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146195601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health Care Provider-Delivered Educational Interventions in Pediatric Oncology: A Rapid Scoping Review of Content, Feasibility, Acceptability, and Effectiveness.","authors":"Alicia Kilfoy, Rachel Hamilton, Melissa Howlett, Benita Yi, Sue Zupanec, Lindsay Jibb","doi":"10.1177/27527530261424175","DOIUrl":"https://doi.org/10.1177/27527530261424175","url":null,"abstract":"<p><p>BackgroundChildren with cancer and their families face complex medical, emotional, and practical challenges. Education delivered by health care providers is a critical component of high-quality pediatric oncology care, yet the scope, feasibility, acceptability, and effectiveness of such interventions are not well characterized. We aimed to synthesize the literature on health care provider-delivered educational interventions for children with cancer and their families, focusing on intervention content, the purpose of interventions; intervention feasibility and acceptability for implementation and evaluation; and intervention effectiveness on participant outcomes.MethodWe conducted a rapid scoping review of empirical studies published between 2013 and 2024 using PubMed, PsycInfo, and CINAHL. Studies included examined feasibility-focused educational interventions delivered by health care professionals to children with cancer and/or their caregivers. Data were extracted and analyzed descriptively using the domains of the Fitch and Steele Supportive Care Framework to categorize educational content.ResultsThirty-five articles (32 unique studies) were included. Most studies enrolled caregivers, predominantly mothers, and over half of the identified interventions were delivered remotely. Educational content frequently addressed psychological (71%) and social (43%) needs, with less attention tophysical, medical, practical, and spiritual domains. Most (84%) interventions were deemed feasible. Of 24 articles examining effectiveness, 97% reported positive family health-related impacts, particularly on anxiety, stress, and care giver knowledge outcomes.DiscussionEducational interventions appear feasible, acceptable, and well-received, with early evidence of effectiveness. Future research should prioritize theory-informed design, standardized feasibility/acceptability metrics, inclusive reporting, and the assessment of long-term and equitable impacts across diverse populations of children and families.</p>","PeriodicalId":29692,"journal":{"name":"Journal of Pediatric Hematology-Oncology Nursing","volume":"43 3","pages":"129-160"},"PeriodicalIF":1.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148259770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient Utilization and Satisfaction of Supportive Skin Care Products Among Children with Cancer Receiving Mitogen-Activated Protein Kinase Pathway Inhibitors.","authors":"Ashley Meyer, Andrea Ogle, Andrew Cluster, Amy E Armstrong, Evan Cantor, Bryan A Sisk, Nicole M Brossier, Mary Beck, Michele McHugh, Mohamed S Abdelbaki, Carrie C Coughlin","doi":"10.1177/27527530261424179","DOIUrl":"https://doi.org/10.1177/27527530261424179","url":null,"abstract":"<p><p>BackgroundDrugs that target the mitogen-activated protein kinase pathway have caused frequent and significant skin toxicity, which has led to increased burden on both patients and their caregivers. Routine skin care products for daily use have been shown to improve skin toxicity. If a patient is provided with basic skin care products for daily use this could facilitate skin management while on these medications.MethodParticipants 0-21 years old who were treated with any medication targeting the mitogen-activated protein kinase (MAPK) pathway were eligible for this prospective, single-site study. Each participant received a complimentary skin care kit consisting of skin, hair, and oral care items. The utilization of these skin care kits was evaluated and participant satisfaction with the items was measured. Secondarily, the participants' quality of life (QOL) was assessed and the participants' adherence to their MAPK inhibitor was evaluated.ResultsSeventeen participants (10 male, 7 female) with a median age of 10.5 years were enrolled. Forty-seven percent of participants rated their satisfaction with the kit as excellent, and no patient rated it as poor. Seventy-seven percent of participants rated the kit helpful, and the majority (76.5%) thought the kits should be distributed before the initiation of therapy. QOL changes were not statistically significant.ConclusionsParticipants on MAPK inhibitors who received skin care kits were satisfied with the kits' ability to help with their skin side effects. Given the high satisfaction and acceptability, future studies should evaluate the effect of these kits on QOL with adequate power to detect improvements.</p>","PeriodicalId":29692,"journal":{"name":"Journal of Pediatric Hematology-Oncology Nursing","volume":"43 3","pages":"161-169"},"PeriodicalIF":1.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148259820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nurse-Specific Assessment and Management of Neurotoxicity Associated With Immunotherapy: An Integrative Literature Review.","authors":"Erin A Armideo, Kristen L Dalton, Shannon L Markert, Clifton P Thornton","doi":"10.1177/27527530251415179","DOIUrl":"10.1177/27527530251415179","url":null,"abstract":"<p><p><b>Background:</b> Precision-based immunotherapy agents are frequently being incorporated into upfront cancer treatment, and neurotoxicities have emerged as potential serious adverse effects. With this realization, nurses must augment their care to adopt a similar personalized, precision approach with unique neurotoxicity monitoring and intervention. This review aims to synthesize the existing body of literature that directs nurse-led neurotoxicity monitoring and intervention specific to immunotherapies. <b>Method:</b> A comprehensive literature search was conducted with a search strategy designed to identify clinical nursing care guidelines for assessment of immunotherapy-associated neurotoxicity in pediatrics and young adult oncology. The search was designed in three tiers to identify articles that addressed domains of (a) pediatric oncology, (b) immunotherapy, and (c) nursing guidelines. <b>Results:</b> Initially, 360 unique articles were identified, and 8 met the inclusion criteria. Most articles were narrative reviews and data-informed commentaries, with some longitudinal studies and a systematic review; all were of moderate to good quality. Many toxicities were discussed under the general terminology of neurotoxicities, with limited description of neurotoxicities specific to agents or classes. Few evidence-based recommendations for nurse-led monitoring and interventions exist. <b>Conclusions:</b> Immunotherapy agents have quickly become incorporated into the standard of care for many pediatric cancers. To appropriately monitor, intervene, and treat these toxicities, nurses must be aware of the neurological side effects specific to each agent and adjust care accordingly to individual patient needs while receiving these agents. Additional research is needed to develop, implement, and test monitoring protocols specific to neurotoxicities with immunotherapy in pediatrics.</p>","PeriodicalId":29692,"journal":{"name":"Journal of Pediatric Hematology-Oncology Nursing","volume":" ","pages":"92-105"},"PeriodicalIF":1.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146221334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}